CN110279764A - A kind of fermented tcm additive and preparation method thereof improving poultry intestinal tract health - Google Patents

A kind of fermented tcm additive and preparation method thereof improving poultry intestinal tract health Download PDF

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Publication number
CN110279764A
CN110279764A CN201910642192.9A CN201910642192A CN110279764A CN 110279764 A CN110279764 A CN 110279764A CN 201910642192 A CN201910642192 A CN 201910642192A CN 110279764 A CN110279764 A CN 110279764A
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China
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chinese medicine
chinese
intestinal tract
fermented tcm
tract health
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Inventor
唐燕飞
刘举祥
黄文略
蒋华连
梁娟
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Guangxi Fufeng Agriculture And Animal Husbandry Group Co Ltd
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Guangxi Fufeng Agriculture And Animal Husbandry Group Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • A61K35/64Insects, e.g. bees, wasps or fleas
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/744Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/745Bifidobacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/744Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747Lactobacilli, e.g. L. acidophilus or L. brevis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11Pteridophyta or Filicophyta (ferns)
    • A61K36/12Filicopsida or Pteridopsida
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/19Acanthaceae (Acanthus family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284Atractylodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/287Chrysanthemum, e.g. daisy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/718Coptis (goldthread)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/734Crataegus (hawthorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/752Citrus, e.g. lime, orange or lemon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/756Phellodendron, e.g. corktree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12Antidiarrhoeals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/19Preparation or pretreatment of starting material involving fermentation using yeast, bacteria or both; enzymatic treatment

Abstract

The present invention provides a kind of fermented tcm additive for improving poultry intestinal tract health, including Chinese medicine and auxiliary material, Chinese medicine includes: the Chinese bulbul, the coptis, Cortex Phellodendri, Herba Andrographitis, phoenix-tail fern, wild chrysanthemum, Chinese gall, rhizoma atractylodis, polygonum flaccidum, dried orange peel, Divine Comedy, hawthorn, the auxiliary material includes calcium dihydrogen phosphate, and preparation method is that strain is added to ferment.Fermented tcm additive of the invention has the advantage that medicament sources are wide, and Chinese medicine is derived from naturally, naturally non-hazardous;Theory is advanced, there is an innate advantage of integration of drinking and medicinal herbs, and is particular about total tune, comprehensively regulating, treating both manifestation and root cause of disease, significant in efficacy;Traditional Chinese medicine ingredients are converted by probiotics, become small molecule by macromolecular, are easy to be absorbed by animal body, can effectively be decomposed some toxic components contained in Chinese medicine in fermentation process, be truly realized and have no toxic side effect;Beneficial bacterium is supplemented, enteritis is prevented, adjusts intestinal microecology balance, optimizes the price of deed, supplementing digestive enzyme helps enteron aisle to digest and assimilate, it is possible to reduce and the use of substitution part antibiotic.

