CN107494550A - A kind of bactericidal composition containing fluorine azoles bacterium acyl azanol and 2-cyano-3-amino-3-phenylancryic acetate - Google Patents
A kind of bactericidal composition containing fluorine azoles bacterium acyl azanol and 2-cyano-3-amino-3-phenylancryic acetate Download PDFInfo
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- CN107494550A CN107494550A CN201710808059.7A CN201710808059A CN107494550A CN 107494550 A CN107494550 A CN 107494550A CN 201710808059 A CN201710808059 A CN 201710808059A CN 107494550 A CN107494550 A CN 107494550A
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- cyano
- amino
- fluorine azoles
- azoles bacterium
- phenylancryic acetate
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- 241000894006 Bacteria Species 0.000 title claims abstract description 70
- -1 acyl azanol Chemical compound 0.000 title claims abstract description 67
- 239000000203 mixture Substances 0.000 title claims abstract description 65
- WHDHEVMINMZADQ-UHFFFAOYSA-N [F].N1C=CC=C1 Chemical class [F].N1C=CC=C1 WHDHEVMINMZADQ-UHFFFAOYSA-N 0.000 title claims abstract description 63
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 title claims abstract description 60
- 230000000844 anti-bacterial effect Effects 0.000 title claims abstract description 25
- 241000209140 Triticum Species 0.000 claims abstract description 20
- 235000021307 Triticum Nutrition 0.000 claims abstract description 20
- 206010039509 Scab Diseases 0.000 claims abstract description 15
- 239000000375 suspending agent Substances 0.000 claims abstract description 8
- 239000004562 water dispersible granule Substances 0.000 claims abstract description 8
- 239000004480 active ingredient Substances 0.000 claims abstract description 6
- 238000009472 formulation Methods 0.000 claims abstract description 5
- 230000003405 preventing effect Effects 0.000 claims abstract description 5
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 6
- 210000000481 breast Anatomy 0.000 claims description 4
- RCEAADKTGXTDOA-UHFFFAOYSA-N OS(O)(=O)=O.CCCCCCCCCCCC[Na] Chemical compound OS(O)(=O)=O.CCCCCCCCCCCC[Na] RCEAADKTGXTDOA-UHFFFAOYSA-N 0.000 claims description 2
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 claims description 2
- 239000008367 deionised water Substances 0.000 claims description 2
- 229910021641 deionized water Inorganic materials 0.000 claims description 2
- 239000007884 disintegrant Substances 0.000 claims description 2
- YDEXUEFDPVHGHE-GGMCWBHBSA-L disodium;(2r)-3-(2-hydroxy-3-methoxyphenyl)-2-[2-methoxy-4-(3-sulfonatopropyl)phenoxy]propane-1-sulfonate Chemical compound [Na+].[Na+].COC1=CC=CC(C[C@H](CS([O-])(=O)=O)OC=2C(=CC(CCCS([O-])(=O)=O)=CC=2)OC)=C1O YDEXUEFDPVHGHE-GGMCWBHBSA-L 0.000 claims description 2
- PSZYNBSKGUBXEH-UHFFFAOYSA-M naphthalene-1-sulfonate Chemical compound C1=CC=C2C(S(=O)(=O)[O-])=CC=CC2=C1 PSZYNBSKGUBXEH-UHFFFAOYSA-M 0.000 claims description 2
- 229910052710 silicon Inorganic materials 0.000 claims description 2
- 239000010703 silicon Substances 0.000 claims description 2
- 239000002689 soil Substances 0.000 claims description 2
- 229920001285 xanthan gum Polymers 0.000 claims description 2
- AVXURJPOCDRRFD-UHFFFAOYSA-N Hydroxylamine Chemical group ON AVXURJPOCDRRFD-UHFFFAOYSA-N 0.000 claims 1
- 229920001732 Lignosulfonate Polymers 0.000 claims 1
- 125000002252 acyl group Chemical group 0.000 claims 1
- 239000002518 antifoaming agent Substances 0.000 claims 1
- 230000008961 swelling Effects 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract description 16
- 201000010099 disease Diseases 0.000 abstract description 15
- 238000012360 testing method Methods 0.000 abstract description 12
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- 230000002265 prevention Effects 0.000 abstract description 6
- 238000005507 spraying Methods 0.000 abstract description 6
- 241000223218 Fusarium Species 0.000 abstract description 3
- 230000007613 environmental effect Effects 0.000 abstract 1
- 239000003814 drug Substances 0.000 description 20
- 150000001875 compounds Chemical class 0.000 description 9
- 238000000034 method Methods 0.000 description 8
- 230000003449 preventive effect Effects 0.000 description 8
- 239000003795 chemical substances by application Substances 0.000 description 7
- 230000003902 lesion Effects 0.000 description 5
