CN103355309B - Sterilization composition and preparation thereof - Google Patents
Sterilization composition and preparation thereof Download PDFInfo
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- CN103355309B CN103355309B CN201310316085.XA CN201310316085A CN103355309B CN 103355309 B CN103355309 B CN 103355309B CN 201310316085 A CN201310316085 A CN 201310316085A CN 103355309 B CN103355309 B CN 103355309B
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- Prior art keywords
- tetraconazole
- oxygen quinoline
- powdery mildew
- bactericidal composition
- bactericide
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- BSYVTEYKTMYBMK-UHFFFAOYSA-N tetrahydrofurfuryl alcohol Chemical compound OCC1CCCO1 BSYVTEYKTMYBMK-UHFFFAOYSA-N 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- QGHREAKMXXNCOA-UHFFFAOYSA-N thiophanate-methyl Chemical group COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC QGHREAKMXXNCOA-UHFFFAOYSA-N 0.000 description 1
- 231100000820 toxicity test Toxicity 0.000 description 1
- 229940126680 traditional chinese medicines Drugs 0.000 description 1
- FFSJPOPLSWBGQY-UHFFFAOYSA-N triazol-4-one Chemical compound O=C1C=NN=N1 FFSJPOPLSWBGQY-UHFFFAOYSA-N 0.000 description 1
- STCOOQWBFONSKY-UHFFFAOYSA-N tributyl phosphate Chemical compound CCCCOP(=O)(OCCCC)OCCCC STCOOQWBFONSKY-UHFFFAOYSA-N 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 description 1
- 229920002554 vinyl polymer Polymers 0.000 description 1
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- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention relates to the field of pesticides preparations, and discloses a sterilization composition and a preparation thereof. The sterilization composition consists of tetraconazole and proquinazid with a weight ratio of 1 : (0.2-10), has substantial synergy effect, and is capable of effectively controlling powdery mildew of multiple crops, reducing the content of the pesticides and delaying generation of drug resistance. A bactericide of the invention is prepared from the sterilization composition, an auxiliary agent and a carrier, and is capable of effectively controlling powdery mildew of multiple crops, especially wheat powdery mildew and cucumber powdery mildew.
Description
Technical field
The present invention relates to technical field of pesticide, relate to a kind of bactericidal composition and preparation thereof specifically, particularly relate to bactericidal composition and preparation thereof that a kind of active component is made up of tetraconazole and the third oxygen quinoline.
Background technology
Powdery mildew is the Common Diseases on crops, all can occur from seedling to strain, blade of mainly causing harm, the climing and petiole of stem of sometimes also causing harm.When just falling ill, there is white fleck in blade face, after expand gradually, finally can be linked to be sheet, blade face be covered with the mould layer of white powder.Time serious, blade turns yellow gradually, withered dead, sometimes scab occurs many black pointing object.Powdery mildew has a strong impact on photosynthesis, and eubolism is interfered, and causes early ageing or output to incur loss.As wheat powdery mildew occurs general in China wheat belt, its harm mainly reduces grain number per spike and reduces thousand kernel weight, and general popular time wheatland underproduction 5%-10%, can the underproduction 30% time serious.Since the later stage seventies, along with of short stem, the popularization of semi-dwarf mutant wheat breed and the improvement of fertilizer and water condition, wheat plant is tillered and has increased, grown densely, cause that field is strongly fragrant covers, it occurs and harm is on the rise, and becomes one of Major Diseases in current Wheat Production.
The kind of powdery mildew is a lot, comprise the powdery mildew of wheat and barley of the wheat classes such as harm barley, rye, oat, the cucurbits powdery mildew that harm cucumber, muskmelon etc. is melon, the beans powdery mildew of the beans such as harm cowpea, pea, broad bean, French beans, Kidney bean, the flowers powdery mildew of the multiple ornamental plants such as harm Chinese rose, crape myrtle, spindle tree, smoke tree, Chinese photinia, winged euonymus, the traditional Chinese medicine powdery mildew of the traditional Chinese medicines such as harm Schisandra sphenanthera Rehd.et WilS, Radix Angelicae Sinensis, the Radix Astragali, matrimony vine, pseudo-ginseng.Comprise powdery mildew of strawberry, grape powdery mildew, mango powdery mildew, apple mildew, eggplant powdery mildew etc. in addition.
