CN108669084A - A kind of bactericidal composition containing benzene metsulfovax and chlorine nalidixic bacterium ester and its application - Google Patents
A kind of bactericidal composition containing benzene metsulfovax and chlorine nalidixic bacterium ester and its application Download PDFInfo
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- CN108669084A CN108669084A CN201810969407.3A CN201810969407A CN108669084A CN 108669084 A CN108669084 A CN 108669084A CN 201810969407 A CN201810969407 A CN 201810969407A CN 108669084 A CN108669084 A CN 108669084A
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
- A01N47/10—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof
- A01N47/24—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof containing the groups, or; Thio analogues thereof
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
- A01N47/10—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof
- A01N47/12—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof containing a —O—CO—N< group, or a thio analogue thereof, neither directly attached to a ring nor the nitrogen atom being a member of a heterocyclic ring
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Abstract
The invention discloses a kind of bactericidal composition containing benzene metsulfovax and chlorine nalidixic bacterium ester, active ingredient are benzene metsulfovax and chlorine nalidixic bacterium ester, and the mass ratio of benzene metsulfovax and chlorine nalidixic bacterium ester is 50:1‑1:50.The bactericidal composition of the present invention has good synergistic effect in range on one point, and control effect significantly improves compared with single dose；Field dosage can be greatly decreased, reduce production and application cost, reduce pesticide residue, be conducive to the sustainable development of environment；The mechanism of action of active ingredient is different in bactericidal composition, is conducive to the generation for avoiding or delaying disease drug resistance；Expand prevention spectrum, while preventing crop downy mildew, late blight and powdery mildew, virosis can be prevented.
Description
Technical field
The present invention relates to bactericidal composition technical field, specially a kind of sterilization group containing benzene metsulfovax and chlorine nalidixic bacterium ester
Close object and its application.
Background technology
Benzene metsulfovax, English name：Benthiavalicarb-isopropyl, chemical name：[[(6- fluoro benzothiazoles-
2- yls)-ethylaminocarbonyl] -2- methyl-propyls] carbamic acid isopropyl ester.Benzene metsulfovax are by Japanese combinatorial chemistry company
The new type bactericide developed jointly in 1992 with Ihara companies, active site is substitution fluorine atom and amino acid on phenyl ring
Peptide structure, the compound have it is very highly selective, the late blight and downy mildew mainly caused by Oomycete germ to crop has
Good prevention effect and therapeutic activity.
Chlorine nalidixic bacterium ester, chemical name：N- methoxyl groups-N- [2- [[(3,5,6- trichloropyridine -2- bases) oxygen] methyl] phenyl]
Methyl carbamate.Chlorine nalidixic bacterium ester is the methoxy acrylic acid with independent intellectual property right that Shenyang Chemical Engineering Inst develops
Esters fungicide is a kind of high-efficiency broad spectrum low toxicity fungicide, has preventive and therapeutic action, to by sac fungus, basidiomycetes and half
Know microbial wheat powdery mildew, rice blast, false smut, cucurbits powdery mildew, tomato powdery mildew, rust of apple (Gymnosporangium yamadai), watermelon anthrax,
The multiple diseases such as flowers powdery mildew show excellent control effect；Go out in variable rate technology and excellent prevents, treats and root out work
With.
In recent years, due to single drug and unscientific application method, lead to many kinds of pathogens such as powdery mildew, downy mildew
Bacterium etc. produces resistance to many currently used pesticides, and drug resistance is increasingly severe, while formulation rate after resistance generation
With the increase of spraying times, not only cost accounting is made to increase, and aggravated environmental pollution, become chemical prevention one is big
Problem.Therefore, it is badly in need of microbicide compositions efficiently, environmentally friendly, less toxic.The mechanism of action of benzene metsulfovax and chlorine nalidixic bacterium ester fungicide
Difference mutually compounds and expands fungicidal spectrum in range on one point, improves the bactericidal effect of fungicide, avoid or delay disease drug resistance
Generation, be conducive to the integrated control of crop disease.In conclusion Bactericidal composite of the exploitation containing benzene metsulfovax and chlorine nalidixic bacterium ester
Object is of great significance.
