CN107137343A - A kind of skin base solution with self-regeneration microecological balance ability and preparation method thereof - Google Patents
A kind of skin base solution with self-regeneration microecological balance ability and preparation method thereof Download PDFInfo
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- CN107137343A CN107137343A CN201710557135.1A CN201710557135A CN107137343A CN 107137343 A CN107137343 A CN 107137343A CN 201710557135 A CN201710557135 A CN 201710557135A CN 107137343 A CN107137343 A CN 107137343A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/99—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/602—Glycosides, e.g. rutin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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Abstract
The present invention discloses a kind of skin base solution with self-regeneration microecological balance ability, by being made including following weight percent composition：Sodium Hyaluronate 0.05 0.1%, carbomer 0.05 0.2%, triethanolamine 0.05 0.2%, disodium ethylene diamine tetraacetate 0.05 0.1%, reed fragrant plant oil 1.5 2.5%, methyl p-hydroxybenzoate 0.05 0.1%, Apple cell culture extract 2 3%, glycosylglycerol 0.5 1%, Ganodernaa lucidum extract 2 3%, palmityl tripeptides 52 5%, α ursin 2 5%, dendrobium candidum extract 0.5 1%, decoyl hydroximic acid 0.5 1% and azone 0.5 2%.The beneficial effects of the invention are as follows：Effective repair cell damage, promotes the metabolism of cell, using getting off, and obscure uneven skin becomes bright water profit, and myoplasm also becomes very soft texture, and skin seems very young.
Description
Technical field
The present invention relates to cosmetic field, specifically a kind of skin base solution with self-regeneration microecological balance ability
And preparation method thereof.
Background technology
Skin base solution imitates cell membrane to develop, and its suitable skin shortage elastic fibers albumen, skin lipid are impaired, skin
Skin relaxation sagging or aging, melanocyte, the thick obscure unglazed, pore of releive sensitive skin, skin, shrivelled skin and angle
The crowd of the matter layer defect such as thin, can permeate skin bottom rapidly, and nutritional ingredient makes elasticity of skin organized renewing soft and moist smooth
Lines, balance sebum secretion, control the acid-base balance of skin.Modern study shows that gene determines the rejuvenation shape of skin root
State, carries the mission of skin self-regeneration.With advancing age, natural climate pollutes, the ecological self-cleaning of skin microbial
Ability is reduced, and " barrier " cell tissue of generation is constantly reduced, and skin itself defensive ability/resistance ability and local skin environment are increasingly damaged.
The market status of existing skin base solution is more chaotic, and effect living features are not distinct, it is impossible to real to improve the micro- life of skin
State is balanced.
The content of the invention
The purpose of the present invention is that the deficiency existed for prior art described above makes skin be repaiied with self there is provided one kind
The skin base solution of multiple microecological balance ability.
It is a further object of the present invention to provide a kind of preparation side of the skin base solution with self-regeneration microecological balance ability
Method.
To achieve the object of the present invention, present invention employs following technical scheme：There is one kind self-regeneration Tiny ecosystem to put down
The skin base solution of weighing apparatus ability, is made up of following weight percent composition：Deionized water 50%-55%, 1,3-PD 25-30%,
Glycerin ether -268%-12%, Sodium Hyaluronate 0.05-0.1%, carbomer 0.05-0.2%, triethanolamine 0.05-0.2%, second
Edetate disodium 0.05-0.1%, reed fragrant plant oil 1.5-2.5%, methyl p-hydroxybenzoate 0.05-0.1%, Apple
Cell culture extract 2-3%, glycosylglycerol 0.5-1%, Ganodernaa lucidum extract 2-3%, palmityl tripeptides -52-5%, α -
Ursin 2-5%, dendrobium candidum (DENDROBIUM CANDIDUM) extract 0.5-1%, decoyl hydroximic acid 0.5-1%, azone
0.5-2%.