Description

A kind of fermented tcm additive and preparation method thereof improving poultry intestinal tract health
Technical field
The invention belongs to field of biotechnology, and in particular to it is a kind of improve poultry intestinal tract health fermented tcm additive and Preparation method.
Technical background
As poultry diease complication is increasingly apparent, antibody-resistant bacterium is continuously emerged, and poultry intestinal tract health care is increasingly by culturist Attention.In the past, after fowl mass-sends raw disease, people are first it is envisioned that antiviral, anti-Escherichia coli secondary infection, is seldom examined Consider protection intestinal health.But since antibiotic is used for a long time, intestinal inflammatory is not only induced, immunosupress, nutrition are also created Imbalance, finally causes performance of poultry and the general level of the health gradually to decline.
Preventing and treating the most important approach of poultry disease now is that can inhibit disease to a certain degree using antibiotic The growth of opportunistic pathogen has the function that cure the disease, diseases prevention, but abuse of antibiotics be easy to cause the gastro-intestinal problems of poultry, and antibiosis Serious consequence such as antibody-resistant bacterium is continuously increased, antibiotic residue waits so long and seriously threatens the health of the mankind caused by element abuse, Through causing everybody concern.Feed addictive of the Chinese medicine as safety, follows always Traditional Chinese Medicine theory and the modern times are dynamic Object nutrition principle, have the characteristics that with food it is homologous, it is androgynous, with use, have nutrition and the double action of drug concurrently, be immunized live Property substance can enhance human body immune function, improve animal resisting stress, anti-disease ability, improve breeding performonce fo animals, while also Toxic side effect is small, has no drug resistance, is not easy the advantages that remaining.How reasonably to select to develop and utilize from Chinese medicine, extract beneficial Ingredient is simultaneously added in feed, for improving poultry intestinal tract health, becomes current urgent problem to be solved.
Summary of the invention
The purpose of the present invention is intended to provide a kind of fermented tcm additive, can effectively improve poultry intestinal tract health.
In order to achieve the above objectives, the fermented tcm additive of raising poultry intestinal tract health of the invention, including Chinese medicine with The weight ratio of auxiliary material, Chinese medicine and auxiliary material is 100:1;
The Chinese medicine includes the Chinese medicine of following parts by weight: Chinese bulbul 1450-1550, coptis 150-250, Cortex Phellodendri 300-400, Herba Andrographitis 250-350, phoenix-tail fern 250-350, wild chrysanthemum 150-250, Chinese gall 500-600, rhizoma atractylodis 300-400, polygonum flaccidum 250-350, dried orange peel 300-400, Divine Comedy 50-150, hawthorn 450-550;
The auxiliary material includes following components: calcium dihydrogen phosphate.
Preferably, the Chinese medicine includes the Chinese medicine of following parts by weight: the Chinese bulbul 1450, Cortex Phellodendri 300, is worn at the coptis 150 Heart lotus 250, phoenix-tail fern 250, wild chrysanthemum 150, Chinese gall 600, rhizoma atractylodis 400, polygonum flaccidum 350, dried orange peel 400, Divine Comedy 150, hawthorn 550。
Preferably, the Chinese medicine includes the Chinese medicine of following parts by weight: the Chinese bulbul 1500, the coptis 200, Cortex Phellodendri 350, punching Lotus 300, phoenix-tail fern 300, wild chrysanthemum 200, Chinese gall 550, rhizoma atractylodis 350, polygonum flaccidum 300, dried orange peel 350, Divine Comedy 100, hawthorn 500.
Preferably, the Chinese medicine includes the Chinese medicine of following parts by weight: the Chinese bulbul 1550, the coptis 250, Cortex Phellodendri 400, punching Lotus 350, phoenix-tail fern 350, wild chrysanthemum 250, Chinese gall 500, rhizoma atractylodis 300, polygonum flaccidum 250, dried orange peel 300, Divine Comedy 50, hawthorn 450.
The preparation method of the fermented tcm additive of the raising poultry intestinal tract health, steps are as follows:
1) it by above component weight weighing according to the ratio, mills and crushed 200 meshes, obtain herb powder;
