CN107361243A - A kind of feed addictive for promoting cold water fish growth and application thereof - Google Patents

A kind of feed addictive for promoting cold water fish growth and application thereof Download PDF

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Publication number
CN107361243A
CN107361243A CN201710596275.XA CN201710596275A CN107361243A CN 107361243 A CN107361243 A CN 107361243A CN 201710596275 A CN201710596275 A CN 201710596275A CN 107361243 A CN107361243 A CN 107361243A
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parts
cold water
water fish
feed addictive
feed
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CN201710596275.XA
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乔淑芬
刘桓君
王日昕
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Tonghua Normal University
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Tonghua Normal University
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K50/00Feeding-stuffs specially adapted for particular animals
    • A23K50/80Feeding-stuffs specially adapted for particular animals for aquatic animals, e.g. fish, crustaceans or molluscs
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/20Animal feeding-stuffs from material of animal origin
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/30Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/174Vitamins
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/80Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in fisheries management
    • Y02A40/81Aquaculture, e.g. of fish
    • Y02A40/818Alternative feeds for fish, e.g. in aquacultures
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P60/00Technologies relating to agriculture, livestock or agroalimentary industries
    • Y02P60/80Food processing, e.g. use of renewable energies or variable speed drives in handling, conveying or stacking
    • Y02P60/87Re-use of by-products of food processing for fodder production

Abstract

The invention discloses a kind of feed addictive for promoting cold water fish growth and application thereof, the composition and its parts by weight of the additive are:17 22 parts of folium isatidis, 16 22 parts of cortex acanthopanacis, 11 15 parts of Verbena officinalis, 24 parts of dried orange peel, 7 10 parts of radix scutellariae, 57 parts of cape jasmine, 58 parts of mountain naphthalene, 35 parts of Radix Codonopsis, 12 parts of garlic, 0.2 0.5 parts of vitamin C, 0.3 0.6 parts of honey.Have the beneficial effect that:The additive of the present invention has attractant, can increase cold water fish food ration, improves growth rate, promotes growth;The additive can strengthen digestive enzyme activity, regulation intestinal microflora, improve the growth performance of cold water fish;The addictive preparation method is simple, can improve the utilization rate of raw material, and immune response of the body to extraneous pathogen can be strengthened by being added in feed, strengthens the immunity and premunition of cold water fish, reduces the cultivation death rate.

Description

A kind of feed addictive for promoting cold water fish growth and application thereof
Technical field
The present invention relates to aquaculture feeds additive processing technique field, promotes what cold water fish grew more particularly to a kind of Feed addictive and application thereof.
Background technology
Cold water fish is a species for fish, mainly people according to requirement of the fish for living environment, especially water temperature, In aquaculture, water temperature is referred to as cold water fishes by people's custom higher than 20 DEG C of fish that cannot be survived, that is, is commonly called as " cold water fish ", such as brave Jiayu, schizothoracin.The protein content of cold water fish is higher than the protein content of in general fish, cholesterol Content is very low, and meat taste more preferably, contains abundant amino acid, unrighted acid;DHA, EPA referred to as docosapentaenoic acid contain Amount is higher than other fish several times, so nutritive value is higher than in general fish.Gradually stepped up with the living standard of people, the public To the degree of recognition more and more higher of cold water fish, but general cold water fish is slow-growing, and the normality that supply falls short of demand is always presented in market, because This antibiotic and growth accelerator have extensive use.But national safety and environmental consciousness steps up, the public is to water The quality of product is increasingly paid close attention to, and people are also increasingly paid close attention to the security of food.Therefore green production is carried out As the developing direction of current aquaculture.Chinese herbal and crude drugs preparations is exactly a kind of green feed additive with bright prospects, it It is small or without the characteristic such as the resistance to the action of a drug and basic noresidue poisonous substance with natural, efficient, the resistance to the action of a drug.Fish production is put into practice and also demonstrated that, in As mixed feeding agent or feed addictive while aquatic livestock production performance and feed efficiency is improved, and can fully ensures that herbal medicine The health of human body, have the double action of the property of medicine and trophism concurrently, be that traditional chemical synthesis feed addictive is incomparable, especially It is applied to intensive, large-scale production the needs of current culture fishery.Therefore, with the addition of Chinese herbal medicine substitute antibiotics Agent will have been to be concerned by more and more people, and its application prospect also can be more extensive.
