CN107233493A - It is a kind of to treat traditional Chinese medicine injection of checken pest and preparation method thereof - Google Patents
It is a kind of to treat traditional Chinese medicine injection of checken pest and preparation method thereof Download PDFInfo
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- CN107233493A CN107233493A CN201710513645.9A CN201710513645A CN107233493A CN 107233493 A CN107233493 A CN 107233493A CN 201710513645 A CN201710513645 A CN 201710513645A CN 107233493 A CN107233493 A CN 107233493A
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- 238000002347 injection Methods 0.000 title claims abstract description 40
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- 238000002360 preparation method Methods 0.000 title claims abstract description 21
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- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
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Abstract
The invention provides a kind of traditional Chinese medicine injection for treating checken pest and preparation method thereof, the traditional Chinese medicine injection is made with ten Chinese medicines such as radix bupleuri, cordate houttuynia, sealwort, barrenwort, selfheal, schizonepeta, rattletop, sweet wormwood, perilla leaf, Radix Isatidis, its Synergistic, the strongly fragrant poison of solution is played altogether, with strong antibiosis and antiviral functions, for treating the sick effect highly significant of checken pest, its cure rate is up to 84%, and it is rapid-action, it is very suitable for checken pest disease, morbidity is unexpected, infect the control of the feature such as fast, and it is uneasy to recur and without any side effects, use safety.
Description
Technical field
The invention belongs to cultural technique field, and in particular to a kind of to treat traditional Chinese medicine injection of checken pest and preparation method thereof.
Background technology
Checken pest is also known as newcastle disease, is the acute, deadly infectious disease as caused by NDV, can cause various age chicken senses
Hair dyeing disease and dead, the disease is still to endanger maximum infectious disease in China's poultry husbandry at present.This disease was without obvious seasonality, 1 year
The four seasons can occur, particularly abrupt seasonal change when be easier induce this disease.Its clinical symptoms is：The anxious chicken that falls ill is more without obvious disease
Shape and die by visitation of God.Morbidity chicken performance spirit is poor in most cases, searches for food and reduces or do not eat, two wings are sagging, slow-witted vertical one side of closing one's eyes,
Mouth breathing, sends snore.Part chicken draws green loose stool.After laying hen infection in addition to there is respiratory symptom, it is mainly shown as
Lay eggs it is unexpected decline, eggshell color shoaled, coarse, and check increases, and feed intake is reduced, and the death rate is typically relatively low.After morbidity
Phase, some diseased chickens are turned one's head, bend neck, the nervous symptoms such as turn-take.
Checken pest mainly includes two types, wherein based on bird flu (European checken pest) and newcastle disease (philippine fowl disease),
Newcastle disease is so that nineteen twenty-six betides Indonesia and gains the name.It is mainly new with chicken for the traditional checken pest of China
Based on the epidemic disease of city, and bird flu disease time is earlier, easily triggers the infection of birds, for a long time, control and pre- avian influenza-prevention
Method is mainly by sterilizing, isolating and slaughter poultry to prevent spreading for bird flu, and have been found in recent years
The bird flu of people is infected, has triggered the highest attention in the world.The prevention and treatment of checken pest, has important shadow for poultry husbandry
Ring, intensive poultry is the main trend of poultry husbandry development, but the influence of checken pest is very huge for the threat of poultry husbandry, is
Effective control and prevention checken pest, there is no specific treatment medicine, make a definite diagnosis and take measures in time in early days, to controlling and disappear at present
Go out and checken pest, reduction economic loss are significant.Traditional prevention and controls are used to chicken using many malicious anti-, malicious excellent products,
But it is chemicals, the requirement of green non-pollution poultry is not met.
The content of the invention
To solve the above problems, the invention provides a kind of traditional Chinese medicine injection for treating checken pest and preparation method thereof, in this
Medicine parenteral solution is made up of radix bupleuri, cordate houttuynia, sealwort, barrenwort, selfheal, schizonepeta, rattletop, sweet wormwood, perilla leaf, Radix Isatidis, its
Drug effect is rapid-action, for treating the sick effect highly significant of checken pest.
