CN106924671A - A kind of newborn addiction dispersing paste and preparation method thereof - Google Patents

A kind of newborn addiction dispersing paste and preparation method thereof Download PDF

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CN106924671A
CN106924671A CN201710224970.3A CN201710224970A CN106924671A CN 106924671 A CN106924671 A CN 106924671A CN 201710224970 A CN201710224970 A CN 201710224970A CN 106924671 A CN106924671 A CN 106924671A
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parts
root
chinese medicine
medicine composition
plaster
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CN106924671B (en
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买莹莹
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9066Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/55Glands not provided for in groups A61K35/22 - A61K35/545, e.g. thyroids, parathyroids or pineal glands
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/233Bupleurum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236Ligusticum (licorice-root)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286Carthamus (distaff thistle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/32Burseraceae (Frankincense family)
    • A61K36/324Boswellia, e.g. frankincense
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/32Burseraceae (Frankincense family)
    • A61K36/328Commiphora, e.g. mecca myrrh or balm of Gilead
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/536Prunella or Brunella (selfheal)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537Salvia (sage)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/58Meliaceae (Chinaberry or Mahogany family), e.g. Azadirachta (neem)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/65Paeoniaceae (Peony family), e.g. Chinese peony
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/66Papaveraceae (Poppy family), e.g. bloodroot
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8966Fritillaria, e.g. checker lily or mission bells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms

Abstract

The present invention relates to a kind of newborn addiction dispersing paste and preparation method thereof, it is made up of plaster substrate and Chinese medicine composition, and the weight ratio of the plaster substrate and Chinese medicine composition is 8:1.5‑2.5;The Chinese medicine composition is made up of the raw material of following weight parts:35 parts of radix bupleuri, 35 parts of frankincense, 35 parts of myrrh, 35 parts of Ligusticum wallichii, 35 parts of root tuber of aromatic turmeric, 35 parts of the root of herbaceous peony, 35 parts of fritillaria thunbergii, 35 parts of pangolin, 05 parts of corydalis tuber, 05 parts of the red sage root, 05 parts of safflower, 05 parts of selfheal, 05 parts of Fructus meliae toosendan, 0 0.012 parts of Moschus.Newborn addiction dispersing paste disclosed in this invention and preparation method thereof, the simple but drug effect of the plaster composition is notable, various Breast Nodules can be treated, cream the effective elements of the medicine can be sent directly into inside breast tissue by skin pore, effective ingredient can be completely absorbed, and matrix, completely without excitant, patient acceptability is strong.

Description

A kind of newborn addiction dispersing paste and preparation method thereof
Technical field
The present invention relates to a kind of traditional Chinese medicine plaster, and in particular to a kind of newborn addiction dispersing paste and preparation method thereof.
Background technology
Breast Nodules are common female gynecological diseases, are exactly disease of hyperplasia of mammary glands glands, are a kind of noninflammatory diseases of non-tumour Disease, is common in the women of child-bearing period.Breast Nodules mainly have 4 types:1st, (puberty is premenstrual, menstrual period pain, without swollen for mastodynia Block, disappears after);2nd, hyperplasia of mammary glands (20-35 Sui, premenstrual pain, with the multiple lesser tubercle of trip, is alleviated after);3rd, fiber Adenoma or papilloma (single-shot lump, border is clear, and activity is big, without pain, adhesion);4th, cystic hyperplasia of mammary gland or hardening mammary gland (multiple lesser tubercles, in flakes, matter is tough, obscure boundary, is often bilateral, and light tenderness has with the menstrual cycle for disease
Close.The Symptoms of Breast Nodules are mainly swollen breasts and lump in breast:1. swollen breasts:It is common for unilateral or Bilateral swollen breasts or tenderness, the general course of disease be 2 months to the several years, the characteristics of Most patients have periodicity pain; 2. lump in breast:Lump is often multiple, unilateral or bilateral, common with outside upper quadrant;And size, quality also can be with menstruations In cyclically-varying, the increase of premenstrua lump, quality is harder, and mass reduction after menstruation, matter is tough without hard.Lay one's hand on accessible when looking into Lump is in nodule structure, not of uniform size, unclear with surrounding tissue boundary, there is tenderness more, with skin and deep tissue without adhesion, can quilt Promote, axillary gland not enlargement.In addition, the symptom of Breast Nodules also has, the course of disease is more long, slower development, can have nipple to overflow sometimes Liquid etc. is showed.
