CN106924671B - Mammary nodule eliminating ointment and preparation method thereof - Google Patents
Mammary nodule eliminating ointment and preparation method thereof Download PDFInfo
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- A61K36/185—Magnoliopsida (dicotyledons)
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Abstract
The invention relates to a lump in breast and lump in dissipating paste and its preparation method, it is made up of plaster substrate and Chinese medicinal composition, the weight ratio of said plaster substrate and Chinese medicinal composition is 8: 1.5-2.5; the traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 3-5 parts of radix bupleuri, 3-5 parts of frankincense, 3-5 parts of myrrh, 3-5 parts of ligusticum wallichii, 3-5 parts of radix curcumae, 3-5 parts of radix paeoniae alba, 3-5 parts of thunberg fritillary bulb, 3-5 parts of pangolin, 0-5 parts of rhizoma corydalis, 0-5 parts of salvia miltiorrhiza, 0-5 parts of safflower carthamus, 0-5 parts of selfheal, 0-5 parts of szechwan chinaberry fruit and 0-0.012 parts of musk. The plaster has simple components and obvious drug effect, can treat various breast nodules, can directly send the active ingredients of the plaster into breast tissues through skin pores, can be completely absorbed, has no irritation on a substrate, and has strong acceptability to patients.
Description
Technical Field
The invention relates to a traditional Chinese medicine plaster, in particular to a mammary nodule removing plaster and a preparation method thereof.
Background
The breast nodules are common female gynopathy, namely hyperplasia of mammary glands, are non-tumor and non-inflammatory diseases and are common to women in childbearing age. The breast nodules mainly have 4 types, 1, and the mastodynia (premenstrual pain, menstrual pain, no lump and disappearance after menstruation in adolescence); 2. mammary lobular hyperplasia (20-35 years old, premenstrual pain, multiple nodules with wandering, post-menstrual remissions); 3. fibroadenomas or papillomas (single-shot mass, clear border, large mobility, no pain, adhesions); 4. cystic hyperplasia of breast or sclerosing mastopathy (multiple nodules, flakiness, tough and unclear boundaries, usually bilateral, light tenderness and pain, and the menstrual cycle
And off. The symptoms of breast nodules are mainly manifested by breast distending pain and breast lumps: 1. breast distending pain: the pain is usually unilateral or bilateral breast distending pain or tenderness, the general course of the disease is 2 months to several years, and most patients have the characteristic of periodic pain; 2. breast lumps: lumps are often multiple, unilateral or bilateral, with multiple manifestations in the upper quadrant; and the size and the texture of the powder also change periodically with the menstruation, the mass before the menstruation is enlarged, the texture is harder, the mass after the menstruation is reduced, and the powder is tough but not hard. When palpating, the lump is in node structure, different in size, unclear with the surrounding tissues, mostly tender, non-adhesive with the skin and deep tissues, and can be pushed without swelling of axillary lymph nodes. In addition, the symptoms of breast nodules are manifested as long-term and slow progression, and sometimes as nipple discharge.
To date, over 90 Chinese medicinal treatment formulations for breast nodules have been published. For example, CN200310105406.8 discloses an external plaster for treating mammary gland hyperplasia, mammary gland lobular hyperplasia and cystic hyperplasia of breast, which is prepared from colla cornus cervi, rhizoma curculiginis, radix morindae officinalis, radix linderae, fructus trichosanthis, nidus vespae, fructus forsythiae, centipede, camphor, radix et rhizoma Rhei, benzoin, edible tulip, lignum Aquilariae Resinatum, caulis Aristolochiae Manshuriensis, semen brassicae, musk and the like. CN200810137512.7 discloses a plaster for treating hyperplasia of mammary glands and a preparation method thereof, which is prepared from corydalis tuber 12, turtle shell 8, ground beetle 10, pangolin 8, oyster 8, leech 8, earthworm 10, cassia twig 2, peony 2, rehmannia root 2, cortex moutan 2, peach kernel 2, rhubarb 4, common burreed rhizome 2, zedoary 2, seaweed 2, kelp 2, selfheal 2, myrrh 2, dragon's blood resin 2, frankincense 2, amber 4 and borneol 2 parts; most of the traditional Chinese medicine formulas have complex components; due to the barrier effect of the dermal tissue, the traditional Chinese medicine components in the formula are difficult to permeate into affected parts through the surface layer of the breast to repair blocked and necrotic cells, so that hyperplastic lumps are softened and dispersed, the hyperplastic lumps cannot be directly sent into mammary tissue through skin pores, and the effective components cannot be completely absorbed and are poor in absorption; in addition, the matrix is also highly irritating and is likely to cause skin redness, swelling, ulceration, etc., if it is not used carefully.
