CN106798851A - 一种用于治疗肾阴虚的内服药物及其制备方法 - Google Patents

一种用于治疗肾阴虚的内服药物及其制备方法 Download PDF

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CN106798851A
CN106798851A CN201710087726.7A CN201710087726A CN106798851A CN 106798851 A CN106798851 A CN 106798851A CN 201710087726 A CN201710087726 A CN 201710087726A CN 106798851 A CN106798851 A CN 106798851A
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夏瑜
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Chengdu Feilong Water Treatment Technology Research Institute Qingbaijiang First Branch
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Abstract

本发明属于中药制剂领域,目的是根据中医对肾阴虚的认识机理而提供的一种用于治疗肾阴虚的内服药物,所述药物的各个组分及其质量份比如下:桑螵蛸8g、酒黄精20g、熟地黄30g、枸杞子20g、山茱萸(去核)12g、五味子10g、菟丝子23g、覆盆子12g、牡丹皮12g、茯苓12g、炒芡实28g、桃仁12g、鹿角胶6g、制首乌17g、远志10g、党参20g、龟板胶20g、金樱子12g、山药(炒)28g、当归14g、麦冬(去心)12g、石斛12g、白茅根28g;本发明提供的药物是一个标本兼治的中药组方。

Description

一种用于治疗肾阴虚的内服药物及其制备方法
技术领域
本发明属于中药制剂领域,具体涉及一种用于治疗肾阴虚的内服药物,特别是供肾阴虚患者使用的内服药物及其制备方法的领域。
背景技术
肾阴虚,肾虚的一种类型,为中医名词术语。是指由于肾阴亏损,失于滋养,虚热内生所表现的证候,中医临床称为肾阴虚证。多由久病耗伤,或禀赋不足,或房劳过度,或过服温燥劫阴之品所致。证见腰膝酸痛,头晕耳鸣,失眠多梦,五心烦热,潮热盗汗,遗精早泄,咽干颧红,舌红少津无苔,脉细数等。治宜滋阴降火。
那么,就如何找到一种可有效治疗上述肾阴虚的药物,是本领域技术人员亟待要解决的课题。
发明内容
随着我国中医中药学的不断发展,在治疗肾阴虚上,人们逐渐意识到了中医治疗肾阴虚的优点,且在治疗过程中疗效好、见效快、毒副作用小等优势,针对现有西医治疗肾阴虚的现状,本发明的目的是在于提供一种用于治疗肾阴虚的内服药物,以解决肾阴虚患者早日恢复健康的问题。该药物是以常见的中药为原料,通过选择合理的药物
及质量份比,可有效治疗上述肾阴虚一证。
为达到上述发明的目的,本发明所采用的技术方案为:提供一种用于治疗肾阴虚的内服药物及其制备方法,其特征在于,所述药物的各个组分及其质量份比如下所示:
桑螵蛸5~10g、酒黄精15~26g、熟地黄10~38g、枸杞子10~25g、山茱萸(去核)6~15g、五味子3~12g、菟丝子15~30g、覆盆子8~15g、牡丹皮8~16g、茯苓10~16g、炒芡实15~35g、桃仁8~16g、鹿角胶3~8g、制首乌10~22g、远志3~12g、党参15~25g、龟板胶5~25g、金樱子8~16g、山药(炒)15~35g、当归8~18g、麦冬(去心)6~16g、石斛6~16g、白茅根10~35g。
一种用于治疗肾阴虚的内服药物及其制备方法,其特征在于,所述药物的各个组分及其质量份比如下所示:
桑螵蛸6~9g、酒黄精18~23g、熟地黄12~33g、枸杞子11~22g、山茱萸(去核)8~13g、五味子6~11g、菟丝子18~26g、覆盆子10~13g、牡丹皮10~14g、茯苓11~14g、炒芡实17~31g、桃仁10~14g、鹿角胶5~7g、制首乌11~20g、远志5~11g、党参18~22g、龟板胶8~22g、金樱子10~14g、山药(炒)17~31g、当归10~16g、麦冬(去心)8~14g、石斛8~14g、白茅根11~31g。
一种用于治疗肾阴虚的内服药物及其制备方法,其特征在于,所述“最佳方案”的药物的各个组分及其质量份比如下所示:
桑螵蛸8g、酒黄精20g、熟地黄30g、枸杞子20g、山茱萸(去核)12g、五味子10g、菟丝子23g、覆盆子12g、牡丹皮12g、茯苓12g、炒芡实28g、桃仁12g、鹿角胶6g、制首乌17g、远志10g、党参20g、龟板胶20g、金樱子12g、山药(炒)28g、当归14g、麦冬(去心)12g、石斛12g、白茅根28g。
一种用于治疗肾阴虚的内服药物及其制备方法,其特征在于,所述方法包括如下步骤制备而成:
A、除鹿角胶、龟板胶(烊化兑服)外,将上述原料中药拣去杂质和粉尘后,按照质量份比分别粉碎成粗粒状包煎;
B、将包好的原料中药放入冷开水中浸泡30min,然后再将浸泡好的药物和浸泡药物的澄清液一并放入砂锅内,注入过药66mm的冷开水进行第一次煎煮50min,滤取药液后,再次注入过药62mm的微温开水进行第二次煎煮40min,二次混合浓缩成50%的中药液540毫升备用。
一种用于治疗肾阴虚的内服药物及其制备方法,其特征在于,所述服用方法为:将制备好的中药液以一天服用,早中晚各服一次,给药量180ml/次,饭后温服。15天为一个疗程,服药2~4个疗程,症状消失,病获痊愈。
本发明组方中的各原料中药在中国药典、中国辞典以及中华本草中均有详细的记载。本发明选用其中最常见的中药为原料,充分发挥各组分的药理功效:
桑螵蛸,性味:甘、咸、平,具有益肾固精、缩尿、止浊之功效,用于治疗遗精滑精、遗尿尿频、小便白浊;
酒黄精,性味:甘、平,具有养阴润肺、补脾益气、滋肾填精之功效,用于治疗阴虚劳嗽、肺燥咳嗽、脾虚乏力、食少口干、消渴、肾亏腰膝酸软、阳痿遗精、耳鸣目暗、须发早白、体虚赢瘦、风癞癣疾等症;
熟地黄,性味:味甘、性温,具有补血滋润、益精填髓之功效,用于治疗血虎萎黄、眩晕心悸、月经不调、崩不止、肝肾阴亏、潮热盗汗、遗精阳痿、不育不孕、腰膝酸软、耳鸣耳聋、头目昏花、须发早白、消渴、便秘、肾虚喘促;
枸杞子,性味:味甘、性平,具有养肝、滋肾、润肺之功效,用于治疗肝肾亏虚、头晕目眩、目视一清、腰膝酸软、阳痿贵精、虚劳咳嗽、消渴引饮;
山茱萸(去核),性味:酸、涩、微温,具有补益肝肾、涩精固脱之功效,用于治疗眩晕耳鸣、腰膝酸痛、阳痿遗精、遗尿尿频、崩漏带下、大汗虚脱、内热消渴,此外,本品又能固经止血,可用治妇女体虚、月经过多等症;
五味子,性味:酸、甘、温,具有收敛固涩、益气生津、补肾宁心之功效,用于治疗久泻不止、久咳虚喘、心悸、失眠、多梦、自汗、盗汗、津伤口渴、消渴、遗精、滑精;
菟丝子,性味:辛甘、平,具有补肾益精、养肝明目、固胎止泄之功效,用于治疗腰膝酸痛、遗精、阳痿、早泄、不育、消渴、淋浊、遗尿、目昏耳鸣、胎动不安、流产、泄泻等症;
覆盆子,性味:甘酸、平,无毒,具有补肝益肾、固精缩尿、明目之功效,用于治疗阳痿早泄、遗精滑精、宫冷不孕、带下清稀、尿频遗溺、目昏暗、须发早白;
牡丹皮,性味:辛苦、凉,具有清热、凉血、和血、消瘀之功效,用于治疗热入血分、发斑、惊痫、吐、衄、便血、骨蒸劳热、经闭、症瘕、痈疡、扑损等症;
茯苓,性味:甘、淡、平,具有利水药、渗湿利尿药之功效,用于治疗小便不利、水肿胀满、痰饮咳逆、呕吐、脾虚食少、泄泻、心悸不安、失眠健忘、遗精白浊;
炒芡实,性味:甘、涩、平,具有益肾固精、补脾止泻、祛湿止带之功效,用于治疗梦遗滑精、遗尿尿频、脾虚久泻、白浊、带下等病症;
桃仁,性味:苦甘、平,无毒,具有破血行瘀、润燥滑肠之功效,用于治疗经闭、癥瘕、热病蓄血、风痹、疟疾、跌打损伤、瘀血肿痛、血燥便秘;
鹿角胶,性味:甘、咸、温,具有温补肝肾、益精养血之功效,用于治疗阳痿滑精、腰膝酸冷、虚劳羸瘦、崩漏下血、便血尿血、阴疽肿痛;
