CN107250091B - 合成光学活性羰基化合物的方法 - Google Patents

合成光学活性羰基化合物的方法 Download PDF

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Publication number
CN107250091B
CN107250091B CN201580076501.0A CN201580076501A CN107250091B CN 107250091 B CN107250091 B CN 107250091B CN 201580076501 A CN201580076501 A CN 201580076501A CN 107250091 B CN107250091 B CN 107250091B
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alkyl
aryl
unsubstituted
hydrogen
cycloalkyl
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CN107250091A (zh
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M·施尔维斯
R·帕切洛
G·海德里希
G·威格纳
G-D·特贝恩
M·豪布纳
A·凯勒
O·贝
S·伦茨
G·希贝尔
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BASF SE
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/62—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by hydrogenation of carbon-to-carbon double or triple bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/17—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by hydrogenation of carbon-to-carbon double or triple bonds
    • C07C29/172—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by hydrogenation of carbon-to-carbon double or triple bonds with the obtention of a fully saturated alcohol
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/56—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by isomerisation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
CN201580076501.0A 2014-12-19 2015-12-18 合成光学活性羰基化合物的方法 Active CN107250091B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP14199410.3 2014-12-19
EP14199410 2014-12-19
PCT/EP2015/080392 WO2016097242A1 (de) 2014-12-19 2015-12-18 Verfahren zur herstellung optisch aktiver carbonylverbindungen

Publications (2)

Publication Number Publication Date
CN107250091A CN107250091A (zh) 2017-10-13
CN107250091B true CN107250091B (zh) 2021-05-04

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CN201580076501.0A Active CN107250091B (zh) 2014-12-19 2015-12-18 合成光学活性羰基化合物的方法

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US (3) US9975837B2 (cg-RX-API-DMAC10.html)
EP (2) EP3233778B1 (cg-RX-API-DMAC10.html)
JP (1) JP6702974B2 (cg-RX-API-DMAC10.html)
CN (1) CN107250091B (cg-RX-API-DMAC10.html)
ES (2) ES2727384T3 (cg-RX-API-DMAC10.html)
MX (1) MX375969B (cg-RX-API-DMAC10.html)
WO (1) WO2016097242A1 (cg-RX-API-DMAC10.html)

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CN107735392B (zh) 2015-05-04 2021-12-03 巴斯夫欧洲公司 制备甜瓜醛的方法
US10647651B2 (en) 2015-10-12 2020-05-12 Basf Se Hydroformylation process for producing 1,6-disubstituted hexane derivatives
MX2018007068A (es) 2015-12-08 2018-08-01 Basf Se Un material zeolitico con contenido de estaño que tiene una estructura de armazon de bea.
WO2017211784A1 (en) 2016-06-07 2017-12-14 Basf Se Process for preparing 2,3-unsaturated alcohols
MX2018016297A (es) 2016-06-29 2019-09-16 Basf Se Proceso para la preparacion de aldehidos alfa, beta insaturados mediante oxidacion de alcoholes en presencia de una fase liquida.
US10669222B2 (en) 2016-10-06 2020-06-02 Basf Se Process for enriching enantiomers from an enantiomer mixture
BR112020010507A2 (pt) * 2017-12-21 2020-11-10 Basf Se processo para a preparação de aldeídos alfa, beta insaturados
JP7433298B2 (ja) * 2018-09-05 2024-02-19 ビーエーエスエフ ソシエタス・ヨーロピア 気／液二相高圧反応を行う方法
MY205693A (en) 2018-09-05 2024-11-07 Basf Se Reactor for carrying out a gas-liquid two-phase high-pressure reaction with a foaming medium
MY206878A (en) * 2018-09-05 2025-01-12 Basf Se Reactor for carrying out a reaction between two non-miscible fluids of different densities
BR112021001695B1 (pt) * 2018-09-05 2023-12-26 Basf Se Processos para produção contínua de um composto de carbonila e para produzir mentol opticamente ativo
KR102847500B1 (ko) * 2019-05-27 2025-08-20 디에스엠 아이피 어셋츠 비.브이. 인 화합물 및 유기 황 화합물의 존재 하에서의 알킨의 알켄으로의 선택적 수소화
WO2021114021A1 (zh) 2019-12-09 2021-06-17 万华化学集团股份有限公司 一种光学活性的香茅醛的制备方法
CN111056932A (zh) * 2019-12-09 2020-04-24 万华化学集团股份有限公司 一种制备光学活性香茅醛的方法
CN110872217A (zh) * 2019-12-09 2020-03-10 万华化学集团股份有限公司 一种光学活性的香茅醛的制备方法
CN111004102B (zh) * 2019-12-23 2022-11-04 万华化学集团股份有限公司 一种制备光学活性香茅醛的方法及用于该方法的催化剂
CN111056933B (zh) * 2019-12-24 2022-11-08 万华化学集团股份有限公司 一种制备光学活性香茅醛的方法及用于该方法的催化剂体系
CN111792986B (zh) * 2020-07-22 2022-09-20 万华化学集团股份有限公司 一种制备r-香茅醛的方法
CN112142583B (zh) * 2020-10-26 2022-07-26 万华化学集团股份有限公司 一种香叶醛制备橙花醛的方法
CN113527367B (zh) * 2021-07-14 2022-08-02 南开沧州渤海新区绿色化工研究有限公司 一种含四（3,5-二三氟甲基苯基）硼阴离子的手性双膦配体铑络合物和制备方法及应用
CN121443573A (zh) 2023-07-07 2026-01-30 巴斯夫欧洲公司 香叶醛和橙花醛的光异构化
CN118304941A (zh) * 2024-03-22 2024-07-09 江苏极易新材料有限公司 一种2-(2’-羟基-5’-叔辛基苯基)苯并三唑的合成方法