Invention content
It is suitble to agriculturally produce and use the purpose of the present invention is to provide a kind of, high-efficiency environment friendly, wide spectrum and contributes to
Dosage is reduced, delays pathogen to generate resistance and reduces the bactericidal composition of use cost.
A kind of bactericidal composition containing benzene metsulfovax and chlorine nalidixic bacterium ester, active ingredient are benzene metsulfovax and chlorine pyridine bacterium
The mass ratio of ester, benzene metsulfovax and chlorine nalidixic bacterium ester is 50:1-1:50.
Preferably, the mass ratio of active ingredient benzene metsulfovax and chlorine nalidixic bacterium ester is 20:1-1:20.
Preferably, active ingredient benzene metsulfovax and gross mass percentage composition of the chlorine nalidixic bacterium ester in bactericidal composition are 1%-
90%。
Preferably, by selecting different adjuvants, the dosage form of the bactericidal composition can be suspending agent, wettable powder
Agent, water dispersible granules, microemulsion, aqueous emulsion, granule and suspension seed-coating agent.
The present invention also provides a kind of application of the bactericidal composition containing benzene metsulfovax and chlorine nalidixic bacterium ester, the sterilization groups
It closes object to be used to prevent the plurality of plant diseases on the crops such as vegetables, melon and fruit, is particularly suitable for prevention downy mildew, late blight and white powder
Disease.
Compared with prior art, the beneficial effects of the invention are as follows：
1, bactericidal composition of the invention has good synergistic effect in range on one point, and control effect obviously carries compared with single dose
It is high；
2, field dosage can be greatly decreased, reduce production and application cost, reduce pesticide residue, be conducive to environment
Sustainable development；
3, the mechanism of action of active ingredient is different in bactericidal composition, is conducive to the generation for avoiding or delaying disease drug resistance；
4, expand prevention spectrum, while preventing crop downy mildew, late blight and powdery mildew, virosis can be prevented.
Specific implementation mode
In order to make the purpose , technical scheme and advantage of the present invention be clearer, below in conjunction with specific embodiment, to this
Invention is further elaborated.It should be appreciated that the specific embodiments described herein are merely illustrative of the present invention, not
For limiting the present invention.
Different pesticide active ingredients is compounded, is drug effect and resistance etc. in current solution pesticide single dose application process
A kind of effective means of problem.After different pesticide active ingredients is compounded, three kinds of type of action are typically exhibited, that is, is added and makees
With, synergistic effect and antagonism, but it is specially which kind of effect, it is unpredictable, only just it can know that by a large number of experiments.Compounding
Synergy is formulated well, can be improved practical control effect, be reduced the usage amount of pesticide, contribute to the generation of delaying drug resistance, be section
Learn the important means of controlling disease.
Bactericidal composition of the present invention with bactericidal composition of the present invention with benzene metsulfovax be a kind of active ingredient, with chlorine nalidixic bacterium ester
For another active ingredient, the combination between them has obvious synergistic function downy mildew, late blight and powdery mildew,
Rather than just the simple addition of two kinds of drug actions, specifically it is illustrated with following bioassay example.
The indoor toxicity determination test of Assays Example 1, benzene metsulfovax and chlorine nalidixic bacterium ester compounding to cucumber downy mildew
Subjects：Cucumber downy mildew germ
This experiment use pot-culture method, with writing brush dip 10 DEG C or so distillation washing under pick up from artificial climate room carry downy mildew
The sporangium at the cucumber leaves back side of germ, is made into 2.0-3 × 105The suspension of a sporangium/mL.Choose two of growing way unanimously
Piece leaf period cucumber seedling, each processing select 5 basins for trying melon seedling, are sprayed under 50PSI pressure with Potter spray towers, each located
Manage about 5mL.5 concentration gradients are arranged in each medicament, to spray equivalent clear water as blank control.Chemicals treatment is sprayed afterwards for 24 hours
Mist is inoculated with bacterium of downy mildew of cucumber sporangia suspension, and cucumber seedling is placed in growth cabinet after inoculation（Relative humidity 100%, temperature
15-20 DEG C of degree）Culture, keeps 16-24 DEG C of temperature, 90% or so moisturizing of relative humidity to induce afterwards for 24 hours, and the state of an illness is investigated after 5 days and is referred to
Number, and calculate control effect.
