CN103053561A - Benthiavalicarb isopropyl containing bactericidal composition - Google Patents
Benthiavalicarb isopropyl containing bactericidal composition Download PDFInfo
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- CN103053561A CN103053561A CN2013100413616A CN201310041361A CN103053561A CN 103053561 A CN103053561 A CN 103053561A CN 2013100413616 A CN2013100413616 A CN 2013100413616A CN 201310041361 A CN201310041361 A CN 201310041361A CN 103053561 A CN103053561 A CN 103053561A
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Abstract
The invention discloses a benthiavalicarb isopropyl containing bactericidal composition. An effective active ingredient is composed of a first active ingredient and a second active ingredient, wherein the first active ingredient is benthiavalicarb isopropyl, the second active ingredient is selected from strobilurin fungicide azoxystrobin, kresoxim-methyl, metominostrobin, fluoxastrobin, picoxystrobin or coumoxystrobin, the weight ratio of the first active ingredient to the second active ingredient is (1:10)-(8:1), preferably (1:8)-(5:1). The composition can be prepared into agriculturally allowable water dispersible granules, wettable powder and suspending agent dosage forms. The bactericidal composition disclosed by the invention is reasonable in ingredients, good in bactericidal effect and low in medicine application cost, and the activity and bactericidal effect of the bactericidal composition are not the simple combination of the activities of ingredients, so that compared with the existing single preparations, the bactericidal composition not only has a significant bactericidal effect but also has a significant synergistic effect, is low in medicine application cost and good in safety, has no pollution to crops, and conforms to the safety requirements of pesticide preparations. The bactericidal composition disclosed by the invention has a significant control effect on downy mildew, powdery mildew, rice blast and sheath blight of crops.
Description
Technical field
The present invention relates to a kind of bactericidal composition that contains benzene metsulfovax and methoxy acrylic bactericide, active component is comprised of Fluoxastrobin, kresoxim-methyl, SSF 126, fluoxastrobin, ZEN 90160 or the SYP-3375 that the first active component benzene metsulfovax and the second active component are selected from methoxy acrylic bactericide, belongs to technical field of compounded pesticide.
Background technology
The benzene metsulfovax; English common name: benthiavalicarb-isopropyl; chemical name: [[(6-fluoro benzothiazole-2-yl)-ethylamino formoxyl]-2-methyl-propyl] carbamic acid isopropyl ester is the new type bactericide of being developed jointly by combinatorial chemistry industrial group and Ihara company.The benzene metsulfovax has good activity to the Oomycete fungal disease, has very strong prevention, treatment, osmotically active, and good lasting effect and resistance of rainwater washing against are arranged.
The methoxy acrylic acid series bactericidal agent is in recent years bactericide kind newly developed, is a large milestone in the bactericide field.Methoxy acrylic bactericide has unique mechanism of action, the active group of this series bactericidal agent is methoxy acrylic acid (ester/acid amides), the cytochrome b el compound of Main Function in the mitochondrial respiratory chain of fungi, thus the growth of electronics transmission Antifungi stoped.Have protection, treat, root out, infiltration, systemic activity, and can be in plant corpus, very fast degraded in soil and the water.Although this series bactericidal agent mechanism of action is unique, the same with other bactericide, methoxy acrylic bactericide also is unable to escape the misfortune of resistance, and use cost is high, uses so limited the spread of methoxy acrylic acid series bactericidal agent.
The below introduces the methoxy acrylic acid series bactericidal agent kind relevant with the present invention.
Fluoxastrobin, other Chinese name: the Amici reaches, English common name: azoxystrobin, chemical name: (E) 2-[2-[6-(2-cyano-benzene oxygen) pyrimidine-4-yl oxygen] phenyl]-the 3-methoxy-methyl acrylate.Efficiently, wide spectrum; almost can prevent and treat all fungal diseases; as powdery mildew, rust, glume blight, net blotch, downy mildew, rice blast etc. are all had good activity, have protection, root out, infiltration and systemic action, can suppress the sprouting of spore and the growth of mycelia.Can be used for cauline leaf processing, seed treatment, also can carry out soil treatment.Suitable crop is cereal, paddy rice, grape, potato, vegetables, fruit tree, beans and other crop etc.
Kresoxim-methyl, other Chinese name: emerald green shellfish, English common name: kresoxim-methyl, chemical name: methyl (E)-2-methoxyimino-2-[2-(O-toloxyl) phenyl] acetate.Kresoxim-methyl can suppress Spores and invade; has good prolection; kresoxim-methyl has good activity to fungus-caused multiple diseases such as imperfect fungus, sac fungi, basidiomycetes, Oomycetes; as: the diseases such as grape powdery mildew, wheat rust, potato late blight, pumpkin epidemic disease, rice blast, especially to powdery mildew of strawberry, melon powdery mildew, powdery mildew of cucumber, pear scab special efficacy.
SSF 126, English common name: metominostrobin: chemical name: (E)-2-methoxyimino-N-methyl-2-(2-phenoxy phenyl) acetamide.SSF 126 is the methoxy acrylic broad-spectrum germicide of the wild adopted company of Japanese salt exploitation, has protection, roots out, infiltration and therapeutic action, is mainly used in preventing and treating the diseases such as rice blast, powdery mildew, downy mildew, before disease occurs or the emergence period use.Suitable crop is paddy rice, wheat, fruit tree and vegetables etc.