- JMANVNJQNLATNU-UHFFFAOYSA-N oxalonitrile Chemical compound N#CC#N JMANVNJQNLATNU-UHFFFAOYSA-N 0.000 description 5
- 239000003153 chemical reaction reagent Substances 0.000 description 4
- 150000002148 esters Chemical class 0.000 description 4
- 238000002474 experimental method Methods 0.000 description 4
- 239000000843 powder Substances 0.000 description 4
- 238000012545 processing Methods 0.000 description 4
- 239000007921 spray Substances 0.000 description 4
- 230000002195 synergetic effect Effects 0.000 description 4
- 241000233866 Fungi Species 0.000 description 3
- 230000002411 adverse Effects 0.000 description 3
- 239000003905 agrochemical Substances 0.000 description 3
- 230000015572 biosynthetic process Effects 0.000 description 3
- 229940079593 drug Drugs 0.000 description 3
- 230000001954 sterilising effect Effects 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 230000001225 therapeutic effect Effects 0.000 description 3
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 2
- 241000085543 Acourtia wrightii Species 0.000 description 2
- 240000007582 Corylus avellana Species 0.000 description 2
- 235000007466 Corylus avellana Nutrition 0.000 description 2
- 206010059866 Drug resistance Diseases 0.000 description 2
- 241000223195 Fusarium graminearum Species 0.000 description 2
- 150000003851 azoles Chemical class 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 239000013530 defoamer Substances 0.000 description 2
- 230000000857 drug effect Effects 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 208000010801 foot rot Diseases 0.000 description 2
- 230000002401 inhibitory effect Effects 0.000 description 2
- 230000005764 inhibitory process Effects 0.000 description 2
- JEIPFZHSYJVQDO-UHFFFAOYSA-N iron(III) oxide Inorganic materials O=[Fe]O[Fe]=O JEIPFZHSYJVQDO-UHFFFAOYSA-N 0.000 description 2
- 231100000572 poisoning Toxicity 0.000 description 2
- 230000000607 poisoning effect Effects 0.000 description 2
- 239000002994 raw material Substances 0.000 description 2
- 230000002829 reductive effect Effects 0.000 description 2
- 230000004763 spore germination Effects 0.000 description 2
- 238000004659 sterilization and disinfection Methods 0.000 description 2
- 238000003786 synthesis reaction Methods 0.000 description 2
- 231100000820 toxicity test Toxicity 0.000 description 2
- 230000001018 virulence Effects 0.000 description 2
- UHPMCKVQTMMPCG-UHFFFAOYSA-N 5,8-dihydroxy-2-methoxy-6-methyl-7-(2-oxopropyl)naphthalene-1,4-dione Chemical compound CC1=C(CC(C)=O)C(O)=C2C(=O)C(OC)=CC(=O)C2=C1O UHPMCKVQTMMPCG-UHFFFAOYSA-N 0.000 description 1
- 241000235349 Ascomycota Species 0.000 description 1
- 241000221198 Basidiomycota Species 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- YCKRFDGAMUMZLT-UHFFFAOYSA-N Fluorine atom Chemical compound [F] YCKRFDGAMUMZLT-UHFFFAOYSA-N 0.000 description 1
- 240000007594 Oryza sativa Species 0.000 description 1
- 235000007164 Oryza sativa Nutrition 0.000 description 1
- 244000046052 Phaseolus vulgaris Species 0.000 description 1
- 235000010627 Phaseolus vulgaris Nutrition 0.000 description 1
- 244000061456 Solanum tuberosum Species 0.000 description 1
- 235000002595 Solanum tuberosum Nutrition 0.000 description 1
- 102000019259 Succinate Dehydrogenase Human genes 0.000 description 1
- 108010012901 Succinate Dehydrogenase Proteins 0.000 description 1
- 240000000359 Triticum dicoccon Species 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 238000012271 agricultural production Methods 0.000 description 1
- 150000001336 alkenes Chemical class 0.000 description 1
- 230000008485 antagonism Effects 0.000 description 1
- 239000012752 auxiliary agent Substances 0.000 description 1
- 239000003899 bactericide agent Substances 0.000 description 1
- 241000933856 bacterium 8 Species 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000000440 bentonite Substances 0.000 description 1
- 229910000278 bentonite Inorganic materials 0.000 description 1
- SVPXDRXYRYOSEX-UHFFFAOYSA-N bentoquatam Chemical compound O.O=[Si]=O.O=[Al]O[Al]=O SVPXDRXYRYOSEX-UHFFFAOYSA-N 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
- 238000004364 calculation method Methods 0.000 description 1
- 235000013339 cereals Nutrition 0.000 description 1
- 235000016213 coffee Nutrition 0.000 description 1
