CN105191946A - Sterilization composition and application thereof - Google Patents
Sterilization composition and application thereof Download PDFInfo
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- CN105191946A CN105191946A CN201510564623.6A CN201510564623A CN105191946A CN 105191946 A CN105191946 A CN 105191946A CN 201510564623 A CN201510564623 A CN 201510564623A CN 105191946 A CN105191946 A CN 105191946A
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Abstract
The invention discloses a sterilization composition and application thereof, and relates to the technical field of combination of pesticides. The effective constituents of the sterilization composition provided by the invention are prothioconazole and phenazino-1-carboxylic acid, wherein the weight ratio of the prothioconazole to the phenazino-1-carboxylic acid is 1:30 to 30:1. The combination of the prothioconazole and the phenazino-1-carboxylic acid has obvious synergism, can effectively reduce the application amounts of various mono-agents, has better effect on enlarging a bacteriocidal spectrum and delaying the resistance to drugs of plants, and can prolong the period of preserving effect, and obvious promotional value is realized. Auxiliary elements allowed to be used in other pesticides can be added in the composition to process into any one dosage form. The sterilization composition can effectively control and treat rice sheath blight disease, rice blast, false smut, wheat rust, powdery mildew and the like.
Description
Technical field
The present invention relates to a kind of microbicide compositions and application thereof, refer to a kind of be active ingredient microbicide compositions and the application thereof of prothioconazoles and Shen piperazine mycin especially, belong to technical field of compounded pesticide.
Background technology
In agricultural production, can crops healthy growth, except affecting by worm, crop smothering, also very important to the control of disease.Along with reinforcement and the sustainable development implementation of environmental protection ideas, the inexorable trend efficient, low toxicity, high activity, low-residual have become Agrochemicals.But, even if efficient germicide, be used alone for a long time, also easily make disease develop immunity to drugs, cause the problems such as dosage increasing, preventive effect reduction, lasting period shortening, be unfavorable for environment sustainable development.Therefore, how Scientific Usage of Drugs, reduces the consumption of chemical pesticide, improves drug effect, becomes the problem that plant protection art is badly in need of solving.
Prothioconazoles, structure, such as formula shown in (I), is the New-type wide-spectrum triazolinthione series bactericidal agent of Beyer Co., Ltd's exploitation in 2004.Compared with triazole bactericidal agent, have the bactericidal activity of wide spectrum more, topmost application crop is cereal, rape and peanut.Prothioconazoles almost has good preventive effect to all diseases of wheat class, as powdery mildew, banded sclerotial blight, fusarium wilt, leaf spot, rust, stalk break, net blotch, moire disease etc., particularly has special activity to banded sclerotial blight and spot blight.The mechanism of action of prothioconazoles is the demethylation effect on the precursor-lanosterol of sterol in Antifungi or 2,4-methylene lanostenol 14, i.e. demethylation inhibitors (DMIs).Not only there is good systemic activity, the activity of excellent protection, treatment, elimination, and the lasting period is long.Due to single dose Long-Time Service, treatment target has produced very strong pesticide resistance, causes drug effect to reduce, and the lasting period shortens.
Shen piperazine mycin, its structural formula is as shown in (IV), Shen piperazine mycin is a kind of antibiotic secreted through biological culture by pseudomonas fluorescens M18, has wide spectrum Suppressing phytopathogens and the bactericide of the dual-use function of Promoting plant growth effect simultaneously, has wide spectrum, efficiently feature.
Structural formula (I) prothioconazoles structural formula (II) kasugarnycin
Structural formula (III) polyoxin structural formula (IV) Shen piperazine mycin
Banded sclerotial blight is also known as moire disease, and popular name spends sufficient stalk, rotten pin pest, features spot.Be infected by Rhizoctonia solani Kuhn to fall ill, how occur under high temperature, super-humid conditions.Banded sclerotial blight causes harm seriously in South Rice Region of China, is one of Major Diseases in current Rice Production.This disease makes paddy rice not ear, or the not plump paddy of heading is more, and grain heavily declines.
False smut, calls blue or green powder disease, pseudo-smut, belongs to fungal disease.Along with some popularization of compact water rice varieties of short stem and the raising of Fertilization Level, this sick generation is more and more outstanding.The empty flat grain of sick fringe significantly increases, generally can the underproduction 5% ~ 10% after morbidity.False smut mainly occurs at Rice Heading blooming stage, and harm fringe upper part grain, every fringe 1 ~ 2 at least, serious reaches 20 ~ 30.