Fluoxastrobin, English common name: fluoxastrobin, chemical name: 2-[6-(2-chlorophenoxy)-5-FU-4-base oxygen] and phenyl } (5,6-dihydro-Isosorbide-5-Nitrae, 2-dioxazine-3-yl) ketone O-methyloxime.Fluoxastrobin is the interior absorption cauline leaf processing bactericide of Bayer Cropscience Co.,Ltd's report; it is wide that it uses optimum period; no matter early stage at fungal infection; or can both provide extraordinary protection and therapeutic action at growth period of hypha, can effectively prevent and treat in the crops such as cereal crop, potato, vegetables and coffee nearly all fungal disease such as rust, glume blight, powdery mildew, downy mildew etc.Have to hit fast and kill and long double grading of lasting period, crop is had good compatibility.
ZEN 90160, English common name: Picoxystrobin, chemical name: (E)-3-methoxyl group-2-{2-[6-(trifluoromethyl)-2-pyridine oxygen methyl] phenyl } methyl acrylate.ZEN 90160 is Syngenta Co.,Ltd's exploitation, and it is fast that this product has infiltration rate, and systemic activity is compared with existing methoxy acrylate bactericide, and wheat leaf blight, net blotch and moire disease are had stronger result for the treatment of.Be mainly used in preventing and treating wheat rust, powdery mildew; Leaf rust of barley etc.Increase yield significantly.
SYP-3375, English common name: coumoxystrobin, chemical name: (E)-and 2-(2-((3-butyl-4-methyl-coumarin-7-Ji-oxygen base) methyl) phenyl)-the 3-methoxy-methyl acrylate.Have protection and therapeutic action; a kind of disinfectant use in agriculture of high-efficiency broad spectrum, to by mastigomycetes, in conjunction with bacterium, sac fungi, basidiomycetes, and the plant disease that causes of imperfect fungus such as sclerotinia rot of colza, apple valsa canker, rice blast, sigatoka, alternaria leaf spot of apple etc. good preventive effect is arranged.
Although the benzene metsulfovax has preferably preventive effect to the Oomycete fungal disease, its mechanism of action is single, and controlling object is single, exists resistance risk after the listing, cause preventive effect to reduce, and use cost is high.
Summary of the invention
It is reasonable to the purpose of this invention is to provide a kind of component, and synergistic effect is remarkable, and bactericidal effect is good, and drug cost is low, and fungicidal spectrum is wide, is difficult for developing immunity to drugs, to the agricultural bactericidal composition of crop safety.
Another object of the present invention provides the application of above-mentioned bactericidal composition in control crops downy mildew, powdery mildew, rice blast, banded sclerotial blight.
In order to overcome the defective of existing unitary agent, the present invention proposes following solution.
A kind of bactericidal composition that contains the benzene metsulfovax, its active component is:
(1) first active component benzene metsulfovax;
(2) second active components are Fluoxastrobin, kresoxim-methyl, SSF 126, fluoxastrobin, ZEN 90160 or the SYP-3375 that is selected from methoxy acrylic bactericide;
The weight ratio of the first active component and the second active component is 1:10～8:1, is preferably more preferably 1:5～2:1 of 1:8～5:1, most preferably is 1:2～1:1.
The content sum of the first active component and the second active component is 5%～85% of described composition total weight, is preferably 10%～75%.
It is water dispersible granules, wetting powder or suspending agent etc. that the present invention contains the preparation formulation that the bactericidal composition of benzene metsulfovax can prepare according to method known in those skilled in the art.
For water dispersible granules, those skilled in the art are familiar with the corresponding auxiliary agent of use and finish the present invention very much.In dispersant such as polycarboxylate, lignosulfonates, the alkylnaphthalene sulfonate one or more; In wetting agent such as alkyl sulfate, alkylsulfonate, the naphthalene sulfonate one or more; In disintegrant such as ammonium sulfate, urea, sucrose, the glucose one or more; In binding agent such as diatomite, corn starch, PVA, carboxymethyl (ethyl) cellulose family one or more; Filler such as diatomite, kaolin, white carbon, fine particle calcium carbonate, talcum powder, attapulgite, potter's clay one or more.
To wetting powder, spendable auxiliary agent has: in dispersant such as polycarboxylate, lignosulfonates, the alkylnaphthalene sulfonate one or more; In wetting agent such as alkyl sulfate, alkylsulfonate, the naphthalene sulfonate one or more; Filler such as ammonium sulfate, urea, sucrose, glucose, diatomite, kaolin, white carbon, fine particle calcium carbonate, talcum powder, attapulgite, potter's clay one or more.
To suspending agent, spendable auxiliary agent has: dispersant such as polycarboxylate, lignosulfonates, alkylnaphthalene sulfonate (dispersing agent NNO), TERSPERSE 2020(U.S. Huntsman Corporation produce the alkyl naphthalene sulfonic acid salt) in one or more; Phenethyl phenol polyoxyethylene poly-oxygen propylene aether), among the TERSPERSE 4894 one or more the Arlacel-60 APEO), agricultural newborn 1601#(common name sorbitan monostearate), Tween-60 #(common name alkyl phenol formaldehyde resin polyoxyethylene ether), farming breast 2201, this dish-60#(common name emulsifier such as Nongru-700 #(common name::::; Among wetting agent such as alkylphenol-polyethenoxy base ether formaldehyde condensation products sulphate, alkylphenol-polyethenoxy base ether phosphate, phenethyl phenol polyethenoxy base ether phosphate, alkyl sulfate, alkylsulfonate, naphthalene sulfonate, the TERSPERSE 2500 one or more; In thickener such as xanthans, polyvinyl alcohol, bentonite, the aluminium-magnesium silicate one or more; In preservative such as formaldehyde, benzoic acid, the Sodium Benzoate one or more; Defoamer such as organic silicon defoamer; In antifreezing agent such as ethylene glycol, propane diols, glycerine, urea, inorganic salts such as the sodium chloride one or more; Water is deionized water.