- 235000013353 coffee beverage Nutrition 0.000 description 1
- 230000000295 complement effect Effects 0.000 description 1
- 230000009514 concussion Effects 0.000 description 1
- 230000001934 delay Effects 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 239000000645 desinfectant Substances 0.000 description 1
- 230000002554 disease preventive effect Effects 0.000 description 1
- 239000002270 dispersing agent Substances 0.000 description 1
- 239000000890 drug combination Substances 0.000 description 1
- 210000005069 ears Anatomy 0.000 description 1
- 238000004945 emulsification Methods 0.000 description 1
- 239000003995 emulsifying agent Substances 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 238000013401 experimental design Methods 0.000 description 1
- 239000000945 filler Substances 0.000 description 1
- 229910052731 fluorine Inorganic materials 0.000 description 1
- 239000011737 fluorine Substances 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 239000003112 inhibitor Substances 0.000 description 1
- 230000001788 irregular Effects 0.000 description 1
- 230000002147 killing effect Effects 0.000 description 1
- 230000002045 lasting effect Effects 0.000 description 1
- 229920005610 lignin Polymers 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 230000035800 maturation Effects 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 230000010534 mechanism of action Effects 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 239000012452 mother liquor Substances 0.000 description 1
- 230000035772 mutation Effects 0.000 description 1
- 239000003002 pH adjusting agent Substances 0.000 description 1
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- 230000009885 systemic effect Effects 0.000 description 1
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- 235000013311 vegetables Nutrition 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/44—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/56—1,2-Diazoles; Hydrogenated 1,2-diazoles
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- Life Sciences & Earth Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The present invention relates to a kind of bactericidal composition containing fluorine azoles bacterium acyl azanol and 2-cyano-3-amino-3-phenylancryic acetate, the ratio of weight and number in the composition of active ingredient fluorine azoles bacterium acyl azanol and 2-cyano-3-amino-3-phenylancryic acetate is 1:20‑20:1；Water dispersible granules can be made in bactericidal composition of the present invention, suspending agent spraying uses, and be mainly used in preventing and treating wheat scab, show that the complex preparation has good prevention effect to gibberella saubinetii disease bacterium by field test measure.Formulation of the present invention environmental protection, selectivity is strong, using simple, has extremely strong operability and actual application value.
Description
Technical field
The present invention relates to a kind of disinfectant use in agriculture, and in particular to a kind of sterilization containing fluorine azoles bacterium acyl azanol and 2-cyano-3-amino-3-phenylancryic acetate
Composition, for preventing and treating wheat scab.
Background technology
Fluorine azoles bacterium acyl azanol belongs to succinate dehydrogenase inhibitors, and fluorine azoles bacterium acyl azanol application optimum period is wide, no matter in fungi
Early stage such as spore germination, germ tube growth and intrusion leaf portion are infected, or extraordinary protection can be provided in growth period of hypha
And therapeutic action；But spore germination and initial stage are infected most effective.Because of the excellent systemic activity having, it can quickly be inhaled
Receive, and can equably be transmitted in leaf portion to top, therefore there is good resistance of rainwater washing against ability.Suitable for crop and security cereal
Class crop, potato, vegetables and coffee etc., to crop safety under recommended dose.The sterilization that fluorine azoles bacterium acyl azanol has wide spectrum is lived
Property, to nearly all Mycophytes (Ascomycetes, Basidiomycetes and Fungi Imperfecti) disease such as rust, clever blessing disease, net blotch, red mould
The tens of kinds of diseases such as disease have good activity.
