CN106929356A - 滋补肝肾红曲酒及其制备方法 - Google Patents
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Abstract
本发明涉及一种滋补肝肾红曲酒及其制备方法，由下列重量份的原料加工而成：红曲浊酒液1200‑1800份，枸杞提取物50‑80份，谷胱甘肽10‑20份，水溶性葡聚糖20‑30份，中药提取物80‑120份，所述中药提取物由下列重量份的原料加工而成：淮小麦25‑35，柴胡5‑10，川牛膝8‑15，煅牡蛎25‑35，炒土鳖虫10‑20，酸枣仁10‑20，姜半夏8‑15，生地黄25‑35，牡丹皮25‑35，蒲公英25‑35，败酱草15‑25，木贼10‑20，茯苓10‑20，芦根15‑25，麦冬8‑15，陈皮8‑15。本发明的红曲酒中选用的中药提取物配伍合理，作用迅速，起效快，辅以红曲浊酒，口感好，亚健康病人容易接受，方便日常调理，该红曲酒能使肾的经络气血运行畅通，辅以晨练，改善面色少华、神疲乏力和脉沉细的症状，针对性好，疗效显著，2‑3个月即可显著的改善。
Description
技术领域
本发明涉及一种滋补肝肾红曲酒及其制备方法，属于保健酒技术领域。
背景技术
红曲酒经糯米发酵而得，是中国传统名酒，具有消食活血、健脾燥胃的功效；红曲酒的驱寒祛湿功效对于经常腰酸背痛、患有风湿性关节炎的人有极大的益处；红曲酒含有多种人体必需的氨基酸以及维生素，经常饮用能够增强自身的抵抗力；红曲酒还具有降低人体内的胆固醇和血脂含量的作用，可改善血液循环，所有适量的饮用红曲酒具有降血糖、降血压及降血脂的效果。
如今，随着生活和工作压力的日趋增大，众多的中年人士存在肾虚寒湿证，该病症多见于病程长久，阴囊寒冷，睡眠不佳，面色少华，神疲乏力，腰酸腿软，脉沉细。多通过中药来调理，但中药调理存在疗效慢，周期长的缺点，日常服用也不便，口味差，为此本申请的发明人结合红曲酒的特点，设计了一款具有改善肾虚寒湿证的滋补肝肾红曲酒。
发明内容
本发明的目的在于解决现有技术的不足，提供一种滋补肝肾红曲酒及其制备方法，尤其适用于亚健康病人的日常调理。
本发明解决其技术问题所采用的技术方案是：
滋补肝肾红曲酒，所述滋补肝肾酒由下列重量份的原料加工而成：红曲浊酒液1200-1800份，枸杞提取物50-80份，谷胱甘肽10-20份，水溶性葡聚糖20-30份，中药提取物80-120份，所述中药提取物由下列重量份的原料加工而成：淮小麦 25-35，柴胡 5-10，川牛膝8-15，煅牡蛎25-35，炒土鳖虫10-20，酸枣仁10-20，姜半夏8-15，生地黄25-35，牡丹皮25-35，蒲公英25-35，败酱草15-25，木贼10-20，茯苓10-20，芦根15-25，麦冬8-15，陈皮8-15。
淮小麦，【性味与归经】甘，平，入心经。【功效】养心安神。【临床应用】用于神志不宁，失眠等症。
柴胡, 【性味】味辛、苦，性微寒。【归经】归肝、胆、肺经。【功效】和解表里，疏肝解郁，升阳举陷，退热截疟。
川牛膝，【性味】味甘、微苦，性平。【归经】归肝、肾经。【功效】逐瘀通经，通利关节，利尿通淋。
煅牡蛎，【功效】收敛固涩，制酸止痛，重镇安神，软坚散结。
炒土鳖虫，【性味】味咸，性寒。【归经】归肝经。【功效】破血逐瘀，续筋接骨。
酸枣仁，【功效】养肝，宁心，安神，敛汗。
姜半夏，【性味】辛、温；有毒。【归经】归脾、胃、肺经。【功效】降逆止呕。用于呕吐反胃，胸脘痞闷，梅核气。