Frequent use containing single-activity component bactericide, cause most germs to create pesticide resistance, preventive effect is unsatisfactory.Therefore, be badly in need of the sterilised products that a kind of novel product substitutes single-activity component, increase the resistance risk that drug effect delays disease, reduce economic loss.
Summary of the invention
It is reasonable that the technical problem to be solved in the present invention is to provide a kind of component, and synergistic effect is remarkable, and bactericidal effect is good, and drug cost is low, not easily develops immunity to drugs, to the bactericidal composition of crop safety and application thereof.
For solving the problems of the technologies described above, the invention provides technical scheme as follows:
Bactericidal composition of the present invention, its active ingredient is prothioconazoles and Shen piperazine mycin, and the weight ratio of prothioconazoles and Shen piperazine mycin is 1:30 ~ 30:1, and preferred weight ratio is 1:20 ~ 20:1, and more preferably weight ratio is 1:10 ~ 10:1
Pesticidal preparations auxiliary element can also be contained, to make the formulation being applicable to agriculturally using in bactericidal composition of the present invention.Described pesticidal preparations auxiliary element is one or more in solvent, emulsifier, dispersant, stabilizing agent, antifreezing agent or wetting agent.
Bactericidal composition of the present invention can be prepared into any one formulation of applicable agricultural use by known method, reasonable formulation is dry suspending agent (DF), wetting powder (WP), water dispersible granules (WDG), suspending agent (SC) etc.
A wetting powder (WP) is can homodisperse solid powder preparation in water.Wetting powder of the present invention except adding as white carbon in former medicine, precipitated calcium carbonate, potter's clay, diatomite, outside the thinners such as attapulgite or inert substance, also have ionic or nonionic surface active agent (wetting agent, dispersant), wetting agent is alkylbenzenesulfonate (DBS-Na) such as, alkylnaphthalene sulfonate (pulling open powder), alkylphenol-polyethenoxy base ether sulfate, alkylphenol-polyethenoxy base ether formaldehyde condensation products sulphate, aliphatic alcohol sulfate, fatty alcohol ethylene oxide adduct sulfonate, alkyl amide taurate, aliphatic alcohol polyethenoxy base ether (JFC), content 0.1 ~ 30%, dispersant is as naphthalene sulfonate, naphthalene or alkyl naphthalene formaldehyde condensate sulfonates (NO, NNO, MF), lignin and derivative sulfonate (M-9, POLYFON etc.) thereof, polyoxyethylene poly-oxygen propylene aether block copolymer, alkylphenol-polyethenoxy base ether formaldehyde condensation products sulphate (SOPA), PVA, CMC, content 0.1 ~ 30%, also containing one or more materials among penetrating agent JFC, azone, thiophene ketone, penetrant t, content 0.3 ~ 30%, other auxiliary agents such as stabilizing agent, foam inhibitor, anticaking agent can also be contained.
B water dispersible granules (WDG) very fast disintegration in water, dispersion can form the granule of higher suspension dispersion.Be made up of key elements such as auxiliary agent and carrier such as active component, wetting agent, dispersant, interleaving agent, disintegrant, stabilizing agent, adhesives.Its auxiliary agent and carrier, and the compound method of precursor (preformed objects before granulation) is analogous to wetting powder and suspending agent substantially.
C suspending agent (SC) is not water soluble solid agricultural chemicals or the dispersion of immiscible liquids agricultural chemicals in water or oil.Obtained through soybean dietary fiber by active component, auxiliary agent (wetting dispersing agent, thickener, stabilizing agent, pH adjusting agent, defoamer, antifreezing agent).Wetting dispersing agent can be naphthalene or alkyl naphthalene formaldehyde condensate sulfonates (NO, NNO, MF), lignin and derivative sulfonate (M-9, POLYFON etc.) thereof, alkylphenol-polyethenoxy base ether sulfonate, polyoxyethylene polyoxypropylene base ether block copolymers, one or more in alkylphenol-polyethenoxy base phosphate, carboxymethyl cellulose (CMC), polyvinylpyrrolidone (PVP), polyethylene glycol (PEG), condensed phosphate etc., content 0.1 ~ 12%; Thickener and stabilizing agent can be one or more in xanthan gum (XG), polyvinyl alcohol (PVA), Magnesiumaluminumsilicate etc., content 0.05 ~ 0.5%; PH adjusting agent and defoamer can optionally add in right amount.
