CN106728001A - It is a kind of to promote composition of eyelashes growth and preparation method thereof - Google Patents
It is a kind of to promote composition of eyelashes growth and preparation method thereof Download PDFInfo
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- CN106728001A CN106728001A CN201611164280.5A CN201611164280A CN106728001A CN 106728001 A CN106728001 A CN 106728001A CN 201611164280 A CN201611164280 A CN 201611164280A CN 106728001 A CN106728001 A CN 106728001A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/66—Papaveraceae (Poppy family), e.g. bloodroot
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/55—Glands not provided for in groups A61K35/22 - A61K35/545, e.g. thyroids, parathyroids or pineal glands
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/288—Taraxacum (dandelion)
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/981—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of mammals or bird
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth
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Abstract
Promote composition of eyelashes growth and preparation method thereof the present invention relates to a kind of.Said composition is prepared from by following raw material:Meadowrueleaf corydalis root, Moschus, dandelion.Present invention also offers the preparation method of this composition.The composition that the present invention is provided can promote absorption of the Eyelash follicle to nutritional ingredient, accelerate eyelashes fast breeding, increase eyelashes quantity, and can prevent the growth of fat granule.
Description
Technical field
The present invention relates to the field of Chinese medicines, and in particular to a kind of composition of promotion eyelashes growth and preparation method thereof.
Background technology
Eyelashes long, it is in high spirit, the sensation that a kind of eyes can discharge can be given people, everyone wants to possess beautiful eyelash
Hair, because beautiful eyelashes can allow eyes more beautiful, eyelash is the hair nearest from eyes, while being also most tender and lovely hair
Hair.Life-span of the eyelashes in hair is most short, and average life span only has 3-5 month.Hair with other positions of human body is the same, eyelashes
Will by growth period, rest period, the phase of coming off do not stop circulation.The growth period of eyelashes is extremely short, only about 1 month, and stops
The dormancy phase but came off about 3-5 days phase up to 3-5 months, and our eyelashes have more than 90% in a dormant state, this with hair 90% at
In growth period, and for a long time up to 2-6 formation sharp contrasts, here it is why hair is growed quickly, and eyelashes how
The reason for long.
Eyelashes are one of human body organs the most fragile, and its cacesthesia not only to foreign matter is sensitive, and itself also can be with
The passage of time and increasingly aging brittle failure.And the length of eyelashes varies with each individual with dense, generally, European crimping eyelash angle
Greatly, be relatively large in diameter, it is relatively dense;And Asian is then in contrast.In addition, the people's eyelashes more than Eyelash follicle are more dense,
The strong people's eyelashes of hair follicle growth ability are then longer.For individuality, the upper eyelid eyelashes of people are grown more, generally there is 100-150 roots, long
8-12 millimeters of average out to of degree;Lower eyelid eyelashes are short and lack, about 50-75 roots, and length is about 6-8 millimeters.Malnutritive or long-term illness
Deng can cause deplumation.
The agitation of grafting eyelashes is attacked, this also let us gradually eyelashes are paid attention to.But having to, it is genuine to connect eyelashes
It is expensive and time-consuming, also injures very much itself eyelashes.Therefore, eyelashes natural increase how is allowed increasingly to cause the note of people seeking beauty
Meaning.
Chinese patent literature CN103860417A discloses a kind of eyelashes growth-promoting media, and it is mainly by centella elite, daisy
Elite, olive oil, the tuber of pinellia, ginger, vitamin E etc. are mixed according to certain ratio.Chinese patent literature
CN104666135A discloses a kind of natural eyelashes growth-promoting media, and its component is:Olive oil, vitamin E, ginger juice, Rosa Damascana.
Chinese patent literature CN105232358A discloses a kind of compound for promoting eyelashes to grow, composition:Myristoyl pentapeptide -17,
Myristoyl hexapeptide -16, biotin tripeptides -1, vitamin E, olive oil, Sodium Hyaluronate, panthenol, glycerine, 1,2- hexylene glycols and
Arginine.Chinese patent literature CN103732224A discloses a kind of composition for eyelash growth, including:Nipradilol
Or its pharmacy or cosmetically acceptable salt.But it is current also not on a kind of composition for promoting eyelashes growth of the invention
Appear in the newspapers.
The content of the invention
It is an object of the invention to provide a kind of composition for promoting eyelashes to grow;
It is a further object of the present invention to provide a kind of preparation method of the composition for promoting eyelashes to grow.
