CN110101587A - A kind of anti-inflammatory anti-acne facial treatment milk - Google Patents

A kind of anti-inflammatory anti-acne facial treatment milk Download PDF

Info

Publication number
CN110101587A
CN110101587A CN201910490632.3A CN201910490632A CN110101587A CN 110101587 A CN110101587 A CN 110101587A CN 201910490632 A CN201910490632 A CN 201910490632A CN 110101587 A CN110101587 A CN 110101587A
Authority
CN
China
Prior art keywords
parts
acne
facial treatment
treatment milk
component
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201910490632.3A
Other languages
Chinese (zh)
Inventor
陶华
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Guangzhou Yulin Cosmetics Co Ltd
Original Assignee
Guangzhou Yulin Cosmetics Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Guangzhou Yulin Cosmetics Co Ltd filed Critical Guangzhou Yulin Cosmetics Co Ltd
Priority to CN201910490632.3A priority Critical patent/CN110101587A/en
Publication of CN110101587A publication Critical patent/CN110101587A/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/35Ketones, e.g. benzophenone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37Esters of carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37Esters of carboxylic acids
    • A61K8/375Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/41Amines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4946Imidazoles or their condensed derivatives, e.g. benzimidazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/678Tocopherol, i.e. vitamin E
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/89Polysiloxanes
    • A61K8/891Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005Antimicrobial preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/008Preparations for oily skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Cosmetics (AREA)

Abstract

A kind of anti-inflammatory anti-acne facial treatment milk, it is related to cosmetic field, the component of the lotion and the parts by weight of each component are as follows: 5.7-12.5 parts of moisturizer, 0.1-0.5 parts of thickener, 6-10 parts of emollients, 0.2-0.7 parts of bacteriostatic agent, 4.1-9.4 parts of acne removing agent, 0.1-0.5 parts of chelating agent, 1.5-3 parts of emulsifier, 0.1-0.3 parts of PH regulator, 0.011-0.15 parts of essential oil, surplus is water.Facial treatment milk in the present invention has the effect of oil-control and anti-acne dual maintenance, it has deep layer regulation water and oil balance, the hair follicle increase cuticula moisture, improve elasticity of skin and Cucumber Extract cell, reduce skin microgroove, inhibiting sebaceous gland activity and B16 cell, promoting collagen synthesis and blood circulation, improve black eye, mildly dispel cutin, opening obstruction, kills Propiobacterium and effective anti-inflammatory anti-oxidant, it is inherently eliminated acne print and skin inflammation, curative effect is short, restore fast, the resistance of skin is had no stimulation and increased to skin.

