CN107242242A - Bactericidal composition comprising folpet and prothioconazoles - Google Patents
Bactericidal composition comprising folpet and prothioconazoles Download PDFInfo
- Publication number
- CN107242242A CN107242242A CN201710653089.5A CN201710653089A CN107242242A CN 107242242 A CN107242242 A CN 107242242A CN 201710653089 A CN201710653089 A CN 201710653089A CN 107242242 A CN107242242 A CN 107242242A
- Authority
- CN
- China
- Prior art keywords
- bactericidal composition
- prothioconazoles
- folpet
- disease
- composition according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/02—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having no bond to a nitrogen atom
- A01N47/04—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having no bond to a nitrogen atom containing >N—S—C≡(Hal)3 groups
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
- A01N43/647—Triazoles; Hydrogenated triazoles
- A01N43/653—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
Abstract
The invention discloses a kind of bactericidal composition comprising folpet and prothioconazoles, the weight ratio of folpet and prothioconazoles is 20 in the bactericidal composition:1‑1:10, preferably 5:1‑1:1.The bactericidal composition of the present invention can be prepared into the regular dosage forms such as missible oil, wettable powder, water dispersible granules, suspending agent, microemulsion, microcapsule suspending agent, granule by customary preparation methods, preventing and treating of the bactericidal composition of the present invention to various crop disease shows obvious synergistic function, is particularly suitable for preventing and treating rice sheath blight disease.
Description
Technical field
The invention belongs to composition pesticide field, and in particular to be a kind of sterilization group comprising folpet and prothioconazoles
Polymer composition and its purposes for preventing and treating corps diseases.
Background technology
Rice sheath blight disease, also known as moire disease.Seedling stage can all fall ill to ear period.Leaf sheath is caught an illness produces dirty-green at approximately level
Water soaking mode edge blurry stigma, the big oval or moire shape of rear flaring, middle part is in grayish green or taupe, and middle part is in when humidity is low
Yellowish or canescence, middle part disorganization is translucent shape, and edge is dun.Several scabs merge to form serious disease when falling ill serious
Spot, in irregular moire spot, often causes yellow leaf withered.Blade catches an illness scab also in moire shape, edge yellow fading, during rapid onset
Scab rots quickly in dirty green, blade, and stalk damage symptoms are like blade, and the later stage is in yellowish-brown, easy to break.Fringe neck portion is aggrieved to be just
Dirty green, it is rear graying brown, it can not often ear, the not plump paddy of heading is more, mass of 1000 kernel declines.During high humidity, sick minister goes out white net
Shape mycelia, after pool white hypha group, form sclerotium, sclerotium dark brown is easy to fall off.One layer is produced under hot conditions on scab
The white mould layer of powder is the load and basidiospore of germ.
Prothioconazoles, english common name is prothioconazole, is sterol demethylation（DMI）Or ergosterol
Biosynthesis inhibitor, it not only has a good systemic action, excellent protection, treats and roots out activity, and the lasting period
It is long.Substantial amounts of table of field test results is bright, and prothioconazoles not only have good security to crop, and preventing disease theraping effect is good,
And volume increase is obvious.Compared with triazole bactericidal agent, prothioconazoles have wider fungicidal spectrum.Prothioconazoles are mainly used in preventing
Control many diseases on the crops such as wheat, barley, rape, peanut, paddy rice, beans, beet and field vegetables.Especially on cereal
Eye spot, banded sclerotial blight, mildew, and by Septoria musiva（Septoria spp.）, sickle-like bacteria（Fusarium spp.）And beak
Spore bacterium（Rhynchosporium spp.）The disease superior activity Deng caused by.Almost have anti-well to all wheat class diseases
Powdery mildew, banded sclerotial blight, glume blight on effect, such as wheat and barley, leaf spot, rust, sclerotiniose, net blotch, moire disease, base are rotten
Disease etc.；Rape and Peanut Fields soil-borne disease, such as sclerotiniose, and main foliage disease, such as gray mold, blackspot can effectively be prevented and treated
Disease, brown spot, balck shank, sclerotiniose and rust etc.；It is additionally operable to preventing and treating Cabbage Leaf Spot etc..