生地黄，【性味】甘苦，凉。【功效】治阴虚发热，消渴，吐血，衄血，血崩，月经不调，胎动不安，阴伤便秘。
牡丹皮，【性味】苦、辛，微寒。【归经】归心、肝、肾经。【功效】清热凉血，活血化瘀。
蒲公英，【性味】苦甘，寒。【归经】入肝、胃经。【功效】清热解毒，利尿散结。
败酱草，【性味】性凉，味辛、苦。【归经】入胃、大肠、肝经。【功效】清热解毒，祛瘀排脓。
木贼，【性味】甘苦，平。【归经】入肺、肝、胆经。【功效】疏风散热，解肌，退翳。
茯苓，【性味】味甘、淡，性平。【归经】归心、肺、脾、肾经。【功效】利水渗湿，健脾，宁心。
芦根，【性味】甘，寒。【归经】归肺经、胃经。【功效】清热生津，除烦，止呕，利尿。
麦冬，生津解渴、润肺止咳之效。
陈皮，【性味】味苦、辛，性温。【归经】归肺、脾经。【功效】理气健脾，燥湿化痰。
本发明的红曲酒中选用的中药提取物配伍合理，作用迅速，起效快，辅以红曲浊酒，口感好，亚健康病人容易接受，方便日常调理，该红曲酒能使肾的经络气血运行畅通，辅以晨练，改善面色少华、神疲乏力和脉沉细的症状，针对性好，疗效显著，2-3个月即可显著的改善。
本申请的发明人实践中发现，本发明的红曲酒8-10℃一般可以放置6个月，存储时间再延长就会产生色变，固形物沉淀，大量活性成分会析出积聚，为了解决这一技术问题，本申请的发明人通过大量实践，发现添加适量的还原型谷胱甘肽和水溶性葡聚糖，能很好的解决这一技术问题，还原型谷胱甘肽具有良好的抗氧化性和抗色变性能，水溶性葡聚糖作为大分子，具有良好的水溶性、分散性和稳定性，起到稳定剂的作用，使得红曲酒各活性成分形成稳定的分散体系，避免积聚。大大延长存储时间，8-10℃一般可以放置9个月。
优选的，所述滋补肝肾酒由下列重量份的原料加工而成：红曲浊酒液1500份，枸杞提取物60份，谷胱甘肽15份，水溶性葡聚糖25份，中药提取物100份。
优选的，所述中药提取物由下列重量份的原料加工而成：淮小麦 28-32，柴胡 6-8，川牛膝9-12，煅牡蛎25-30，炒土鳖虫12-18，酸枣仁12-18，姜半夏8-12，生地黄28-32，牡丹皮28-32，蒲公英28-32，败酱草15-20，木贼12-15，茯苓12-18，芦根15-20，麦冬10-12，陈皮10-12。
优选的，淮小麦 30，柴胡 6，川牛膝10，煅牡蛎30，炒土鳖虫15，酸枣仁15，姜半夏9，生地黄30， 牡丹皮30，蒲公英30，败酱草20，木贼15，茯苓15，芦根20，麦冬10，陈皮10。
一种滋补肝肾红曲酒的制备方法，所述制备方法步骤如下：
S1:制备中药提取物，
（1）预煎煮：将配方量的煅牡蛎，加入适量的水，煎煮20min以上，
（2）煎煮：将配方量的淮小麦、柴胡 、川牛膝、炒土鳖虫、酸枣仁、姜半夏、生地黄、牡丹皮、蒲公英、败酱草、木贼、茯苓、芦根、麦冬和陈皮，用适量的水浸泡，步骤（1）预煎煮完成后，连料带水加入其中，继续煎煮30min-2h以上；
（3）离心过滤：煎煮完成后离心滤去药渣，药液经浓缩干燥获得干粉；
S2：制备红曲酒，
将配方量的枸杞提取物、谷胱甘肽、水溶性葡聚糖和中药提取物混合均匀，然后逐步加入配方量的红曲浊酒中，边加边搅拌，直至充分溶解，然后过滤去除杂质，再经灭菌、灌装即可。
本发明的有益效果是：本发明的红曲酒中选用的中药提取物配伍合理，作用迅速，起效快，辅以红曲浊酒，口感好，亚健康病人容易接受，方便日常调理，该红曲酒能使肾的经络气血运行畅通，辅以晨练，改善面色少华、神疲乏力和脉沉细的症状，针对性好，疗效显著，2-3个月即可显著的改善。
