CN108782578A - Composition pesticide containing folpet and fluorine azoles bacterium aniline - Google Patents
Composition pesticide containing folpet and fluorine azoles bacterium aniline Download PDFInfo
- Publication number
- CN108782578A CN108782578A CN201710310374.7A CN201710310374A CN108782578A CN 108782578 A CN108782578 A CN 108782578A CN 201710310374 A CN201710310374 A CN 201710310374A CN 108782578 A CN108782578 A CN 108782578A
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- China
- Prior art keywords
- folpet
- fluorine azoles
- azoles bacterium
- microbicide compositions
- bacterium aniline
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/02—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having no bond to a nitrogen atom
- A01N47/04—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having no bond to a nitrogen atom containing >N—S—C≡(Hal)3 groups
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/56—1,2-Diazoles; Hydrogenated 1,2-diazoles
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- Life Sciences & Earth Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention discloses a kind of microbicide compositions containing folpet and fluorine azoles bacterium aniline, the folpet of show activity ingredient and the weight ratio of fluorine azoles bacterium aniline are 1 in affiliated bactericidal composition:80~80:1, further preferred weight ratio is 1:20~20:1, it is still more preferably 5:1.The present composition can prepare several formulations type, any one in water dispersible granules, missible oil, suspending agent, wettable powder, suspension seed-coating agent etc..Compared with single dose, microbicide compositions of the invention compounding has notable synergistic effect, and the lasting period is long, can effectively reduce drug cost, improves drug effect.
Description
Technical field
The invention belongs to technical field of pesticide combination, it relates in particular to be a kind of to contain folpet and fluorine azoles bacterium benzene
The composition pesticide of amine, the composition pesticide are suitable for prevention multiple kinds of crops disease.
Background technology
Folpet（folpet）, Chinese nickname has Folpat, a Fu Erpei, No. CAS：133-07-3, chemical name：N- trichlorines
Methyl mercapto phthalimide, molecular formula：C9H4Cl3NO2S.Structural formula：
。
Folpet is broad spectrum protection organosulfureous fungicide, and it is a variety of mainly to prevent grain and oil crop, vegetables, fruit tree, flowers etc.
Disease has stimulation to growth and development of plants, can prevent rice blast, rice sheath blight disease, wheat rust, head blight, rape frost
Mildew, leaf spot of peanut, the late blight of potato, tomato early blight, anthracnose of tobacco, the various crops disease such as apple anthracnose,
And to crop safety.
Fluorine azoles bacterium aniline,（penflufen）, No. CAS：494793-67-8, molecular formula：C18H24FN3O.Chemical name：2 '-
The fluoro- 1,3- dimethyl pyrazoles -4- formailides of [(RS) -1,3- dimethylbutyls] -5-.Structural formula：
。
Fluorine azoles bacterium aniline is a kind of succinate dehydrogenase inhibitors, can prevent kind of a biography, the basidiomycetes and sac fungus that soil passes
Disease, main mechanism are worked on respiratory chain electron transmission Complex II, and correlation energy metabolism is blocked.Mainly there is silk
Disease caused by pyrenomycetes, black scurf of potato, wheat sharp eyespot, rice sheath blight disease, sclerotinia sclerotiorum etc., also wheat dissipate
Smut, the bunt of wheat, corn southern leaf blight etc..Treated, and seed can absorb fluorine azoles bacterium aniline in germination process,
It is transmitted to other positions of plant by xylem, plays the role of cover crop.
The simple pesticide single using mechanism of action, using effect are often restricted.Fluorine azoles bacterium aniline mechanism of action
Novelty, controlling disease effect is fine on the crop of part, but use scope is easy to be limited to, and folpet is protective fungicide,
Action site is more, and drug resistance is not likely to produce, and notable to multiple diseases preventive effect.Therefore it is a kind of reasonably to select complex preparation
Wise, the economical and effective method using pesticide.Retrieval is studied by my company researcher, fluorine azoles bacterium aniline and is gone out at present
Bacterium pellet respectively has composition research with other parts product respectively, such as application No. is the patent of invention of CN201610480915, relates to
And the Bactericidal composite to fluorine azoles bacterium aniline and Metalaxyl-M；Application No. is the patented inventions of CN201610399399 to be related to fluorine azoles
The Bactericidal composite of bacterium aniline and pyraclostrobin；Application No. is the patented inventions of CN201510074857 to be related to fluorine azoles bacterium aniline
With the Bactericidal composite of thifluzamide；Application No. is the patents of invention of CN201510147932 to be related to killing for folpet and metconazole
Bacterium combines；Application No. is the antimicrobial combinations that the patent of invention of CN201610365548 is related to folpet and fluorine ether bacterium amide.