The purpose of the present invention is realized by following technical scheme:
The composition for promoting eyelashes to grow of the present invention, is prepared from by the raw material of following weight portion:Meadowrueleaf corydalis root 80
~150 parts, 1~5 part, dandelion 10-30 parts of Moschus.
Preferably, it is that the raw material of following weight portion is prepared from:100~120 parts of meadowrueleaf corydalis root, 2~3 parts of Moschus, Pu Gong
English 15-25 parts.
The following is the crude drug source of Chinese medicine preparation of the present invention:
Meadowrueleaf corydalis root, is the root of bloodroot meadowrueleaf corydalis root.【Nature and flavor】Hardship, it is cool.【Indication】Clearing heat and detoxicating, dampness removing, analgesic stops
Blood.
Moschus, is animal in deer family woods musk deer Moschus berezovskii Flerov, horse musk deer Moschus sifanicus
Secretion is dried in the ripe hero body note capsules of Przewalski or original musk deer Moschus moschiferus Linnaeus.【Property
Taste】It is pungent, temperature.【Return through】The thoughts of returning home, the spleen channel.【Indication】Inducing resuscitation of having one's ideas straightened out, invigorate blood circulation, swelling and pain relieving.For pyreticosis coma, in
Wind phlegm is fainted, bstruction of the circulation of vital energy is fainted cruelly, middle evil is gone into a coma, Amenorrhea , wei lumps in the abdomen, and stillborn foetus of having difficult labour, trusted subordinate sudden and violent pain, carbuncle swells scrofula, abscess of throat is fallen and flutters wound
Bitterly, numbness pain is numb.
Dandelion, is feverfew dandelion Taraxacum mongolicum Hand.-Mazz., alkali ground dandelion
Taraxacum sinicum Kitag. or belong to several plants together dry herb.【Nature and flavor】It is bitter, sweet, tremble with fear.【Return through】Return liver, stomach
Through.【Indication】It is clearing heat and detoxicating, dispersing swelling and dissipating binds, inducing diuresis for treating strangurtia.For furuncle swelling toxin, acute mastitis, scrofula, hot eyes, pharyngalgia, lung
Carbuncle, acute appendicitis, jaundice with damp-heat pathogen, puckery pain of heat gonorrhea.
Another aspect of the present invention there is provided the preparation method of the active component of the present composition, and the method is to use
The ethanol of water extraction or 40-80% concentration expressed in percentage by volumes is extracted and is prepared from.Specific preparation method is as follows:
Scheme one:Take whole medicinal materials, extracting in water 2-3 times after mixing, each amount of water equivalent to 6-12 times of medicinal material gross weight,
Each extraction time is 1-3 hours, merges extract solution, is filtered, and relative density is 1.15-1.20 when filtrate is concentrated into 70-80 DEG C
Clear cream, obtain final product active component.
Scheme two:Whole medicinal materials are taken, is extracted 2-3 times with 40-80% alcohol refluxs after mixing, each ethanol consumption is medicinal material total amount
4-10 times, extraction time be 1-4 hour, merge extract solution, filter, relative density is when filtrate is concentrated into 70-80 DEG C
The clear cream of 1.15-1.20, obtains final product active component.
Scheme three:Whole medicinal materials are taken, extracting in water 2-3 times after mixing, 6- of each amount of water equivalent to medicinal material gross weight
12 times, each extraction time is 1-3 hours, merges extract solution, is filtered, and relative density is when filtrate is concentrated into 70-80 DEG C
The clear cream of 1.15-1.20, adds ethanol, makes alcohol content for 40-70%, stands 12-24 hours, and filtration, filtrate is concentrated into 70-80
DEG C when relative density for 1.10-1.25 medicinal extract, obtain final product active component.
The composition for promoting eyelashes to grow of the present invention, can match somebody with somebody with pharmacy or cosmetically-acceptable carrier
Close, be made the various external preparations for being directly applied to eyelash, such as liniment, drops, paste.
Pharmaceutically acceptable carrier of the invention includes but is not limited to following:
Diluent:Distilled water, olive oil etc..
Cosolvent:The polyalcohols such as glycerine, sorbierite.
Preservative:Benzoic acid, Sodium Benzoate, propionic acid, parabens, ethyl-para-hydroxybenzoate etc..
Oleaginous base:Vaseline, liquid paraffin, lanolin, beeswax, animal oil, vegetable oil, glycerin monostearate,
Octadecyl alcolol etc. and its mixture,
Water-soluble base:Glycerine, sodium alginate, carbopol resin, starch gelatin, methylcellulose, sodium carboxymethylcellulose,
Polyethylene glycol, polyvinyl alcohol.
