CN106818802A - Rosickyite azoles prevents and treats the bactericide of rice sheath blight disease with hexaconazole compounding - Google Patents
Rosickyite azoles prevents and treats the bactericide of rice sheath blight disease with hexaconazole compounding Download PDFInfo
- Publication number
- CN106818802A CN106818802A CN201710119425.8A CN201710119425A CN106818802A CN 106818802 A CN106818802 A CN 106818802A CN 201710119425 A CN201710119425 A CN 201710119425A CN 106818802 A CN106818802 A CN 106818802A
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- CN
- China
- Prior art keywords
- hexaconazole
- rosickyite azoles
- sheath blight
- bactericide
- rice sheath
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
- A01N47/10—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof
- A01N47/18—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof containing a —O—CO—N< group, or a thio analogue thereof, directly attached to a heterocyclic or cycloaliphatic ring
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
- A01N43/647—Triazoles; Hydrogenated triazoles
- A01N43/653—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
Abstract
The invention discloses the bactericide that rosickyite azoles and hexaconazole compounding prevent and treat rice sheath blight disease, the bactericide is with rosickyite azoles and hexaconazole as base-material, according to the compound disinfectant that the quality proportioning 1: 1~1: 4 of rosickyite azoles and hexaconazole is formulated.The compound disinfectant that the quality proportioning 1: 4 of preferred rosickyite azoles and hexaconazole is formulated.The rosickyite azoles is the rosickyite azoles active compound that mass fraction is 98%；The hexaconazole is the hexaconazole active compound of mass fraction 95.8%.Compound disinfectant of the invention, two kinds of base-materials do not chemically react, and with obvious synergy or are added effect, using safety, have a good cytotoxicity for the different types of Rhizoctonia solani Kuhn in current field, and apparently higher than rosickyite azoles or hexaconazole single dose.It is used to prevent and treat rice sheath blight disease suitable for vast rural area.
Description
Technical field
The present invention is relevant with bactericide, specifically, belongs to the bactericide containing organic compound, furthermore, it is understood that belonging to
Prevent and treat the bactericide of rice sheath blight disease.It is also to the plant caused by the sac fungus such as rust, powdery mildew, head blight, Fungi Imperfecti, basidiomycetes
Thing disease has preferable preventive effect.
Technical background
Rice sheath blight disease is also known as moire disease, popular name flower pin stalk, rotten pin pest, features spot.It is to be fallen ill by Rhizoctonia solani Kuhn infection,
It is many to occur under high temperature, super-humid conditions.Banded sclerotial blight causes harm seriously in South Rice Region of China, be two major diseases in current Rice Production it
One.The disease prevents paddy rice from earing or dead ears, blighted grain increase, and mass of 1000 kernel declines.
Rosickyite azoles is the third TBZ (Albendazole), is a kind of efficient, safety, broad spectrum activity azoles fungicide, to various
Plant disease has significant preventive effect, and has certain production-increasing function；Hexaconazole (hexaconazole), belongs to triazole bactericidal agent,
There are the protection and therapeutic action of broad spectrum activity to the fungi disease that especially Basidiomycota and Ascomycota cause.
In recent years, the patent application for preventing and treating rice sheath blight disease emerges in an endless stream, for example：Chinese patent application part 03132050.3
Number《A kind of Recompounded pesticide for preventing and treating rice sheath blight disease》, No. 200510115741.5《Rice sheath blight disease controlling agent》、
No. 200510023168.5《Application of the HEXAFLUMURON in rice sheath blight disease is prevented and treated》, No. 200910114526.1《One kind is for preventing
Control the ultra-low-volume composite reagent of rice sheath blight disease》, No. 201010294321.9《A kind of combination for preventing and treating rice sheath blight disease
Agricultural chemicals》, No. 201110389699.1《A kind of growth promotion simultaneously prevents and treats bactericide and its application of rice sheath blight disease》、
No. 201210401279.5《Prevent and treat the bactericidal composition of rice sheath blight disease》、201410241783.2《One kind preventing and treating rice banded sclerotial blight
The composite bactericide of disease》Deng.Wherein, No. 201210401279.5 disclose the bactericidal composition active ingredient for thifluzamide and
Rosickyite azoles；No. 201410241783.2 disclose the bactericidal composition active ingredient for Fluoxastrobin and rosickyite azoles.These bactericide
How effect is still not clear.The related application part for being compounded with rosickyite azoles and hexaconazole and preventing and treating rice sheath blight disease is there is no at present.
The content of the invention
The present invention is intended to provide rosickyite azoles prevents and treats the bactericide of rice sheath blight disease with hexaconazole compounding, it is to rice sheath blight disease
Mycelial growth have obvious inhibiting effect, vast rural area can be applied to and prevent and treat rice sheath blight disease, make cereal crops increasing production of rice
Increase income, be the development service of national economy.