Description

A kind of anti-inflammatory anti-acne facial treatment milk
Technical field:
The present invention relates to cosmetic fields, and in particular to a kind of anti-inflammatory anti-acne facial treatment milk.
Background technique:
Whelk is medically known as " acne ", is mainly in puberty, therefore is known as " whelk ", it is due to physiology item The factors such as part, living habit and cause.Acne is the common dermatosis chronic disease of the most of youth of both sexes of today's society, is mainly in face Skin, so in physiology and psychologically exert a certain influence and endanger to many youth of both sexes, especially for people seeking beauty, Even more one of scar at heart bottom.In addition, puberty is up to 10 years as long as, the youth of both sexes with whelk are just because of whelk Various harm to people, everyone can have 10 years or so puberty in addition, therefore in the market to the research and development of product for resolving poxes It is growing with production requirement, also becomes people's greater concern instantly about the effect of product for resolving poxes.
In recent years, the type of the cosmetics in terms of anti-acne is multifarious, but anti-acne effect is general, can not be fundamentally Whelk is eradicated, or even since certain acne-eliminating cosmetics contain micro hormone, anti-acne effect is good when initially using, and uses one section It can be recurred after time, the whelk after recurrence is more difficult to treat, and it is normal that the cosmetics containing steroids influence human body Metabolism will cause facial skin and be damaged or become fragile, can not effectively resist the infection of harmful environmental bacterium.Therefore, urgently A anti-inflammatory anti-acne facial treatment milk that can fundamentally treat whelk and be avoided that whelk recurrence need to be researched and developed.
Summary of the invention:
In place of overcoming above-mentioned the shortcomings of the prior art, and provide a kind of anti-inflammatory anti-acne shield Skin lotion.
The technical solution adopted by the present invention are as follows: a kind of anti-inflammatory anti-acne facial treatment milk, the component of the lotion and the weight of each component Measure number are as follows: 5.7-12.5 parts of moisturizer, 0.1-0.5 parts of thickener, 6-10 parts of emollients, 0.2-0.7 parts of bacteriostatic agent, acne removing agent It is 4.1-9.4 parts, 0.1-0.5 parts of chelating agent, 1.5-3 parts of emulsifier, 0.1-0.3 parts of PH regulator, 0.011-0.15 parts of essential oil, remaining Amount is water.The ingredient of bacteriostatic agent is decoyl hydroximic acid, 1,2- pentanediol, propylene glycol, and bacteriostatic agent is directly bought, manufacturer are as follows: Japanese Ai Zhuo company.Ingredient in bacteriostatic agent can also be mixed according to same parts by weight to be configured.The dosage of water can reach To meeting the concentration of entire emulsion formulations subject to the requirement of cosmetics, it is preferred that the dosage of water is 40-60 parts.
Preferably, the parts by weight of the component and each component of the moisturizer are as follows: 2-4 parts of glycerol, 2-4 parts of butanediol, 1-3 parts of dimethyl silicone polymer, 1,2- 0.5-1.0 parts of hexylene glycol, 0.2-0.5 parts of tocopherol.
Preferably, the thickener is selected from xanthan gum, carbomer, scleroglucan glue, Aloe Vera Gel, alginates, maltose Dextrin, guar gum, any one or two or more any mixture in hydroxypropyl guar gum.
Preferably, the parts by weight of the component of the emollients and each component are as follows: 3-5 parts of isononyl isononanoate, octanoic acid/ 3-5 parts of Triglyceride DDD.
Preferably, the chelating agent is selected from parahydroxyacet-ophenone, EDTA, hydroxyethane diphosphonic acid, ethylenediamine tetra-acetic acid One of disodium salt or two or more any mixture.
Preferably, the parts by weight of the component of the acne removing agent and each component are as follows: 3-5 parts of active mixture A, activity 0.5-2 parts of mixture B, 0.5-2 parts of Madagascar Ha Lunjiana extract, 0.1-0.4 parts of allantoin.Active mixture A's Ingredient are as follows: Wild soybean seed extract, houttuynia extract, radix scutellariae root extract, neem leaf extract, Chinese Radix Rehmanniae extract Object, white willow bark extract, Cortex Phellodendri extract, o- cymene -5- alcohol, Bacillus acidi lactici/pear juice tunning filtrate, glycerol Caprylate, Sensiva SC50, PEG-60 rilanit special, hydroxyacetic acid, butanediol, active compound A directly buy the Summer Solstice or the Winter Solstice The naturally vigorous and graceful Co., Ltd of this ball.Ingredient in active compound A can also be mixed according to same parts by weight to be configured. The ingredient of active compound B are as follows: polygonum cuspidate root extract, tea extract, glycyrrhiza glabra root extract, german chamomile flower extract, fan Repeatedly Herba Pelargonii Graveolentis extract, Gotu Kola P.E, active compound B are directly bought to hundred gull Si Te company, South Korea, active compound B Raw material autogamy can be bought, each ingredient is configured according to same ratio.