Transdermal enhancer:Cutin moisturizing diuretin, pyrrolones derivative, linoleic acid, laruyl alcohol, tween, dodecyl front three
Base ammonium bromide, dodecyl sodium sulfate, lauryl sodium sulfate, menthol, Laurocapram(Azone)Deng.
For example, it can be prepared as various common exterior-applied formulations by one of following method:
Method 1:Liniment
Scheme one is taken one of to the gained active component of scheme three, adds liniment often to use auxiliary material, routinely production method is prepared into this
Invention liniment.
Above-mentioned liniment often includes one of diluent, preservative, cosolvent, transdermal enhancer or whole with auxiliary material.
Method 2:Paste
Scheme one is taken one of to the gained active component of scheme three, adds paste often to use auxiliary material, routinely production method is prepared into this
Invention paste.
Above-mentioned paste often includes one of oleaginous base, water-soluble base, preservative, transdermal enhancer or whole with auxiliary material.
Method 3:Drops
Scheme one is taken one of to the gained active component of scheme three, after dilution, is added water and is stirred evenly, after standing filtering, obtained final product.
The applicant combines modern medicine beauty experience on the basis of Traditional Chinese Medicine Coryza Treated by Syndrome Differentiation is studied, by for many years
Experiment, multiple formulations are screened, and be have found a kind of with the composition for promoting eyelashes growth.Inventive formulation is rationally created
Newly, wherein, meadowrueleaf corydalis root extract can excite the generation of collagen in eyelid skin, and eyelid skin can be made to hold eyelashes root
Portion, can significantly reduce eyelashes and drop;Moschus extract is promoting blood circulation and removing obstruction in channels, there is dredging and activation effect, activates hair follicle embryo, accelerates eyelash
Hair fast breeding, promotes eyelashes growth.Dandelion extract can nourish hair follicle, help promotion eyelashes to increase, and suppress fat granule
Growth.Full side has the absorption for promoting Eyelash follicle to nutritional ingredient, accelerates eyelashes fast breeding, increases eyelashes quantity, and energy
Prevent the effect of the growth of fat granule.
A kind of composition of promotion eyelashes growth that the present invention is provided has advantages below:
1st, the composition that the present invention is provided safely and effectively, with absorption of the Eyelash follicle to nutritional ingredient is promoted, accelerates eyelashes fast
Speed propagation, increases eyelashes quantity, and can prevent the effect of the growth of fat granule.Eczema body can be treated to itch, for treating in damp and hot
Accumulate eczema, the pruitus excellent curative for causing.
2nd, the composition that the present invention is provided, compared with control group, can dramatically increase eyelashes density, can remarkably promote eyelash
The growth of staple length.
3rd, present composition formula rationally innovation, low production cost, process is simple.
Specific embodiment
The present invention is further illustrated below by embodiment.It should be understood that embodiments of the invention are for illustrating
The present invention is rather than limitation of the present invention.Essence of the invention belongs to the present invention to the simple modifications that the present invention is carried out
Claimed scope.Unless otherwise indicated, the percentage of the amount of alcohol in the present invention is percentage by volume, and v/v represents solution
Volume ratio.
The liniment of embodiment 1
Weigh meadowrueleaf corydalis root 80g, Moschus 1g, dandelion 10g.Extracting in water 3 times, three times amount of water is respectively the 12 of medicinal material gross weight
Again, 8 times, 6 times, three extraction times are respectively 3 hours, 2 hours, 1 hour, merge extract solution, and filtration, filtrate is concentrated into 70 DEG C
When relative density be 1.25 clear cream, the percent by volume for adding 2 times of clear cream weight is 95% ethanol, is stirred evenly, and stands 48 small
When, filtration, filtrate recycling ethanol, relative density is 1.25 medicinal extract when being concentrated into 70 DEG C, and after adding olive oil, plus distilled water is adjusted
To 1000mL, stir evenly, stand 12h, refined filtration, packing obtains final product liniment of the present invention.
The drops of embodiment 2
Weigh meadowrueleaf corydalis root 150g, Moschus 5g, dandelion 30g.Extracted 3 times with 40% alcohol reflux, each ethanol consumption is respectively medicine
10 times, 8 times, 4 times of material total amount, extraction time is distinguished 3 hours, 2 hours, 1 hour, merges extract solution, filtering, filtrate concentration 60
DEG C when relative density be 1.25 medicinal extract, add water for injection, with filtering with microporous membrane, sterilizing, packing are obtained final product.
