CN106853186A - 一种治疗肾阴虚的中药组合物及其制备方法 - Google Patents
一种治疗肾阴虚的中药组合物及其制备方法 Download PDFInfo
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- CN106853186A CN106853186A CN201710081808.0A CN201710081808A CN106853186A CN 106853186 A CN106853186 A CN 106853186A CN 201710081808 A CN201710081808 A CN 201710081808A CN 106853186 A CN106853186 A CN 106853186A
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Abstract
本发明属于中药制剂领域,目的是根据中医对肾阴虚的认识机理而提供的一种治疗肾阴虚的中药组合物,所述中药组合物的各个组分及其质量份比如下:桑螵蛸50~100g、酒黄精150~260g、熟地黄150~450g、枸杞子100~220g、生地黄150~350g、五味子30~120g、泽泻60~120g、菟丝子(盐炒)100~150g、牡丹皮80~160g、覆盆子50~120g、茯苓150~260g、炒芡实150~350g、桃仁80~160g、制何首乌60~120g、远志30~100g、党参150~260g、金樱子90~160g、山药150~350g、女贞子60~160g、当归80~160g、黄柏80~160g、白茅根100~320g、石斛60~150g;本发明提供的药物是一个标本兼治的中药组方。
Description
技术领域
本发明属于中药制剂领域,具体涉及一种治疗肾阴虚的中药组合物,特别是供肾阴虚患者使用的中药组合物及其制备方法的领域。
背景技术
肾阴虚,肾虚的一种类型,为中医名词术语。是指由于肾阴亏损,失于滋养,虚热内生所表现的证候,中医临床称为肾阴虚证。多由久病耗伤,或禀赋不足,或房劳过度,或过服温燥劫阴之品所致。证见腰膝酸痛,头晕耳鸣,失眠多梦,五心烦热,潮热盗汗,遗精早泄,咽干颧红,舌红少津无苔,脉细数等。
那么,就如何找到一种可有效治疗肾阴虚的中药组合物,是我们目前急需要解决的问题。
发明内容
随着我国中医中药学的不断发展,在治疗肾阴虚上,人们逐渐意识到了中医治疗肾阴虚的优点,且在治疗过程中疗效好、见效快、毒副作用小等优势,针对现有西医治疗肾阴虚的现状,本发明的目的是在于提供一种治疗肾阴虚的中药组合物,以解决肾阴虚患者早日恢复健康的问题。该药物是以常见的中药为原料,通过选择合理的药物及质量份比,可有效治疗上述肾阴虚。
为达到上述发明的目的,本发明所采用的技术方案为:提供一种治疗肾阴虚的中药组合物及其制备方法,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:
桑螵蛸50~100g、酒黄精150~260g、熟地黄150~450g、枸杞子100~220g、生地黄150~350g、五味子30~120g、泽泻60~120g、菟丝子(盐炒)100~150g、牡丹皮80~160g、覆盆子50~120g、茯苓150~260g、炒芡实150~350g、桃仁80~160g、制何首乌60~120g、远志30~100g、党参150~260g、金樱子90~160g、山药150~350g、女贞子60~160g、当归80~160g、黄柏80~160g、白茅根100~320g、石斛60~150g。
一种治疗肾阴虚的中药组合物及其制备方法,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:
桑螵蛸60~90g、酒黄精170~230g、熟地黄170~400g、枸杞子115~200g、生地黄170~300g、五味子35~105g、泽泻70~100g、菟丝子(盐炒)115~130g、牡丹皮90~140g、覆盆子60~105g、茯苓170~230g、炒芡实170~300g、桃仁90~140g、制何首乌70~105g、远志35~90g、党参170~230g、金樱子100~140g、山药170~300g、女贞子70~140g、当归90~140g、黄柏90~140g、白茅根115~280g、石斛70~120g。
一种治疗肾阴虚的中药组合物及其制备方法,其特征在于,所述“最佳方案”的中药组合物的各个组分及其质量份比如下所示:
桑螵蛸80g、酒黄精200g、熟地黄350g、枸杞子170g、生地黄260g、五味子90g、泽泻90g、菟丝子(盐炒)110g、牡丹皮120g、覆盆子90g、茯苓200g、炒芡实260g、桃仁120g、制何首乌95g、远志80g、党参200g、金樱子120g、山药260g、女贞子120g、当归120g、黄柏120g、白茅根250g、石斛100g。
一种治疗肾阴虚的中药组合物及其制备方法,其特征在于,所述方法包括如下步骤制备而成:
A、将上述原料中药拣去杂质、粉尘及干燥后,按照质量份比共研为极细末待用;
B、按照传统制备中药胶囊剂的方法,将研磨好的极细末药物过筛后,放入药器中混合均匀,然后制备成胶囊剂(其胶囊锁合后的总长度为23.3mm,药粉容量0.4~0.5g/粒),分装密封即可。
一种治疗肾阴虚的中药组合物及其制备方法,其特征在于,所述服用方法为:将制备好的胶囊剂药物以每日三次服用,早中晚各服一次,给药量2.5g /次,温开水送服。15 天为一个疗程,服药1~2个疗程后,病获痊愈。
本发明组方中的各原料中药在中国药典、中国辞典以及中华本草中均有详细的记载。本发明选用其中最常见的中药为原料,充分发挥各组分的药理功效:
桑螵蛸,性味:甘、咸、平,具有益肾固精、缩尿、止浊之功效,用于治疗遗精滑精、遗尿尿频、小便白浊;
酒黄精,性味:甘、平,具有养阴润肺、补脾益气、滋肾填精之功效,具有阴虚劳嗽、肺燥咳嗽、脾虚乏力、食少口干、消渴、肾亏腰膝酸软、阳痿遗精、耳鸣目暗、须发早白、体虚赢瘦、风癞癣疾;
熟地黄,性味:甘、微温,具有滋阴补血、益精填髓之功效,用于治疗肝肾阴虚、腰膝酸软、骨蒸潮热、盗汗遗精、内热消渴、血虚萎黄、心悸怔忡、月经不调、崩漏下血、眩晕、耳鸣、须发早白;
枸杞子,性味:味甘、性平,具有养肝、滋肾、润肺之功效,用于治疗肝肾亏虚、头晕目眩、目视一清、腰膝酸软、阳痿贵精、虚劳咳嗽、消渴引饮等症;
生地黄,性味:味甘、苦、性寒,具有清热、凉血之功效,用于治疗温热病热入营血、壮热神昏、口干舌绛;
五味子,性味:酸、温,具有敛肺、滋肾、生津、收汗、涩精之功效,用于治疗肺虚喘咳、口干作渴、自汗、盗汗、劳伤羸瘦、梦遗滑精、久泻久痢等症;
泽泻,性味:甘、寒,具有利小便、清湿热之功效,用于治疗小便不利、水肿胀满、泄泻尿少、痰饮眩晕、热淋涩痛,高血脂;
菟丝子(盐炒),性味:温、甘,具有滋补肝肾,安胎,明目,止泻之功效,用于治疗阳痿遗精、尿有余沥、遗尿尿频、药膝酸软、目昏耳鸣、肾虚胎漏、胎动不安、脾肾虚泻,外治白癜风;
牡丹皮,性味:辛苦、凉,具有清热、凉血、和血、消瘀之功效,用于治疗热入血分、发斑、惊痫、吐、衄、便血、骨蒸劳热、经闭、症瘕、痈疡、扑损等症;
覆盆子,性味:甘酸、平,无毒,具有补肝益肾、固精缩尿、明目之功效,用于治疗阳痿早泄、遗精滑精、宫冷不孕、带下清稀、尿频遗溺、目昏暗、须发早白;
茯苓,性味:甘、淡、平,具有渗湿利水、健脾和胃、宁心安神之功效,用于治疗小便不利、水肿胀满、痰饮咳逆、呕吐、脾虚食少、泄泻、心悸不安、失眠健忘、遗精白浊;
炒芡实,性味:甘、涩、平,具有益肾固精、补脾止泻、祛湿止带之功效,用于治疗梦遗滑精、遗尿尿频、脾虚久泻、白浊、带下等病症;
桃仁,性味:苦甘、平,无毒,具有破血行瘀、润燥滑肠之功效,用于治疗经闭、症瘕、热病蓄血、风痹、疟疾、跌打损伤、瘀血肿痛、血燥便秘;
制何首乌,性味:苦、甘、涩、温,具有补肝肾、益精血、乌须发、强筋骨之功效,用于治疗血虚萎黄、眩晕耳鸣、须发早白、腰膝酸软、肢体麻木、崩漏带下、久疟体虚、高血脂;
远志,性味:苦、辛、微温,具有安神益智、祛痰、消肿之功效,用于治疗心肾不交引起的失眠多梦、健忘惊悸、神志恍惚、咳痰不爽、疮疡肿毒、乳房肿痛;
党参,性味:味甘、性平,具有健脾补肺、益气生津之功效,用于治疗脾胃虚弱、食少便溏、四肢乏力、肺虚喘咳、气短自汗、气微两亏等症;
金樱子,性味:酸涩、平,无毒,具有固精,缩尿,涩肠,止带之功效,用于治疗滑精、滑精、遗尿、尿频、久泻、久痢、白浊、白带、崩漏、脱肛、子宫下垂;
山药,性味:甘、平,具有补脾、养肺、固肾、益精之功效,用于治疗脾虚泄泻、食少浮肿、肺虚咳喘、消渴、遗精、带下、肾虚尿频,外用治痈肿、瘰疬等症;
女贞子,性味:甘、苦、凉,具有补益肝肾、明目、清虚热之功效,用于治疗头晕目眩、须发早白、视物昏花、阴虚发热;
当归,性味:性温、味甘辛, 具有补血和血、调经止痛、润燥滑肠之功效,用于治疗血虚、面色萎黄、眩晕心悸、血虚、或兼有瘀滞的月经不调、经闭、痛经、虚寒性腹痛、冠心病心绞痛、风湿痹痛、跌打损伤;
黄柏,性味:苦、寒,具有清热燥湿、泻火解毒、除骨蒸清虚热之功效,用于治疗湿热泻痢、黄疸、带下、热淋、脚气、痿辟、骨蒸劳热、盗汗、遗精、疮疡肿毒、湿疹瘙痒等症;
白茅根,性味:甘、寒, 具有凉血止血、清热生津、利尿通淋之功效,用于治疗血热出血、热病烦渴、胃热呕逆、肺热喘咳、小便淋沥涩痛、水肿、黄疸等症;