Grade scale
0 grade：Blade disease-free spot；
1 grade：Lesion area accounts for 5% or less full wafer leaf area；
3 grades：Lesion area accounts for the 6%-10% of full wafer leaf area；
5 grades：Lesion area accounts for the 11%-25% of full wafer leaf area；
7 grades：Lesion area accounts for the 26%-50% of full wafer leaf area；
9 grades：Lesion area accounts for 50% or more full wafer leaf area.
Drug effect computational methods：
Disease index (%)=
Control effect (%)=
Control effect is converted into niqueMin (y), and liquor strength (μ g/mL) is converted into logarithm (x), and poison is calculated with least square method
Concentration EC in power equation and inhibition50, the toxicity index and co-toxicity coefficient (CTC) of medicament are calculated according to Sun Yunpei's Method.
Survey toxicity index (ATI)=(standard agent EC50/ reagent agent EC50)×100
B in percentage composition+B medicament toxicity index × mixture of A in theoretical toxicity index (TTI)=A medicament toxicity index × mixture
Percentage composition
Co-toxicity coefficient (CTI)=[mixture surveys toxicity index (ATI)/mixtures theoretical toxicity index (TTI)] × 100
When CTC≤80, then composition shows as antagonism, when 80<CTC<120, then composition show as summation action, when
CTC >=120, then composition show as synergistic effect.
1 benzene metsulfovax of table compound the The Toxicity Determination result to cucumber downy mildew with chlorine nalidixic bacterium ester
Test result shows benzene metsulfovax and chlorine nalidixic bacterium ester compounding prevention cucumber downy mildew, matches 50:1-1:When between 50,
Co-toxicity coefficient all 120.0 or more, has certain synergistic effect, and matches 10:1-1:When between 10, co-toxicity coefficient is high
In 200.0, synergistic effect becomes apparent from.
The indoor toxicity determination test of Assays Example 2, benzene metsulfovax and chlorine nalidixic bacterium ester compounding to tomato late blight.
Subjects：Tomato late blight germ
This experiment uses pot-culture method.When tomato potting grows to 2-4 leaf periods, number is spare.Experiment is existed with pathogen
It is cultivated on suitable culture medium, after sporangium to be generated, sporangium is washed down with sterile water, is filtered with double gauze, it is made 1 ×
105The suspension of a sporangium/mL.According to agent activity, 5-7 series mass concentration is set.Liquid is uniformly sprayed on leaf
Wait for that liquid natural air drying is spare to whole wettings in face.Often handle 3 basins, 4 repetitions, and set containing only solvent and surfactant and
Blank control is made in processing without active ingredient.Chemicals treatment for 24 hours after, with crops sprayer on tomato leaf uniformly sprinkling connect
Kind.After inoculation, cultivated 7 days under conditions of 18-20 DEG C of temperature, 90% or more relative humidity.Count the disease on every plant of tomato leaf
Spot area, investigation prevention effect.Often handling at least 30 leaves of investigation, stage division is：
0 grade：Blade disease-free spot；
1 grade：Only a small amount of small scab, lesion area account for 10% or less full wafer leaf area on blade；
3 grades：Lesion area accounts for the 10%-25% of full wafer leaf area on blade；
5 grades：Lesion area accounts for the 26%-50% of full wafer leaf area on blade；
7 grades：Lesion area accounts for 50% or more of full wafer leaf area on blade；
9 grades：Full leaf morbidity is withered.
