CN107018984A - A kind of bactericidal composition containing folpet and fluoxastrobin and application thereof - Google Patents

A kind of bactericidal composition containing folpet and fluoxastrobin and application thereof Download PDF

Info

Publication number
CN107018984A
CN107018984A CN201710258727.3A CN201710258727A CN107018984A CN 107018984 A CN107018984 A CN 107018984A CN 201710258727 A CN201710258727 A CN 201710258727A CN 107018984 A CN107018984 A CN 107018984A
Authority
CN
China
Prior art keywords
fluoxastrobin
folpet
bactericidal composition
active ingredient
composition according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201710258727.3A
Other languages
Chinese (zh)
Inventor
殷素侠
彭军
刘世勇
吴光辉
王世银
陈锐东
陈志超
蔡丹群
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Guangdong Guangkang Biochemical Polytron Technologies Inc
Original Assignee
Guangdong Guangkang Biochemical Polytron Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Guangdong Guangkang Biochemical Polytron Technologies Inc filed Critical Guangdong Guangkang Biochemical Polytron Technologies Inc
Priority to CN201710258727.3A priority Critical patent/CN107018984A/en
Publication of CN107018984A publication Critical patent/CN107018984A/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/72Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
    • A01N43/88Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms six-membered rings with three ring hetero atoms
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/02Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having no bond to a nitrogen atom
    • A01N47/04Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having no bond to a nitrogen atom containing >N—S—C≡(Hal)3 groups

Abstract

The present invention relates to a kind of Synergistic bactericidal composition, comprising folpet and fluoxastrobin, the wherein mass ratio of active ingredient folpet and fluoxastrobin is 1~50: 50~1.Composition has obvious synergistic effect, available for preventing and treating agriculturally multiple diseases, preferably downy mildew, powdery mildew.