石斛,性味:甘、微寒, 具有生津益胃、滋阴清热、润肺益肾、明目强腰之功效,用于治疗热病伤津、口干烦渴、胃阴不足、胃痛干呕、肺燥干咳、虚热不退、阴伤目暗、腰膝软弱。
本发明药物是基于中医治疗肾阴虚的原则,从药理作用及作用机制认为:就肾阴虚,本发明所提供的药物中的各原料中药药效共奏,对上述疾病有很好的治疗效果。
具体实施方式
本发明就是针对上述肾阴虚的治疗而提出的一种中药配方,采用该配方制备的药物药效好,见效快,是一个标本兼治的中药组方,特别适合临床使用。下面结合本发明的具体实施方式作进一步详细的描述:
实施例1:
一种治疗肾阴虚的中药组合物,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:
桑螵蛸80g、酒黄精200g、熟地黄350g、枸杞子170g、生地黄260g、五味子90g、泽泻90g、菟丝子(盐炒)110g、牡丹皮120g、覆盆子90g、茯苓200g、炒芡实260g、桃仁120g、制何首乌95g、远志80g、党参200g、金樱子120g、山药260g、女贞子120g、当归120g、黄柏120g、白茅根250g、石斛100g。
实施例2:
一种治疗肾阴虚的中药组合物,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:
桑螵蛸90g、酒黄精230g、熟地黄400g、枸杞子200g、生地黄300g、五味子105g、泽泻100g、菟丝子(盐炒)130g、牡丹皮140g、覆盆子105g、茯苓230g、炒芡实300g、桃仁140g、制何首乌105g、远志90g、党参230g、金樱子140g、山药300g、女贞子140g、当归140g、黄柏140g、白茅根280g、石斛120g。
实施例3:
一种治疗肾阴虚的中药组合物,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:
桑螵蛸100g、酒黄精260g、熟地黄450g、枸杞子220g、生地黄350g、五味子120g、泽泻120g、菟丝子(盐炒)150g、牡丹皮160g、覆盆子120g、茯苓260g、炒芡实350g、桃仁160g、制何首乌120g、远志100g、党参260g、金樱子160g、山药350g、女贞子160g、当归160g、黄柏160g、白茅根320g、石斛150g。
典型病例
经临床诊断治疗肾阴虚患者共1015例,年龄为49岁以上的510例,只有505例为49岁以下。1015例患者中痊俞的925例,显效的的90例,总有效率达100%。
Claims (3)
1.一种治疗肾阴虚的中药组合物,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:
桑螵蛸50~100g、酒黄精150~260g、熟地黄150~450g、枸杞子100~220g、生地黄150~350g、五味子30~120g、泽泻60~120g、菟丝子(盐炒)100~150g、牡丹皮80~160g、覆盆子50~120g、茯苓150~260g、炒芡实150~350g、桃仁80~160g、制何首乌60~120g、远志30~100g、党参150~260g、金樱子90~160g、山药150~350g、女贞子60~160g、当归80~160g、黄柏80~160g、白茅根100~320g、石斛60~150g。
2.根据权利要求1所述的治疗肾阴虚的中药组合物,其特征在于,所述药物的各个组分及其质量份比如下所示:
桑螵蛸60~90g、酒黄精170~230g、熟地黄170~400g、枸杞子115~200g、生地黄170~300g、五味子35~105g、泽泻70~100g、菟丝子(盐炒)115~130g、牡丹皮90~140g、覆盆子60~105g、茯苓170~230g、炒芡实170~300g、桃仁90~140g、制何首乌70~105g、远志35~90g、党参170~230g、金樱子100~140g、山药170~300g、女贞子70~140g、当归90~140g、黄柏90~140g、白茅根115~280g、石斛70~120g。
3.根据权利要求1至2所述的治疗肾阴虚的中药组合物,其特征在于,所述药物的各个组分及其质量份比如下所示:
桑螵蛸80g、酒黄精200g、熟地黄350g、枸杞子170g、生地黄260g、五味子90g、泽泻90g、菟丝子(盐炒)110g、牡丹皮120g、覆盆子90g、茯苓200g、炒芡实260g、桃仁120g、制何首乌95g、远志80g、党参200g、金樱子120g、山药260g、女贞子120g、当归120g、黄柏120g、白茅根250g、石斛100g。
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