So far, the treatment by Chinese herbs prescription of existing more than 90 kinds of Breast Nodules is made known publicly.For example CN200310105406.8 discloses a kind of externally applied plaster for treating the proliferation of mammary gland, hyperplasia of mammary glands, cystic hyperplasia of mammary gland, its by Deer horn glue, thizoma curculiginis, Morinda officinalis, the root of three-nerved spicebush, full Snakegourd Fruit, honeycomb, the capsule of weeping forsythia, centipede, camphor, rheum officinale, styrax, edible tulip, agalloch eaglewood, pass Akebi, semen brassicae, Moschus etc. are made.CN200810137512.7 discloses a kind of plaster for treating cyclomastopathy and preparation side Method, its by corydalis tuber 12, turtle shell 8, ground bettle 10, pangolin 8, oyster 8, leech 8, earthworm 10, cassia twig 2, Chinese herbaceous peony 2, glutinous rehmannia 2, The root bark of tree peony 2, peach kernel 2, rheum officinale 4, Rhizoma Sparganii 2, curcuma zedoary 2, marine alga 2, kelp 2, selfheal 2, myrrh 2, dragon's blood 2, frankincense 2, amber 4, ice 2 parts of piece is made;These Chinese prescriptions mostly complicated component;And due to the barrier action of dermal tissue, Chinese medicine in formula into Part be difficult to by breast top layer permeate affected part repair block, the cell of necrosis, hyperplasia lump is softened, scattered silt, it is impossible to logical Cross skin pore to be sent directly into inside breast tissue, effective ingredient is not fully absorbed, absorption difference;In addition, the stimulation of matrix Property it is also larger, if do not noted using easily causing red swelling of the skin, fester.
The content of the invention
The purpose of the present invention is to propose to a kind of newborn addiction dispersing paste and preparation method thereof, the simple but drug effect of the plaster composition shows Write, various Breast Nodules can be treated, cream the effective elements of the medicine can be sent directly into inside breast tissue by skin pore, effectively Composition can be completely absorbed, and matrix, completely without excitant, patient acceptability is strong.
The purpose of the present invention is following technical proposals to be realized:
A kind of newborn addiction dispersing paste, it is made up of plaster substrate and Chinese medicine composition, the plaster substrate and Chinese medicine composition Weight ratio be 8:1.5-2.5;The Chinese medicine composition is made up of the raw material of following weight parts:Radix bupleuri 3-5 parts, frankincense 3-5 parts, Myrrh 3-5 parts, Ligusticum wallichii 3-5 parts, root tuber of aromatic turmeric 3-5 parts, root of herbaceous peony 3-5 parts, fritillaria thunbergii 3-5 parts, pangolin 3-5 parts, corydalis tuber 0-5 parts, Red sage root 0-5 parts, safflower 0-5 parts, selfheal 0-5 parts, Fructus meliae toosendan 0-5 parts, Moschus 0-0.012 parts.
Further, the weight portion of each raw material is in the Chinese medicine composition:Radix bupleuri 3-5 parts, frankincense 3-5 parts, myrrh 3-5 Part, Ligusticum wallichii 3-5 parts, root tuber of aromatic turmeric 3-5 parts, root of herbaceous peony 3-5 parts, fritillaria thunbergii 3-5 parts, pangolin 3-5 parts, corydalis tuber 3-5 parts, red sage root 3-5 Part, safflower 3-5 parts, selfheal 3-5 parts, Fructus meliae toosendan 3-5 parts, 0.01 part of Moschus.