The kind of current powdery mildew is different, and prevention and controls is different.As powdery mildew of cucumber sprays thiophanate methyl wetting powder 1000 times of liquid or 75% tpn wetting powder, 500 ~ 600 times of liquid or 56% Fluoxastrobin tpn, 600 times of liquid of 50%.And the prevention and controls of wheat powdery mildew is sprinkling 20% triazolone missible oil 1000 times of liquid or 40% lucky star missible oil, 8000 times of liquid.Adopt Same Way control variety classes powdery mildew, control efficiency is poor.Therefore, develop and all have the bactericide of obvious bactericidal effect significant to the powdery mildew of various crop.
Summary of the invention
In view of this, the object of the invention is to provide a kind of bactericidal composition and preparation thereof, and bactericidal composition provided by the invention all has obvious bactericidal effect to the powdery mildew of various crop.
The invention provides a kind of bactericidal composition, be made up of tetraconazole and the third oxygen quinoline, the weight ratio of described tetraconazole and the third oxygen quinoline is 1:(0.2 ~ 10).
Tetraconazole, English common name tetraconazole, chemical name 2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl) propyl group 1,1,2,2-tetrafluoro ethyl ether, structural formula is such as formula shown in I.Tetraconazole is sterol demethylation inhibitors, owing to having absorption well, therefore can promptly be absorbed by plants, and in conducted inside, there is well protection and therapeutic activity, 6 weeks lasting periods, Erysiphe can be prevented and treated, Puccinia, Rhynchosporium spp．, nuclear cavity Pseudomonas and the microbial disease of Septoria are as wheat powdery mildew, loose smut of wheat, wheat rust, the bunt of wheat, the blessing of wheat grain husk is sick, barley leaf blotch, loose smut of barley, barley banded sclerotial blight, maize head smut, head smut of sorghum, melon and fruit powdery mildew, sigatoka, alternaria leaf spot of apple, pear scab etc.
Third oxygen quinoline, the iodo-2-propoxyl group of English common name proquinazid, chemical name 6--3-propyl group quinazoline-4(3H)-one, molecular formula C
14h
17iN
2o
2, structural formula is such as formula shown in II.Be mainly used in preventing and treating the diseases such as powdery mildew.
Tetraconazole is different with the third oxygen quinoline structure, the mechanism of action is different, and the bactericidal composition be made up of tetraconazole and the third oxygen quinoline can prevent and treat the powdery mildew of various crop simultaneously, creates obvious synergistic effect compared with single dose, there is obvious bactericidal effect, reduce the consumption of agricultural chemicals.
After different bactericidal active constituent mixing, each active component is due to the difference of composition, structure, physicochemical property, makes the synergy between each active component be typically expressed as synergistic effect, summation action or antagonism.So-called synergistic effect is exactly the mutual synergism between different material, and its effect produced is greater than the sum total of each composition effect; And summation action is exactly the sum total that its effect produced equals each composition effect; When antagonism refers to that two kinds of materials act on living organism, a kind of material disturbs the effect of another kind of material, or the effect of interfering with an opponent each other, makes the phenomenon that general effect declines.
The present invention evaluates two kinds of mixed interactions of different activities component of the present invention with reference to Sun Yunpei (Sun YP) method, and wherein, co-toxicity coefficient (CTC) >=120 shows as synergistic effect; Co-toxicity coefficient (CTC)≤80 shows as antagonism; 80< co-toxicity coefficient (CTC) <120 shows as summation action.The present invention by calculate tetraconazole mixed with the third oxygen quinoline after co-toxicity coefficient, effect after both evaluations are mixed, result shows, and the weight ratio of described tetraconazole and the third oxygen quinoline is 1:(0.2 ~ 10) co-toxicity coefficient be all greater than 120.Found by the test of outdoor biological activity determination, the weight ratio of described benzene tetraconazole and the third oxygen quinoline is 1:(0.2 ~ 10) ratio used in combination there is notable synergistic effect.
