CN106900981A - It is a kind of to be applied to the immunopotentiating composition containing micro-powder of Chinese herbs, xylo-oligosaccharide, enzyme preparation and probiotics in livestock and poultry cultivation - Google Patents
It is a kind of to be applied to the immunopotentiating composition containing micro-powder of Chinese herbs, xylo-oligosaccharide, enzyme preparation and probiotics in livestock and poultry cultivation Download PDFInfo
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- CN106900981A CN106900981A CN201710120808.7A CN201710120808A CN106900981A CN 106900981 A CN106900981 A CN 106900981A CN 201710120808 A CN201710120808 A CN 201710120808A CN 106900981 A CN106900981 A CN 106900981A
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- 238000002360 preparation method Methods 0.000 title claims abstract description 30
- 239000006041 probiotic Substances 0.000 title claims abstract description 28
- 235000018291 probiotics Nutrition 0.000 title claims abstract description 28
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- 239000000203 mixture Substances 0.000 title claims abstract description 25
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- MUPFEKGTMRGPLJ-ZQSKZDJDSA-N raffinose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO[C@@H]2[C@@H]([C@@H](O)[C@@H](O)[C@@H](CO)O2)O)O1 MUPFEKGTMRGPLJ-ZQSKZDJDSA-N 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2400/00—Lactic or propionic acid bacteria
- A23V2400/11—Lactobacillus
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2400/00—Lactic or propionic acid bacteria
- A23V2400/11—Lactobacillus
- A23V2400/113—Acidophilus
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2400/00—Lactic or propionic acid bacteria
- A23V2400/51—Bifidobacterium
Landscapes
- Fodder In General (AREA)
- Feed For Specific Animals (AREA)
Abstract
Present invention offer is a kind of to be applied to the immunopotentiating composition containing micro-powder of Chinese herbs, xylo-oligosaccharide, enzyme preparation and probiotics in livestock and poultry cultivation, and micro-powder of Chinese herbs therein is obtained by Crushing of Ultrafine after mixing (particle size diameter is less than 20 microns) by the Radix Astragali, the fruit of Chinese wolfberry, Radix Angelicae Sinensis, Poria cocos, Psoralea corylifolia, Semen Cuscutae, the taste Chinese herbal medicine of the bighead atractylodes rhizome 7；Enzyme preparation is combined be made according to a certain percentage by cellulase, pectase and β glucose oxidases；The product belongs to the composition of functional oligose, Chinese herbal medicine micro mist, enzyme preparation and probiotics immunopotentiator, additive capacity is the 0.1% of feed relative, the present invention is powder powder preparation, synergy is reached by xylo-oligosaccharide, Chinese herbal medicine micro mist, the scientific compatibility between enzyme preparation and probiotics, the immunocompetence and anti-bacteria and anti-virus ability of livestock and poultry body can not only be effectively improved, and with nontoxic, noresidue, can effectively reduce medicament residue and the features such as pathogenic microorganism is remained.
Description
Technical field
The invention belongs to feed additive field, specifically say and be related to be applied in livestock and poultry cultivation containing micro-powder of Chinese herbs, low
The immunopotentiating composition of xylan, enzyme preparation and probiotics.
Background technology
For a long time, using antibiotic broad-spectrum sterilization the drawbacks of and side effect increasingly manifest with it is obvious to all, what it brought
Microbial environment in not exclusively animal drug resistance and food-safety problem, and heavy damage animal body.Due to
The value volume and range of product of internal beneficial bacterium declines too fast and can not be supplemented accordingly, and livestock and poultry show apocleisis, lassitude, exempt from
Epidemic disease power is low, and hair color is not good to wait sub-health state, finally influences product quality, threatens the economic benefit of culturist.
Micro-powder of Chinese herbs is to implement the pulvis that breaking-wall cell is processed to Chinese medicine using Crushing of Ultrafine technology leading in the world.
80% is based on autonomic drug, to be stored the active ingredient of plant medicinal material in the cell more in Chinese medicine, Crushing of Ultrafine technology (in
Medicine Crushing of Ultrafine technology refers to that more than 3mm material particles are crushed to the mistake that particle diameter is below 30um using machinery or fluid dynamic
Journey) vegetable drug cell membrane can be broken, intracellular active ingredient is fully discharged, so as to improve the biological utilisation of medicinal material
Degree, is conducive to livestock and poultry body to absorb medicine, Chinese herbal medicine clinical therapeutic efficacy is produced qualitative leap.