The inventor finds by test; the benzene metsulfovax that the mechanism of action is different and prevent and treat the bactericide compounded of Oomycete class disease has significant synergies, and control efficiency, the expanding prevention that can significantly improve treatment, protection are composed; reduce cost accounting, high to crop safety.Component of the present invention is reasonable, and treatment adds protective effect, and bactericidal effect is good, and drug cost is low, and its active and bactericidal effect is not the simple superposition of each composition activity, but significant synergistic effect is arranged, and is good to crop safety, meets the security requirement of pesticidal preparations.The present invention has preferably control efficiency to crops downy mildew, powdery mildew, rice blast, banded sclerotial blight.
Embodiment
Illustrate that below by Toxicity Determination benzene metsulfovax and methoxy acrylic bactericide Fluoxastrobin, kresoxim-methyl, SSF 126, fluoxastrobin, ZEN 90160 or SYP-3375 are mixed to the synergistic effect of downy mildew, powdery mildew, rice blast, banded sclerotial blight.
In order to prevent and treat the downy mildew in the agricultural production, the inventor has carried out mutual composite synergy research with benzene metsulfovax and above-mentioned methoxy acrylic bactericide, and concrete grammar is: it is tested object that bacterium of downy mildew of cucumber (Pseudoperonospora cubensis) is adopted in test.Test method is with reference to " the agricultural industry criteria NY/T1156.3-2006 of the People's Republic of China (PRC) ".At first single dose and each Mixed Pharmacy are arranged 5 variable concentrations gradients (on preliminary experiment result's basis, different with proportioning according to different medicament combinations, the concentration gradient setting is also different, and bacteriostasis rate is set) in 5%～90% scope.Test target bacterium is to pick up from the from up to down bacterium of downy mildew of cucumber blade of 4 leaves～6 leaf positions of field, wash the Pseudoperonospora cubensis sporangium of vacuum side of blade with 4 ℃ of distilled water, be made into suspension (concentration is controlled at every milliliter of 1 * 105～1 * 107 sporangium), deposit under 4 ℃ for subsequent use; Liquid is evenly sprayed in the healthy leaves back side, behind the liquid natural air drying, each is processed blade and blade go up dorsad, by being emitted in the moisture preservation box behind the marks for treatment.Test is established the processing that does not contain medicament and is made blank.Be inoculated in vacuum side of blade with ready fresh sporangia suspension drop 10 μ L.4 of every blade inoculations, every processing are no less than 5 leaves.24h inoculation before processing.Ware lid on the inoculation bonnet places climatic cabinate or the humidistat of illumination is arranged, the continuous illumination in every day/dark 12h alternately, temperature is 17 ℃～22 ℃, cultivates under the condition of relative moisture more than 90%.Depending on processing and the measurement of blank incidence and record scab diameter, unit is millimeter (mm), calculates control efficiency.The EC of each medicament is obtained in linear regression analysis between probit value by control efficiency and the logarithm value of series concentration
50Value with the co-toxicity coefficient (CTC) of the abundant method calculating of Sun Yun mixture, is estimated reagent agent to the activity of germ with this.
The co-toxicity coefficient of complex preparation (CTC) 〉=120 shows as synergistic effect; CTC≤80 show as antagonism; 80＜CTC＜120 show as summation action.
Toxicity Determination result shows: benzene metsulfovax and methoxy acrylic bactericide Fluoxastrobin, kresoxim-methyl, SSF 126, fluoxastrobin, ZEN 90160, SYP-3375 are used with take weight ratio as 1:10～8:1 has preferably virulence to cucumber downy mildew, preferably synergistic effect is all arranged, especially take weight ratio as 1:8～5:1 synergy is the most remarkable.
In order to prevent and treat crop powdery mildew, the inventor has carried out mutual composite synergy research with benzene metsulfovax and Fluoxastrobin, kresoxim-methyl, SSF 126, fluoxastrobin, ZEN 90160, SYP-3375, and concrete grammar is: subjects is powdery mildew of cucumber bacterium sphaerotheca fuliginea.Former medicine is mixed with the test medicine that needs, and test method is with reference to " the agricultural industry criteria NY/T1156.11-2008 of People's Republic of China (PRC) farm-chemical indoor determination test rule bactericide the 11st part: control cucurbits powdery mildew test pot-culture method ".At first single dose and each Mixed Pharmacy are arranged 5 variable concentrations gradients (on preliminary experiment result's basis, different with proportioning according to different medicament combinations, the concentration gradient setting is also different, and preventive effect is set by geometric progression) in 5%～90% scope.With the pure water that is added with a small amount of surfactant (Tween 80), wash and get the fresh spore that covers with on the Powdery Mildew cucumber leaves, filter with double gauze, making spore concentration is 1 * 10
5The suspension of individual spore/milliliter, for subsequent use.Every processing 3 basins repeat for 4 times, and establish the processing that only contains solvent and surfactant and do not contain effective composition and make blank.With spore suspension 24h inoculation before chemicals treatment, liquid is evenly sprayed in the blade face to all wetting, for subsequent use behind the liquid natural air drying.Then potted plant cucumber natural air drying after inoculation and the chemicals treatment moves to thermostatic chamber, cultivates 7 days～10 days under the condition of 20 ℃～24 ℃ of temperature.Treat that the sick leaf rate of blank reaches 80% when above, classification investigation is managed incidence everywhere, and 30 leaves are investigated in every processing at least, and grade scale is:
0 grade: anosis;
1 grade: lesion area accounts for below 5% of one-piece blade area;
3 grades: lesion area accounts for 6%～15% of one-piece blade area;
5 grades: lesion area accounts for 16%～25% of one-piece blade area;
7 grades: lesion area accounts for 26%～50% of one-piece blade area;
9 grades: lesion area accounts for 50%～75% of one-piece blade area;
11 grades: lesion area accounts for more than 75% of one-piece blade area.