Disclosure of Invention
The invention aims to provide a breast nodule removing plaster and a preparation method thereof, the plaster has simple components and obvious drug effect, can treat various breast nodules, can directly send the active ingredients of the plaster into breast tissues through pores of skin, can completely absorb the active ingredients, has no irritation on a substrate, and has strong acceptability to patients.
The purpose of the invention is realized by the following technical scheme:
a lump in breast dissipating plaster comprises plaster matrix and Chinese medicinal composition, wherein the weight ratio of the plaster matrix to the Chinese medicinal composition is 8: 1.5-2.5; the traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 3-5 parts of radix bupleuri, 3-5 parts of frankincense, 3-5 parts of myrrh, 3-5 parts of ligusticum wallichii, 3-5 parts of radix curcumae, 3-5 parts of radix paeoniae alba, 3-5 parts of thunberg fritillary bulb, 3-5 parts of pangolin, 0-5 parts of rhizoma corydalis, 0-5 parts of salvia miltiorrhiza, 0-5 parts of safflower carthamus, 0-5 parts of selfheal, 0-5 parts of szechwan chinaberry fruit and 0-0.012 parts of musk.
Further, the traditional Chinese medicine composition comprises the following raw materials in parts by weight: 3-5 parts of radix bupleuri, 3-5 parts of frankincense, 3-5 parts of myrrh, 3-5 parts of ligusticum wallichii, 3-5 parts of radix curcumae, 3-5 parts of radix paeoniae alba, 3-5 parts of thunberg fritillary bulb, 3-5 parts of pangolin, 3-5 parts of rhizoma corydalis, 3-5 parts of salvia miltiorrhiza, 3-5 parts of safflower, 3-5 parts of selfheal, 3-5 parts of szechwan chinaberry fruit and 0.01 part of musk.
Further, the traditional Chinese medicine composition comprises the following raw materials in parts by weight: 3.5 to 4.5 parts of bupleurum, 3.5 to 4.5 parts of frankincense, 3.5 to 4.5 parts of myrrh, 3.5 to 4.5 parts of szechuan lovage rhizome, 3.5 to 4.5 parts of turmeric root-tuber, 3.5 to 4.5 parts of white paeony root, 3.5 to 4.5 parts of thunberg fritillary bulb, 3.5 to 4.5 parts of pangolin, 3.5 to 4.5 parts of corydalis tuber, 3.5 to 4.5 parts of salvia miltiorrhiza, 3.5 to 4.5 parts of safflower, 3.5 to 4.5 parts of selfheal, 3.5 to 4.54.5 parts of szechwan chinaberry fruit and 0.01 part of musk.
Further, the traditional Chinese medicine composition comprises the following raw materials in parts by weight 4.5: the traditional Chinese medicine composition comprises the following raw materials in parts by weight: 4 parts of radix bupleuri, 4 parts of frankincense, 4 parts of myrrh, 3.5 parts of ligusticum wallichii, 4 parts of radix curcumae, 4 parts of radix paeoniae alba, 4 parts of thunberg fritillary bulb, 4 parts of pangolin, 4 parts of rhizoma corydalis, 4 parts of red lead, 4 parts of ginseng, 4 parts of safflower carthamus, 4 parts of selfheal, 4 parts of szechwan chinaberry fruit and 0.01 part of musk.