Further, the skin base solution with self-regeneration microecological balance ability, by following weight percent composition
It is made：Deionized water 55.6%, 1,3-PD 25%, glycerin ether -26 8%, Sodium Hyaluronate 0.05%, carbomer
0.1%, triethanolamine 0.1%, disodium ethylene diamine tetraacetate 0.05%, reed fragrant plant oil 2%, methyl p-hydroxybenzoate 0.1%, apple
Fruits cell culture extract 1%, glycosylglycerol 0.5%, Ganodernaa lucidum extract 2%, palmityl tripeptides -52%, α-bear
Fruit glycosides 2%, dendrobium candidum extract 0.5%, decoyl hydroximic acid 0.5%, azone 0.5%.
The reed fragrant plant oil is glycerine polymethacrylates, Gantrez AN-119 (polyglycerolmethacrylate/poly- methyl
Vinyl ethers/cis-1 ester copolymer) or polyglycerolmethacrylate/propane diols/polymethyl vinyl ether/suitable
Formula butene dioic acid ester copolymer.
A kind of preparation method of the skin base solution with self-regeneration microecological balance ability, the step of it includes is as follows：
(1) deionized water is first heated to 75~85 DEG C, adds 1,3-PD, glycerin ether -26, Sodium Hyaluronate, second
Edetate disodium, carbomer, methyl p-hydroxybenzoate stirring mixing homogenous disperse are stirred to after transparent, adding triethanolamine
Mix well mixed, vacuumizing and defoaming is incubated 20-30 minutes；
(2) 50 DEG C are cooled to and adds reed fragrant plant oil, 40 DEG C of addition decoyl hydroximic acids are cooled to, Apple cell culture is carried
Thing, glycosylglycerol, Ganodernaa lucidum extract, palmityl tripeptides -5, alpha-arbutin, dendrobium candidum extract and azone are taken, is stirred
Uniform to 38 DEG C stop stirring and get product.
Compared with prior art, the beneficial effects of the invention are as follows：It can improve that skin is dark yellow, problem of rough, build health
Skin cell, the damage of effective repair cell promotes the metabolism of cell, skin is become bright water profit, and myoplasm also becomes
Very soft texture is obtained, skin seems very young；The skin quality of skin is improved, the fine and smooth sense and softening degree for making skin are significantly carried
It is high.
Embodiment
Below by way of specific embodiment come the present invention is further illustrated, but these embodiments simply to illustrate that,
It is not limitation of the present invention.
Gene determines the younger state of skin root, carries the mission of skin self-regeneration.When Time fleets past, gene
Activity reduction, " maintenance " protein amounts of generation are constantly reduced, and the bottom of skin is increasingly damaged.Change skin dark yellow, thick
Rough problem, it is necessary to since the skin cell for building health, because cell neogenesis, skin, which is just understood, penetrating be full of light, skin
Problem can just be improved.2-5% alpha-arbutin is rich in inventive formulation, effective repair cell damage promotes cell
Metabolism, using getting off, obscure uneven skin becomes bright water profit, and myoplasm also becomes very soft texture, and skin has been seen
Come very young.Synthesized by reactivating " maintenance " protein, palmityl tripeptides -5 can improve the skin quality of skin, make skin
Exquisiteness sense and softening degree are significantly improved, and the outward appearance of skin obtains unprecedented change.
Apple (MALUS DOMESTICA) fruit cell culture extract in inventive formulation is one kind with plant
Based on stem cell, can protect and activating skin stem cell and delaying skin aging revolutionary anti-aging actives.Will be auspicious
After scholar's apple is activated in cell culture mode, then largely bred with containers for culturing organisms, turn out rich in tannin, vitality it is extremely strong,
Equivalent to the callus cell of plant stem cell, applied to beauty treatment fields can protecting skin stem cell, delaying skin cell is old
Change, eliminate deep wrinkles, effectively reduce crow's feet.