The EC of each medicament is obtained in linear regression analysis between probit value by preventive effect and the logarithm value of series concentration
50Value with the co-toxicity coefficient (CTC) of the abundant method calculating of Sun Yun mixture, is estimated reagent agent to the activity of germ with this.
The co-toxicity coefficient of complex preparation (CTC) 〉=120 shows as synergistic effect; CTC≤80 show as antagonism; 80＜CTC＜120 show as summation action.
Toxicity Determination result shows: benzene metsulfovax and methoxy acrylic bactericide Fluoxastrobin, kresoxim-methyl, SSF 126, fluoxastrobin, ZEN 90160 or SYP-3375 are used with take weight ratio as 1:10～8:1 has preferably virulence to powdery mildew of cucumber, preferably synergistic effect is all arranged, especially take weight ratio as 1:8～5:1 synergy is the most remarkable.
In order to prevent and treat rice blast, the banded sclerotial blight in the agricultural production, the inventor has carried out mutual composite synergy research with benzene metsulfovax and Fluoxastrobin, kresoxim-methyl, SSF 126, fluoxastrobin, ZEN 90160, SYP-3375, and concrete grammar is:
Subjects is respectively Pyricularia oryzae (Pyriculariagrisea), Rhizoctonia solani Kuhn (Rhizoctonia solani), former medicine is mixed with the test medicine that needs, and test method is with reference to " the agricultural industry criteria NY/T1156.2-2006 of the People's Republic of China (PRC) ".At first single dose and each Mixed Pharmacy are arranged 5 variable concentrations gradients (on preliminary experiment result's basis, different with proportioning according to different medicament combinations, the concentration gradient setting is also different, and bacteriostasis rate is set by geometric progression) in 5%～90% scope.If the clear water contrast repeats 3 times.Adopting the mycelial growth rate method, with cultured pathogen, is 5 mm card punch with diameter under aseptic condition, cuts the bacterium cake from colony edge, with transfer needle the bacterium cake is connected on the culture medium flat plate of different drug concentrations, puts in 27 ℃, saturated humidity incubator and cultivates; When treating that the control group bacterium colony covers with, measure colony diameter, calculate the percentage that each chemicals treatment suppresses mycelial growth, the EC of each medicament is obtained in the linear regression analysis between the probit value by inhibiting rate and the logarithm value of series concentration
50Value with the co-toxicity coefficient (CTC) of the abundant method calculating of Sun Yun mixture, is estimated reagent agent to the activity of germ with this.
The co-toxicity coefficient of complex preparation (CTC) 〉=120 shows as synergistic effect; CTC≤80 show as antagonism; 80＜CTC＜120 show as summation action.
Toxicity Determination result shows: benzene metsulfovax and methoxy acrylic bactericide Fluoxastrobin, kresoxim-methyl, SSF 126, fluoxastrobin, ZEN 90160 or SYP-3375 are used with take weight ratio as 1:10～8:1 has preferably virulence to rice blast, rice sheath blight disease, preferably synergistic effect is all arranged, especially take weight ratio as 1:8～5:1 synergy is the most remarkable.
Below in conjunction with embodiment content of the present invention is described further.
Example of formulations 1
Take by weighing 7% benzene metsulfovax, 56% Fluoxastrobin, 3% TERSPERSE 2700(polycarboxylate, U.S. Huntsman Corporation produces), 3% dispersing agent NNO (alkylnaphthalene sulfonate formaldehyde condensation products), 2% Nekal BX (nekal), 2% K-12(lauryl sodium sulfate), 1% carboxymethyl cellulose, 5% urea, diatomite add to 100% weight portion.The method of the frequent regulation of above-mentioned raw materials water intaking dispersible granule is namely mixed, ultra micro air-flow crushing, mixing, granulation step are produced 63% benzene metsulfovax azoxystrobin water dispersible granule.
Example of formulations 2
Take by weighing 20% benzene metsulfovax, 65% kresoxim-methyl, 2%TERSPERSE 2700,1% dispersing agent NNO, 2% Nekal BX, 2%K-12,1% carboxymethyl cellulose, 2% urea, diatomite and add to 100% weight portion.The method of the frequent regulation of above-mentioned raw materials water intaking dispersible granule is namely mixed, ultra micro air-flow crushing, mixing, granulation step are produced 85% benzene metsulfovax water dispersion granules agent of Kresoxim.
Example of formulations 3
Take by weighing 10% benzene metsulfovax, 50% SSF 126,3% TERSPERSE 2700,3% dispersing agent NNO, 2% Nekal BX, 1%K-12,1% carboxymethyl cellulose, 3% urea, diatomite and add to 100% weight portion.The method of the frequent regulation of above-mentioned raw materials water intaking dispersible granule is namely mixed, ultra micro air-flow crushing, mixing, granulation step are produced 60% benzene metsulfovax SSF 126 water dispersible granules.
