CN107296784A - A kind of skin whitening, moisturizing fermentation Chinese wolfberry fruit liquid level film and preparation method thereof - Google Patents
A kind of skin whitening, moisturizing fermentation Chinese wolfberry fruit liquid level film and preparation method thereof Download PDFInfo
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- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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Abstract
The invention belongs to cosmetic skin field, and in particular to a kind of skin whitening, moisturizing fermentation Chinese wolfberry fruit liquid level film and preparation method thereof.The matrimony vine facial mask of the present invention includes the facial mask stoste of spunlace non-woven cloth Face film towel and infiltration on spunlace non-woven cloth；Facial mask stoste includes following components：Pure water, fermentation Chinese wolfberry fruit liquid, polyglutamic acid, vitamin C, asparagus juice, pearl powder, propane diols, chitosan oligomer, ganoderma lucidum fermented liquid, Radix Sangusorbae extract and angelica extract and pulullan polysaccharide.The reparation facial mask of the present invention is when laying, chitosan oligomer and angelica extract, which can take the lead in entering in Skin Cell, carries out bactericidal antiphlogistic, then polyglutamic acid can control the slow reparation and cytothesis for being extracted into skin, carrying out cell of ganoderma lucidum fermented liquid, garden burnet and the nutritional ingredient in fermentation Chinese wolfberry fruit liquid.The sun-proof reparation facial mask of the present invention effectively controls each nutritional ingredient into the order of Skin Cell, by mutually being cooperateed between each component, collective effect, quick repair cell.
Description
Technical field
The invention belongs to cosmetic skin field, and in particular to a kind of skin whitening, moisturizing fermentation Chinese wolfberry fruit liquid level film and its preparation side
Method.
Background technology
Skin is made up of epidermis, basilar memebrane and skin corium from outside to inside.Epidermis is divided into cuticula, stratum granulosum, had again
Spinous layer and basalis.It is 5~20 layers of dead pinacocyte positioned at the cuticula of body surface, when cuticula is blocked up or water content is low
When, the ability of skin reflex light reduces and the dull colour of skin is presented；In addition, originating from the melanin in basal layer of epidermis to light
The absorbability of line is most strong, and the colour of skin that melanin content is more at most presented is deeper；Further, in corium angioplerosis degree not enough or
Poor blood circulation, then hemochrome cohesion or content, which decline, causes the colour of skin dark red or pale；Finally, the collagenous fibres in corium
Skin tension and toughness are assigned, its skewness or structure change will cause light uniformly to be reflected and cause the colour of skin
It is uneven and lackluster.
Although present social pressures are increased, the pressure stayed up late of working overtime is rested bad, sleep is not into the daily of modern
Foot, is the most active moment of skin cell renewal during the length of one's sleep in evening, sleeps or have not enough sleep too late, metabolic function
No longer smoothly, cause aging cutin layer to thicken, skin loses transparent feel, the dark color of graying is presented.When we bear pressure, fatigue
When excessive, body can be in tension, causes vessel retraction, poor circulation, and face is also obscure to get off.And tired mistake
Degree, the sluggish metabolism of skin, face becomes more obscure because cutin is gathered.If scaly dry skin, cuticula moisture is not
Foot, the colour of skin seems dark yellow.And microgroove occurs in the skin dried, do not see to be difficult to observe carefully sometimes, but more than microgroove
Skin is just as having covered one layer of ash, it appears dark yellow.Some and skin senescence have after certain relation, skin senescence above, new old generation
Thank and slow down, skin is oxidized.The colour of skin is intense darkness without light coloured silk.
Whitening is the dream of each woman, is at this moment just badly in need of a skin whitening, moisturizing fermentation Chinese wolfberry fruit liquid level film to repair skin,
And the complex manufacturing technology of the most cosmetics of in the market and contain artificial synthesized chemicals mostly, easily stimulate and arrive skin, especially
It is some skin sensitivities crowd and the crowd of particular time, causes allergy, people is produced query to the composition of cosmetics.
Matrimony vine, the also known as fruit of Chinese wolfberry, are Solanaceae deciduous plant (Lycium chintnse) or lycium barbarum (Lycium
Barbarum ripening fruits), is famous nourishing Chinese medicine, is included in by health ministry《It is both food and the article of medicine
List》.Modern pharmacological research result shows that matrimony vine is except having reducing blood lipid known to people, decompression, hypoglycemic, enhancing body to exempt from
Epidemic disease function etc. is acted on, moreover it is possible to make erythrocyte sod activity rise.Its polysaccharide Wheat Protein, to safeguarding the normal of human body cell
Develop, improve DNA repair ability and promote senile cell to be reversed to young direction and all play beneficial effect.The chemistry of matrimony vine
Composition mainly contains LBP-X (LBP), glycine betaine, carotenoid and carotenoid ester, vitamin C, several amino acids and
Various trace elements.Because of place of production difference, component content slightly has difference to matrimony vine.By the fermentation process of saccharomycete, Chinese holly can be lifted
The absorbability of the nutriment of Qi, converts some compositions to skin sensitivity, reduces allergic reaction.
The application for preparing facial mask using matrimony vine is existing a lot, such as refer in patent CN201610219829.X a kind of black
Matrimony vine facial mask, it uses lycium ruthenicum to take its extract solution after grinding, then constitutes the raw materials such as itself and cucumber, its process be not related to by
Fermentation Chinese wolfberry fruit prepares facial mask technique.A kind of preparation method of matrimony vine facial mask is relate in patent CN201610830191.3, by Chinese holly
Qi zymotic fluid, collagen, vitamin C, asparagus juice pearl powder and propane diols simply compounding are formed.The advantage of the above method is to adopt
With pure natural raw material as facial mask stoste, fermentation Chinese wolfberry fruit liquid is added, is not destroyed based on active ingredient at utmost, retain matrimony vine hair
Active ingredient in zymotic fluid, obtained facial mask has moisturizing, whitening, effect of anti-aging, but it makes to different crowd
It is need to be improved with effect.
Therefore, the using effect of matrimony vine facial mask how is further improved, it is to need at present preferably to play skin whitening, moisturizing effect
The technical problem to be solved.