The drops of embodiment 3
Weigh meadowrueleaf corydalis root 100g, Moschus 2g, dandelion 15g.Extracting in water 3 times, three times amount of water is respectively equivalent to medicinal material gross weight
12 times, 8 times, 6 times of amount, each extraction time is distinguished 3 hours, 2 hours, 1 hour, merges extract solution, and filtration, filtrate is concentrated into
Relative density is 1.20 clear cream at 70 DEG C, adds ethanol, makes alcohol content be 40%, stands 24 hours, and filtration, filtrate is concentrated into
Relative density is 1.10 medicinal extract when filtrate is concentrated into 70 DEG C, adds water for injection, and with filtering with microporous membrane, sterilizing, packing are
.
The liniment of embodiment 4
Weigh meadowrueleaf corydalis root 120g, Moschus 3g, dandelion 25g.Extracted 2 times with alcohol reflux, each concentration of alcohol is respectively 80%,
60%, each ethanol consumption is respectively 10 times of medicinal material total amount, 8 times, and extraction time is respectively 4 hours, 3 hours, merges and extracts
Liquid, filtering, relative density is 1.10 medicinal extract when filtrate is concentrated into 80 DEG C, and after adding olive oil, plus distilled water is adjusted to 1000mL,
Stir evenly, stand 12h, refined filtration, packing obtains final product liniment of the present invention.
The paste of embodiment 5
Weigh meadowrueleaf corydalis root 110g, Moschus 3g, dandelion 20g.Extracting in water 2 times, twice amount of water be respectively medicinal material gross weight
10 times, 8 times, twice extraction time be respectively 2 hours, 1 hour, merge extract solution, filtration, filtrate is concentrated into relatively close at 80 DEG C
The medicinal extract for 1.10 is spent, it is standby.
Stearic acid 15g, vaseline 100g, lanolin 80g, glyceryl stearate 35g, hexadecanol 80g are weighed, is heated to
85 DEG C, stir evenly, it is standby as oil phase;Separately take glycerine 130g, ethyl-para-hydroxybenzoate 2g, lauryl sodium sulfate 20g, the moon
Osmanthus Azone 25g, adds above-mentioned thick paste and volatile oil, water use regulation to make oil, the common 1000g of water two-phase, as water phase, be heated to 90
DEG C, after after all dissolvings, constant temperature is stirred evenly to 85 DEG C;Oil phase is slowly added into water phase, stirring in refiner is put, cooling solidifies,
Packing, obtains final product paste of the present invention.
The paste of embodiment 6
Weigh meadowrueleaf corydalis root 140g, Moschus 4g, dandelion 23g.Extracting in water 2 times, each amount of water is respectively equivalent to medicinal material gross weight
12 times, 10 times of amount, each extraction time is respectively 3 hours, 2 hours, merges extract solution, and filtration, filtrate is concentrated at 80 DEG C
Relative density is 1.05 clear cream, adds ethanol, makes alcohol content be 70%, stands 12 hours, filtration, when filtrate is concentrated into 70 DEG C
Relative density is 1.25 medicinal extract, standby.
Stearic acid 18g, vaseline 100g, lanolin 80g, glyceryl stearate 30g, hexadecanol 82g are weighed, is heated to
85 DEG C, stir evenly, it is standby as oil phase;Separately take glycerine 110g, ethyl-para-hydroxybenzoate 4g, lauryl sodium sulfate 30g, the moon
Osmanthus Azone 30g, adds above-mentioned thick paste and volatile oil, water use regulation to make oil, the common 1000g of water two-phase, as water phase, be heated to 90
DEG C, after after all dissolvings, constant temperature is stirred evenly to 85 DEG C;Oil phase is slowly added into water phase, stirring in refiner is put, cooling solidifies,
Packing, obtains final product paste of the present invention.
Experimental example 1
80 volunteers of selection, the age between 18-35 Sui, is randomly divided into 2 groups, control group and test group, every group of each 40 will
Hope person.
Test group:The paste of the embodiment of the present invention 5;
Control group:Deionized water placebo.
It is continuous to use 8 weeks, smear once sooner or later daily.Record these volunteer upper eyelid eyelashes quantity and length, under
The quantity and length of eyelid eyelashes.
Eyelashes growth-promoting media of the invention is smeared with hairbrush be applied to upper and lower margo palpebrae and eyelashes root daily, continuous 8 weeks, often
It is smeared once sooner or later.Record quantity and length, the quantity and length of palpebra inferior eyelashes of these volunteer upper eyelid eyelashes.