Xylo-oligosaccharide be with the plant (such as corncob, bagasse, raffinose, wheat bran, birch) rich in xylan be raw material,
By xylanase hydrolysis, a class non-digestible oligosaccharide obtained by separation and purification.This sugar is by 2~7 xylose molecules with β -1,4
Glycosidic bond is combined into, stable in physicochemical property, acidproof, heat-resisting, and has the function of very strong propagation beneficial bacteria of intestinal tract.
Xylo-oligosaccharide can strengthen the immunologic function of body by breeding Bifidobacterium, and its mechanism may be by reducing
Complementary Th (helper lymphocyte T) -2 is reacted and strengthens the non-equilibrium state of Th1 reaction regulations Th1/Th2.For lacking
The infant of breast-feeding, can significantly improve its immunologic function, and prevent and treat due to immunologic function after Bifidobacterium propagation
Disease caused by low.
Xylo-oligosaccharide is applied to the function of feed addictive：
(1) promote the breeding of beneficial bacterium in animal alimentary canal, suppress harmful bacteria growing, improve microorganism species balance；
(2) combination of blocking pathogen and host cell receptor；
(3) immune system of stimulating animal body, enhance immunity；
(4) strengthen animal disease resistant ability, reduce the incidence of disease, improve the prevention effect to Animal diseases；
(5) improve efficiency of feed utilization, improve breeding performonce fo animals；
(6) pollution to environment is reduced, improves the sanitary condition of animal productiong environment；
Enzyme is the large biological molecule material that the class that biological cell plasm synthesizes has high catalytic activity, widely distributed
In in animal, plant and microbial body, very important effect is played in the life process such as body growth development and breeding.Two
The late nineteen eighties in tenth century, foreign countries start to widely use feed enzyme, some feed enzyme product elder generations of the nineties U.S., Finland
Enter Chinese market afterwards, the research of feed enzyme and application since this China, current fodder enzyme preparation is in livestock and poultry breeding industry application
Very universal, culture fishery also has some reports using enzyme preparation.Developing rapidly for aquaculture, has both brought huge
Economic profit, while also generating the severe contamination of breeding water body, indigested nitrogen, phosphorus constitute breeding water body in feed
One of primary pollution source, therefore efficiency of feed utilization is improved, reducing water pollution has turned into aquaculture worker effort from now on
Direction.And enzyme preparation, with feed digestion absorptivity is improved, saves albumen as a kind of novel environment-friendlygreen green feed addictive
Source, it is nontoxic, have no side effect, noresidue and the advantages of have no drug resistance.
Probiotics is the class active microorganism beneficial to host, is colonized in human body intestinal canal, reproductive system, can be produced
Definite health efficacy is so as to the active beneficial microorganism general name for improving host's microecological balance, playing beneficial effect.It is human body, dynamic
Beneficial bacterium or fungi mainly have in object：Clostridium butyricum, Bacillus acidi lactici, Bifidobacterium, lactobacillus acidophilus, saccharomycete etc..
At present the most powerful product of the function studied in the world be mainly all kinds of microorganism groups of the above into composite reactive probiotics, its is wide
It is general to be applied to bioengineering, industrial or agricultural, food security and life and health field.
Probiotics energy metabolism product produces biological antagonist, strengthens body immunity：Probiotics can produce organic acid, free fat
Fat acid, hydrogen peroxide, bacteriocin suppress the growth of other harmful bacterias；Under making aerobic-type pathogenic bacteria significantly by " biology takes oxygen by force "
Drop, probiotics can colonize and biological barrier is formed between surface or cell in mucous membrane, skin etc., and these barriers can prevent cause of disease
Colonizing for microorganism, plays occupy-place, contention nutrition, antagonism.And the non-specific immune function of body can be stimulated, improve
The activity of NKT (NK) cell, strengthens the secretion of intestine immunity globulin IgA, improves the barrier function of enteron aisle.
The content of the invention
Present invention aim at a kind of Immune-enhancing effect containing micro-powder of Chinese herbs, xylo-oligosaccharide, enzyme preparation and probiotics of offer
Application of the composition in livestock and poultry cultivation, can effectively improve the balance of microorganism species in animal body, from micro-powder of Chinese herbs,
Xylo-oligosaccharide, enzyme preparation and probiotic composition.Said composition does not only have weightening growth promoting effect to livestock and poultry, and body is exempted from
Epidemic disease function has facilitation, can improve the ability of body fight bacterium and virus, can effectively reduce animal product medicine is residual and disease
Substance is remained.