Prior art such as Authorization Notice No. is the B of CN 102845648 Chinese invention patent, discloses and promotes prawn growth Chinese herbal feed additive, it by following weight match raw material be made:Root of bidentate achyranthes 2-3 parts, Radix Rhapontici seu Radix Echinopsis 2-3 parts, Radix Isatidis 2-3 Part, bark of eucommia 2-4 parts, rheum officinale 0.5-1 parts, Echinacea 3-4 parts, Poria cocos 3-4 parts, radix glycyrrhizae 1-2 parts.The raw material sources of the additive are wide It is general, cheap, simple production process, for prawn culturing, growth, controlling disease can be effectively facilitated, and it is easy to use, into This cheap, safe without toxic side effect.But the feed addictive simply carries out raw material simple mixing and crushing, fails handle The active ingredient of each raw material discharges.
The content of the invention
It is an object of the invention to provide a kind of raw material sources are wide, environment protection health, Chinese herbal medicine active component purity is high, food calling Effect is good, improves the digestibility and utilization rate of feed, strengthens body anti-immunity power and premunition, improves cold water fish growth rate, Reach the purpose for promoting growth, preparation method is simple, feed addictive for promoting cold water fish growth easy to use and application thereof.
The present invention is directed to the problem of being mentioned in above-mentioned technology, and the technical scheme taken is:It is a kind of to promote what cold water fish grew Feed addictive, composition and its parts by weight are:Folium isatidis 17-22 parts, cortex acanthopanacis 16-22 parts, Verbena officinalis 11-15 parts, dried orange peel 2-4 Part, radix scutellariae 7-10 parts, cape jasmine 5-7 parts, mountain naphthalene 5-8 parts, Radix Codonopsis 3-5 parts, garlic 1-2 parts, vitamin C 0.2-0.5 parts, honey 0.3-0.6 parts.Above-mentioned additive can give out a kind of unique taste in water body, and induction cold water fish is ingested to feed, increased Add food ration, improve cold water fish growth rate, reach the purpose for promoting growth;Additive contains a variety of biological effective components, energy Strengthen digestive enzyme activity, regulation intestinal microflora, suppress the breeding of pernicious bacteria, improve feed nutrient absorptivity and Conversion ratio, so as to effectively improve the growth performance of cold water fish;Immune response of the body to extraneous pathogen can be strengthened, strengthen cold water The immunity and premunition of fish, be advantageous to the growth of cold water fish, reduce the cultivation death rate.
A kind of preparation method for the feed addictive for promoting cold water fish to grow, specifically includes following steps:
Pretreatment of raw material:Folium isatidis, cortex acanthopanacis, Verbena officinalis, dried orange peel, radix scutellariae, cape jasmine, mountain naphthalene, Radix Codonopsis, garlic are measured by formula, Just crushed after low temperature is continuous drying, then ultramicro grinding to 500-700 mesh, produces medicinal powder, standby, the continuous drying technique energy of low temperature The volatility of active ingredient in Chinese herbal medicine is enough reduced, reduces loss, certain fineness can be provided for ultramicro grinding by just crushing Raw material, make ultramicro grinding be more prone to carry out, improve the operating efficiency of ultramicro grinding, reduce energy consumption, save energy consumption and Cost, ultramicro grinding can destroy Chinese herbal medicine cell membrane, intracellular effective drug ingedient is fully exposed, improve medicine The bioavailability of thing, the dosage for reducing medicine, and the uniformity of particle is improved to a certain extent, make feed addictive It is easier to be dispersed in feed;