Preferably, the parts by weight of the component of the emulsifier and each component are as follows: 1-2 parts of emulsifier A, A165 emulsification 0.5-1 parts of agent, 0.1-0.2 parts of sodium bacillus subtilis lipopeptide.The ingredient of emulsifier A are as follows: C12-20 alkyl glucoside, C14-22 alcohol, cream The trade name Montanov L of agent A is directly bought from match BIC Corp, France.The component of A165 emulsifier is glyceryl stearate Acid esters, PEG-100 stearate, the trade name of A165 emulsifier: A165 emulsifier can directly be bought, and be bought big to standing grain Company.
Preferably, the essential oil is selected from the mixture of one or both of Yilan caul-fat, bitter orange flower oil.
Preferably, the parts by weight of the component of the essential oil and each component are 0.01-0.05 parts of Yilan caul-fat, bigarabe flower It is 0.001-0.1 parts oily.
Preferably, the PH regulator is selected from sodium tartrate, sodium salicylate, sodium citrate, triethanolamine, sodium hydroxide In any one, any two kinds or any two or more mixture.
Wild soybean seed extract: claim in archaeophyte ancient books and records herbal for Relief of Famines " hundred careless mirror " Wild soybean seed can hyoscine, function Effect is invigorating the spleen, removing toxic substances promoting eruption, nourishing the liver reason spleen.
Houttuynia extract: acrid flavour, it is cold, it is distributed in lung channel.It can sore be treated in clearing heat and detoxicating, detumescence, promoting urination and removing dampness, heat-clearing stop Dysentery, stomach strengthening and digestion promoting are pulmonary abscess, sore swollen toxin, hemorrhoidal hemorrhage, the retention of heat in the spleen and stomach etc. suffered from real heat, heat toxin, damp evil, disease heat is controlled.It is existing Show that this product has the effects that antibacterial, antiviral, raising immunity of organisms, diuresis for pharmacological evaluation.
Radix scutellariae root extract: primary efficacy is for damp-warm syndrome fever, uncomfortable in chest, feeling thirst but no desire to drink and damp-heat dysentery, jaundice etc. Disease, therefore have effects that heat-clearing and damp-drying drug.
Neem leaf extract: primary efficacy analgesic, desinsection.Control hernia, roundworm, treating swelling and pain by traumatic injury, furunculosis, skin eczema, Impetigo, eczema-like dermatitis, chronic eczema etc..
Chinese glutinous rehmannia root extract: major function: glutinous rehmannia is cool in nature, sweet-bitter flavor there are enriching yin and nourishing kidney, blood-nourishing to enrich blood, cool blood The effect of.All deficiency of Yin deficiency of blood kidney deficiency persons eat it, quite helpful.In addition, glutinous rehmannia has heart tonifying diuresis, antipyretic anti-inflammatory, promotes blood solidifying Gu and reducing the effect of blood glucose.
White willow bark extract: for healing of wound, calm joint and myalgia.It treats small pox and other skins pierces Swash, there is anti-inflammatory effect.
Cortex Phellodendri extract: bitter, it is cold in nature.It is clearing heat and detoxicating, purging intense heat eliminating dampness.Cure mainly acute bacillary dysentery, acute bowel The inflammation such as inflammation, acute icteric hepatitis, urinary system infection contamination.Burning hot wound, tympanitis, acute conjunctivitis etc. are controlled in external application.
Bacillus acidi lactici/pear juice tunning filtrate: rich in sugar, lactic acid and minerals.Primary efficacy can soft and smooth skin, promotion Metabolism improves skin elasticity, moisturizing and reduces wrinkle.It is non-stimulated.
Madagascar's Ha Lunjiana extract: spot is eliminated in confrontation flaw, concealing, and help reduces hoary hair, corrects acne Acne inhibits propionibacterium acnes, and the cell factor with anti-inflammatory effect is able to suppress the function of macrophage and Dendritic Cells Energy.
Gotu Kola P.E: clearing heat and promoting diuresis, subdhing swelling and detoxicating control acute diseases such as cholera and sunstroke xenon abdominal pain, heat rushes down, the leaching of dysentery, jaundice with damp-heat pathogen, sand, blood Leaching, haematemesis, hemoptysis, hot eyes, larynx swollen, rubeola, scabies, malignant boil carbuncle swells poison, traumatic injury etc..Once there is report 0.25- containing centella Skin disease is treated in the creams agent of 1% alcohol extracting thing, obtains good result.
Polygonum cuspidate root extract: there is removing dampness through diuresis and removing jaundice, clearing heat and detoxicating, removing blood stasis and acesodyne, relieving cough and reducing sputum effect.For damp and hot Huang Subcutaneous ulcer, stranguria with turbid discharge, leukorrhagia, rheumatic arthralgia, carbuncle sore tumefacting virus, scald, menostasis, abdominal mass, instep beat damage, cough with lung heat.