Specifically, a kind of traditional Chinese medicine injection for treating checken pest, by weight, by 3-25 parts of radix bupleuri, 3-25 parts of cordate houttuynia,
5-13 parts of sealwort, 5-13 parts of barrenwort, 3-25 parts of selfheal, 3-9 parts of schizonepeta, 3-9 parts of rattletop, 3-25 parts of sweet wormwood, perilla leaf 6-
18 parts, 3-25 parts of Radix Isatidis is made；
Further, a kind of traditional Chinese medicine injection for treating checken pest, by weight, by 8-20 parts of radix bupleuri, cordate houttuynia 8-20
Part, 8-10 parts of sealwort, 8-10 parts of barrenwort, 8-20 parts of selfheal, 5-7 parts of schizonepeta, 5-7 parts of rattletop, 8-20 parts of sweet wormwood, perilla leaf
11-13 parts, 8-20 parts of Radix Isatidis is made；
Yet further, a kind of traditional Chinese medicine injection for treating checken pest, by weight, by 14 parts of radix bupleuri, 14 parts of cordate houttuynia,
9 parts of sealwort, 9 parts of barrenwort, 14 parts of selfheal, 6 parts of schizonepeta, 6 parts of rattletop, 14 parts of sweet wormwood, 12 parts of perilla leaf, 14 parts of systems of Radix Isatidis
Into；
Present invention also offers a kind of preparation method for the traditional Chinese medicine injection for treating checken pest, comprise the following steps：
(1) radix bupleuri, cordate houttuynia, sealwort, barrenwort, selfheal, schizonepeta, rattletop, sweet wormwood, perilla leaf, the plate of above-mentioned amount are taken
Blue root is crushed, plus the 6-8 times of decocting measured boils secondary, 1.5 hours for the first time, and second 1 hour, collecting decoction, filtration, filtrate was standby
With；
(2) above-mentioned filtrate is concentrated into relative density for 1.00-1.05 under conditions of 50 DEG C, adds ethanol to content
Alcohol amount 70%, stirs, filtration；Ethanol is reclaimed with single-action concentration method, same method is handled 2-4 times；Add 1 times of weight
Then ground water for injection, filtration adds the activated carbon decolorizing of filtrate weight 1%, filtration；PH value is adjusted to 8.0- with ammoniacal liquor again
9.0, refrigerated 12-24 hours at 4-0 DEG C, then filtration heats deammoniation, make pH value to 5.0-7.0, standby；
(3) the treated filtrate of step (2) is taken to be filtered again with 0.45 μm of miillpore filter；Embedding, every 3mL, 110-120
DEG C sterilizing, obtain parenteral solution.
Step (1) described above take the radix bupleuri of above-mentioned amount, cordate houttuynia, sealwort, barrenwort, selfheal, schizonepeta, rattletop,
Sweet wormwood, perilla leaf, Radix Isatidis are crushed, plus the decocting of 7 times of amounts boils secondary, 1.5 hours for the first time, second 1 hour, are merged and are decocted
Liquid, filtration, filtrate is standby.
Above-mentioned filtrate is concentrated into relative density for 1.00-1.05 by step (2) described above under conditions of 50 DEG C, then
Ethanol is added to content alcohol amount 70%, is stirred, is filtered；Ethanol is reclaimed with single-action concentration method, same method is handled 3 times；
With adding 1 times of weight water for injection, filtration, then adds the activated carbon decolorizing of filtrate weight 1%, filtration；Adjusted again with ammoniacal liquor
PH value is saved to 8.5, is refrigerated 18 hours at 2 DEG C, then filtration heats deammoniation, make pH value to 6.0, standby.
Step (3) described above takes the treated filtrate of step (2) to be filtered again with 0.45 μm of miillpore filter；Embedding,
Every 3mL, 115 DEG C of sterilizings, obtains parenteral solution.
