CN1044091C - Chinese-medicinal capsule for treatment of psoriasis - Google Patents

Chinese-medicinal capsule for treatment of psoriasis Download PDF

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CN1044091C
CN1044091C CN93116527A CN93116527A CN1044091C CN 1044091 C CN1044091 C CN 1044091C CN 93116527 A CN93116527 A CN 93116527A CN 93116527 A CN93116527 A CN 93116527A CN 1044091 C CN1044091 C CN 1044091C
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illness
radix
recovery
whole body
treatment
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CN1099980A (en
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刘岐干
王晋
孔祥海
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刘岐干
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Abstract

The present invention relates to a pure traditional Chinese-medicinal capsule for treating psoriasis. Red sage root, glabrous greenbrier rhizome, dyer woad leaf, purslane, dandelion, unprocessed rehmannia roots, cyrtomium rhizome, spina gleditsiae, cortex moutan, dittany bark, psoralea fruit and parched hawthorn fruit are proportionally mixed with water and are decocted into liquid extract. Ledebouriella root, alkanna tinctoria and natural indigo are added into the liquid extract to be uniformly mixed after being crushed and ground, the mixture is granulated after being atomized and dried, and the granules are capsulated separately in a sterile mode. The present invention has the advantages of little dosage, convenient application, conspicuous treatment effect, low relapse rate, good long-term treatment effect and no toxic or side effect, and particularly, the total effective rate for treating blood-heat type psoriasis can reach 96%.