Example of formulations 4
Take by weighing 21% benzene metsulfovax, 7% fluoxastrobin, 3% TERSPERSE 2700,2% dispersing agent NNO, 3% Nekal BX, 2%K-12,3% diatomite, 5% glucose, kaolin and add to 100% weight portion.The method of the frequent regulation of above-mentioned raw materials water intaking dispersible granule is namely mixed, ultra micro air-flow crushing, mixing, granulation step are produced 28% benzene metsulfovax fluoxastrobin water dispersible granules.
Example of formulations 5
Take by weighing 8% benzene metsulfovax, 32% ZEN 90160,3% TERSPERSE 2700,3% dispersing agent NNO, 2% Nekal BX, 1%K-12,1% carboxymethyl cellulose, 3% urea, diatomite and add to 100% weight portion.The method of the frequent regulation of above-mentioned raw materials water intaking dispersible granule is namely mixed, ultra micro air-flow crushing, mixing, granulation step are produced 40% benzene metsulfovax ZEN 90160 water dispersible granules.
Example of formulations 6
Take by weighing 12% benzene metsulfovax, 36% SYP-3375,4% TERSPERSE 2700,2% dispersing agent NNO, 2% Nekal BX, 2%K-12,3% corn starch, 5% sulphur ammonium, attapulgite and add to 100% weight portion.The method of the frequent regulation of above-mentioned raw materials water intaking dispersible granule is namely mixed, ultra micro air-flow crushing, mixing, granulation step are produced 48% benzene metsulfovax SYP-3375 water dispersible granules.
Example of formulations 7
Take by weighing 20% benzene metsulfovax, 20% Fluoxastrobin, 3% calcium lignosulfonate, 2% Nekal BX, 2%K-12,2% White Carbon black, kaolin and add to 100% weight portion.Above-mentioned raw materials makes 40% benzene metsulfovax Fluoxastrobin wetting powder through mixing behind the air-flow crushing.
Example of formulations 8
Take by weighing 5% benzene metsulfovax, 50% kresoxim-methyl, 4% calcium lignosulfonate, 3% TERSPERSE 2700,2% Nekal BX, 2%K-12,3% White Carbon black, fine particle calcium carbonate and add to 100% weight portion.Above-mentioned raw materials makes 55% benzene metsulfovax kresoxim-methyl wetting powder through mixing behind the air-flow crushing.
Example of formulations 9
Take by weighing 64% benzene metsulfovax, 8% SSF 126,4% calcium lignosulfonate, 4% dispersing agent NNO, 2% Nekal BX, 2%K-12,10% White Carbon black, attapulgite and add to 100% weight portion.Above-mentioned raw materials makes 72% benzene metsulfovax SSF 126 wetting powder through mixing behind the air-flow crushing.
Example of formulations 10
Take by weighing 7% benzene metsulfovax, 42% fluoxastrobin, 4% calcium lignosulfonate, 3% TERSPERSE 2700,2% Nekal BX, 2%K-12,3% White Carbon black, fine particle calcium carbonate and add to 100% weight portion.Above-mentioned raw materials makes 49% benzene metsulfovax fluoxastrobin wetting powder through mixing behind the air-flow crushing.
Example of formulations 11
Take by weighing 45% benzene metsulfovax, 9% ZEN 90160,5% calcium lignosulfonate, 2% Nekal BX, 2%K-12,5% White Carbon black, kaolin and add to 100% weight portion.Above-mentioned raw materials makes 54% benzene metsulfovax ZEN 90160 wetting powder through mixing behind the air-flow crushing.
Example of formulations 12
Take by weighing 7% benzene metsulfovax, 28% SYP-3375,2% dispersing agent NNO, 2% Nekal BX, 2%K-12, attapulgite and add to 100% weight portion.Above-mentioned raw materials makes 35% benzene metsulfovax SYP-3375 wetting powder through mixing behind the air-flow crushing.
Example of formulations 13
Taking by weighing 24% benzene metsulfovax, 8% Fluoxastrobin, 5% TERSPERSE 4894(U.S. Huntsman Corporation produces), 2% TERSPERSE 2500(U.S. Huntsman Corporation produces), 3% TERSPERSE 2020(U.S. Huntsman Corporation produces), 0.2% xanthans, 5% propane diols, 0.5% benzoic acid, 0.5% silicone defoaming agent (trade name: s-29 Nanjing "four news" (new ideas applied chemistry product company produces), deionized water add to 100% weight portion.Above-mentioned raw materials is through mixing, and high speed shear is disperseed 30min, with making 32% benzene metsulfovax Fluoxastrobin suspending agent behind the sand mill sand milling.
Example of formulations 14
Take by weighing 15% benzene metsulfovax, 30% kresoxim-methyl, 4%TERSPERSE 4894,1.5%TERSPERSE 2500,2%TERSPERSE 2020,1% aluminium-magnesium silicate, 0.2% xanthans, 5% ethylene glycol, 0.5% formaldehyde, 0.5% silicone defoaming agent, deionized water and add to 100% weight portion.Above-mentioned raw materials is through mixing, and high speed shear is disperseed 30min, with making 45% benzene metsulfovax kresoxim-methyl suspending agent behind the sand mill sand milling.
