CN114983887A - Beautiful and light herbal liquid - Google Patents

Beautiful and light herbal liquid Download PDF

Info

Publication number
CN114983887A
CN114983887A CN202210601371.XA CN202210601371A CN114983887A CN 114983887 A CN114983887 A CN 114983887A CN 202210601371 A CN202210601371 A CN 202210601371A CN 114983887 A CN114983887 A CN 114983887A
Authority
CN
China
Prior art keywords
composition
extract
skin
maltodextrin
citric acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202210601371.XA
Other languages
Chinese (zh)
Inventor
李清芬
施展
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Guangzhou Maijiaxin Biotechnology Co ltd
Original Assignee
Guangzhou Maijiaxin Biotechnology Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Guangzhou Maijiaxin Biotechnology Co ltd filed Critical Guangzhou Maijiaxin Biotechnology Co ltd
Priority to CN202210601371.XA priority Critical patent/CN114983887A/en
Publication of CN114983887A publication Critical patent/CN114983887A/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/194Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716Glucans
    • A61K31/718Starch or degraded starch, e.g. amylose, amylopectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/63Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A61K36/634Forsythia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36Carboxylic acids; Salts or anhydrides thereof
    • A61K8/365Hydroxycarboxylic acids; Ketocarboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/42Amides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/732Starch; Amylose; Amylopectin; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/06Preparations for care of the skin for countering cellulitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • A61K2800/5922At least two compounds being classified in the same subclass of A61K8/18

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Birds (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Medical Informatics (AREA)
  • Dermatology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Diabetes (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a beautiful and light herbal liquid, and relates to the technical field of skin external products; the beautifying and slimming herbal liquid comprises a combination of fructus forsythiae extract, maltodextrin, golden yellow chamomile extract and citric acid. The herbal liquid with light beautiful appearance is beneficial to improving the internal environment of the intestinal tract, enhancing the function of the intestinal tract, improving the function of the whole digestive system, promoting the elimination of waste, accelerating the combustion of fat, and fundamentally improving the metabolism in the body, thereby essentially achieving the effects of losing weight and reducing fat.