The content of the invention
The purpose of the present invention is that there is provided a kind of skin whitening, moisturizing fermentation Chinese wolfberry fruit liquid level film and its system in view of the shortcomings of the prior art
Preparation Method.It is compound in ganoderma lucidum fermented liquid and fermentation Chinese wolfberry fruit liquid mixed liquor in the skin whitening, moisturizing fermentation Chinese wolfberry fruit liquid level film of the present invention
Polysaccharide, with synergy, can effectively remove free radical and suppress the activity of tyrosinase, deep layer repair cell gives skin
With nutrition, impaired cell, tissue can be made to obtain timely high-quality repairing, make skin gloss high resilience, delaying senility.Ground
The active component that elm contains can effectively suppress the activity of tyrosinase, the synthesis of DOPA and DOPA quinone be blocked, so as to contain black
The growth of element, therefore with skin brightening effect.The angelica extract promoting flow of qi and blood circulation, increases velocity of blood flow, blood circulation is skin
Fibroblast, collagen etc. sufficient oxygen and nutriment are provided；Be conducive to the metabolite of cell and various
Harmful substance is removed in time, it is ensured that the metabolism of skin.This composition of the polyglutamic acid that the present invention is used, because its is larger
Strand and large number of ultrahydrophilic group (- COOH), can make ganoderma lucidum fermented liquid, Radix Sangusorbae extract, matrimony vine hair
Effectively absorption is around its strand in zymotic fluid, chitosan oligomer and Radix Angelicae Sinensis.In addition, substantial amounts of-NH in oligopolymerization chitosan glycan molecule3
Make it have positive charge, enable chitosan oligomer effectively with the collagen in skin etc. is quick combines, pro-skin performance is very
It is good；Therefore, when laying facial mask, chitosan oligomer, which can take the lead in entering in Skin Cell, carries out bactericidal antiphlogistic, then polyglutamic acid
Ganoderma lucidum fermented liquid, garden burnet and the nutritional ingredient in fermentation Chinese wolfberry fruit liquid can be controlled is slowly extracted into skin successively again, carries out thin
The reparation and cytothesis of born of the same parents.The sun-proof reparation facial mask of the present invention effectively controls each nutritional ingredient into the order of Skin Cell,
By mutually being cooperateed between each component, collective effect, quick repair cell.
To achieve the above object, the present invention is adopted the following technical scheme that：
A kind of skin whitening, moisturizing fermentation Chinese wolfberry fruit liquid level film, the skin whitening, moisturizing fermentation Chinese wolfberry fruit liquid level film includes spunlace non-woven cloth face
The facial mask stoste of film towel and infiltration on spunlace non-woven cloth；The facial mask stoste includes the component of following parts by weight：
The molecular weight of the polyglutamic acid is 91-101 ten thousand.
It is used as preferred technical scheme：
It is preferred that, the molecular weight of the chitosan oligomer is 1300-1600；Fermentation Chinese wolfberry fruit liquid is lycium ruthenicum zymotic fluid.
It is preferred that, the lactic acid bacteria used during fermentation Chinese wolfberry fruit liquid and the ganoderma lucidum fermented liquid fermentation is CGMCC NO.1.1 breasts
Sour bacterium.
After lactic fermentation, pH declines, and oxidation-reduction potential rises, and environment is in reduction-state.Therefore, lactobacillus-fermented ganoderma lucidum is used
And matrimony vine, the polysaccharide in ganoderma lucidum and matrimony vine can be made fully to preserve, enable nutritional ingredient in matrimony vine and ganoderma lucidum more fully
Using and release.
It is preferred that, the particle diameter of the pearl powder is 100-200nm；The molecular weight of the pulullan polysaccharide is 20-40 ten thousand.
It is preferred that, the facial mask stoste includes the component of following parts by weight：30 parts of pure water, 28 parts of fermentation Chinese wolfberry fruit liquid,
3 parts of polyglutamic acid, 0.4 part of vitamin C, 16 parts of asparagus juice, 12 parts of pearl powder, 0.5 part of propane diols, 3 parts of chitosan oligomer, spirit
5 parts of 8 parts of sesame zymotic fluid, 5 parts of Radix Sangusorbae extract, 2 parts of angelica extract and pulullan polysaccharide；The molecular weight of the polyglutamic acid is
950000.
Present invention also offers a kind of preparation method of skin whitening, moisturizing fermentation Chinese wolfberry fruit liquid level film, it is characterized in that, including it is following
Step：
(1) polyglutamic acid and pearl powder are dissolved in pure water, and stirred, become thick liquid；
(2) asparagus juice is added in aforesaid liquid, sequentially adds vitamin C, propane diols, pulullan polysaccharide and matrimony vine
Zymotic fluid, chitosan oligomer, ganoderma lucidum fermented liquid, Radix Sangusorbae extract and angelica extract are stirred and evenly mixed, and obtain facial mask stoste；
(3) after facial mask stoste is sterilized, then spunlace non-woven cloth Face film towel soaked in facial mask stoste, then vacuum seal
Dress, is made matrimony vine facial mask.
It is preferred that, by dry wolfberry and water in mass ratio 1:The abundant mashing of 8-15 mixing, based on liquid, into basal liquid plus
Enter following percentage by weight material：Yeast extract 0.1-0.4%, dipotassium hydrogen phosphate 0.03-0.2%, magnesium sulfate 0.01-
0.2%, Triammonium citrate 0.1-0.2%, manganese sulfate 0.001-0.005%, sterilize, inoculating lactic acid bacterium is placed in after fully mixing
180rpm on shaking table, cultivates 48h, obtains fermentation Chinese wolfberry fruit stoste by 30 DEG C；By the fermenation raw liquid filtration sterilization, retain supernatant simultaneously
The pH value of supernatant is adjusted to neutrality, fermentation Chinese wolfberry fruit liquid is obtained.
It is preferred that, the stir speed (S.S.) used when being stirred in step (1) or step (2) is 80-100r/min；In step (3)
The time of immersion is 30-40min.
It is preferred that, ganoderma lucidum fermented liquid is identical with the preparation method of fermentation Chinese wolfberry fruit liquid.
It is preferred that, the extracting method of angelica extract and Radix Sangusorbae extract is：After the extract that will be prepared is crushed, add
Volume fraction filters for 30%-95% ethanol solution；Then it is placed in after filtered fluid is concentrated on large pore resin absorption column, with same
After the ethanol solution elution of sample volume fraction, dry and obtain the extract.
Inventive principle：
Chitosan oligomer and angelica extract in the present invention have good inhibiting bacteria and diminishing inflammation and moisturizing effects.Oligopolymerization chitosan
Substantial amounts of-NH in glycan molecule3Presence it is carried positive charge, can effectively with the collagen in skin etc. is quick combines,
Pro-skin performance is very good；Therefore, when laying facial mask, chitosan oligomer, which can take the lead in entering in Skin Cell, carries out moisturizing, makes thin
Born of the same parents fill, and then polyglutamic acid can control the slow molten of ganoderma lucidum fermented liquid, garden burnet, Radix Angelicae Sinensis and the nutritional ingredient in fermentation Chinese wolfberry fruit liquid
Go out and enter skin, carry out the reparation and cytothesis of cell.