Tea extract: primary efficacy, anti-oxidant, anti-aging, fat reducing, weight-reducing prevent UV radiation and sun-proof, antibacterial, Anti-inflammatory, deodorization promote wound healing.
Glycyrrhiza glabra root extract: root, the rhizomes histocyte of glycyrrhiza glabra are interior, and there is the very strong skins of antioxygenic activity Skin decoloration, the functional component lightened the stain, and be main component, i.e., glycyrrhiza glabra element and glycyrrhiza glabra are fixed.There is " whitening gold " Title.Have the function of the very strong depigmentation of skin of antioxygenic activity, lighten the stain, be used for whitening, sterilization is lightened the stain, also be can be used Make fragrance, and has the effect for skin of releiving.
German chamomile flower extract: Flos Chrysanthemi, i.e. chamomile, containing volatile oil, flavone compound, amino acid, chlorogenic acid and Microelement etc..There is the bioactivity such as antibacterial, anti-oxidant, anti-inflammatory, antiallergic of releiving, being widely used in based on chrysanthemum extract In cosmetic, pre- hypo-allergenic, moisturizing, prevention and treatment acne and anti-aging and other effects can be played.
Rosemary leaf extract: Rosemary Oil fragrance is pure and fresh, has sterilization, desinsection, anti-inflammatory isoreactivity, has stronger Astriction improves greasy unclean skin,
Tocopherol (vitamin E): it is liposoluble vitamin, is known as blood vessel scavenger.It has prevention cardiovascular disease Remarkable result, and have very strong antioxidation.Adult diseases can not only be prevented, delay cellular oxidation aging, moisturize the skin, disappear Except color spot, the looks that retain youth.
Yilan caul-fat: can be used as antibacterial agent, have facilitation, protein lyase and mRNA phase to protein cleavage enzymatic activity It closes, the hydratability of cortex can be improved.
Bitter orange flower oil: effect just on the skin, enhances cell viability, helps cytothesis, increases skin elasticity;Whitening, Moisturizing, light spot, nourishing is crease-resistant, restores delicate, is suitble to stemness, sensitivity and other problems skin, and especially spiral helicine vein is bent , scar and striae of pregnancy;When according to X-ray, it is also used to protection skin.
Isononyl isononanoate is used as emollients use in the present invention, keeps the facial treatment milk in the present invention more easy to apply, has Dry and comfortable and extremely soft feel, is splendid emollients.
Anti-inflammatory anti-acne facial treatment milk in the present invention, in 100,000 clean level workshops, is weighed according to certain weight ratio Raw material investment emulsifying device is stated, is emulsified, after detecting qualification after emulsification, discharging is eventually fabricated the product of qualified.
The invention has the benefit that the facial treatment milk in the present invention has the effect of oil-control and anti-acne dual maintenance, it With deep layer regulation water and oil balance, increase cuticula moisture, improve elasticity of skin and Cucumber Extract cell, reduce skin microgroove, Inhibit sebaceous gland activity and B16 cell, promotes collagen synthesis and blood circulation, improve black eye, mildly dispel angle Matter, the hair follicle for opening obstruction, killing Propiobacterium are simultaneously effective anti-inflammatory anti-oxidant, are inherently eliminated acne print and skin inflammation, Curative effect is short, restores fast, the resistance of skin is had no stimulation and increased to skin.In addition, the facial treatment milk in the present invention can The inhibition cyclo-oxygenase (COX) of selectivity, COX can produce arachidonic acid from impaired cell membrane, have COX1 and COX2, wherein COX2 is the principal element for causing inflammation, and this extract is also prevented from the expression of the TRL2 as caused by stress, Immune disorder caused by so as to relieve stress, and it is able to suppress histamine release of mast cell, avoid chafing cause from itching.
Specific embodiment:
Invention is further explained in conjunction with specific embodiments:
Embodiment one:
A kind of anti-inflammatory anti-acne facial treatment milk, the component of the lotion and the parts by weight of each component are as follows: isononyl isononanoate 3 Part, 3 parts of active mixture A, 3 parts of caprylic/capric triglyceride, 2 parts of glycerol, 2 parts of butanediol, Madagascar Ha Lunjiana 0.5 part of extract, 1 part of dimethyl silicone polymer, 1 part of emulsifier A, 0.5 part of A165 emulsifier, 0.5 part of active mixture B, 0.5 part of 1,2- hexylene glycol, 0.2 part of antibacterial agent, 0.2 part of tocopherol (vitamin E), 0.1 part of allantoin, parahydroxyacet-ophenone 0.1 Part, 0.1 part of triethanolamine, 0.1 part of xanthan gum, 0.01 part of Yilan caul-fat, 0.001 part of bitter orange flower oil, remainder are pure water.
Embodiment two:
A kind of anti-inflammatory anti-acne facial treatment milk, the component of the lotion and the parts by weight of each component are as follows: isononyl isononanoate 4 Part, 4 parts of active mixture A, 4 parts of caprylic/capric triglyceride, 3 parts of glycerol, 3 parts of butanediol, Madagascar Ha Lunjiana 1.2 parts of extract, 2 parts of dimethyl silicone polymer, A1.5 parts of emulsifier, 0.8 part of A165 emulsifier, B1.1 parts of active mixture, 0.8 part of 1,2- hexylene glycol, 0.5 part of antibacterial agent, 0.3 part of tocopherol (vitamin E), 0.2 part of allantoin, parahydroxyacet-ophenone 0.3 Part, 0.2 part of triethanolamine, 0.3 part of xanthan gum, 0.03 part of Yilan caul-fat, 0.05 part of bitter orange flower oil, remainder are pure water.
Embodiment three:
A kind of anti-inflammatory anti-acne facial treatment milk, the component of the lotion and the parts by weight of each component are as follows: isononyl isononanoate 5 Part, A5 parts of active mixture, 5 parts of caprylic/capric triglyceride, 4 parts of glycerol, 4 parts of butanediol, Madagascar Ha Lunjiana are mentioned Take 2 parts of object, 3 parts of dimethyl silicone polymer, A2 parts of emulsifier, 1 part of A165 emulsifier, B2 parts of active mixture, 1,2- hexylene glycol 1.0 parts, 0.7 part of antibacterial agent, 0.5 part of tocopherol (vitamin E), 0.4 part of allantoin, 0.5 part of parahydroxyacet-ophenone, triethanolamine 0.3 part, 0.5 part of xanthan gum, 0.05 part of Yilan caul-fat, 0.1 part of bitter orange flower oil, it is remaining be pure water.
(1) moistening effect is tested:
20-35 years old 120 volunteers are selected, men and women is fifty-fifty, and all volunteer's exclusion conditions meet " cosmetics contact Dermatitis diagnostic criteria and treatment principle ", 120 volunteers are randomly divided into 4 groups, every group of 30 people, every group of men and women is fifty-fifty, random to select Take one group to use commercially available same type facial treatment milk product as a control group, in addition three groups use in the present invention respectively embodiment one to Facial treatment milk in embodiment three, in test, specific experimental method is as follows: study subject is used to carry out with a facial cleanser After cleaning facial skin, face's droplet is dried using the dry towel after disinfection, cleans both hands, with finger by the shield of 1.5g test Skin lotion is uniformly applied on facial skin, gently pat until facial treatment milk be coated uniformly on facial skin and be absorbed, survey It tries in the period, carries out the acquisition of four data altogether, respectively using the data before product, after product one week, two weeks and four weeks Data acquisition, specific environment of testing is 20 DEG C, relative humidity 63%.Test is respectively adopted skin moisture content test and visits Head (Corneometer CM825 probe), German CK company production;Skin water loss test probe (Tewameter TM300), German CK company production;Each volunteer's skin moisture content MMV value, skin transepidermal water loss TEWL value are measured respectively And the rear self-assessment of volunteer.Specific test result see the table below:
Test group Before use It uses one week It uses two weeks Use surrounding
Embodiment one 36.12 67.57 70.90 77.21
Embodiment two 36.47 67.84 70.83 78.31
Embodiment three 36.33 67.54 71.10 78.50
Control group 36.25 43.12 51.99 58.47
Moisture value is bigger, illustrates that moisture content is higher, and divides water change rate i.e. hydration rate higher, then illustrates that moisturizing effect is got over It is good.As can be seen from the above table, compared with the control group, facial treatment milk of the embodiment one into embodiment three has skin outstanding Moistening effect, moisture preserving time is long, and more sufficient moisture can be provided for skin.Wherein the facial treatment milk in embodiment three has excellent Moistening effect in embodiment one and embodiment two.
Skin barrier repairing effect can scatter and disappear TEWL Value Data from moisture of skin to embody, and TEWL value is smaller, water dispersion Mistake is fewer, conversely, TEWL value is bigger, moisture loss is more, and specific test result is as follows:
Test group Before use It uses one week It uses two weeks Use surrounding
Embodiment one 36.58 30.23 28.71 27.96
Embodiment two 36.54 30.17 28.47 27.84
Embodiment three 36.51 30.24 28.39 27.98
Control group 36.55 34.96 33.40 32.71
As can be seen from the above table, TEWL value of the comparing of TEWL value of the present embodiment one into embodiment three according to group It is small, it was demonstrated that the present embodiment one has the skin barrier repairing effect better than commercial like product into embodiment three.
During using the facial treatment milk product in the present invention, subject is according to individual first week of test period, the Trial state and every organoleptic conditions after two weeks and 4th week carry out subjective assessment.Specific evaluation result see the table below:
(2) product appearance and pH value test