2-cyano-3-amino-3-phenylancryic acetate belongs to methoxy acrylic bactericide, in addition to having special efficacy to crops head blight, to beans
Rust, the disease such as sigatoka also there is good prevention effect.There is pole to mycelium, conidium, receptive hypha etc.
Strong killing effect, and can strongly suppress the formation of spore, block spore to infect source again, bactericidal effect is comprehensively thorough.For
The crop to have fallen ill, 2-cyano-3-amino-3-phenylancryic acetate can play therapeutic action well, can root out the germ in invaded plantses body, energy
Enough obvious extensions for suppressing germ.
There is generation wheat scab all parts of the country, and this disease most easily occurs for northern rice wheat rotation area.Because head blight is mainly endangered
Evil fringe portion, very big loss is caused to Wheat During Later Period of Growth yield.
Wheat scab mainly causes that seedling is withered, fringe is rotten, brown foot rot, stalk are rotten and fringe is rotten, all can be aggrieved to heading from seedling.Its
Middle influence most serious is fringe corruption.Seedling corruption is caused by invalid body infects in seed-borne fungi or soil.Bud mutation was brown before this, then root cap
Rot therewith, the lighter's sick seedling Huang is thin, and severe one is dead, produces pink mustiness thing during withered seedling high humidity.The fringe portion later stage produces thereon
Raw intensive black-and-blue little particle (the germ shell of ascus).Seed is shrivelled and mould to pink with white.Extended after small ear morbidity
To cob, sick portion is withered brown, makes killed portion's above small ear, forms withered dead ears.Brown foot rot can occur from coming up to maturation, wheat
Browning rots after strain base portion tissue is aggrieved, causes complete stool withered.Stalk corruption mostly occurs under fringe first and second section, just occurs on leaf sheath
Water stain shape chlorisis spot, after expand to and filbert extended to bronzing irregular shape spot or into stem.When being in a bad way, disease portion is caused
More than it is withered and yellow, can not ear sometimes or extract withered and yellow fringe out.The visible pink mould layer in disease portion surface when having a humid climate
In factual survey research, it has been found that compounded fluorine azoles bacterium acyl azanol, 2-cyano-3-amino-3-phenylancryic acetate, to gibberella saubinetii
Disease has obviously preventive and therapeutic effect, the complex agent type, is difficult to produce in actual application according to long-term tracking test
Resistance.And in use, dosage is very low, the negative effect very little to environment.
The content of the invention
It is an object of the invention to provide a kind of bactericidal composition containing azoles bacterium acyl azanol and 2-cyano-3-amino-3-phenylancryic acetate, for preventing and treating
Wheat scab.
The technical scheme is that：A kind of bactericidal composition containing fluorine azoles bacterium acyl azanol and 2-cyano-3-amino-3-phenylancryic acetate, effectively into
It is 1 to divide the ratio of weight and number in the composition of fluorine azoles bacterium acyl azanol and 2-cyano-3-amino-3-phenylancryic acetate:20-20:1, fluorine azoles bacterium acyl azanol and cyanogen
Percentage by weight is 1%~60% to alkene bacterium ester weight summation in the composition.
Further, the preferred weight portion rate in the composition of active ingredient fluorine azoles bacterium acyl azanol and 2-cyano-3-amino-3-phenylancryic acetate is 1:
1。
Bactericidal composition of the present invention can be prepared into any application forms used in suitable agricultural production, and relatively good should
There are suspending agent, water dispersible granules with formulation.
In various application forms prepared by bactericidal composition of the present invention, in addition to active ingredient, in addition to allow in agricultural chemicals
Using with the various auxiliary elements of acceptable.
Auxiliary element described in bactericidal composition of the present invention is solvent, emulsifying agent, wetting agent, stabilizer, dispersant, thickening
One or more of mixing in agent, pH adjusting agent, defoamer, antifreezing agent, filler etc., are known substance, are pesticidal preparations
In commonly use various auxiliary agents, can be varied from, be not particularly limited according to different situations.
The bactericidal composition of the present invention can be used for preventing and treating wheat scab.
The bactericidal composition generally use spray method of the present invention uses, and can also use what is agriculturally applied as needed
Other use technology.