Due to, containing the ultrahydrophilic group (- COOH) of more than 1000, can fully keep water in polyglutamic acid molecule
Point, for improving voidage in matrimony vine facial mask between nutritional ingredient, beneficial to ganoderma lucidum fermented liquid, garden burnet, Radix Angelicae Sinensis and fermentation Chinese wolfberry fruit
The effectively nutritional ingredient such as liquid absorbs, and can be absorbed in skin surface formation thin film protection skin, be nutrient, water in sun-proof facial mask
Optimal transport platform point with Touch skin familiarity, effectively increase the dissolving in sun-proof facial mask active ingredient, storage, convey and
Absorb.In addition, polyglutamic acid has hydrophilic radical, carboxyl is ionizable negatively charged, the adsorbable nutritional ingredient of negative electrical charge；Applying
If during facial mask, absorption is in polyglutamic acid group surrounding nutrient composition, the intermolecular force for being acted on and being seen with skin due to concentration difference
Under, polyglutamic acid can slowly release above-mentioned nutritional ingredient, during face mask film, can make moisture and the uniform dissolution of nutrition,
So that skin slow-absorbing.Also need to propose, due to the nutrition in ganoderma lucidum fermented liquid, garden burnet, Radix Angelicae Sinensis, fermentation Chinese wolfberry fruit liquid into
Dividing includes the materials such as Flavonoid substances, beta carotene, forulic acid, Ligustilide, polysaccharose substance, due to them and polyglutamic
The active force of acid is different, during sustained release, is usually that Flavonoid substances, forulic acid and polysaccharose substance are carried out into cell
Repair and cytothesis, be finally that the materials such as beta carotene and Ligustilide enter cell enhancing cell viability, shine skin.
The sun-proof reparation facial mask of the present invention effectively controls each nutritional ingredient into the order of Skin Cell, by mutually being assisted between each component
Together, collective effect, quick repair cell.
Therefore, using pure natural polyglutamic acid, this is not merely that instead of collagen, hyaluronic acid, glycerine to the present invention
Etc. this moisturizing ingredient, moreover it is possible to fermentation Chinese wolfberry fruit liquid, ganoderma lucidum fermented liquid and garden burnet and chitosan oligomer and angelica extract etc.
Synergy, makes the using effect of matrimony vine facial mask more preferable.
Beneficial effect：
Polyglutamic acid has extremely strong moisture retention, can form layer protecting film on skin to prevent the steaming of skin moisture
Hair, it can penetrate into skin deep layer, self moisture-keeping system of recovery skin.With advancing age with the aggravation of physical fatigue,
The function of profit certainly of skin can gradually weaken, or even disappear, and the facial mask that with the addition of polyglutamic acid can repair the profit work(certainly of skin
Energy.Therefore polyglutamic acid has good beauty protecting effect for the skin of the mankind.
Polyglutamic acid be it is a kind of water-soluble, it is biodegradable, be a kind of to the high-end of the nutritious effect of skin without toxicity
Product, is completely suitable for all skins, and provide the lasting moistening effect better than hyaluronic acid and collagen, it is only necessary to
Very low concentration, it is possible to reach good effect, therefore cost is very low.Available for skin care item, shampoo, hair-cream, shaving cream
In lipstick.Therefore, matrimony vine preparation method of the invention is easy, and feasibility is high, it is easy to promote production, and cost is not high.
The present invention polyglutamic acid this be not merely instead of this moisturizing of collagen, hyaluronic acid, glycerine etc. into
Point, polyglutamic acid of the invention not only has extremely strong moisture retention, moreover it is possible to fermentation Chinese wolfberry fruit liquid, ganoderma lucidum fermented liquid and garden burnet, association
Same-action, makes the using effect of sun-proof facial mask more preferable.
The present invention uses the fermentation Chinese wolfberry fruit liquid of lactobacillus-fermented, and some skins of farthest degrading are not easy to absorb and easy
The material of sensitization, retains the active ingredient in fermentation Chinese wolfberry fruit liquid, and the facial mask of preparation has moisturizing, a whitening, effect of anti-aging,
There is certain effect to different crowd.
The ganoderma lucidum hair polysaccharide and LBP-X that the present invention is used mutually are cooperateed with, and can effectively be removed free radical and be suppressed tyrosine
The activity of enzyme, deep layer repair cell gives skin with nutrition, and impaired cell, tissue can be made to obtain timely high-quality repairing,
Make skin gloss high resilience, delaying senility.
In the skin whitening, moisturizing fermentation Chinese wolfberry fruit liquid level film of the present invention, the active component that garden burnet contains can effectively suppress tyrosinase
Activity, the synthesis of DOPA and DOPA quinone is blocked, so as to contain the growth of melanin, therefore with skin brightening effect.
In the skin whitening, moisturizing fermentation Chinese wolfberry fruit liquid level film of the present invention, the angelica extract promoting flow of qi and blood circulation increases velocity of blood flow, blood
Circulate oxygen and nutriment that fibroblast, collagen for skin etc. provide abundance；Be conducive to the metabolism of cell
Product and various harmful substances are removed in time, it is ensured that the metabolism of skin.
The present invention is using substantial amounts of-NH in oligopolymerization chitosan glycan molecule3With the presence of the highly polar groups of-OH, make itself not
Only make chitosan oligomer that there is good moisture-absorbing moisture-keeping function, transepidermal water can be hydrated again, protected so as to play humidification
Wet effect.Moreover, the good gas permeability of chitosan oligomer does not disturb excretion of the epidermis to waste and toxin again, skin is not resulted in
Acne.The skin-protection product of chitosan oligomer also plays the role of easily to be absorbed by the skin, stimulated circulation.
Black fruit fructus lycii whitening and moisturizing smoothing toner and preparation method of smoothing toner provided by the present invention, active matter is used as using the extract of pure natural product
Matter, without ethanol, is not stimulated without any toxicity and side effects, gently, its active ingredient is excellent to be absorbed by the skin by aquation, is prevented
Only the moisture evaporation in cuticula is reduced, with good replenishing water and preserving moisture, skin care, supplement skin-nourishing, cutin-softening, whitening
Nti-freckle, prevent skin aging, isolating and protecting, improve skin quality, keep skin vigor effect；Both it can overcome the disadvantages that generalization adornment water could not
The weak point of effective wetting, can overcome again common skin care item can not moisturizing whitening rapidly shortcoming, it is adaptable to various skin quality
Consumer.
