CN105796424A - Acne-removing composition and application thereof to cosmetics - Google Patents
Acne-removing composition and application thereof to cosmetics Download PDFInfo
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- CN105796424A CN105796424A CN201610202762.9A CN201610202762A CN105796424A CN 105796424 A CN105796424 A CN 105796424A CN 201610202762 A CN201610202762 A CN 201610202762A CN 105796424 A CN105796424 A CN 105796424A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/368—Carboxylic acids; Salts or anhydrides thereof with carboxyl groups directly bound to carbon atoms of aromatic rings
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/738—Cyclodextrins
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/008—Preparations for oily skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/56—Compounds, absorbed onto or entrapped into a solid carrier, e.g. encapsulated perfumes, inclusion compounds, sustained release forms
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Abstract
The invention belongs to the field of cosmetics and particularly discloses acne-removing composition and an application thereof to cosmetics. The acne-removing composition is prepared from components in parts by mass as follows: 0.1-0.5 parts of a vitamin A palmitate active matter, 0.1-1 part of an azelaic acid active matter, 0.1-1 part of a salicylic acid active matter and 0.1-1 part of an Asiatic pennywort herb extract, wherein the vitamin A palmitate active matter, the azelaic acid active matter and the salicylic acid active matter adopt active matters prepared by coating vitamin A palmitate, azelaic acid and salicylic acid respectively. The skin care composition can well penetrate skin surface layers to be absorbed and enter deep layers; all the components are matched in a specific proportion, and multiple contained effect ingredients are blended and cooperate with one another, so that the composition can play comprehensive roles in stripping aged cutin, dredging pores, inhibiting bacteria, diminishing inflammations, controlling oil, promoting metabolism, clearing pigmentation caused by acne and has the excellent acne removal and skin care effect.
Description
Technical field
The invention belongs to cosmetic field, be specifically related to a kind of acne-removing composition and the application in cosmetics thereof.
Background technology
Comedo, has another name called acne, is a kind of chronic inflammation skin being apt to occur in face, breast, the hair follicle at back and sebaceous gland
Skin is sick.Its typical case's skin lesion shows as that powder is perverse, mound, pus trace, tuberosity and cyst.The generation of comedo and hypersteatosis, hair
The principal elements such as the blocking of capsule sebaceous gland duct, antibacterial infection and inflammatory reaction are closely related.Common, human body after adolescing
The level of interior androgen particularly testosterone raises rapidly, promotes that sebaceous gland is grown and produces a large amount of sebum；Pilosebaceous unit simultaneously
The dyskeratosis of conduit causes catheter blockage, dyssebacia, forms horn plug；Multiple-microorganism especially acne in hair follicle
Propionibacterium amount reproduction, the lipase that propionibacterium acnes produces decomposes sebum and generates free fatty；Chemotactic inflammation is thin simultaneously
Born of the same parents and medium, finally induce and increase the weight of inflammatory reaction.Comedo has a strong impact on appearance and the confidence of people, work, the life to people
The raw negative influence of life birth, therefore anti-acne is one of research focus of cosmetics.
The generation of comedo is directly related with the excessive secretion of the Rapid development of sebaceous gland and sebum, therefore in exploitation anti-acne
During cosmetics, the selection to oils and fats must be prudent, on the one hand, some oils and fatss have cause pox, such as white mineral oil, vaseline etc., can block up
Plug pore, the symptom of aggravation comedo；On the other hand, comedo skin is on the low side to moist cosmetic acceptance, easily feels
Product is greasy, and absorbability is the best.Therefore, acne-eliminating cosmetic preferably uses salubrious water-soluble material.
Azelaic Acid, molecular formula is HOOC (CH2)7-COOH, is slightly soluble in water.Research shows, Azelaic Acid has suppression gold Portugal
Aerobe and the works of anaerobe such as grape coccus, staphylococcus epidermidis, Pseudomonas aeruginosa, Candida albicans, propionibacterium acnes
With, when higher concentration (more than 250mmol L-1), above-mentioned antibacterial is had killing action；Additionally, contestable suppression dihydro
The enzyme process of testosterone, the skin oil and fat reducing the induction of dihydrotestosterone factor is too much, reduces skin surface free fatty and lipid
Composition；Also having anti-keratinous effect, its action principle is mainly due to reducing thread keratic synthesis, thus reduces follicular keratosis
Excessively；Azelaic Acid has selectively acting in abnormal melanocyte, suppresses its overactivity, alleviates pigmentation.