Drug effect calculating, toxicity index and co-toxicity coefficient（CTC）It calculates, analysis method is same as above.
The Toxicity Determination result is referring to table 2
2 benzene metsulfovax of table compound the The Toxicity Determination result to tomato late blight with chlorine nalidixic bacterium ester
Test result shows benzene metsulfovax and chlorine nalidixic bacterium ester compounding prevention tomato late blight, matches 50:1-1:When between 50,
Co-toxicity coefficient all 120.0 or more, has certain synergistic effect, and matches 10:1-1:When between 10, co-toxicity coefficient is high
In 200.0, synergistic effect becomes apparent from.
Assays Example 3, benzene metsulfovax and chlorine nalidixic bacterium ester compounding try the Toxicity Determination of cucumber powdery mildew's pathogen
It tests
Subjects：Cucumber powdery mildew's pathogen
This experiment uses pot-culture method.Potting grows to 4-5 piece true leaves, and number is spare.By interior generation for 24 hours on cucumber leaves of falling ill
Powdery Mildew Fresh spores are uniformly shaken off to be inoculated on examination cucumber seedling.According to agent activity, 5-7 series mass of setting is dense
Degree.After inoculation 24 hours, liquid is uniformly sprayed on to blade face to whole wettings, waits for that liquid natural air drying is spare.Often handle 3 basins, 4
Secondary repetition, and set containing only solvent and surfactant and make blank control without containing the processing for imitating ingredient.Examination material after inoculation moves
Into growth cabinet（Relative humidity 100%, 20 ± 2 DEG C of temperature）Culture 7 days.Lesion area on the every basin cucumber leaves of statistics,
Disease index is investigated, and calculates control effect.
Grade scale
0 grade：Blade disease-free spot；
1 grade：Lesion area accounts for 5% or less full wafer leaf area；
3 grades：Lesion area accounts for the 6%-15% of full wafer leaf area；
5 grades：Lesion area accounts for the 16%-25% of full wafer leaf area；
7 grades：Lesion area accounts for the 26%-50% of full wafer leaf area；
9 grades：Lesion area accounts for 50% or more full wafer leaf area.
Drug effect calculating, toxicity index and co-toxicity coefficient（CTC）It calculates, analysis method is same as above.
The Toxicity Determination result is referring to table 3
3 benzene metsulfovax of table compound the The Toxicity Determination result to cucumber powdery mildew's pathogen with chlorine nalidixic bacterium ester
Test result shows benzene metsulfovax and chlorine nalidixic bacterium ester compounding prevention cucumber powdery mildew's pathogen, matches 50:1-1:Between 50
When, co-toxicity coefficient all 120.0 or more, has certain synergistic effect, and matches 10:1-1:When between 10, co-toxicity coefficient
200.0 are above, synergistic effect becomes apparent from.
The above measurement result shows benzene metsulfovax and a kind of compounding prevention cucumber downy mildew, Phytophthora infestans in chlorine nalidixic bacterium ester
The proportioning of disease and powdery mildew of cucumber is 50:1-1:When between 50, co-toxicity coefficient all 120.0 or more, there is certain synergy to make
With, and match 10:1-1:When between 10,200.0 or more, synergistic effect becomes apparent from co-toxicity coefficient.
Combination sterilization composition of the present invention can be prepared into suspending agent, the wettable of suitable agricultural use by known method
Pulvis, water dispersible granules, microemulsion, aqueous emulsion, granule and suspension seed-coating agent.It is illustrated, is matched with specific embodiment below
Percentage is mass percent in side, and benzene metsulfovax active compound effective content is 95%, chlorine nalidixic bacterium ester active compound effective content is 95%,
Effective content folding hundred is pressed when use to calculate, and is not being repeated below.
Suspending agent embodiment
By each components such as pesticide active ingredient, dispersant, wetting agent, thickener, antifoaming agent, antifreezing agent and water in the ratio of formula
It is uniformly mixed, half product is obtained after sand mill wet method sand milling, mend to be mixed with water after analysis and filter up to suspending agent.