2) solid state fermentation mode is used, by above-mentioned herb powder, accesses strain: DN-173010 plants of Bifidobacterium, lactobacillus fermenti CECT5716 pours into pure water, stirs, and is packed into fermentor, carries out anaerobic fermentation 7 days;
3) ferment after tank out, 40 DEG C constant temperature drying 8-12 hours, moisture content is down to 12.5-14%, finished product splitting packet is made Dress.
Further, in the step 2, the weight ratio for accessing Bifidobacterium DN-173010 plants and Chinese medicine is 1:100; The weight ratio for accessing lactobacillus fermenti CECT5716 and Chinese medicine is 0.6:100, the weight ratio of the pure water and Chinese medicine that pour into For 40:100.
Further, in step 2, at 35 DEG C~38 DEG C, relative humidity is controlled 60% for the fermentation temperature control of fermentor ~70%, 2 time/hour of speed of agitator, pH value is controlled in 6.5-6.8, and pressure inside the tank is set as 0.1MPa.
Primary raw material is illustrated below:
Cortex Phellodendri, wild chrysanthemum, Herba Andrographitis, phoenix-tail fern: clearing heat and detoxicating, antibacterial anti-inflammatory is slaked thirst and help produce saliva.
The Chinese bulbul, polygonum flaccidum, Chinese gall: sterilization stop dysentery, clearing heat-fire, inducing diaphoresis to dispel wind promote bacterial endotoxin discharge.
Since the digestion and absorption function of poultry digestive system is relatively simple, enteron aisle is shorter, when stagnation of the feed in enteron aisle Between it is also short, digestion time after food meal is crucial, and the Divine Comedy for promoting to digest and assimilate and hawthorn are targetedly added thus.Hair When dysentery characterized by white mucous stool occurs in existing family's poultry diease, illustrate to have infectd disease, mainly with Salmonella in digestive system acute infection, this bar Bacterium is stronger in digestive system reproductive capacity, declines digestive system function, since bacterium force is big, reduces glandular stomach digestive juice, from And enterogastric peristalsis enhances, bacterium invades intestinal mucosa, white paddle sample watery diarrhea occurs, at this moment illustrates that enterogastritis symptom occurs in poultry.
Divine Comedy, hawthorn: having the function of invigorating the spleen, relieving dyspepsia, reduces the loss of aqueous, corrects stomach healthy tendency, and righting is driven Heresy, so that liquid pH value is adjusted, to reach therapeutic purposes, for treating avian escherichia coli, salmonella, fowl Pasteur's bar Bacteriosis caused by bacterium etc. has unique curative effect to intractable enteric disorders.
All Chinese medicines in all Chinese medicine additives of the present invention derive from natural plants, and complicated component contains polysaccharide, biology A large amount of active constituents such as alkali, glycoside, volatile oil and tannin have multiple pharmacological effect, such as clearing heat and detoxicating, relieving cough and asthma, eliminating the phlegm Relieving sore-throat, tonifying middle-Jiao and Qi, spleen benefiting and stimulating the appetite, activating microcirculation and removing stasis medicinal, antidysentery with astringent, protection intestinal mucosa and strengthen immunity etc..
Intestinal inflammatory and symptom of irritable bowel syndrome can be alleviated for DN-173010 plants of Bifidobacterium used in institute of the invention, Prevent antibiotic-associated diarrhea etc..
The principle of fermented tcm additive of the present invention are as follows:
1, traditional Chinese medicine ingredients are using the bacterial strain probiotics that preferred beneficial bacteria of intestinal tract flora kefir milk bacillus and Bifidobacterium adapt to as bacterium Kind.
2, using microecology, bionic method, the intestines of animal body are simulated in vitro by way of biology grafting The digestion decomposable process of road environment and traditional Chinese medicine ingredients in vivo carries out biological conversion to effective component of chinese medicine, by the big of Chinese medicine Molecular substance, after become by microorganism conversion and Chinese medicine can be made to become fast by the small molecule ingredient that body enteron aisle directly absorbs The newtype drug of speed absorption, quantitatively curative effect.
3, contain sugar in Chinese medicinal formulae, required carbon source can be provided in fermentation for microorganism, in addition Chinese medicine itself Containing the nitrogen source that a large amount of cellulose provides, calcium dihydrogen phosphate is added, provides micro member necessary to it grows for microorganism Element-phosphorus, such formula combination be not only able to maintain the quick and mass propagation of microorganism, but also were able to maintain the permanent survival of microorganism.