Further, the weight ratio of the plaster matrix to the traditional Chinese medicine composition is 4: 1.
Furthermore, the plaster matrix is a black plaster matrix.
Further, radix notoginseng is used for replacing the salvia miltiorrhiza.
The preparation method of the nodules of breast and mass dissipating paste comprises the following steps:
(1) weighing the raw materials in parts by weight;
(2) pulverizing Saviae Miltiorrhizae radix or Notoginseng radix into powder;
(3) pulverizing bupleuri radix, Olibanum, Myrrha, rhizoma Ligustici Chuanxiong, radix Curcumae, radix Paeoniae alba, Bulbus Fritillariae Thunbergii, squama Manis, rhizoma corydalis, Carthami flos, Prunellae Spica, fructus Toosendan and Moschus into powder respectively;
(4) stirring and mixing the raw material powder except the musk in the step (2) and the step (3) uniformly;
(5) uniformly mixing the uniformly mixed powder in the step (4) and musk according to an equivalent incremental method;
(6) and (3) heating the plaster matrix to be molten, adding the uniformly mixed powder in the step (5) under the condition that the plaster matrix is molten, uniformly stirring, stopping heating, and cooling to obtain the finished plaster.
Furthermore, in the step (2) and the step (3), the raw materials are respectively crushed into superfine powder.
Further, the plaster matrix in the step (5) needs to be kept at a temperature of 80-82 ℃ in a molten state.
The action principle of the breast nodule removing paste of the invention is as follows:
the breast nodule removing paste consists of radix bupleuri, frankincense, myrrh, ligusticum wallichii, radix curcumae, radix paeoniae alba, thunberg fritillary bulb, pangolin, rhizoma corydalis, salvia miltiorrhiza (or pseudo-ginseng), safflower, selfheal, szechwan chinaberry fruit and musk; wherein, bupleurum, frankincense, myrrh, hemlock parsley, turmeric root-tuber, white paeony root, thunberg fritillary bulb and pangolin as essential components; corydalis tuber, red sage root (or notoginseng), safflower, selfheal, toosendan fruit and musk are non-essential components. The radix bupleuri is a monarch drug for soothing liver-qi stagnation, and the rhizoma ligustici wallichii and the radix curcumae are ministerial drugs for activating blood and relieving pain and promoting qi; white peony root, radix paeoniae alba nourishes blood and soothes liver, so that liver qi can be regulated, and qi can be removed; bulbus Fritillariae Thunbergii and squama Manis have effects of promoting blood circulation, dredging collaterals, and resolving hard mass; frankincense and myrrh have the functions of activating blood and relieving pain and relieving swelling; corydalis tuber, salvia miltiorrhiza (or pseudo-ginseng), safflower, szechwan chinaberry fruit and musk are used for strengthening the functions of activating blood and dissolving stasis, and selfheal is used for clearing heat and purging fire, and eliminating stagnation and reducing swelling; the medicines are used together to play the effects of dispersing stagnated liver qi, relieving depression, eliminating swelling, resolving hard mass, promoting blood circulation and relieving pain.
The invention has the beneficial effects that:
(1) the breast nodule removing paste has the effects of soothing liver-qi stagnation, relieving swelling, removing stasis, activating blood and relieving pain. Clinical verification shows that the plaster has the effective rate of 93 percent and the cure rate of 80 percent for treating various breast nodules, has simple formula and obvious drug effect.
(2) The Chinese medicinal components in the formula of the breast nodule-removing plaster can permeate into affected parts through the surface layer of breasts to repair blocked and necrotic cells, so that hyperplasia masses are softened and dispersed, the effective components of the plaster are directly delivered into mammary tissue through skin pores, and the effective components can be completely absorbed.