Embodiment
The invention will be further elucidated with reference to specific embodiments.It should be understood that these embodiments are merely to illustrate this hair
Bright rather than limitation the scope of the present invention.In addition, it is to be understood that after the content of the invention lectured has been read, art technology
Personnel can make various changes or modifications to the present invention, and these equivalent form of values equally fall within the application appended claims and limited
Fixed scope.
Embodiment 1
The present invention skin whitening, moisturizing fermentation Chinese wolfberry fruit liquid level film, by weight, including composition it is as follows：
25 parts of pure water；
20 parts of fermentation Chinese wolfberry fruit liquid；
2 parts of polyglutamic acid；Molecular weight is 950,000
0.3 part of vitamin C；
15 parts of asparagus juice；
10 parts of pearl powder；The particle diameter of pearl powder is 100 nanometers；
0.3 part of propane diols；
2 parts of chitosan oligomer；Molecular weight is 1300；
10 parts of ganoderma lucidum fermented liquid；
6 parts of Radix Sangusorbae extract；
1 part of angelica extract；
2 parts of pulullan polysaccharide；Molecular weight is 200,000；
The preparation method of the skin whitening, moisturizing fermentation Chinese wolfberry fruit liquid level film of the present invention, comprises the following steps：In prepared by matrimony vine facial mask
The addition of each component is identical with the parts by weight of each component in above-mentioned matrimony vine facial mask；
(1) polyglutamic acid and pearl powder are dissolved in pure water, and stirred, stir speed (S.S.) is 80r/min, make its into
For thick liquid；
(2) asparagus juice is added in aforesaid liquid, sequentially adds vitamin C, propane diols, pulullan polysaccharide and matrimony vine
Zymotic fluid, chitosan oligomer, ganoderma lucidum fermented liquid, Radix Sangusorbae extract and angelica extract are stirred and evenly mixed, and stir speed (S.S.) is 80r/
Min, obtains facial mask stoste；Ganoderma lucidum fermented liquid is identical with the preparation method of fermentation Chinese wolfberry fruit liquid.
(3) after facial mask stoste is sterilized, then spunlace non-woven cloth Face film towel soaked into 30min, Ran Houzhen in facial mask stoste
Sky encapsulation, is made matrimony vine facial mask.
Wherein fermentation Chinese wolfberry fruit liquid and preparation method thereof is as follows：By dry wolfberry and water in mass ratio 1:8 mixing fully mashing, is used as base
Plinth liquid, following percentage by weight material is added into basal liquid：Yeast extract 0.1%, dipotassium hydrogen phosphate 0.03%, magnesium sulfate
0.01%, Triammonium citrate 0.1%, manganese sulfate 0.001% sterilizes, inoculating lactic acid bacterium is placed on shaking table after fully mixing
180rpm, cultivates 48h, obtains fermentation Chinese wolfberry fruit stoste by 30 DEG C；By the fermenation raw liquid filtration sterilization, retain supernatant and by supernatant
The pH value of liquid is adjusted to neutrality, obtains fermentation Chinese wolfberry fruit liquid.Lactic acid bacteria is CGMCC NO.1.1 lactic acid bacterias.
The extracting method of angelica extract and Radix Sangusorbae extract is：After the extract that will be prepared is crushed, volume integral is added
Number filters for 45% ethanol solution；Then it is placed in after filtered fluid is concentrated on large pore resin absorption column, uses same volume fraction
Ethanol solution elution after, dry and obtain the extract.
Embodiment 2
The present invention skin whitening, moisturizing fermentation Chinese wolfberry fruit liquid level film, by weight, including composition it is as follows：
40 parts of pure water；
22 parts of fermentation Chinese wolfberry fruit liquid；
4 parts of polyglutamic acid；Molecular weight is 910,000
0.4 part of vitamin C；
16 parts of asparagus juice；
12 parts of pearl powder；The particle diameter of pearl powder is 200 nanometers；
0.4 part of propane diols；
5 parts of chitosan oligomer；Molecular weight is 1600；
5 parts of ganoderma lucidum fermented liquid；
3 parts of Radix Sangusorbae extract；
3 parts of angelica extract；
4 parts of pulullan polysaccharide；Molecular weight is 250,000；
The preparation method of the skin whitening, moisturizing fermentation Chinese wolfberry fruit liquid level film of the present invention, comprises the following steps：In prepared by matrimony vine facial mask
The addition of each component is identical with the parts by weight of each component in above-mentioned matrimony vine facial mask；
(1) polyglutamic acid and pearl powder are dissolved in pure water, and stirred, stir speed (S.S.) is 90r/min, make its into
For thick liquid；
(2) asparagus juice is added in aforesaid liquid, sequentially adds vitamin C, propane diols, pulullan polysaccharide and matrimony vine
Zymotic fluid, chitosan oligomer, ganoderma lucidum fermented liquid, Radix Sangusorbae extract and angelica extract are stirred and evenly mixed, and stir speed (S.S.) is 90r/
Min, obtains facial mask stoste；Ganoderma lucidum fermented liquid is identical with the preparation method of fermentation Chinese wolfberry fruit liquid.
(3) after facial mask stoste is sterilized, then spunlace non-woven cloth Face film towel soaked into 35min, Ran Houzhen in facial mask stoste
Sky encapsulation, is made matrimony vine facial mask.
Wherein fermentation Chinese wolfberry fruit liquid and preparation method thereof is as follows：By dry wolfberry and water in mass ratio 1:8 mixing fully mashing, is used as base
Plinth liquid, following percentage by weight material is added into basal liquid：Yeast extract 0.1%, dipotassium hydrogen phosphate 0.03%, magnesium sulfate
0.01%, Triammonium citrate 0.1%, manganese sulfate 0.001% sterilizes, inoculating lactic acid bacterium is placed on shaking table after fully mixing
180rpm, cultivates 48h, obtains fermentation Chinese wolfberry fruit stoste by 30 DEG C；By the fermenation raw liquid filtration sterilization, retain supernatant and by supernatant
The pH value of liquid is adjusted to neutrality, obtains fermentation Chinese wolfberry fruit liquid.Lactic acid bacteria is CGMCC NO.1.1 lactic acid bacterias.