Observe embodiment one to embodiment three facial treatment milk appearance, and smelling its smell, record product appearance and production Product smell.When carrying out pH value test, weigh 1 part of sample (being accurate to 0.1g), add it is 10 parts of deionized water not carbonated, 40 DEG C are heated to, and is stirred continuously to lotion and is uniformly dissolved, is cooled to room temperature, as solution to be measured.It is examined using PH value detector It surveys the pH value of solution and records pH value.
As can be seen from the above table, appearance, smell and the pH value of facial treatment milk of the embodiment one into embodiment three meet The requirement of cosmetics.
(3) product viscosity is tested
Viscosity of the embodiment of the present invention one into embodiment three can be used rotational viscometer and measure, and be turned using No. 4 Son is measured at 6rpm.Viscosity equal 15000-20000mpa.s of the embodiment one of survey into embodiment three, meeting The range of viscosities that cosmetic requires.
(4) anti-acne effect is tested:
Facial treatment milk in this test through the invention tests the inhibiting effect of propionibacterium acnes its anti-acne effect, The specific test method is as follows: product 1g of each Example one into embodiment three be separately added into three it is configured in advance 106In the suspension of cfu/mL propionibacterium acnes, suspension configuration is using the propionibacterium acnes culture that will be cultivated for 24 hours It is washed down with 0.03mol/LPBS, bacterium solution suspension is made, facial treatment milk is mixed with the concussion of bacterium colony suspension, starts timing, After 20min, 9mL0.03mol/L PBS is added and mixes well, after making appropriate dilution, 1mL is taken to be placed in two parallel plates respectively In, it adds corresponding culture medium and is cultivated respectively, do bacterium colony counting, the above test in triplicate, is averaged, sets simultaneously The PBS solution of 0.1g is only added in blank control, blank control.Calculate: C=(A-B)/A*100%, in formula: C is bacteriostasis rate, %; A: control sample averagely recycles bacterium colony;B: test specimen averagely recycles bacterium colony.The bacteriostasis rate of embodiment one to embodiment three exists Between 90%-95%.Therefore, the facial treatment milk that the present embodiment one is prepared into embodiment three has very propionibacterium acnes Strong bacteriostasis rate can prevent propionibacterium acnes hyperplasia, eliminate whelk from the root to realize, while avoiding whelk Recurrence.
(5) specifically used case:
Facial treatment milk in the present invention first coats toner or stoste, then take suitable in use, cleaning face first after cleaning Lotion in the amount present invention is uniformly applied to face in the centre of the palm, is gently massaged into absorption and uses 2 to 3 times daily.
Case one:
Lee, male, 25 years old, skin quality was oily skin, often emits acne on the face, coated the facial treatment milk product in the present invention Afterwards, just have within second day and significantly move back red detumescence, continue to use, twice daily smear facial treatment milk product of the present invention, one bottle of use After complete, normal skin quality is converted into Oily, small pox has disappeared.
Case two:
Cao, female, 18 years old, small pox was serious on the face, coated facial treatment milk product of the present invention second day, silent disappearance, sensitive Skin become to stablize skin quality, be almost recovered after 15 days, only remain a little light acne print.
In conclusion the facial treatment milk in the present invention has the effect of oil-control and anti-acne dual maintenance, it has deep layer tune Water and oil balance is controlled, increases cuticula moisture, improve elasticity of skin and Cucumber Extract cell, reduction skin microgroove, inhibition sebaceous glands Activity and B16 cell promote collagen synthesis and blood circulation, improve black eye, mildly dispel cutin, open obstruction Hair follicle, kill Propiobacterium and effective anti-inflammatory anti-oxidant, be inherently eliminated acne print and skin inflammation, curative effect is short, restores Fastly, the resistance of skin is had no stimulation and increased to skin.In addition, the facial treatment milk in the present invention is capable of the inhibition of selectivity Cyclo-oxygenase (COX), COX can produce arachidonic acid from impaired cell membrane, there is COX1 and COX2, and wherein COX2 is Cause the principal element of inflammation, this extract is also prevented from the expression of the TRL2 as caused by stress, so as to alleviate pressure Immune disorder caused by power, and it is able to suppress histamine release of mast cell, avoid chafing cause from itching.
For those skilled in the art, it is various corresponding that other can be made according to above technical scheme and design Change and deformation, and all these change and modification all should belong within the scope of protection of the claims of the present invention.