4, in order to keep the faintly acid of fermented tcm, be conducive to the intestinal health with animal body, inhibit pernicious bacteria Growth, this fermentation process are to prevent from generating a large amount of acidic materials during the fermentation, it is necessary to while setting pH value, be used The comprehensive excessive acidic materials of EDTA liquid, keep the faintly acid state of fermented tcm.
Substantive distinguishing features and marked improvement of the invention are:
The fermented tcm additive of raising poultry intestinal tract health of the invention, has the advantages that
(1) this fermented tcm is added in Chinese medicine using specific probiotics as strain, product is made according still further to modern zymotechnique, It is a kind of new medicine fermentation processing system of full constituent fermentation liquid containing active ingredient of Chinese herbs, thallus and its metabolite Agent.
(2) medicament sources are wide: China's traditional Chinese medicine is resourceful, and Chinese medicine is derived from naturally, naturally non-hazardous.
(3) theory is advanced: this fermented tcm additive focuses on Overall View and diagnosis and treatment based on an overall analysis of the illness and the patient's condition to animal body, preventives treatment of disease Theory has the innate advantage of integration of drinking and medicinal herbs;And total tune is particular about, comprehensively regulating is treating both manifestation and root cause of disease, significant in efficacy.
(4) traditional Chinese medicine ingredients are converted by probiotics, become small molecule by macromolecular, are easy to be absorbed by animal body, be fermented Chinese materia medica tocixity can be decomposed in the process, be truly realized and have no toxic side effect.
(5) beneficial bacterium is supplemented, enteritis is prevented, adjusts intestinal microecology balance;Optimize the price of deed, supplement digestion Enzyme helps enteron aisle to digest and assimilate.
(6) this additive can reduce and substitute the use of part antibiotic.
(7) this additive sealed package avoids sunlight direct irradiation, under 15 DEG C of -28 DEG C of preservation conditions of room temperature, the shelf-life Up to 1 year.
(8) it is an optimal additive amount that adding proportion of this additive in feed, which is 0.2-0.3%, and process is multiple batches of The comparative test and comprehensive analysis of multi-dose, the additive amount of 0.2-0.3% can reach optimal raise benefit and After being excessively added, extra probiotics itself, which grows, also will largely consume nutriment, cause the effective consumption of nutriment.
Specific embodiment
Technical solution of the present invention is further illustrated below by specific embodiment.
Embodiment 1:
Following Chinese medicine: Chinese bulbul 1500g, coptis 200g, Cortex Phellodendri 350g, Herba Andrographitis 300g, phoenix-tail fern is weighed by weight 300g, wild chrysanthemum 200g, Chinese gall 550g, rhizoma atractylodis 350g, polygonum flaccidum 300g, dried orange peel 350g, Divine Comedy 100g, hawthorn 500g add up to 5000g.Following auxiliary material: calcium dihydrogen phosphate 50g is weighed by weight.
The preparation step of the preparation method of fermented tcm additive of the present invention is as follows:
1) by the above load weighted Chinese medicine and auxiliary material, milling crushed 200 meshes, obtain mixed-powder.
2) solid state fermentation mode is used, by above-mentioned mixed-powder, accesses strain: DN-173010 plants of Bifidobacterium, acidified milk Bacillus CECT5716, pours into pure water, is packed into fermentor after stirring, and carries out anaerobic fermentation 7 days.
Wherein, the weight ratio for accessing Bifidobacterium DN-173010 plants and Chinese medicine is 1:100(, that is, 50g);Access acidified milk The weight ratio of bacillus CECT5716 and Chinese medicine is 0.6:100(, that is, 30g);The weight ratio of the pure water and Chinese medicine that pour into is 40:100(, that is, 2000ml).The KRH-BPJ/GJ liquid production of hybrid seeds solid-state stainless steel fermentation tank that fermentor can be used as 20L volume.
In fermentation process, at 35~38 DEG C, relative humidity is controlled 60%~70%, is stirred for the fermentation temperature control of fermentor 2 time/hour of revolving speed is mixed, pH value is controlled in 6.5-6.8, and pressure inside the tank is set as 0.1MPa.
