CN107259087A - A kind of disease-resistant Chinese herbal feed additive and preparation method thereof - Google Patents

A kind of disease-resistant Chinese herbal feed additive and preparation method thereof Download PDF

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Publication number
CN107259087A
CN107259087A CN201710556438.1A CN201710556438A CN107259087A CN 107259087 A CN107259087 A CN 107259087A CN 201710556438 A CN201710556438 A CN 201710556438A CN 107259087 A CN107259087 A CN 107259087A
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parts
disease
feed additive
chinese herbal
herbal feed
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张松波
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/30Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/66Papaveraceae (Poppy family), e.g. bloodroot
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/85Verbenaceae (Verbena family)

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Molecular Biology (AREA)
  • Physiology (AREA)
  • Animal Husbandry (AREA)
  • Zoology (AREA)
  • Food Science & Technology (AREA)
  • Fodder In General (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention belongs to field of feed additive technology, more particularly to a kind of disease-resistant Chinese herbal feed additive is made up of the raw material of following parts by weight:30 60 parts of gold boiling grass, 15 25 parts of radix ranunculi ternati, 10 20 parts of decumbent corydalis tuber, 8 20 parts of fruit of negundo, 5 15 parts of belladonna (herb), 15 parts of fennelflower seed, 15 parts of Calusena lansium core.The present invention also provides the preparation method of disease-resistant Chinese herbal feed additive.Disease-resistant Chinese herbal feed additive of the invention is prepared using the inventive method, it is possible to increase its disease-resistant effect, reduce the death rate.