Example of formulations 15
Take by weighing 20% benzene metsulfovax, 10% SSF 126,5%TERSPERSE 4894,2%TERSPERSE 2500,1%TERSPERSE 2020,0.2% xanthans, 5% propane diols, 0.5% benzoic acid, 1% epoxychloropropane, 0.5% silicone defoaming agent, deionized water and add to 100% weight portion.Above-mentioned raw materials is through mixing, and high speed shear is disperseed 30min, with making 30% benzene metsulfovax SSF 126 suspending agent behind the sand mill sand milling.
Example of formulations 16
Take by weighing 2% benzene metsulfovax, 3% fluoxastrobin, 2%TERSPERSE 2020,2% this dish-60#, 2% Tween-60 #, 1%TERSPERSE 2500,0.5% white carbon, 0.3% xanthans, 5% ethylene glycol, 0.5% benzoic acid, 0.5% silicone defoaming agent, deionized water and add to 100% weight portion.Above-mentioned raw materials is through mixing, and high speed shear is disperseed 30min, with making 5% benzene metsulfovax fluoxastrobin suspending agent behind the sand mill sand milling.
Example of formulations 17
Take by weighing 20% benzene metsulfovax, 5% ZEN 90160,1%TERSPERSE 2020,3% agricultural newborn 1601#, 2% agricultural newborn 2201#, 1%TERSPERSE 2500,0.3% xanthans, 5% ethylene glycol, 0.5% formaldehyde, 0.5% silicone defoaming agent, deionized water and add to 100% weight portion.High speed shear is disperseed 30min, with making 25% benzene metsulfovax ZEN 90160 suspending agent behind the sand mill sand milling.
Example of formulations 18
Take by weighing 20% benzene metsulfovax, 10% SYP-3375,3%TERSPERSE 4894,1.5%TERSPERSE 2500,1%TERSPERSE 2020,0.2% xanthans, 5% propane diols, 0.5% benzoic acid, 0.5% silicone defoaming agent, deionized water and add to 100% weight portion.Above-mentioned raw materials is through mixing, and high speed shear is disperseed 30min, with making 30% benzene metsulfovax SYP-3375 suspending agent behind the sand mill sand milling.
Biological Examples 1: prevent and treat the downy mildew of garpe field trial
Downy mildew is one of important disease of grape, the blade of mainly causing harm, also cause harm inflorescence and young fruit.The inventor in 2012 in Shaanxi the thoughtful example of formulations 7(40% benzene metsulfovax Fluoxastrobin wetting powder that carried out), example of formulations 14(45% benzene metsulfovax kresoxim-methyl suspending agent), example of formulations 15(30% benzene metsulfovax SSF 126 suspending agent), example of formulations 10(49% benzene metsulfovax fluoxastrobin wetting powder), example of formulations 5(40% benzene metsulfovax ZEN 90160 water dispersible granules), example of formulations 18(30% benzene metsulfovax SYP-3375 suspending agent) prevents and treats the downy mildew of garpe field trial, verified that these several medicaments are to the control efficiency of downy mildew of garpe with to the safety of grape.Test method is with reference to " GB/T 17980.122-2004 pesticide field efficacy medicine test criterion (two) the bactericidal agent for preventing and treating downy mildew of garpe test of pesticide effectiveness ".Trial crops is grape, and controlling object is downy mildew of garpe (Plasmopara viticola).The test kind is huge peak, and the age of tree 8 years grows fine.Be the level land experimental field, fertility is better, experimental field the cultivation condition uniformity.Test medicine and dosage see table 5 for details.Other establishes blank, and every processing 3 times repeats, 8 trees in every residential quarter, and totally 42 residential quarters, district's group is arranged at random.Use the sprayer even spraying.For the first time dispenser when blade begins to see morbidity, the again dispenser 1 time every 10 days, dispenser is 2 times altogether.
Investigation and statistical method:
Behind the medicine 7 days for the second time, pumping was newly climing then for 10 of every residential quarter random searchings, investigates whole blades from top to bottom, records the sick numbers of sheets at different levels and total number of sheets by following stage division.
Blade stage division:
0 grade: without scab;
1 grade: lesion area accounts for below 5% of whole leaf area;
3 grades: lesion area accounts for 6%～25% of whole leaf area;
5 grades: lesion area accounts for 26%～50% of whole leaf area
7 grades: lesion area accounts for 51%～75% of whole leaf area;
9 grades: lesion area accounts for more than 75% of whole leaf area.
Disease index and control efficiency computational methods:
Disease index=[∑ (the sick numbers of sheets at different levels * relative level numerical value)/(investigating total number of sheets * 9)] * 100
Control efficiency (%)=[(contrast disease index-processing disease index)/contrast disease index] * 100
Security survey and on the impact of other biological: sprayed behind the medicine the 1st day at every turn and medicine after some days, each is processed on grape growth with on the impact of other diseases to observe medicament.
Field test results shows, 40% benzene metsulfovax Fluoxastrobin wetting powder, 45% benzene metsulfovax kresoxim-methyl suspending agent, 30% benzene metsulfovax SSF 126 suspending agent, 49% benzene metsulfovax fluoxastrobin wetting powder, 40% benzene metsulfovax ZEN 90160 water dispersible granules, 30% benzene metsulfovax SYP-3375 suspending agent has good control efficiency to downy mildew of garpe, dilute respectively 3000 times, 2500 times, 2500 times, 2500 times, 2000 times, 2500 times of sprayings, investigation in 7 days after the dispenser second time, sick leaf rate contrast obviously reduces, preventive effect is respectively 87.62%, 89.56%, 86.03%, 82.55%, 81.83%, 89.20%, obviously be better than 1000 times of 10% benzene metsulfovax suspending agents, 1000 times of 25% Fluoxastrobin suspending agents, 1000 times of 25% kresoxim-methyl suspending agents, 1000 times of 30% SSF 126 wetting powders, 1000 times of 30 fluoxastrobin wetting powders, 1000 times of 30% ZEN 90160 water dispersible granules, 1500 times of preventive effects to downy mildew of garpe of 25% SYP-3375 suspending agent, difference arrives utmost point significance level.