Description

The psoriatic Chinese medicinal capsule preparation of a kind of treatment
The present invention relates to the psoriatic Chinese medicine preparation of a kind of treatment, particularly a kind of capsule preparations.
Psoriasis is the higher refractory skin of a kind of sickness rate, and modern medicine still fails to illustrate fully to the cause of disease and the pathogeny of primary disease, does not still have specific therapy at present.
Doctor trained in Western medicine is used immunosuppressant class Drug therapy psoriasis, as ethyliminum, bimolane etc., though these medicines have certain alleviation to symptom, obvious toxic and side effects is arranged all, and the relapse rate height, and late result is not ideal enough.
According to theory of Chinese medical science, psoriasis is generally controlled by heat in blood, the dry amphitypy opinion of blood.The first-selected Chinese medicine preparation of using clinically has FUFANG QINGDAI WAN at present, and it is 91% that this medicine is treated psoriatic total effective rate.The Pilulae Indigo Naturalis preparation is the watered pill, and its dosage is big, takes inconvenience.
The purpose of this invention is to provide a kind of psoriatic capsule preparations of preparing for the raw material hybrid process with the Chinese herbal medicine of treatment.This medicine taking convenience, curative effect height, relapse rate are low, safety non-toxic, late result are good.
The object of the present invention is achieved like this: the psoriatic Chinese medicinal capsule preparation of a kind of treatment, and it is that component with following proportioning by weight is the medicament that raw material is made:
Radix Salviae Miltiorrhizae 9~15g Rhizoma Smilacis Glabrae 20~30g Folium Isatidis 10~20g
Indigo Naturalis 3~6g Herba Portulacae 3~9g Herba Taraxaci 10~20g
Radix Rehmanniae 10~15g Rhizoma Osmundae 6~9g Radix Saposhnikoviae 3~6g
Spina Gleditsiae 5~15g Radix Arnebiae (Radix Lithospermi) 6~9g Cortex Moutan 6~9g
Cortex Dictamni 10~20g Fructus Psoraleae 10~15g Fructus Crataegi (parched to brown) 10~30g
Preparation method of the present invention can be divided into two kinds according to production scale: one: Radix Salviae Miltiorrhizae, Rhizoma Smilacis Glabrae, Folium Isatidis, Herba Portulacae, Herba Taraxaci, Radix Rehmanniae, Rhizoma Osmundae, Spina Gleditsiae, Cortex Moutan, Cortex Dictamni, Fructus Psoraleae, Fructus Crataegi (parched to brown) 12 flavor Chinese herbal medicine are mixed in proportion, decocting is made fluid extract, with Radix Saposhnikoviae, pulverized 5 #The Radix Arnebiae (Radix Lithospermi) of sieve ground 5 #The Indigo Naturalis of sieve stirs evenly in the adding fluid extract, through atomization drying, granulation, and aseptic subpackaged capsule.
Its two: Radix Salviae Miltiorrhizae, Rhizoma Smilacis Glabrae, Folium Isatidis, Herba Portulacae, Herba Taraxaci, Radix Rehmanniae, Rhizoma Osmundae, Spina Gleditsiae, Cortex Moutan, Cortex Dictamni, Fructus Psoraleae, Fructus Crataegi (parched to brown) 12 flavor Chinese herbal medicine are mixed in proportion, and decocting is made fluid extract, earlier Indigo Naturalis is crossed 5 #Sieve adds in the fluid extract and stirs evenly, and concentrates through water-bath to add Radix Saposhnikoviae successively, pulverized 5 #The Radix Arnebiae (Radix Lithospermi) of sieve stirs evenly makes extractum, then at the oven drying at low temperature below 70 °, pulverizing, aseptic subpackaged capsule.
More than 12 flavor Chinese herbal medicine described in two kinds of preparation methoies need to soak 60 minutes earlier, decoct through four times then, each 50 minutes, with fry in shallow oil for four times medicinal liquid be condensed into fluid extract after mixing, again with other Chinese medicine preparation.
Compatibility of the present invention has adopted Rhizoma Smilacis Glabrae, Herba Taraxaci, Indigo Naturalis, Rhizoma Osmundae, Herba Portulacae, wherein Rhizoma Smilacis Glabrae, Herba Taraxaci detoxification and promoting urination, and Indigo Naturalis blood cooling and ecchymoses removing, removing dampness are held back skin ulcer, the Herba Portulacae cooling blood for hemostasis, sore is separated in the Rhizoma Osmundae heat clearing away.Above compatibility has been given prominence to the effect combination of they heat-clearing and toxic substances removing, removing heat from blood dampness removing, and modern medicine also proves, above Chinese medicine has multiple bacillus, coccus and fungus and suppresses and killing action.
The present invention adopts Spina Gleditsiae, has the detumescence poison holding function that leaks; Adopt Fructus Psoraleae, have astriction, according to another modern medicine study, for oral administration or external through daylight or irradiation under ultraviolet ray, can make local skin pigment new life, plays the speckle removing effect; Adopt Fructus Crataegi (parched to brown) and Radix Salviae Miltiorrhizae compatibility, go into blood system strengthening the power of its blood circulation promoting and blood stasis dispelling, but Fructus Crataegi relieving dyspepsia also, to help the absorption of medicine.