Compared with prior art, had the beneficial effect that caused by the present invention：
1st, bactericidal composition provided by the invention, obvious synergistic effect, composition are shown in certain ratio range
The prevention effect of germ is significantly improved than single dose, the dosage of agricultural chemicals is reduced, reduces times for spraying, reduce
Drug cost, reduce adverse effect of the agricultural chemicals to ecological environment.
2nd, bactericidal composition provided by the invention, two kinds of active ingredient mechanism of action are different, can overcome single for a long time make
The shortcomings that with easy generation resistance, extend the service life of medicament, the comprehensive regulation important in inhibiting to germ resistance.
3rd, bactericidal composition provided by the invention, drug effect play rapidly, and the lasting period is longer, and use cost is low, easy to use,
Time saving and energy saving, its popularization and application has huge economic benefit and social benefit.
Embodiment
Experimental design and drug solution preparing：
| Processing numbering | Medicament | Quality (g) |
| ① | The 2-cyano-3-amino-3-phenylancryic acetate of 5% fluorine azoles bacterium acyl azanol+50% | 0.010+0.095 |
| ② | The 2-cyano-3-amino-3-phenylancryic acetate of 10% fluorine azoles bacterium acyl azanol+40% | 0.021+0.083 |
| ③ | The 2-cyano-3-amino-3-phenylancryic acetate of 20% fluorine azoles bacterium acyl azanol+30% | 0.042+0.063 |
| ④ | The 2-cyano-3-amino-3-phenylancryic acetate of 30% fluorine azoles bacterium acyl azanol+20% | 0.063+0.042 |
| ⑤ | The 2-cyano-3-amino-3-phenylancryic acetate of 40% fluorine azoles bacterium acyl azanol+10% | 0.084+0.021 |
| ⑥ | The 2-cyano-3-amino-3-phenylancryic acetate of 50% fluorine azoles bacterium acyl azanol+5% | 0.096+0.009 |
| ⑦ | 95% fluorine azoles bacterium acyl azanol active compound | 0.1053 |
| ⑧ | 96% 2-cyano-3-amino-3-phenylancryic acetate active compound | 0.1042 |
Will be for 95% fluorine azoles bacterium acyl azanol active compound of examination and 96% 2-cyano-3-amino-3-phenylancryic acetate active compound and 6 fluorine azoles bacterium acyl azanol+cyanogen alkene bacterium
8 medicaments such as ester mixture, weigh medicament according to the requirement of upper form and add in advance plus in the sterilizing triangular flask of good 2mL acetone, fill
Concussion is divided to make its dissolving, then plus sterilized water is to 1000mL, and it is standby that each 1000mL of 100 μ g/mL experiment mother liquors is made.Tried in preparation
On the basis of testing, the mother liquor configured is diluted to 5 concentration gradients from high to low by concentration respectively, respectively is 100 μ g/
mL、50μg/mL、25μg/mL、12.5μg/mL、6.25μg/mL。
Chemicals treatment：
| Processing numbering | Chemicals treatment | Active compound amount (g) | Active ingredient (g) |
| ① | The 2-cyano-3-amino-3-phenylancryic acetate of 5% fluorine azoles bacterium acyl azanol+50% | 0.010+0.095 | 0.010+0.091 |
| ② | The 2-cyano-3-amino-3-phenylancryic acetate of 10% fluorine azoles bacterium acyl azanol+40% | 0.021+0.083 | 0.020+0.080 |
| ③ | The 2-cyano-3-amino-3-phenylancryic acetate of 20% fluorine azoles bacterium acyl azanol+30% | 0.042+0.063 | 0.040+0.060 |
| ④ | The 2-cyano-3-amino-3-phenylancryic acetate of 30% fluorine azoles bacterium acyl azanol+20% | 0.063+0.042 | 0.060+0.040 |
| ⑤ | The 2-cyano-3-amino-3-phenylancryic acetate of 40% fluorine azoles bacterium acyl azanol+10% | 0.084+0.021 | 0.080+0.020 |
| ⑥ | The 2-cyano-3-amino-3-phenylancryic acetate of 50% fluorine azoles bacterium acyl azanol+5% | 0.096+0.009 | 0.091+0.009 |
| ⑦ | 95% fluorine azoles bacterium acyl azanol active compound | 0.1053 | 0.100 |
| ⑧ | 96% 2-cyano-3-amino-3-phenylancryic acetate active compound | 0.1042 | 0.100 |
| ⑨ | Clear water compares | - | - |
Wheat cauline leaf spray-on process dispenser (having water membrane to be advisable with blade surface) is used, spray apparatus is using manual
Sprayer (liquid capacity about 2.0L), it is every 10 days sprays once, continuous to spray 2 times.Often processing selects one to fall ill uniform 1 year
Raw 20 blades of branch each handle 3 repetitions as efficacy of medicine observing object.