Further, the weight portion of each raw material is in the Chinese medicine composition:Radix bupleuri 3.5-4.5 parts, frankincense 3.5-4.5 Part, myrrh 3.5-4.5 parts, Ligusticum wallichii 3.5-4.5 parts, root tuber of aromatic turmeric 3.5-4.5 parts, root of herbaceous peony 3.5-4.5 parts, fritillaria thunbergii 3.5-4.5 parts, wear Naze 3.5-4.5 parts, prolong 3.5 rope 3.5-4.5 parts recklessly, red sage root 3.5-4.5 parts, safflower 3.5-4.5 parts, selfheal 3.5-4.5 parts, Fructus meliae toosendan 3.5-4.54.5 parts, 0.01 part of Moschus.
Further, the weight portion 4.5 of each raw material is in the Chinese medicine composition:Each raw material in the Chinese medicine composition Weight portion is:4 parts of radix bupleuri, 4 parts of frankincense, 4 parts of myrrh, 3.5 4 parts of Ligusticum wallichiis, 4 parts of root tuber of aromatic turmeric, 4 parts of the root of herbaceous peony, 4 parts of fritillaria thunbergii, pangolin 4 Part, 4 parts of corydalis tuber, red 44 parts of ginseng, 4 parts of safflower, 4 parts of selfheal, 4 parts of Fructus meliae toosendan, 0.01 part of Moschus.
Further, the weight ratio of the plaster substrate and Chinese medicine composition is 4:1.
Further, the plaster substrate is black plaster matrix.
Further, the red sage root is replaced with pseudo-ginseng.
The preparation method of above-mentioned newborn addiction dispersing paste, comprises the steps:
(1) each raw material is weighed by weight;
(2) red sage root or pseudo-ginseng are ground into powder;
(3) by radix bupleuri, frankincense, myrrh, Ligusticum wallichii, root tuber of aromatic turmeric, the root of herbaceous peony, fritillaria thunbergii, pangolin, corydalis tuber, safflower, selfheal, Fructus meliae toosendan and Moschus are respectively crushed into powder;
(4) each material powder in step (2) and step (3) in addition to Moschus is uniformly mixed;
(5) powder and Moschus that will be mixed in step (4) are well mixed by equal increments method;
(6) plaster substrate is heated to fusing, is then mixed in step (5) is added in the state of plaster substrate is in fusing Even powder, and stir, then stop heating, cool down to obtain finished product plaster.
Further, it is that each raw material is respectively crushed into impalpable powder in the step (2) and step (3).
Further, plaster substrate is 80 DEG C -82 DEG C in the temperature that molten state need to keep in the step (5).
The action principle of the newborn addiction dispersing paste in the present invention:
Newborn addiction dispersing paste of the invention, is that, by radix bupleuri, frankincense, myrrh, Ligusticum wallichii, root tuber of aromatic turmeric, the root of herbaceous peony, fritillaria thunbergii, pangolin prolongs Hu Suo, the red sage root (or pseudo-ginseng), safflower, selfheal, Fructus meliae toosendan and Moschus are constituted;Wherein, radix bupleuri, frankincense, myrrh, Ligusticum wallichii, root tuber of aromatic turmeric, The root of herbaceous peony, fritillaria thunbergii, pangolin is necessary component;Corydalis tuber, the red sage root (or pseudo-ginseng), safflower, selfheal, Fructus meliae toosendan and Moschus are non- Necessary component.Radix bupleuri soothing liver-qi stagnation be monarch drug in a prescription, Ligusticum wallichii, root tuber of aromatic turmeric promoting blood circulation and stopping pain and have promoting the circulation of qi work(be ministerial drug;Root of herbaceous peony nourishing blood and liver, Irritability is able to bar and reaches, and gas row is then tied and disappeared;Fritillaria thunbergii, pangolin dissipating bind promoting blood circulation and removing obstruction in channels;Frankincense, myrrh promoting blood circulation and stopping pain simultaneously have detumescence Work(;5 with corydalis tuber, the red sage root (or pseudo-ginseng), safflower, Fructus meliae toosendan and Moschus strengthening work(promoting blood circulation and removing blood stasis, then 5 clear with selfheal Hot purging intense heat, the work(of mass dissipating and swelling eliminating;All medicines share plays the work(of soothing liver-qi stagnation, dispersing swelling and dissipating binds, promoting blood circulation and stopping pain altogether.