Description

Herbal liquid for beautifying and slimming
Technical Field
The invention relates to the technical field of skin external products, in particular to a beautiful and light herbal liquid.
Background
Along with the progress and development of society, the living standard of people is higher and higher, the proportion of the people suffering from the autologous lipodystrophy is increased, and the physiology and the psychology of people are burdened.
The obesity not only affects the body beauty, but also reduces the personal charm due to the body shape deformation caused by the obesity, and causes much inconvenience in personal life; meanwhile, obesity brings psychological damage to people, obese people are easy to reject and jeer, obese people rarely participate in social activities for self-respect protection, and are isolated and distant from other people in schools and societies, which can cause bad influence on career and love over time, so people pay more attention to body beauty and physical and mental health.
At present, main measures for losing weight are as follows: 1. changing lifestyle, controlling diet, reducing fat intake, balancing diet, and burning fat with exercise; 2. the drug therapy is an appetite inhibitor which can act on the center, generally an anorexia drug, and acts on peripheral lipase inhibition, and the aim of losing weight is achieved by blocking fat absorption in diet.
Most of various weight-reducing products in the market, such as variegated foods, medicines, health-care products and the like, adopt methods of controlling appetite or diarrhea and the like to achieve the purpose of reducing weight, are easy to cause malnutrition and are harmful to body health.
Disclosure of Invention
In order to overcome the defects of the prior art, the invention provides a herbal liquid for beautifying and lightening. The herbal liquid with light beautiful appearance is beneficial to improving the internal environment of the intestinal tract, enhancing the function of the intestinal tract, improving the function of the whole digestive system, promoting the elimination of waste, accelerating the combustion of fat, and fundamentally improving the metabolism in the body, thereby essentially achieving the effects of losing weight and reducing fat.
In order to solve the above problems, the present invention proposes the following technical solutions:
in a first aspect, the present invention provides the use of a combination of forsythia suspense extract, maltodextrin, chamomile extract and citric acid for the preparation of a composition for external application to the skin having a metabolism-promoting effect.
Preferably, in the skin external composition, the forsythia suspense extract is contained in an amount of 1 to 5%, the maltodextrin is contained in an amount of 2 to 6%, the chamomile extract is contained in an amount of 3 to 6%, and the citric acid is contained in an amount of 0.1 to 1%, based on the total weight of the skin external composition.
More preferably, in the skin external composition, the forsythia suspense extract is contained in an amount of 2 to 4%, the maltodextrin is contained in an amount of 3 to 6%, the chamomile extract is contained in an amount of 4 to 5.5%, and the citric acid is contained in an amount of 0.6 to 1%, based on the total weight of the skin external composition.
The composition for external application to the skin described in the present invention includes, but is not limited to, pharmaceutical compositions and cosmetic compositions, preferably cosmetic compositions, more preferably skin care cosmetic compositions.
In a second aspect, the present invention provides a beautiful and light herbal liquid comprising a combination of forsythia suspensa extract, maltodextrin, chamomile extract and citric acid.
Specifically, in the beautiful light herbal liquid of the invention, forsythia suspense extract, maltodextrin, golden chamomile extract and citric acid are used as a composition with the effect of promoting metabolism, wherein the forsythia suspense extract has a remarkable anti-inflammatory effect, can remarkably inhibit inflammatory exudation and edema, can remarkably inhibit the formation of inflammatory barriers but enhance the formation of the inflammatory barriers, and can remarkably reduce the exudation of 3P marked erythrocytes from capsules; the maltodextrin has the effects of promoting metabolism, whitening skin, removing facial pigmentation, promoting discharge of body waste, loosening bowel to relieve constipation, and reducing weight and fat; maltodextrin can also increase the anti-aging property of weak acid, and reduce skin irritation caused by other acidity, thereby achieving skin tightening. The golden chamomile extract has the functions of resisting inflammation, calming, naturally reducing pains related to arthritis, injuries, backache and fever and enhancing capillary resistance; the citric acid has the effects of resisting oxidation, resisting aging, keeping moisture, supplementing water, regulating pH value of skin, effectively controlling secretion of skin oil, resisting damage of free radicals to skin, and making skin smooth, white, tender and fine. In the invention, the addition of citric acid can also promote the skin to absorb the forsythia suspense extract, maltodextrin and golden chamomile extract.
The applicant finds that the above four components act synergistically to have significant effects in improving the function of the digestive system, promoting the removal of waste products, and accelerating the combustion of fats.
In the invention, the applicant finds out through experiments that the corresponding effect cannot be achieved by using other similar regulators to replace citric acid to be matched with the components.