Result of the test is shown in Table 1.
Table 1 promotes eyelashes growth result of the test
From the results shown in Table 1, compared with control group, the embodiment of the present invention 5 can dramatically increase eyelashes density, Neng Gouxian
Write the growth for promoting eyelash length.
Although above having used general explanation, specific embodiment and experiment, the present invention is made to retouch in detail
State, but on the basis of the present invention, it can be made some modifications or improvements, this is to those skilled in the art apparent
's.Therefore, these modifications or improvements without departing from theon the basis of the spirit of the present invention, belong to claimed
Scope.
Claims (8)
1. the composition that a kind of promotion eyelashes grow, it is characterised in that it is prepared from by the raw material of following weight portion:Rock
80~150 parts of the coptis, 1~5 part, dandelion 10-30 parts of Moschus.
2. the composition that promotion eyelashes as claimed in claim 1 grow, it is characterised in that it is the raw material system of following weight portion
Standby:100~120 parts of meadowrueleaf corydalis root, 2~3 parts, dandelion 15-25 parts of Moschus.
3. the composition that promotion eyelashes as claimed in claim 1 or 2 grow, it is characterised in that its active component is to use water
Carry or the ethanol extraction of 40-80% concentration expressed in percentage by volumes is prepared from.
4. the composition that promotion eyelashes as claimed in claim 3 grow, it is characterised in that its active component is by following
What method was prepared from:Whole medicinal materials are taken, extracting in water 2-3 times after mixing, 6- of each amount of water equivalent to medicinal material gross weight
12 times, each extraction time is 1-3 hours, merges extract solution, is filtered, and relative density is when filtrate is concentrated into 70-80 DEG C
The clear cream of 1.15-1.20, obtains final product active component.
5. the composition that promotion eyelashes as claimed in claim 3 grow, it is characterised in that its active component is by following
What method was prepared from:Whole medicinal materials are taken, is extracted 2-3 times with 40-80% alcohol refluxs after mixing, each ethanol consumption is medicinal material
4-10 times of total amount, extraction time is 1-4 hours, merges extract solution, is filtered, and relative density is when filtrate is concentrated into 70-80 DEG C
The clear cream of 1.15-1.20, obtains final product active component.
6. the composition that promotion eyelashes as claimed in claim 3 grow, it is characterised in that its active component is by following
What method was prepared from:Whole medicinal materials are taken, extracting in water 2-3 times after mixing, 6- of each amount of water equivalent to medicinal material gross weight
12 times, each extraction time is 1-3 hours, merges extract solution, is filtered, and relative density is 1.15- when filtrate is concentrated into 70-80 DEG C
1.20 clear cream, adds ethanol, makes alcohol content for 40-70%, stands 12-24 hours, and filtration, filtrate is concentrated into 70-80 DEG C of phase
It is the medicinal extract of 1.10-1.25 to density, obtains final product active component.
7. the composition that a kind of promotion eyelashes grow, the composition and pharmacy that promote eyelashes growth as described in claim 1 or 2
Or cosmetically-acceptable carrier is prepared and formed.
8. the composition that promotion eyelashes as claimed in claim 7 grow, wherein described composition is to be directly applied to eyelash
The formulation of hair.
Priority Applications (1)
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CN201611164280.5A CN106728001A (en) | 2016-12-16 | 2016-12-16 | It is a kind of to promote composition of eyelashes growth and preparation method thereof |
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Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102274291A (en) * | 2011-07-13 | 2011-12-14 | 黄荣 | Chinese medicinal preparation for treating stroke and production method thereof |
CN104666502A (en) * | 2015-02-10 | 2015-06-03 | 曾成锋 | Traditional Chinese medicine composition for treating eczemas and preparation method for traditional Chinese medicine composition |
-
2016
- 2016-12-16 CN CN201611164280.5A patent/CN106728001A/en active Pending
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102274291A (en) * | 2011-07-13 | 2011-12-14 | 黄荣 | Chinese medicinal preparation for treating stroke and production method thereof |
CN104666502A (en) * | 2015-02-10 | 2015-06-03 | 曾成锋 | Traditional Chinese medicine composition for treating eczemas and preparation method for traditional Chinese medicine composition |
Non-Patent Citations (1)
Title |
---|
潘颜选: "《民间单验方治疗常见病》", 28 February 2010, 金盾出版社 * |
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