Ionic liquid assisted extraction:By in medicinal powder by weight:Volume=1:6-8 adds vacuum drying 22-26h liquid chlorination 1- Butyl -3- methylimidazole ionic liquids, add active peptides, and the weight ratio of medicinal powder and active peptides is 1:0.002-0.004, Then 4-6h is stirred at 65-75 DEG C, mixed liquor is cooled to room temperature, and the weight of water, medicinal powder and water then will be added in mixed liquor Than for 1:12-15,5-10min is continuously stirred, filter, produce extract solution, the amino acid sequence of above-mentioned active peptides is TDHKLCVCVNCFCCGAAKCYPFKYGVAGFYTHCGPNFCCCIS, the active peptides can deploy parallel under charge effect It is arranged in cell membrane surface or forms a thing, changes the surface tension of cell membrane, shape using hydrophobic effect and molecular tension effect Cause membrane damage into transmembrane potential difference, the active drug composition quick release for making medicinal powder intracellular comes out, the step intermediate ion Liquid can dissolve the cell membrane of medicinal powder, it is possible to increase the permeability of cell membrane so as to improve the recovery rate of active ingredient in Chinese herbal medicine, The release of active ingredient and recovery rate in medicinal powder can be assisted to improve significantly, and the active ingredient extracted is easier to hydrolyze, the extraction Liquid is mainly polysaccharide, glucoside, alkaloid, organic acid, terpene and alcohols etc., and there is apparent sterilizing to act on, can be effective The resistance against diseases of cold water fish is improved, especially has improvement result to slow-growing fish, moreover it is possible to which fattening is got fat;Wherein medicinal ingredient energy Enriching the blood and tonifying qi, good efficacy to suffering from a deficiency of the kidney, promotion is digested and assimilated and enhancing development;
It is prepared by additive:Formula ratio vitamin C and honey will be added in extract solution, then dried, produced and promote cold water fish growth Feed addictive, the additive can give out a kind of unique taste in water body, and induction cold water fish is ingested to feed, is increased Add food ration, improve cold water fish growth rate, reach the purpose for promoting growth;Additive contains a variety of biological effective components, energy Strengthen digestive enzyme activity, regulation intestinal microflora, suppress the breeding of pernicious bacteria, so as to effectively improve the growth of cold water fish Energy;The amino acid content in the muscle of cold water fish can be promoted to change, protein content in muscle can be significantly improved, reduce fat Content, wherein the amino acid content with Titian function of odor has obvious rising, so as to reach the function of improving cold water meat quality of fish;Energy Strengthen immune response of the body to extraneous pathogen, strengthen the immunity and premunition of cold water fish, reduce the cultivation death rate.
A kind of purposes for the feed addictive for promoting cold water fish to grow:The feed addictive directly addition is entered in feed Row is fed, and addition is the 1-2% of feed relative, and the addition of feed addictive make it that the feed phagostimulating effect is good, the energy in water body A kind of unique taste is given out, induction cold water fish is ingested to feed, is increased food ration, is improved cold water fish growth rate, promotees Enter its growth;The utilization rate and high conversion rate of the feed, so as to effectively improve the growth performance of cold water fish, cold water can be significantly improved The function of meat quality of fish;Immune response of the body to extraneous pathogen can be strengthened, strengthen the immunity and premunition of cold water fish, reduced The death rate is cultivated, increases breeding income.
Compared with prior art, the advantage of the invention is that:1)The additive of the present invention can give out one kind in water body Unique taste, induction cold water fish are ingested to feed, are increased food ration, are improved cold water fish growth rate, reach promotion growth Purpose;2)The additive contains a variety of biological effective components, can strengthen digestive enzyme activity, regulation intestinal microflora, suppress The breeding of pernicious bacteria, so as to effectively improve the growth performance of cold water fish;3)The additive can promote in the muscle of cold water fish Amino acid content changes, and can significantly improve protein content in muscle, fat content is reduced, wherein with Titian function of odor Amino acid content has obvious rising, so as to reach the function of improving cold water meat quality of fish;4)The addictive preparation method is simple, can carry The utilization rate of high raw material, immune response of the body to extraneous pathogen can be strengthened by being added in feed, strengthen the immune of cold water fish Power and premunition, reduce the cultivation death rate.