The present invention carries out clinical treatment observation to 150 routine psoriatics since nineteen ninety, wherein: male's 70 examples, women's 80 examples, minimum 6 years old of year order, maximum 60 years old, the shortest 6 days of the course of disease, the longest 32 years.Treatment total effective rate to the blood-heat type psoriatic reaches 96% by statistics, and cure rate is 70%, follows up a case by regular visits to and does not see recurrence in 3 years.All case all has the photo contrast of medication front and back.The present invention is described below 50 routine patients' treatment situation wherein: (seeing below table).The advantage of this medicine is: dosage is little, and is evident in efficacy, taking convenience, and relapse rate is low, and late result is good, does not have any poison and pays effect.
The psoriatic Chinese medicine preparation of treatment according to the present invention's preparation--the elargol capsule of healing, its optimum formula is;
Radix Salviae Miltiorrhizae 9g Rhizoma Smilacis Glabrae 20g Folium Isatidis 10g Indigo Naturalis 3g
Herba Portulacae 9g Herba Taraxaci 15g Radix Rehmanniae 12g Rhizoma Osmundae 9g
Radix Saposhnikoviae 6g Spina Gleditsiae 6g Radix Arnebiae (Radix Lithospermi) 9g Cortex Moutan 9g
Cortex Dictamni 10g Fructus Psoraleae 10g Fructus Crataegi (parched to brown) 20g
Make " more elargol capsule " according to preparation method of the present invention, every capsules includes and concentrates dry product is 0.5g, is equivalent to crude drug 18g.
The present invention at present treats 500 many cases patients, provides two model cases below in conjunction with embodiment:
Fig. 1 be patient's height * * photo before taking medicine.
Fig. 2 be patient's height * * photo after taking medicine.
Fig. 3 be patient's health * * photo before taking medicine.
Fig. 4 be patient's health * * photo after taking medicine.
Case 1: high * *, woman, 35 years old, Shang Jia valley, Baode County, Shanxi Province village people, peasant.In March, 1981, morbidity was diagnosed as " general psoriasis punctata ", saw the doctor for treatment in many places, equal unsatisfactory curative effect, and the patient is very painful.Begin to take " the more elargol capsule " of the present invention's preparation in April, 1991, take medicine every day three times, obey three at every turn, through three courses of treatment (one month is a course of treatment), skin lesion all disappears, and subjective symptoms disappears.
Case 2: health * *, man, 36 years old, Xinzhou Prefecture, Shanxi Province tungsten filament factory, worker.Suffered from psoriasis in 1980, once at Shanxi Medical College's the 3rd Affiliated Hospital's sleep therapy, total institute of Beijing air force phototherapy, the tripe method is let out with crossing by Concord Hospital, all fails to cure.Begin to take " the more elargol capsule " of the present invention's preparation in January, 1992, take medicine every day three times, obey four at every turn, through four courses of treatment (one month is a course of treatment), skin lesion all disappears, and subjective symptoms disappears.
The present invention treats 50 routine psoriatic's curative effect records
Sequence number Name Age Surname is other Affected part Medical history (year) The treatment date The course of treatment (moon) Effect The address Remarks
1 High * * 35 The woman Trunk 10 91.4 3 Recovery from illness Shang Jiayu township, Baode County, Shanxi Province
2 Health * * 36 The man Whole body 12 92.1 4 Recovery from illness Xinzhou, Shanxi Province tungsten filament factory
3 Pay * * 30 The woman Extremity 4 91.2 3 Recovery from illness The conspicuous Medical Depot of Lishu County, Jilin leaf
4 The week * * 47 The man Whole body 3 91.5 4 Recovery from illness Xinzhou City East St, Shanxi Province
5 Lee * * 28 The man Whole body 11 91.4 4 Recovery from illness The township is sowed in the Jingyue County by the Shanxi Province
6 Health * * 36 The man Extremity 3 91.6 3 Recovery from illness Nan Shang village, township, Shanxi Dai County Heaven
7 Liu * * 12 The man Whole body 10 days 91.6 2 Recovery from illness Xinzhou Power Administration, Shanxi Prov.
8 Open * * 18 The man Whole body 6 91.3 4 Recovery from illness Dong Lei township, Wutai County, Shanxi Province
9 Lu * * 20 The man Head, extremity 5 90.7 3 Recovery from illness Yao Zhuan township, Baode County, Shanxi Province
10 The generation * * 39 The man Whole body 19 89.2 4 Recovery from illness Cement plant, Baode County, Shanxi Province
11 Recklessly * * 12 The woman Whole body 11 days 91.9 45 days Recovery from illness Xinzhou Prefecture, Shanxi Province hospital
