CN107109488A - 预测对乳腺癌治疗剂的反应的方法和治疗乳腺癌的方法 - Google Patents
预测对乳腺癌治疗剂的反应的方法和治疗乳腺癌的方法 Download PDFInfo
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- CN107109488A CN107109488A CN201580068041.7A CN201580068041A CN107109488A CN 107109488 A CN107109488 A CN 107109488A CN 201580068041 A CN201580068041 A CN 201580068041A CN 107109488 A CN107109488 A CN 107109488A
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4166—1,3-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. phenytoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/14—Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/112—Disease subtyping, staging or classification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Analytical Chemistry (AREA)
- Genetics & Genomics (AREA)
- Pathology (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hospice & Palliative Care (AREA)
- Biotechnology (AREA)
- Oncology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Endocrinology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462091195P | 2014-12-12 | 2014-12-12 | |
| US62/091,195 | 2014-12-12 | ||
| US201562142504P | 2015-04-03 | 2015-04-03 | |
| US62/142,504 | 2015-04-03 | ||
| US201562167110P | 2015-05-27 | 2015-05-27 | |
| US62/167,110 | 2015-05-27 | ||
| PCT/US2015/064500 WO2016094408A1 (en) | 2014-12-12 | 2015-12-08 | Method for predicting response to breast cancer therapeutic agents and method of treatment of breast cancer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107109488A true CN107109488A (zh) | 2017-08-29 |
Family
ID=55273509
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201580068041.7A Pending CN107109488A (zh) | 2014-12-12 | 2015-12-08 | 预测对乳腺癌治疗剂的反应的方法和治疗乳腺癌的方法 |
Country Status (15)
| Country | Link |
|---|---|
| US (3) | US10196693B2 (https=) |
| EP (2) | EP3604556A1 (https=) |
| JP (1) | JP6735277B2 (https=) |
| KR (1) | KR20170095306A (https=) |
| CN (1) | CN107109488A (https=) |
| AU (1) | AU2015360767A1 (https=) |
| BR (1) | BR112017012142A2 (https=) |
| CA (1) | CA2970469A1 (https=) |
| ES (1) | ES2748005T3 (https=) |
| IL (1) | IL252587A0 (https=) |
| MX (1) | MX2017007707A (https=) |
| RU (1) | RU2017120330A (https=) |
| SG (1) | SG11201704425TA (https=) |
| WO (1) | WO2016094408A1 (https=) |
| ZA (1) | ZA201703904B (https=) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109735625A (zh) * | 2019-03-18 | 2019-05-10 | 马榕 | 乳头溢液在检测肿瘤相关基因中的应用 |
| WO2020001473A1 (zh) * | 2018-06-28 | 2020-01-02 | 复旦大学 | 小核仁核糖核酸snord33作为生物标记物用于制备检测试剂盒中的用途 |
| CN114334000A (zh) * | 2021-12-28 | 2022-04-12 | 上海中医药大学 | 基于转录组图谱的组合药物生成方法、系统及存储介质 |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101923250B1 (ko) | 2011-07-29 | 2018-11-28 | 메디베이션 프로스테이트 테라퓨틱스 엘엘씨 | 유방암의 치료 |
| US20140243211A1 (en) | 2013-02-28 | 2014-08-28 | Indiana University Research & Technology Corporation | Blood biomarkers for suicidality |
| SG11201704425TA (en) | 2014-12-12 | 2017-06-29 | Medivation Prostate Therapeutics Inc | Method for predicting response to breast cancer therapeutic agents and method of treatment of breast cancer |