(3) The lump in breast dissipating plaster adopts the black plaster substrate, the black plaster substrate has no irritation, and the acceptability of patients is strong.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the technical solutions of the present invention will be described in detail below. It is to be understood that the described embodiments are merely exemplary of the invention, and not restrictive of the full scope of the invention. All other embodiments, which can be derived by a person skilled in the art from the examples given herein without any inventive step, are within the scope of the present invention.
First, preparation example:
preparation example 1:
1.1 formula: a lump in breast dissipating plaster consists of a black plaster matrix and a traditional Chinese medicine composition, wherein the weight ratio of the black plaster matrix to the traditional Chinese medicine composition is 4: 1. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 4 parts of radix bupleuri, 4 parts of frankincense, 4 parts of myrrh, 4 parts of ligusticum wallichii, 4 parts of radix curcumae, 4 parts of radix paeoniae alba, 4 parts of thunberg fritillary bulb, 4 parts of pangolin, 4 parts of corydalis tuber, 4 parts of salvia miltiorrhiza, 4 parts of safflower, 4 parts of selfheal, 4 parts of szechwan chinaberry fruit and 0.01 part of musk; 208.04 parts of black plaster matrix.
1Kg of the plaster of the present invention is prepared by the following raw materials: 15.38g of radix bupleuri, 15.38g of frankincense, 15.38g of myrrh, 15.38g of ligusticum wallichii, 15.38g of radix curcumae, 15.38g of radix paeoniae alba, 15.38g of thunberg fritillary bulb, 15.38g of pangolin, 15.38g of rhizoma corydalis, 15.38g of salvia miltiorrhiza, 15.38g of safflower carthamus, 15.38g of selfheal, 15.38g of szechwan chinaberry fruit and 0.04g of musk; the black plaster matrix is 800 g.
1.2 preparation method, comprising the following steps:
(1) weighing the raw materials according to the weight;
(2) respectively pulverizing Saviae Miltiorrhizae radix, bupleuri radix, Olibanum, Myrrha, rhizoma Ligustici Chuanxiong, radix Curcumae, radix Paeoniae alba, Bulbus Fritillariae Thunbergii, squama Manis, rhizoma corydalis, Carthami flos, Prunellae Spica, fructus Toosendan and Moschus into fine powder;
(3) stirring and mixing the raw material powder except the musk in the step (2) uniformly;
(4) uniformly mixing the uniformly mixed powder in the step (3) and musk according to an equivalent incremental method;
(5) and (3) heating the black plaster matrix to 80-82 ℃, adding the uniformly mixed powder in the step (4) when the black plaster matrix is molten after the black plaster matrix is molten, uniformly stirring, stopping heating, and cooling to obtain the finished plaster.
Preparation example 2:
2.1 formula: a lump in breast dissipating plaster consists of a black plaster matrix and a traditional Chinese medicine composition, wherein the weight ratio of the black plaster matrix to the traditional Chinese medicine composition is 8: 1.5. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 3 parts of radix bupleuri, 5 parts of frankincense, 5 parts of myrrh, 3 parts of ligusticum wallichii, 3 parts of radix curcumae, 3 parts of radix paeoniae alba, 5 parts of thunberg fritillary bulb and 3 parts of pangolin; 160 parts of black plaster matrix.
1Kg of the plaster of the present invention is prepared by the following raw materials: 15.79g of radix bupleuri, 26.32g of frankincense, 26.32g of myrrh, 15.79g of ligusticum wallichii, 15.79g of radix curcumae, 15.79g of radix paeoniae alba, 26.32g of thunberg fritillary bulb and 15.79g of pangolin; the black plaster matrix is 842.11 g.
2.2 preparation method, comprising the following steps:
(1) weighing the raw materials according to the weight;
(2) pulverizing bupleuri radix, Olibanum, Myrrha, rhizoma Ligustici Chuanxiong, radix Curcumae, radix Paeoniae alba, Bulbus Fritillariae Thunbergii and squama Manis into fine powder respectively;
(3) stirring and mixing the raw material powder except the musk in the step (2) uniformly;
(4) and (3) heating the black plaster matrix to 80-82 ℃, adding the uniformly mixed powder in the step (3) when the black plaster matrix is molten after the black plaster matrix is molten, uniformly stirring, stopping heating, and cooling to obtain the finished plaster.