Description

A kind of disease-resistant Chinese herbal feed additive and preparation method thereof
Technical field
The invention belongs to field of feed additive technology, more particularly to a kind of disease-resistant Chinese herbal feed additive and its preparation side Method.
Background technology
With the continuous improvement of human living standards, craving of the people to pollution-free food is increasing.Poultry and livestock are The main source of nutriment on people's dining table, its security receives great attention.In order to improve its yield and quality, raising Some beneficial materials are added in material as an effective approach.The main purpose of feed addictive is to provide battalion to animal Support, promote growth, improve reproductive capacity, and strengthen immunity, disease preventing and treating.
But the toxic action of most of chemical feed additives is attract attention at present, antibiotic, hormone, change Residual caused by synthetic drug is learned, the resistance to the action of a drug, " three (causing teratogenesis, carcinogenic, mutagenesis) " has seriously threatened the health of people, in recent years Chemical addition agent is limited the use of or disabled to have multiple countries, and Chinese medicine is then small with its toxic side effect, residual is few, have no drug resistance and can The characteristics of disease preventing and treating, as the important source material for improving or substituting chemical addition agent.
The content of the invention
The technical problems to be solved by the invention are to provide a kind of disease-resistant Chinese herbal feed additive, and the additive can be notable Improve the resistance against diseases of domestic animals.
To achieve the above object, the present invention is adopted the following technical scheme that:
A kind of disease-resistant Chinese herbal feed additive, is made up of the raw material of following parts by weight:Gold 30-60 parts of grass of boiling, radix ranunculi ternati 15- 25 parts, 10-20 parts of decumbent corydalis tuber, 8-20 parts of fruit of negundo, 5-15 parts of belladonna (herb), 1-5 parts of fennelflower seed, 1-5 parts of Calusena lansium core.
Preferably, disease-resistant Chinese herbal feed additive of the present invention, is made up of the raw material of following parts by weight:Gold boiling grass 45 Part, 20 parts of radix ranunculi ternati, 15 parts of decumbent corydalis tuber, 14 parts of fruit of negundo, 10 parts of belladonna (herb), 3 parts of fennelflower seed, 3 parts of Calusena lansium core.
The present invention also provides the preparation method of disease-resistant Chinese herbal feed additive, including following preparation process:
1) raw material is weighed by weight, is well mixed;
2) 2-4 times of water of whole raw material weights is added, is boiled, fluidized state 3-6min is kept, is cooled to room temperature;
3) again by the raw material after decoction at 28-35 DEG C sealing and fermenting 2-5 days;
4) fermentate is dried, crushing.
Preferably, in the inventive method, the step 2) in, slow fire keeps fluidized state.
Preferably, in the inventive method, the step 3) in, the sealing and fermenting at 33 DEG C.
Preferably, in the inventive method, the step 4) in, dried at 50-60 DEG C.
Preferably, in the inventive method, the step 4) in, it is crushed to 150-250 mesh.
In the raw material of the present invention:
Gold boiling grass, feverfew Inula britannica chinensis lnula japonica Thunb. aerial part.It is warm-natured, it is bitter, pungent, salty. Sending down abnormally ascending, resolving sputum, water-filling.Belong to the medicine for warming and resolving cold-phlegm of expectorants, antitussives and anti-asthmatics medicine subordinate classification.
Radix ranunculi ternati, ranunculaceae plant Seynuns Kugelann Ranunculus ternatus Thunb. dried root.It is warm-natured, taste It is sweet, pungent.Dissipating bind, removing toxic substances, detumescence.Belong to the medicine for warming and resolving cold-phlegm of expectorants, antitussives and anti-asthmatics medicine subordinate classification.
Decumbent corydalis tuber, bloodroot lies prostrate raw corydalis Corydatis decumbens (Thunb.) Pers. stem tuber.It is warm-natured, Bitter, micro-pungent.Promoting blood circulation, dredging collateral, promoting qi circulation and relieving pain.Belong to the blood-activating analgesic of drug for invigorating blood circulation and eliminating stasis subordinate classification.
Fruit of negundo, Verbenaceae five-leaved chaste tree Viter negundo L. fruit.It is warm-natured, pungent, hardship.Expel pathogenic wind from the body surface, Preventing phlegm from forming and stopping coughing, promoting qi circulation and relieving pain.Belong to the warm-pungent diaphoretic drug of diaphoretic medicine subordinate classification.
Belladonna (herb), plant of Solanaceae belladonna Atropa belladonnaL. herb.Mildly bitter flavor, pungent, gas is micro-.Relieving spasm and pain, Suppress secretion.Modern Chinese herbal medicine.
Fennelflower seed, ranunculaceae plant Semen Nigellae Nigella glandulifera Freyn dry mature seed (Uygur nationality's common medicine).It is warm-natured, it is sweet, pungent.Kidney-tonifying and brain tonic, stimulates the menstrual flow, promoting lactation, diuresis.Belong to damp-clearing drug subordinate classification Stranguria-relieving diuretic.
Calusena lansium core, rutaceae Calusena lansium Clausena lansium (Lour.) Skeels. seed.Slightly warm in nature, taste Pungent, hardship.Qi-regulating helps digestion, dissipating bind dissipate-swelling, preventing phlegm from forming and stopping coughing.Belong to qi-regulating drug.
The disease-resistant Chinese herbal feed additive of the present invention may be used in any poultry and livestock feed, in use, by feed relative 0.02-0.1% amount proportioning is added.
Compared with prior art, the beneficial effects of the present invention are:
1st, gold boiling grass, radix ranunculi ternati, decumbent corydalis tuber, fruit of negundo, belladonna (herb), fennelflower seed and Calusena lansium caryogamy in the inventive method 5, it is applicable in whole bird feed additives, plays disease-resistant effect.
2nd, prepare additive using the inventive method, it is possible to increase its disease-resistant effect, reduce the death rate.
3rd, in raw material of the present invention, using Chinese medicine material, toxic side effect is small, and raw material is easy to get, and additive cost is low.
Embodiment
The invention will be further described with reference to embodiments, but the invention is not limited in these embodiments.
Embodiment 1
