CN107074853B - 咪唑并[4，5-c]吡啶衍生的SSAO抑制剂 - Google Patents
咪唑并[4，5-c]吡啶衍生的SSAO抑制剂 Download PDFInfo
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- CN107074853B CN107074853B CN201580056356.XA CN201580056356A CN107074853B CN 107074853 B CN107074853 B CN 107074853B CN 201580056356 A CN201580056356 A CN 201580056356A CN 107074853 B CN107074853 B CN 107074853B
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| PCT/GB2015/052691 WO2016042332A1 (en) | 2014-09-17 | 2015-09-17 | Imidazo[4,5-c]pyridine derived ssao inhibitors |
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| CN107074853A CN107074853A (zh) | 2017-08-18 |
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| GB201304526D0 (en) * | 2013-03-13 | 2013-04-24 | Proximagen Ltd | New compounds |
| GB201416446D0 (en) * | 2014-09-17 | 2014-10-29 | Proximagen Ltd | New enzyme inhibitor compounds |
| WO2018027892A1 (en) | 2016-08-12 | 2018-02-15 | Eli Lilly And Company | Amino pyrimidine ssao inhibitors |
| WO2018148856A1 (en) * | 2017-02-14 | 2018-08-23 | Eli Lilly And Company | Diazaspirodecanyl-pyrimidine compounds useful as ssao inhibitors |
| AU2021332217A1 (en) | 2020-08-25 | 2023-05-11 | Eli Lilly And Company | Polymorphs of an ssao inhibitor |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002038153A1 (en) * | 2000-11-09 | 2002-05-16 | Biovitrum Ab | New use of 4, 5, 6, 7-tetrahydroimidazo-[4,5-c]pyridine derivatives |
| WO2010031791A1 (en) * | 2008-09-16 | 2010-03-25 | Biovitrum Ab (Publ) | New compounds ii |
| CN102232073A (zh) * | 2008-09-16 | 2011-11-02 | 普罗克西梅根有限公司 | 新化合物i |
| CN103180319A (zh) * | 2010-03-15 | 2013-06-26 | 普罗克斯马根有限公司 | 氨基脲敏感性胺氧化酶抑制剂 |
| CN103797012A (zh) * | 2011-09-14 | 2014-05-14 | 普罗克斯马根有限公司 | 新的酶抑制剂化合物 |
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| US6982286B2 (en) | 2001-07-12 | 2006-01-03 | Biotie Therapies Corp. | Carbocyclic hydrazino inhibitors of copper-containing amine oxidases |
| US20050096360A1 (en) | 2003-08-08 | 2005-05-05 | Salter-Cid Luisa M. | Inhibitors of semicarbazide-sensitive amine oxidase (SSAO) and VAP-1 mediated adhesion useful for treatment of diseases |
| AU2004270187A1 (en) | 2003-09-04 | 2005-03-17 | Aventis Pharmaceuticals Inc. | Substituted indoles as inhibitors of poly (ADP-ribose) polymerase (PARP) |
| EP2004166A2 (en) | 2006-03-31 | 2008-12-24 | La Jolla Pharmaceutical Company | Inhibitors of semicarbazide-sensitive amine oxidase (ssao) and vap-1 mediated adhesion useful for treatment and prevention of diseases |
| US7947723B2 (en) | 2008-02-01 | 2011-05-24 | Spelman College | Synthesis and anti-proliferative effect of benzimidazole derivatives |
| ES2403633T3 (es) | 2008-12-04 | 2013-05-20 | Proximagen Limited | Compuestos de imidazopiridina |
| WO2010117935A1 (en) | 2009-04-06 | 2010-10-14 | Schering Corporation | Compounds and methods for antiviral treatment |
| EP2518071A1 (en) * | 2011-04-29 | 2012-10-31 | Almirall, S.A. | Imidazopyridine derivatives as PI3K inhibitors |
| IN2014DN01883A (enExample) | 2011-09-14 | 2015-05-15 | Proximagen Ltd | |
| WO2013078254A1 (en) | 2011-11-22 | 2013-05-30 | Array Biopharma Inc. | Bicyclic heteroaryl derivatives as kinase inhibitors |
| GB201304527D0 (en) | 2013-03-13 | 2013-04-24 | Proximagen Ltd | New compounds |
| GB201304526D0 (en) * | 2013-03-13 | 2013-04-24 | Proximagen Ltd | New compounds |
| GB201404498D0 (en) * | 2014-03-13 | 2014-04-30 | Proximagen Ltd | New compounds |
| WO2015189534A1 (en) | 2014-06-12 | 2015-12-17 | Proximagen Limited | Vap-1 inhibitors for treating muscular dystrophy |
| GB201416446D0 (en) | 2014-09-17 | 2014-10-29 | Proximagen Ltd | New enzyme inhibitor compounds |
| JP2019502672A (ja) * | 2015-12-07 | 2019-01-31 | ベネボレンタイ ケンブリッジ リミティド | 疼痛の治療のためのｖａｐ−１阻害剤 |
| GB201709136D0 (en) * | 2017-06-08 | 2017-07-26 | Proximagen Ltd | New therapeutic uses of enzyme inhibitors |
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2014
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Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002038153A1 (en) * | 2000-11-09 | 2002-05-16 | Biovitrum Ab | New use of 4, 5, 6, 7-tetrahydroimidazo-[4,5-c]pyridine derivatives |
| WO2010031791A1 (en) * | 2008-09-16 | 2010-03-25 | Biovitrum Ab (Publ) | New compounds ii |
| CN102232073A (zh) * | 2008-09-16 | 2011-11-02 | 普罗克西梅根有限公司 | 新化合物i |
| CN103180319A (zh) * | 2010-03-15 | 2013-06-26 | 普罗克斯马根有限公司 | 氨基脲敏感性胺氧化酶抑制剂 |
| CN103797012A (zh) * | 2011-09-14 | 2014-05-14 | 普罗克斯马根有限公司 | 新的酶抑制剂化合物 |
Also Published As
| Publication number | Publication date |
|---|---|
| JP6589246B2 (ja) | 2019-10-16 |
| JP2017532315A (ja) | 2017-11-02 |
| WO2016042332A1 (en) | 2016-03-24 |
| HUE045827T2 (hu) | 2020-01-28 |
| BR112017005324A2 (pt) | 2017-12-12 |
| GB201416444D0 (en) | 2014-10-29 |
| DK3194389T3 (da) | 2019-09-09 |
| PL3194389T3 (pl) | 2019-11-29 |
| US20170275281A1 (en) | 2017-09-28 |
| IL251166A0 (en) | 2017-04-30 |
| CA2961424A1 (en) | 2016-03-24 |
| IL251166B (en) | 2020-06-30 |
| AU2015316611A1 (en) | 2017-04-06 |
| US11530208B2 (en) | 2022-12-20 |
| CN107074853A (zh) | 2017-08-18 |
| ES2744548T3 (es) | 2020-02-25 |
| AU2015316611B2 (en) | 2019-05-30 |
| EP3194389B1 (en) | 2019-08-07 |
| PT3194389T (pt) | 2019-09-19 |
| EP3194389A1 (en) | 2017-07-26 |
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