D dry suspending agent (DF) very fast disintegration in water, dispersion can form the granule of higher suspension dispersion.Preparation method: to be dewatered the preparation obtained by suspending agent.Its auxiliary agent and carrier, and the compound method of precursor (preformed objects before dehydrating) is consistent with suspending agent.
Compared with prior art, beneficial effect of the present invention is: 1, compared with single dose, and composite have obvious synergistic function, improves control efficiency; 2, composition is made up of the active ingredient that two kinds of mechanism of action are different, and bactericidal effect is good, is conducive to overcoming and delay the drug-fast generation of germ; 3, medicament mixture decreases dosage, thus reduces cost and alleviate the pollution to environment.
Instant component is reasonable, and treatment adds protective effect, and drug cost is low, and its activity and bactericidal effect are not the simple superposition of each composition activity, but has significant synergistic effect, good to crop safety, meets the security requirement of pesticidal preparations.
The present invention has good control efficiency to rice sheath blight disease, rice blast, false smut, wheat rust, powdery mildew etc.
Embodiment
For making the technical problem to be solved in the present invention, technical scheme and advantage clearly, will be described in detail with specific embodiment below, but the present invention is limited to absolutely not these examples.The following stated is only the good embodiment of the present invention, only in order to explain the present invention, therefore can not be interpreted as the restriction to the scope of the claims of the present invention.It should be pointed out that all any amendments done within the spirit and principles in the present invention, equivalent replacement and improvement etc., all should be included within protection scope of the present invention.Therefore, the protection domain of patent of the present invention should be as the criterion with claims.
The combination of active principles of different agricultural chemicals is made agricultural chemicals, is current development novel pesticide and the one of preventing and treating agriculturally resistance germ effectively and efficiently mode.After the pestsides synthesis of different cultivars, usually show roughly three kinds of type of action: summation action, synergistic effect and antagonism.Compound synergic is well filled a prescription, and can significantly improve actual control efficiency, and reducing the usage amount of agricultural chemicals, thus contribute to delaying the drug-fast generation speed of germ, is the important means of integrated control disease.
The present composition with prothioconazoles for a kind of active ingredient (A), Shen piperazine mycin is another active ingredient (E), combine between them, to plant disease, there is obvious synergistic function, and being not only the simple superposition of two kinds of pharmacy effects, this clearly can recognize from following test result.
In order to prevent and treat wheat powdery mildew in agricultural production, inventor, with prothioconazoles and antibiotics bactericide Shen piperazine mycin, has carried out mutual composite synergy research.
Concrete grammar is: test adopts wheat powdery mildew to be tested object.Former medicine is mixed with the test medicine of needs, test method is with reference to " People's Republic of China's agricultural industry criteria ".First single dose and each Mixed Pharmacy are arranged 5 variable concentrations gradients (on the basis of preliminary experiment result, different with proportioning according to different agents combination, concentration arranges also different, and bacteriostasis rate sets in the scope of 5% ~ 95%).If clear water contrasts, repeat 3 times.Adopt live body inoculation method, inoculate in each process, be placed in 25 DEG C of constant temperature and humidity incubators and cultivate 4d; Check that scab accounts for the percentage of inoculation blade, calculate each process and suppress the percentage of lesions grow, by the linear regression analysis between the probit value of inhibiting rate and the logarithm value of series concentration, obtain the EC of each medicament
50value, calculates the co-toxicity coefficient (CTC) of mixture, evaluates the activity of reagent agent to germ with this with co-toxicity coefficient table.