Vitamin A, is again retinol, is a kind of conventional cosmetic material.Vitamin A can add with blood circulation promoting
Fast metabolism, reduces pigmentation, it is also possible to repair injured corium, synthesizes new collagen protein, increases the elasticity of skin,
Slow down the aging of skin.Vitamin A is the most unstable, it is easy to oxidation Decomposition under light, air, high temperature, and to skin spinosity
Swash property.In order to reduce its unstability and zest, various method has the most been used to be changed into by vitamin A water-fast
Davitin A.
Salicylic acid is a kind of fat-soluble organic acid, and chemical entitled oxybenzoic acid is slightly soluble in water, has microorganism anti-
Bacterium property, can dissolve skin keratin, makes horny layer come off, and removes blocked up horny layer, dredging pore.
Herba Centellae extract, has another name called indialite Flos Nelumbinis, is the perennial herbaceous plant that crawls, originates in India, existing extensive point
It is distributed in all over the world.In India herbal medicine system, Herba Centellae tradition application in terms of scytitis and wound healing is continued to use
Thousand.
After numerous studies work conducted in the acne-eliminating cosmetic field that the present inventor is previously mentioned, go out
Being found that with expecting, specific anti-acne raw material the most known per se is with the ratio group in the range of determining very much
Closing, due to its significant potentiation and permeance property, the acne-removing composition obtained has the anti-acne effect being obviously improved, thus
Complete the present invention.
Summary of the invention
In place of shortcoming and defect for solution prior art, the primary and foremost purpose of the present invention is to provide a kind of anti-acne combination
Thing, described acne-removing composition has good acne-removing.
Another object of the present invention is to the application providing above-mentioned acne-removing composition in cosmetics.
The object of the invention is achieved through the following technical solutions:
A kind of acne-removing composition, described acne-removing composition contains each component of following mass parts: vitamin A palmitate is lived
Property thing 0.1-0.5 part, Azelaic Acid active matter 0.1-1 part, salicylic acid active matter 0.1-1 part, Herba Centellae extract 0.1-1 part；Its
Described in vitamin A palmitate active matter, Azelaic Acid active matter and salicylic acid active matter be respectively use beta-schardinger dextrin-bag
Wrap up in the active matter that vitamin A palmitate, Azelaic Acid and salicylic acid prepare.
An embodiment wherein, described acne-removing composition contains each component of following mass parts: vitamin A palmitate
Active matter 0.3 part, Azelaic Acid active matter 0.4 part, salicylic acid active matter 0.5 part, Herba Centellae extract 0.5 part；Wherein said
Vitamin A palmitate active matter, Azelaic Acid active matter and salicylic acid active matter are respectively and use beta-schardinger dextrin-parcel vitamin A
The active matter that cetylate, Azelaic Acid and salicylic acid prepare.
Preferably, described acne-removing composition can also be containing the component of following mass parts: pentanediol 0.5-1 part and Herba Menthae carry
Take thing 0.5-1 part.
Acne-removing composition described in an embodiment can also be containing the component of following mass parts wherein: pentanediol 0.8
Part, Folium Menthae extract 0.8 part.
Described pentanediol and Folium Menthae extract can play the comprehensive effect promoting infiltration, and Folium Menthae extract can also be composed
Give the refrigerant sense of product, the scorching hot sense of discomfort that easing whelk is brought.
Preferably, described acne-removing composition can also be containing the component of following mass parts: Radix Scutellariae extract 0.1-1 part, pellet
Conopsea extraction 0.1-1 part, Aloe extract 0.1-1 part and hamamelis extract 0.1-1 part.
Acne-removing composition described in an embodiment can also be containing the component of following mass parts wherein: Radix Scutellariae extract
0.5 part, Radix Salviae Miltiorrhizae extract 0.5 part, Aloe extract 0.5 part and hamamelis extract 0.5 part.