Method of evaluating drug effect：
0 grade：Disease-free spot；
1 grade：Lesion area accounts for less than the 5% of whole leaf area；
3 grades：Lesion area accounts for the 6%-15% of whole leaf area；
5 grades：Lesion area accounts for the 16%-25% of whole leaf area；
7 grades：Lesion area accounts for the 26%-50% of whole leaf area；
9 grades：Lesion area accounts for more than the 50% of whole leaf area.
Data computation processing method：
According to survey data, the disease index and prevention effect of each processing are calculated.
Disease index is calculated by formula, and result of calculation retains 2 significant digits：
When carrying out drug combination toxicity test, this experiment calculates the coefficient of synergism (SR) of mixture, evaluation using Wadley methods
The synergy type of mixture.
Wadley methods：The synergistic effect of pharmacy mix, i.e. SR are evaluated according to coefficient of synergism (SR)<0.5 is antagonism,
0.5≤SR≤1.5 are summation action, SR>1.5 be synergistic function.Coefficient of synergism (SR) is calculated by formula (1), (2)：
In formula：
X1------ mixtures EC50Theoretical value, unit are milligrams per liter (mg/L)；
PAA percentage composition in --- ----mixture, unit are percentage (%)；
PB--- -- in mixture B percentage composition, unit is percentage (%)；
A EC in A----- mixtures50Value, unit is milligrams per liter (mg/L)；
B EC in B----- mixtures50Value, unit is milligrams per liter (mg/L).
In formula：
The coefficient of synergism of SR------ mixtures；
The EC of X1------ mixtures50Theoretical value, unit are milligrams per liter (mg/L)；
The EC of X2------ mixtures50Measured value, unit are milligrams per liter (mg/L).
Interpretation of result is with discussing：
Fluorine azoles bacterium acyl azanol and 2-cyano-3-amino-3-phenylancryic acetate the results are shown in Table 1 to the toxicity test of fusarium graminearum.From table 1, fluorine
EC of the azoles bacterium acyl azanol with 2-cyano-3-amino-3-phenylancryic acetate to fusarium graminearum50Value is respectively 13.40 and 19.22 μ g/mL, and 2-cyano-3-amino-3-phenylancryic acetate is to small
The virulence of wheat head blight is higher than medicament fluorine azoles bacterium acyl azanol.
Fluorine azoles bacterium acyl azanol active compound and 2-cyano-3-amino-3-phenylancryic acetate active compound and its two 6 kinds of different blended are measured with combining to wheat scab
The inhibition of bacterium, then with the logarithm value (X) of drug concentration for independent variable, with the niqueMin (Y) of inhibiting rate for dependent variable, adopt
The virulence regression equation and EC of a medicament are obtained with least square method50And R values.Obtained according to Wadley (1945,1967) each
Mixture combination synergism value SR (seeing attached list 1).
As a result show and (see attached list 1), fluorine azoles bacterium acyl azanol and 2-cyano-3-amino-3-phenylancryic acetate are according to 1：10-10:1 ratio mixture, to small
The inhibition of wheat gibberellic hypha shows synergistic effect.
Table 1, fluorine azoles bacterium acyl azanol are matched somebody with somebody with 2-cyano-3-amino-3-phenylancryic acetate different blended to be combined to fusarium graminearum measurement result.
Example of formulations one：24% fluorine azoles bacterium acyl azanol 2-cyano-3-amino-3-phenylancryic acetate (1:1) suspending agent.
Weigh 12% fluorine azoles bacterium acyl azanol, 12% 2-cyano-3-amino-3-phenylancryic acetate, 2% agriculture breast 602,4% agriculture breast 2201,3% sulfomethylated lignin
Hydrochlorate, 0.2% xanthans, 4% ethylene glycol, 0.5% organic silicon defoamer, add deionized water to mend to 100%.Above-mentioned raw materials are mixed
After conjunction, 24% fluorine azoles bacterium acyl azanol 2-cyano-3-amino-3-phenylancryic acetate suspending agent is made by high speed shearing emulsification.