Glycosylglycerol in inventive formulation is to bring back to life grass (not dead grass) to skim the cream off milk.It is that one kind is grown on pole to bring back to life grass
Under the severe African Extreme drought desert Environment in end, life still there may be, and can continue to deposit in the case where losing 98% water
Decades living, whenever rainy season set, it can come back to life again, miraculously reply several times full of green.Can applied to beauty treatment fields
Strengthen weak cell viability；Accelerating wound healing and tissue repair；Mitigate rubefaction, resist erythema；Increase skin moisture retention,
Elasticity and smoothness；Microgroove and wrinkle are smoothed, help is repaired skin and compacted, keep out ultraviolet, environmental pollution and internal micro-pressure
The injury brought.
Red sesame (GANODERMA LUCIDUM) extract is added in inventive formulation.Red sesame (Antrodia camphorata) also known as cinnamomum kanahirai hay mushroom,
Belong to Aphyllophorales, Polyporaceae, antrodia karst, perennial gill fungus mushroom；The product growth district is Taiwan mountain area height above sea level 450-
Between 2000 meters of mountain forests, be only grown in Taiwan it is peculiar it is century-old more than cinnamomum kanehirai trunk rotten heartwood inwall, or withered lodging
Cinnamomum kanehirai timber moist surface.Antrodia camphorata is the physiologically active ingredient for having many, such as polysaccharide body, triterpene compound, super oxygen discrimination
Change enzyme, adenosine, protein (containing immune protein), vitamin, trace element, nucleic acid, agglutinin, amino acid, solid liquor-saturated tired, fiber
Element, blood pressure stabilization material etc..Using triterpene compound as most especially in the active ingredient of Antrodia camphorata, up to more than 200 kinds, be it
What its mushroom can not be compared, more than 200 kinds of triterpene compounds make Antrodia camphorata have the effects such as anticancer, liver protection.It is applied to anti-hair
Scorching product, aging products, sensitive flesh care product, postoperative care product.Antrodia camphorata extract is for preceding inflammatory factor
(PGE2), with inhibition, therefore Antrodia camphorata extract has effect of releiving for situations such as red caused by inflammation, swollen, hot, pains
Really.
Palmityl tripeptides -5 (Palm-Lys-Val-Lys-OH) are added in inventive formulation.Palmityl tripeptides -5 are three
The two ends of individual amino acid have connected palm ester group respectively, and one end has connected hydrophilic acyl group.So as to enhance the affinity to skin
Ability.Its molecular weight is small, and the skin corium that can go directly plays a role.
Alpha-arbutin is added in inventive formulation.Alpha-arbutin extracts the leaf from black bearberry, and ursin is derived from green plant
The natural active matter of thing, collection " green plants, safe and reliable " and " efficient decolorizing " three close that humorous to be unified in integral skin de-
Colour cell part, it can rapidly permeate into skin, while not influenceing cell to breed concentration, can effectively suppress the tyrosine in skin
The activity of enzyme, blocks the formation of melanin, by itself and junket ammonia enzyme directly in conjunction with, accelerate the decomposition and excretion of melanin, from
And Skin pigmentation is reduced, dispelling stain and freckle, and do not produce toxic, excitant, sensitization to melanocyte
Deng side effect, while also having sterilization, the effect of anti-inflammatory.It is current popular the most safely and effectively whitening raw material, is also two
The desired skin whitening spot-removing activating agent of eleventh century.Many people especially fear to the light sensitivity of ursin, in fact big without load
The heart, experiment shows that only ursin of the concentration more than 7% is possible to meeting to photaesthesia, so 7% is a safety critical point, bear
The characteristics of fruit glycosides is maximum is that bioactive molecule can penetrate the basalis progress light spot of depth, for chloasma, blackspot, sunburn, medicine
The pigmentation that thing allergy is carried over all very strong therapeutic actions, but concentration is too low, the persistence of its effect can weaken, so
2% concentration is most safe and most efficient light spot concentration, and the light spot effect of 2% concentration ratio Vitamin C is fast, and light spot is lasting
Property it is stable, irritation effect will not be produced to skin.Alpha-arbutin can repair skin because of UV-induced damage, call skin back
Transparent feel.By remarkable endurance and penetration, ultraviolet is resisted for a long time in skin surface, and go deep into skin suppression quilt
UV-activated melanin generation.Alpha-arbutin is the crystallization of sophisticated technologies.It is difficult by the beta-glucosidase of skin surface
Decompose, effect is about 10 times of conventional β-ursin.Can rest on the every nook and cranny of skin for a long time, sustainable protection skin not by
Injury.Melanin is to form the reason for skin is obscure, and alpha-arbutin can infiltrate into skin depths rapidly, and suppression is present in cuticula
The activity of tyrosinase in the chromoplast of depths, and in skin surface formation double effectses, suppress the generation of melanin.