| WO2016201299A1 (en) | 2015-06-12 | 2016-12-15 | Indiana University Research & Technology Corporation | Predicting suicidality using a combined genomic and clinical risk assessment |
| KR101966493B1 (ko) * | 2016-06-27 | 2019-04-05 | 국립암센터 | 삼중음성유방암 예후 예측용 바이오마커 |
| KR101896558B1 (ko) * | 2016-11-21 | 2018-09-07 | 주식회사 젠큐릭스 | 유방암 환자의 예후 예측 방법 |
| JPWO2018198927A1 (ja) * | 2017-04-26 | 2019-11-07 | 日本電信電話株式会社 | N×n光スイッチ |
| CA3105451A1 (en) | 2017-05-12 | 2018-11-15 | Indiana University Research And Technology Corporation | Precision medicine for treating and preventing suicidality |
| RU2648523C1 (ru) * | 2017-05-22 | 2018-03-26 | Федеральное государственное бюджетное научное учреждение "Томский национальный исследовательский медицинский центр" Российской академии наук ("Томский НИМЦ") | Способ прогнозирования исхода заболевания у больных люминальным в и трижды негативным раком молочной железы у пациенток, не получавших в неоадъювантном режиме химио- или гормонотерапию |
| CA3105389C (en) * | 2018-05-14 | 2025-05-20 | Hinova Pharmaceuticals Inc. | A formulation of hc-1119 as well as the production method and the use thereof |
| US20260043086A1 (en) * | 2022-08-06 | 2026-02-12 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Predictive biomarker in avastin in colon cancer |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101917982A (zh) * | 2007-11-12 | 2010-12-15 | 彼帕科学公司 | 单独使用parp抑制剂或与其他抗肿瘤剂组合治疗乳腺癌 |
| CN103997894A (zh) * | 2011-07-29 | 2014-08-20 | 麦迪韦逊前列腺治疗股份有限公司 | 乳癌的治疗 |
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| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US5800992A (en) | 1989-06-07 | 1998-09-01 | Fodor; Stephen P.A. | Method of detecting nucleic acids |
| US6040138A (en) | 1995-09-15 | 2000-03-21 | Affymetrix, Inc. | Expression monitoring by hybridization to high density oligonucleotide arrays |
| EP0880598A4 (en) | 1996-01-23 | 2005-02-23 | Affymetrix Inc | RAPID EVALUATION OF NUCLEIC ACID ABUNDANCE DIFFERENCE, WITH A HIGH-DENSITY OLIGONUCLEOTIDE SYSTEM |
| EP1027456B1 (en) | 1997-10-31 | 2005-03-16 | Affymetrix, Inc. (a Delaware Corporation) | Expression profiles in adult and fetal organs |
| US6020135A (en) | 1998-03-27 | 2000-02-01 | Affymetrix, Inc. | P53-regulated genes |
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| US7504222B2 (en) | 2001-10-31 | 2009-03-17 | Millennium Pharmaceuticals, Inc. | Compositions, kits, and methods for identification, assessment, prevention, and therapy of breast cancer |
| US20070192880A1 (en) | 2003-10-03 | 2007-08-16 | University Of Rochester | Horming response element binding transregulators |
| US20070059720A9 (en) | 2004-12-06 | 2007-03-15 | Suzanne Fuqua | RNA expression profile predicting response to tamoxifen in breast cancer patients |
| US7709517B2 (en) | 2005-05-13 | 2010-05-04 | The Regents Of The University Of California | Diarylhydantoin compounds |
| JP4644737B2 (ja) | 2005-05-13 | 2011-03-02 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | ジアリールヒダントイン化合物 |