Example of formulations two：48% fluorine azoles bacterium acyl azanol 2-cyano-3-amino-3-phenylancryic acetate water dispersible granules.
Weigh 24% fluorine azoles bacterium acyl azanol, 24% 2-cyano-3-amino-3-phenylancryic acetate, 4% lauryl sodium sulfate, 12% sodium lignin sulfonate,
6% naphthalene sulfonate, 1.2% disintegrant, bentonite complement to 100%.After above-mentioned raw materials are mixed, it is milled by airslide disintegrating mill
It is granulated, 48% fluorine azoles bacterium acyl azanol 2-cyano-3-amino-3-phenylancryic acetate water dispersible granules is made.
Field control effectiveness test embodiment one：
Reagent agent and dispenser dosage：
(1) 24% fluorine azoles bacterium acyl azanol 2-cyano-3-amino-3-phenylancryic acetate suspending agent (1:1), 50 grams of preparation of mu
(2) 48% fluorine azoles bacterium acyl azanol 2-cyano-3-amino-3-phenylancryic acetate water dispersible granules (1:1), 60 grams of comparison medicaments of mu preparation and apply
Pharmaceutical quantities：
(3) 20% fluorine azoles bacterium acyl azanol wettable powders, 60 grams of preparation of mu
(4) 20% 2-cyano-3-amino-3-phenylancryic acetate wettable powders, mu 60 grams of spraying times of preparation and application method：Wheat scab is sent out
Sick dispenser at initial stage, is watered even spraying.
Table 2 prevents and treats the field control effectiveness test result of wheat scab
| Reagent agent | Preparation usage amount (gram/acre) | 7 days preventive effects (%) after medicine | 14 days preventive effects (%) after medicine |
| 1 | 50 | 74.6 | 86.7 |
| 2 | 30 | 78.1 | 88.9 |
| 3 | 60 | 65.3 | 72.3 |
| 4 | 60 | 61.6 | 77.8 |
Result of the test：2 are shown in Table, as can be seen from the test results：7 days after dispenser, fluorine azoles bacterium acyl azanol of the invention and cyanogen
Alkene bacterium ester mixture composition is to wheat scab preventive effect all more than 70%, hence it is evident that is better than the single dose of control；14 days after dispenser, this
The fluorine azoles bacterium acyl azanol and 2-cyano-3-amino-3-phenylancryic acetate mixture composition of invention all more than 80%, are also significantly better than to wheat scab preventive effect
The single dose of control；Each medicament is showed no poisoning generation during experiment, to crop safety.Illustrate the fluorine azoles bacterium acyl azanol of the present invention
It is better than single dose with 2-cyano-3-amino-3-phenylancryic acetate mixture composition, improves actual prevention effect, reduce dosage, reduce cost, reduces medicament pair
The adverse effect of environment, delay the generation of disease drug resistance, agricultural synthesis, which is administered, to have great significance.
Field control effectiveness test embodiment two：
Reagent agent and dispenser dosage：
(1) 24% fluorine azoles bacterium acyl azanol 2-cyano-3-amino-3-phenylancryic acetate suspending agent (1:1), 350 times of extension rate.
(2) 48% fluorine azoles bacterium acyl azanol 2-cyano-3-amino-3-phenylancryic acetate water dispersible granules (1:1), 700 times of extension rate.
Comparison medicament and dispenser dosage：
(3) 20% fluorine azoles bacterium acyl azanol wettable powders, 1000 times of preparation of mu.
(4) 20% 2-cyano-3-amino-3-phenylancryic acetate wettable powders, 1000 times of preparation of mu.
Spraying time and application method：Rice field early stage dispenser, is watered even spraying.
Table 3 prevents and treats the field control effectiveness test result of wheat scab disease
| Reagent agent | Preparation usage amount (multiple) | 7 days preventive effects (%) after medicine | 14 days preventive effects (%) after medicine |
| 1 | 350 | 78.9 | 87.5 |
| 2 | 700 | 77.5 | 89.9 |
| 3 | 250 | 64.7 | 74.1 |
| 4 | 250 | 70.6 | 76.6 |
Result of the test：3 are shown in Table, as can be seen from the test results：7 days after dispenser, fluorine azoles bacterium acyl azanol of the invention and cyanogen
Alkene bacterium ester mixture composition is to wheat scab disease preventive effect all more than 77%, hence it is evident that is better than the single dose of control；After secondary dispenser
14 days, fluorine azoles bacterium acyl azanol of the invention and 2-cyano-3-amino-3-phenylancryic acetate mixture composition to wheat scab preventive effect all more than 80%,
Significantly better than the single dose of control.