Folpet is organosulfureous fungicide, is mainly used in the multiple diseases such as preventing and treating cereal crops, vegetables, fruit tree, and to planting
Thing plays the role of stimulating growth, can prevent and treat rice blast, rice sheath blight disease, wheat rust, oilseed rape downy mildew, leaf spot of peanut, horse
Bell potato late blight, early blight of tomato etc., folpet can be used with systemic fungicide mixture, delay absorbability drug resistance to send out
Exhibition.
Practice have shown that, chemical agent, which is used for a long time, is easily caused the drug-fast generation of pathogen, causes consumption to continue to increase,
Risk increase, is unfavorable for sustainable development, and agriculture chemical compounding is to solve one of main path that resistance occurs, and at present, is not yet sent out
The existing relevant report compounded on folpet and prothioconazoles.
The content of the invention
Based on case above, have that synergistic effect, prevention effect be good, use cost it is an object of the invention to provide one kind
Low, environment amenable bactericidal composition.
The purposes for preventing and treating corps diseases another object of the present invention is to provide the bactericidal composition to be used for, the agriculture
Crop disease includes but is not limited to banded sclerotial blight, false smut, powdery mildew, downy mildew etc..
In order to achieve the above object, the present invention is adopted the following technical scheme that：
A kind of bactericidal composition, the bactericidal composition active component includes folpet and prothioconazoles, wherein, folpet and third
The weight ratio of sulphur bacterium azoles is 20:1-1:10.
It is preferred that, the weight ratio of folpet and prothioconazoles is 5 in the bactericidal composition:1-1:1.
Further, the weight percentage of active component is 5-90%, preferably 20- in bactericidal composition of the invention
70%。
Further, bactericidal composition of the invention and the adjuvant or carrier merga pass mixed in the proper ratio are molten
Solution, it is scattered, suspend, mixing, the conventional meanses such as absorption are prepared into any one type of dosage form for being adapted to agriculturally use, including but
It is not limited to missible oil, wettable powder, water dispersible granules, suspending agent, microemulsion, microcapsule suspending agent, granule etc..
Further, bactericidal composition of the invention can be used directly, it is preferred that bactericidal composition of the invention with extremely
The few form of mixtures of a kind of agriculturally acceptable adjuvant or carrier together uses them.Suitable adjuvant or carrier one
As for be to crop it is safe, particularly in some cases, the adjuvant at least should with the present invention bactericidal composition
Do not chemically react.
Further, bactericidal composition of the invention prevents and treats various corps diseases by the following method：Directly or use water
After diluting or being suspended in water in the proper ratio, to prevent and treat the effective dose of corps diseases, being applied to expection can go out
On the crops of existing disease, or it is not intended to the place that plant disease occurs or grown.
Further, the application dosage of bactericidal composition of the invention preventing and treating corps diseases is for example prevented with various factors
Control target, plant growth stage, disease occurrence degree, weather, environmental condition, type of preparation, application process and time of application etc.
And change.
Further, bactericidal composition of the invention can also be true with killing for for example other species of other agricultural active compositions
The mixing such as microbial inoculum, insecticide, nematicide, herbicide, synergist, safener, fertilizer is applied.
Further, bactericidal composition of the invention, which is particularly suitable for use in, prevents and treats rice sheath blight disease.
Compared with prior art, bactericidal composition of the invention has the beneficial effect that：
（1）Active component folpet and prothioconazoles component compounding are reasonable in the bactericidal composition of the present invention, can be used in control
Preferable prevention effect is kept in the case of the cost of medicine；
（2）Active component is by the selection of compound proportion in the bactericidal composition of the present invention, to crops in certain scope
The preventing and treating of disease shows obvious synergistic function, it is possible to reduce pesticide activity component usage amount, improves prevention effect；
（3）The active component mechanism of action is different in the bactericidal composition of the present invention, and in controlling disease, both are used in conjunction with
The action site of agricultural chemicals can be increased, and then overcome or delay the development of pathogen resistance；
（4）The bactericidal composition of the present invention has no adverse effects to beneficial natural enemy to crop safety, is conducive to the sustainable development of agricultural chemicals
Exhibition.