具体实施方式
下面通过具体实施例，对本发明的技术方案作进一步的具体说明。
实施例1：
滋补肝肾红曲酒，所述滋补肝肾酒由下列重量份的原料加工而成：红曲浊酒液1200份，枸杞提取物50份，谷胱甘肽10份，水溶性葡聚糖20份，中药提取物80份，所述中药提取物由下列重量份的原料加工而成：淮小麦 25，柴胡 5，川牛膝8，煅牡蛎25，炒土鳖虫10，酸枣仁10，姜半夏8，生地黄25，牡丹皮25，蒲公英25，败酱草15，木贼10，茯苓10，芦根15，麦冬8，陈皮8；
其制备方法步骤如下： S1:制备中药提取物，
（1）预煎煮：将配方量的煅牡蛎，加入适量的水，煎煮20min以上，
（2）煎煮：将配方量的淮小麦、柴胡 、川牛膝、炒土鳖虫、酸枣仁、姜半夏、生地黄、牡丹皮、蒲公英、败酱草、木贼、茯苓、芦根、麦冬和陈皮，用适量的水浸泡，步骤（1）预煎煮完成后，连料带水加入其中，继续煎煮2h以上；
（3）离心过滤：煎煮完成后离心滤去药渣，药液经浓缩干燥获得干粉；
S2：制备红曲酒，
将配方量的枸杞提取物、谷胱甘肽、水溶性葡聚糖和中药提取物混合均匀，然后逐步加入配方量的红曲浊酒中，边加边搅拌，直至充分溶解，然后过滤去除杂质，再经灭菌、灌装即可。
实施例2：
滋补肝肾红曲酒，所述滋补肝肾酒由下列重量份的原料加工而成：红曲浊酒液1800份，枸杞提取物80份，谷胱甘肽20份，水溶性葡聚糖30份，中药提取物120份，所述中药提取物由下列重量份的原料加工而成：淮小麦 35，柴胡 10，川牛膝15，煅牡蛎35，炒土鳖虫20，酸枣仁20，姜半夏15，生地黄35，牡丹皮35，蒲公英35，败酱草25，木贼20，茯苓20，芦根25，麦冬15，陈皮15；
其制备方法步骤如下： S1:制备中药提取物，
（1）预煎煮：将配方量的煅牡蛎，加入适量的水，煎煮20min以上，
（2）煎煮：将配方量的淮小麦、柴胡 、川牛膝、炒土鳖虫、酸枣仁、姜半夏、生地黄、牡丹皮、蒲公英、败酱草、木贼、茯苓、芦根、麦冬和陈皮，用适量的水浸泡，步骤（1）预煎煮完成后，连料带水加入其中，继续煎煮2h以上；
（3）离心过滤：煎煮完成后离心滤去药渣，药液经浓缩干燥获得干粉；
S2：制备红曲酒，
将配方量的枸杞提取物、谷胱甘肽、水溶性葡聚糖和中药提取物混合均匀，然后逐步加入配方量的红曲浊酒中，边加边搅拌，直至充分溶解，然后过滤去除杂质，再经灭菌、灌装即可。
实施例3：
滋补肝肾红曲酒，所述滋补肝肾酒由下列重量份的原料加工而成：红曲浊酒液1500份，枸杞提取物60份，谷胱甘肽15份，水溶性葡聚糖25份，中药提取物100份，所述中药提取物由下列重量份的原料加工而成：淮小麦 30，柴胡 6，川牛膝10，煅牡蛎30，炒土鳖虫15，酸枣仁15，姜半夏9，生地黄30， 牡丹皮30，蒲公英30，败酱草20，木贼15，茯苓15，芦根20，麦冬10，陈皮10；
其制备方法步骤如下：
S1:制备中药提取物，
（1）预煎煮：将配方量的煅牡蛎，加入适量的水，煎煮20min以上，
（2）煎煮：将配方量的淮小麦、柴胡 、川牛膝、炒土鳖虫、酸枣仁、姜半夏、生地黄、牡丹皮、蒲公英、败酱草、木贼、茯苓、芦根、麦冬和陈皮，用适量的水浸泡，步骤（1）预煎煮完成后，连料带水加入其中，继续煎煮1h以上；
（3）离心过滤：煎煮完成后离心滤去药渣，药液经浓缩干燥获得干粉；
S2：制备红曲酒，