12 Old * * 12 The man Whole body 3 91.7 2 Recovery from illness Xinzhou, Shanxi Province medical material company
13 Temperature * * 27 The man Head, extremity 8 91.3 3 Recovery from illness Xinzhou, Shanxi Province Building Materials Factory
14 The king * * 15 The man Whole body 4 91.3 3 Recovery from illness Shanxi Province Dai County Ma Fang township
15 Fourth * * 15 The woman Whole body JIUYUE 91.9 67 days Recovery from illness The Shanxi Province makes the county prosperous
16 Liu * * 34 The man Extremity April 91.3 42 days Recovery from illness Xinzhou Prefecture, Shanxi Province procuratorate
17 Open * * 38 The woman Whole body 22 91.8 4 Recovery from illness Secret office of Xinzhou, Shanxi Province prefectural Party committee
18 Lee * * 34 The woman Whole body 3 91.9 92 days Recovery from illness Xinzhou City west Zhang Xiang
19 Zhao * * 34 The woman Whole body 4 91.9 2 Recovery from illness Xinzhou City is broadcast bright town
20 Korea Spro * * 31 The woman Whole body 10 91.8 39 days Recovery from illness Xinzhou City textile mills
Sequence number Name Age Surname is other Affected part Medical history (year) The treatment date The course of treatment (moon) Effect The address Remarks
21 Lu * * 22 The woman Whole body January 91.9 2 Recovery from illness Yuanping City, Shanxi Province chemical fertilizer factory
22 Sieve * * 30 The woman Whole body 10 91.9 32 days Recovery from illness Five Bai Jiazhuan in Shanxi Province
23 Cui * * 33 The man Whole body 11 92.3 2 Recovery from illness Yao Wa township, Baode County, Shanxi Province
24 The king * * 37 The woman Whole body 3 91.4 3 Recovery from illness Shanxi Province Dai County Yang Bao town
25 The king * * 38 The woman Extremity 20 91.8 2 Recovery from illness Xinzhou Prefecture sports school
26 Open * * 55 The man Whole body 32 92.9 4 Recovery from illness Xinzhou tungsten filament factory
27 Open * * 16 The man Whole body 1 93.2 3 Recovery from illness System factory is given in the Xinzhou
28 The bandit * * 36 The woman Whole body 14 93.3 3 Recovery from illness Xinzhou road July 1st grain shop
29 Song * * 7 The woman The trunk extremity 1 93.4 54 days Recovery from illness The Xinzhou Armed Police detachment
30 Pan * * 30 The woman Head, extremity 1 93.7 2 Recovery from illness The department store July 1st, Xinzhou
31 The merchant * * 12 The man The trunk extremity April 93.2 3 Recovery from illness Shanxi agricultural bank
32 Xing * * 26 The woman Whole body February 93.3 3 Recovery from illness Government's bank township, Dingxiang, Shanxi Province
33 Guo * * 42 The man Whole body 15 91.3 3 Recovery from illness Xinzhou tungsten filament factory
34 Beam * * 12 The woman Whole body 20 days 93.4 2 Recovery from illness The Fanzhi, Shanxi county public security bureau
35 The king * * 24 The man Head, extremity 3 93.5 2 Recovery from illness Pianguan County, Shanxi chemical fertilizer factory
36 Old * * 30 The man Whole body July 93.5 3 Recovery from illness Yuanping City, Shanxi levies expense institute
37 The merchant * * 29 The woman Whole body 16 92.7 4 Recovery from illness The Hebei Zhangjiakou City
3 8 Lee * * 60 The woman Head, extremity 1 93.5 2 Recovery from illness Dingxiang County, Shanxi Hu Cun
39 Grandson * * 44 The woman Whole body 30 93.5 3 Recovery from illness Xinzhou, Shanxi Jin Shanpu
40 Open * * 6 The woman Whole body 1 93.6 2 Recovery from illness Mt village, Dingxiang, Shanxi
Sequence number Name Age Surname is other Affected part Medical history (year) The treatment date The course of treatment (moon) Effect The address Remarks
41 Horse * * 25 The man Extremity 4 93.4 3 Recovery from illness Haikou City office in Xin
42 Zhao * * 23 The man Whole body February 93.4 2 Recovery from illness Clay fertilizer station, Xinzhou Prefecture
43 The Ji * * 32 The woman Head, trunk 1 93.3 2 Recovery from illness Yuanping City, Shanxi Highway Regulating Point
44 Beam * * 29 The man Whole body 1 92.8 2 Recovery from illness Yangquan City chemical fertilizer factory
45 Liu * * 11 The woman Whole body 1 90.7 2 Recovery from illness The town is closed at the Fanzhi, Shanxi county town
46 Du * * 37 The man Whole body January 90.7 1 Recovery from illness Rectify No. 2, Chen Jia lane, village, Xinzhou
47 Liu * * 22 The man Whole body 1 91.1 3 Recovery from illness Baode County, Shanxi woods hides the valley township
48 The Ji * * 12 The woman Whole body 6 days 91.7 3 Recovery from illness Xinzhou City South St Cao Shi lane
49 Lee * * 21 The man The extremity trunk 6 91.9 45 days Recovery from illness Sub-level ground is pacified in Quan Zhuan township, Jingle, Shanxi
50 Peace * * 53 The man Whole body 20 90.7 4 Recovery from illness Province builds five companies
Annotate: 1, the above-mentioned the 12nd routine patient FUFANG QINGDAI WAN once for oral administration, KEYIN PIAN DeGrain.
2, the above-mentioned the 36th routine patient FUFANG QINGDAI WAN once for oral administration 5 months is invalid.
3, be one month an above-mentioned course of treatment.