Preparation example 3:
3.1 formula: a lump in breast dissipating plaster consists of a black plaster matrix and a traditional Chinese medicine composition, wherein the weight ratio of the black plaster matrix to the traditional Chinese medicine composition is 4: 1. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 5 parts of radix bupleuri, 3 parts of frankincense, 3 parts of myrrh, 5 parts of ligusticum wallichii, 5 parts of radix curcumae, 5 parts of radix paeoniae alba, 3 parts of thunberg fritillary bulb, 5 parts of pangolin, 3 parts of corydalis tuber, 5 parts of pseudo-ginseng, 3 parts of safflower, 3 parts of selfheal, 5 parts of szechwan chinaberry fruit and 0.01 part of musk; 185.63 parts of black plaster matrix.
1Kg of the plaster of the present invention is prepared by the following raw materials: 20.95g of radix bupleuri, 12.57g of frankincense, 12.57g of myrrh, 20.95g of ligusticum wallichii, 20.95g of radix curcumae, 20.95g of radix paeoniae alba, 12.57g of thunberg fritillary bulb, 20.95g of pangolin, 12.57g of rhizoma corydalis, 20.95g of pseudo-ginseng, 12.57g of safflower, 12.57g of selfheal, 20.95g of szechwan chinaberry fruit and 0.04g of musk; the black plaster matrix is 777.87 g.
3.2 the preparation method comprises the following steps:
(1) weighing the raw materials according to the weight;
(2) respectively pulverizing Notoginseng radix, bupleuri radix, Olibanum, Myrrha, rhizoma Ligustici Chuanxiong, radix Curcumae, radix Paeoniae alba, Bulbus Fritillariae Thunbergii, squama Manis, rhizoma corydalis, Carthami flos, Prunellae Spica, fructus Toosendan and Moschus into fine powder;
(3) stirring and mixing the raw material powder except the musk in the step (2) uniformly;
(4) uniformly mixing the uniformly mixed powder in the step (3) and musk according to an equivalent incremental method;
(5) and (3) heating the black plaster matrix to 80-82 ℃, adding the uniformly mixed powder in the step (4) when the black plaster matrix is molten after the black plaster matrix is molten, uniformly stirring, stopping heating, and cooling to obtain the finished plaster.
Preparation example 4:
4.1 formula: a lump in breast dissipating plaster consists of a black plaster matrix and a traditional Chinese medicine composition, wherein the weight ratio of the black plaster matrix to the traditional Chinese medicine composition is 4: 1. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 3.5 parts of radix bupleuri, 4 parts of frankincense, 4.5 parts of myrrh, 4.5 parts of ligusticum wallichii, 4 parts of radix curcumae, 4 parts of radix paeoniae alba, 3.5 parts of thunberg fritillary bulb, 3.5 parts of pangolin, 4.5 parts of corydalis tuber, 3.5 parts of salvia miltiorrhiza, 4 parts of safflower, 4 parts of selfheal, 3.5 parts of szechwan chinaberry fruit and 0.01 part of musk; 204.04 parts of black plaster matrix.
1Kg of the plaster of the present invention is prepared by the following raw materials: 13.72g of radix bupleuri, 15.68g of frankincense, 17.64g of myrrh, 17.64g of ligusticum wallichii, 15.68g of radix curcumae, 15.68g of radix paeoniae alba, 13.72g of thunberg fritillary bulb, 13.72g of pangolin, 17.64g of rhizoma corydalis, 13.72g of salvia miltiorrhiza, 15.68g of safflower, 15.68g of selfheal, 13.72g of szechwan chinaberry fruit and 0.04g of musk; the black plaster matrix is 800 g.