All components are shared above, can Synergistic.Promote the metabolism of cell, obscure uneven skin can be made after use
Become bright water profit, myoplasm also becomes very soft texture, and skin seems very young.
Embodiment 1
A kind of skin base solution with self-regeneration microecological balance ability, is made up of following weight percent composition：Go from
Sub- water 50%, 1,3-PD 29.3%, glycerin ether -268%, Sodium Hyaluronate 0.1%, carbomer 0.2%, triethanolamine
0.2%, disodium ethylene diamine tetraacetate 0.1%, reed fragrant plant oil 2%, methyl p-hydroxybenzoate 0.1%, Apple cell culture
Thing extract 2%, glycosylglycerol 0.5%, Ganodernaa lucidum extract 2%, palmityl tripeptides -52%, alpha-arbutin 2%, iron sheet stone
Dry measure used in former times extract 0.5%, decoyl hydroximic acid 0.5%, azone 0.5%.
Embodiment 2
A kind of skin base solution with self-regeneration microecological balance ability, is made up of following weight percent composition：Go from
Sub- water 50%, 1,3-PD 25%, glycerin ether -2610%, Sodium Hyaluronate 0.05%, carbomer 0.05%, triethanolamine
0.05%, disodium ethylene diamine tetraacetate 0.05%, reed fragrant plant oil 1.5%, methyl p-hydroxybenzoate 0.05%, Apple cell
Culture extract 2%, glycosylglycerol 1%, Ganodernaa lucidum extract 2%, palmityl tripeptides -52.5%, alpha-arbutin 3%, iron
Skin Herba Dendrobii extract 0.75%, decoyl hydroximic acid 1%, azone 1%.
Embodiment 3
A kind of skin base solution with self-regeneration microecological balance ability, is made up of following weight percent composition：Go from
Sub- water 55.6%, 1,3-PD 25%, glycerin ether -26 8%, Sodium Hyaluronate 0.05%, carbomer 0.1%, triethanolamine
0.1%, disodium ethylene diamine tetraacetate 0.05%, reed fragrant plant oil 2%, methyl p-hydroxybenzoate 0.1%, Apple cell culture
Thing extract 1%, glycosylglycerol 0.5%, Ganodernaa lucidum extract 2%, palmityl tripeptides -52%, alpha-arbutin 2%, iron sheet stone
Dry measure used in former times extract 0.5%, decoyl hydroximic acid 0.5%, azone 0.5%.
The preparation method of the above-mentioned skin base solution with self-regeneration microecological balance ability, the step of it includes is as follows：
(1) deionized water is first heated to 80 DEG C, adds 1,3-PD, glycerin ether -26, Sodium Hyaluronate, ethylenediamine
Tetraacethyl disodium, carbomer, methyl p-hydroxybenzoate stirring mixing homogenous disperse are mixed to triethanolamine stirring after transparent, is added
Close uniform, vacuumizing and defoaming is incubated 25 minutes；
(2) 50 DEG C are cooled to and adds reed fragrant plant oil, 40 DEG C of addition decoyl hydroximic acids are cooled to, Apple cell culture is carried
Thing, glycosylglycerol, Ganodernaa lucidum extract, palmityl tripeptides -5, alpha-arbutin, dendrobium candidum extract and azone are taken, is stirred
Uniform to 38 DEG C stop stirring and get product.