Technical scheme is summarized as follows：
1. a kind of immunopotentiating composition containing micro-powder of Chinese herbs, xylo-oligosaccharide, enzyme preparation and probiotics, enzyme preparation collaboration
Probiotic action produces polypeptide and the prebiotic factor in micro-powder of Chinese herbs, fermentation, acts on body, and xylo-oligosaccharide is by probiotics profit
With, enteron aisle pH value is reduced, suppress harmful bacteria growing, probiotics is largely bred in enteron aisle, reach above-mentioned health-care efficacy.It is special
It is each component content in terms of parts by weight to levy：Micro-powder of Chinese herbs：25 parts -35 parts, xylo-oligosaccharide：25 parts -55 parts, enzyme preparation：5
Part -25 parts, probiotics：5 parts -10 parts.
2. the micro-powder of Chinese herbs in above-mentioned composition includes the Radix Astragali, the fruit of Chinese wolfberry, Radix Angelicae Sinensis, Poria cocos, Psoralea corylifolia, Semen Cuscutae, the bighead atractylodes rhizome,
Said herbal medicine is obtained by Crushing of Ultrafine after mixing (particle size diameter is less than 20 microns).The content in terms of parts by weight：The Radix Astragali：16-
21 parts, the fruit of Chinese wolfberry：13-18 parts, Radix Angelicae Sinensis：7-12 parts, Poria cocos：11-16 parts, Psoralea corylifolia：12-16 parts, Semen Cuscutae：14-19 parts, it is white
Art：6-9 parts.
3. enzyme preparation includes cellulase, pectase, three kinds of β-glucose oxidase in above-mentioned composition.With parts by weight
Meter content：Cellulase：15-50 parts, pectase：10-25 parts, β-glucose oxidase：5-30 parts.
4. probiotics includes acidophilus breast clostridium, Bacillus acidi lactici, saccharomycete, four kinds of Bifidobacterium in above-mentioned composition.With weight
Amount number meter content：Acidophilus breast clostridium：15-30 parts, Bacillus acidi lactici：25-35 parts, saccharomycete：5-20 parts, Bifidobacterium：5-20
Part.
5. the present composition is applied to all fowl poultry kind cultivation growth promotions as feed addictive, and adding proportion is
0.05%-0.15%.
Effective result of the invention is：
The present invention reaches collaboration and makees from xylo-oligosaccharide, Chinese herbal medicine micro mist, the scientific compatibility between enzyme preparation and probiotics
With the immunocompetence and anti-bacteria and anti-virus ability of livestock and poultry body can not only be effectively improved, and with nontoxic, noresidue, can be had
The features such as effect reduction medicament residue and pathogenic microorganism are remained.The present invention is completely green in process of production, pollution-free, low cost
Honest and clean, effect is significant, process is simple is adapted to industrial production.
Specific embodiment
With reference to embodiment, the present invention will be further described, but the embodiment is not as to limit of the invention
It is fixed.
Embodiment 1:
Contain in per 100g feed addictives：Xylo-oligosaccharide：27g, the Radix Astragali：5g, the fruit of Chinese wolfberry：3g, Radix Angelicae Sinensis：5g, Poria cocos：
4g, Psoralea corylifolia：5g, Semen Cuscutae：4g, the bighead atractylodes rhizome：4g, cellulase：6g, pectase：7g, β-glucose oxidase：7g, acidophilus breast
Clostridium：4g, Bacillus acidi lactici：8g, saccharomycete：6g, Bifidobacterium：5g.Above-mentioned material is crushed in pulverizer, 140 mesh sieves are crossed,
Uniformly mix according to the weight, that is, be made feed addictive.
Embodiment 2:
Contain in per 100g feed addictives：Xylo-oligosaccharide：27g, the Radix Astragali：8g, the fruit of Chinese wolfberry：7g, Radix Angelicae Sinensis：7g, Poria cocos：
9g, Psoralea corylifolia：6g, Semen Cuscutae：8g, the bighead atractylodes rhizome：5g, cellulase：6g, pectase：7g, β-glucose oxidase：7g.Will be above-mentioned
Material is crushed in pulverizer, crosses 140 mesh sieves, is uniformly mixed according to the weight, that is, be made feed addictive.
Embodiment 3:
Contain in per 100g feed addictives：Xylo-oligosaccharide：27g, cellulase：6g, pectase：7g, β-grape glycosyloxy
Change enzyme：7g, acidophilus breast clostridium：4g, Bacillus acidi lactici：8g, saccharomycete：6g, Bifidobacterium：5g.By above-mentioned material in pulverizer
Crush, cross 140 mesh sieves, uniformly mix according to the weight, that is, be made feed addictive.