Compared with any three or any two or any one of forsythia suspense extract, maltodextrin, golden chamomile extract and citric acid, the beautifying light herbal liquid can remarkably promote metabolism, which shows that the combination of the forsythia suspense extract, the maltodextrin, the golden chamomile extract and the citric acid has a synergistic effect, and also shows that the combination is not simple replacement or superposition among the existing components.
Meanwhile, the herbal liquid for beautifying and lightening the skin is further added with hydroxyphenylpropionamide benzoic acid; the content of the hydroxyphenylpropionamide benzoic acid is 0.05 to 1.5 percent, preferably 0.1 to 1.2 percent; hydroxyphenyl propionamide benzoic acid, has antihistaminic, anti-irritant, and antipruritic effects; can effectively inhibit skin erythema, edema and pruritus caused by histamine, and improve the safety performance of the beautiful and light herbal liquid.
The application method of the herbal liquid for beautifying and lightening comprises the following steps: the product is applied to the skin of the whole body, and the skin is massaged until the product is completely absorbed.
The weight-losing and fat-reducing effects can be realized through massage, the principle of weight-losing is completely different from that of the prior method for controlling appetite or adopting diarrhea and the like, malnutrition and harm to body health can not be caused, and the safety performance is higher.
Preferably, in the beautiful light herbal liquid, the content of the forsythia suspense extract is 1-5%, the content of the maltodextrin is 2-6%, the content of the chamomile extract is 3-6%, the content of the citric acid is 0.1-1%, the content of the hydroxyphenylpropionamide benzoic acid is 0.05-1.5%, based on the total weight of the beautiful light herbal liquid.
More preferably, in the beautiful light herbal liquid, the content of the forsythia suspense extract is 2-4%, the content of maltodextrin is 3-6%, the content of the chamomile extract is 4-5.5%, the content of citric acid is 0.6-1%, and the content of hydroxyphenylpropionamide benzoic acid is 0.1-1.2%, based on the total weight of the beautiful light herbal liquid.
In a third aspect, there is provided a method for improving the metabolism promoting effect of a composition for external application to the skin, the method comprising: a combination of forsythia suspense extract, maltodextrin, golden chamomile extract and citric acid is added to a skin external composition.
By adding the forsythia extract, the maltodextrin, the golden chamomile extract and the citric acid, the skin external composition is beneficial to improving the internal environment of an intestinal tract, enhancing the function of the intestinal tract, improving the function of the whole digestive system, promoting the elimination of waste, accelerating the combustion of fat, fundamentally improving the metabolism in the body, and essentially achieving the effects of losing weight and reducing fat.
Preferably, in the skin external composition, the content of the forsythia suspense extract is 1-5%, the content of the maltodextrin is 2-6%, the content of the chamomile extract is 3-6%, and the content of the citric acid is 0.1-1%, based on the total weight of the skin external composition.
More preferably, in the composition for external application to skin, the content of forsythia suspense extract is 2 to 4%, the content of maltodextrin is 3 to 6%, the content of chamomile extract is 4 to 5.5%, and the content of citric acid is 0.6 to 1%, based on the total weight of the composition for external application to skin.
Meanwhile, the composition for external application to skin of the present invention further comprises hydroxyphenylpropionamide benzoic acid; the content of the hydroxyphenylpropionamide benzoic acid is 0.05 to 1.5 percent, and preferably 0.1 to 1.2 percent; hydroxyphenylpropionamide benzoic acid, has antihistaminic, anti-irritant and antipruritic effects; can effectively inhibit skin erythema, edema and pruritus caused by histamine, and improve the safety performance of the beautiful and light herbal liquid.
Specifically, the skin external composition is a pharmaceutical composition or a cosmetic composition.
When the skin external composition of the present invention is a cosmetic composition, the skin external composition of the present invention may optionally comprise conventional ingredients of cosmetic compositions, including any known in the art, such as vehicles, surfactants, skin care active ingredients, and cosmetic adjuvants, in addition to the above-mentioned components, and the type and amount thereof may be selected according to specific needs. Generally, the content of the conventional ingredients is 1 to 95% by weight based on the total weight of the skin external composition.
In the present invention, such vehicles are known in the art and include, but are not limited to, diluents, dispersants or carriers, and the like, including, but not limited to, ethanol, butylene glycol, dipropylene glycol, and the like. The type and amount can be selected by those skilled in the art according to the actual needs. Generally, in the composition for external application to the skin of the present invention, the vehicle accounts for 1 to 20% of the total weight of the common ingredients.