However, there has been no the antimicrobial combinations that folpet and fluorine azoles bacterium aniline compound for technology at present.The present invention sieves through a large number of experiments
Choosing confirms that, by the compounding of folpet and fluorine azoles bacterium aniline, prevention spectrum has obtained prodigious expansion, and synergistic effect is apparent, right
Delay drug resistance to play positive effect, to solve excessive pesticide residues, a series of problems, such as environmental pollution provide compared with
Good thinking.
Invention content
It is an object of the invention to the vacancy for the existing research and development technology in market, providing a kind of can effectively prevent phytopathy
Evil, have wider prevention spectrum, have and can notable synergistic antimicrobial combination.
Another object of the present invention is to provide the application of the microbicide compositions, the pesticide combination is particularly suitable for preventing
Control the multiple diseases of the crops such as potato, wheat, rice, rape, vegetables, fruit tree kind, including but not limited to sclerotinia sclerotiorum,
Wheat powdery mildew, rust, banded sclerotial blight, damping-off, smut, black scurf of potato, corn southern leaf blight, downy mildew of garpe, white rot
Disease, anthracnose, ring rot of apple, spot defoliation, anthracnose, brown spot, leaf muld of tomato etc..
The present invention is achieved by the following technical solutions：
A kind of pesticide bacteriostat composition containing folpet and fluorine azoles bacterium aniline, the folpet and fluorine azoles bacterium aniline of the composition
Weight ratio is 1:50~50:1.
Further, the folpet of the composition and the ratio of fluorine azoles bacterium aniline preferred weight are 1:20~20:1, further
Preferably 5:1.
Further, the content for the preparation active ingredient that preferred fungicide composition is done is 1-90%.
Further, preferably composite preparation, active ingredient ratio are 20 ~ 80%, remaining is in Pesticide formulation
Conventional auxiliary element.
Auxiliary agent belonging to the present invention includes emulsifier, spreader, wetting agent, dispersant, antifreezing agent, solvent, cosolvent, thickening
It is one or more in agent, antifoaming agent, disintegrant etc..
Further, microbicide compositions of the invention are prepared by a conventional method into dosage form and are suitble to agriculturally make
Any one dosage form, including but not limited to missible oil, wettable powder, water dispersible granules, suspending agent, suspension emulsion, aqueous emulsion.
Technical program of the present invention also lies in above-mentioned microbicide compositions answering on prevention fungal diseases of plants drug
With using with remarkable result especially in terms of the diseases such as Cereal, fruit tree, vegetable crop.
Compared with prior art, microbicide compositions of the present invention have the beneficial effect that：
1, folpet and fluorine azoles bacterium aniline used in the present invention, two kinds of active ingredient mechanisms of action are completely different, and mutual mixture will not
Mutual antagonism, opposite the two can be effectively synergistic;
2, the crop range on probation that than two kinds compositions of the present composition scope of application are used alone increases, and is suitble to and anti-Zhiduo County
The fungal disease of kind field crop such as Cereal, fruit tree, vegetables, especially to damping-off, sclerotiniose, with good prevention effect
Fruit.And it can effectively inhibit generation of the germ to single active ingredient drug resistance;
3, preparation process of the present invention is simple to operation, the use of low for equipment requirements, convenient big production and field crop.
Specific implementation mode
One, example of formulations
1, embodiment 1:44% folpet fluorine azoles bacterium aniline missible oil（10:1）
Folpet 40%
Fluorine azoles bacterium aniline 4%
Agriculture breast 020,1#8 6%
Cyclohexanone 15%
Prosene surplus
By folpet, fluorine azoles bacterium aniline and auxiliary agent is divided uniformly to mix by above-mentioned formula, you can be made of the present invention 44%
Missible oil.
2, embodiment 2:50% folpet fluorine azoles bacterium aniline suspending agent（4:1）
Folpet 40%
Fluorine azoles bacterium aniline 10%
Aliphatic acid polyethenoxy ether 2.5%
Alkyl phenol polyoxyethylene ether 6%
Xanthans 0.2%
Carboxymethyl cellulose 2%
Organosilicon 0.4%
Deionized water surplus
Folpet, fluorine azoles bacterium aniline and each host proportioning are sufficiently mixed uniformly by above-mentioned formula, made under sand mill effect
The suspending agent for being 50% at active ingredient percentage.