Traditional Chinese medicine injection of the present invention is in use, be to use administered intramuscular, by i.e. chicken weight 3ml/kg.
The beneficial effects of the present invention are：
The present invention is by studying checken pest pathological characters, using a large amount of screenings to anti virus herb, final to determine
With ten Chinese medicine groups such as radix bupleuri, cordate houttuynia, sealwort, barrenwort, selfheal, schizonepeta, rattletop, sweet wormwood, perilla leaf, Radix Isatidis
Into its Synergistic plays the strongly fragrant poison of solution altogether, and with strong antibiosis and antiviral functions, for treating the sick effect highly significant of checken pest, it is controlled
More rate is and rapid-action up to 84%, is very suitable for checken pest disease, morbidity is unexpected, infects the control of the feature such as fast, and uneasy to recur,
And it is without any side effects, use safety.
Beneficial effects of the present invention are investigated：
1st, the recipe determination research of traditional Chinese medicine injection of the present invention：
Experimental animal：The big white mouse (120 ± 4g) of Pass Test standard is taken, 200, big white mouse is infected with ewcastle disease virus,
It will appear from lassitude, the blue color of auricle, the successful big white mouse of modeling takes out 140, be randomly divided into 7 groups, every group 20, with such as
Lower test group prescription drug is treated, and test result analysis are carried out after 4 days.
Test group 1：Using radix bupleuri 3g, cordate houttuynia 3g, sealwort 5g, barrenwort 5g, selfheal 3g, schizonepeta 3g, rattletop 3g, green grass or young crops
Traditional Chinese medicine injection is made in wormwood artemisia 3g, perilla leaf 6g, Radix Isatidis 3g；
Test group 2：By radix bupleuri 8g, cordate houttuynia 8g, sealwort 8g, barrenwort 8g, selfheal 8g, schizonepeta 5g, rattletop 5g, sweet wormwood
Traditional Chinese medicine injection is made in 8g, perilla leaf 11g, Radix Isatidis 8g；
Test group 3：Using the traditional Chinese medicine injection for the treatment of checken pest, by weight, by 14 parts of radix bupleuri, 14 parts of cordate houttuynia, Huang
9 parts of essence, 9 parts of barrenwort, 14 parts of selfheal, 6 parts of schizonepeta, 6 parts of rattletop, 14 parts of sweet wormwood, 12 parts of perilla leaf, 14 parts of systems of Radix Isatidis
Into；
Test group 4：Using by radix bupleuri 20g, cordate houttuynia 20g, Huang 10g, barrenwort 10g, selfheal 20g, schizonepeta 7g, rattletop
The traditional Chinese medicine injection that 7g, sweet wormwood 20g, perilla leaf 13g, Radix Isatidis 20g are made.
Test group 5：Using by radix bupleuri 25g, cordate houttuynia 25g, sealwort 13g, barrenwort 13g, selfheal 25g, schizonepeta 9g, liter
The traditional Chinese medicine injection that numb 9g, sweet wormwood 25g, perilla leaf 18g, Radix Isatidis 25g are made；
Test group 6：Using the traditional Chinese medicine injection for the treatment of checken pest, by weight, by 14 parts of radix bupleuri, 14 parts of cordate houttuynia, Huang
9 parts of essence, 14 parts of selfheal, 6 parts of schizonepeta, 6 parts of rattletop, 14 parts of sweet wormwood, 12 parts of perilla leaf, 14 parts of Radix Isatidis are made；
Test group 7：Using the traditional Chinese medicine injection for the treatment of checken pest, by weight, by 14 parts of radix bupleuri, 14 parts of cordate houttuynia, Huang
9 parts of essence, 9 parts of barrenwort, 14 parts of selfheal, 14 parts of sweet wormwood, 12 parts of perilla leaf, 14 parts of Radix Isatidis are made；
Blank control group：Do not give any pharmaceutical intervention.