Table 1 prothioconazoles and the composite Toxicity Determination to wheat powdery mildew of Shen piperazine mycin
| Chemicals treatment | Virulence regression equation | EC 50(mg/L) | Co-toxicity coefficient (CTC) |
| Prothioconazoles (A) | Y＝3.2874+1.4235X | 15.9629 | —— |
| Shen piperazine mycin (E) | Y＝2.9108+1.4017X | 30.9357 | —— |
| A：E＝1:30 | Y＝3.0859+1.4069X | 22.9335 | 130.93 |
| A：E＝1:20 | Y＝3.1209+1.4328X | 20.5293 | 144.25 |
| A：E＝1:10 | Y＝3.1150+1.5298X | 17.0694 | 166.98 |
| A：E＝1:1 | Y＝2.9156+2.0473X | 10.4259 | 201.99 |
| A：E＝10:1 | Y＝2.8665+2.0657X | 10.7852 | 154.83 |
| A：E＝20:1 | Y＝2.8345+2.0236X | 11.7529 | 139.02 |
| A：E＝30:1 | Y＝2.7827+2.0041X | 12.7754 | 126.93 |
Toxicity Determination result show, within the scope of weight ratio 1:30-30:1, prothioconazoles and Shen piperazine mycin mixture, its co-toxicity coefficient is all greater than 120, all shows synergistic effect, has obvious synergistic effect, control efficiency excellence and be better than single dose kind.Wherein, prothioconazoles and Shen piperazine mycin weight ratio are within the scope of 1:20 ~ 20:1, especially within the scope of 1:10-10:1, show as more obvious synergistic effect, can reach and effectively prevent and treat wheat powdery mildew, reduce the object of single dose consumption, there is extremely strong Development volue.
For making the technical problem to be solved in the present invention, technical scheme and advantage clearly, within the scope of weight ratio 1:30-30:1, building prothioconazoles and the composite embodiment of Shen piperazine mycin, be described in detail, but the present invention being limited to absolutely not these examples.
Bactericidal composition of the present invention can be prepared into any one formulation of applicable agricultural use by known method, reasonable formulation is wetting powder, aqueous suspension agent, oil-suspending agent, suspended emulsion, water dispersible granules.In all formulas, percentage is all weight percentage.The processing technology of the various formulation of the present composition is prior art, can change to some extent according to different situations.
Below in conjunction with embodiment, content of the present invention is described further.
Embodiment 1:15.5% prothioconazoles Shen piperazine mycin wetting powder (30:1)
Take 15% prothioconazoles, 0.5% Shen piperazine mycin, 4% neopelex, 4% dodecyl sodium naphthalene sulfonate, 3% lignin, 8% white carbon, fine particle calcium carbonate adds to 100% weight portion.
Preparation method: each combined hybrid is even, first through mechanical crushing, then after air-flow crushing, mixes, can obtain 15.5% prothioconazoles Shen piperazine mycin wetting powder.
Embodiment 2:10% prothioconazoles Shen piperazine mycin suspending agent (1:1)
Take 5% prothioconazoles, 5% Shen piperazine mycin, 5% phosphate APEO, 2% isomery octanol APEO, 6% ethylene glycol, 0.32%XG, 0.6% silicone defoaming agent, 0.5% Sodium Benzoate, deionized water adds to 100% weight portion.Preparation method: each component is mixed, mixes through high speed shear, then by sand mill sand milling 2-3 hour, reach fineness 1-5 micron, 10% prothioconazoles Shen piperazine mycin suspending agent can be obtained.
Embodiment 3:11% prothioconazoles Shen piperazine mycin dry suspending agent (10:1)
Take 10% prothioconazoles, 1% Shen piperazine mycin, 3% neopelex, 4% lauryl sodium sulfate, 2% polycarboxylic acids sodium, kaolin complements to 100% weight portion.Preparation method: each component mixed, adds the water of weight equivalents, mixes, reach fineness 1-4 micron, after spraying dry, can obtain 11% prothioconazoles Shen piperazine mycin dry suspending agent through sand mill sand milling by high shear dispersion machine after shearing 30min.
Embodiment 4:21% prothioconazoles Shen piperazine mycin wetting powder (20:1)
Take 20% prothioconazoles, 1% Shen piperazine mycin, 5% dodecyl sodium naphthalene sulfonate, 4% aliphatic alcohol polyethenoxy base ether, 4% sodium lignin sulfonate, 6% white carbon, talcum powder adds to 100% weight portion, preparation method: by even for each combined hybrid, first through mechanical crushing, again after air-flow crushing, mix, 21% prothioconazoles Shen piperazine mycin wetting powder can be obtained.
Embodiment 5:22% prothioconazoles Shen piperazine mycin wetting powder (1:10)
Take 2% prothioconazoles, 20% Shen piperazine mycin, 4% neopelex, 4% dodecyl sodium naphthalene sulfonate, 3% lignin, 8% white carbon, fine particle calcium carbonate adds to 100% weight portion, preparation method: the same, can obtain 22% prothioconazoles Shen piperazine mycin wetting powder.