Embodiment
In order that the object, technical solutions and advantages of the present invention are more clearly understood, carried out below in conjunction with specific embodiment
Illustrate, but the present invention is limited to absolutely not these examples.
First, toxicity is determined
1st, controlling object：Rice sheath blight disease（Rhizoctonia solania）.
2nd, test method：The test medicine that active compound is configured to need, test method reference《Farm-chemical indoor determination is tried
Test the part of criterion bactericide the 4th：Suppress disease fungus mycelial growth experiment Plating》With《Farm-chemical indoor determination experiment is accurate
The then part of bactericide the 6th：The synergy of mixture is determined》.
Single dose and each Mixed Pharmacy are set into various concentrations gradient（On the basis of pilot study, bacteriostasis rate is 5%~90%
In the range of by geometric progression setting）.Aseptically, the sterilising medium melted in advance is quantitatively added according to test process
Enter in sterile conical flask, reach that high concentration quantitatively draws decoction successively from low concentration, be separately added into above-mentioned conical flask, fully shake
It is even.Then equivalent is poured into 4 a diameter of 9cm culture dish, and the pastille flat board of respective concentration is made.If the processing without medicament
Blank control is done, often processing is repeated 4 times.
By cultured rice sheath blight disease pathogen aseptically, with a diameter of 5mm sterilization punchers, from bacterium colony
Edge cuts bacteria cake, bacterium disease is inoculated in into pastille flat board center with inoculator, mycelia up, covers ware lid, puts preference temperature
Incubator in cultivate.Pathogen mycelial growth situation is investigated according to the growing state of bacterium in blank control culture dish.Use slide calliper rule
Colony diameter is measured, unit is millimeter（mm）, each bacterium colony it is each once with crossing method vertical survey diameter, take it to be averaged
Value.Regression analysis is made according to each drug concentration logarithm value and corresponding mycelial growth inhibition rate niqueMin, the EC of each medicament is obtained50
Value.
The co-toxicity coefficient of mixture is calculated with the abundant methods of Sun Yun（CTC）, activity of the reagent agent to germ is evaluated with this.Compounding
The co-toxicity coefficient of preparation（CTC）>=120 show as synergistic effect；CTC≤80 show as antagonism；80 ＜ CTC ＜ 120 are showed
For summation action.
Folpet and prothioconazoles compounding are as shown in table 1 to the Toxicity Determination result of rice sheath blight disease：
Folpet and prothioconazoles compounding are as shown in table 1 to the prevention effect of rice sheath blight disease, as can be seen from Table 1, folpet
20 after being compounded with prothioconazoles:1-1:In the range of 10 to the co-toxicity coefficient of rice sheath blight disease controlling more than 120, performance
For synergistic function；Wherein, when both compound proportions are 7:When 4, synergistic function is best, it is contemplated that both costs and
Compound proportion, the most worth further research of the ratio.
2nd, example of formulations
1st, embodiment 1:40% folpet prothioconazoles water dispersible granules（1:1）
Folpet 20%
Prothioconazoles 20%
Naphthalenesulfonate formaldehyde condensation compound 5%
Polycarboxylate 3%
Sodium acid carbonate 2%
Sucrose 2%
Kaolin surplus
The preparation technology of the water dispersible granules is：By pesticide activity component, filler is mixed together with dispersant, wetting agent, disintegrant
Close uniform, crushed with micro jet, through mediating, then add and granulated in fluidized-bed granulation dryer, dry, sieve
Through sampling analysis after point, you can the water dispersible granules of the present composition are made.
2nd, embodiment 2：33% folpet prothioconazoles wettable powder（10:1）
Folpet 30%
Prothioconazoles 3%
Neopelex 4%
Sodium lignin sulfonate 5%
White carbon 20%
Bentonite surplus
The preparation method of the wettable powder is：Active ingredient and dispersant, wetting agent and filler are mixed, in stirred tank
Middle stirring is with producing the wettable powder.