Claims (2)

1, the psoriatic Chinese medicinal capsule preparation of a kind of treatment is characterized in that it is that component with following proportioning by weight is the medicament that raw material is made:
Radix Salviae Miltiorrhizae 9~15g Rhizoma Smilacis Glabrae 20~30g Folium Isatidis 10~20g
Indigo Naturalis 3~6g Herba Portulacae 3~9g Herba Taraxaci 10~20g
Radix Rehmanniae 10~15g Rhizoma Osmundae 6~9g Radix Saposhnikoviae 3~6g
Spina Gleditsiae 5~15g Radix Arnebiae (Radix Lithospermi) 6~9g Cortex Moutan 6~9g
Cortex Dictamni 10~20g Fructus Psoraleae 10~15g Fructus Crataegi (parched to brown) 10~30g
2, the psoriatic Chinese medicinal capsule preparation of a kind of treatment according to claim 1 is characterized in that it is that component with following proportioning by weight is the medicament that raw material is made:
Radix Salviae Miltiorrhizae 9g Rhizoma Smilacis Glabrae 20g Folium Isatidis 10g Indigo Naturalis 3g
Herba Portulacae 9g Herba Taraxaci 15g Radix Rehmanniae 12g Rhizoma Osmundae 9g
Radix Saposhnikoviae 6g Spina Gleditsiae 6g Radix Arnebiae (Radix Lithospermi) 9g Cortex Moutan 9g
Cortex Dictamni 10g Fructus Psoraleae 10g Fructus Crataegi (parched to brown) 20g
CN93116527A 1993-09-07 1993-09-07 Chinese-medicinal capsule for treatment of psoriasis Expired - Fee Related CN1044091C (en)

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Application Number Priority Date Filing Date Title
CN93116527A CN1044091C (en) 1993-09-07 1993-09-07 Chinese-medicinal capsule for treatment of psoriasis

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Application Number Priority Date Filing Date Title
CN93116527A CN1044091C (en) 1993-09-07 1993-09-07 Chinese-medicinal capsule for treatment of psoriasis

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CN1099980A CN1099980A (en) 1995-03-15
CN1044091C true CN1044091C (en) 1999-07-14

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100409881C (en) * 2005-02-24 2008-08-13 赵铁阳 Multi function herbal medicine powder for treating psoriasis

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1053580C (en) * 1996-04-05 2000-06-21 李国雄 Yuxianwan pill for curing psoriasis
CN1056531C (en) * 1997-08-29 2000-09-20 刘进成 Chinese medicinal herb composition for treating skin disease
CN1090485C (en) * 2000-04-15 2002-09-11 兰福明 Psoriasis resisting capsule and its preparation
CN100337646C (en) * 2003-11-26 2007-09-19 许力法 Chinese traditional medicine for treating psoriasis and cutaneous pruritus
CN100350930C (en) * 2005-11-22 2007-11-28 张�浩 External-application Chinese medicine for treating psoriasis
CN100478012C (en) * 2006-01-16 2009-04-15 陕西天宁制药有限责任公司 Chinese medicine for treating pityriasis roasea, psoriasis and drug eruption
CN103041241B (en) * 2012-12-31 2014-04-02 刘爱玲 Compound psoriasis arthropathica removal decoction

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
《中医杂志》1983年24卷12期 1983.12.31 吴风岐 中药治疗牛皮癣50例 *
《辽宁中医杂志》1984年8卷6期 1984.6.30 徐宜厚等中药治疗银 病63例临床分析 *
《辽宁中医杂志》1984年8卷6期 1984.6.30 徐宜厚等中药治疗银 病63例临床分析;《中医杂志》1983年24卷12期 1983.12.31 吴风岐 中药治疗牛皮癣50例 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100409881C (en) * 2005-02-24 2008-08-13 赵铁阳 Multi function herbal medicine powder for treating psoriasis

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