Inventor carries out repeated screening to the agricultural chemicals with killing rice sheath blight disease germ activity, and to the original of Mixed Pharmacy
Material medicine quality proportioning carries out repetition test, and result of the test is contrasted, and another compound disinfectant is found, to rice sheath blight disease
Bacterium possesses stronger poisoning ability.
The compound disinfectant for preventing and treating rice sheath blight disease that inventor provides is with rosickyite azoles and hexaconazole as base-material, according to third
The quality proportioning 1 of sulphur azoles and hexaconazole: the composite bactericide that (1~4) is formulated.
By further preferred, the best in quality proportioning of rosickyite azoles and hexaconazole is 1: 4.
Above-mentioned rosickyite azoles is the active compound of mass fraction 98%, and above-mentioned hexaconazole is the active compound of mass fraction 95.8%.
The screening test of the above-mentioned composite bactericide raw material proportioning for preventing and treating rice sheath blight disease is as follows：
1 test objective：
With Rhizoctonia solani Kuhn as target, using mycelial growth rate method, test rosickyite azoles and hexaconazole single dose are to paddy rice
Sheath blight fungus Indoor antibacterial activity, and design and screening 5 proportioning combination synergy type when, seek rosickyite azoles oneself
Azoles alcohol has the optimum proportioning of collaboration or synergistic effect.
2 experimental designs
2.1 reagent agents are designed with test dose
98% rosickyite azoles active compound, 95.8% hexaconazole active compound are provided by Guizhou Daoyuan Biotechnology Co., Ltd..
2.2 for examination target
Rhizoctonia solani Kuhn [Rizoctonia solani], indoor Plantlet in vitro and culture；Normal temperature is preserved.Culture medium：
PDA。
2.3 test doses are designed
It is rosickyite azoles: hexaconazole=1 with effective ingredient: 1 as core, devises 1: 4,1: 2,1: 1,1: 0.5,1: 0.25 etc.
5 combinations, the test dose design such as table 1 after trial test.
The test dose of table 1 is designed
3 test methods
It is prepared by 3.1 pastille culture mediums
Rosickyite azoles DMF dissolves, and hexaconazole acetone solution is configured to mother liquor.Will test medicament and comparison medicament according to
Certain concentration gradient, is separately added into sterilized and is cooled to mixing in 45 DEG C or so of culture medium, pours into plate, is made pastille
Flat board.
3.2 toxicity tests
Using mycelium length rate method.A bacterium dish is connect in pastille flat board center, mycelia is down.25 DEG C are cultivated to blank bacterium
When cropping expires culture dish more than 2/3, the colony diameter of each treatment is measured.Each bacterium colony is measured 2 times by crossing method, flat with it
Mean represents the size of bacterium colony.Calculate suppression of the medicament to thalli growth rate.
3.3 evaluation methods：Co-toxicity coefficient method
Toxicity index × the B of content (the %)+B of the toxicity index × A of theoretical toxicity index TTI=A in mixture is mixed
Content (%) in agent
Co-toxicity coefficient is more than 120, shows there is synergistic effect；Show there is antagonism less than 80；Show have between 80~120
Summation action.
4 result of the tests
The toxicity test of 4.1 single doses
The toxicity test of the rosickyite azoles of table 2 and hexaconazole to rice sheath blight disease
Rosickyite azoles is respectively 0.1531 μ g/ml, 0.7536 μ g/ml, hexaconazole to EC50, EC90 value of Rhizoctonia solani Kuhn
EC50, EC90 value to Rhizoctonia solani Kuhn is respectively 0.0408 μ g/ml, 0.5037 μ g/ml.
4.2 rosickyite azoles and hexaconazole 5 are with the toxicity test for comparing rice sheath blight disease
The rosickyite azoles of table 3 matches somebody with somebody the toxicity test for comparing Rhizoctonia solani Kuhn with 5 compoundings of hexaconazole
5 EC50 values of proportioning are 0.0427~0.1343 μ g/ml, between two single doses；Proportioning 1: 4 and 1: 2
EC90 values are 0.6464 μ g/ml and 0.6668 μ g/ml, and activity matches 1: 1,1: 0.5 and 1: 0.25 between two single doses
EC90 values are that 0.09076~1.5026 μ g/ml activity is less than two single doses.
4.3 synergy evaluations
The rosickyite azoles of table 4 matches somebody with somebody the synergy evaluation for comparing rice sheath blight disease with 5 compoundings of hexaconazole
The co-toxicity coefficient of proportioning 1: 4,1: 2 and 1: 1 is respectively 111.98,86.96 and 81.15, and 120, table are less than more than 80
It is now summation action, and 1: 4>1∶2>1∶1；The co-toxicity coefficient of proportioning 1: 0.5 and 1: 0.25 is respectively 67.44 and 73.52, is less than
80, show as antagonism.
5 conclusions
Rosickyite azoles has good bacteriostatic activity to Rhizoctonia solani Kuhn with hexaconazole.Both compounding after, rosickyite azoles and oneself
The proportioning of azoles alcohol is 1: (1~4) is with summation action；Other proportionings then have antagonism.With reference to EC50, EC90, co-toxicity coefficient
Deng 3 indexs, selection 1: 4, i.e. 4 parts of 1 part of rosickyite azoles plus hexaconazole have synergy killing action for Rhizoctonia solani Kuhn.