3rd, embodiment 3:55% folpet prothioconazoles suspending agent（7:4）
Folpet 35%
Prothioconazoles 20%
AEO 4%
NPE 3%
Lignosulfonates 3%
Xanthans 1.8%
Glycerine 4%
C10Fatty alcohol 1%
Bronopol 0.3%
Deionized water surplus
The preparation method of the suspending agent is：By above-mentioned formula, using deionized water as medium, by active compound, dispersant, wetting agent,
Thickener, defoamer etc., which are added in high-speed shearing emulsion machine, shears about 30 min, then after being sanded with sand mill, you can this is made
The described suspending agent of invention.
3rd, field control effectiveness test
1st, controlling object：Rice sheath blight disease
2nd, test method：With example of formulations 1-3 and comparison medicament（Respectively 50% folpet wettable powder, 480g/L rosickyite
Bacterium azole suspending agent）Rice sheath blight disease field control effectiveness test is prevented and treated, and viewing test medicament and comparison medicament are to rice sheath blight disease
Security.
Trial crops are paddy rice, and kind is military remote stalk 23.Prevent and treat rice sheath blight disease field control effectiveness test reference《Field efficacy
Test rule (one) GB/T 17980.26-2000 bactericidal agent for preventing and treating rice sheath blight diseases》Carry out field control effectiveness test.Test medicine,
Comparison medicament and the processing of the cell of blank control are using the arrangement of random district's groups, plot area 30m2, 4 repetitions, investigation before dispenser
State of an illness radix, altogether dispenser twice, before each dispenser and 7 days after last time dispenser, 15 days investigation prevention effects.It is random per cell
4 points of investigation are taken, look into two plants, and the whole piece leaves of every plant of investigation, result of the test is as shown in table 2 at every.
Stage division (in units of blade)：
0 grade：Disease-free spot；
1 grade：Lesion area accounts for less than the 5% of whole leaf area；
3 grades：Lesion area accounts for the 6%-10% of whole leaf area；
5 grades：Lesion area accounts for the 11%-25% of whole leaf area；
7 grades：Lesion area accounts for the 26%-50% of whole leaf area；
9 grades：Lesion area accounts for more than the 50% of whole leaf area.
Drug effect computational methods：
In formula：CK0、CK1The respectively forward and backward disease index of blank district dispenser, PT0、PT1Respectively chemicals treatment district is applied
The forward and backward disease index of medicine.
Field control effectiveness test result is as shown in table 2, as can be seen from Table 2, to paddy rice after folpet and prothioconazoles compounding
The prevention effect of banded sclerotial blight is also different under different amounts, wherein, the composition pesticide of embodiment 1,3 is used in active ingredient
Measure for 350g/ hectares when, prevention effect is more than 79%, hence it is evident that be better than control single dose prevention effect.In addition, in medication model
Do not find that the medicament of the embodiment of the present invention and reference examples has poisoning generation to rice crop in enclosing, show the pesticide combination of the present invention
Thing is worthy of popularization to crop safety.
Claims (9)
1. a kind of bactericidal composition, it is characterised in that active component includes folpet and prothioconazoles.
2. bactericidal composition according to claim 1, it is characterised in that the weight ratio of the folpet and prothioconazoles is
20:1-1:10。
3. bactericidal composition according to claim 2, it is characterised in that the weight ratio of the folpet and prothioconazoles is
5:1-1:1。
4. bactericidal composition according to claim 2, it is characterised in that the weight ratio of the folpet and prothioconazoles is
7:4。
5. the bactericidal composition according to any one of claim 1-4 claim, it is characterised in that the Bactericidal composite
Thing can be prepared into any one formulation used in suitable agricultural production.
6. bactericidal composition according to claim 5, it is characterised in that the formulation of the bactericidal composition is missible oil, can
It is any in WP, water dispersible granules, suspending agent, microemulsion, microcapsule suspending agent, granule.
7. bactericidal composition according to claim 5, it is characterised in that the bactericidal composition can be with other agricultural work
Property composition is used in conjunction with.
8. the bactericidal composition according to any one of claim 1-7 claim is used to prepare preventing and treating corps diseases
Application in medicine.