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US4237072A (en) * 1977-07-04 1980-12-02 Rhone-Poulenc Industries Preparation of optically active citronellal
CN101065344A (zh) * 2004-11-26 2007-10-31 巴斯福股份公司 薄荷醇的制备方法
CN101675020A (zh) * 2007-04-25 2010-03-17 巴斯夫欧洲公司 合成光学活性羰基化合物的方法
EP2543437A2 (en) * 2010-03-04 2013-01-09 Takasago International Corporation Homogeneous asymmetric hydrogenation catalyst

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US4123465A (en) * 1975-10-16 1978-10-31 Hoffmann-La Roche Inc. Chiral tertiary phosphines
JPS5278812A (en) 1975-12-26 1977-07-02 Nikki Chem Co Ltd Selective production method of saturated aldehyde
DE19854637A1 (de) 1998-11-26 2000-05-31 Basf Ag Reaktor zur kontinuierlichen Durchführung von Gas-Flüssig-, Flüssig-Flüssig- oder Gas-Flüssig-Fest-Reaktionen
JP4676617B2 (ja) 2001-01-18 2011-04-27 高砂香料工業株式会社 イソプレゴールの製造方法
DE102004049631A1 (de) 2004-10-11 2006-04-20 Basf Ag Verfahren zur Herstellung optisch aktiver Carbonylverbindungen
AR070176A1 (es) * 2008-01-17 2010-03-17 Novartis Ag Procesos de sintesis de inhibidores de nep, compuestos intermediarios y uso de los mismos en la sintesis

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4237072A (en) * 1977-07-04 1980-12-02 Rhone-Poulenc Industries Preparation of optically active citronellal
CN101065344A (zh) * 2004-11-26 2007-10-31 巴斯福股份公司 薄荷醇的制备方法
CN101675020A (zh) * 2007-04-25 2010-03-17 巴斯夫欧洲公司 合成光学活性羰基化合物的方法
EP2543437A2 (en) * 2010-03-04 2013-01-09 Takasago International Corporation Homogeneous asymmetric hydrogenation catalyst

Non-Patent Citations (3)

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Title
"Achiral Ligands Dramatically Enhance Rate and Enantioselectivity in the Rh/Phosphoramidite-Catalyzed Hydrogenation of α,β-Disubstituted Unsaturated Acids";Rob Hoen , Jeroen A. F 等;《Angew. Chem. Int. Ed》;20050623;第44卷;摘要、表1-2 *
"Carbonylhydridotris(triphenyl-phosphine)rhodium(I)";Maree P. Collis & Patrick Perlmutter;《Encyclopedia of Reagents for Organic Synthesis》;20071231;全文 *
"Highly Enantio- and s-trans C=C Bond Selective Catalytic Hydrogenation of Cyclic Enones: Alternative Synthesis of (-)-Menthol";Takashi Ohshima 等;《Chem. Eur. J》;20081231;第14卷;表1 *

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Publication number Publication date
JP6702974B2 (ja) 2020-06-03
US9975837B2 (en) 2018-05-22
CN107250091A (zh) 2017-10-13
JP2017537965A (ja) 2017-12-21
ES2883557T3 (es) 2021-12-09
US20180057437A1 (en) 2018-03-01
USRE49036E1 (en) 2022-04-19
MX375969B (es) 2025-03-06
US20180244598A1 (en) 2018-08-30
US10301244B2 (en) 2019-05-28
EP3233778B1 (de) 2019-02-20
ES2727384T3 (es) 2019-10-15
EP3233778A1 (de) 2017-10-25
MX2017008170A (es) 2017-09-18
EP3489213A1 (de) 2019-05-29
WO2016097242A1 (de) 2016-06-23
EP3489213B1 (de) 2021-04-28

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