The beneficial effects of the present invention are:
(1) newborn addiction dispersing paste of the invention, has functions that soothing liver-qi stagnation, dispersing swelling and dissipating binds, promoting blood circulation and stopping pain.Tested through clinic Card, the plaster in the present invention can reach 93% to the effective percentage of the treatment of various Breast Nodules, and cure rate can reach 80%, The simple but drug effect of prescription is notable.
(2) the newborn addiction dispersing paste in the present invention, the Chinese medicinal ingredients in formula can permeate affected part and repair by breast top layer Blocking, the cell of necrosis, soften to hyperplasia lump, and scattered silt, cream the effective elements of the medicine is to be sent directly into mammary gland by skin pore Organization internal, effective ingredient can be completely absorbed.
(3) the newborn addiction dispersing paste in the present invention, using black plaster matrix, black plaster matrix is completely without excitant, patient It is acceptable strong.
Specific embodiment
To make the object, technical solutions and advantages of the present invention clearer, technical scheme will be carried out below Detailed description.Obviously, described embodiment is only a part of embodiment of the invention, rather than whole embodiments.Base Embodiment in the present invention, those of ordinary skill in the art are resulting on the premise of creative work is not made to be owned Other embodiment, belongs to the scope that the present invention is protected.
First, embodiment is prepared:
Prepare embodiment 1:
1.1 formulas:A kind of newborn addiction dispersing paste, it is made up of black plaster matrix and Chinese medicine composition, the black plaster matrix It is 4 with the weight ratio of Chinese medicine composition:1.The Chinese medicine composition is made up of the raw material of following weight parts:4 parts of radix bupleuri, frankincense 4 Part, 4 parts of myrrh, 4 parts of Ligusticum wallichii, 4 parts of root tuber of aromatic turmeric, 4 parts of the root of herbaceous peony, 4 parts of fritillaria thunbergii, 4 parts of pangolin, 4 parts of corydalis tuber, 4 parts of the red sage root, safflower 4 parts, 4 parts of selfheal, 4 parts of Fructus meliae toosendan, 0.01 part of Moschus;Black plaster matrix is 208.04 parts.
The plaster in the 1Kg present invention is prepared, the consumption of each raw material is:Radix bupleuri 15.38g, frankincense 15.38g, myrrh 15.38g, Ligusticum wallichii 15.38g, root tuber of aromatic turmeric 15.38g, root of herbaceous peony 15.38g, fritillaria thunbergii 15.38g, pangolin 15.38g, corydalis tuber 15.38g, red sage root 15.38g, safflower 15.38g, selfheal 15.38g, Fructus meliae toosendan 15.38g, Moschus 0.04g;Black plaster matrix is 800g。
1.2 preparation methods, comprise the steps:
(1) each raw material is weighed by above-mentioned weight;
(2) by the red sage root, radix bupleuri, frankincense, myrrh, Ligusticum wallichii, root tuber of aromatic turmeric, the root of herbaceous peony, fritillaria thunbergii, pangolin, corydalis tuber, safflower, summer Withered grass, Fructus meliae toosendan and Moschus are respectively crushed into impalpable powder;
(3) each material powder in step (2) in addition to Moschus is uniformly mixed;
(4) powder and Moschus that will be mixed in step (3) are well mixed by equal increments method;
(5) black plaster matrix is heated to 80 DEG C -82 DEG C, after black plaster is ma trix melting, is in black plaster matrix molten The powder mixed in step (4) is added in the state of change, and is stirred, then stop heating, cool down to obtain finished product plaster.