Specific embodiment
The present invention program is described further below by embodiment:
Embodiment 1:
A kind of feed addictive for promoting cold water fish growth, composition and its parts by weight are:20 parts of folium isatidis, 19 parts of cortex acanthopanacis, horse 13 parts of whip grass, 3 parts of dried orange peel, 8 parts of radix scutellariae, 6 parts of cape jasmine, 7 parts of mountain naphthalene, 4 parts of Radix Codonopsis, 1.5 parts of garlic, 0.4 part of vitamin C, honey 0.4 part.Above-mentioned additive can give out a kind of unique taste in water body, and induction cold water fish is ingested to feed, and increase is taken the photograph Appetite, cold water fish growth rate is improved, reach the purpose for promoting growth;Additive contains a variety of biological effective components, can strengthen Digestive enzyme activity, regulation intestinal microflora, suppress the breeding of pernicious bacteria, improve absorptivity and the conversion of feed nutrient Rate, so as to effectively improve the growth performance of cold water fish;Immune response of the body to extraneous pathogen can be strengthened, strengthen cold water fish Immunity and premunition, be advantageous to the growth of cold water fish, reduce the cultivation death rate.
A kind of preparation method for the feed addictive for promoting cold water fish to grow, specifically includes following steps:
1)Pretreatment of raw material:Folium isatidis, cortex acanthopanacis, Verbena officinalis, dried orange peel, radix scutellariae, cape jasmine, mountain naphthalene, Radix Codonopsis, big is measured by formula Garlic, the continuous drying 3.5h of low temperature under conditions of 55 DEG C, 75 mesh just are crushed in mechanical crusher is put into, then ultramicro grinding To 600 mesh, medicinal powder is produced, standby, the continuous drying technique of low temperature can reduce the volatility of active ingredient in Chinese herbal medicine, reduce damage Lose, the raw material of certain fineness can be provided for ultramicro grinding by just crushing, makes ultramicro grinding be more prone to carry out, improves ultra micro The operating efficiency of crushing, energy consumption is reduced, Chinese herbal medicine cell membrane can be destroyed by saving energy consumption and cost, ultramicro grinding, be made thin The effective drug ingedient of intracellular is fully exposed, and improves the bioavailability of medicine, reduces the dosage of medicine, and one Determine to improve the uniformity of particle in degree, make feed addictive be easier to be dispersed in feed;
2)Ionic liquid assisted extraction:By in medicinal powder by weight:Volume=1:7 add vacuum drying 24h liquid chlorination 1- fourths Base -3- methylimidazole ionic liquids, add active peptides, and the weight ratio of medicinal powder and active peptides is 1:0.003, then in oil Continuous mechanical agitation 5h under conditions of 70 DEG C of bath, it is ensured that the solubility of medicinal powder reaches maximum, mixed liquor is cooled into room temperature, then Water will be added in mixed liquor, the weight ratio of medicinal powder and water is 1:14, continuous mechanical agitation 7min at room temperature, through cake filtration, i.e., Extract solution is obtained, the amino acid sequence of above-mentioned active peptides is TDHKLCVCVNCFCCGAAKCYPFKYGVAGFYTHCGPNFCCCIS, the active peptides can deploy parallel under charge effect It is arranged in cell membrane surface or forms a thing, changes the surface tension of cell membrane, shape using hydrophobic effect and molecular tension effect Cause membrane damage into transmembrane potential difference, the active drug composition quick release for making medicinal powder intracellular comes out, the step intermediate ion Liquid can dissolve the cell membrane of medicinal powder, it is possible to increase the permeability of cell membrane so as to improve the recovery rate of active ingredient in Chinese herbal medicine, The release of active ingredient and recovery rate in medicinal powder can be assisted to improve significantly, and the active ingredient extracted is easier to hydrolyze, the extraction Liquid is mainly polysaccharide, glucoside, alkaloid, organic acid, terpene and alcohols etc., and there is apparent sterilizing to act on, can be effective The resistance against diseases of cold water fish is improved, especially has improvement result to slow-growing fish, moreover it is possible to which fattening is got fat;Wherein medicinal ingredient energy Enriching the blood and tonifying qi, good efficacy to suffering from a deficiency of the kidney, promotion is digested and assimilated and enhancing development;
3)It is prepared by additive:Formula ratio vitamin C and honey will be added in extract solution, be then 145 DEG C, air-out in EAT Temperature is dried in vacuo under conditions of being 72 DEG C, produces the feed addictive for promoting cold water fish growth, additive energy in water body A kind of unique taste is given out, induction cold water fish is ingested to feed, is increased food ration, is improved cold water fish growth rate, reach To the purpose for promoting growth;Additive contains a variety of biological effective components, can strengthen digestive enzyme activity, regulation gut flora knot Structure, suppress the breeding of pernicious bacteria, so as to effectively improve the growth performance of cold water fish;The amino in the muscle of cold water fish can be promoted Acid content changes, and can significantly improve protein content in muscle, fat content is reduced, wherein the amino with Titian function of odor Acid content has obvious rising, so as to reach the function of improving cold water meat quality of fish;Body can be strengthened should to the immune of extraneous pathogen Answer, strengthen the immunity and premunition of cold water fish, reduce the cultivation death rate.