Equal conditions free water diet during experiment, test group 1-7 injects 5ml/kg to big white mouse daily, is united after 4 days
Count treatment, result of the test such as table 1 below：
| Test group | Number of animals | Cure number | Significant figure | Invalid number | Death toll |
| Test group 1 | 20 | 13 | 4 | 2 | 1 |
| Test group 2 | 20 | 13 | 4 | 2 | 1 |
| Test group 3 | 20 | 14 | 3 | 3 | 0 |
| Test group 4 | 20 | 14 | 4 | 2 | 0 |
| Test group 5 | 20 | 14 | 5 | 1 | 0 |
| Test group 6 | 20 | 8 | 3 | 4 | 5 |
| Test group 7 | 20 | 9 | 2 | 4 | 5 |
| Control group | 20 | 4 | 3 | 3 | 10 |
Result of the test shows, test group 1-7 to treatment big white mouse ewcastle disease virus (CSFV) metainfective therapeutic effect with it is right
Compare according to group, be respectively provided with significant curative effect, and test group 1-5 is significantly better than test group 6-7 groups, therefore, preferred therapeutic of the present invention
The traditional Chinese medicine injection of checken pest is：By 3-25 parts of radix bupleuri, 3-25 parts of cordate houttuynia, 5-13 parts of sealwort, 5-13 parts of barrenwort, selfheal 3-
25 parts, 3-9 parts of schizonepeta, 3-9 parts of rattletop, 3-25 parts of sweet wormwood, 6-18 parts of perilla leaf, 3-25 parts of Radix Isatidis be made；More preferably by bavin
8-20 parts of Hu, 8-20 parts of cordate houttuynia, 8-10 parts of sealwort, 8-10 parts of barrenwort, 8-20 parts of selfheal, 5-7 parts of schizonepeta, rattletop 5-7
Part, 8-20 parts of sweet wormwood, 11-13 parts of perilla leaf, 8-20 parts of Radix Isatidis are made；Most preferably by 14 parts of radix bupleuri, 14 parts of cordate houttuynia, sealwort
9 parts, 9 parts of barrenwort, 14 parts of selfheal, 6 parts of schizonepeta, 6 parts of rattletop, 14 parts of sweet wormwood, 12 parts of perilla leaf, 14 parts of Radix Isatidis be made.
2nd, the traditional Chinese medicine injection clinical tests for the treatment of checken pest produced by the present invention：
In the chicken and duck pestilence that in April, 2016 occurs, two groups are divided into 120 diseased chickens and is treated, every group 60；
Test group：To wanting parenteral solution produced by the present invention to be treated, injection volume is 3ml/1kg, once a day, and successive administration 4 days is right
According to group 2：Using how malicious treatment-resistant, successive administration 4 days carries out result of the test investigation, wherein, test group treats having for checken pest diseased chicken
Efficiency is up to 84%, and control group treats the efficient up to 81% of checken pest disease.Illustrate the obtained Chinese medicine traditional Chinese medicine injection of the present invention to checken pest
Disease has significant curative effect, suitable with how malicious anti-effect.
3rd, traditional Chinese medicine injection Toxicity test of the present invention：
Take testing standard mouse (19 ± 1.2g) 40, be randomly divided into 2 groups, test group give injection it is produced by the present invention in
Medicine parenteral solution parenteral solution, injection volume is 10ml/kg, is administered once daily, successive administration 7 days, control group：Any medicine is not awarded
Intervene, two groups of equal conditions carry out drinking water diet, as a result continuous 15 days observation mouse show, two groups of mouse survival behaviors, activities
It is normal and drinking water diet is without significant difference.Illustrate safety non-toxic of the present invention, to chicken without obvious injury.