The extracting method of angelica extract and Radix Sangusorbae extract is：After the extract that will be prepared is crushed, volume integral is added
Number filters for 75% ethanol solution；Then it is placed in after filtered fluid is concentrated on large pore resin absorption column, uses same volume fraction
Ethanol solution elution after, dry and obtain the extract.
Embodiment 3
The present invention skin whitening, moisturizing fermentation Chinese wolfberry fruit liquid level film, by weight, including composition it is as follows：It is prepared by matrimony vine facial mask
The addition of middle each component is identical with the parts by weight of each component in above-mentioned matrimony vine facial mask；
30 parts of pure water；
25 parts of fermentation Chinese wolfberry fruit liquid；
3 parts of polyglutamic acid；Molecular weight is 1,000,000
0.4 part of vitamin C；
17 parts of asparagus juice；
15 parts of pearl powder；The particle diameter of pearl powder is 100 nanometers；
0.8 part of propane diols；
4 parts of chitosan oligomer；Molecular weight is 1400；
6 parts of ganoderma lucidum fermented liquid；
4 parts of Radix Sangusorbae extract；
2 parts of angelica extract；
5 parts of pulullan polysaccharide；Molecular weight is 300,000；
The preparation method of the skin whitening, moisturizing fermentation Chinese wolfberry fruit liquid level film of the present invention, comprises the following steps：In prepared by matrimony vine facial mask
The addition of each component is identical with the parts by weight of each component in above-mentioned matrimony vine facial mask；
(1) polyglutamic acid and pearl powder are dissolved in pure water, and stirred, stir speed (S.S.) is 100r/min, makes it
As thick liquid；
(2) asparagus juice is added in aforesaid liquid, sequentially adds vitamin C, propane diols, pulullan polysaccharide and matrimony vine
Zymotic fluid, chitosan oligomer, ganoderma lucidum fermented liquid, Radix Sangusorbae extract and angelica extract are stirred and evenly mixed, and stir speed (S.S.) is 100r/
Min, obtains facial mask stoste；Ganoderma lucidum fermented liquid is identical with the preparation method of fermentation Chinese wolfberry fruit liquid.
(3) after facial mask stoste is sterilized, then spunlace non-woven cloth Face film towel soaked into 40min, Ran Houzhen in facial mask stoste
Sky encapsulation, is made matrimony vine facial mask.
Wherein fermentation Chinese wolfberry fruit liquid and preparation method thereof is as follows：By dry wolfberry and water in mass ratio 1:15 mixing fully mashing, as
Basal liquid, following percentage by weight material is added into basal liquid：Yeast extract 0.4%, dipotassium hydrogen phosphate 0.2%, sulfuric acid
Magnesium 0.2%, Triammonium citrate 0.2%, manganese sulfate 0.005% sterilizes, inoculating lactic acid bacterium is placed on shaking table after fully mixing
180rpm, cultivates 48h, obtains fermentation Chinese wolfberry fruit stoste by 30 DEG C；By the fermenation raw liquid filtration sterilization, retain supernatant and by supernatant
The pH value of liquid is adjusted to neutrality, obtains fermentation Chinese wolfberry fruit liquid.Lactic acid bacteria is CGMCC NO.1.1 lactic acid bacterias.
The extracting method of angelica extract and Radix Sangusorbae extract is：After the extract that will be prepared is crushed, volume integral is added
Number filters for 60% ethanol solution；Then it is placed in after filtered fluid is concentrated on large pore resin absorption column, uses same volume fraction
Ethanol solution elution after, dry and obtain the extract.
Embodiment 4
The present invention skin whitening, moisturizing fermentation Chinese wolfberry fruit liquid level film, by weight, including composition it is as follows：
40 parts of pure water；
35 parts of fermentation Chinese wolfberry fruit liquid；
3 parts of polyglutamic acid；Molecular weight is 1,000,000
0.5 part of vitamin C；
20 parts of asparagus juice；
15 parts of pearl powder；The particle diameter of pearl powder is 100 nanometers；
0.8 part of propane diols；
3 parts of chitosan oligomer；Molecular weight is 1500；
7 parts of ganoderma lucidum fermented liquid；
5 parts of Radix Sangusorbae extract；
2.5 parts of angelica extract；
3 parts of pulullan polysaccharide；Molecular weight is 200,000；
The preparation method of the skin whitening, moisturizing fermentation Chinese wolfberry fruit liquid level film of the present invention, comprises the following steps：In prepared by matrimony vine facial mask
The addition of each component is identical with the parts by weight of each component in above-mentioned matrimony vine facial mask；
(1) polyglutamic acid and pearl powder are dissolved in pure water, and stirred, stir speed (S.S.) is 85r/min, make its into
For thick liquid；
(2) asparagus juice is added in aforesaid liquid, sequentially adds vitamin C, propane diols, pulullan polysaccharide and matrimony vine
Zymotic fluid, chitosan oligomer, ganoderma lucidum fermented liquid, Radix Sangusorbae extract and angelica extract are stirred and evenly mixed, and stir speed (S.S.) is 85r/
Min, obtains facial mask stoste；Ganoderma lucidum fermented liquid is identical with the preparation method of fermentation Chinese wolfberry fruit liquid.
(3) after facial mask stoste is sterilized, then spunlace non-woven cloth Face film towel soaked into 33min, Ran Houzhen in facial mask stoste
Sky encapsulation, is made matrimony vine facial mask.
Wherein fermentation Chinese wolfberry fruit liquid and preparation method thereof is as follows：By dry wolfberry and water in mass ratio 1:15 mixing fully mashing, as
Basal liquid, following percentage by weight material is added into basal liquid：Yeast extract 0.4%, dipotassium hydrogen phosphate 0.2%, sulfuric acid
Magnesium 0.2%, Triammonium citrate 0.2%, manganese sulfate 0.005% sterilizes, inoculating lactic acid bacterium is placed on shaking table after fully mixing
180rpm, cultivates 48h, obtains fermentation Chinese wolfberry fruit stoste by 30 DEG C；By the fermenation raw liquid filtration sterilization, retain supernatant and by supernatant
The pH value of liquid is adjusted to neutrality, obtains fermentation Chinese wolfberry fruit liquid.Lactic acid bacteria is CGMCC NO.1.1 lactic acid bacterias.
The extracting method of angelica extract and Radix Sangusorbae extract is：After the extract that will be prepared is crushed, volume integral is added
Number filters for 30% ethanol solution；Then it is placed in after filtered fluid is concentrated on large pore resin absorption column, uses same volume fraction
Ethanol solution elution after, dry and obtain the extract.