By above-mentioned field test, each medicament is showed no poisoning generation during finding experiment, to crop safety.The present invention
Fluorine azoles bacterium acyl azanol and 2-cyano-3-amino-3-phenylancryic acetate mixture composition be better than single dose, it is possible to increase actual prevention effect, reduce dosage, drop
Low cost, medicament is reduced to the adverse effect of environment, delays the generation of disease drug resistance, has to agricultural synthesis improvement important
Meaning.
Claims (6)
- A kind of 1. bactericidal composition containing fluorine azoles bacterium acyl azanol and 2-cyano-3-amino-3-phenylancryic acetate, it is characterised in that：Active ingredient fluorine azoles bacterium acyl The ratio of weight and number in the composition of azanol and 2-cyano-3-amino-3-phenylancryic acetate is 1:20-20:1, fluorine azoles bacterium acyl azanol and 2-cyano-3-amino-3-phenylancryic acetate weight Percentage by weight is 1%~60% to summation in the composition.
- 2. a kind of bactericidal composition containing fluorine azoles bacterium acyl azanol and 2-cyano-3-amino-3-phenylancryic acetate according to claim 1, its feature exist In：The ratio of weight and number in the composition of fluorine azoles bacterium acyl azanol and 2-cyano-3-amino-3-phenylancryic acetate is 1:10-10:1.
- 3. a kind of bactericidal composition containing fluorine azoles bacterium acyl azanol and 2-cyano-3-amino-3-phenylancryic acetate according to claim 1, its feature exist In：The formulation of the bactericidal composition is one kind in suspending agent, water dispersible granules.
- 4. a kind of bactericidal composition containing fluorine azoles bacterium acyl azanol and 2-cyano-3-amino-3-phenylancryic acetate according to claim 1 is for preventing and treating The application of wheat scab.
- 5. a kind of bactericidal composition containing fluorine azoles bacterium acyl azanol and 2-cyano-3-amino-3-phenylancryic acetate according to claim 3, its feature exist In when suspending agent is made in the bactericidal composition, each component weight percentage is：Weigh 12% fluorine azoles bacterium acyl azanol, 12% 2-cyano-3-amino-3-phenylancryic acetate, 2% agriculture breast 602,4% agriculture breast 2201,3% lignosulfonates, 0.2% xanthans, 4% ethylene glycol, 0.5% have Machine silicon defoaming agent, deionized water is added to mend to 100%.
- 6. a kind of bactericidal composition containing fluorine azoles bacterium acyl azanol and 2-cyano-3-amino-3-phenylancryic acetate according to claim 3, its feature exist In when water dispersible granules are made in the bactericidal composition, each component weight percentage is：Weigh 24% fluorine azoles bacterium acyl azanol, 24% 2-cyano-3-amino-3-phenylancryic acetate, 4% lauryl sodium sulfate, 12% sodium lignin sulfonate, 6% naphthalene sulfonate, 1.2% disintegrant, swelling Soil complements to 100%.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108294008A (en) * | 2018-02-02 | 2018-07-20 | 深圳诺普信农化股份有限公司 | Bactericidal composition |
| CN109362727A (en) * | 2018-12-13 | 2019-02-22 | 安阳工学院 | A kind of wheat scab biocontrol preparation and preparation method thereof |
| CN109566627A (en) * | 2017-09-29 | 2019-04-05 | 江苏龙灯化学有限公司 | A kind of bactericidal composition |
-
2017
- 2017-09-08 CN CN201710808059.7A patent/CN107494550A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109566627A (en) * | 2017-09-29 | 2019-04-05 | 江苏龙灯化学有限公司 | A kind of bactericidal composition |
| CN108294008A (en) * | 2018-02-02 | 2018-07-20 | 深圳诺普信农化股份有限公司 | Bactericidal composition |
| CN109362727A (en) * | 2018-12-13 | 2019-02-22 | 安阳工学院 | A kind of wheat scab biocontrol preparation and preparation method thereof |
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