A kind of purposes for the feed addictive for promoting cold water fish to grow:The feed addictive directly addition is entered in feed Row is fed, and addition is the 1.5% of feed relative, and the addition of feed addictive make it that the feed phagostimulating effect is good, the energy in water body A kind of unique taste is given out, induction cold water fish is ingested to feed, is increased food ration, is improved cold water fish growth rate, promotees Enter its growth;The utilization rate and high conversion rate of the feed, so as to effectively improve the growth performance of cold water fish, cold water can be significantly improved The function of meat quality of fish;Immune response of the body to extraneous pathogen can be strengthened, strengthen the immunity and premunition of cold water fish, reduced The death rate is cultivated, increases breeding income.
Embodiment 2:
A kind of feed addictive for promoting cold water fish growth, composition and its parts by weight are:18 parts of folium isatidis, 20 parts of cortex acanthopanacis, horse 12 parts of whip grass, 4 parts of dried orange peel, 8 parts of radix scutellariae, 7 parts of cape jasmine, 5 parts of mountain naphthalene, 5 parts of Radix Codonopsis, 1.2 parts of garlic, 0.4 part of vitamin C, honey 0.4 part.
A kind of preparation method for the feed addictive for promoting cold water fish to grow, specifically includes following steps:
1)Folium isatidis, cortex acanthopanacis, Verbena officinalis, dried orange peel, radix scutellariae, cape jasmine, mountain naphthalene, Radix Codonopsis, garlic are measured by formula, low temperature is continuously done Just crushed after dry, then ultramicro grinding to 500 mesh, produces medicinal powder, standby, and the continuous drying technique of low temperature can be reduced in Chinese herbal medicine The volatility of active ingredient, loss is reduced, the raw material of certain fineness can be provided for ultramicro grinding by just crushing, makes Ultramicro-powder It is broken to be more prone to carry out, the operating efficiency of ultramicro grinding is improved, reduces energy consumption, saves energy consumption and cost, ultramicro grinding energy Enough destroy Chinese herbal medicine cell membrane, intracellular effective drug ingedient is fully exposed, improve medicine bioavailability, The dosage of medicine is reduced, and improves the uniformity of particle to a certain extent, makes feed addictive easily dispersed In feed;
2)By in medicinal powder by weight:Volume=1:6 add vacuum drying 25h liquid chlorination 1- butyl -3- methylimidazole ionic liquids Body, adds active peptides, and the weight ratio of medicinal powder and active peptides is 1:0.002,6h is then stirred at 65 DEG C, mixed liquor is cold But to room temperature, water will then be added in mixed liquor, the weight ratio of medicinal powder and water is 1:12,10min is continuously stirred, filters, produces Extract solution, the amino acid sequence of above-mentioned active peptides is TDHKLCVCVNCFCCGAAKCYPFKYGVAGFYTHCGPNFCCCIS, The active peptides and ionic liquid collective effect are in the cell membrane of cell membrane, it is possible to increase the permeability of cell membrane is so as to improving medium-height grass It the recovery rate of active ingredient in medicine, can assist to improve the release of active ingredient and recovery rate in medicinal powder significantly, and extract effective Composition is easier to hydrolyze, and the extract solution is mainly polysaccharide, glucoside, alkaloid, organic acid, terpene and alcohols etc., has apparent Sterilizing effect, the resistance against diseases of cold water fish can be effectively improved, especially have improvement result to slow-growing fish, moreover it is possible to urge Fertilizer is got fat;Wherein medicinal ingredient energy enriching the blood and tonifying qi, good efficacy to suffering from a deficiency of the kidney, promotion is digested and assimilated and enhancing development;
3)Formula ratio vitamin C and honey will be added in extract solution, then dried, produce the feed addition for promoting cold water fish growth Agent, the additive can give out a kind of unique taste in water body, and induction cold water fish is ingested to feed, increases food ration, Cold water fish growth rate is improved, reaches the purpose for promoting growth;Additive contains a variety of biological effective components, can strengthen digestive ferment Activity, regulation intestinal microflora, suppress the breeding of pernicious bacteria, so as to effectively improve the growth performance of cold water fish;It can promote Amino acid content in the muscle of cold water fish changes, and can significantly improve protein content in muscle, reduces fat content, wherein Amino acid content with Titian function of odor has obvious rising, so as to reach the function of improving cold water meat quality of fish;Body can be strengthened To the immune response of extraneous pathogen, strengthen the immunity and premunition of cold water fish, reduce the cultivation death rate.