3, embodiment 3：40% folpet fluorine azoles bacterium aniline suspending agent（3:1）
Folpet 30%
Fluorine azoles bacterium aniline 10%
Phosphate ester sulfonate 4%
Polycarboxylate 5%
Xanthans 0.5%
Lauryl sodium sulfate 2%
Ethylene glycol 5%
Oleic acid 6%
Solvent naphtha 10%
Deionized water surplus
Folpet, fluorine azoles bacterium aniline and each auxiliary agent are sufficiently mixed uniformly by above-mentioned formula, are formed under sand mill effect
Imitate the suspending agent that percentage composition is 40%.
4, embodiment 4:42% folpet fluorine azoles bacterium aniline water dispersible granules（5:1）
Folpet 35%
Fluorine azoles bacterium aniline 7%
Sodium lignin sulfonate 6%
Polyvinyl alcohol 4%
Ammonium sulfate 8%
White carbon 10%
Kaolin surplus
Folpet, fluorine azoles bacterium aniline and each auxiliary agent are added by formula rate by above-mentioned formula and carry out air-flow powder after mixing
It is broken, after a small amount of deionized water be added be stirred well to and uniformly can be prepared by required water dispersible granules product after drying.
5, embodiment 5:44% folpet fluorine azoles bacterium aniline suspension seed-coating agent（10:1）
Folpet 40%
Fluorine azoles bacterium aniline 4%
Fulvic acid 2%
Polyvinyl acetate 3%
Sodium lignin sulfonate 5%
Alkyl phenol polyoxyethylene ether 6%
Xanthans 0.2%
Carboxymethyl cellulose 2%
Ethylene glycol 5%
Acid red 0.4%
Kathon CG 0.4%
Deionized water surplus
Folpet, fluorine azoles bacterium aniline and each auxiliary agent proportioning are sufficiently mixed uniformly by above-mentioned formula, active ingredient percentage is made
Than the suspension seed-coating agent for 44%.
Two, biological activity determination
1, subjects：Rice sheath blight disease；
2, test method：Using mycelial growth rate method, fluorine azoles bacterium aniline and folpet mother liquor are taken, liquid tablet is made into, per ware
About 10 mL, each drug concentration are arranged 3 repetitions, blank control are separately arranged（Add sterile water）.By cultured rice banded sclerotial blight
Disease draws mycelia block with the sterilization punchers of a diameter of 0.5 cm, is moved respectively on different culture medium flat plates, is cultivated at 28 DEG C
3 days, measure colony diameter（mm）, and bacteriostasis rate is calculated, the logarithm matter of niqueMin and series concentration by inhibiting inhibiting rate
The linear regression analysis of inspection finds out the EC of processing50, use co-toxicity coefficient（CTC）To evaluate, medicament is specific to the activity of germ to be calculated
Mode is as follows：
Survey toxicity index (ATI)=(standard agent EC50/ reagent agent EC50)×100
In theoretical toxicity index (TTI)=A medicament toxicity index × mixture in percentage composition+B medicament toxicity index × mixture of A
The percentage composition of B
Co-toxicity coefficient (CTC)=[mixture surveys toxicity index (ATI)/mixtures theoretical toxicity index (TTI)] × 100
As CTC < 80, then composition shows as antagonism, and as 80 < CTC < 120, then composition shows as summation action, when
CTC > 120, then composition show as synergistic effect.
Test result is as shown in table 1.
The Toxicity Determination result shows：Folpet and fluorine azoles bacterium aniline are with weight ratio for 1：50~50：1 is mixed to rice
Banded sclerotial blight has preferable virulence, weight ratio 1：20-20：1 synergistic effect is notable, and especially weight ratio is 5：1 synergistic effect is most
It is notable.