Duration of test is observed, and each chemicals treatment does not produce the poisoning phenomenon to grape leaf, the tender tip.
After result of the test shows that benzene metsulfovax and Fluoxastrobin, kresoxim-methyl, SSF 126, fluoxastrobin, ZEN 90160, SYP-3375 are mixed, obviously improved the control efficiency to downy mildew of garpe, dosage and drug cost have been reduced, to grape growth safety, it is the desirable medicament of preventing and treating downy mildew of garpe.
Biological Examples 2: control rice blast field trial
Carried out example of formulations 1(63% benzene metsulfovax azoxystrobin water dispersible granule at Shaanxi Province's Hanzhong City in 2012), example of formulations 14(45% benzene metsulfovax kresoxim-methyl suspending agent), example of formulations 3(60% benzene metsulfovax SSF 126 water dispersible granules), example of formulations 10(49% benzene metsulfovax fluoxastrobin wetting powder), example of formulations 5(40% benzene metsulfovax ZEN 90160 water dispersible granules), example of formulations 18(30% benzene metsulfovax SYP-3375 suspending agent) control rice blast field trial verifies that these several medicaments are to the control efficiency of rice blast and to the safety of paddy rice.Trial crops is paddy rice, and controlling object is rice blast (Pyricularia oryzae Cav.).Test is located at the Hanzhong City Chenggu County, and test medicine and dosage see table 6 for details.Other establishes contrast medicament and blank, and every processing repeats for 4 times, every residential quarter area 30 ㎡, and totally 56 residential quarters, district's group is arranged at random.Adopt conventional spray-on process, mu dispenser liquid 50kg evenly sprays the paddy rice complete stool.Altogether dispenser is 2 times, paddy rice booting latter stage and each dispenser of full heading time 1 time.
Investigation and statistical method:
Investigation in 14 days after the 2nd dispenser, investigation method is 5 samplings in every residential quarter, every some investigation 50 fringes, grade scale is as follows:
0 grade: anosis;
1 grade: every fringe loss is (morbidity of indivedual branch stalk) below 5%;
3 grades: every fringe loss 6%-20% (branch stalk morbidity about 1/3);
5 grades: every fringe loss 21%-50% (fringe neck or main shaft morbidity, grain half is flat);
7 grades: every fringe loss 51%-70% (morbidity of fringe neck, most of shrivelled kernel);
9 grades: every fringe loss 71%-100% (morbidity of fringe neck causes dead ears).
Refer to calculate preventive effect according to disease.Behind each spray medicine behind the 1st day and the medicine some days, each processed impact on paddy rice to observe medicament.
Disease index=[Σ (sick spike numbers at different levels * relative level numerical value)/investigate total spike number * 9] * 100%
Control efficiency (%)=[(contrast disease index-processing disease index)/contrast disease index] * 100.
Field test results shows: 63% benzene metsulfovax azoxystrobin water dispersible granule, 45% benzene metsulfovax kresoxim-methyl suspending agent, 60% benzene metsulfovax SSF 126 water dispersible granules, 49% benzene metsulfovax fluoxastrobin wetting powder, 40% benzene metsulfovax ZEN 90160 water dispersible granules, per 667 ㎡ of 30% benzene metsulfovax SYP-3375 suspending agent press respectively 15g, 20g, 15g, 20g, 30g, the 20g consumption, 14 days preventive effects to rice blast are respectively 88.67% behind second time medicine, 86.85%, 92.97%, 83.62%, 85.55%, 90.09%, obviously be better than per 667 ㎡ and use 10% benzene metsulfovax suspending agent 50g, 25% Fluoxastrobin suspending agent 50g, 25% kresoxim-methyl suspending agent 50g, 30% SSF 126 wetting powder 50g, 35 fluoxastrobin wetting powder 50g, 40% ZEN 90160 water dispersible granules 50g, 25% SYP-3375 suspending agent 40g is to the preventive effect of rice blast, and difference reaches utmost point significance level (table 6).
Experimental observation finds that mixed insecticide preparation also shows good control efficiency to rice sheath blight disease.
To the security survey of paddy rice, to observe in some days behind the 1st day and the medicine behind the spray medicine, each test is processed paddy rice is occured without the poisoning phenomenon.
After result of the test shows that benzene metsulfovax and Fluoxastrobin, kresoxim-methyl, SSF 126, fluoxastrobin, ZEN 90160, SYP-3375 are mixed, obviously improved the control efficiency to rice blast, and the rice sheath blight of can doublely harnessing the river, dosage and drug cost have been reduced, to paddy growth safety, it is the desirable medicament of control rice blast.
Claims (9)
1. bactericidal composition that contains the benzene metsulfovax is characterized in that the bactericidal composition active component is:
(1) first active component benzene metsulfovax;
(2) second active components are Fluoxastrobin, kresoxim-methyl, SSF 126, fluoxastrobin, ZEN 90160 or the SYP-3375 that is selected from methoxy acrylic bactericide;
The weight ratio of the first active component and the second active component is 1:10～8:1.