A kind of purposes for the feed addictive for promoting cold water fish to grow:The feed addictive directly addition is entered in feed Row is fed, and addition is the 1.2% of feed relative, and the addition of feed addictive make it that the feed phagostimulating effect is good, the energy in water body A kind of unique taste is given out, induction cold water fish is ingested to feed, is increased food ration, is improved cold water fish growth rate, promotees Enter its growth;The utilization rate and high conversion rate of the feed, so as to effectively improve the growth performance of cold water fish, cold water can be significantly improved The function of meat quality of fish;Immune response of the body to extraneous pathogen can be strengthened, strengthen the immunity and premunition of cold water fish, reduced The death rate is cultivated, increases breeding income.
Embodiment 3:
A kind of feed addictive for promoting cold water fish growth, composition and its parts by weight are:Folium isatidis 21g, cortex acanthopanacis 17g, horsewhip Careless 13g, dried orange peel 3g, radix scutellariae 9g, cape jasmine 5g, mountain naphthalene 7g, Radix Codonopsis 3g, garlic 2g, vitamin C 0.3g, honey 0.5g.
It is a kind of promote cold water fish growth the preparation method of feed addictive be:Folium isatidis, cortex acanthopanacis, horse are measured by formula Whip grass, dried orange peel, radix scutellariae, cape jasmine, mountain naphthalene, Radix Codonopsis, garlic, just crushed after low temperature is continuous drying, then ultramicro grinding to 700 mesh, By in gained medicinal powder by weight:Volume=1:8 add vacuum drying 24h liquid chlorination 1- butyl -3- methylimidazole ionic liquids Body, adds active peptides, and the weight ratio of medicinal powder and active peptides is 1:0.004,4h is then stirred at 72 DEG C, mixed liquor is cold But to room temperature, water will then be added in mixed liquor, the weight ratio of medicinal powder and water is 1:15,6min is continuously stirred, filters, will filter Formula ratio vitamin C and honey are added in liquid, is then dried, produces the feed addictive for promoting cold water fish growth.
A kind of purposes for the feed addictive for promoting cold water fish to grow:The feed addictive directly addition is entered in feed Row is fed, and addition is the 1.7% of feed relative.
Routine operation in the operating procedure of the present invention is well known to those skilled in the art, herein without repeating.
Technical scheme is described in detail embodiment described above, it should be understood that it is described above only For the specific embodiment of the present invention, it is not intended to limit the invention, all any modifications made in the spirit of the present invention, Supplement or similar fashion replacement etc., should be included in the scope of the protection.
SEQUENCE LISTING
<110>Tonghua Teachers College
<120>A kind of feed addictive for promoting cold water fish growth and application thereof
<130> 1
<160> 1
<170> PatentIn version 3.5
<210> 1
<211> 42
<212> PRT
<213>It is artificial synthesized
<400> 1
Thr Asp His Lys Leu Cys Val Cys Val Asn Cys Phe Cys Cys Gly Ala
1 5 10 15
Ala Lys Cys Tyr Pro Phe Lys Tyr Gly Val Ala Gly Phe Tyr Thr His
20 25 30
Cys Gly Pro Asn Phe Cys Cys Cys Ile Ser
35 40

Claims (9)

  1. A kind of 1. feed addictive for promoting cold water fish growth, it is characterised in that:The composition and its parts by weight of described additive For:Folium isatidis 17-22 parts, cortex acanthopanacis 16-22 parts, Verbena officinalis 11-15 parts, dried orange peel 2-4 parts, radix scutellariae 7-10 parts, cape jasmine 5-7 parts, Mountain naphthalene 5-8 parts, Radix Codonopsis 3-5 parts, garlic 1-2 parts, vitamin C 0.2-0.5 parts, honey 0.3-0.6 parts.