Prepare embodiment 2:
2.1 formulas:A kind of newborn addiction dispersing paste, it is made up of black plaster matrix and Chinese medicine composition, the black plaster matrix It is 8 with the weight ratio of Chinese medicine composition:1.5.The Chinese medicine composition is made up of the raw material of following weight parts:3 parts of radix bupleuri, frankincense 5 parts, 5 parts of myrrh, 3 parts of Ligusticum wallichii, 3 parts of root tuber of aromatic turmeric, 3 parts of the root of herbaceous peony, 5 parts of fritillaria thunbergii, 3 parts of pangolin;Black plaster matrix is 160 parts.
The plaster in the 1Kg present invention is prepared, the consumption of each raw material is:Radix bupleuri 15.79g, frankincense 26.32g, myrrh 26.32g, Ligusticum wallichii 15.79g, root tuber of aromatic turmeric 15.79g, root of herbaceous peony 15.79g, fritillaria thunbergii 26.32g, pangolin 15.79g;Black plaster matrix It is 842.11g.
2.2 preparation methods, comprise the steps:
(1) each raw material is weighed by above-mentioned weight;
(2) radix bupleuri, frankincense, myrrh, Ligusticum wallichii, root tuber of aromatic turmeric, the root of herbaceous peony, fritillaria thunbergii and pangolin are respectively crushed into impalpable powder;
(3) each material powder in step (2) in addition to Moschus is uniformly mixed;
(4) black plaster matrix is heated to 80 DEG C -82 DEG C, after black plaster is ma trix melting, is in black plaster matrix molten The powder mixed in step (3) is added in the state of change, and is stirred, then stop heating, cool down to obtain finished product plaster.
Prepare embodiment 3:
3.1 formulas:A kind of newborn addiction dispersing paste, it is made up of black plaster matrix and Chinese medicine composition, the black plaster matrix It is 4 with the weight ratio of Chinese medicine composition:1.The Chinese medicine composition is made up of the raw material of following weight parts:5 parts of radix bupleuri, frankincense 3 Part, 3 parts of myrrh, 5 parts of Ligusticum wallichii, 5 parts of root tuber of aromatic turmeric, 5 parts of the root of herbaceous peony, 3 parts of fritillaria thunbergii, 5 parts of pangolin, 3 parts of corydalis tuber, 5 parts of pseudo-ginseng, safflower 3 parts, 3 parts of selfheal, 5 parts of Fructus meliae toosendan, 0.01 part of Moschus;Black plaster matrix is 185.63 parts.
The plaster in the 1Kg present invention is prepared, the consumption of each raw material is:Radix bupleuri 20.95g, frankincense 12.57g, myrrh 12.57g, Ligusticum wallichii 20.95g, root tuber of aromatic turmeric 20.95g, root of herbaceous peony 20.95g, fritillaria thunbergii 12.57g, pangolin 20.95g, corydalis tuber 12.57g, pseudo-ginseng 20.95g, safflower 12.57g, selfheal 12.57g, Fructus meliae toosendan 20.95g, Moschus 0.04g;Black plaster matrix is 777.87g。
3.2 preparation methods, comprise the steps:
(1) each raw material is weighed by above-mentioned weight;
(2) by pseudo-ginseng, radix bupleuri, frankincense, myrrh, Ligusticum wallichii, root tuber of aromatic turmeric, the root of herbaceous peony, fritillaria thunbergii, pangolin, corydalis tuber, safflower, summer Withered grass, Fructus meliae toosendan and Moschus are respectively crushed into impalpable powder;
(3) each material powder in step (2) in addition to Moschus is uniformly mixed;
(4) powder and Moschus that will be mixed in step (3) are well mixed by equal increments method;
(5) black plaster matrix is heated to 80 DEG C -82 DEG C, after black plaster is ma trix melting, is in black plaster matrix molten The powder mixed in step (4) is added in the state of change, and is stirred, then stop heating, cool down to obtain finished product plaster.