2. the described bactericidal composition that contains the benzene metsulfovax according to claim 1, it is characterized in that: the weight ratio of the first active component and the second active component is 1:8～5:1.
3. the described bactericidal composition that contains the benzene metsulfovax according to claim 2, it is characterized in that: the weight ratio of the first active component and the second active component is 1:5～2:1.
4. the described bactericidal composition that contains the benzene metsulfovax according to claim 3, it is characterized in that: the weight ratio of the first active component and the second active component is 1:2～1:1.
5. according to claim 1 to 4 one of any described bactericidal compositions that contain the benzene metsulfovax, it is characterized in that: the content sum of the first active component and the second active component is 5%～85% of described composition total weight.
6. the described bactericidal composition that contains the benzene metsulfovax according to claim 5, it is characterized in that: the content sum of the first active component and the second active component is 10%～75% of described composition total weight.
7. the described bactericidal composition that contains the benzene metsulfovax according to claim 5, it is characterized in that: described combination dosage form is water dispersible granules, wetting powder, suspending agent.
8. one of any described application of bactericidal composition in control crops downy mildew, powdery mildew, rice blast, banded sclerotial blight that contains the benzene metsulfovax of claim 1 to 4.
9. according to claim 8 described application is characterized in that described downy mildew is cucumber downy mildew, downy mildew of garpe, and powdery mildew is powdery mildew of cucumber, and rice blast is rice blast, and banded sclerotial blight is rice sheath blight disease.
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103392716A (en) * | 2013-06-30 | 2013-11-20 | 广东中迅农科股份有限公司 | Bactericidal composition containing benthiavalicarb isopropyl and azoxystrobin |
| CN103444734A (en) * | 2013-09-04 | 2013-12-18 | 利尔化学股份有限公司 | Bactericidal composition containing benthiavalicarb-isopropyl and azoxystrobin and application thereof |
| CN105076141A (en) * | 2014-11-17 | 2015-11-25 | 吉林省八达农药有限公司 | Composition containing coumoxystrobin and related bactericide |
| CN106342833A (en) * | 2016-08-29 | 2017-01-25 | 田文华 | Sterilized composition containing fluoxastrobin and cnidium lactone |
| CN108669084A (en) * | 2018-08-24 | 2018-10-19 | 江西禾益化工股份有限公司 | A kind of bactericidal composition containing benzene metsulfovax and chlorine nalidixic bacterium ester and its application |
| CN108935497A (en) * | 2018-08-23 | 2018-12-07 | 江西禾益化工股份有限公司 | A kind of bactericidal composition containing containing benzene metsulfovax and alkene oxime amine and its application |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101406191A (en) * | 2007-10-09 | 2009-04-15 | 中国中化集团公司 | Fungicidal compositions |
| CN101637157A (en) * | 2008-07-30 | 2010-02-03 | 中国中化集团公司 | Fungicide composition |
| WO2010046387A2 (en) * | 2008-10-21 | 2010-04-29 | Basf Se | Use of a respiration complex iii inhibitor on cultivated plants |
| CN101822263A (en) * | 2010-01-27 | 2010-09-08 | 深圳诺普信农化股份有限公司 | Sterilization compound containing ZJ0712 |
-
2013
- 2013-02-04 CN CN201310041361.6A patent/CN103053561B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101406191A (en) * | 2007-10-09 | 2009-04-15 | 中国中化集团公司 | Fungicidal compositions |
| CN101637157A (en) * | 2008-07-30 | 2010-02-03 | 中国中化集团公司 | Fungicide composition |
| WO2010046387A2 (en) * | 2008-10-21 | 2010-04-29 | Basf Se | Use of a respiration complex iii inhibitor on cultivated plants |
| CN101822263A (en) * | 2010-01-27 | 2010-09-08 | 深圳诺普信农化股份有限公司 | Sterilization compound containing ZJ0712 |
Non-Patent Citations (1)
| Title |
|---|
| 骆焱平 等: "甲氧丙烯酸酯类杀菌剂的研究进展", 《中国科技论文在线》 * |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103392716A (en) * | 2013-06-30 | 2013-11-20 | 广东中迅农科股份有限公司 | Bactericidal composition containing benthiavalicarb isopropyl and azoxystrobin |
| CN103444734A (en) * | 2013-09-04 | 2013-12-18 | 利尔化学股份有限公司 | Bactericidal composition containing benthiavalicarb-isopropyl and azoxystrobin and application thereof |
| CN105076141A (en) * | 2014-11-17 | 2015-11-25 | 吉林省八达农药有限公司 | Composition containing coumoxystrobin and related bactericide |
| CN106342833A (en) * | 2016-08-29 | 2017-01-25 | 田文华 | Sterilized composition containing fluoxastrobin and cnidium lactone |
| CN106342833B (en) * | 2016-08-29 | 2018-11-30 | 东阳市天齐知识产权运营有限公司 | A kind of bactericidal composition containing fluoxastrobin and Osthole |
| CN108935497A (en) * | 2018-08-23 | 2018-12-07 | 江西禾益化工股份有限公司 | A kind of bactericidal composition containing containing benzene metsulfovax and alkene oxime amine and its application |
| CN108669084A (en) * | 2018-08-24 | 2018-10-19 | 江西禾益化工股份有限公司 | A kind of bactericidal composition containing benzene metsulfovax and chlorine nalidixic bacterium ester and its application |
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