Embodiment：
Embodiment 1：Treat the preparation method of the traditional Chinese medicine injection of checken pest
Formula：Using radix bupleuri 3g, cordate houttuynia 3g, sealwort 5g, barrenwort 5g, selfheal 3g, schizonepeta 3g, rattletop 3g, sweet wormwood
3g, perilla leaf 6g, Radix Isatidis 3g；
Preparation method：
(1) radix bupleuri, cordate houttuynia, sealwort, barrenwort, selfheal, schizonepeta, rattletop, sweet wormwood, perilla leaf, the plate of above-mentioned amount are taken
Blue root is crushed, plus the decocting of 6 times of amounts boils secondary, 1.5 hours for the first time, and second 1 hour, collecting decoction, filtration, filtrate was standby
With；
(2) above-mentioned filtrate is concentrated into relative density for 1.00-1.05 under conditions of 50 DEG C, adds ethanol to content
Alcohol amount 70%, stirs, filtration；Ethanol is reclaimed with single-action concentration method, same method is handled 2-4 times；Add 1 times of weight
Then ground water for injection, filtration adds the activated carbon decolorizing of filtrate weight 1%, filtration；Again with ammoniacal liquor regulation pH value to 8.0,
Refrigerated 12 hours at 4 DEG C, then filtration heats deammoniation, make pH value to 5.0, standby；
(3) the treated filtrate of step (2) is taken to be filtered again with 0.45 μm of miillpore filter；Embedding, every 3mL, 110 DEG C go out
Bacterium, obtains parenteral solution.
Embodiment 2：Treat the preparation method of the traditional Chinese medicine injection of checken pest
Formula：Using radix bupleuri 8g, cordate houttuynia 8g, sealwort 8g, barrenwort 8g, selfheal 8g, schizonepeta 5g, rattletop 5g, sweet wormwood
8g, perilla leaf 11g, Radix Isatidis 8g；
Preparation method：
(1) radix bupleuri, cordate houttuynia, sealwort, barrenwort, selfheal, schizonepeta, rattletop, sweet wormwood, perilla leaf, the plate of above-mentioned amount are taken
Blue root is crushed, plus the decocting of 6 times of amounts boils secondary, 1.5 hours for the first time, and second 1 hour, collecting decoction, filtration, filtrate was standby
With；
(2) above-mentioned filtrate is concentrated into relative density for 1.00-1.05 under conditions of 50 DEG C, adds ethanol to content
Alcohol amount 70%, stirs, filtration；Ethanol is reclaimed with single-action concentration method, same method is handled 2-4 times；Add 1 times of weight
Then ground water for injection, filtration adds the activated carbon decolorizing of filtrate weight 1%, filtration；Again with ammoniacal liquor regulation pH value to 8.0,
Refrigerated 12 hours at 4 DEG C, then filtration heats deammoniation, make pH value to 5.0, standby；
(3) the treated filtrate of step (2) is taken to be filtered again with 0.45 μm of miillpore filter；Embedding, every 3mL, 110 DEG C go out
Bacterium, obtains parenteral solution.
Embodiment 3：Treat the preparation method of the traditional Chinese medicine injection of checken pest
Formula：By 14 parts of radix bupleuri, 14 parts of cordate houttuynia, 9 parts of sealwort, 9 parts of barrenwort, 14 parts of selfheal, 6 parts of schizonepeta, rattletop 6
Part, 14 parts of sweet wormwood, 12 parts of perilla leaf, Radix Isatidis 14g；
Preparation method：
(1) radix bupleuri, cordate houttuynia, sealwort, barrenwort, selfheal, schizonepeta, rattletop, sweet wormwood, perilla leaf, the plate of above-mentioned amount are taken
Blue root is crushed, plus the decocting of 7 times of amounts boils secondary, 1.5 hours for the first time, and second 1 hour, collecting decoction, filtration, filtrate was standby
With；
(2) above-mentioned filtrate is concentrated into relative density for 1.00-1.05 under conditions of 50 DEG C, adds ethanol to content
Alcohol amount 70%, stirs, filtration；Ethanol is reclaimed with single-action concentration method, same method is handled 2-4 times；Add 1 times of weight
Then ground water for injection, filtration adds the activated carbon decolorizing of filtrate weight 1%, filtration；Again with ammoniacal liquor regulation pH value to 8.5,
Refrigerated 18 hours at 4-0 DEG C, then filtration heats deammoniation, make pH value to 6.0, standby；
(3) the treated filtrate of step (2) is taken to be filtered again with 0.45 μm of miillpore filter；Embedding, every 3mL, 115 DEG C go out
Bacterium, obtains parenteral solution.