Embodiment 4:
Contain in per 100g feed addictives：Xylo-oligosaccharide：27g, the Radix Astragali：5g, the fruit of Chinese wolfberry：3g, Radix Angelicae Sinensis：5g, Poria cocos：
4g, Psoralea corylifolia：5g, Semen Cuscutae：4g, the bighead atractylodes rhizome：4g, acidophilus breast clostridium：4g, Bacillus acidi lactici：8g, saccharomycete：6g, Bifidobacterium：
5g.Above-mentioned material is crushed in pulverizer, 140 mesh sieves are crossed, uniformly mixed according to the weight, that is, be made feed addictive.
Embodiment 5：Application of the present invention on child care pig
1. test objective：Compare the immunopotentiating composition of micro-powder of Chinese herbs, xylo-oligosaccharide, enzyme preparation and probiotics and be not added with
The nursery-stage pig feed of composition, the influence to child care pig.
2. experimental animal and experimental design
Adjacent 5 units, about 100 child care pigs (genetic background is similar, body weight is close, age in days is similar) are selected, with unit
For unit, it is divided into 5 groups, every group of 20 pig or so are randomly divided into 4 test groups and 1 control group；1 group is tested to add in daily ration
Plus the sample of 0.1% embodiment 1.Test 2 groups and the sample of 0.1% embodiment 2 is added in daily ration.3 groups are tested to be added in daily ration
The sample of 0.1% embodiment 3.Test 4 groups and the sample of 0.1% embodiment 4 is added in daily ration.5 groups are tested for control group, daily ration is fed
Based on daily ration.
3. daily ration and feeding and management are tested
This experiment is carried out on certain herding company pig farm.All are raised by the daily feeding manner in pig farm, and test group is because raising
Material has obvious Chinese herbal medicine smell, start experiment after need to being fed through the transitional period of reloading for 3 days, Manual material feeding, free choice feeding, freely drinks
Water.
(1) immunity inoculation and expelling parasite are routinely carried out；
(2) personal management, each group gives identical feeding and management and environmental condition；
(3) test pig morbidity in testing, should be under conditions of result of the test not be influenceed according to conventional treatment；
(4) each repeating groups inventory is recorded daily, if there is superseded or dead pig to register immediately, and claims this group of clout amount.
(5) observed and recorded：The feeding of daily viewing test pig, excrement and active situation, and make a record.
The test pig Diet Formula of table 1. and trophic level (%)
The test pig Diet Formula of table 1 and trophic level (%)
4. test index and assay method：
Weightening and daily gain：Positive on-test and at the end of, in units of head carrying out full group to test pig weighs；The side of weighing
Method：Stop eating when zero, 8：00-10：00 batch weighing successively, first activity 10 minutes has been fooled before weighing by pig, after it discharges fecaluria
Weigh, the first repeating groups of first each treatment group of weighing, second batch is weighed the second repeating groups for the treatment of group, and the rest may be inferred, directly
To having claimed.
5. health status is counted：
Diarrhea rate：Each group diarrhea rate during recording each group diarrhoea pig's head number, statistical test daily.
In units of repeating groups, feed consumption is counted daily；Surplus material should be reclaimed during off-test to weigh, feed consumption rate=inventory-
Surplus doses.
In units of repeating groups, the indexs such as its average weight, weightening, daily gain, feedstuff-meat ratio are calculated.
6. overall economic efficiency analysis：
With the feed cost as index that increases weight, Economic and Efficiency Analysis is carried out.Calculated by repeating groups, to dead, superseded pig
Feed consumption and weightening are compared.Weightening feed cost (unit/kg)=[full period mixed feed mean consumption expense (unit/kg)+full period enzyme
Preparation (or full period producing enzyme probiotic) average dose (g/) × enzyme preparation (or producing enzyme probiotic) unit price (unit/g)] ÷ full periods put down
Increase weight (kg/).
7. test site：
So-and-so herding company pig farm
8. test period：
Experimental period from May, 2016 No. 10 to June No. 25, wherein totally 37 days, pre-feeding period 5 days, positive 32 days phases of examination.
9. data processing and inversion：
Data are represented using " mean+SD " (X ± SD).
When calculating feedstuff-meat ratio and weightening feed cost, feed consumption rate and weightening value to dead, superseded pig are compared.
It is compared with daily gain, feedstuff-meat ratio and weightening feed cost subitem, and comprehensive commenting is carried out with reference to the colour of skin, digestion etc.
It is fixed.