| CA2630974A1 (en) | 2005-11-23 | 2007-05-31 | University Of Utah Research Foundation | Methods and compositions involving intrinsic genes |
| LT2656842T (lt) | 2006-03-27 | 2016-09-26 | The Regents Of The University Of California | Androgeno receptoriaus moduliatorius, skirtas prostatos vėžio ir su androgeno receptoriumi susijusių ligų gydymui |
| KR101456722B1 (ko) | 2006-03-29 | 2014-10-31 | 더 리전트 오브 더 유니버시티 오브 캘리포니아 | 디아릴티오히단토인 화합물 |
| TWI469971B (zh) | 2007-10-26 | 2015-01-21 | Univ California | 二芳基乙內醯脲類化合物 |
| US8450290B2 (en) | 2007-11-26 | 2013-05-28 | Enzon Pharmaceuticals, Inc. | Methods for treating androgen receptor dependent disorders including cancers |
| WO2009114534A1 (en) | 2008-03-14 | 2009-09-17 | The Regents Of The University Of California | Multi-gene classifiers and prognostic indicators for cancers |
| DK2297359T3 (en) | 2008-05-30 | 2014-02-24 | Univ Utah Res Found | Gene expression profiles to predict the outcome of breast cancer |
| NZ594741A (en) | 2009-02-24 | 2014-03-28 | Medivation Prostate Therapeutics Inc | Specific diarylhydantoin and diarylthiohydantoin compounds |
| EP2416657A4 (en) | 2009-04-09 | 2012-09-05 | Medivation Prostate Therapeutics Inc | COMPOUNDS COMPRISING SUBSTITUTED DI-ARYLHYDANTOIDS AND DI-ARYLTHIOHYDANTOINES AND METHODS OF USE THEREOF |
| EP2425015B1 (en) | 2009-04-29 | 2018-01-10 | Ralph Wirtz | A method to assess prognosis and to predict therapeutic success in cancer by determining hormone receptor expression levels |
| WO2011022316A1 (en) | 2009-08-20 | 2011-02-24 | The Regents Of The University Of Colorado, A Body Corporate | Mirnas dysregulated in triple-negative breast cancer |
| JP2013504064A (ja) | 2009-09-03 | 2013-02-04 | ザ スクリプス リサーチ インスティチュート | 循環腫瘍細胞を分類する方法 |
| WO2011044327A1 (en) | 2009-10-07 | 2011-04-14 | Medivation Prostate Therapeutics, Inc. | Substituted phenylcarbamoyl alkylamino arene compounds and n,n'-bis-arylurea compounds |
| US8781912B2 (en) | 2011-03-15 | 2014-07-15 | Opera Solutions, Llc | Computer-based method and computer program product for setting floor prices for items sold at auction |
| AU2012229123B2 (en) * | 2011-03-15 | 2017-02-02 | British Columbia Cancer Agency Branch | Methods of treating breast cancer with anthracycline therapy |
| AU2012345789B2 (en) | 2011-11-30 | 2018-02-15 | British Columbia Cancer Agency Branch | Methods of treating breast cancer with taxane therapy |
| US10175240B2 (en) | 2012-08-23 | 2019-01-08 | The Regents Of The University Of Colorado, A Body Corporate | Method for determining breast cancer treatment |
| US9175291B2 (en) * | 2012-10-11 | 2015-11-03 | Isis Pharmaceuticals Inc. | Modulation of androgen receptor expression |
| US20140154681A1 (en) | 2012-11-12 | 2014-06-05 | Nanostring Technologies, Inc. | Methods to Predict Breast Cancer Outcome |
| US10679730B2 (en) * | 2013-05-28 | 2020-06-09 | The University Of Chicago | Prognostic and predictive breast cancer signature |
| SG11201704425TA (en) | 2014-12-12 | 2017-06-29 | Medivation Prostate Therapeutics Inc | Method for predicting response to breast cancer therapeutic agents and method of treatment of breast cancer |