Embodiment 5
The present invention skin whitening, moisturizing fermentation Chinese wolfberry fruit liquid level film, by weight, including composition it is as follows：
35 parts of pure water；
30 parts of fermentation Chinese wolfberry fruit liquid；
4 parts of polyglutamic acid；Molecular weight is 1,010,000
0.4 part of vitamin C；
18 parts of asparagus juice；
13 parts of pearl powder；The particle diameter of pearl powder is 100nm；
0.6 part of propane diols；
4 parts of chitosan oligomer；Molecular weight is 1400；
6 parts of ganoderma lucidum fermented liquid；
5 parts of Radix Sangusorbae extract；
2 parts of angelica extract；
5 parts of pulullan polysaccharide；Molecular weight is 300,000；
The preparation method of the skin whitening, moisturizing fermentation Chinese wolfberry fruit liquid level film of the present invention, comprises the following steps：In prepared by matrimony vine facial mask
The addition of each component is identical with the parts by weight of each component in above-mentioned matrimony vine facial mask；
(1) polyglutamic acid and pearl powder are dissolved in pure water, and stirred, stir speed (S.S.) is 95r/min, make its into
For thick liquid；
(2) asparagus juice is added in aforesaid liquid, sequentially adds vitamin C, propane diols, pulullan polysaccharide and matrimony vine
Zymotic fluid, chitosan oligomer, ganoderma lucidum fermented liquid, Radix Sangusorbae extract and angelica extract are stirred and evenly mixed, and stir speed (S.S.) is 95r/
Min, obtains facial mask stoste；Ganoderma lucidum fermented liquid is identical with the preparation method of fermentation Chinese wolfberry fruit liquid.
(3) after facial mask stoste is sterilized, then spunlace non-woven cloth Face film towel soaked into 38min, Ran Houzhen in facial mask stoste
Sky encapsulation, is made matrimony vine facial mask.
Wherein fermentation Chinese wolfberry fruit liquid and preparation method thereof is as follows：By dry wolfberry and water in mass ratio 1:15 mixing fully mashing, as
Basal liquid, following percentage by weight material is added into basal liquid：Yeast extract 0.4%, dipotassium hydrogen phosphate 0.2%, sulfuric acid
Magnesium 0.2%, Triammonium citrate 0.2%, manganese sulfate 0.005% sterilizes, inoculating lactic acid bacterium is placed on shaking table after fully mixing
180rpm, cultivates 48h, obtains fermentation Chinese wolfberry fruit stoste by 30 DEG C；By the fermenation raw liquid filtration sterilization, retain supernatant and by supernatant
The pH value of liquid is adjusted to neutrality, obtains fermentation Chinese wolfberry fruit liquid.Lactic acid bacteria is CGMCC NO.1.1 lactic acid bacterias.
The extracting method of angelica extract and Radix Sangusorbae extract is：After the extract that will be prepared is crushed, volume integral is added
Number filters for 95% ethanol solution；Then it is placed in after filtered fluid is concentrated on large pore resin absorption column, uses same volume fraction
Ethanol solution elution after, dry and obtain the extract.
Embodiment 6
The present invention skin whitening, moisturizing fermentation Chinese wolfberry fruit liquid level film, by weight, including composition it is as follows：
30 parts of pure water；
28 parts of fermentation Chinese wolfberry fruit liquid；
3 parts of polyglutamic acid；The molecular weight of polyglutamic acid is 950,000
0.4 part of vitamin C；
16 parts of asparagus juice；
12 parts of pearl powder；
0.5 part of propane diols；
3 parts of chitosan oligomer；Molecular weight is 1600；
8 parts of ganoderma lucidum fermented liquid；
5 parts of Radix Sangusorbae extract；
2 parts of angelica extract；
5 parts of pulullan polysaccharide；The molecular weight of pulullan polysaccharide is 300,000；
The preparation method of the skin whitening, moisturizing fermentation Chinese wolfberry fruit liquid level film of the present invention, comprises the following steps：In prepared by matrimony vine facial mask
The addition of each component is identical with the parts by weight of each component in above-mentioned matrimony vine facial mask；
(1) polyglutamic acid and pearl powder are dissolved in pure water, and stirred, stir speed (S.S.) is 95r/min, make its into
For thick liquid；
(2) asparagus juice is added in aforesaid liquid, sequentially adds vitamin C, propane diols, pulullan polysaccharide and matrimony vine
Zymotic fluid, chitosan oligomer, ganoderma lucidum fermented liquid, Radix Sangusorbae extract and angelica extract are stirred and evenly mixed, and stir speed (S.S.) is 95r/
Min, obtains facial mask stoste；Ganoderma lucidum fermented liquid is identical with the preparation method of fermentation Chinese wolfberry fruit liquid.
(3) after facial mask stoste is sterilized, then spunlace non-woven cloth Face film towel soaked into 38min, Ran Houzhen in facial mask stoste
Sky encapsulation, is made matrimony vine facial mask.
Wherein fermentation Chinese wolfberry fruit liquid and preparation method thereof is as follows：By dry wolfberry and water in mass ratio 1:15 mixing fully mashing, as
Basal liquid, following percentage by weight material is added into basal liquid：Yeast extract 0.4%, dipotassium hydrogen phosphate 0.2%, sulfuric acid
Magnesium 0.2%, Triammonium citrate 0.2%, manganese sulfate 0.005% sterilizes, inoculating lactic acid bacterium is placed on shaking table after fully mixing
180rpm, cultivates 48h, obtains fermentation Chinese wolfberry fruit stoste by 30 DEG C；By the fermenation raw liquid filtration sterilization, retain supernatant and by supernatant
The pH value of liquid is adjusted to neutrality, obtains fermentation Chinese wolfberry fruit liquid.Lactic acid bacteria is CGMCC NO.1.1 lactic acid bacterias.
The extracting method of angelica extract and Radix Sangusorbae extract is：After the extract that will be prepared is crushed, volume integral is added
Number filters for 40% ethanol solution；Then it is placed in after filtered fluid is concentrated on large pore resin absorption column, uses same volume fraction
Ethanol solution elution after, dry and obtain the extract.
Comparative example 1
A kind of skin whitening, moisturizing fermentation Chinese wolfberry fruit liquid level film, its skin whitening, moisturizing fermentation Chinese wolfberry fruit liquid level film prepared with embodiment 6
Difference, which is only that, does not contain ganoderma lucidum fermented liquid.
Comparative example 2
A kind of skin whitening, moisturizing fermentation Chinese wolfberry fruit liquid level film, its skin whitening, moisturizing fermentation Chinese wolfberry fruit liquid level film prepared with embodiment 6
Difference, which is only that, does not contain fermentation Chinese wolfberry fruit liquid.