The surfactant is any type of surfactant commonly used in cosmetics for reducing the surface tension of the interface, which can achieve the purpose of cleaning, emulsifying, stabilizing the system. Such surfactants include, but are not limited to, fatty acid soaps (e.g., sodium laurate, sodium palmitate, etc.), higher alkyl sulfates (e.g., sodium lauryl sulfate, etc.), N-acyl sarcosines (e.g., sodium lauroyl sarcosinate, etc.), higher fatty acid amide sulfonates (e.g., sodium lauryl methyl taurate, etc.), alkylbenzene sulfonates, higher fatty acid ester sulfates (e.g., hardened coconut oil fatty acid sodium glycerosulfate, etc.), N-acyl glutamates, lauryl dimethylaminoacetic acid betaine, alkyl betaines, amido betaines, sorbitan fatty acid esters (e.g., sorbitan monooleate, sorbitan monoisostearate, sorbitan monolaurate, sorbitan monopalmitate, sorbitan monostearate, sorbitan oleate), PEG-alkyl ethers (e.g., PEG-2-octyl dodecyl ether, etc.), sodium sesqui sulfates, etc, Sucrose fatty acid ester, etc. For a particular surfactant, one skilled in the art can select the type and amount thereof as desired. Generally, in the composition for external application to the skin of the present invention, the surfactant is 1 to 50% by weight of the total weight of the common ingredients.
Such skin care actives are known in the art and include, but are not limited to, moisturizers, skin conditioners, emollients, and the like. The humectant includes but is not limited to one or more combinations of glycerin, trehalose, sucrose, panthenol, propylene glycol, 1, 2-pentanediol, mannitol, glycerol polyether-26, rhamnose, raffinose, erythritol, polyethylene glycol-8, polyethylene glycol-32, methyl gluceth-10, methyl gluceth-20, PEG/PPG-17/6 copolymer, sodium polyglutamate, xylitol, urea, hydrolyzed sclerotium rolfsii gum, sodium polyglutamate, glycerol glucoside, PPG-10 methyl glucose ether, pullulan, tremella polysaccharide, PPG-20 methyl glucose ether, and the like. Generally, in the composition for external application to the skin of the present invention, the moisturizer accounts for 1 to 35% of the total weight of the conventional ingredients.
The skin conditioner has effects of keeping moisture, removing wrinkle, removing speckle, eliminating acne, and controlling oil. The skin conditioning agent includes, but is not limited to, one or more combinations of phytosterol/octyldodecanol lauroyl glutamate, turmeric root extract, ceramide 2, ceramide 3, hydrolyzed sodium hyaluronate, acetyl phytosphingosine, cholesterol, allantoin, birch bark extract, hydrogenated lecithin, arbutin, acetyl phytosphingosine, resveratrol, palmetto bark extract, coleus forskohlii root extract, bisabolol, tetraisopalmitate ascorbate, pepper seed extract, ubiquinone, pyridoxine dipalmitate, pyridoxine dicaprylate, retinol palmitate, tocopherol acetate, oat kernel extract, and the like. Generally, in the skin external composition of the present invention, the skin conditioner is 0.05 to 50% by weight of the total weight of the common ingredients.
The emollients include, but are not limited to, one or more combinations of tri (ethyl hexanoate) glyceride, isopropyl lauroyl sarcosinate, caprylic/capric triglyceride, grape seed oil, meadowfoam seed oil, shea butter, cetyl alcohol, dimethicone, pentaerythritol tetra (ethyl hexanoate), olive oil, avocado oil, corn oil, dioctyl carbonate, homosalate, squalane, stearyl alcohol, isopropyl myristate, myristyl alcohol, hydrogenated polydecene, murumuru fruit oil, sunflower seed oil, isohexadecane, jojoba oil, lanolin, paraffin, microcrystalline wax, beeswax, and the like. Generally, in the skin external composition of the present invention, the emollient represents 0.05 to 50% by weight of the total weight of the conventional ingredients.
The cosmetic adjuvants include, but are not limited to, emulsifiers, thickeners, preservatives, fragrances, and the like.
Such emulsifiers include, but are not limited to, one or more combinations of sorbitan olivetoleate, steareth-21, PEG-60 hydrogenated castor oil, glyceryl stearate/PEG-100 stearate, PPG-13-decyltetraeth-24, cetearyl glucoside, polyglyceryl-10 myristate, cetearyl glucoside, polyglyceryl-10 stearate, polyglyceryl-10 dioleate, and the like. The type and amount can be specifically selected by those skilled in the art as desired.
The thickener includes, but is not limited to, one or more combinations of hydroxyethyl cellulose, hydroxypropyl cellulose, carbomer, xanthan gum, acacia, polyethylene glycol-14M, polyethylene glycol-90M, succinoglycan, acrylic acid/C10-30 alkanol acrylate crosspolymer, and the like.
The preservative includes, but is not limited to, one or more of methylparaben, propylparaben, phenoxyethanol, benzyl alcohol, phenylethyl alcohol, potassium sorbate, sodium benzoate, chlorphenesin, and the like. Generally, in the composition for external application to the skin of the present invention, the preservative is 0.01 to 5% by weight based on the total weight of the common ingredients.
When the composition for external application to the skin of the present invention is a pharmaceutical composition, the composition for external application to the skin of the present invention may optionally contain the usual ingredients of the pharmaceutical composition, including any known in the art such as pharmaceutically active ingredients, in addition to the above-mentioned components, and the type and amount thereof may be selected according to specific needs. The pharmaceutically active ingredients are ingredients known in the art for cosmetic and skin care. Generally, in the composition for external application to the skin of the present invention, the pharmaceutically active ingredient accounts for 0.05 to 85% of the total weight of the commonly used ingredients.
The preparation of the skin external composition of the present invention can be prepared by any suitable method known in the art. For example, it can be prepared using a vessel such as a dissolution tank, an emulsifying pot, a disperser, a transfer pump, etc., which are commonly used in the art. The preparation method comprises putting water soluble substance into water phase dissolving kettle, putting oil soluble substance into oil phase dissolving kettle, and heating the two kettles to about 80 deg.C respectively, wherein the raw material easy to agglomerate can be pre-dispersed with disperser. After the dissolution is finished, the oil phase and the water phase are conveyed into an emulsifying pot, and homogenized and emulsified for about 5-15 minutes. After emulsification, the temperature of the material body is reduced to normal temperature, and essence, preservative and the like are optionally added. After the relevant detection indexes are qualified, the products can be filled and delivered.