Vitamin A palmitate active matter of the present invention, Azelaic Acid active matter and salicylic acid active matter are that β-ring is stuck with paste
The active matter that spermatophore is wrapped up in, its object is to strengthen vitamin A palmitate, Azelaic Acid and salicylic water solublity, reduce skin
The zest of skin.Vitamin A palmitate active matter, Azelaic Acid active matter and salicylic acid active matter can be commercially available prod, excellent
Choosing, can prepare according to following technique:
(1) beta-schardinger dextrin-is dissolved in the water, adds ethanol；
(2) any one material in vitamin A palmitate or Azelaic Acid or salicylic acid is added, stirring；
(3) filter, by filtrate decompression evaporating ethanol；In drying in oven, to obtain final product.
In one of them embodiment of the present invention, the described vitamin A palmitate of beta-schardinger dextrin-parcel, Azelaic Acid and
The preparation technology of salicylic acid active matter is as follows:
(1) 1 mass parts beta-schardinger dextrin-is dissolved in 10 mass parts water, adds ethanol so that the content of ethanol is
40wt%；
(2) any one material in vitamin A palmitate or Azelaic Acid or salicylic acid, added material matter are added
Amount number is 3 parts, stirs 24 hours at a temperature of 30 DEG C；
(3) with 1000 mesh filter-cloth filterings, filtrate is evaporated under reduced pressure in 56 DEG C of water-baths removing ethanol；Dry in 50 DEG C of baking ovens
Dry, to obtain final product.
Vitamin A palmitate, Azelaic Acid and the salicylic acid active matter of the beta-schardinger dextrin-parcel obtained by this preparation technology
Envelop rate high, stability and water solublity are good.
Acne-removing composition of the present invention have stripping aging cutin, dredging pore, inhibiting bacteria and diminishing inflammation, control oil, enhance metabolism,
Remove the Pigmented all-dimensional multi-angle effect caused because of comedo, add the conventional substrate of skin care item or carrier, can make
Become the cosmetics such as facial film, Cleansing Foam, acne eliminating cream, anti-acne curry.
Present invention also offers a kind of anti-acne curry, comprise the component of following mass percent:
Wherein said vitamin A palmitate active matter, Azelaic Acid active matter and salicylic acid active matter respectively use β-ring
The active matter that dextrin parcel vitamin A palmitate, Azelaic Acid and salicylic acid prepare.
Compared with prior art, the present invention has the following advantages and beneficial effect:
The composite skin care product of the present invention can be good at being absorbed through skin surface, enters deep layer；Each component is pressed
Arrange in pairs or groups according to special ratios, rich in multiple efficacies composition be in harmonious proportion mutually, collaborative, stripping aging cutin, dredging can be played
Pore, inhibiting bacteria and diminishing inflammation, control oil, enhance metabolism, remove the Pigmented all-dimensional multi-angle effect caused because of comedo,
There is excellent anti-acne skin effect.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is described in further detail, but embodiments of the present invention are not limited to this,
For the technological parameter indicated the most especially or condition, can refer to routine techniques and carry out.
Methyl ester of the present invention, is a kind of preservative, the entitled methyl parahydroxybenzoate of INCI.
Embodiment 1
A kind of preparation technology of the vitamin A palmitate active matter of beta-schardinger dextrin-parcel:
(1) 1kg beta-schardinger dextrin-is dissolved in 10kg water, adds ethanol so that the content of ethanol is 40wt%；
(2) add vitamin A palmitate 3kg, stir 24 hours at a temperature of 30 DEG C；
(3) with 1000 mesh filter-cloth filterings, filtrate is evaporated under reduced pressure in 56 DEG C of water-baths removing ethanol；Dry in 50 DEG C of baking ovens
Dry, to obtain final product.
A kind of preparation technology of the Azelaic Acid active matter of beta-schardinger dextrin-parcel:
(1) 1kg beta-schardinger dextrin-is dissolved in 10kg water, adds ethanol so that the content of ethanol is 40wt%；
(2) add Azelaic Acid 3kg, stir 24 hours at a temperature of 30 DEG C；
(3) with 1000 mesh filter-cloth filterings, filtrate is evaporated under reduced pressure in 56 DEG C of water-baths removing ethanol；Dry in 50 DEG C of baking ovens
Dry, to obtain final product.
A kind of preparation technology of the salicylic acid active matter of beta-schardinger dextrin-parcel:
(1) 1kg beta-schardinger dextrin-is dissolved in 10kg water, adds ethanol so that the content of ethanol is 40wt%；
(2) add salicylic acid 3kg, stir 24 hours at a temperature of 30 DEG C；
(3) with 1000 mesh filter-cloth filterings, filtrate is evaporated under reduced pressure in 56 DEG C of water-baths removing ethanol；Dry in 50 DEG C of baking ovens
Dry, to obtain final product.