10. test results and analysis
10.1 feeding experiments
10.1.1 pig body weight and average daily gain (being shown in Table 2) are tested
Each test group of table 2 and control group pig body weight and weightening
Table 2 is each treatment group pig body weight, net gain and average daily gain.From upper table, at experiment initial stage, each group pig
Weight differences not significantly (P>0.10).1 group is tested during experiment, 2 groups of experiment, 3 groups of experiment, 4 groups of experiment, control group increases day by day
It is respectively again：709 grams, 672.5 grams, 682 grams, 694 grams, 566 grams, addition 1 sample average daily gain of experiment is improved than control group
25.26%, addition 2 sample average daily gains of experiment improve 18.82% than control group, addition 3 sample average daily gains of experiment
20.49% is improved than control group, addition 4 sample average daily gains of experiment improve 22.61% than control group, and Analysis of variance is each
Not notable (the P of group difference>0.10).
10.1.2 pig feed consumption and feed conversion rate are tested
The feedstuff-meat ratio situation of each test group pig of table 3
As shown in Table 3, tested during experiment 1 group, 2 groups of experiment, 3 groups of experiment, experiment 4 groups of feed consumption rates difference it is very small, but with
Control group is all more compared to consumption；Test 1 group, 2 groups of experiment, 3 groups of experiment, 4 groups of feedstuff-meat ratios of experiment be respectively 1.90,1.98,
1.95th, 1.93,2.26,1 group of price of deed of experiment is superior to 2 groups of experiment, 3 groups of experiment, tests 4 groups and control group, significant difference,
It is with the obvious advantage.
Piggy diarrhoea situation during 10.2 experiments
The small diarrhea of pigs head number of days of table 4 and diarrhea rate
The ratio between diarrhea rate=diarrhoea head number of days and total number of days.
As shown in Table 4, tested during experiment 1 group, experiment 2 groups, experiment 3 groups, experiment 4 groups and control group diarrhea rate be respectively
5%th, 10%, 10%, 15%, 35%.Control group diarrhea rate highest is shown as, secondly 2 groups of experiment, test 3 groups, test 4 groups, examination
Test 1 group it is minimum.
10.3 each test group diets of different nutrition level detections
The each group of table 5 tests diets of different nutrition level laboratory detected value (%)
As can be seen here, add in small swine rationses containing xylo-oligosaccharide, Chinese herbal medicine micro mist, enzyme preparation and probiotic composition
Plus, to promote pig growth, improve efficiency of feed utilization, reduce piggy diarrhea rate, increasing economic efficiency has obvious effect.
Claims (6)
1. it is a kind of to be applied to the Immune-enhancing effect combination containing micro-powder of Chinese herbs, xylo-oligosaccharide, enzyme preparation and probiotics in livestock and poultry cultivation
Thing, it is characterised in that：The composition by micro-powder of Chinese herbs, xylo-oligosaccharide, enzyme preparation and probiotic group into.
2. one kind according to claim 1 is applied to contain micro-powder of Chinese herbs, xylo-oligosaccharide, enzyme preparation and benefit in livestock and poultry cultivation
The immunopotentiating composition of raw bacterium, it is characterised in that each component content in terms of parts by weight：
3. the one kind according to right 2 is applied to contain micro-powder of Chinese herbs, xylo-oligosaccharide, enzyme preparation and probiotics in livestock and poultry cultivation
Immunopotentiating composition, it is characterised in that the micro-powder of Chinese herbs and parts by weight meter content：
4. the one kind according to right 2 is applied to contain micro-powder of Chinese herbs, xylo-oligosaccharide, enzyme preparation and probiotics in livestock and poultry cultivation
Immunopotentiating composition, it is characterised in that the enzyme preparation and parts by weight meter content：
Cellulase：15-50 parts
Pectase：10-25 parts
β-glucose oxidase：5-30 parts.
5. the one kind according to right 2 is applied to contain micro-powder of Chinese herbs, xylo-oligosaccharide, enzyme preparation and probiotics in livestock and poultry cultivation
Immunopotentiating composition, it is characterised in that the probiotics and parts by weight meter content：
6. the one kind according to right 1 or 2 is applied to contain micro-powder of Chinese herbs, xylo-oligosaccharide, enzyme preparation and benefit in livestock and poultry cultivation
The immunopotentiating composition of raw bacterium, it is characterised in that be applied to livestock and poultry cultivation mistake as feed addictive immunopotentiating composition
Cheng Zhong, it is adaptable to all economic animals, addition part by weight is 0.05%-0.15%.
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| CN111528351A (en) * | 2020-06-09 | 2020-08-14 | 吴建东 | Traditional Chinese medicine probiotic feed additive and preparation method and use method thereof |
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