Prepare embodiment 4:
4.1 formulas:A kind of newborn addiction dispersing paste, it is made up of black plaster matrix and Chinese medicine composition, the black plaster matrix It is 4 with the weight ratio of Chinese medicine composition:1.The Chinese medicine composition is made up of the raw material of following weight parts:3.5 parts of radix bupleuri, frankincense 4 parts, 4.5 parts of myrrh, 4.5 parts of Ligusticum wallichii, 4 parts of root tuber of aromatic turmeric, 4 parts of the root of herbaceous peony, 3.5 parts of fritillaria thunbergii, 3.5 parts of pangolin, 4.5 parts of corydalis tuber, 3.5 parts of the red sage root, 4 parts of safflower, 4 parts of selfheal, 3.5 parts of Fructus meliae toosendan, 0.01 part of Moschus;Black plaster matrix is 204.04 parts.
The plaster in the 1Kg present invention is prepared, the consumption of each raw material is:Radix bupleuri 13.72g, frankincense 15.68g, myrrh 17.64g, Ligusticum wallichii 17.64g, root tuber of aromatic turmeric 15.68g, root of herbaceous peony 15.68g, fritillaria thunbergii 13.72g, pangolin 13.72g, corydalis tuber 17.64g, red sage root 13.72g, safflower 15.68g, selfheal 15.68g, Fructus meliae toosendan 13.72g, Moschus 0.04g;Black plaster matrix is 800g。
4.2 preparation methods, comprise the steps:
(1) each raw material is weighed by above-mentioned weight;
(2) by the red sage root, radix bupleuri, frankincense, myrrh, Ligusticum wallichii, root tuber of aromatic turmeric, the root of herbaceous peony, fritillaria thunbergii, pangolin, corydalis tuber, safflower, summer Withered grass, Fructus meliae toosendan and Moschus are respectively crushed into impalpable powder;
(3) each material powder in step (2) in addition to Moschus is uniformly mixed;
(4) powder and Moschus that will be mixed in step (3) are well mixed by equal increments method;
(5) black plaster matrix is heated to 80 DEG C -82 DEG C, after black plaster is ma trix melting, is in black plaster matrix molten The powder mixed in step (4) is added in the state of change, and is stirred, then stop heating, cool down to obtain finished product plaster.
Prepare embodiment 5:
5.1 formulas:A kind of newborn addiction dispersing paste, it is made up of black plaster matrix and Chinese medicine composition, the black plaster matrix It is 4 with the weight ratio of Chinese medicine composition:1.The Chinese medicine composition is made up of the raw material of following weight parts:3.5 parts of radix bupleuri, frankincense 4.5 parts, 3 parts of myrrh, 5 parts of Ligusticum wallichii, 5 parts of root tuber of aromatic turmeric, 3 parts of the root of herbaceous peony, 4.5 parts of fritillaria thunbergii, 4 parts of pangolin, 3 parts of pseudo-ginseng, safflower 3.5 Part, 4 parts of selfheal, 0.01 part of Moschus;Black plaster matrix is 172.04 parts.
The plaster in the 1Kg present invention is prepared, the consumption of each raw material is:Radix bupleuri 16.28g, frankincense 20.93g, myrrh 13.95g, Ligusticum wallichii 23.25g, root tuber of aromatic turmeric 23.25g, root of herbaceous peony 13.95g, fritillaria thunbergii 20.93g, pangolin 18.60g, pseudo-ginseng 13.95g, Safflower 16.28g, selfheal 18.60g, Moschus 0.05g;Black plaster matrix is 800g.