As preferably, in bactericidal composition provided by the invention, the weight ratio of tetraconazole and the third oxygen quinoline is 1:(0.2 ~ 10).
Preferably, in bactericidal composition provided by the invention, the weight ratio of tetraconazole and the third oxygen quinoline is 1:1:(1 ~ 3).
Pesticide original medicine can not directly use, and must process and be mixed with various pesticidal preparations, could use.Therefore the present invention also provides a kind of bactericide, is made up of bactericidal composition of the present invention and auxiliary agent and carrier/solvent.
Wherein, the percentage by weight accounting for described bactericide as preferred described bactericidal composition is 1% ~ 80%, is 20% ~ 80% in certain embodiments.Be 10% ~ 50% in certain embodiments.
Insecticide of the present invention as required according to method known in those skilled in the art, can make pesticidal preparations by Pesticidal combination of the present invention and auxiliary agent, to be applied to agricultural production.As missible oil, aqueous emulsion, wetting powder, water dispersible granules can be mixed with according to method known to those skilled in the art.
As preferably, weed killer herbicide of the present invention is missible oil.Bactericidal composition of the present invention accounts for the weight ratio of described missible oil is in certain embodiments 20% ~ 80%, and the weight ratio that emulsifier accounts for described missible oil is 1% ~ 20%, surplus is solvent.
As preferably, weed killer herbicide of the present invention is aqueous emulsion.Bactericidal composition of the present invention accounts for the weight ratio of described aqueous emulsion is in certain embodiments 1%-50%, the weight ratio that solvent accounts for described aqueous emulsion is 0-15%, the weight ratio that emulsifier accounts for described aqueous emulsion is 1-30%, the weight ratio that co-emulsifier accounts for described aqueous emulsion is 0.2% ~ 5.0%, the weight ratio that thickener accounts for described aqueous emulsion is 0-5%, the weight ratio that antifreeze accounts for described aqueous emulsion is 0-2%, and surplus is water.
As preferably, weed killer herbicide of the present invention is wetting powder.Bactericidal composition of the present invention accounts for the weight ratio of described wetting powder is in certain embodiments 1% ~ 80%, and the weight ratio that wetting agent accounts for described wetting powder is 1% ~ 7%, and the weight ratio that dispersant accounts for described wetting powder is 2% ~ 10%, and surplus is carrier.
As preferably, weed killer herbicide of the present invention is water dispersible granules.Bactericidal composition of the present invention accounts for the weight ratio of described water dispersible granules is in certain embodiments 1% ~ 80%, the weight ratio that wetting agent accounts for described water dispersible granules is 1% ~ 7%, the weight ratio that dispersant accounts for described water dispersible granules is 2% ~ 10%, the weight ratio that disintegrant accounts for described water dispersible granules is 0 ~ 5%, the weight ratio that adhesive accounts for described water dispersible granules is 0 ~ 1%, and surplus is carrier.
The auxiliary agent such as emulsifier, co-emulsifier, wetting agent, solvent, antifreeze, thickener, disintegrant, adhesive, carrier that more than preparation various preparation is used is and well known to a person skilled in the art.
Preferably, emulsifier of the present invention is selected from peaceful newborn 33#(styryl fluosite PULLRONIC F68 block type polyethers), peaceful newborn 34(styrene phenol formaldehyde resin polyoxyethylene poly-oxygen propylene aether), peaceful newborn 37(styrylphenol formaldehyde resin APEO), peaceful newborn 700(benzene second camphor tree (or ɑ-methyl styrene) phenol formaldehyde resin APEO), calcium dodecyl benzene sulfonate (agriculture breast 500), the compound (agriculture breast 0201B) of anion and non-ionic surface active agent solvent, agriculture breast 0203B, alkyl phenol formaldehyde resin polyoxyethylene ether (Nongru-700), alkylphenol-polyethenoxy (15) ether (agriculture breast NP-15), phenethyl phenol polyethenoxy polyethenoxy ether (agriculture breast 1601), castor oil polyoxyethylene ether (agriculture breast BY110), alkyl phenyl polyethylene oxides ether (agriculture breast 100), sorbitan monooleate (S-80), dibutyl naphthalenesulfonic acid calcium (agriculture breast 2201), castor oil polyoxyethylene (40) ether (agriculture breast EL-40), one or more in Tween-20 (agriculture breast T-20) and alkyl vinyl aryl phenyl ether (YUS-SC3), co-emulsifier is selected from one or more in butanols, isobutanol, dodecanol-1, tetradecanol-1, octadecanol-1, nonadecanol-1, eicosanol-1.