Embodiment 6:21% prothioconazoles Shen piperazine mycin suspending agent (1:20)
Take 1% prothioconazoles, 20% Shen piperazine mycin, 5% phosphate APEO, 2% isomery octanol APEO, 6% ethylene glycol, 0.32%XG, 0.6% silicone defoaming agent, 0.5% Sodium Benzoate, deionized water adds to 100% weight portion.Preparation method: the same, can obtain 21% prothioconazoles Shen piperazine mycin suspending agent.
Prothioconazoles Shen piperazine mycin water dispersible granules (1:30) of embodiment 7:31%
Take 1% prothioconazoles, 30% Shen piperazine mycin, 5% sodium naphthalene sulfonate, 4% polycarboxylic acids sodium, 2% calcium chloride, talcum powder adds to 100% weight portion, preparation method: mix, each component through mechanical crushing, again through air-flow crushing, mix, then dry through wet granulation, can obtain 31% prothioconazoles Shen piperazine mycin water dispersible granules.
Prothioconazoles jinggangmeisu suspending agent water dispersible granules (1:30) of embodiment 8:31%
Take 1% prothioconazoles, 30% jinggangmeisu, 5% sodium naphthalene sulfonate, 4% polycarboxylic acids sodium, 2% calcium chloride, talcum powder adds to 100% weight portion, preparation method: the same, can obtain 31% prothioconazoles jinggangmeisu water dispersible granules.
Embodiment 9:21% prothioconazoles jinggangmeisu suspending agent (1:20)
Take 1% prothioconazoles, 20% jinggangmeisu, 5% phosphate APEO, 2% isomery octanol APEO, 6% ethylene glycol, 0.32%XG, 0.6% silicone defoaming agent, 0.5% Sodium Benzoate, deionized water adds to 100% weight portion.Preparation method: the same, can obtain 21% prothioconazoles jinggangmeisu suspending agent.
Embodiment 10:10% prothioconazoles jinggangmeisu suspending agent (1:1)
Take 5% prothioconazoles, 5% jinggangmeisu, 5% phosphate APEO, 2% isomery octanol APEO, 6% ethylene glycol, 0.32%XG, 0.6% silicone defoaming agent, 0.5% Sodium Benzoate, deionized water adds to 100% weight portion.Preparation method: the same, can obtain 10% prothioconazoles jinggangmeisu suspending agent.
Embodiment 11:21% prothioconazoles jinggangmeisu wetting powder (20:1)
Take 20% prothioconazoles, 1% jinggangmeisu, 5% dodecyl sodium naphthalene sulfonate, 4% aliphatic alcohol polyethenoxy base ether, 4% sodium lignin sulfonate, 6% white carbon, talcum powder adds to 100% weight portion, preparation method: the same, can obtain 21% prothioconazoles jinggangmeisu wetting powder.
Find through experiment, the prothioconazoles in above embodiment and Shen piperazine mycin adjust arbitrarily within the scope of weight ratio 1:30-30:1, to form new embodiment.No longer carry out this repeating to enumerate, it should be pointed out that for those skilled in the art, under the prerequisite not departing from principle of the present invention, can also make some improvements and modifications, these improvements and modifications also should be considered as protection scope of the present invention.
Inventor finds usually other triazole bactericidal agents and Shen piperazine mycin is composite also certain synergistic effect.Therefore, in the proportion identical with embodiment, construct other triazole bactericidal agents and the composite comparative example of Shen piperazine mycin.By contrast control efficiency; illustrate that the composite control efficiency of the prothioconazoles that the present invention protects and Shen piperazine mycin is better than other triazole bactericidal agents and the composite control efficiency of Shen piperazine mycin (because length is limited, only listing most representational triazole bactericidal agent Tebuconazole, Difenoconazole, epoxiconazole or bitertanol bactericide compounded with various antibiotics respectively in comparative example).Be described in detail.It should be pointed out that the composite control efficiency of prothioconazoles and Shen piperazine mycin is better than other triazole bactericidal agents and the composite control efficiency of Shen piperazine mycin, be not only confined in limited comparative example.
Comparative example 1:10% Tebuconazole Shen piperazine mycin suspending agent (1:1)
Take 5% Tebuconazole, 5% Shen piperazine mycin, 5% phosphate APEO, 2% isomery octanol APEO, 6% ethylene glycol, 0.32%XG, 0.6% silicone defoaming agent, 0.5% Sodium Benzoate, deionized water adds to 100% weight portion.Preparation method: the same, can obtain 10% Tebuconazole Shen piperazine mycin suspending agent.