  2. A kind of 2. feed addictive for promoting cold water fish growth according to claim 1, it is characterised in that:Described addition The preparation process of agent includes:It is prepared by pretreatment of raw material, ionic liquid assisted extraction, additive.
  3. A kind of 3. preparation method of feed addictive for promoting cold water fish to grow according to claim 2, it is characterised in that: Described ionic liquid assisted extraction step is:Liquid chlorination 1- butyl -3- methylimidazole ionic liquids will be added in medicinal powder, then Active peptides, stirring are added, mixed liquor is cooled to room temperature, then water will be added in mixed liquor, continuously stirred, and filters, produces and carry Take liquid.
  4. A kind of 4. preparation method of feed addictive for promoting cold water fish to grow according to claim 3, it is characterised in that: Described ionic liquid assisted extraction step traditional Chinese medicine powder and the weight ratio of active peptides are 1:0.002-0.004, active peptides Amino acid sequence is TDHKLCVCVNCFCCGAAKCYPFKYGVAGFYTHCGPNFCCCIS.
  5. A kind of 5. preparation method of feed addictive for promoting cold water fish to grow according to claim 3, it is characterised in that: Described ionic liquid assisted extraction step traditional Chinese medicine powder and the weight of liquid chlorination 1- butyl -3- methylimidazole ionic liquids:Body Product=1:6-8.
  6. A kind of 6. preparation method of feed addictive for promoting cold water fish to grow according to claim 3, it is characterised in that: The vacuum dried 22- of liquid chlorination 1- butyl -3- methylimidazole ionic liquids in described ionic liquid assisted extraction step 26h。
  7. A kind of 7. preparation method of feed addictive for promoting cold water fish to grow according to claim 3, it is characterised in that: After adding ionic liquid in described ionic liquid assisted extraction step 4-6h is stirred at 65-75 DEG C.
  8. A kind of 8. preparation method of feed addictive for promoting cold water fish to grow according to claim 3, it is characterised in that: Described ionic liquid assisted extraction step traditional Chinese medicine powder and the weight ratio of water are 1:12-15,5-10min is continuously stirred after adding water.
  9. A kind of 9. purposes for the feed addictive for promoting cold water fish to grow, it is characterised in that:Described purposes is:The feed is added Add agent directly to add to be fed in feed, addition is the 1-2% of feed relative.
CN201710596275.XA 2017-07-20 2017-07-20 A kind of feed addictive for promoting cold water fish growth and application thereof Pending CN107361243A (en)

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Application Number Priority Date Filing Date Title
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Cited By (3)

* Cited by examiner, † Cited by third party
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CN108157678A (en) * 2017-12-29 2018-06-15 磐安县派普特生物科技有限公司 A kind of preparation method containing Auricularia polysaccharide preparing grass carp feed additive
CN111436554A (en) * 2020-04-14 2020-07-24 安徽斯普瑞生物科技有限公司 Preparation method of edible and medicinal fungus solid beverage
CN111567676A (en) * 2020-05-15 2020-08-25 山东省海洋资源与环境研究院 Special nutrition enhancer for parent fish of cold water fish and use method thereof

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CN108157678A (en) * 2017-12-29 2018-06-15 磐安县派普特生物科技有限公司 A kind of preparation method containing Auricularia polysaccharide preparing grass carp feed additive
CN111436554A (en) * 2020-04-14 2020-07-24 安徽斯普瑞生物科技有限公司 Preparation method of edible and medicinal fungus solid beverage
CN111567676A (en) * 2020-05-15 2020-08-25 山东省海洋资源与环境研究院 Special nutrition enhancer for parent fish of cold water fish and use method thereof

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