Embodiment 1:22% benzene metsulfovax chlorine nalidixic bacterium ester suspending agent
Benzene metsulfovax 20%, chlorine nalidixic bacterium ester 2%, ethylene glycol（Antifreezing agent）5%, pull open powder（Wetting agent）1.5%, sodium lignin sulfonate
（Dispersant）3%, xanthans（Thickener）0.15%, aluminium-magnesium silicate（Thickener）0.5%, sodium benzoate（Preservative）0.2%, organic
Silicon defoaming agent（Antifoaming agent）0.1%, deionized water polishing is to 100%.
Embodiment 2:32% benzene metsulfovax chlorine nalidixic bacterium ester suspending agent
Benzene metsulfovax 2%, chlorine nalidixic bacterium ester 30%, ethylene glycol（Antifreezing agent）5%, pull open powder（Wetting agent）2%, sodium lignin sulfonate
（Dispersant）3%, xanthans（Thickener）0.1%, aluminium-magnesium silicate（Thickener）0.5%, sodium benzoate（Preservative）0.2%, organic
Silicon defoaming agent（Antifoaming agent）0.1%, deionized water polishing is to 100%.
Embodiment 3:40% benzene metsulfovax chlorine nalidixic bacterium ester suspending agent
Benzene metsulfovax 20%, chlorine nalidixic bacterium ester 20%, ethylene glycol（Antifreezing agent）5%, pull open powder（Wetting agent）1.5%, polycarboxylate（Point
Powder）2%, sodium lignin sulfonate（Dispersant）2%, xanthans（Thickener）0.1%, sodium benzoate（Preservative）0.2%, organosilicon
Antifoaming agent（Antifoaming agent）0.1%, deionized water polishing is to 100%.
Wettable powder embodiment
Pesticide active ingredient, auxiliary agent and filler are mixed according to the formula uniformly, remix to obtain after air-flow crushing wettable
Property pulvis.
Embodiment 4:50% benzene metsulfovax chlorine nalidixic bacterium ester wettable powder
Benzene metsulfovax 20%, chlorine nalidixic bacterium ester 30%, lauryl sodium sulfate（Wetting agent）2%, Negel（Dispersant）
3%, sodium lignin sulfonate（Dispersant）5%, white carbon（Filler）5%, kaolin（Filler）Polishing is to 100%.
Embodiment 5:90% benzene metsulfovax chlorine nalidixic bacterium ester wettable powder
Benzene metsulfovax 60%, chlorine nalidixic bacterium ester 30%, Negel（Dispersant）1%, sodium lignin sulfonate（Dispersant）1%、
Polycarboxylate（Dispersant）2%, kaolin（Filler）Polishing is to 100%.
Embodiment 6:25% benzene metsulfovax chlorine nalidixic bacterium ester wettable powder
Benzene metsulfovax 15%, chlorine nalidixic bacterium ester 10%, lauryl sodium sulfate（Wetting agent）1%, Negel（Dispersant）
2%, white carbon（Filler）5%, kaolin（Filler）Polishing is to 100%.
Water dispersible granules embodiment
Pesticide active ingredient, auxiliary agent and filler are mixed according to the formula uniformly, wettable powder is obtained after air-flow crushing, then
A certain amount of water is added, water dispersible granules are made through kneading, granulation, drying, screening.
Embodiment 7:20% benzene metsulfovax chlorine nalidixic bacterium ester water dispersible granules
Benzene metsulfovax 15%, chlorine nalidixic bacterium ester 5%, lauryl sodium sulfate（Wetting agent）2%, Negel（Dispersant）3%、
Sodium lignin sulfonate（Dispersant）4%, polycarboxylate（Dispersant）1%, ammonium sulfate（Disintegrant）20%, kaolin（Filler）Polishing
To 100%.