Comparative example 2:15.5% Tebuconazole Shen piperazine mycin wetting powder (30:1)
Take 15% Tebuconazole, 0.5% Shen piperazine mycin, 4% neopelex, 4% dodecyl sodium naphthalene sulfonate, 3% lignin, 8% white carbon, fine particle calcium carbonate adds to 100% weight portion, preparation method: the same, can obtain 15.5% Tebuconazole Shen piperazine mycin wetting powder.
Comparative example 3:31% Tebuconazole Shen piperazine mycin water dispersible granules (1:30)
Take 1% Tebuconazole, 30% Shen piperazine mycin, 5% sodium naphthalene sulfonate, 4% polycarboxylic acids sodium, 2% calcium chloride, talcum powder adds to 100% weight portion, preparation method: the same, can obtain 31% prothioconazoles Shen piperazine mycin water dispersible granules.
Comparative example 4:10% Difenoconazole Shen piperazine mycin suspending agent (1:1)
Take 5% Difenoconazole, 5% Shen piperazine mycin, 5% phosphate APEO, 2% isomery octanol APEO, 6% ethylene glycol, 0.32%XG, 0.6% silicone defoaming agent, 0.5% Sodium Benzoate, deionized water adds to 100% weight portion.Preparation method: the same, can obtain 10% Difenoconazole Shen piperazine mycin suspending agent.
Comparative example 5:11% Difenoconazole Shen piperazine mycin dry suspending agent (10:1)
Take 10% Difenoconazole, 1% Shen piperazine mycin, 3% neopelex, 4% lauryl sodium sulfate, 2% polycarboxylic acids sodium, kaolin complements to 100% weight portion.Preparation method: each component mixed, adds the water of weight equivalents, mixes, reach fineness 1-4 micron, after spraying dry, can obtain 11% Difenoconazole Shen piperazine mycin dry suspending agent through sand mill sand milling by high shear dispersion machine after shearing 30min.
Comparative example 6:21% Difenoconazole Shen piperazine mycin suspending agent (1:20)
Take 1% Difenoconazole, 20% Shen piperazine mycin, 5% phosphate APEO, 2% isomery octanol APEO, 6% ethylene glycol, 0.32%XG, 0.6% silicone defoaming agent, 0.5% Sodium Benzoate, deionized water adds to 100% weight portion.Preparation method: the same, can obtain 21% Difenoconazole Shen piperazine mycin suspending agent.
Comparative example 7:15.5% nitrile bacterium azoles Shen piperazine mycin wetting powder (30:1)
Take 15% nitrile bacterium azoles, 0.5% Shen piperazine mycin, 4% neopelex, 4% dodecyl sodium naphthalene sulfonate, 3% lignin, 8% white carbon, fine particle calcium carbonate adds to 100% weight portion, preparation method: the same, can obtain 15.5% nitrile bacterium azoles Shen piperazine mycin wetting powder.
Comparative example 8:11% epoxiconazole Shen piperazine mycin dry suspending agent (10:1)
Take 10% epoxiconazole, 1% Shen piperazine mycin, 3% neopelex, 4% lauryl sodium sulfate, 2% polycarboxylic acids sodium, kaolin complements to 100% weight portion.Preparation method: each component mixed, adds the water of weight equivalents, mixes, reach fineness 1-4 micron, after spraying dry, can obtain 11% epoxiconazole Shen piperazine mycin dry suspending agent through sand mill sand milling by high shear dispersion machine after shearing 30min.
Comparative example 9:21% epoxiconazole Shen piperazine mycin suspending agent (1:20)
Take 1% epoxiconazole, 20% Shen piperazine mycin, 5% phosphate APEO, 2% isomery octanol APEO, 6% ethylene glycol, 0.32%XG, 0.6% silicone defoaming agent, 0.5% Sodium Benzoate, deionized water adds to 100% weight portion.Preparation method: the same, can obtain 21% epoxiconazole Shen piperazine mycin suspending agent.
The pesticidal preparations control rice green smut test obtained by above-described embodiment and comparative example.
1, test process: test is carried out with reference to People's Republic of China's standard (pesticide field efficacy medicine test criterion).This test medicine consumption establishes three concentration for the treatment of respectively according to the difference of each composition, and contrast medicament is commercially available agricultural chemicals 25% prothioconazoles SC, 1% Shen piperazine mycin SC, comparative example 1-9 and blank clean water experiment respectively.