1) raw material is weighed by following parts by weight:30 parts of gold boiling grass, 25 parts of radix ranunculi ternati, 10 parts of decumbent corydalis tuber, 20 parts of fruit of negundo, top 5 parts of eggplant grass, 5 parts of fennelflower seed, 1 part of Calusena lansium core is well mixed;
2) 2 times of water of whole raw material weights are added, are boiled, slow fire keeps fluidized state 3min, is cooled to room temperature;
3) again by the raw material after decoction at 35 DEG C sealing and fermenting 2 days;
4) drying at 60 DEG C by fermentate, is crushed to 150 mesh, you can.
Embodiment 2
1) raw material is weighed by following parts by weight:35 parts of gold boiling grass, 23 parts of radix ranunculi ternati, 12 parts of decumbent corydalis tuber, 17 parts of fruit of negundo, top 7 parts of eggplant grass, 4 parts of fennelflower seed, 2 parts of Calusena lansium core is well mixed;
2) 4 times of water of whole raw material weights are added, are boiled, slow fire keeps fluidized state 4min, is cooled to room temperature;
3) again by the raw material after decoction at 34 DEG C sealing and fermenting 3 days;
4) drying at 58 DEG C by fermentate, is crushed to 180 mesh, you can.
Embodiment 3
1) raw material is weighed by following parts by weight:45 parts of gold boiling grass, 20 parts of radix ranunculi ternati, 15 parts of decumbent corydalis tuber, 14 parts of fruit of negundo, top 10 parts of eggplant grass, 3 parts of fennelflower seed, 3 parts of Calusena lansium core is well mixed;
2) 3 times of water of whole raw material weights are added, are boiled, slow fire keeps fluidized state 5min, is cooled to room temperature;
3) again by the raw material after decoction at 32 DEG C sealing and fermenting 4 days;
4) drying at 55 DEG C by fermentate, is crushed to 200 mesh, you can.
Embodiment 4
1) raw material is weighed by following parts by weight:50 parts of gold boiling grass, 18 parts of radix ranunculi ternati, 18 parts of decumbent corydalis tuber, 11 parts of fruit of negundo, top 12 parts of eggplant grass, 2 parts of fennelflower seed, 4 parts of Calusena lansium core is well mixed;
2) 3 times of water of whole raw material weights are added, are boiled, slow fire keeps fluidized state 6min, is cooled to room temperature;
3) again by the raw material after decoction at 30 DEG C sealing and fermenting 5 days;
4) drying at 53 DEG C by fermentate, is crushed to 230 mesh, you can.
Embodiment 5
1) raw material is weighed by following parts by weight:60 parts of gold boiling grass, 15 parts of radix ranunculi ternati, 20 parts of decumbent corydalis tuber, 8 parts of fruit of negundo, top 15 parts of eggplant grass, 1 part of fennelflower seed, 5 parts of Calusena lansium core is well mixed;
2) 2 times of water of whole raw material weights are added, are boiled, slow fire keeps fluidized state 3min, is cooled to room temperature;
3) again by the raw material after decoction at 28 DEG C sealing and fermenting 4 days;
4) drying at 50 DEG C by fermentate, is crushed to 250 mesh, you can.
Comparative example 1
Raw material is weighed by following parts by weight:45 parts of gold boiling grass, 20 parts of radix ranunculi ternati, 15 parts of decumbent corydalis tuber, 14 parts of fruit of negundo, belladonna 10 parts of grass, 3 parts of fennelflower seed, 3 parts of Calusena lansium core is well mixed, is crushed to 200 mesh.
Comparative example 2
1) raw material is weighed by following parts by weight:45 parts of gold boiling grass, 20 parts of radix ranunculi ternati, 15 parts of decumbent corydalis tuber, 14 parts of fruit of negundo, top 10 parts of eggplant grass, 3 parts of fennelflower seed, 3 parts of Calusena lansium core is well mixed;
2) 3 times of water of whole raw material weights, sealing and fermenting 4 days at 32 DEG C are added;
3) drying at 55 DEG C by fermentate, is crushed to 200 mesh, you can.
Test example
1st, experimental animal
Experiment 1 week old broiler chicken of selection, is randomly divided into 4 test groups, every group 70, respectively A, B, C, D, and the cultivation phase is 40 My god;Wherein:
Daily ration based on A groups, conventional feed;
B groups are the additive for the embodiment of the present invention 3 that its weight 0.06% is added into basal diet;
C groups are the additive for the comparative example 1 that its weight 0.06% is added into basal diet;
D groups are the additive for the comparative example 2 that its weight 0.06% is added into basal diet.
2nd, feeding management and index determining
All test chickens are raised in same hen house, and immune programme for children and feeding and management method are carried out in the usual way.Day Feed 2 times, doses is sufficient, free water, longitudinal ventilation fan, daily illumination 16 hours, 3~4 watts of every cubic metre of illumination.Scrape daily Excrement 1 time.Testing index is:Production performance index (feed conversion rate), diarrhea disease percentage, the death rate, Immune Organs Index.Its In:
1) broiler fodder conversion ratio experiment Id and 40d, the weight for every chicken of being weighed on an empty stomach before noon is fed with for every 10 days Amount, calculates average daily gain (ADG), settles accounts remaining material, calculates average feed intake (ADFI).Feed conversion rate=ADFI:ADG, Calculate 40 days accumulation feed conversion rates.
2) broiler chicken diarrhea disease percentage diarrhoea judges to use excrement index, 1 point:Normally, there are good profile and hardness, bar shaped Point:Normally, soft excrement, in heap-type point:Compare dilute soft, flat-shaped, water content is big, but without liquid dung separation point:The watery stools flashed. Excrement index more than 3 is determined as diarrhoea, the diarrhea disease percentage of each group chicken during statistics feeding.
Diarrhea disease percentage=(total diarrhoea head number/experiment head number) * 100%
3) death rate of each group chicken during broiler chicken mortality statistics is fed.
The death rate=(dead chicken number/experimental chicken number) * 100%
4) after the experiment of broiler chicken Immune Organs Index terminates, every group of chicken randomly selects 10, weighs on an empty stomach, and spleen is separated after slaughtering Dirty, thymus gland, the bursa of farbricius, its weighed weight, Computation immunity shoot formation.
Immune Organs Index=(Organs Weight/live body chicken weight) * 100%
3rd, result of the test
The influence of the Additive On Chickens feed conversion rate of the present invention of table 1, diarrhea disease percentage and the death rate
Group Feed conversion rate Diarrhea disease percentage/% The death rate
A groups 1.61±0.05 12.86±0.16 11.43±0.31
B groups 2.21±0.18 1.43±0.68 4.29±0.28
C groups 1.75±0.09 7.14±0.56 7.14±0.36
D groups 1.86±0.28 5.71±0.36 7.14±0.36
The influence of the Additive On Chickens Immune Organs Index of the present invention of table 2