制首乌,性味:苦、甘、涩、性微温,具有养血滋阴、润肠通便、截疟、祛风、解毒之功效,用于治疗血虚头昏目眩、心悸、失眠、肝肾阴虚之腰膝酸软、须发早白、耳鸣、遗精、肠燥便秘、久疟体虚、风疹瘙痒、疮痈、瘰疬、痔疮等症;
远志,性味:苦、辛、微温,具有安神益智、祛痰、消肿之功效,用于治疗心肾不交引起的失眠多梦、健忘惊悸、神志恍惚、咳痰不爽、疮疡肿毒、乳房肿痛;
党参,性味:味甘、性平,具有健脾补肺、益气生津之功效,用于治疗脾胃虚弱、食少便溏、四肢乏力、肺虚喘咳、气短自汗、气微两亏等症;
龟板胶,性味:甘咸、平,具有滋阴、补血、止血之功效,用于治疗阴虚血亏、劳热骨蒸、吐血、衄血、烦热惊悸、肾虚腰痛、脚膝痿弱、崩漏、带下等症;
金樱子,性味:酸涩、平、无毒,具有固精、缩尿、涩肠、止带之功效,用于治疗滑精、遗尿、尿频、久泻、久痢、白浊、白带、崩漏、脱肛、子宫下垂;
山药(炒),性味:甘、平,具有健脾、补肺、固肾、益精之功效,用于治疗脾虚泄泻、久痢、虚劳咳嗽、消渴、遗精、带下、小便频数;另具补脾养胃、生津益肺、补肾涩精之功效,用于脾虚食少、久泻不止、肺虚喘咳、肾虚遗精、带下、尿频、虚热消渴;
当归,性味:性温、味甘辛,具有补血和血、调经止痛、润燥滑肠之功效,用于治疗血虚、面色萎黄、眩晕心悸、血虚、或兼有瘀滞的月经不调、经闭、痛经、虚寒性腹痛、冠心病心绞痛、风湿痹痛、跌打损伤;
麦冬(去心),性味:甘、微苦微寒,具有养阴润肺、益胃清心之功效,用于治疗阴虚肺燥、干咳痰稠、劳嗽咯血、津少口渴、心烦失眠、肠燥便秘;
石斛,性味:甘、微寒, 具有生津益胃、滋阴清热、润肺益肾、明目强腰之功效,用于治疗热病伤津、口干烦渴、胃阴不足、胃痛干呕、肺燥干咳、虚热不退、阴伤目暗、腰膝软弱;
白茅根,性味:甘、寒, 具有凉血止血、清热生津、利尿通淋之功效,用于治疗血热出血、热病烦渴、胃热呕逆、肺热喘咳、小便淋沥涩痛、水肿、黄疸等症。
本发明药物是基于中医治疗肾阴虚的原则,从依据肾阴虚的病理机制及药理作用认为:就肾阳虚,本发明所提供的药物中的各原料中药药效共奏,对上述疾病有很好的治疗效果。
具体实施方式
本发明就是针对上述肾阴虚的治疗而提出的一种中药配方,采用该配方制备的药物药效好,见效快,是一个标本兼治的中药组方,特别适合临床使用。下面结合本发明的具体实施方式作进一步详细的描述:
实施例1:
一种用于治疗肾阴虚的内服药物,其特征在于,所述药物的各个组分及其质量份比如下所示:
桑螵蛸8g、酒黄精20g、熟地黄30g、枸杞子20g、山茱萸(去核)12g、五味子10g、菟丝子23g、覆盆子12g、牡丹皮12g、茯苓12g、炒芡实28g、桃仁12g、鹿角胶6g、制首乌17g、远志10g、党参20g、龟板胶20g、金樱子12g、山药(炒)28g、当归14g、麦冬(去心)12g、石斛12g、白茅根28g。
实施例2:
一种用于治疗肾阴虚的内服药物,其特征在于,所述药物的各个组分及其质量份比如下所示:
桑螵蛸9g、酒黄精23g、熟地黄33g、枸杞子22g、山茱萸(去核)13g、五味子11g、菟丝子26g、覆盆子13g、牡丹皮14g、茯苓14g、炒芡实31g、桃仁14g、鹿角胶7g、制首乌20g、远志11g、党参22g、龟板胶22g、金樱子14g、山药(炒)31g、当归16g、麦冬(去心)14g、石斛14g、白茅根31g。
实施例3:
一种用于治疗肾阴虚的内服药物,其特征在于,所述药物的各个组分及其质量份比如下所示:
桑螵蛸10g、酒黄精26g、熟地黄38g、枸杞子25g、山茱萸(去核)15g、五味子12g、菟丝子30g、覆盆子15g、牡丹皮16g、茯苓16g、炒芡实35g、桃仁16g、鹿角胶8g、制首乌22g、远志12g、党参25g、龟板胶25g、金樱子16g、山药(炒)35g、当归18g、麦冬(去心)16g、石斛16g、白茅根35g。
典型病例
经临床诊断治疗肾阴虚患者共770例,年龄为48岁以上的450例,只有320例为48岁以下。770例患者中痊愈的600例,有效的170例,总有效率达100%。