Preferably, wetting agent of the present invention be selected from TERWET1004, SP-2845W, MorwetEFW, pull open in powder, lauryl sodium sulfate, dodecyl sodium naphthalene sulfonate, neopelex, calcium dodecyl benzene sulfonate and penetrating agent JFC one or more; Described dispersant can be selected from one or more in MorwetD-425, Morwet D-500, SP-2836, TERSPERSE 2700, TERSPERSE 2425, DEHSCOFIX920, sodium methylene bis-naphthalene sulfonate, dispersing agent MF, sodium lignin sulfonate, calcium lignosulfonate and carboxymethyl cellulose.
Preferably, solvent of the present invention is selected from one or more in aromatic solvent naphtha, tributyl phosphate, tetrahydrofurfuryl alcohol, oxolane, vegetable oil, paraffin oil, lubricating oil, No. 100, solvent naphtha, No. 150, solvent naphtha, No. 180, solvent naphtha and No. 200, solvent naphtha.
Preferably, antifreeze of the present invention is selected from ethylene glycol, propane diols, glycerine, hexylene glycol, urea, ammonium sulfate, NaCl, CaCl
2in one or more.
Preferably, thickener of the present invention is selected from one or more in Sodium Polyacrylate, cellulose derivatives, xanthans, mineral clay, polyvinyl alcohol and gum Arabic.
Preferably, disintegrant of the present invention be selected from urea, sodium carboxymethylcellulose, ammonium sulfate, silica gel, PEG and SF-04 in one or more one or more.
Preferably, adhesive of the present invention is selected from one or more in sucrose, soluble starch, Sodium Polyacrylate, dextrin, xanthans and organobentonite.
Preferably, carrier of the present invention can be selected from one or more in kaolin, bentonite, potter's clay, diatomite, white carbon and precipitated calcium carbonate.
Bactericide of the present invention effectively can prevent and treat the various crop such as wheat powdery mildew, powdery mildew of cucumber white powder disease, has obvious synergistic effect compared with single dose.Therefore present invention also offers the application of above-mentioned bactericide in control crop powdery mildew evil.Wherein, as preferably, described crop powdery mildew evil is wheat powdery mildew, powdery mildew of cucumber.
Bactericidal composition of the present invention is made up of tetraconazole and the third oxygen quinoline, the weight ratio of described tetraconazole and the third oxygen quinoline is 1:(0.2 ~ 10), there is obvious synergistic effect, effectively can prevent and treat various crop white powder disease, reduce the consumption of agricultural chemicals, and drug-fast generation can be delayed.Bactericide of the present invention is made up of described bactericidal composition and auxiliary agent and carrier, effectively can prevent and treat various crop white powder disease, especially wheat powdery mildew, powdery mildew of cucumber.
Embodiment
The invention provides a kind of bactericidal composition and preparation thereof, those skilled in the art can use for reference present disclosure, and suitable improving technique parameter realizes.Special needs to be pointed out is, all similar replacements and change apparent to those skilled in the art, they are all deemed to be included in the present invention.Method of the present invention and application are described by preferred embodiment, related personnel obviously can not depart from content of the present invention, spirit and scope methods and applications as herein described are changed or suitably change with combination, realize and apply the technology of the present invention.
In order to understand the present invention further, below in conjunction with embodiment, a kind of bactericidal composition provided by the invention and preparation thereof are described in detail.