5.2 preparation methods, comprise the steps:
(1) each raw material is weighed by above-mentioned weight;
(2) by pseudo-ginseng, radix bupleuri, frankincense, myrrh, Ligusticum wallichii, root tuber of aromatic turmeric, the root of herbaceous peony, fritillaria thunbergii, pangolin, safflower, selfheal and musk deer Perfume (or spice) is respectively crushed into impalpable powder;
(3) each material powder in step (2) in addition to Moschus is uniformly mixed;
(4) powder and Moschus that will be mixed in step (3) are well mixed by equal increments method;
(5) black plaster matrix is heated to 80 DEG C -82 DEG C, after black plaster is ma trix melting, is in black plaster matrix molten The powder mixed in step (4) is added in the state of change, and is stirred, then stop heating, cool down to obtain finished product plaster.
2nd, test example:
1st, clinical test:
1) physical data:To 500 various Breast Nodules case clinical observations, the wherein age is minimum 24 years old, maximum 65 years old.
2) treatment method:The plaster affected part prepared in embodiment 1,1 time for each person every day, every time one are prepared with the present invention Patch.
3) efficacy assessment standard:
Cure:Clinical symptoms are wholly absent, and pain and sense of discomfort are wholly absent, and recover normal life.
Effectively:Entirely or essentially symptom is substantially eliminated, and pain and sense of discomfort substantially disappear, but there is also slight disease Shape, only part recovery normal life.
It is invalid:Symptom, sign are without significant change.
4) treatment results:Treatment results are as shown in table 1:
Table 1
Total number of cases Cure Effectively It is invalid It is efficient
500 400 65 35 93%
5) typical clinical case:
1., Zhang, female 50 years old, starts to suffer from Breast Nodules for 2000, and illness continues 16 years, with this medicine 60 days after, symptom disappears Lose.
2., Wei, female 45 years old, starts to suffer from Breast Nodules for 2010, and illness continues 6 years, with this medicine 50 days after, symptom disappears Lose.
Can be seen that the present invention prepares treatment of the plaster prepared in embodiment 1 to Breast Nodules by above-mentioned clinical test Effective percentage can reach 93%, cure rate can reach 80%.Certainly, using preparation in present invention preparation embodiment 2-5 Plaster treatment Breast Nodules have and prepare the same therapeutic effect of embodiment 1.
The above, specific embodiment only of the invention, but protection scope of the present invention is not limited thereto, and it is any Those familiar with the art the invention discloses technical scope in, change or replacement can be readily occurred in, should all contain Cover within protection scope of the present invention.Therefore, protection scope of the present invention should be based on the protection scope of the described claims.

Claims (10)

1. a kind of newborn addiction dispersing paste, it is characterised in that:It is made up of plaster substrate and Chinese medicine composition, and the plaster substrate is with The weight ratio of drug composition is 8:1.5-2.5;The Chinese medicine composition is made up of the raw material of following weight parts:Radix bupleuri 3-5 parts, breast It is fragrant 3-5 parts, myrrh 3-5 parts, Ligusticum wallichii 3-5 parts, root tuber of aromatic turmeric 3-5 parts, root of herbaceous peony 3-5 parts, fritillaria thunbergii 3-5 parts, pangolin 3-5 parts, prolong recklessly Rope 0-5 parts, red sage root 0-5 parts, safflower 0-5 parts, selfheal 0-5 parts, Fructus meliae toosendan 0-5 parts, Moschus 0-0.012 parts.
2. newborn addiction dispersing paste according to claim 1, it is characterised in that:The weight portion of each raw material in the Chinese medicine composition For:Radix bupleuri 3-5 parts, frankincense 3-5 parts, myrrh 3-5 parts, Ligusticum wallichii 3-5 parts, root tuber of aromatic turmeric 3-5 parts, root of herbaceous peony 3-5 parts, fritillaria thunbergii 3-5 parts, wear Naze 3-5 parts, corydalis tuber 3-5 parts, red sage root 3-5 parts, safflower 3-5 parts, selfheal 3-5 parts, Fructus meliae toosendan 3-5 parts, 0.01 part of Moschus.