2, test method: each plot area is 50m
2, repeat 4 times, the inspection drug effect method before dispenser after Investigation and Prevention is: the diagonal sampling of every community, often clicks 10 strains.Carry out classification with the bacterium ball number on every strain grain, result of the test sees the following form 2:
Table 2 prothioconazoles and the composite control efficiency to rice green smut of Shen piperazine mycin
Field efficacy result shows, obviously, have excellent control efficiency to rice green smut, control efficiency is better than single dose kind for prothioconazoles and Shen piperazine mycin Complex synergism.
When carrying out control efficiency contrast, inventor uses other triazole bactericidal agent composite with Shen piperazine mycin, tests its control efficiency to rice green smut.In identical proportion, find that prothioconazoles and the composite control efficiency of Shen piperazine mycin are better than other triazole bactericidal agents and the composite control efficiency of Shen piperazine mycin.Because length is limited, in comparative example, only list most representational triazole bactericidal agent Tebuconazole, Difenoconazole, epoxiconazole or nitrile bacterium azoles composite with Shen piperazine mycin respectively, to illustrate that prothioconazoles and the composite control efficiency of Shen piperazine mycin are better than other triazole bactericidal agents and the composite control efficiency of Shen piperazine mycin.
Wheat rust test is prevented and treated with the pesticidal preparations that above-described embodiment and comparative example obtain.
1, test process: test is carried out with reference to People's Republic of China's standard (pesticide field efficacy medicine test criterion).This test medicine consumption establishes three concentration for the treatment of respectively according to the difference of each composition, and contrast medicament is commercially available agricultural chemicals 25% prothioconazoles SC and 1% Shen piperazine mycin SC, comparative example 11-19 and blank clean water experiment respectively.
2, test method: each plot area is 50m
2, repeat 4 times, the inspection drug effect method before dispenser after Investigation and Prevention is: the diagonal sampling of every community, often clicks 10 strains.The percentage accounting for whole leaf area with the lesion area on every strain one-piece blade carrys out classification, and result of the test sees the following form 3:
Table 3 prothioconazoles and the composite control efficiency to wheat rust of Shen piperazine mycin
Field efficacy result shows, obviously, have excellent control efficiency to wheat rust, control efficiency is better than single dose kind for prothioconazoles and Shen piperazine mycin Complex synergism.
When carrying out control efficiency contrast, inventor uses other triazole bactericidal agent composite with Shen piperazine mycin, tests its control efficiency to wheat rust.In identical proportion, find that prothioconazoles and the composite control efficiency of Shen piperazine mycin are better than other triazole bactericidal agents and the composite control efficiency of Shen piperazine mycin.Because length is limited, in comparative example, only list most representational triazole bactericidal agent Tebuconazole, Difenoconazole, epoxiconazole or nitrile bacterium azoles composite with Shen piperazine mycin respectively, to illustrate that prothioconazoles and the composite control efficiency of Shen piperazine mycin are better than other triazole bactericidal agents and the composite control efficiency of Shen piperazine mycin, be also better than each single dose kind.
The pesticidal preparations control wheat powdery mildew test obtained by above-described embodiment and comparative example.
1, test process: test is carried out with reference to People's Republic of China's standard (pesticide field efficacy medicine test criterion).This test medicine consumption establishes three concentration for the treatment of respectively according to the difference of each composition, and contrast medicament is commercially available agricultural chemicals 25% prothioconazoles SC, 20% jinggangmycin SP and blank clean water experiment respectively.
2, test method: each plot area is 50m
2, repeat 4 times, the inspection drug effect method before dispenser after Investigation and Prevention is: the diagonal sampling of every community, often clicks 10 strains.The percentage accounting for whole leaf area with the lesion area on every strain one-piece blade carrys out classification, and result of the test sees the following form 4:
Table 4 prothioconazoles and the composite control efficiency to wheat powdery mildew of jinggangmycin
Field efficacy result shows, obviously, all have excellent control efficiency to wheat powdery mildew, control efficiency is better than single dose kind for prothioconazoles and Shen piperazine mycin, prothioconazoles and jinggangmycin Complex synergism.In addition, by effect data table, in identical proportion, find that prothioconazoles and the composite control efficiency of Shen piperazine mycin are better than prothioconazoles and the composite control efficiency of jinggangmycin.
The above is the preferred embodiment of the present invention; it should be pointed out that for those skilled in the art, under the prerequisite not departing from principle of the present invention; can also make some improvements and modifications, these improvements and modifications also should be considered as protection scope of the present invention.