Comparative example 3
A kind of skin whitening, moisturizing fermentation Chinese wolfberry fruit liquid level film, its skin whitening, moisturizing fermentation Chinese wolfberry fruit liquid level film prepared with embodiment 6
Difference, which is only that, does not contain polyglutamic acid.
Performance detection
Rationally, property is stable for the face pack prescription for the skin whitening, moisturizing function that the present invention is provided, action temperature and no skin irritatin
Property, and by the synergy of various active ingredients, the effects such as with significant skin whitening, moisturizing；
First, human skin patch
With reference to the Ministry of Public Health《Cosmetics health specification》In (version in 2007) related request of " human skin patch " and
Method carries out " human body skin enclosed type patch test ".
1st, given the test agent：The facial mask stoste that the embodiment of the present invention 6, comparative example 1-3 are prepared.
2nd, test method：The volunteer that selection 140 meets inclusion criteria participates in experiment, is randomly divided into 4 groups, every group 35
People.From 4 layers of 1cm2The gauze facial mask stoste of size is soaked, and gauze is pasted on into trial volunteer with non-stimulated adhesive tape cloth
The bent side of forearm, gently pressed with palm and be allowed to equably be pasted on skin, tested material spot examination device is removed after 24h, respectively at
Dermoreaction is observed after 30min, 2h, 4h, 24h and 48h, according to《Skin adverse reaction grade scale table》Record reaction result.
3rd, result of the test：Embodiment 6, the result of the test of all trial volunteers of comparative example 1-3 groups are negative findings, by
This can determine that the facial mask of skin whitening, moisturizing function prepared by the embodiment of the present invention 6, comparative example 1-3 is without skin adverse reaction, security
It is high.
2nd, the inhibition experiment of tyrosinase
2.1 treatment groups (the facial mask stoste that EXAMPLE Example 6, comparative example 1-3 are prepared).
1mL facial mask stostes, 0.9mL pH=6.8 phosphate buffer and 1mL 0.03% tyrosinase in test tube,
It is placed in 37 DEG C of thermostat 10 minutes, adds 0.1mL (1070units/mL) tyrosinase aqueous solution, solution is mixed equal
It is even, it is placed in constant temperature water bath and reacts 25 minutes, its 475nm absorbance A is measured with spectrophotometric.
2.2 blank group
Tyrosinase is replaced with isometric phosphate buffer, its absorbance B is surveyed.
2.3 control group
Facial mask stoste is replaced with isometric distilled water, its absorbance C is surveyed.
2.4 total blank groups
Facial mask stoste is replaced with isometric distilled water, tyrosinase is replaced with isometric phosphate buffer, its suction is surveyed
Luminosity D.
Inhibiting rate (%)=[(C-D)-(A-B)]/(C-D) × 100%, the results are shown in Table 2.
The inhibition of the embodiment 6 of table 1 and comparative example 1-3 group tyrosinases
3rd, radicals scavenging experimental result
3.1 experimental principle
After skin cell is oxidized, a kind of harmful substance can be produced free radical to encroach on skin, when there is radicals scavenging
In the presence of agent, absorb its due to being matched with its unimolecule and disappear, the electron amount that its fading extent receives with it is into quantitatively
Relation, thus available spectrophotometer carries out quick quantitative analysis.
3.2 test method
3.2.1 treatment group
A certain amount of Chinese medicine extract and a certain amount of ethanol solution is gone to make both volume sums be 1mL, with
2mLDPPH free radicals are sufficiently mixed uniformly, stand 30 minutes, and absorbance A at 517nm is measured with spectrophotometric.
3.2.2 treatment group
Extract solution is replaced with distilled water, its absorbance B is surveyed.
Clearance rate (%)=(B-A)/B*100%, the results are shown in Table 3.
The radicals scavenging experiment effect of the embodiment 6 of table 2 and comparative example 1-3 groups
4th, sensory evaluation
1st, given the test agent：The facial mask stoste that the embodiment of the present invention 6, comparative example 1-3 are prepared.
2nd, test method：The volunteer that selection 140 meets inclusion criteria participates in experiment, is randomly divided into 4 groups, every group 35
People, each 35 people of embodiment 6, comparative example 1-3 groups.Each group trial volunteer tries out above-mentioned given the test agent respectively, continuous to use one
Month, try out after terminating, the using effect such as each trial volunteer this self-assessment moisturizing, whitening, sun-proof, overall assessment is done sense organ and commented
Valency, according to using effect in a 0-10/marking, 9-10 points are fine, and 7-8 points are preferable, and 5-6 points are general, and 3-4 points are
Poor, 1-2 points are very poor, are averaged.
3rd, result of the test：It is shown in Table 3.
The skin whitening, moisturizing effect assessment of the embodiment 6 of table 3 and comparative example 1-3 groups
| Group | Embodiment 1 | Comparative example 1 | Comparative example 2 | Comparative example 3 |
| Moistening effect | 9.0 | 8.5 | 8.4 | 8.0 |
| Whitening effect | 8.5 | 8.3 | 8.3 | 8.3 |
| Clearly without greasy feeling | 9.0 | 8.9 | 8.9 | 9.0 |
| Assimilation effect | 8.9 | 8.9 | 8.9 | 8.9 |
| Overall assessment | 9.0 | 8.5 | 8.3 | 8.2 |
As can be known from the results of Table 3, the degree of recognition of the facial mask of skin whitening, moisturizing function prepared by the embodiment of the present invention 6 is high, uses
Effect assessment is high.Significantly, after use, skin is salubrious for the skin whitening, moisturizing fermentation Chinese wolfberry fruit liquid level film repairing effect that the present invention is prepared
Without greasy feeling, good absorbing effect.Continuously using after one month, the phenomenon such as trial volunteer's dry skin, epidermal pigment calmness is bright
It is aobvious to improve.In process of the test, trial volunteer is without allergy or other skin adverse reactions.The whitening that contrast 1-3 is prepared
The using effect of moisturizing fermentation Chinese wolfberry fruit liquid level film is not so good as the reparation facial mask that embodiment 6 is prepared.
Above content is to combine specific preferred embodiment further description made for the present invention, it is impossible to assert
The specific implementation of the present invention is confined to these explanations.For general technical staff of the technical field of the invention,
On the premise of not departing from present inventive concept, some simple deduction or replace can also be made, should all be considered as belonging to the present invention's
Design.