The Toxicity Determination of embodiment 1, bactericidal composition of the present invention
In order to screen tetraconazole and the composite ratio of the third oxygen quinoline, carry out Toxicity Determination with the tetraconazole third oxygen quinoline of different ratio.Test adopts pot-culture method to carry out toxicity test.Measure the virulence of tetraconazole and the third oxygen quinoline single dose respectively simultaneously.
Tetraconazole single dose concentration for the treatment of is 6,4,3,2,1.6 μ g/mL, third oxygen quinoline single dose concentration for the treatment of is 36,18,9,4.5,2.25 μ g/mL, the test of combination medicament also arranges 5 concentration gradients, separately establishes the blank of not dosing, and each process repeats for 4 times.
Select susceptible cucumber variety potted plant, treat that seedling grows to the two panels few leaf open and flat phase for subsequent use.With the pure water being added with a small amount of Tween-80, wash the Fresh spores got and cover with on Powdery Mildew plant leaf blade, filter with double gauze, making spore concentration is 1 × 10
5the suspension of individual spore/mL, for subsequent use.Liquid is evenly sprayed in blade face to all moistening, for subsequent use after liquid natural air drying.Use spore suspension spray inoculation.24h inoculation before chemicals treatment.Postvaccinal examination material natural air drying, then moves to thermostatic chamber, under the condition of temperature 20 DEG C-24 DEG C, cultivate 7d-10d.According to medicine inspecting institute of the Ministry of Agriculture " farm-chemical indoor determination test rule " method, when the sick leaf rate of blank reaches more than 80%, classification investigation manages incidence everywhere, often processes and at least investigates 30 leaves.Calculate disease index and the control efficiency of each process.Do regression analysis according to each drug concentration logarithm value and preventive effect probability value, calculate the EC of each medicament
50.
After different fungicidal activity component mixing, each active component is due to the difference of composition, structure, physicochemical property, makes the synergy between each active component be typically expressed as synergistic effect, summation action or antagonism.So-called synergistic effect is exactly the mutual synergism between different material, and its effect produced is greater than the sum total of each composition effect; And summation action is exactly the sum total that its effect produced equals each composition effect; When antagonism refers to that two kinds of materials act on living organism, a kind of material disturbs the effect of another kind of material, or the effect of interfering with an opponent each other, makes the phenomenon that general effect declines.
Co-toxicity coefficient (CTC) >=120 shows as synergistic effect;
Co-toxicity coefficient (CTC)≤80 shows as antagonism;
80< co-toxicity coefficient (CTC) <120 shows as summation action.
Actual measurement toxicity index (ATI)=(standard agent EC
50/ reagent agent EC
50) × 100
Theoretical toxicity index (the TTI)=percentage composition of A (in the toxicity index × mixture of the A)+percentage composition of B (in the toxicity index × mixture of B)
Co-toxicity coefficient (CTC)=[theoretical virulence coefficient (TTI) of mixture actual measurement virulence coefficient (ATI)/mixture] × 100
The Toxicity Determination result of bactericidal composition provided by the invention to cucumber powdery mildew's pathogen is as shown in table 1.
Table 1 tetraconazole third oxygen quinoline is to the recipe determination result of powdery mildew of cucumber germ
From table 1, tetraconazole and the third oxygen quinoline mixture, part by weight scope is in 1:(0.2 ~ 10) between its co-toxicity coefficient all more than 120, illustrate that tetraconazole and the third oxygen quinoline carry out composite under this ratio, good synergistic effect can be produced compared with single dose.
Use the same method and do tetraconazole and the third oxygen quinoline is tested the co-toxicity of wheat powdery mildew, the results are shown in Table 2.
Table 2 tetraconazole third oxygen quinoline is to the recipe determination result of wheat powdery mildew germ
From table 1 and 2, bactericidal composition provided by the invention to the control efficiency of wheat powdery mildew, powdery mildew of cucumber compared with single dose, be significantly increased, thus further illustrate bactericidal composition provided by the invention and effectively can prevent and treat various crop white powder disease, obvious synergistic effect is created compared with single dose, the consumption of agricultural chemicals can be reduced, thus reduce production cost and save labour.