Embodiment 4：Treat the preparation method of the traditional Chinese medicine injection of checken pest
Formula：By radix bupleuri 20g, cordate houttuynia 20g, Huang 10g, barrenwort 10g, selfheal 20g, schizonepeta 7g, rattletop 7g, sweet wormwood
20g, perilla leaf 13g, Radix Isatidis 20g；
Preparation method：
(1) radix bupleuri, cordate houttuynia, sealwort, barrenwort, selfheal, schizonepeta, rattletop, sweet wormwood, perilla leaf, the plate of above-mentioned amount are taken
Blue root is crushed, plus the decocting of 8 times of amounts boils secondary, 1.5 hours for the first time, and second 1 hour, collecting decoction, filtration, filtrate was standby
With；
(2) above-mentioned filtrate is concentrated into relative density for 1.00-1.05 under conditions of 50 DEG C, adds ethanol to content
Alcohol amount 70%, stirs, filtration；Ethanol is reclaimed with single-action concentration method, same method is handled 2-4 times；Add 1 times of weight
Then ground water for injection, filtration adds the activated carbon decolorizing of filtrate weight 1%, filtration；Again with ammoniacal liquor regulation pH value to 9.0,
Refrigerated 12-24 hours at 4-0 DEG C, then filtration heats deammoniation, make pH value to 7.0, standby；
(3) the treated filtrate of step (2) is taken to be filtered again with 0.45 μm of miillpore filter；Embedding, every 3mL, 120 DEG C go out
Bacterium, obtains parenteral solution.
Embodiment 5：Treat the preparation method of the traditional Chinese medicine injection of checken pest
Formula：By radix bupleuri 25g, cordate houttuynia 25g, sealwort 13g, barrenwort 13g, selfheal 25g, schizonepeta 9g, rattletop 9g, green grass or young crops
Wormwood artemisia 25g, perilla leaf 18g, Radix Isatidis 25g；
Preparation method：
(1) radix bupleuri, cordate houttuynia, sealwort, barrenwort, selfheal, schizonepeta, rattletop, sweet wormwood, perilla leaf, the plate of above-mentioned amount are taken
Blue root is crushed, plus the decocting of 8 times of amounts boils secondary, 1.5 hours for the first time, and second 1 hour, collecting decoction, filtration, filtrate was standby
With；
(2) above-mentioned filtrate is concentrated into relative density for 1.00-1.05 under conditions of 50 DEG C, adds ethanol to content
Alcohol amount 70%, stirs, filtration；Ethanol is reclaimed with single-action concentration method, same method is handled 2-4 times；Add 1 times of weight
Then ground water for injection, filtration adds the activated carbon decolorizing of filtrate weight 1%, filtration；Again with ammoniacal liquor regulation pH value to 9.0,
Refrigerated 12-24 hours at 4-0 DEG C, then filtration heats deammoniation, make pH value to 7.0, standby；
(3) the treated filtrate of step (2) is taken to be filtered again with 0.45 μm of miillpore filter；Embedding, every 3mL, 120 DEG C go out
Bacterium, obtains parenteral solution.
Claims (8)
1. a kind of traditional Chinese medicine injection for treating checken pest, it is characterised in that：By weight, by 3-25 parts of radix bupleuri, cordate houttuynia 3-25
Part, 5-13 parts of sealwort, 5-13 parts of barrenwort, 3-25 parts of selfheal, 3-9 parts of schizonepeta, 3-9 parts of rattletop, 3-25 parts of sweet wormwood, perilla leaf
6-18 parts, 3-25 parts of Radix Isatidis is made.
