CN107074967B - 白介素-2/白介素-2受体α融合蛋白和使用方法 - Google Patents

白介素-2/白介素-2受体α融合蛋白和使用方法 Download PDF

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CN107074967B
CN107074967B CN201580042330.XA CN201580042330A CN107074967B CN 107074967 B CN107074967 B CN 107074967B CN 201580042330 A CN201580042330 A CN 201580042330A CN 107074967 B CN107074967 B CN 107074967B
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fusion protein
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amino acid
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CN107074967A (zh
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T.马列克
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University of Miami
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    • C—CHEMISTRY; METALLURGY
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/55—IL-2
    • A—HUMAN NECESSITIES
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    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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    • A61P37/00—Drugs for immunological or allergic disorders
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
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    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
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    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
    • C07K2319/21—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag

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CN201580042330.XA 2014-08-06 2015-08-05 白介素-2/白介素-2受体α融合蛋白和使用方法 Active CN107074967B (zh)

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US201462033726P 2014-08-06 2014-08-06
US62/033726 2014-08-06
PCT/US2015/043792 WO2016022671A1 (en) 2014-08-06 2015-08-05 Interleukin-2/interleukin-2 receptor alpha fusion proteins and methods of use

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MX2017001062A (es) 2017-07-14
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US20170233448A1 (en) 2017-08-17
AU2015301071C1 (en) 2020-07-02
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US20250163118A1 (en) 2025-05-22
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