Claims (10)
1. a kind of skin whitening, moisturizing fermentation Chinese wolfberry fruit liquid level film, it is characterized in that：The skin whitening, moisturizing fermentation Chinese wolfberry fruit liquid level film includes spun lacing
The facial mask stoste of non-woven fabrics Face film towel and infiltration on spunlace non-woven cloth；The facial mask stoste includes the group of following parts by weight
Point：
25-40 parts of pure water；
20-35 parts of fermentation Chinese wolfberry fruit liquid；
2-4 parts of polyglutamic acid；
0.3-0.5 parts of vitamin C；
15-20 parts of asparagus juice；
10-15 parts of pearl powder；
0.3-0.8 parts of propane diols；
2-5 parts of chitosan oligomer；
5-10 parts of ganoderma lucidum fermented liquid；
3-6 parts of Radix Sangusorbae extract；
1-3 parts of angelica extract；
3-7 parts of pulullan polysaccharide；
The molecular weight of the polyglutamic acid is 91-101 ten thousand.
2. skin whitening, moisturizing fermentation Chinese wolfberry fruit liquid level film according to claim 1, it is characterised in that point of the chitosan oligomer
Son amount is 1300-1600；Fermentation Chinese wolfberry fruit liquid is lycium ruthenicum zymotic fluid.
3. skin whitening, moisturizing fermentation Chinese wolfberry fruit liquid level film according to claim 1, it is characterised in that the fermentation Chinese wolfberry fruit liquid and spirit
The lactic acid bacteria that sesame zymotic fluid is used when fermenting is CGMCC NO.1.1 lactic acid bacterias.
4. skin whitening, moisturizing fermentation Chinese wolfberry fruit liquid level film according to claim 1, it is characterised in that the particle diameter of the pearl powder is
100-200nm；The molecular weight of the pulullan polysaccharide is 20-40 ten thousand.
5. according to any described skin whitening, moisturizing fermentation Chinese wolfberry fruit liquid level film of claim 1, it is characterised in that the facial mask stoste bag
Include the component of following parts by weight：30 parts of pure water, 28 parts of fermentation Chinese wolfberry fruit liquid, 3 parts of polyglutamic acid, 0.4 part of vitamin C, aloe
16 parts of juice, 12 parts of pearl powder, 0.5 part of propane diols, 3 parts of chitosan oligomer, 8 parts of ganoderma lucidum fermented liquid, 5 parts of Radix Sangusorbae extract, Radix Angelicae Sinensis
5 parts of 2 parts of extract and pulullan polysaccharide；The molecular weight of the polyglutamic acid is 950,000.
6. the preparation method of the skin whitening, moisturizing fermentation Chinese wolfberry fruit liquid level film as described in claim 1-5 is any, it is characterized in that, including with
Lower step：
（1）Polyglutamic acid and pearl powder are dissolved in pure water, and stirred, thick liquid is become；
（2）Asparagus juice is added in aforesaid liquid, vitamin C, propane diols, pulullan polysaccharide and fermentation Chinese wolfberry fruit is sequentially added
Liquid, chitosan oligomer, ganoderma lucidum fermented liquid, Radix Sangusorbae extract and angelica extract are stirred and evenly mixed, and obtain facial mask stoste；
（3）Soaked after the sterilizing of facial mask stoste, then by spunlace non-woven cloth Face film towel in facial mask stoste, then Vacuum Package, system
Obtain matrimony vine facial mask.
7. the preparation method of skin whitening, moisturizing fermentation Chinese wolfberry fruit liquid level film according to claim 6, it is characterised in that：By dry wolfberry
With water in mass ratio 1:The abundant mashing of 8-15 mixing, based on liquid, following percentage by weight material is added into basal liquid：Ferment
Female extract 0.1-0.4%, dipotassium hydrogen phosphate 0.03-0.2%, magnesium sulfate 0.01-0.2%, Triammonium citrate 0.1-0.2%, sulfuric acid
Manganese 0.001-0.005%, sterilizes after fully mixing, inoculating lactic acid bacterium, is placed in 180rpm on shaking table, 30 DEG C, cultivates 48h, obtain Chinese holly
Qi fermenation raw liquid；By the fermenation raw liquid filtration sterilization, retain supernatant and the pH value of supernatant is adjusted to neutrality, obtain matrimony vine hair
Zymotic fluid.
8. the preparation method of skin whitening, moisturizing fermentation Chinese wolfberry fruit liquid level film according to claim 6, it is characterised in that：Step（1）
Or step（2）The stir speed (S.S.) used during middle stirring is 80-100r/min；Step（3）The time of middle immersion is 30-40min.
9. the preparation method of the skin whitening, moisturizing fermentation Chinese wolfberry fruit liquid level film according to claim 6 or 7, it is characterised in that：Ganoderma lucidum
Zymotic fluid is identical with the preparation method of fermentation Chinese wolfberry fruit liquid.
10. the preparation method of skin whitening, moisturizing fermentation Chinese wolfberry fruit liquid level film according to claim 6, it is characterised in that：Radix Angelicae Sinensis is carried
The extracting method for taking thing and Radix Sangusorbae extract is：After the extract that will be prepared is crushed, the second that volume fraction is 30%-95% is added
Alcoholic solution is filtered；Then it is placed on large pore resin absorption column, is washed with the ethanol solution of same volume fraction after filtered fluid is concentrated
After de-, dry and obtain the extract.
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| CN108542825A (en) * | 2018-05-30 | 2018-09-18 | 宁夏凤仪堂生物医药有限公司 | Lycium ruthenicum zymotic fluid and preparation process and the application in cosmetics |
| CN109077954A (en) * | 2018-08-06 | 2018-12-25 | 佗鹊堂国投生物科技股份有限公司 | Cordyceps sinensis facial mask |
| CN109966236A (en) * | 2019-04-17 | 2019-07-05 | 曲嫣红 | A kind of U.S. flesh bacterium probiotics and the preparation method and application thereof |
| WO2020062388A1 (en) * | 2018-09-28 | 2020-04-02 | 温伟成 | Xinhui citrus flower extract liquor-based formula and process for preparing facial mask |
| CN112245648A (en) * | 2020-10-30 | 2021-01-22 | 广州润虹医药科技股份有限公司 | Anti-inflammatory and antibacterial hydrocolloid oily yarn and preparation method thereof |
| CN114632053A (en) * | 2022-04-28 | 2022-06-17 | 浙江长生鸟健康科技股份有限公司 | Pearl powder-enhanced antioxidant ganoderma sinensis crude extract and fermentation method thereof |
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