The preparation method can be deleted or adjusted according to the requirements of dosage forms. The composition can be made into pharmaceutical composition or cosmetic composition in various dosage forms such as liquid, lotion, ointment, cream or gel.
Compared with the prior art, the invention has the following beneficial effects:
the invention discloses a skin external composition (beautiful and light herbal liquid) added with forsythia extract, maltodextrin, golden yellow chamomile extract and citric acid, which is helpful for improving the internal environment of an intestinal tract, enhancing the function of the intestinal tract, improving the function of the whole digestive system, promoting the elimination of waste, accelerating the combustion of fat, and fundamentally improving the metabolism in the body, thereby essentially achieving the effects of losing weight and reducing fat and having excellent stability and safety performance.
Additional aspects and advantages of the invention will be set forth in part in the description which follows, and in part will be obvious from the description, or may be learned by practice of the invention.
Detailed Description
The technical solutions in the embodiments will be clearly and completely described below with reference to the embodiments of the present invention. It is apparent that the embodiments to be described below are only a part of the embodiments of the present invention, and not all of them. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
It will be understood that the terms "comprises" and/or "comprising," when used in this specification and the appended claims, specify the presence of stated features, integers, steps, operations, elements, and/or components, but do not preclude the presence or addition of one or more other features, integers, steps, operations, elements, components, and/or groups thereof.
It is also to be understood that the terminology used in the description of the embodiments of the invention herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the embodiments of the invention. As used in the description of embodiments of the present invention and the appended claims, the singular forms "a," "an," and "the" are intended to include the plural forms as well, unless the context clearly indicates otherwise.
The components in the embodiment of the invention are calculated according to weight percentage; the starting materials in the examples of the present invention are all commercially available.
In the following examples, sonography is referenced: [1] zhannie, Zhang Shenglan, the clinical value of intraabdominal fat was measured by ultrasound [ J ]. Shandong medicine, 1991, (03):26.
Example 1: preparing samples of experimental group and control group
In this example, composition samples (beauty light herbal solutions) having the following formulations were prepared, wherein compositions 1 to 3 were experimental groups of the present invention, and combinations 4 to 7 were control group samples, and the specific compositions are shown in table 1.
Table 1: components and amounts (%)
Figure BDA0003669392920000081
Figure BDA0003669392920000091
The preparation method of the composition comprises the following steps:
1) heating glycerol, methyl hydroxybenzoate, butanediol, allantoin and part of water to 75 deg.C to completely dissolve; after cooling, adding carbomer while stirring until carbomer is well swelled; adding fructus forsythiae extract, maltodextrin, flos Chrysanthemi extract and hydroxyphenylpropionamide benzoic acid at a certain proportion, stirring for dissolving;
2) adding citric acid after completely dissolving, adding water for supplementing, and stirring to obtain a sample (beautiful and light herbal liquid).
The application method of the herbal liquid for beautifying and lightening comprises the following steps: the product is applied to the skin of the whole body, and the skin is massaged until the product is completely absorbed.
Effect verification:
the efficacy of the compositions 1 to 7 in promoting metabolism was verified, specifically, the change in the thickness of subcutaneous fat before and after use of the user, more specifically, the change in the thickness of subcutaneous fat in the thigh region and the change in the thickness of subcutaneous fat in the abdomen region were measured.
The specific test steps are as follows:
160 female volunteers with weight of 65-70 kg and partial fat were randomly recruited to test the effect of the composition 1-7. Dividing all volunteers into 8 groups randomly, wherein the 1 st to 7 th groups are respectively corresponding to the compositions 1 to 7, and the 8 th group does not use any weight-reducing product or take any weight-reducing medicine; the thickness of the subcutaneous fat of the thigh and abdomen (test area of the same size and location) was measured using a probe and recorded by using a conventional ultrasonic measurement method, respectively. The use method of the compositions 1 to 7 is as follows: applying the product to the skin of the whole body, and massaging until the product is completely absorbed, wherein the dosage of the product is 0.2g/10cm 2 . During the test period, all volunteers can correctly use the corresponding product (diet is normal) according to the relevant requirements, and do not enable the volunteers to use the corresponding productUsing other weight-reducing products or taking weight-reducing medicines.