Claims (7)

1. a kind of disease-resistant Chinese herbal feed additive, it is characterised in that be made up of the raw material of following parts by weight:Gold 30-60 parts of grass of boiling, 15-25 parts of radix ranunculi ternati, 10-20 parts of decumbent corydalis tuber, 8-20 parts of fruit of negundo, 5-15 parts of belladonna (herb), 1-5 parts of fennelflower seed, Calusena lansium core 1-5 Part.
2. disease-resistant Chinese herbal feed additive according to claim 1, it is characterised in that by the raw material system of following parts by weight Into:45 parts of gold boiling grass, 20 parts of radix ranunculi ternati, 15 parts of decumbent corydalis tuber, 14 parts of fruit of negundo, 10 parts of belladonna (herb), 3 parts of fennelflower seed, Calusena lansium core 3 Part.
3. the preparation method of disease-resistant Chinese herbal feed additive according to claim 1 or 2, it is characterised in that including following Preparation process:
1) raw material is weighed by weight, is well mixed;
2) 2-4 times of water of whole raw material weights is added, is boiled, fluidized state 3-6min is kept, is cooled to room temperature;
3) again by the raw material after decoction at 28-35 DEG C sealing and fermenting 2-5 days;
4) fermentate is dried, crushing.
4. the preparation method of disease-resistant Chinese herbal feed additive according to claim 3, it is characterised in that:The step 2) In, slow fire keeps fluidized state.
5. the preparation method of disease-resistant Chinese herbal feed additive according to claim 3, it is characterised in that:The step 3) In, the sealing and fermenting at 33 DEG C.
6. the preparation method of disease-resistant Chinese herbal feed additive according to claim 3, it is characterised in that:The step 4) In, dried at 50-60 DEG C.
7. the preparation method of disease-resistant Chinese herbal feed additive according to claim 3, it is characterised in that:The step 4) In, it is crushed to 150-250 mesh.
CN201710556438.1A 2017-07-10 2017-07-10 A kind of disease-resistant Chinese herbal feed additive and preparation method thereof Pending CN107259087A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108783076A (en) * 2018-06-28 2018-11-13 浦北县清华生态养鸡专业合作社 Prevent the preparation method of chicken colibacillosis feed

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Publication number Priority date Publication date Assignee Title
CN103609909A (en) * 2013-12-04 2014-03-05 晋江市英威特生物技术有限公司 Pollution-free aquatic feed additive using ginkgo leaves as base stock
CN104187024A (en) * 2014-07-07 2014-12-10 芜湖诚德农业科技有限公司 Fragrant pig feed
CN105124209A (en) * 2015-08-13 2015-12-09 济南和美华动物营养品有限公司 Concentrated feed for milking sows, capable of improving production performance of milking sows
CN105707517A (en) * 2016-03-07 2016-06-29 怀远县渔业科技发展有限责任公司 Preparation method of additive special for artificial breeding feed of Euchiloglanis kishinouyei Kimura
CN106376742A (en) * 2016-08-29 2017-02-08 天峨县全盛蜂业科技有限公司 Pig traditional Chinese medicine feed additive for growth promotion
CN106615705A (en) * 2016-12-05 2017-05-10 全椒县城西畜牧养殖专业合作社 High-quality layer feed

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103609909A (en) * 2013-12-04 2014-03-05 晋江市英威特生物技术有限公司 Pollution-free aquatic feed additive using ginkgo leaves as base stock
CN104187024A (en) * 2014-07-07 2014-12-10 芜湖诚德农业科技有限公司 Fragrant pig feed
CN105124209A (en) * 2015-08-13 2015-12-09 济南和美华动物营养品有限公司 Concentrated feed for milking sows, capable of improving production performance of milking sows
CN105707517A (en) * 2016-03-07 2016-06-29 怀远县渔业科技发展有限责任公司 Preparation method of additive special for artificial breeding feed of Euchiloglanis kishinouyei Kimura
CN106376742A (en) * 2016-08-29 2017-02-08 天峨县全盛蜂业科技有限公司 Pig traditional Chinese medicine feed additive for growth promotion
CN106615705A (en) * 2016-12-05 2017-05-10 全椒县城西畜牧养殖专业合作社 High-quality layer feed

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108783076A (en) * 2018-06-28 2018-11-13 浦北县清华生态养鸡专业合作社 Prevent the preparation method of chicken colibacillosis feed

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