Raw material used in the present invention is included《Cosmetic material Names Catalogue is used》In (2015 editions), purchase can be passed through
Buy acquisition, and safety.
Effect experiment
First, experimental method and whitening function evaluation
1st, the preparation of sample
Respectively by the sample of embodiment 1, embodiment 2 and embodiment 3, test below.
2nd, tyrosinase activity rejection ability is evaluated
Sample is placed in constant temperature 10min in 37 DEG C of water-baths；Tyrosinase is added, solution is placed in constant temperature in 37 DEG C of water-baths
After 10min, solution is prepared, in measuring its absorbance under 475nm, is compared.
Table 1
Sample is calculated to the relative inhibition of tyrosinase (I, abbreviation inhibiting rate, similarly hereinafter) by formula (1).
In formula：A1, A2, A3, A4 are respectively the absorbance of 1 group~4 groups solution.
3rd, experimental result
Table 2 is to tyrosinase inhibition rate result
Experiment shows, the present invention is up to more than 70% to inhibitory activity against tyrosinase, and the common product of market sale
To inhibitory activity against tyrosinase typically below 50%, illustrate that the synergy between each component of the present invention is notable, to tyrosine
The inhibiting rate of enzyme is high, with good whitening effect.
2nd, normal individual trial evaluation experimental
1st, experimental method
Embodiment 1, embodiment 2 and embodiment 3 and blank example sample carry out normal individual trial evaluation.Choose healthy volunteer
60, the age, men and women half and half at 25 to 50 years old.It is randomly divided into 2 groups, every group of 15 males, 15 women.Each group is applied respectively
Check experiment is smeared, left side uses blank sample, and right side uses embodiment 1, embodiment 2 and the sample of embodiment 3, daily night to make before sleeping
With once, persistently try out 30 days, use the colour of skin that left face and right face are observed after one month.
Moisturizing degree, glossiness and whitening degree are carried out during use to sample to evaluate, wherein highest is divided into 5, minimum to be divided into
1。
2nd, experimental result
Evaluation table on probation is filled according to sensory evaluation.Half face experiment evaluation table on probation is collected, statistical result is shown in Table 3：
The normal individual trial evaluation result average value of table 3
From the result of table 3, the result of the face test evaluation of human body half clearly can contrast this example sample and blank sample
Effect difference of product.Embodiment 1, embodiment 2 and embodiment 3 are obvious with the improvement aspect effect of rear glossiness and whitening degree, table
It is bright that there is good whitening nourishing containing the present invention, it can allow coarse dark and gloomy skin speedy recovery to health state, smooth exquisiteness,
It is pale moving.
Preferred embodiment of the invention described in detail above, be inventor take a large amount of manpower financial capacities and when
Between, test of many times come out it will be appreciated that, as a result, the ordinary skill of this area just can be according to this hair without creative work
Many modifications and variations are made in bright design.Therefore, all technical staff in the art according to present inventive concept in prior art
On the basis of by logic analysis, reasoning or according to the limited available technical scheme of experiment, should be by this right
Among protection domain determined by claim.
Claims (3)
1. a kind of skin base solution with self-regeneration microecological balance ability, it is characterised in that：By following weight percent composition
It is made：Deionized water 50%-55%, 1,3-PD 25-30%, glycerin ether -268%-12%, Sodium Hyaluronate 0.05-
0.1%th, carbomer 0.05-0.2%, triethanolamine 0.05-0.2%, disodium ethylene diamine tetraacetate 0.05-0.1%, reed fragrant plant oil
1.5-2.5%, methyl p-hydroxybenzoate 0.05-0.1%, Apple cell culture extract 2-3%, glycosylglycerol
0.5-1%, Ganodernaa lucidum extract 2-3%, palmityl tripeptides -52-5%, alpha-arbutin 2-5%, dendrobium candidum extract 0.5-
1%, decoyl hydroximic acid 0.5-1%, azone 0.5-2%.