Claims (10)

1. a kind of anti-inflammatory anti-acne facial treatment milk, it is characterised in that: the component of the lotion and the parts by weight of each component are as follows: moisturizer 5.7-12.5 parts, 0.1-0.5 parts of thickener, 6-10 parts of emollients, 0.2-0.7 parts of bacteriostatic agent, 4.1-9.4 parts of acne removing agent, chelating 0.1-0.5 parts of agent, 1.5-3 parts of emulsifier, 0.1-0.3 parts of PH regulator, 0.011-0.15 parts of essential oil, surplus is water.
2. anti-inflammatory anti-acne facial treatment milk according to claim 1, it is characterised in that: the component and each group of the moisturizer The parts by weight of part are as follows: 2-4 parts of glycerol, 2-4 parts of butanediol, 1-3 parts of dimethyl silicone polymer, 1,2- 0.5-1.0 parts of hexylene glycol, 0.2-0.5 parts of tocopherol.
3. anti-inflammatory anti-acne facial treatment milk according to claim 1, it is characterised in that: the thickener be selected from xanthan gum, It is carbomer, scleroglucan glue, Aloe Vera Gel, alginates, maltodextrin, guar gum, any one in hydroxypropyl guar gum Kind or two or more any mixture.
4. anti-inflammatory anti-acne facial treatment milk according to claim 1, it is characterised in that: the component and each group of the emollients The parts by weight of part are as follows: 3-5 parts of isononyl isononanoate, 3-5 parts of caprylic/capric triglyceride.
5. anti-inflammatory anti-acne facial treatment milk according to claim 1, it is characterised in that: the chelating agent is selected from para hydroxybenzene One of ethyl ketone, EDTA, hydroxyethane diphosphonic acid, disodium EDTA or two or more any mixing Object.
6. anti-inflammatory anti-acne facial treatment milk according to claim 1, it is characterised in that: the component and each group of the acne removing agent The parts by weight of part are as follows: 3-5 parts of active mixture A, 0.5-2 parts of active mixture B, Madagascar's Ha Lunjiana extract 0.5-2 parts, 0.1-0.4 parts of allantoin.
7. anti-inflammatory anti-acne facial treatment milk according to claim 1, it is characterised in that: the component and each group of the emulsifier The parts by weight of part are as follows: 1-2 parts of emulsifier A, 0.5-1 parts of A165 emulsifier, 0.1-0.2 parts of sodium bacillus subtilis lipopeptide.
8. anti-inflammatory anti-acne facial treatment milk according to claim 1, it is characterised in that: the essential oil be selected from Yilan caul-fat, The mixture of one or both of bitter orange flower oil.
9. anti-inflammatory anti-acne facial treatment milk according to claim 1, it is characterised in that: the component and each component of the essential oil Parts by weight be 0.01-0.05 parts of Yilan caul-fat, 0.001-0.1 parts of bitter orange flower oil.
10. anti-inflammatory anti-acne facial treatment milk according to claim 1, it is characterised in that: the PH regulator is selected from winestone Sour sodium, sodium salicylate, sodium citrate, triethanolamine, in sodium hydroxide any one, it is two kinds or any two or more any Mixture.
CN201910490632.3A 2019-06-06 2019-06-06 A kind of anti-inflammatory anti-acne facial treatment milk Pending CN110101587A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201910490632.3A CN110101587A (en) 2019-06-06 2019-06-06 A kind of anti-inflammatory anti-acne facial treatment milk