Description

A kind of bactericidal composition containing folpet and fluoxastrobin and application thereof
Technical field
The present invention relates to a kind of bactericidal composition and purposes, more particularly to a kind of sterilization containing folpet and fluoxastrobin Composition and application thereof, is mainly used in the preventing and treating of crop downy mildew and powdery mildew.
Background technology
Fluoxastrobin (Fluoxastrobin 193740-76-0), belongs to for Strobin series bactericidal agents, the mechanism of action Mitochondrial respiratory inhibitor, i.e., by between cytochrome b and Ct electro transfer suppress it is mitochondrial breathing be mainly used in stem Leaf processing.It has the bactericidal activity of wide spectrum, to nearly all Mycophytes (Ascomycetes, Basidiomycetes, Oomycete and Fungi Imperfecti Class) disease such as tens of kinds of diseases such as rust, glume blight, net blotch, powdery mildew, downy mildew have good activity.
Folpet(folpet 133-07-3), it is mainly used in a variety of diseases such as preventing and treating grain and oil crop, vegetables, fruit tree, flowers Evil, has stimulation to growth and development of plants, can prevent and treat rice blast, rice sheath blight disease, wheat rust, head blight, rape downy mildew Disease, leaf spot of peanut, the late blight of potato, tomato early blight, anthracnose of tobacco, apple anthracnose etc..
It facts have proved that resistance problem easily occurs in the long-term use of chemical pesticide single dose, cause consumption to continue to increase, risk Increase, is unfavorable for Environment Ecological Safe.Seek scientific and rational agriculture chemical compounding, be to solve the preferable method of this problem.Will not Pesticide active ingredient with structure type is compounded, and is current the problems such as solve cost and resistance in agricultural chemicals single dose application process A kind of effective means.After the pesticide active ingredient mixing of different types of structure, three kinds of type of action are typically exhibited, that is, are added Effect, synergistic effect and antagonism, but be specially which kind of effect, it is impossible to predict, only just can know that by lot of experiments.It is multiple It is formulated well with synergy, actual prevention effect can be improved, is reduced the usage amount of agricultural chemicals, contribute to the generation of delaying drug resistance, be The important means of scientific prevention and cure pest and disease damage.The relevant report at home and abroad also compounded at present without folpet and fluoxastrobin.
The content of the invention
It is an object of the invention to provide a kind of synergistic effect substantially, to downy mildew, controlling powdery mildew effect is good, cost is low, The low bactericidal composition of resistance risk.
It is a further object of the present invention to provide the application of the bactericidal composition.
Inventor is had been surprisingly found that certain with folpet and fluoxastrobin by substantial amounts of indoor biometricses and field control effectiveness test Ratio mixture after, have significant synergistic effect to diseases such as downy mildew, powdery mildews.
On the basis of above-mentioned discovery, by carrying out the quantitative analysis of synergy to composition, form the present invention's Technical scheme, i.e., using folpet and fluoxastrobin as active ingredient, the mass ratio of the two is 50:1-1:50, preferable quality ratio For 20:1-1:20.
In the bactericidal composition of the present invention, A and B mass accumulation percentage composition are 5%~90%, and remaining is auxiliary agent and filled out Material or diluent.
Said composition can be processed into any formulation agriculturally allowed, and preferable formulation has missible oil, suspending agent, wettable powder Agent, water dispersible granules, aqueous emulsion, microemulsion.
Advantageous effects
(1) learnt by substantial amounts of indoor and field control effectiveness test, the activity and bactericidal effect of bactericidal composition of the present invention It is not the simple superposition of each component activity, but shows significant synergistic effect.
(2) bactericidal composition of the present invention expands preventing and treating spectrum, and bactericidal effect is good, significantly improves a variety of farmings The multiple diseases of thing prevent effect, and the especially preventive effect to cucumber downy mildew, wheat powdery mildew is preferable.
(3) bactericidal composition of the present invention can be prepared as missible oil, suspending agent, wettable powder, water dispersible granules, The preparation of the different dosage forms such as aqueous emulsion, microemulsion, each preparation is good to crop safety, meets the security requirement of pesticidal preparations, It is suitable for popularizing application.
Embodiment
Biologicall test example one:Folpet and fluoxastrobin compound the toxicity test to cucumber downy mildew
Subjects:Bacterium of downy mildew of cucumber
Experiment is determined using pot-culture method.The consistent two panels leaf period cucumber seedling of growth is chosen, each processing is from 10 basins for examination melon Seedling, is numbered standby.Sprayed with Potter spray towers under 50PSI pressure, per basin 5mL.Each medicament sets 6 concentration gradients, To spray the processing of equivalent clear water as blank control.The downy mildew leaf for picking up from field is taken, 10 DEG C or so of distillation is dipped with writing brush The sporangium at the lower back side of washing, is made into the sporangia suspension that concentration is 3 × 105/mL.Connect in spraying after chemicals treatment 24h Spore cyst fluid is planted, cucumber seedling is placed in growth cabinet (relative humidity 100%, 15~20 DEG C of temperature) culture, 24h after inoculation 15~24 DEG C of keeping temperature, the moisturizing of relative humidity 90% or so are induced afterwards, and incidence is recorded in investigation after 10d, are calculated the state of an illness and are referred to Number and prevention effect.Concentration EC50 in suppressing is calculated with least square method, then co-toxicity coefficient (CTC) is calculated according to the abundant methods of Sun Yun.When CTC < 80, then composition show as antagonism, as 80 < CTC < 120, then composition shows as summation action, as CTC > 120, then composition show as synergistic effect.