Compound disinfectant of the invention, two kinds of base-materials do not chemically react, with obvious synergy or addition effect,
Using safety, there is a good cytotoxicity for the different types of Rhizoctonia solani Kuhn in current field, and apparently higher than rosickyite azoles
Or hexaconazole single dose.It is used to prevent and treat rice sheath blight disease suitable for vast rural area.
Specific embodiment
The mass fraction that the ︰ of embodiment 1 takes Guizhou Daoyuan Biotechnology Co., Ltd.'s production is 98% rosickyite azoles active compound
The hexaconazole active compound 10kg of the mass fraction 95.8% of 2.5kg, Zai Qu Jiangyin Suli Chemicals Co., Ltd. production is base-material,
It is re-dubbed the compound disinfectant that 12.5kg prevents and treats rice sheath blight disease.
The mass fraction that the ︰ of embodiment 2 takes Guizhou Daoyuan Biotechnology Co., Ltd.'s production is 98% rosickyite azoles active compound
The hexaconazole active compound 2.5kg of the mass fraction 95.8% of 2.5kg, Zai Qu Jiangyin Suli Chemicals Co., Ltd. production is base
Material, is re-dubbed the compound disinfectant that 5.0kg prevents and treats rice sheath blight disease.
Above two compound disinfectant is used through Guizhou somewhere, obtains the good result for preventing and treating rice sheath blight disease.
Claims (3)
1. rosickyite azoles and hexaconazole compounding prevent and treat the bactericide of rice sheath blight disease, it is characterised in that the bactericide be with rosickyite azoles and
Hexaconazole is base-material, according to the compound disinfectant that the quality proportioning 1: 1~1: 4 of rosickyite azoles and hexaconazole is formulated.
2. according to the bactericide that rice sheath blight disease is prevented and treated described in claim 1, it is characterised in that the bactericide be with rosickyite azoles and
Hexaconazole is base-material, according to the compound disinfectant that the quality proportioning 1: 4 of rosickyite azoles and hexaconazole is formulated.
3. according to the bactericide that rice sheath blight disease is prevented and treated described in claim 1, it is characterised in that the rosickyite azoles is mass fraction
It is 98% rosickyite azoles active compound；The hexaconazole is the hexaconazole active compound of mass fraction 95.8%.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710119425.8A CN106818802A (en) | 2017-03-02 | 2017-03-02 | Rosickyite azoles prevents and treats the bactericide of rice sheath blight disease with hexaconazole compounding |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710119425.8A CN106818802A (en) | 2017-03-02 | 2017-03-02 | Rosickyite azoles prevents and treats the bactericide of rice sheath blight disease with hexaconazole compounding |
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| Publication Number | Publication Date |
|---|---|
| CN106818802A true CN106818802A (en) | 2017-06-13 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710119425.8A Withdrawn CN106818802A (en) | 2017-03-02 | 2017-03-02 | Rosickyite azoles prevents and treats the bactericide of rice sheath blight disease with hexaconazole compounding |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109042702A (en) * | 2018-09-21 | 2018-12-21 | 贵州道元生物技术有限公司 | A kind of rosickyite azoles and the bactericidal composition of difenoconazole and application thereof for preventing and treating rice sheath blight disease |
| CN109105384A (en) * | 2018-10-22 | 2019-01-01 | 贵州道元生物技术有限公司 | A kind of combination sterilization composition for preventing and treating pear tree black heart |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105961379A (en) * | 2016-05-04 | 2016-09-28 | 南京高正农用化工有限公司 | Large composition floating granule for preventing and controlling sheath blight and rice blast of rice, and preparation method thereof |
| CN106359415A (en) * | 2016-08-29 | 2017-02-01 | 广东中迅农科股份有限公司 | Pesticidal composition containing albendazole and triazole fungicide |
-
2017
- 2017-03-02 CN CN201710119425.8A patent/CN106818802A/en not_active Withdrawn
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105961379A (en) * | 2016-05-04 | 2016-09-28 | 南京高正农用化工有限公司 | Large composition floating granule for preventing and controlling sheath blight and rice blast of rice, and preparation method thereof |
| CN106359415A (en) * | 2016-08-29 | 2017-02-01 | 广东中迅农科股份有限公司 | Pesticidal composition containing albendazole and triazole fungicide |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109042702A (en) * | 2018-09-21 | 2018-12-21 | 贵州道元生物技术有限公司 | A kind of rosickyite azoles and the bactericidal composition of difenoconazole and application thereof for preventing and treating rice sheath blight disease |
| CN109105384A (en) * | 2018-10-22 | 2019-01-01 | 贵州道元生物技术有限公司 | A kind of combination sterilization composition for preventing and treating pear tree black heart |
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Application publication date: 20170613 |