3. newborn addiction dispersing paste according to claim 1 and 2, it is characterised in that:The weight of each raw material in the Chinese medicine composition Measuring part is:Radix bupleuri 3.5-4.5 parts, frankincense 3.5-4.5 parts, myrrh 3.5-4.5 parts, Ligusticum wallichii 3.5-4.5 parts, root tuber of aromatic turmeric 3.5-4.5 parts, Root of herbaceous peony 3.5-4.5 parts, fritillaria thunbergii 3.5-4.5 parts, pangolin 3.5-4.5 parts, corydalis tuber 3.5-4.5 parts, red sage root 3.5-4.5 parts, Safflower 3.5-4.5 parts, selfheal 3.5-4.5 parts, Fructus meliae toosendan 3.5-4.5 parts, 0.01 part of Moschus.
4. newborn addiction dispersing paste according to claim 3, it is characterised in that:The weight portion of each raw material in the Chinese medicine composition For:The weight portion of each raw material is in the Chinese medicine composition:4 parts of radix bupleuri, 4 parts of frankincense, 4 parts of myrrh, 4 parts of Ligusticum wallichii, 4 parts of root tuber of aromatic turmeric, 4 parts of the root of herbaceous peony, 4 parts of fritillaria thunbergii, 4 parts of pangolin, 4 parts of corydalis tuber, 4 parts of the red sage root, 4 parts of safflower, 4 parts of selfheal, 4 parts of Fructus meliae toosendan, musk deer It is fragrant 0.01 part.
5. newborn addiction dispersing paste according to claim 4, it is characterised in that:The weight of the plaster substrate and Chinese medicine composition Than being 4:1.
6. newborn addiction dispersing paste according to claim 5, it is characterised in that:The plaster substrate is black plaster matrix.
7. the newborn addiction dispersing paste according to claim 1-6 any one, it is characterised in that:The red sage root is replaced with pseudo-ginseng.
8. the preparation method of the newborn addiction dispersing paste according to any one in claim 1-7, it is characterised in that:Including following Step:
(1) each raw material is weighed by weight;
(2) red sage root or pseudo-ginseng are ground into powder;
(3) by radix bupleuri, frankincense, myrrh, Ligusticum wallichii, root tuber of aromatic turmeric, the root of herbaceous peony, fritillaria thunbergii, pangolin, corydalis tuber, safflower, selfheal, melia toosendan Son and Moschus are respectively crushed into powder;
(4) each material powder in step (2) and step (3) in addition to Moschus is uniformly mixed;
(5) powder and Moschus that will be mixed in step (4) are well mixed by equal increments method;
(6) plaster substrate is heated to fusing, is then mixed in step (5) is added in the state of plaster substrate is in fusing Powder, and stir, then stop heating, cool down to obtain finished product plaster.
9. the preparation method of newborn addiction dispersing paste according to claim 8, it is characterised in that:The step (2) and step (3) In be that each raw material is respectively crushed into impalpable powder.
10. the preparation method of newborn addiction dispersing paste according to claim 9, it is characterised in that:Plaster base in the step (5) The temperature that matter is in molten state and need to keep is 80 DEG C -82 DEG C.
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Publication number Priority date Publication date Assignee Title
CN109078154A (en) * 2018-10-31 2018-12-25 中山市六安堂健康管理有限公司 A kind of pharmaceutical composition and its preparation method and application for treating the proliferation of mammary gland
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CN111281947A (en) * 2020-04-15 2020-06-16 郭桂芳 Composite medicine for treating mammary nodules
CN111772251A (en) * 2020-08-10 2020-10-16 杜卓航 Functional bra and preparation method thereof

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