CN107074911B - 肽核酸单体和低聚体 - Google Patents

肽核酸单体和低聚体 Download PDF

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CN107074911B
CN107074911B CN201580038548.8A CN201580038548A CN107074911B CN 107074911 B CN107074911 B CN 107074911B CN 201580038548 A CN201580038548 A CN 201580038548A CN 107074911 B CN107074911 B CN 107074911B
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flupac
guanine
atom
lys
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CN107074911A (zh
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T·林霍斯特
B·维尔纳
H·博克
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Ugisense AG
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CN201580038548.8A 2014-05-16 2015-05-15 肽核酸单体和低聚体 Active CN107074911B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102014007158.8 2014-05-16
DE102014007158.8A DE102014007158A1 (de) 2014-05-16 2014-05-16 Neue Peptid-Nukleinsäuren-Monomere und -Oligomere
PCT/EP2015/000998 WO2015172889A1 (de) 2014-05-16 2015-05-15 Peptid-nukleinsäuren-monomere und -oligomere

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CN107074911A CN107074911A (zh) 2017-08-18
CN107074911B true CN107074911B (zh) 2020-11-03

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US (1) US20170166900A1 (enExample)
EP (1) EP3143038B8 (enExample)
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CA3043864A1 (en) * 2016-11-16 2018-05-24 Biomarin Technologies B.V. Substances for targeting various selected organs or tissues
US20180282375A1 (en) * 2017-03-23 2018-10-04 Trucode Gene Repair, Inc. Peptide nucleic acid (pna) monomers with an orthogonally protected ester moiety
GB202109880D0 (en) * 2018-12-13 2021-08-25 Neubase Therapeutics Inc PNA Oligomers and related methods
CA3126947A1 (en) 2019-01-22 2020-07-30 Korro Bio, Inc. Rna-editing oligonucleotides and uses thereof
CA3127243A1 (en) 2019-01-22 2020-07-30 Korro Bio, Inc. Rna-editing oligonucleotides and uses thereof
WO2020154343A1 (en) 2019-01-22 2020-07-30 Korro Bio, Inc. Rna-editing oligonucleotides and uses thereof
KR102403904B1 (ko) * 2019-12-24 2022-06-02 주식회사 시선바이오머티리얼스 용액공정상 pna 올리고머의 제조방법

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US5719262A (en) * 1993-11-22 1998-02-17 Buchardt, Deceased; Ole Peptide nucleic acids having amino acid side chains
CN101495505A (zh) * 2006-07-21 2009-07-29 Ugi化学有限责任公司 被膦酸酯或膦酸取代的手性化合物
CN101547934A (zh) * 2006-10-24 2009-09-30 Ugichem有机化学学会有限公司 在线粒体上和线粒体中选择性定位活性剂的方法以及相应的活性剂

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UA48150C2 (uk) * 1994-11-02 2002-08-15 Ай-Сі-Ен Фармасьютикалз Похідні амінокислот або аміноспиртів, олігонуклеотид
EP0960121B1 (en) * 1996-07-24 2005-11-30 BUCHARDT, Dorte Peptide nucleic acids having enhanced binding affinity, sequence specificity and solubility
IL133087A0 (en) * 1997-05-28 2001-03-19 Nielsen Peter E Conjugated peptide nucleic acids having enhanced cellular uptake
DE19909373A1 (de) * 1999-03-03 2000-10-05 Ugichem Neue PNA-Monomere, daraus resultierende PNA-Oligomere und deren Verwendung
US8575305B2 (en) * 2008-06-04 2013-11-05 Medical Research Council Cell penetrating peptides

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5719262A (en) * 1993-11-22 1998-02-17 Buchardt, Deceased; Ole Peptide nucleic acids having amino acid side chains
CN101495505A (zh) * 2006-07-21 2009-07-29 Ugi化学有限责任公司 被膦酸酯或膦酸取代的手性化合物
CN101547934A (zh) * 2006-10-24 2009-09-30 Ugichem有机化学学会有限公司 在线粒体上和线粒体中选择性定位活性剂的方法以及相应的活性剂

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
"肽核酸的合成、修饰和应用";褚征等;《有机化学》;20051231;第25卷(第3期);第254-263页 *

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US20170166900A1 (en) 2017-06-15
AU2015258476A1 (en) 2016-12-01
CN107074911A (zh) 2017-08-18
KR20170002649A (ko) 2017-01-06
KR102515760B1 (ko) 2023-03-29
CA2949185A1 (en) 2015-11-19
RU2016149427A (ru) 2018-06-20
DK3143038T3 (en) 2018-11-26
ES2683186T3 (es) 2018-09-25
RU2016149427A3 (enExample) 2018-12-05
DE102014007158A1 (de) 2015-11-19
CA2949185C (en) 2023-03-14
RU2693827C2 (ru) 2019-07-05
EP3143038A1 (de) 2017-03-22
JP2017518363A (ja) 2017-07-06
EP3143038B1 (de) 2018-08-01
EP3143038B8 (de) 2018-09-12
AU2015258476B2 (en) 2018-12-20
JP6546272B2 (ja) 2019-07-17
PL3143038T3 (pl) 2019-01-31
WO2015172889A1 (de) 2015-11-19

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