Embodiment 2,20% tetraconazole third oxygen quinoline missible oil
Tetraconazole 15%, third oxygen quinoline 5%, agriculture breast 0203B5%, No. 100, solvent naphtha supply 100%.By tetraconazole, the third oxygen quinoline, emulsifier, solvent naphtha through abundant mixed grinding, to obtain final product.
Embodiment 3,48% tetraconazole third oxygen quinoline missible oil
Tetraconazole 40%, third oxygen quinoline 8%, agriculture breast 22015%, Nongru-700 10%, oxolane supply 100%.By tetraconazole, the third oxygen quinoline, emulsifier, solvent naphtha through abundant mixed grinding, to obtain final product.
Embodiment 4,64% tetraconazole third oxygen quinoline missible oil
Tetraconazole 8%, third oxygen quinoline 56%, peaceful breast 70020%, paraffin oil supply 100%.By tetraconazole, the third oxygen quinoline, emulsifier, solvent naphtha through abundant mixed grinding, to obtain final product.
Embodiment 5,80% tetraconazole third oxygen quinoline missible oil
Tetraconazole 10%, third oxygen quinoline 70%, peaceful breast 3715%, Nongru-700 3%, No. 200, solvent naphtha supply 100%.By tetraconazole, the third oxygen quinoline, emulsifier, solvent naphtha through abundant mixed grinding, to obtain final product.
Embodiment 6,1% tetraconazole third oxygen quinoline aqueous emulsion
Tetraconazole 0.5%, third oxygen quinoline 0.5%, peaceful breast 3725%, solvent naphtha No. 100 10%, butanols 1%, hexylene glycol 2%, PAA 3%, water are less than 100%.Tetraconazole, the third oxygen quinoline, butanols, peaceful breast 37, No. 100, solvent naphtha are mixed into homogeneous oil phase; Ethylene glycol, PAA, water are mixed into homogeneous aqueous phase; Aqueous phase is joined in oil phase, shears through high-speed shearing machine and get final product.
Embodiment 7,27% tetraconazole third oxygen quinoline aqueous emulsion
Tetraconazole 9%, third oxygen quinoline 18%, agriculture breast NP-1530%, tetradecanol-11%, solvent naphtha No. 150 5%, hexylene glycol 1.5%, mineral clay 2%, water supply 100%.Tetraconazole, the third oxygen quinoline, agriculture breast NP-15, tetradecanol-1%, No. 150, solvent naphtha are mixed into homogeneous oil phase; Hexylene glycol, mineral clay, water are mixed into homogeneous aqueous phase; Aqueous phase is joined in oil phase, shears through high-speed shearing machine and get final product.
Embodiment 8,33% tetraconazole third oxygen quinoline aqueous emulsion
Tetraconazole 3%, third oxygen quinoline 30%, peaceful breast 342%, butanols 5%, paraffin oil 5%, ammonium sulfate 2%, gum Arabic 5%, water supply 100%.Tetraconazole, the third oxygen quinoline, peaceful breast 34, butanols, paraffin oil are mixed into homogeneous oil phase; Ammonium sulfate, gum Arabic, water are mixed into homogeneous aqueous phase; Aqueous phase is joined in oil phase, shears through high-speed shearing machine and get final product.
Embodiment 9,50% tetraconazole third oxygen quinoline aqueous emulsion
Tetraconazole 10%, third oxygen quinoline 40%, peaceful breast 70025%, isobutanol 2%, solvent naphtha No. 180 5%, hexylene glycol 0.5%, xanthans 2%, water supply 100%.Tetraconazole, the third oxygen quinoline, peaceful breast 700, isobutanol, solvent naphtha 180 are mixed into homogeneous oil phase; Hexylene glycol, xanthans, water are mixed into homogeneous aqueous phase; Aqueous phase is joined in oil phase, shears through high-speed shearing machine and get final product.
Embodiment 10,1% tetraconazole third oxygen quinoline wetting powder
Tetraconazole 0.8%, third oxygen quinoline 0.2%, pull open powder 3%, calcium lignosulfonate 6%, kaolin supplies 100%.By tetraconazole, the third oxygen quinoline, wetting agent, dispersant and carrier, through air-flow crushing, fully mix, to obtain final product.