3) ferment after tank out, 40 DEG C constant temperature drying 8-12 hours, moisture content is down to 12.5-14%, finished product splitting is made Packaging.
Embodiment 2:
Following Chinese medicine: Chinese bulbul 1450g, coptis 150g, 300 g of Cortex Phellodendri, 250 g of Herba Andrographitis, phoenix-tail fern is weighed by weight 250 g, 150 g of wild chrysanthemum, 600 g of Chinese gall, 400 g of rhizoma atractylodis, 350 g of polygonum flaccidum, 400 g of dried orange peel, 150 g of Divine Comedy, hawthorn 550 g add up to 5000g.Following auxiliary material: calcium dihydrogen phosphate 50g is weighed by weight.
The preparation method is the same as that of Example 1.
Embodiment 3:
Following Chinese medicine: 1550 g of the Chinese bulbul, 250 g of the coptis, 400 g of Cortex Phellodendri, 350 g of Herba Andrographitis, phoenix-tail fern is weighed by weight 350 g, 250 g of wild chrysanthemum, 500 g of Chinese gall, 300 g of rhizoma atractylodis, 250 g of polygonum flaccidum, 300 g of dried orange peel, 50 g of Divine Comedy, hawthorn 450 G adds up to 5000g.Following auxiliary material: calcium dihydrogen phosphate 50g is weighed by weight.
The preparation method is the same as that of Example 1.
The cost of fermented tcm additive of the present invention (based on 5kg) are as follows: 276 yuan;Wherein Chinese medicine: 260 yuan;Auxiliary material: 10 Member;Fermentation processing: 5 yuan;Probiotics: 1 yuan.
Two kinds of application modes of the invention:
1, spice: additive amount is 0.2-0.3% in feed, and feed addition per ton increases about 106 yuan -160 yuan of cost;
2, it drinks water: fermented tcm filtering, it can be directly to drinking water for animals after being watered by 0.2% fermented tcm amount.
Experimental analysis: using the fermented tcm additive in embodiment 1, control group is unused for test group I, test group II Fermented tcm additive of the present invention.
1, the additive application method: is subjected to spice feeding by 0.2% in feed.
2, under same weather conditions, similar column home is mating to be given alms and identical feeding and management method, two groups of experiments Chicken group in daily Technical Follow-Up, chicken mass-sending it is raw have loose bowels, feed just and watery stool is few, and control group have much have loose bowels, The phenomenon that drawing feed just with watery stool.
3, test Efficiency Comparison analysis:
(1) test result is shown, two groups of chicken group means of test deliver 1.83 kilograms of weight for sale, compared with 1.77 kilograms/of control group 0.06 kilogram is weighed, average survival 92.65%, 91.4% compared with control group increases by 1 point 2 percentage point;Average food conversion Rate 3.67 reduces by 5.8% compared with control group 3.93;Every 1.53 yuan of chicken expenses for medicine, compared with 1.8 yuan/of control group, 0.27 yuan of saving/ Only.Peasant household cultivates profit, and experimental group be averaged 4.72 yuan of the profit of every chicken/only, 0.4 yuan high compared with 4.32 yuan/of contrast groups.
(2) 0.2% additive amount is pressed, it is 221 yuan that feed addictive per ton, which increases cost,;First group of chicken group of experiment uses Additive totle drilling cost increase by 8619 yuan, but full group feeds feed totle drilling cost reduces by 13437 yuan, and expenses for medicine reduces by 4118 yuan, survives Rate improves 0.8% than control group, and cultivation profit improves 3142 yuan, and three 20697 yuan total, deducts the increased cost of additive 8619 yuan, bringing benefits is 12078 yuan;The additive totle drilling cost that second group of chicken group uses increases by 9232 yuan, but second group of feed Totle drilling cost reduce by 9908 yuan, expenses for medicine reduce by 1801 yuan, survival rate than control group improve 1.7%, cultivation profit improve 5742 yuan, three Item is 17451 yuan total, deducts increased 9232 yuan of cost of additive, bringing benefits is 8219 yuan.
Test result shows the Chinese medicine additive for improvement Intestine of Broiler under summer high temperature high humidity stressed condition developed Obtain tangible result.
The above description is merely a specific embodiment, but scope of protection of the present invention is not limited thereto, any The change or replacement expected without creative work, should be covered by the protection scope of the present invention.Therefore, of the invention Protection scope should be determined by the scope of protection defined in the claims.

