CN107028952A - 用于调节细胞因子活性的方法 - Google Patents

用于调节细胞因子活性的方法 Download PDF

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Publication number
CN107028952A
CN107028952A CN201710153095.4A CN201710153095A CN107028952A CN 107028952 A CN107028952 A CN 107028952A CN 201710153095 A CN201710153095 A CN 201710153095A CN 107028952 A CN107028952 A CN 107028952A
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CN
China
Prior art keywords
hydroxyl
derivative
rudimentary
fatty acid
factor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201710153095.4A
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English (en)
Chinese (zh)
Inventor
上野隆司
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sucampo GmbH
Original Assignee
Sucampo GmbH
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Filing date
Publication date
Application filed by Sucampo GmbH filed Critical Sucampo GmbH
Publication of CN107028952A publication Critical patent/CN107028952A/zh
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/557Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/5575Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/557Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/558Eicosanoids, e.g. leukotrienes or prostaglandins having heterocyclic rings containing oxygen as the only ring hetero atom, e.g. thromboxanes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Transplantation (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CN201710153095.4A 2011-04-19 2012-04-18 用于调节细胞因子活性的方法 Pending CN107028952A (zh)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201161476992P 2011-04-19 2011-04-19
US61/476992 2011-04-19
US201161489516P 2011-05-24 2011-05-24
US61/489516 2011-05-24
US201161537305P 2011-09-21 2011-09-21
US61/537305 2011-09-21
US201161548458P 2011-10-18 2011-10-18
US61/548458 2011-10-18
CN201280030108.4A CN103781482A (zh) 2011-04-19 2012-04-18 用于调节细胞因子活性的方法

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN201280030108.4A Division CN103781482A (zh) 2011-04-19 2012-04-18 用于调节细胞因子活性的方法

Publications (1)

Publication Number Publication Date
CN107028952A true CN107028952A (zh) 2017-08-11

Family

ID=47021806

Family Applications (2)

Application Number Title Priority Date Filing Date
CN201710153095.4A Pending CN107028952A (zh) 2011-04-19 2012-04-18 用于调节细胞因子活性的方法
CN201280030108.4A Pending CN103781482A (zh) 2011-04-19 2012-04-18 用于调节细胞因子活性的方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN201280030108.4A Pending CN103781482A (zh) 2011-04-19 2012-04-18 用于调节细胞因子活性的方法

Country Status (13)

Country Link
US (1) US20120270945A1 (https=)
EP (1) EP2699244A4 (https=)
JP (1) JP2014511825A (https=)
KR (1) KR20140043075A (https=)
CN (2) CN107028952A (https=)
AU (2) AU2012246999A1 (https=)
BR (1) BR112013026644A2 (https=)
CA (1) CA2831869A1 (https=)
IL (1) IL228700A0 (https=)
MX (1) MX2013012251A (https=)
RU (1) RU2013151166A (https=)
TW (1) TW201247615A (https=)
WO (1) WO2012144649A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2642744C (en) * 2006-02-28 2015-02-24 Sucampo Ag Method and composition for treating chronic obstructive pulmonary disease
WO2014159679A1 (en) 2013-03-12 2014-10-02 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Methods for using lubiprostone to absorb fluid from the subretinal space
US20150099802A1 (en) * 2013-10-03 2015-04-09 Sucampo Ag Selective tumor treatment
JP6090723B2 (ja) * 2013-10-04 2017-03-08 国立大学法人東北大学 腎機能障害の予防又は改善剤
US20160120840A1 (en) * 2014-10-30 2016-05-05 Sucampo Ag Method and composition for treating nonerosive reflux disease

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101180096A (zh) * 2005-03-21 2008-05-14 苏坎波公司 用于治疗粘膜疾病的方法和组合物

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5166174A (en) * 1987-01-28 1992-11-24 K.K. Ueno Seiyaku Oyo Kenkyujo Prostaglandins E and anti-ulcers containing same
DK0454429T3 (da) * 1990-04-27 1997-03-17 R Tech Ueno Ltd Anvendelse af 15-dehydroxy-16-oxoprostaglandinderivater til behandling af allergiske sygdomme
JPH0770054A (ja) * 1993-08-30 1995-03-14 R Tec Ueno:Kk 生化学的拮抗および疾患処置剤
CA2150287C (en) * 1994-06-03 2004-08-10 Ryuji Ueno Agent for treating hepato-biliary diseases
JPH1029942A (ja) * 1996-04-02 1998-02-03 Yoichi Ichikawa 慢性関節リウマチ治療剤
DK1841433T3 (da) * 2005-01-27 2012-01-16 Sucampo Ag Præparat til behandling af lidelser i centralnervesystemet
DE602006018583D1 (de) * 2005-03-04 2011-01-13 Sucampo Ag Verfahren und zusammensetzung zur behandlung von peripheren gefässkrankheiten
US20060281818A1 (en) * 2005-03-21 2006-12-14 Sucampo Ag, North Carolina State University Method for treating mucosal disorders
WO2006109881A1 (en) * 2005-04-12 2006-10-19 Sucampo Ag Combined use of prostaglandin compound and proton pump inhibitor for the treatment of gastrointestinal disorders
CA2642744C (en) * 2006-02-28 2015-02-24 Sucampo Ag Method and composition for treating chronic obstructive pulmonary disease
AU2008246579A1 (en) * 2007-05-08 2008-11-13 National University Corporation, Hamamatsu University School Of Medicine Cytotoxic T cell activator comprising EP4 agonist
JPWO2009133863A1 (ja) * 2008-04-28 2011-09-01 国立大学法人浜松医科大学 Ep1アゴニストを含有してなる免疫増強剤
JP2011032262A (ja) * 2009-06-30 2011-02-17 Sucampo Ag Nsaidの長期使用のための医薬組成物
BR112013009163A2 (pt) * 2010-10-15 2016-07-26 Scinopharm Kunshan Biochemical Technology Co Ltd processo para preparação de lubiprostona

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101180096A (zh) * 2005-03-21 2008-05-14 苏坎波公司 用于治疗粘膜疾病的方法和组合物

Also Published As

Publication number Publication date
NZ616027A (en) 2015-09-25
AU2017203276A1 (en) 2017-06-08
RU2013151166A (ru) 2015-05-27
US20120270945A1 (en) 2012-10-25
CA2831869A1 (en) 2012-10-26
CN103781482A (zh) 2014-05-07
WO2012144649A1 (en) 2012-10-26
IL228700A0 (en) 2013-12-31
EP2699244A4 (en) 2014-10-22
BR112013026644A2 (pt) 2016-12-27
EP2699244A1 (en) 2014-02-26
JP2014511825A (ja) 2014-05-19
KR20140043075A (ko) 2014-04-08
TW201247615A (en) 2012-12-01
AU2012246999A1 (en) 2013-10-17
MX2013012251A (es) 2014-01-20

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Application publication date: 20170811