Embodiment 11,35% tetraconazole third oxygen quinoline wetting powder
Tetraconazole 5%, third oxygen quinoline 30%, pull open powder 2%, sodium lignin sulfonate 5%, diatomite supplies 100%.By tetraconazole, the third oxygen quinoline, wetting agent, dispersant and carrier, through air-flow crushing, fully mix, to obtain final product.
Embodiment 12,63% tetraconazole third oxygen quinoline wetting powder
Tetraconazole 9%, third oxygen quinoline 54%, moistening penetrant t 3%, carboxymethyl cellulose 7%, precipitated calcium carbonate supply 100%.By tetraconazole, the third oxygen quinoline, wetting agent, dispersant and carrier, through air-flow crushing, fully mix, to obtain final product.
Embodiment 13,80% tetraconazole third oxygen quinoline wetting powder
Tetraconazole 8%, third oxygen quinoline 72%, Morwet EFW2%, Morwet D-4254%, bentonite supply 100%.By tetraconazole, the third oxygen quinoline, wetting agent, dispersant and carrier, through air-flow crushing, fully mix, to obtain final product.
Embodiment 14,1% tetraconazole third oxygen quinoline water dispersible granules
Tetraconazole 0.2%, third oxygen quinoline 0.8%, TERWET 1,004 1%, TERSPERSE24253%, kaolin supply 100%.By tetraconazole, the third oxygen quinoline, wetting agent, dispersant and carrier, through air-flow crushing, fully mixing, mediate granulation, drying and screening, to obtain final product.
Embodiment 15,42% tetraconazole third oxygen quinoline water dispersible granules
Tetraconazole 14%, third oxygen quinoline 28%, pull open powder 5%, sodium lignin sulfonate 10%, ammonium sulfate 1%, xanthans 1%, precipitated calcium carbonate supply 100%.By tetraconazole, the third oxygen quinoline, wetting agent, dispersant, disintegrant, adhesive and carrier, through air-flow crushing, fully mixing, mediate granulation, drying and screening, to obtain final product.
Embodiment 16,72% tetraconazole third oxygen quinoline water dispersible granules
Tetraconazole 8%, third oxygen quinoline 64%, SP-2845W 2%, SP-2836 5%, bentonite supply 100%.By tetraconazole, the third oxygen quinoline, wetting agent, dispersant and carrier, through air-flow crushing, fully mixing, mediate granulation, drying and screening, to obtain final product.
Embodiment 17,80% tetraconazole third oxygen quinoline water dispersible granules
Tetraconazole 40%, third oxygen quinoline 40%, dodecyl sodium naphthalene sulfonate 4%, dispersing agent MF 8%, PEG2%, soluble starch 0.5%, precipitated calcium carbonate supply 100%.By tetraconazole, the third oxygen quinoline, wetting agent, dispersant, disintegrant, adhesive and carrier, through air-flow crushing, fully mixing, mediate granulation, drying and screening, to obtain final product.
The explanation of above embodiment just understands method of the present invention and core concept thereof for helping.It should be pointed out that for those skilled in the art, under the premise without departing from the principles of the invention, can also carry out some improvement and modification to the present invention, these improve and modify and also fall in the protection domain of the claims in the present invention.
Claims (6)
1. a bactericidal composition, is characterized in that, is made up of tetraconazole and the third oxygen quinoline, and the weight ratio of described tetraconazole and the third oxygen quinoline is 1:5 ~ 10:1.
2. bactericidal composition according to claim 1, is characterized in that, the weight ratio of described tetraconazole and the third oxygen quinoline is 1:(1 ~ 3).
3. a bactericide, is characterized in that, is made up of bactericidal composition described in claim 1 or claim 2 and auxiliary agent and carrier.
4. bactericide according to claim 3, it is characterized in that, the percentage by weight that described bactericidal composition accounts for described bactericide is 1% ~ 80%.
5. bactericide according to claim 4, is characterized in that, the formulation of described bactericide is missible oil, aqueous emulsion, wetting powder, water dispersible granules.