Claims (3)

1.一种用于治疗肾阴虚的内服药物,其特征在于,所述药物的各个组分及其质量份比如下所示:
桑螵蛸5~10g、酒黄精15~26g、熟地黄10~38g、枸杞子10~25g、山茱萸(去核)6~15g、五味子3~12g、菟丝子15~30g、覆盆子8~15g、牡丹皮8~16g、茯苓10~16g、炒芡实15~35g、桃仁8~16g、鹿角胶3~8g、制首乌10~22g、远志3~12g、党参15~25g、龟板胶5~25g、金樱子8~16g、山药(炒)15~35g、当归8~18g、麦冬(去心)6~16g、石斛6~16g、白茅根10~35g。
2.根据权利要求1所述的用于治疗肾阴虚的内服药物,其特征在于,所述药物的各个组分及其质量份比如下所示:
桑螵蛸6~9g、酒黄精18~23g、熟地黄12~33g、枸杞子11~22g、山茱萸(去核)8~13g、五味子6~11g、菟丝子18~26g、覆盆子10~13g、牡丹皮10~14g、茯苓11~14g、炒芡实17~31g、桃仁10~14g、鹿角胶5~7g、制首乌11~20g、远志5~11g、党参18~22g、龟板胶8~22g、金樱子10~14g、山药(炒)17~31g、当归10~16g、麦冬(去心)8~14g、石斛8~14g、白茅根11~31g。
3.根据权利要求1至2所述的用于治疗肾阴虚的内服药物,其特征在于,所述药物的各个组分及其质量份比如下所示:
桑螵蛸8g、酒黄精20g、熟地黄30g、枸杞子20g、山茱萸(去核)12g、五味子10g、菟丝子23g、覆盆子12g、牡丹皮12g、茯苓12g、炒芡实28g、桃仁12g、鹿角胶6g、制首乌17g、远志10g、党参20g、龟板胶20g、金樱子12g、山药(炒)28g、当归14g、麦冬(去心)12g、石斛12g、白茅根28g。
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