Claims (8)
1. a bactericidal composition, is characterized in that, active ingredient is prothioconazoles and Shen piperazine mycin, and the weight ratio of described prothioconazoles and Shen piperazine mycin is 1:30 ~ 30:1.
2. bactericidal composition according to claim 1, is characterized in that, the weight ratio of described prothioconazoles and Shen piperazine mycin is 1:20 ~ 20:1.
3. bactericidal composition according to claim 2, is characterized in that, the weight ratio of described prothioconazoles and Shen piperazine mycin is 1:10 ~ 10:1.
4. according to described bactericidal composition arbitrary in claims 1 to 3, it is characterized in that, also containing pesticidal preparations auxiliary element in described bactericidal composition, to make the formulation being applicable to agriculturally using.
5. bactericidal composition according to claim 4, is characterized in that, described pesticidal preparations auxiliary element is one or more in solvent, emulsifier, dispersant, stabilizing agent, antifreezing agent or wetting agent.
6. bactericidal composition according to claim 4, is characterized in that, the formulation of described bactericidal composition is suspending agent, dry suspending agent, water dispersible granules or wetting powder.
7. the application of bactericidal composition according to claim 1 in the pesticidal preparations of preparation controlling plant diseases.
8. the application of bactericidal composition according to claim 7, is characterized in that, for the preparation of the pesticidal preparations of the water prevention rice sheath blight, rice blast, false smut, wheat rust or powdery mildew.
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| CN105284337A (en) * | 2015-06-25 | 2016-02-03 | 吉林省吉阳农业科学研究院 | Organic cultivation method of northern paddy rice |
| CN105707083B (en) * | 2016-01-20 | 2017-11-14 | 南京农业大学 | A kind of purposes of effects enhancing and dose reducing composition pesticide in gibberella zeaze petch of wheat and barley is prevented and treated |
| CN106719784A (en) * | 2016-12-07 | 2017-05-31 | 河南农业大学 | Microbicide compositions and its application for preventing and treating wheat root disease |
| CN106718406A (en) * | 2017-01-11 | 2017-05-31 | 贵州省植物园 | A kind of method for preventing and treating Rose Powdery Mildew |
| CN106889077B (en) * | 2017-05-04 | 2018-08-17 | 佛山市瑞生通科技有限公司 | Bactericidal composition containing pheno second mycin and prothioconazoles and its application |
| CN110050793A (en) * | 2019-05-22 | 2019-07-26 | 安徽久易农业股份有限公司 | Prothioconazoles dry suspending agent, preparation method and application |
| CN113287622A (en) * | 2021-05-25 | 2021-08-24 | 贵州道元生物技术有限公司 | Compound bactericide for preventing and treating cucumber bacterial angular leaf spot |
| CN117481123B (en) * | 2023-12-29 | 2024-03-08 | 黑龙江省农业科学院水稻研究所 | Agricultural bactericidal composition |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005067716A1 (en) * | 2004-01-20 | 2005-07-28 | Basf Aktiengesellschaft | Fungicidal mixtures |
| CN103155926A (en) * | 2011-12-18 | 2013-06-19 | 深圳诺普信农化股份有限公司 | Sterilization composite based on phenazino-1-carboxylicacid |
| CN104026136A (en) * | 2014-06-16 | 2014-09-10 | 深圳诺普信农化股份有限公司 | Agricultural fungicidal composition |
-
2014
- 2014-09-30 CN CN201410522406.6A patent/CN104222138A/en active Pending
-
2015
- 2015-09-07 CN CN201510564623.6A patent/CN105191946B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005067716A1 (en) * | 2004-01-20 | 2005-07-28 | Basf Aktiengesellschaft | Fungicidal mixtures |
| CN103155926A (en) * | 2011-12-18 | 2013-06-19 | 深圳诺普信农化股份有限公司 | Sterilization composite based on phenazino-1-carboxylicacid |
| CN104026136A (en) * | 2014-06-16 | 2014-09-10 | 深圳诺普信农化股份有限公司 | Agricultural fungicidal composition |
Non-Patent Citations (2)
| Title |
|---|
| 关爱莹 等: "新型三唑硫酮类杀菌剂丙硫菌唑", 《农药》 * |
| 张爱萍 等: "新型三唑硫酮类杀菌剂丙硫菌唑的研究进展", 《今日农药》 * |
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