Embodiment 8:45% benzene metsulfovax chlorine nalidixic bacterium ester water dispersible granules
Benzene metsulfovax 15%, chlorine nalidixic bacterium ester 30%, lauryl sodium sulfate（Wetting agent）4%, sodium lignin sulfonate（Dispersant）
7%, Negel（Dispersant）3%, polycarboxylate（Dispersant）1%, ammonium sulfate（Disintegrant）5%, kaolin（Filler）It mends
Together to 100%.
Embodiment 9:80% benzene metsulfovax chlorine nalidixic bacterium ester water dispersible granules
Benzene metsulfovax 40%, chlorine nalidixic bacterium ester 40%, lauryl sodium sulfate（Wetting agent）2%, Negel（Dispersant）
4%, sodium lignin sulfonate（Dispersant）5%, polycarboxylate（Dispersant）2%, ammonium sulfate（Filler）Polishing is to 100%.
Microemulsion embodiment
Pesticide active ingredient is dissolved in solvent and cosolvent, surfactant is added, is uniformly mixed and obtains microemulsion.
Embodiment 10:30% benzene metsulfovax chlorine nalidixic bacterium ester microemulsion
Benzene metsulfovax 20%, chlorine nalidixic bacterium ester 10%, N-Methyl pyrrolidone（Solvent）4%, phenethyl phenol polyoxyethylene method（Emulsification
Agent）6%, calcium dodecyl benzene sulfonate（Emulsifier）4%, castor oil polyoxyethylene ether（Emulsifier）6%, deionized water polishing is extremely
100%。
Aqueous emulsion embodiment
Pesticide active ingredient is dissolved in solvent and cosolvent, surfactant is added, is uniformly mixed and obtains oil phase；It will be water-soluble
During the property components such as component and deionized water are mixed to prepare water phase, then the oil phase is added to the aqueous phase, stirring while adding, high speed shear is allowed to
Aqueous emulsion is obtained as uniform emulsion.
Embodiment 11:25% benzene metsulfovax chlorine nalidixic bacterium ester aqueous emulsion
Benzene metsulfovax 10%, chlorine nalidixic bacterium ester 15%, ethylene glycol（Antifreezing agent）5%, N-Methyl pyrrolidone（Solvent）4%, cyclohexanone
（Solvent）9%, phenethyl phenol polyoxyethylene method（Emulsifier）7%, calcium dodecyl benzene sulfonate（Emulsifier）5%, deionized water polishing
To 100%.
Granule embodiment
Embodiment 12:1% benzene metsulfovax chlorine nalidixic bacterium ester granule
Benzene metsulfovax 0.5%, chlorine nalidixic bacterium ester 0.5%, fatty alcohol polyoxyethylene ether（Emulsifier）1%, N-Methyl pyrrolidone（It is molten
Agent）2%, white carbon（Adsorbent）2%, brick slag（Carrier）Polishing is to 100%.
Suspension seed-coating agent embodiment
By each components such as pesticide active ingredient, dispersant, wetting agent, thickener, antifoaming agent, antifreezing agent and water in the ratio of formula
It is uniformly mixed, half product is obtained after sand mill wet method sand milling, water, film forming agent and colorant are added after analysis and is uniformly mixed filtering
Up to suspension seed-coating agent.
Embodiment 13:10.5% benzene metsulfovax chlorine nalidixic bacterium ester suspension seed-coating agent
Benzene metsulfovax 0.5%, chlorine nalidixic bacterium ester 10%, ethylene glycol（Antifreezing agent）5%, sodium methylene bis-naphthalene sulfonate（Wetting agent）1%, wooden
Quality sodium sulfonate（Dispersant）3%, polycarboxylate（Dispersant）1%, xanthans（Thickener）0.15%, aluminium-magnesium silicate（Thickener）
1%, polyvinyl alcohol（PVA）(film forming agent) 0.5%, solvent red（HRR）（Colorant）2%, sodium benzoate（Preservative）0.2%, organic
Silicon defoaming agent（Antifoaming agent）0.1%, deionized water polishing is to 100%.
In order to further illustrate the present invention the advantages of technical formula scheme, present invention field trial embodiment in detail below
It is illustrated.