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201910490632.3A CN110101587A (en) 2019-06-06 2019-06-06 A kind of anti-inflammatory anti-acne facial treatment milk

Publications (1)

Publication Number Publication Date
CN110101587A true CN110101587A (en) 2019-08-09

Family

ID=67494153

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201910490632.3A Pending CN110101587A (en) 2019-06-06 2019-06-06 A kind of anti-inflammatory anti-acne facial treatment milk

Country Status (1)

Country Link
CN (1) CN110101587A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110893151A (en) * 2019-12-20 2020-03-20 广州市拉凯尔干细胞研究所 Preparation method of phase-D emulsified cream with anti-inflammatory effect
CN115105453A (en) * 2021-08-19 2022-09-27 上海绍能信息科技有限公司 Skin care product with antibacterial, anti-inflammatory and repairing functions and preparation method thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105748353A (en) * 2016-03-09 2016-07-13 广州千百度化妆品有限公司 Cosmetic composition with acne treatment function and preparation method thereof
CN109330959A (en) * 2018-11-30 2019-02-15 广东盛美化妆品有限公司 A kind of anti-acne maintenance stoste and preparation method thereof containing Katsumadai seed extract

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105748353A (en) * 2016-03-09 2016-07-13 广州千百度化妆品有限公司 Cosmetic composition with acne treatment function and preparation method thereof
CN109330959A (en) * 2018-11-30 2019-02-15 广东盛美化妆品有限公司 A kind of anti-acne maintenance stoste and preparation method thereof containing Katsumadai seed extract

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
广州市裕朝化妆品有限公司: "《http://ftba.nmpa.gov.cn:8181/ftban/itownet/hzp_ba/fw/pz.jsp?processid=201904091019455tuuv&nid=201904091019455tuuv》", 22 April 2019, 国产非特殊用途化妆品备案信息服务平台 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110893151A (en) * 2019-12-20 2020-03-20 广州市拉凯尔干细胞研究所 Preparation method of phase-D emulsified cream with anti-inflammatory effect
CN115105453A (en) * 2021-08-19 2022-09-27 上海绍能信息科技有限公司 Skin care product with antibacterial, anti-inflammatory and repairing functions and preparation method thereof

Similar Documents

Publication Publication Date Title
CN111249209B (en) Moisturizing repair cream and preparation method thereof
CN105769698B (en) A kind of cosmetic composition and its application without preservative
CN103237555B (en) Topical skin care formulation
CN111202695A (en) Natural edible composition with health care function, application thereof, makeup cosmetic and preparation method thereof
CN108670943A (en) A kind of moisturizing, whitening, light spot composition of plant extracts
CN109288764B (en) Hydrolat spray and preparation method thereof
CN106176259B (en) Sunscreen cream with double isolation and after-sun repair effects
CN109662928A (en) A kind of skin care compositions and its application and preparation method with sun-proof reparation effect
CN109453087B (en) Whitening skin-penetrating lotion, preparation method thereof and whitening cosmetic additive
CN105030621A (en) Moisturizing and acne removing toner and preparing method thereof
CN109453059B (en) Whitening cosmetic additive, whitening sleep mask and preparation method of whitening cosmetic additive
CN109431912A (en) Skin oil balancing composition and application thereof
KR20080053614A (en) Composition comprising lava seawater salt
KR20090130584A (en) Cosmetic composition comprising an extract of mixed herbs having skin whitening and wrinkle improving activity
KR100357824B1 (en) Cosmetic compounds containing natural products for treating and preventing acne
KR101474340B1 (en) Anti-aging cosmetic composition comprising herb ferment extract
CN110101587A (en) A kind of anti-inflammatory anti-acne facial treatment milk
TW201200032A (en) Hyaluronic acid production promoting agent
CN105998617A (en) Externally applied traditional Chinese medicine extract with effect of soothing senile pruritus, as well as preparation method and application thereof
KR102443283B1 (en) Cosmetic composition with excellent skin barrier using skin microbiome
JP4703832B2 (en) Collagen production promoter, estrogen-like agent, collagenase inhibitor, skin cosmetic and food and drink
KR101252560B1 (en) Cosmetic composition containing extracts of Impatiens balsamina L. for controlling anti-acne or anti-comedone
KR101459742B1 (en) Cosmetic composition for improving acne containing extracts of natural substance
KR20200108207A (en) A method for extracting fat soluble solvent of Loquat leaf (Eriobotrya japonica Lindley) and Taraxaci Herba(Taraxacum platycarpum) for use as a cosmetic composition
KR102051417B1 (en) The cosmetic composition for the prevention and improvement of striae distensae

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication
RJ01 Rejection of invention patent application after publication

Application publication date: 20190809