将配方量的枸杞提取物、谷胱甘肽、水溶性葡聚糖和中药提取物混合均匀，然后逐步加入配方量的红曲浊酒中，边加边搅拌，直至充分溶解，然后过滤去除杂质，再经灭菌、灌装即可。
本发明实施例1-3的红曲酒，早饭后25ml，晚饭后50ml，连续服用3个疗程（三个月），调理期间每天晨跑30-45min，辅助调理。
临床试验：临床120例，符合肾虚寒湿证，均来源于门诊病例，年龄40-55岁，其中男性60例，女性60例，平均年龄45岁。随机分成五组，每组40例，按照上述方法分别使用实施例1-3的红曲酒调理亚健康，三个疗程后进行疗效评价。
疗效判断标准：以症状改变程度为疗效判定标准。
观察结果：临床症状消失90例，临床症状显著改善22例，临床症状无改善8例，总有效率93.3%。所有使用者均无不良反应， 2年后回访复查，无复发。
以上所述的实施例只是本发明的一种较佳的方案，并非对本发明作任何形式上的限制，在不超出权利要求所记载的技术方案的前提下还有其它的变体及改型。
Claims (5)
1.滋补肝肾红曲酒，其特征在于：所述滋补肝肾酒由下列重量份的原料加工而成：红曲浊酒液1200-1800份，枸杞提取物50-80份，谷胱甘肽10-20份，水溶性葡聚糖20-30份，中药提取物80-120份，所述中药提取物由下列重量份的原料加工而成：淮小麦 25-35，柴胡 5-10，川牛膝8-15，煅牡蛎25-35，炒土鳖虫10-20，酸枣仁10-20，姜半夏8-15，生地黄25-35，牡丹皮25-35，蒲公英25-35，败酱草15-25，木贼10-20，茯苓10-20，芦根15-25，麦冬8-15，陈皮8-15。
2.根据权利要求1所述的滋补肝肾红曲酒，其特征在于：所述滋补肝肾酒由下列重量份的原料加工而成：红曲浊酒液1500份，枸杞提取物60份，谷胱甘肽15份，水溶性葡聚糖25份，中药提取物100份。
3.根据权利要求1或2所述的滋补肝肾红曲酒，其特征在于：所述中药提取物由下列重量份的原料加工而成：淮小麦 28-32，柴胡 6-8，川牛膝9-12，煅牡蛎25-30，炒土鳖虫12-18，酸枣仁12-18，姜半夏8-12，生地黄28-32，牡丹皮28-32，蒲公英28-32，败酱草15-20，木贼12-15，茯苓12-18，芦根15-20，麦冬10-12，陈皮10-12。
4.根据权利要求3所述的滋补肝肾红曲酒，其特征在于：淮小麦 30，柴胡 6，川牛膝10，煅牡蛎30，炒土鳖虫15，酸枣仁15，姜半夏9，生地黄30， 牡丹皮30，蒲公英30，败酱草20，木贼15，茯苓15，芦根20，麦冬10，陈皮10。
5.一种权利要求1所述的滋补肝肾红曲酒的制备方法，其特征在于：所述制备方法步骤如下：
S1:制备中药提取物，
（1）预煎煮：将配方量的煅牡蛎，加入适量的水，煎煮20min以上，
（2）煎煮：将配方量的淮小麦、柴胡 、川牛膝、炒土鳖虫、酸枣仁、姜半夏、生地黄、牡丹皮、蒲公英、败酱草、木贼、茯苓、芦根、麦冬和陈皮，用适量的水浸泡，步骤（1）预煎煮完成后，连料带水加入其中，继续煎煮30min-2h以上；
（3）离心过滤：煎煮完成后离心滤去药渣，药液经浓缩干燥获得干粉；
S2：制备红曲酒，
将配方量的枸杞提取物、谷胱甘肽、水溶性葡聚糖和中药提取物混合均匀，然后逐步加入配方量的红曲浊酒中，边加边搅拌，直至充分溶解，然后过滤去除杂质，再经灭菌、灌装即可。
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