Three, field control effectiveness test
The composite preparation of 1-4 of the embodiment of the present invention is selected to carry out the field control effectiveness test of rice sheath blight disease to determine the present invention's
Composition pesticide is with 80% folpet water dispersible granules and 22% fluorine azoles bacterium aniline suspending agent to the control effect of rice sheath blight disease
Comparison medicament tests 4 repetitions of each processing setting, each plot area 20m2, share 20 cells, random district's groups arrangement.It adopts
Hand spray processing is carried out with conventional spray-on process, to plant cauline leaf even spraying, sprays complete stool.In rice sheath blight disease early stage
First time dispenser is carried out, second is carried out after 10 days and is sprayed, respectively 7 days, 14 days investigation prevention effects after the second application.Examination
Test that the results are shown in Table 2：
Field test results are as shown in table 2, and folpet and the independent dispenser of fluorine azoles bacterium aniline have rice sheath blight disease certain anti-
Control effect, and the raising for rationally increasing advantageous preventive effect of dosage, but pharmaceutical use needs significantly improve, preventive effect with when
Between extension, gradually weaken.Contrastingly, to rice sheath blight disease after second of dispenser of mixture of folpet and fluorine azoles bacterium aniline
Control effect is substantially better than the control effect of two kinds of single doses.And the preventive effect after dispenser 14 days is generally better than the prevention after 7 days
Effect shows apparent synergistic effect to the control effect of crops.It is fool proof to trial crops during experiment, without poisoning
Reaction.
Claims (9)
1. a kind of bactericide pesticide composite, which is characterized in that its active constituent includes folpet and fluorine azoles bacterium aniline.
2. microbicide compositions according to claim 1, which is characterized in that the weight of the folpet and fluorine azoles bacterium aniline
Proportioning is 1:50~50:1.
3. microbicide compositions according to claim 2, which is characterized in that the weight of the folpet and fluorine azoles bacterium aniline
Than being 1:20~20:1.
4. microbicide compositions according to claim 3, which is characterized in that the weight of the folpet and fluorine azoles bacterium aniline
It is preferred that than being 5:1.
5. according to the microbicide compositions described in any one of claim 1-4, which is characterized in that active constituent accounts for composition
Weight percentage be 1-90%, preferably 20-80%.
6. according to the microbicide compositions described in any one of claim 1-5, which is characterized in that the microbicide compositions
Further include agricultural agent, the auxiliary agent includes emulsifier, wetting agent, dispersant, antifreezing agent, solvent, cosolvent, thickener, disappears
It is one or more in infusion, disintegrant etc.；Content of the auxiliary agent in microbicide compositions is 1-99%.
7. according to the microbicide compositions described in claim 1-6 any one, which is characterized in that the dosage form of composition is wettable
Property pulvis, water dispersible granules, missible oil, suspending agent, microcapsule suspending agent, microemulsion, aqueous emulsion, suspension seed-coating agent etc.；It is further excellent
Turn to wettable powder, missible oil, suspending agent, water dispersible granules.
8. the microbicide compositions described in claim 7 are used to prevent the purposes of fungus-caused plant disease.
9. purposes according to claim 8, wherein the plant disease includes but not limited to sclerotinia sclerotiorum, wheat white powder
Disease, rust, banded sclerotial blight, damping-off, smut, black scurf of potato, corn southern leaf blight, downy mildew of garpe, white rot, anthrax
Disease, ring rot of apple, spot defoliation, anthracnose, brown spot, leaf muld of tomato.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710310374.7A CN108782578A (en) | 2017-05-05 | 2017-05-05 | Composition pesticide containing folpet and fluorine azoles bacterium aniline |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710310374.7A CN108782578A (en) | 2017-05-05 | 2017-05-05 | Composition pesticide containing folpet and fluorine azoles bacterium aniline |
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| Publication Number | Publication Date |
|---|---|
| CN108782578A true CN108782578A (en) | 2018-11-13 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710310374.7A Pending CN108782578A (en) | 2017-05-05 | 2017-05-05 | Composition pesticide containing folpet and fluorine azoles bacterium aniline |
Country Status (1)
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| CN (1) | CN108782578A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2020141512A1 (en) * | 2018-12-31 | 2020-07-09 | Adama Makhteshim Ltd. | Fungicidal mixture |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1229580A (en) * | 1998-01-27 | 1999-09-29 | 罗姆和哈斯公司 | Fungicidal compositions containing N-acetonylbenzamides |
-
2017
- 2017-05-05 CN CN201710310374.7A patent/CN108782578A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1229580A (en) * | 1998-01-27 | 1999-09-29 | 罗姆和哈斯公司 | Fungicidal compositions containing N-acetonylbenzamides |
Non-Patent Citations (1)
| Title |
|---|
| 山边正显: "《无处不在的氟》", 31 October 2014, 中国科学技术大学出版社 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2020141512A1 (en) * | 2018-12-31 | 2020-07-09 | Adama Makhteshim Ltd. | Fungicidal mixture |
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Application publication date: 20181113 |