Field information example 1：Benzene metsulfovax compound the field control effectiveness test to powdery mildew of cucumber with chlorine nalidixic bacterium ester
Subjects：Powdery mildew of cucumber
Test medicine and dosage are shown in Table 4, often handle 4 cells and repeat, 20 square metres of each plot area.In the early stages of disease
Carry out first time dispenser, even spraying is sprayed onto until blade drips, using clear water processing as blank control.It is applied after 7 days second
Medicine.The incidence of 7 days investigation powderys mildew of cucumber before first time medicine and after second of medicine.Each cell is sampled using 5 points,
Every is investigated two plants, and every plant of all blades of investigation account for the percentage of entire leaf area with lesion area and recorded to be classified.It calculates each
Handle disease index and control effect.Grade scale：
0 grade：Disease-free spot；
1 grade：Lesion area accounts for 5% or less entire leaf area；
3 grades：Lesion area accounts for the 6%-15% of entire leaf area；
5 grades：Lesion area accounts for the 16%-25% of entire leaf area；
7 grades：Lesion area accounts for the 26%-50% of entire leaf area；
9 grades：Lesion area accounts for 50% or more entire leaf area；
Drug effect computational methods：
Disease index=
Control effect（%）=
Field test results are shown in Table 4
4 benzene metsulfovax of table compound the field test results to powdery mildew of cucumber with chlorine nalidixic bacterium ester
As can be seen that benzene metsulfovax, chlorine nalidixic bacterium ester single dose are respectively to the preventive effect of powdery mildew of cucumber from 4 test result of table
76.21%, 73.51%, and bactericidal composition of the embodiment of the present invention is significantly increased in preventive effect, minimum preventive effect is 88.08%,
It has been up to 92.45%.The result of field trial fully shows after benzene metsulfovax and chlorine nalidixic bacterium ester compounding to powdery mildew of cucumber
With significant synergistic function, in the case where mu effective ingredient consumption is reduced compared with single dose, control effect greatly improves.Cause
This, the present composition has the beneficial effect for reducing cost, delaying drug resistance, reduction spraying times and pesticide residue
The foregoing is only a preferred embodiment of the present invention, but scope of protection of the present invention is not limited thereto, and it is any
Those familiar with the art in the technical scope disclosed by the present invention, according to the technique and scheme of the present invention and its invents
Design is subject to equivalent substitution or change, should be covered by the protection scope of the present invention.
Claims (5)
1. a kind of bactericidal composition containing benzene metsulfovax and chlorine nalidixic bacterium ester, it is characterised in that：Its active ingredient is benzene metsulfovax
With chlorine nalidixic bacterium ester, the mass ratio of benzene metsulfovax and chlorine nalidixic bacterium ester is 50:1-1:50.
2. bactericidal composition according to claim 1, it is characterised in that：The matter of active ingredient benzene metsulfovax and chlorine nalidixic bacterium ester
Amount ratio is 20:1-1:20.
3. a kind of bactericidal composition containing benzene metsulfovax and chlorine nalidixic bacterium ester according to claim 1, it is characterised in that：Have
It is 1%-90% that ingredient benzene metsulfovax, which are imitated, with gross mass percentage composition of the chlorine nalidixic bacterium ester in bactericidal composition.
4. a kind of bactericidal composition containing benzene metsulfovax and chlorine nalidixic bacterium ester according to claim 3, it is characterised in that：It is logical
It crosses and selects different adjuvants, the dosage form of the bactericidal composition can be suspending agent, wettable powder, water dispersible granules, micro-
Emulsion, aqueous emulsion, granule and suspension seed-coating agent.
5. a kind of application of the bactericidal composition according to claim 1 containing benzene metsulfovax and chlorine nalidixic bacterium ester, feature
It is：The bactericidal composition is used to prevent the plurality of plant diseases on the crops such as vegetables, melon and fruit, is particularly suitable for prevention downy mildew
Disease, late blight and powdery mildew.
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