-
2015
- 2015-12-08 SG SG11201704425TA patent/SG11201704425TA/en unknown
- 2015-12-08 US US14/962,864 patent/US10196693B2/en active Active
- 2015-12-08 RU RU2017120330A patent/RU2017120330A/ru not_active Application Discontinuation
- 2015-12-08 BR BR112017012142A patent/BR112017012142A2/pt not_active IP Right Cessation
- 2015-12-08 EP EP19192143.6A patent/EP3604556A1/en not_active Withdrawn
- 2015-12-08 MX MX2017007707A patent/MX2017007707A/es unknown
- 2015-12-08 KR KR1020177019159A patent/KR20170095306A/ko not_active Withdrawn
- 2015-12-08 AU AU2015360767A patent/AU2015360767A1/en not_active Abandoned
- 2015-12-08 JP JP2017531209A patent/JP6735277B2/ja not_active Expired - Fee Related
- 2015-12-08 ES ES15831013T patent/ES2748005T3/es active Active
- 2015-12-08 WO PCT/US2015/064500 patent/WO2016094408A1/en not_active Ceased
- 2015-12-08 CN CN201580068041.7A patent/CN107109488A/zh active Pending
- 2015-12-08 CA CA2970469A patent/CA2970469A1/en active Pending
- 2015-12-08 EP EP15831013.6A patent/EP3230471B1/en not_active Not-in-force
-
2017
- 2017-05-30 IL IL252587A patent/IL252587A0/en unknown
- 2017-06-07 ZA ZA2017/03904A patent/ZA201703904B/en unknown
-
2018
- 2018-12-10 US US16/215,340 patent/US11186876B2/en active Active
-
2021
- 2021-11-10 US US17/523,235 patent/US11952634B2/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101917982A (zh) * | 2007-11-12 | 2010-12-15 | 彼帕科学公司 | 单独使用parp抑制剂或与其他抗肿瘤剂组合治疗乳腺癌 |
| CN103997894A (zh) * | 2011-07-29 | 2014-08-20 | 麦迪韦逊前列腺治疗股份有限公司 | 乳癌的治疗 |
Non-Patent Citations (2)
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| FUTOSHI AKIYAMA等: "Triple Negative Breast Cancer: Clinicopathological Characteristics and Treatment Strategies", 《BREAST CANCER》 * |
| 林能明等: "《新编抗肿瘤药物学》", 31 May 2014, 军事医学科学出版社 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2020001473A1 (zh) * | 2018-06-28 | 2020-01-02 | 复旦大学 | 小核仁核糖核酸snord33作为生物标记物用于制备检测试剂盒中的用途 |
| CN109735625A (zh) * | 2019-03-18 | 2019-05-10 | 马榕 | 乳头溢液在检测肿瘤相关基因中的应用 |
| CN114334000A (zh) * | 2021-12-28 | 2022-04-12 | 上海中医药大学 | 基于转录组图谱的组合药物生成方法、系统及存储介质 |
Also Published As
| Publication number | Publication date |
|---|---|
| US11952634B2 (en) | 2024-04-09 |
| MX2017007707A (es) | 2018-03-06 |
| US20220056541A1 (en) | 2022-02-24 |
| EP3230471A1 (en) | 2017-10-18 |
| JP2018504892A (ja) | 2018-02-22 |
| WO2016094408A1 (en) | 2016-06-16 |
| US20160168646A1 (en) | 2016-06-16 |
| CA2970469A1 (en) | 2016-06-16 |
| JP6735277B2 (ja) | 2020-08-05 |
| US20190169697A1 (en) | 2019-06-06 |
| IL252587A0 (en) | 2017-07-31 |
| SG11201704425TA (en) | 2017-06-29 |
| KR20170095306A (ko) | 2017-08-22 |
| ES2748005T3 (es) | 2020-03-12 |
| US11186876B2 (en) | 2021-11-30 |
| ZA201703904B (en) | 2019-12-18 |
| EP3604556A1 (en) | 2020-02-05 |
| BR112017012142A2 (pt) | 2018-01-02 |
| AU2015360767A1 (en) | 2017-06-08 |
| RU2017120330A3 (https=) | 2019-07-24 |
| EP3230471B1 (en) | 2019-08-28 |
| US10196693B2 (en) | 2019-02-05 |
| RU2017120330A (ru) | 2019-01-14 |
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