4.2 the preparation method comprises the following steps:
(1) weighing the raw materials according to the weight;
(2) respectively pulverizing Saviae Miltiorrhizae radix, bupleuri radix, Olibanum, Myrrha, rhizoma Ligustici Chuanxiong, radix Curcumae, radix Paeoniae alba, Bulbus Fritillariae Thunbergii, squama Manis, rhizoma corydalis, Carthami flos, Prunellae Spica, fructus Toosendan and Moschus into fine powder;
(3) stirring and mixing the raw material powder except the musk in the step (2) uniformly;
(4) uniformly mixing the uniformly mixed powder in the step (3) and musk according to an equivalent incremental method;
(5) and (3) heating the black plaster matrix to 80-82 ℃, adding the uniformly mixed powder in the step (4) when the black plaster matrix is molten after the black plaster matrix is molten, uniformly stirring, stopping heating, and cooling to obtain the finished plaster.
Preparation example 5:
5.1 formula: a lump in breast dissipating plaster consists of a black plaster matrix and a traditional Chinese medicine composition, wherein the weight ratio of the black plaster matrix to the traditional Chinese medicine composition is 4: 1. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 3.5 parts of radix bupleuri, 4.5 parts of frankincense, 3 parts of myrrh, 5 parts of ligusticum wallichii, 5 parts of radix curcumae, 3 parts of radix paeoniae alba, 4.5 parts of thunberg fritillary bulb, 4 parts of pangolin, 3 parts of pseudo-ginseng, 3.5 parts of safflower, 4 parts of selfheal and 0.01 part of musk; 172.04 parts of black plaster matrix.
1Kg of the plaster of the present invention is prepared by the following raw materials: 16.28g of radix bupleuri, 20.93g of frankincense, 13.95g of myrrh, 23.25g of ligusticum wallichii, 23.25g of radix curcumae, 13.95g of radix paeoniae alba, 20.93g of thunberg fritillary bulb, 18.60g of pangolin, 13.95g of pseudo-ginseng, 16.28g of safflower, 18.60g of selfheal and 0.05g of musk; the black plaster matrix is 800 g.
5.2 the preparation method comprises the following steps:
(1) weighing the raw materials according to the weight;
(2) respectively pulverizing Notoginseng radix, bupleuri radix, Olibanum, Myrrha, rhizoma Ligustici Chuanxiong, radix Curcumae, radix Paeoniae alba, Bulbus Fritillariae Thunbergii, squama Manis, Carthami flos, Prunellae Spica and Moschus into fine powder;
(3) stirring and mixing the raw material powder except the musk in the step (2) uniformly;
(4) uniformly mixing the uniformly mixed powder in the step (3) and musk according to an equivalent incremental method;
(5) and (3) heating the black plaster matrix to 80-82 ℃, adding the uniformly mixed powder in the step (4) when the black plaster matrix is molten after the black plaster matrix is molten, uniformly stirring, stopping heating, and cooling to obtain the finished plaster.
Second, test example:
1. and (3) clinical trials:
1) general data: clinical observations were made for 500 various breast nodule cases with the ages of 24 years minimum and 65 years maximum.
2) The treatment method comprises the following steps: the plaster prepared in preparation example 1 of the present invention was applied to the affected part 1 time per person, one patch at a time.
3) The evaluation standard of curative effect is as follows:
and (3) curing: clinical symptoms disappear completely, pain and discomfort disappear completely, and normal life is restored.
The method has the following advantages: all or major symptoms are eliminated significantly, pain and discomfort are eliminated significantly, but mild symptoms appear, and normal life is only partially restored.
And (4) invalidation: no obvious change in symptoms and signs.
4) The treatment results are as follows: the treatment results are shown in table 1:
TABLE 1
| Total number of cases | Cure of disease | Is effective | Invalidation | High efficiency |
| 500 | 400 | 65 | 35 | 93％ |
5) Typical clinical cases are:
① Zhang, female, 50 years old, and the onset of 2000 mammary nodule, the disease lasts for 16 years, and the symptoms disappear after 60 days of using the medicine.