The thickness of the subcutaneous fat in the thigh and abdomen (test area) was measured at week 4 and week 8, respectively, using the above composition, and the specific data is shown in table 2 (data is the average of each group of volunteers).
Table 2: experimental results for compositions 1 to 7
Figure BDA0003669392920000101
In the experimental process, each volunteer synchronously records the index change conditions of the skin oil secretion degree, the weight change, the blood fat reduction and the like in the using process.
The judgment standard is as follows:
remarkably: the skin secretes oil to normal degree, the body weight is gradually recovered to normal (obviously reduced), and the blood fat is obviously reduced (the value of the triglyceride is reduced to be more than 4 mmol/L);
the method has the following advantages: reduction of oil and fat secretion from skin, reduction of body weight (insignificant), reduction of blood fat ((triglyceride value reduction of 1-4mmol/L))
And (4) invalidation: there was essentially no change before oil and body weight were secreted.
The results are shown in Table 3.
Table 3:
Figure BDA0003669392920000102
Figure BDA0003669392920000111
according to the test results in tables 2 and 3, the compositions 1 to 3 of the invention can obviously accelerate the combustion of fat, and fundamentally increase the metabolism in vivo, so that the effects of losing weight and reducing fat can be essentially achieved, while the compositions 4 to 7 adopt any two or three of forsythia extract, maltodextrin, golden chamomile extract and citric acid, and the weight-losing and fat-reducing effects of the compositions 4 to 7 are obviously inferior to those of the compositions 1 to 3. The invention shows that the combination of forsythia suspense extract, maltodextrin, golden chamomile extract and citric acid has a synergistic effect, and the combination is not the simple superposition of the existing components.
Example 2: in this example, to further verify that the compositions of the present invention have synergistic effects, control samples having the following formulations were prepared, respectively; in composition 8, the citric acid in composition 1 of the present invention was replaced with tromethamine, and the specific composition is shown in table 4.
Table 4: components and amounts (%)
Figure BDA0003669392920000112
Figure BDA0003669392920000121
The preparation method of the composition 8 comprises the following steps:
1) heating glycerol, methyl hydroxybenzoate, butanediol, allantoin and part of water to 75 deg.C to completely dissolve; after cooling, adding carbomer while stirring until carbomer is well swelled; adding fructus forsythiae extract, maltodextrin, flos Chrysanthemi extract and hydroxyphenylpropionamide benzoic acid at a certain proportion, stirring for dissolving;
2) adding tromethamine after completely dissolving, adding water for complementing, and uniformly stirring to obtain a sample (beautiful and light herbal liquid).
The application method of the herbal liquid for beautifying and lightening comprises the following steps: the product is applied to the skin of the whole body, and is massaged until the product is completely absorbed.
The same experiment was carried out under the same conditions (number of test persons and time) for composition 8 with reference to the effect verification of compositions 1 to 7 in example 1, and the experimental results are shown in tables 5 and 6.
Table 5:
Figure BDA0003669392920000122
table 6:
group of Show effect Is effective Invalidation
Blank group 0 0 20
Composition 1 20 0 0
Composition 8 6 12 2
According to the test results in tables 5 and 6, it can be seen that citric acid is required to be used in combination with forsythia suspense extract, maltodextrin and golden yellow chamomile extract to achieve a synergistic effect, and the principle of the synergistic effect is that the citric acid not only can better exert the effects of the forsythia suspense extract, the maltodextrin and the golden yellow chamomile extract, but also can promote the skin to absorb the forsythia suspense extract, the maltodextrin and the golden yellow chamomile extract, so that the effects of the composition on increasing the metabolism in vivo and losing weight and reducing fat are remarkably improved.
The invention synchronously verifies the influence of other pH regulators, plant extracts, traditional Chinese medicine extracts and the like on the composition in the experimental process, and test results show that the synergistic effect is achieved only by using the forsythia suspensa extract, the maltodextrin, the golden chamomile extract and the citric acid in a matching way. Meanwhile, the composition of the invention can pass the related tests of stability and irritation, and has excellent stability and safety performance.
In conclusion, the composition of forsythia suspense extract, maltodextrin, golden chamomile extract and citric acid has a synergistic effect, and the composition is not a simple replacement among the existing components.
The technical solutions provided by the embodiments of the present invention are described in detail above, and the principles and embodiments of the present invention are explained herein by using specific examples, and the descriptions of the embodiments are only used to help understanding the principles of the embodiments of the present invention; meanwhile, for a person skilled in the art, according to the embodiments of the present invention, there may be variations in the specific implementation manners and application ranges, and in summary, the content of the present description should not be construed as a limitation to the present invention.