Survey toxicity index (ATI)=(standard agent EC50/ reagent agent EC50) × 100
In theoretical toxicity index (TTI)=A medicament toxicity index × mixture in A percentage composition+B medicament toxicity index × mixture B percentage composition
Co-toxicity coefficient (CTC)=[mixture actual measurement toxicity index (ATI)/mixture theoretical toxicity index (TTI)] × 100
Toxicity test the results are shown in Table 1.
Result of the test shows that folpet and fluoxastrobin have synergistic effect to cucumber downy mildew, match 50:1-1:50 Between when, co-toxicity coefficient is all more than 120.0, optimum ratio 20:1-1:20.
Biologicall test example two:The toxicity test of folpet and fluoxastrobin to wheat powdery mildew
Subjects:Wheat powdery mildew (picks up from field Wild Wheats powdery mildew strain, and through isolating and purifying)
Test method:Experiment refers to People's Republic of China (PRC) agricultural industry criteria NY/T 1156.4-2006《Agricultural chemicals indoor biological The part of determination test criterion bactericide the 4th:Prevent and treat wheat powdery mildew experiment pot-culture method》, determined using pot-culture method.Indoor virulence is surveyed Determine result of the test and refer to table 2.
Result of the test shows that folpet and fluoxastrobin have synergistic effect to wheat powdery mildew, match 50:1-1:50 Between when, co-toxicity coefficient is all more than 120.0, optimum ratio 1:1.
Two kinds of reactive compounds can be processed into any one formulation of permission, preferably missible oil, suspending agent, wettable powder, water Dispersible granule, aqueous emulsion, microemulsion.The preparation that two kinds of active ingredients are processed into is illustrated with specific embodiment below, but should The preparation that two kinds of active components can be processed is not limited only to set forth below.
Embodiment 1:
By folpet 20g, fluoxastrobin 10g, lauryl sodium sulfate 3g, NNO4g, white carbon 5g, kaolin adds to 100g and mixed Compound carries out air-flow crushing, and it is 30% fluoxastrobin folpet wettable powder that active ingredient weight percentage, which is made,.
Embodiment 2:
By folpet 25g, fluoxastrobin 20g, lauryl sodium sulfate 5g, NNO7g, white carbon 10g, kaolin adds to 100g Mixture carries out air-flow crushing, and it is 45% fluoxastrobin folpet wettable powder that active ingredient weight percentage, which is made,.
Embodiment 3:
Weigh folpet 50g, fluoxastrobin 5g, phenethyl phenol polyethenoxy ether phosphate 3g, agriculture breast 33#2g, alkyl phenol polyoxy Vinethene 1g, 150# solvent naphtha 13g, adds water to 100g.The method that above raw material is routinely prepared into aqueous emulsion puts into mixing kettle High speed is mixed, and effective Ingredients Weight percentage composition is made for 55% fluoxastrobin folpet aqueous emulsion.
Embodiment 4:
Folpet 35g is weighed, fluoxastrobin 15g, calcium dodecyl benzene sulfonate 6g, phenethyl phenol polyethenoxy ether 10g, 150# is molten Agent is oily to 100g.Mixed in the method input mixing kettle that above raw material is routinely prepared to missible oil, effective Ingredients Weight hundred is made It is 50% fluoxastrobin folpet missible oil to divide content.
Embodiment 5:
Weigh folpet 10g, fluoxastrobin 10g, lignin 2g, polyoxyethylene poly-oxygen propylene aether sulfate 8g, xanthans 0.15g, ethylene glycol 5g, silica ethane 0.10g, aluminium-magnesium silicate 0.5g, complement to 100g with water, are made in the presence of sand mill Active ingredient weight percentage is 20% fluoxastrobin folpet suspending agent.
Embodiment 6:
Weigh folpet 20g, fluoxastrobin 30g, lignin 5g, polyoxyethylene poly-oxygen propylene aether sulfate 4g, xanthans 0.15g, ethylene glycol 5g, silica ethane 0.10g, aluminium-magnesium silicate 0.5g, complement to 100g with water, are made in the presence of sand mill Active ingredient weight percentage is 50% fluoxastrobin folpet suspending agent.
Embodiment 7:
Weigh folpet 5g, fluoxastrobin 10g, calcium dodecyl benzene sulfonate 10g, phenethyl phenol polyethenoxy ether phosphate 5g, Agriculture breast 33#2g, APES 1g, isopropanol 10g, add water to 100g.Above raw material is routinely prepared into microemulsion Method input mixing kettle in mix, effective Ingredients Weight percentage composition is made for 15% fluoxastrobin folpet microemulsion.
Embodiment 8:
Folpet 30g is weighed, fluoxastrobin 50g, lauryl sodium sulfate 2g, calcium lignosulfonate 3g, kaolin is complemented to 100g.Through coarse crushing and air-flow crushing, then mediated and extruder grain, 80% fluoxastrobin, which is made, through screening after drying goes out Bacterium pellet water dispersible granules.
Field information embodiment 1:The field control effectiveness test of folpet and fluoxastrobin to powdery mildew of cucumber
Test medicine and dosage refer to table 3, often handle 4 repetitions, plot area 20m2, totally 44 cells, random district's groups row Row.Using conventional spray-on process, complete stool is uniformly sprayed, is not dripped for degree with squirting blade.Carried out in powdery mildew of cucumber early stage First time dispenser, carries out second of dispenser after 7 days, separately set clear water and be processed as blank control.State of an illness radix is investigated before dispenser, the With 12 days investigation prevention effects after second of dispenser before secondary dispenser.
Table of field test results is bright:Folpet and fluoxastrobin are applied in combination is better than single dose to the prevention effect of powdery mildew of cucumber, With synergistic effect.
Under this experimental condition, as a result visual observations reagent agent shows to the security of cucumber, and this several medicament is to cucumber Blade is produced without poisoning, performance safety.
Further narration has been done to the present invention above in conjunction with embodiment, but the present invention is not limited to above-mentioned embodiment, In the knowledge that one skilled in the relevant art possesses, it can also be made on the premise of present inventive concept is not departed from Various change.