2. a kind of skin base solution with self-regeneration microecological balance ability according to claim 1, it is characterised in that：By
Following weight percent composition is made：Deionized water 55.6%, 1,3-PD 25%, glycerin ether -26 8%, Sodium Hyaluronate
0.05%th, carbomer 0.1%, triethanolamine 0.1%, disodium ethylene diamine tetraacetate 0.05%, reed fragrant plant oil 2%, para hydroxybenzene first
Sour methyl esters 0.1%, Apple cell culture extract 1%, glycosylglycerol 0.5%, Ganodernaa lucidum extract 2%, palmityl
Tripeptides -52%, alpha-arbutin 2%, dendrobium candidum extract 0.5%, decoyl hydroximic acid 0.5%, azone 0.5%.
3. a kind of preparation method of the skin base solution with self-regeneration microecological balance ability according to claim 1, it is special
Levy and be, including the step of it is as follows：
(1) deionized water is first heated to 75~85 DEG C, adds 1,3-PD, glycerin ether -26, Sodium Hyaluronate, ethylenediamine
Tetraacethyl disodium, carbomer, methyl p-hydroxybenzoate stirring mixing homogenous disperse are mixed to triethanolamine stirring after transparent, is added
Close uniform, vacuumizing and defoaming is incubated 20-30 minutes；
(2) 50 DEG C are cooled to and adds reed fragrant plant oil, 40 DEG C is cooled to and adds decoyl hydroximic acid, the extraction of Apple cell culture
Thing, glycosylglycerol, Ganodernaa lucidum extract, palmityl tripeptides -5, alpha-arbutin, dendrobium candidum extract and azone, stirring are equal
Even to 38 DEG C stop stirring and get product.
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| CN108158968A (en) * | 2018-01-17 | 2018-06-15 | 浙江理工大学 | A kind of tender skin shines face multiple-effect washing cream and preparation method thereof |
| CN109260116A (en) * | 2018-11-22 | 2019-01-25 | 武汉跃莱健康产业有限公司 | It is a kind of containing plant extracts to peptide skin base solution and its production technology |
| CN110169934A (en) * | 2019-05-27 | 2019-08-27 | 胡清香 | A kind of dual liposomes cosmetics |
| CN110403883A (en) * | 2019-09-03 | 2019-11-05 | 杭州千岛湖蓝色天使实业有限公司 | A kind of long anti-ageing smoothing toner of pubescence Chinese yam and preparation method thereof |
| CN110448506A (en) * | 2019-09-03 | 2019-11-15 | 杭州千岛湖蓝色天使实业有限公司 | A kind of long anti-ageing essence cream of pubescence Chinese yam and preparation method thereof |
| CN110787300A (en) * | 2019-12-12 | 2020-02-14 | 中山万远新药研发有限公司 | Composition containing sodium hyaluronate and preparation and application thereof |
| CN111840098A (en) * | 2019-04-16 | 2020-10-30 | 广州爱妃丽尔化妆品科技有限公司 | Novel anti-oxidation essence containing fullerene and preparation process thereof |
| CN112618422A (en) * | 2020-12-24 | 2021-04-09 | 董欣生物科技(广州)有限公司 | Composite whitening composition, preparation method and application |
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Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108158968A (en) * | 2018-01-17 | 2018-06-15 | 浙江理工大学 | A kind of tender skin shines face multiple-effect washing cream and preparation method thereof |
| CN109260116A (en) * | 2018-11-22 | 2019-01-25 | 武汉跃莱健康产业有限公司 | It is a kind of containing plant extracts to peptide skin base solution and its production technology |
| CN111840098A (en) * | 2019-04-16 | 2020-10-30 | 广州爱妃丽尔化妆品科技有限公司 | Novel anti-oxidation essence containing fullerene and preparation process thereof |
| CN110169934A (en) * | 2019-05-27 | 2019-08-27 | 胡清香 | A kind of dual liposomes cosmetics |
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Application publication date: 20170908 |