②, Wei-Chi, female, age 45, and onset of 2010, mammary nodules, the symptoms last 6 years, and the symptoms disappear after 50 days of the medicine.
The clinical tests show that the plaster prepared in the preparation example 1 has the effective rate of 93% and the cure rate of 80% for treating the breast nodules. Of course, the plasters prepared in preparation examples 2 to 5 of the present invention were used to treat breast nodules with the same therapeutic effects as those of preparation example 1.
The above description is only for the specific embodiments of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art can easily conceive of the changes or substitutions within the technical scope of the present invention, and all the changes or substitutions should be covered within the scope of the present invention. Therefore, the protection scope of the present invention shall be subject to the protection scope of the appended claims.
Claims (4)
1. The breast nodule eliminating ointment is characterized in that: the plaster comprises a plaster matrix and a traditional Chinese medicine composition, wherein the weight ratio of the plaster matrix to the traditional Chinese medicine composition is 4: 1; the traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 4 parts of radix bupleuri, 4 parts of frankincense, 4 parts of myrrh, 4 parts of ligusticum wallichii, 4 parts of radix curcumae, 4 parts of radix paeoniae alba, 4 parts of thunberg fritillary bulb, 4 parts of pangolin, 4 parts of corydalis tuber, 4 parts of salvia miltiorrhiza, 4 parts of safflower, 4 parts of selfheal, 4 parts of szechwan chinaberry fruit and 0.01 part of musk;
the plaster matrix is black plaster matrix.
2. The method for preparing nodules of breast of claim 1, wherein: the method comprises the following steps:
(1) weighing the raw materials in parts by weight;
(2) pulverizing Saviae Miltiorrhizae radix into powder;
(3) pulverizing bupleuri radix, Olibanum, Myrrha, rhizoma Ligustici Chuanxiong, radix Curcumae, radix Paeoniae alba, Bulbus Fritillariae Thunbergii, squama Manis, rhizoma corydalis, Carthami flos, Prunellae Spica, fructus Toosendan and Moschus into powder respectively;
(4) stirring and mixing the raw material powder except the musk in the step (2) and the step (3) uniformly;
(5) uniformly mixing the uniformly mixed powder in the step (4) and musk according to an equivalent incremental method;
(6) and (3) heating the plaster matrix to be molten, adding the uniformly mixed powder in the step (5) under the condition that the plaster matrix is molten, uniformly stirring, stopping heating, and cooling to obtain the finished plaster.
3. The method for preparing nodules of breast of claim 2, wherein: in the step (2) and the step (3), the raw materials are respectively crushed into superfine powder.
4. The method for preparing nodules of breast of claim 3, wherein: in the step (5), the temperature of the plaster matrix which is in a melting state needs to be kept at 80-82 ℃.
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| CN109620922A (en) * | 2019-01-28 | 2019-04-16 | 浴康中医保健养生（江苏）有限公司 | It is a kind of for treating the Chinese materia medica preparation and preparation method thereof of tubercle calcification |
| CN111281947A (en) * | 2020-04-15 | 2020-06-16 | 郭桂芳 | Composite medicine for treating mammary nodules |
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| CN102178896A (en) * | 2011-04-28 | 2011-09-14 | 时红霞 | Traditional Chinese medicine composition for treating breast hyperplasia and preparation method of composition |
| CN105213960A (en) * | 2014-06-30 | 2016-01-06 | 黄钰 | For controlling the Chinese powder medicine of cyclomastopathy |
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| CN102178896A (en) * | 2011-04-28 | 2011-09-14 | 时红霞 | Traditional Chinese medicine composition for treating breast hyperplasia and preparation method of composition |
| CN105213960A (en) * | 2014-06-30 | 2016-01-06 | 黄钰 | For controlling the Chinese powder medicine of cyclomastopathy |
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