2. the traditional Chinese medicine injection for the treatment of checken pest according to claim 1, it is characterised in that：By weight, by radix bupleuri 8-
20 parts, it is 8-20 parts of cordate houttuynia, 8-10 parts of sealwort, 8-10 parts of barrenwort, 8-20 parts of selfheal, 5-7 parts of schizonepeta, 5-7 parts of rattletop, blue or green
8-20 parts of wormwood artemisia, 11-13 parts of perilla leaf, 8-20 parts of Radix Isatidis are made.
3. the traditional Chinese medicine injection for the treatment of checken pest according to claim 1 or 2, it is characterised in that：By weight, by radix bupleuri
14 parts, 14 parts of cordate houttuynia, 9 parts of sealwort, 9 parts of barrenwort, 14 parts of selfheal, 6 parts of schizonepeta, 6 parts of rattletop, 14 parts of sweet wormwood, perilla leaf
12 parts, 14 parts of Radix Isatidis is made.
4. a kind of preparation method for the traditional Chinese medicine injection for treating checken pest, it is characterised in that：Comprise the following steps：
(1) radix bupleuri, cordate houttuynia, sealwort, barrenwort, selfheal, schizonepeta, rattletop, sweet wormwood, perilla leaf, the Radix Isatidis of above-mentioned amount are taken
Crush, plus the 6-8 times of decocting measured boils secondary, 1.5 hours for the first time, second 1 hour, collecting decoction, filtration, filtrate was standby；
(2) above-mentioned filtrate is concentrated into relative density for 1.00-1.05 under conditions of 50 DEG C, adds ethanol to content alcohol amount
70%, stir, filter；Ethanol is reclaimed with single-action concentration method, same method is handled 2-4 times；Note with adding 1 times of weight
Penetrate and use water, filter, then add the activated carbon decolorizing of filtrate weight 1%, filtration；Again with ammoniacal liquor regulation pH value to 8.0-9.0,
Refrigerated 12-24 hours at 4-0 DEG C, then filtration heats deammoniation, make pH value to 5.0-7.0, standby；
(3) the treated filtrate of step (2) is taken to be filtered again with 0.45 μm of miillpore filter；Embedding, every 3mL, 110-120 DEG C goes out
Bacterium, obtains parenteral solution.
5. the preparation method of the traditional Chinese medicine injection of checken pest is treated according to claim 4, it is characterised in that：The step (1) takes
Radix bupleuri, cordate houttuynia, sealwort, barrenwort, selfheal, schizonepeta, rattletop, sweet wormwood, perilla leaf, the Radix Isatidis for the amount of stating are crushed, plus 7 times of amounts
Decocting boil secondary, 1.5 hours for the first time, second 1 hour, collecting decoction, filtration, filtrate was standby.
6. the preparation method of the traditional Chinese medicine injection of checken pest is treated according to claim 4, it is characterised in that：Described step (2) exists
Above-mentioned filtrate is concentrated into relative density for 1.00-1.05 under conditions of 50 DEG C, ethanol is added to content alcohol amount 70%, stirring
Uniformly, filter；Ethanol is reclaimed with single-action concentration method, same method is handled 3 times；Water for injection, is filtered with adding 1 times of weight
Cross, then add the activated carbon decolorizing of filtrate weight 1%, filtration；PH value is adjusted to 8.5 with ammoniacal liquor again, 18 is refrigerated at 2 DEG C small
When, then filtration heats deammoniation, makes pH value to 6.0, standby.
7. the preparation method of the traditional Chinese medicine injection of checken pest is treated according to claim 4, it is characterised in that：Described step (3) takes
The treated filtrate of step (2) is filtered with 0.45 μm of miillpore filter again；Embedding, every 3mL, 115 DEG C of sterilizings are injected
Liquid.
8. the preparation method of the traditional Chinese medicine injection of checken pest is treated according to claim 4, it is characterised in that：Described traditional Chinese medicine injection
In use, being to use administered intramuscular, by i.e. chicken weight 3ml/kg.
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