Claims (7)

1. a kind of fermented tcm additive for improving poultry intestinal tract health, which is characterized in that including Chinese medicine and auxiliary material, Chinese medicine Weight ratio with auxiliary material is 100:1;
The Chinese medicine includes the Chinese medicine of following parts by weight: Chinese bulbul 1450-1550, coptis 150-250, Cortex Phellodendri 300-400, Herba Andrographitis 250-350, phoenix-tail fern 250-350, wild chrysanthemum 150-250, Chinese gall 500-600, rhizoma atractylodis 300-400, polygonum flaccidum 250-350, dried orange peel 300-400, Divine Comedy 50-150, hawthorn 450-550;
The auxiliary material includes following components: calcium dihydrogen phosphate.
2. the fermented tcm additive according to claim 1 for improving poultry intestinal tract health, it is characterised in that: the Chinese medicine Material includes the Chinese medicine of following parts by weight: the Chinese bulbul 1450, the coptis 150, Cortex Phellodendri 300, Herba Andrographitis 250, phoenix-tail fern 250, mother chrysanthemum Spend 150, Chinese gall 600, rhizoma atractylodis 400, polygonum flaccidum 350, dried orange peel 400, Divine Comedy 150, hawthorn 550.
3. the fermented tcm additive according to claim 1 for improving poultry intestinal tract health, it is characterised in that: the Chinese medicine Material includes the Chinese medicine of following parts by weight: the Chinese bulbul 1500, the coptis 200, Cortex Phellodendri 350, Herba Andrographitis 300, phoenix-tail fern 300, wild chrysanthemum 200, Chinese gall 550, rhizoma atractylodis 350, polygonum flaccidum 300, dried orange peel 350, Divine Comedy 100, hawthorn 500.
4. the fermented tcm additive according to claim 1 for improving poultry intestinal tract health, it is characterised in that: the Chinese medicine Material includes the Chinese medicine of following parts by weight: the Chinese bulbul 1550, the coptis 250, Cortex Phellodendri 400, Herba Andrographitis 350, phoenix-tail fern 350, wild chrysanthemum 250, Chinese gall 500, rhizoma atractylodis 300, polygonum flaccidum 250, dried orange peel 300, Divine Comedy 50, hawthorn 450.
5. the preparation method of the fermented tcm additive according to claim 1 for improving poultry intestinal tract health, feature exist In steps are as follows:
1) it by above component weight weighing according to the ratio, mills and crushed 200 meshes, obtain herb powder;
2) solid state fermentation mode is used, by above-mentioned herb powder, accesses strain: DN-173010 plants of Bifidobacterium, lactobacillus fermenti CECT5716 pours into pure water, stirs, and is packed into fermentor, carries out anaerobic fermentation 7 days;
3) ferment after tank out, 40 DEG C constant temperature drying 8-12 hours, moisture content is down to 12.5-14%, finished product splitting packet is made Dress.
6. the preparation method of the fermented tcm additive according to claim 5 for improving poultry intestinal tract health, feature exist In: in the step 2, the weight ratio for accessing Bifidobacterium DN-173010 plants and Chinese medicine is 1:100;Access lactobacillus fermenti The weight ratio of CECT5716 and Chinese medicine is 0.6:100, and the weight ratio of the pure water and Chinese medicine that pour into is 40:100.
7. the preparation method of the fermented tcm additive according to claim 5 for improving poultry intestinal tract health, feature exist In: in step 2, the control of the fermentation temperature of fermentor is at 35~38 DEG C, and relative humidity control is 60%~70%, speed of agitator 2 Secondary/hour, pH value are controlled in 6.5-6.8, and pressure inside the tank is set as 0.1MPa.
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CN116327830A (en) * 2023-05-04 2023-06-27 海南医学院 Traditional Chinese medicine composition for resisting oxidization and regulating intestinal flora and preparation method thereof
CN116870114A (en) * 2023-08-15 2023-10-13 曾长林 Poultry preventive health care agent based on natural Chinese herbal medicines

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CN108102950A (en) * 2017-12-14 2018-06-01 广东科贸职业学院 A kind of preparation method and application of birds composite probiotics feed

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CN103495007A (en) * 2013-09-11 2014-01-08 丁玉兰 Traditional Chinese medicine microecologics preparation for preventing and treating pullorum disease and preparation method of microecologics preparation
CN108102950A (en) * 2017-12-14 2018-06-01 广东科贸职业学院 A kind of preparation method and application of birds composite probiotics feed

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CN116327830A (en) * 2023-05-04 2023-06-27 海南医学院 Traditional Chinese medicine composition for resisting oxidization and regulating intestinal flora and preparation method thereof
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Application publication date: 20190927