Claims (7)

1. a kind of Synergistic bactericidal composition, it is characterised in that:Containing folpet and fluoxastrobin, wherein active ingredient folpet with The mass ratio of fluoxastrobin is 1~50: 50~1.
2. bactericidal composition according to claim 1, it is characterised in that:The quality of active ingredient folpet and fluoxastrobin Than for 1~20: 20~1.
3. bactericidal composition according to claim 1, it is characterised in that:The quality of active ingredient folpet and fluoxastrobin Than for 1~10: 10~1.
4. the bactericidal composition according to any one of claim 1-3, it is characterised in that:It can be prepared into what is received on agricultural chemicals Preparation, folpet accounts for the 5%~90% of the whole quality of the pharmaceutical preparations with the gross weight of fluoxastrobin in the formulation.
5. bactericidal composition according to claim 4, it is characterised in that:Folpet and the gross weight of fluoxastrobin in the formulation Amount accounts for the 25%~60% of the whole quality of the pharmaceutical preparations.
6. composition pesticide according to claim 4, it is characterised in that:The formulation of the composition pesticide is missible oil, suspended Agent, wettable powder, water dispersible granules, aqueous emulsion, microemulsion.
7. the bactericidal composition according to any one of claim 1-6 is used for the purposes of controlling plant diseases.
CN201710258727.3A 2017-04-19 2017-04-19 A kind of bactericidal composition containing folpet and fluoxastrobin and application thereof Pending CN107018984A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201710258727.3A CN107018984A (en) 2017-04-19 2017-04-19 A kind of bactericidal composition containing folpet and fluoxastrobin and application thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201710258727.3A CN107018984A (en) 2017-04-19 2017-04-19 A kind of bactericidal composition containing folpet and fluoxastrobin and application thereof

Publications (1)

Publication Number Publication Date
CN107018984A true CN107018984A (en) 2017-08-08

Family

ID=59528117

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201710258727.3A Pending CN107018984A (en) 2017-04-19 2017-04-19 A kind of bactericidal composition containing folpet and fluoxastrobin and application thereof

Country Status (1)

Country Link
CN (1) CN107018984A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108184862A (en) * 2017-12-08 2018-06-22 甄金兰 A kind of Synergistic bactericidal composition
CN108294028A (en) * 2018-03-14 2018-07-20 广东广康生化科技股份有限公司 A kind of bactericidal composition containing Pyriofenone and folpet

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101039578A (en) * 2004-10-12 2007-09-19 拜尔农作物科学股份公司 Fungicidal active ingredient combinations containing fluoxastrobin
CN104094943A (en) * 2014-06-13 2014-10-15 广东中迅农科股份有限公司 Bactericidal composition containing fluoxastrobin and triflumizole

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101039578A (en) * 2004-10-12 2007-09-19 拜尔农作物科学股份公司 Fungicidal active ingredient combinations containing fluoxastrobin
CN104094943A (en) * 2014-06-13 2014-10-15 广东中迅农科股份有限公司 Bactericidal composition containing fluoxastrobin and triflumizole

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108184862A (en) * 2017-12-08 2018-06-22 甄金兰 A kind of Synergistic bactericidal composition
CN108294028A (en) * 2018-03-14 2018-07-20 广东广康生化科技股份有限公司 A kind of bactericidal composition containing Pyriofenone and folpet

Similar Documents

Publication Publication Date Title
CN104886070B (en) Bactericidal composition and application thereof
CA2985520C (en) A pesticide composition comprising tebuconazole and jinggangmycin for preventing and controlling fusarium head blight, and a method wherein the pesticide composition is applied to cultivated grain crops
CN102696622A (en) Pesticide composition capable of preventing and controlling plant disease
CN105961402B (en) A kind of bactericidal composition and its application of jinggangmeisu and triticonazole
CN105010357B (en) Bactericidal composition and its application
CN103053561A (en) Benthiavalicarb isopropyl containing bactericidal composition
CN107018984A (en) A kind of bactericidal composition containing folpet and fluoxastrobin and application thereof
CN106259368B (en) A kind of corn field mixed herbicide containing isoxaflutole
CN104542585A (en) Fungicide composition and application thereof
CN108207985A (en) A kind of rice terrace ternary weeding composition
CN103081920B (en) Sterilizing composition containing penconazole
CN106689148A (en) Pesticide composition containing dichloroxazole and dimethomorph
CN106135232B (en) bactericidal composition
US20190116790A1 (en) Jinggangmycin and Ipconazole Fungicidal Composition and Applications Thereof
CN101953347A (en) Pesticide composition and application thereof
CN109548787A (en) A kind of bactericidal composition and its application
CN105052955B (en) A kind of disinfection and deinsectization composition and suspending agent thereof containing fluoxastrobin
CN108477192A (en) A kind of efficient bactericidal composite containing folpet and hexaconazole
CN103070175B (en) Compound pesticide containing boscalid and kasugamycin and application of compound pesticide
CN107318868A (en) Bactericidal composition comprising folpet and benzene metsulfovax
CN108782578A (en) Composition pesticide containing folpet and fluorine azoles bacterium aniline
CN102939975B (en) Sterilization composition containing triflumizole and dimethomorph and application thereof
CN102349522B (en) Synergy sterilizing composition containing tetraconazole and tricyclazole
CN108184862A (en) A kind of Synergistic bactericidal composition
CN108812677A (en) A kind of composition pesticide of second containing pheno mycin and lentinan

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication
RJ01 Rejection of invention patent application after publication

Application publication date: 20170808