9. application according to claim 8, it is characterised in that the corps diseases are preferably rice sheath blight disease.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710653089.5A CN107242242A (en) | 2017-08-02 | 2017-08-02 | Bactericidal composition comprising folpet and prothioconazoles |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710653089.5A CN107242242A (en) | 2017-08-02 | 2017-08-02 | Bactericidal composition comprising folpet and prothioconazoles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107242242A true CN107242242A (en) | 2017-10-13 |
Family
ID=60012615
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710653089.5A Pending CN107242242A (en) | 2017-08-02 | 2017-08-02 | Bactericidal composition comprising folpet and prothioconazoles |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107242242A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114206114A (en) * | 2019-06-05 | 2022-03-18 | Upl有限责任公司 | Fungicide compositions for controlling conidiobolus fermentation in plants |
| WO2023002475A1 (en) * | 2021-07-17 | 2023-01-26 | Adama Makhteshim Ltd. | Aqueous fungicide mixture formulation |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1252690A (en) * | 1997-04-18 | 2000-05-10 | 拜尔公司 | Fungicide active substance combinations |
| CN106857599A (en) * | 2017-04-27 | 2017-06-20 | 广东广康生化科技股份有限公司 | A kind of bactericidal composition containing pyraclostrobin and folpet and its application |
-
2017
- 2017-08-02 CN CN201710653089.5A patent/CN107242242A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1252690A (en) * | 1997-04-18 | 2000-05-10 | 拜尔公司 | Fungicide active substance combinations |
| CN106857599A (en) * | 2017-04-27 | 2017-06-20 | 广东广康生化科技股份有限公司 | A kind of bactericidal composition containing pyraclostrobin and folpet and its application |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114206114A (en) * | 2019-06-05 | 2022-03-18 | Upl有限责任公司 | Fungicide compositions for controlling conidiobolus fermentation in plants |
| WO2023002475A1 (en) * | 2021-07-17 | 2023-01-26 | Adama Makhteshim Ltd. | Aqueous fungicide mixture formulation |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN105961399B (en) | Bactericidal composition and its application | |
| CN105191946A (en) | Sterilization composition and application thereof | |
| CN108184854A (en) | A kind of bactericidal composition and its application containing cyazofamid | |
| CN103271094A (en) | Compound bactericide | |
| CN102657186A (en) | Bactericidal composition containing thifluzamide and prothioconazole | |
| CN101946792A (en) | Azoxystrobin-prochloraz complex bactericide and application thereof | |
| CN103053561A (en) | Benthiavalicarb isopropyl containing bactericidal composition | |
| CN102696614B (en) | Trifloxystrobin-containing compound pesticide bactericidal composition and preparation | |
| CN101828575A (en) | Pyrimidine nucleoside antibiotic and propiconazole compound bactericide | |
| CN105211075A (en) | Bactericidal composition and application thereof | |
| CN106489956A (en) | Composition pesticide and its application | |
| CN107242242A (en) | Bactericidal composition comprising folpet and prothioconazoles | |
| CN104542585A (en) | Fungicide composition and application thereof | |
| CN103478153B (en) | A kind of bactericidal composition containing Boscalid and benzene metsulfovax | |
| CN102657180B (en) | Sterilization composition containing tetraconazole and trifloxystrobin | |
| CN101642109B (en) | Bactericidal composition containing famoxadone | |
| CN105265434A (en) | Pesticide composition containing fludioxonil | |
| CN107318865A (en) | The composition pesticide of captan and furametpyr compounding | |
| CN103355309A (en) | Sterilization composition and preparation thereof | |
| CN104041496B (en) | A kind of composite bactericide | |
| CN106689148A (en) | Pesticide composition containing dichloroxazole and dimethomorph | |
| CN107306980A (en) | A kind of shenqinmycin composite bactericide and its application | |
| CN101632383B (en) | Pesticide composition and application thereof | |
| CN108782578A (en) | Composition pesticide containing folpet and fluorine azoles bacterium aniline | |
| CN102657185B (en) | Sterilization combination containing thifluzamide and tetraconazole |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20171013 |