Claims (10)

1. Use of a combination of forsythia suspense extract, maltodextrin, golden chamomile extract and citric acid for the preparation of a skin external composition having a metabolism-promoting effect.
2. The use according to claim 1, wherein the composition for external application to the skin comprises 1 to 5% of the forsythia suspensa extract, 2 to 6% of the maltodextrin, 3 to 6% of the chamomile extract, and 0.1 to 1% of the citric acid, based on the total weight of the composition for external application to the skin.
3. The use according to claim 1 or 2, wherein in the composition for external application to the skin, the content of the forsythia suspense extract is 2 to 4%, the content of the maltodextrin is 3 to 6%, the content of the chamomile extract is 4 to 5.5%, and the content of the citric acid is 0.6 to 1%, based on the total weight of the composition for external application to the skin.
4. The beautifying light herbal liquid is characterized by comprising a combination of fructus forsythiae extract, maltodextrin, golden yellow chamomile extract and citric acid.
5. The beauty light herbal liquid as claimed in claim 4, wherein the beauty light herbal liquid contains fructus forsythiae extract 1-5%, maltodextrin 2-6%, chamomile extract 3-6%, and citric acid 0.1-1%, based on the total weight of the beauty light herbal liquid.
6. The beautiful light herbal liquid as claimed in claim 4 or 5, wherein in the beautiful light herbal liquid, the content of the forsythia suspensa extract is 2-4%, the content of the maltodextrin is 3-6%, the content of the chamomile extract is 4-5.5%, and the content of the citric acid is 0.6-1% based on the total weight of the beautiful light herbal liquid.
7. A method for improving the metabolism promoting effect of a skin external composition, characterized in that a combination of forsythia suspense extract, maltodextrin, golden chamomile extract and citric acid is added to the skin external composition.
8. The method of claim 7, wherein the composition for external application to the skin comprises 1 to 5% of forsythia suspensa extract, 2 to 6% of maltodextrin, 3 to 6% of chamomile extract, and 0.1 to 1% of citric acid, based on the total weight of the composition for external application to the skin.
9. The method of claim 7, wherein the composition for external application to the skin comprises 2 to 4% of forsythia suspensa extract, 3 to 6% of maltodextrin, 4 to 5.5% of chamomile extract, and 0.6 to 1% of citric acid, based on the total weight of the composition for external application to the skin.
10. The method according to any one of claims 7 to 9, wherein the composition for external application to the skin is a pharmaceutical composition or a cosmetic composition.
CN202210601371.XA 2022-05-30 2022-05-30 Beautiful and light herbal liquid Pending CN114983887A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202210601371.XA CN114983887A (en) 2022-05-30 2022-05-30 Beautiful and light herbal liquid