6. the application of any one bactericide described in claim 3-5 in control crop powdery mildew.
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| CN106577674A (en) * | 2016-12-02 | 2017-04-26 | 西安北农华农作物保护有限公司 | Fungicidal composition containing proquinazid |
Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003104811A (en) * | 2001-09-27 | 2003-04-09 | Sumitomo Chem Co Ltd | Bactericidal composition and method for preventing disease of crop |
| CN101700032A (en) * | 2009-11-30 | 2010-05-05 | 青岛星牌作物科学有限公司 | Bactericidal composition containing thiabendazole and application thereof |
| CN101731238A (en) * | 2009-12-23 | 2010-06-16 | 深圳诺普信农化股份有限公司 | Acibenzolar-containing sterilizing composition |
| CN101779674A (en) * | 2009-12-16 | 2010-07-21 | 陈章艳 | Sterilization composition containing tetraconazole |
| CN101822255A (en) * | 2010-01-27 | 2010-09-08 | 深圳诺普信农化股份有限公司 | Sterilization compound containing ZJ0712 |
| WO2010115793A2 (en) * | 2009-04-07 | 2010-10-14 | Basf Se | Method of protecting grapevines against grapevine yellow disease |
| WO2011073103A1 (en) * | 2009-12-16 | 2011-06-23 | Bayer Cropscience Ag | Active compound combinations comprising proquinazid, bixafen and/or prothioconazole |
| CN102150660A (en) * | 2010-12-16 | 2011-08-17 | 陕西韦尔奇作物保护有限公司 | Sterilization composition containing tetraconazole |
| CN102349514A (en) * | 2011-10-11 | 2012-02-15 | 海利尔药业集团股份有限公司 | Bupirimate-containing antibacterial composition |
-
2013
- 2013-07-25 CN CN201310316085.XA patent/CN103355309B/en not_active Expired - Fee Related
Patent Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003104811A (en) * | 2001-09-27 | 2003-04-09 | Sumitomo Chem Co Ltd | Bactericidal composition and method for preventing disease of crop |
| WO2010115793A2 (en) * | 2009-04-07 | 2010-10-14 | Basf Se | Method of protecting grapevines against grapevine yellow disease |
| CN101700032A (en) * | 2009-11-30 | 2010-05-05 | 青岛星牌作物科学有限公司 | Bactericidal composition containing thiabendazole and application thereof |
| CN101779674A (en) * | 2009-12-16 | 2010-07-21 | 陈章艳 | Sterilization composition containing tetraconazole |
| WO2011073103A1 (en) * | 2009-12-16 | 2011-06-23 | Bayer Cropscience Ag | Active compound combinations comprising proquinazid, bixafen and/or prothioconazole |
| CN101731238A (en) * | 2009-12-23 | 2010-06-16 | 深圳诺普信农化股份有限公司 | Acibenzolar-containing sterilizing composition |
| CN101822255A (en) * | 2010-01-27 | 2010-09-08 | 深圳诺普信农化股份有限公司 | Sterilization compound containing ZJ0712 |
| CN102150660A (en) * | 2010-12-16 | 2011-08-17 | 陕西韦尔奇作物保护有限公司 | Sterilization composition containing tetraconazole |
| CN102349514A (en) * | 2011-10-11 | 2012-02-15 | 海利尔药业集团股份有限公司 | Bupirimate-containing antibacterial composition |
Non-Patent Citations (1)
| Title |
|---|
| 四氟醚唑对黄瓜的安全性及其对黄瓜白粉病的防治效果;于春雷等;《植物保护学报》;20120630;第39卷(第3期);265-270 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT201900013446A1 (en) * | 2019-07-31 | 2021-01-31 | Isagro Spa | LIQUID AGROCHEMICAL MIXTURE CONTAINING TETRACONAZOLE AND RELATIVE USE AS FUNGICIDE IN AGRICULTURAL CROPS. |
| WO2021019452A1 (en) * | 2019-07-31 | 2021-02-04 | Isagro S.P.A. | Agrochemical liquid mixture containing tetraconazole and relative use as fungicide in agricultural crops |
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