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202210601371.XA CN114983887A (en) 2022-05-30 2022-05-30 Beautiful and light herbal liquid

Publications (1)

Publication Number Publication Date
CN114983887A true CN114983887A (en) 2022-09-02

Family

ID=83030722

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202210601371.XA Pending CN114983887A (en) 2022-05-30 2022-05-30 Beautiful and light herbal liquid

Country Status (1)

Country Link
CN (1) CN114983887A (en)

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1876178A (en) * 2006-04-27 2006-12-13 北京东方兴企食品工业技术有限公司 Granule with beauty and health function
CN101507690A (en) * 2008-12-26 2009-08-19 扬州市中汇化妆品有限公司 Bath dew for baby
CN104645278A (en) * 2013-11-25 2015-05-27 詹其旸 Healthcare herbal tea
CN107441390A (en) * 2017-06-16 2017-12-08 广州中晟生物科技有限公司 A kind of fat burning and slimming frost and preparation method
CN108114029A (en) * 2018-02-08 2018-06-05 陕西中医药大学 A kind of active Chinese drug component compositions, its preparation method and its application
CN109223681A (en) * 2018-11-22 2019-01-18 广州森麦生物科技有限公司 A kind of multiple-effect skin care compositions and the application in cosmetics
CN109419685A (en) * 2017-08-31 2019-03-05 张忠远 A kind of manufacturing method of essential oil toxin expelling moisturizing nursing honey
CN111012682A (en) * 2019-12-23 2020-04-17 苏州绿叶日用品有限公司 Slimming nano liposome and preparation method and application thereof

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1876178A (en) * 2006-04-27 2006-12-13 北京东方兴企食品工业技术有限公司 Granule with beauty and health function
CN101507690A (en) * 2008-12-26 2009-08-19 扬州市中汇化妆品有限公司 Bath dew for baby
CN104645278A (en) * 2013-11-25 2015-05-27 詹其旸 Healthcare herbal tea
CN107441390A (en) * 2017-06-16 2017-12-08 广州中晟生物科技有限公司 A kind of fat burning and slimming frost and preparation method
CN109419685A (en) * 2017-08-31 2019-03-05 张忠远 A kind of manufacturing method of essential oil toxin expelling moisturizing nursing honey
CN108114029A (en) * 2018-02-08 2018-06-05 陕西中医药大学 A kind of active Chinese drug component compositions, its preparation method and its application
CN109223681A (en) * 2018-11-22 2019-01-18 广州森麦生物科技有限公司 A kind of multiple-effect skin care compositions and the application in cosmetics
CN111012682A (en) * 2019-12-23 2020-04-17 苏州绿叶日用品有限公司 Slimming nano liposome and preparation method and application thereof

Similar Documents

Publication Publication Date Title
CN111249209B (en) Moisturizing repair cream and preparation method thereof
CN103237555B (en) Topical skin care formulation
WO2018196481A1 (en) Moisturizing cosmetics composition
KR101910482B1 (en) Topical skin care formulations comprising jaboticaba and cashew fruit pulps and extracts thereof
IL260028B1 (en) Skin care preparations for babies
KR101015702B1 (en) Compositions comprising Seaweeds extract for improving and alleviating inflammation and irritation of skin
CN110731974B (en) Skin external composition with enhanced anti-inflammatory efficacy
CN104586735A (en) Method for preparing fermented product filtrate by fermenting rice with lactobacillus casei, and application of fermented product filtrate
EA006440B1 (en) Agent for treating, caring and preventing possible damaged skin tissues, process for the production thereof and use
CN111801108A (en) Topical skin care compositions
CN110650724A (en) Composition for promoting melanogenesis comprising Cirsium japonicum extract as active ingredient
CN106333880B (en) toner based on thin emulsion and preparation method thereof
KR20090130584A (en) Cosmetic composition comprising an extract of mixed herbs having skin whitening and wrinkle improving activity
TW201200032A (en) Hyaluronic acid production promoting agent
KR100776755B1 (en) Composition comprising crude drug extract showing anti-itching effect
CN109453088B (en) Whitening and firming cream, preparation method thereof and tyrosinase inhibitor
CA2731138C (en) Compositions for treating rosacea
CN110101587A (en) A kind of anti-inflammatory anti-acne facial treatment milk
CN114983887A (en) Beautiful and light herbal liquid
KR20160036834A (en) Skin external application composition comprising complex fermented extract of crude drug ingredients
CN112656728A (en) Anti-allergy relieving liquid and preparation method thereof
KR101814537B1 (en) A skin topical composition comprising the bio-cellulose powder for reducing and preventing cellulite
KR101814538B1 (en) A cosmentic composition comprising the bio-cellulose powder for reducing and preventing cellulite
CN114984101A (en) Beautiful gel
CN114099410B (en) Face cream composition of liposome with synergistic gain and anti-aging effects and preparation method thereof

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication

Application publication date: 20220902

RJ01 Rejection of invention patent application after publication