Embodiment 2
A kind of anti-acne curry, comprises the component of following mass percent:
Wherein said vitamin A palmitate active matter, Azelaic Acid active matter and salicylic acid active matter is embodiment 1 institute
The active matter of the beta-schardinger dextrin-parcel of preparation.
Preparation technology: first by 1,3-PD, methyl ester heating for dissolving, adds water, glycyrrhizic acid dipotassium, carbomer, nonyl two
Acid activity thing, salicylic acid active matter, be heated to 85 DEG C, and stirring and dissolving is uniform；Add triethanolamine, stir；Cool to 45
DEG C, it is sequentially added into vitamin A palmitate active matter, Herba Centellae extract, beta glucan, stirs.
Embodiment 3
A kind of anti-acne curry, comprises the component of following mass percent:
Wherein said vitamin A palmitate active matter, Azelaic Acid active matter and salicylic acid active matter is embodiment 1 institute
The active matter of the beta-schardinger dextrin-parcel of preparation.
Preparation technology: first by 1,3-PD, methyl ester heating for dissolving, adds water, glycyrrhizic acid dipotassium, carbomer, nonyl two
Acid activity thing, salicylic acid active matter, be heated to 85 DEG C, and stirring and dissolving is uniform；Add triethanolamine, stir；Cool to 45
DEG C, it is sequentially added into vitamin A palmitate active matter, Herba Centellae extract, beta glucan, stirs.
Embodiment 4
A kind of anti-acne curry, comprises the component of following mass percent:
Wherein said vitamin A palmitate active matter, Azelaic Acid active matter and salicylic acid active matter is embodiment 1 institute
The active matter of the beta-schardinger dextrin-parcel of preparation.
Preparation technology: first by 1,3-PD, methyl ester heating for dissolving, adds water, glycyrrhizic acid dipotassium, carbomer, nonyl two
Acid activity thing, salicylic acid active matter, be heated to 85 DEG C, and stirring and dissolving is uniform；Add triethanolamine, stir；Cool to 45
DEG C, it is sequentially added into vitamin A palmitate active matter, Herba Centellae extract, beta glucan, stirs.
Embodiment 5
A kind of anti-acne curry, comprises the component of following mass percent:
Wherein said vitamin A palmitate active matter, Azelaic Acid active matter and salicylic acid active matter is embodiment 1 institute
The active matter of the beta-schardinger dextrin-parcel of preparation.
Preparation technology: first by 1,3-PD, methyl ester heating for dissolving, adds water, pentanediol, glycyrrhizic acid dipotassium, card ripple
Nurse, Azelaic Acid active matter, salicylic acid active matter, be heated to 85 DEG C, and stirring and dissolving is uniform；Add triethanolamine, stir；Fall
Temperature, to 45 DEG C, is sequentially added into vitamin A palmitate active matter, Herba Centellae extract, beta glucan, stirs.
Embodiment 6
A kind of anti-acne curry, comprises the component of following mass percent:
Wherein said vitamin A palmitate active matter, Azelaic Acid active matter and salicylic acid active matter is embodiment 1 institute
The active matter of the beta-schardinger dextrin-parcel of preparation.
Preparation technology: first by 1,3-PD, methyl ester heating for dissolving, adds water, pentanediol, glycyrrhizic acid dipotassium, card ripple
Nurse, Azelaic Acid active matter, salicylic acid active matter, be heated to 85 DEG C, and stirring and dissolving is uniform；Add triethanolamine, stir；Fall
Temperature, to 45 DEG C, is sequentially added into vitamin A palmitate active matter, Herba Centellae extract, beta glucan, Folium Menthae extract, Radix Scutellariae
Extract, Radix Salviae Miltiorrhizae extract, Aloe extract, hamamelis extract, stir.
Embodiment 7
Experiment one, efficacy assessments
Anti-acne curry prepared by embodiment 2-6 being carried out efficacy assessments, and arranges comparative example 1-3, wherein comparative example 1 is
Commercially available anti-acne curry, comparative example 2-3 is prepared as follows:
The preparation of comparative example 2: a kind of anti-acne curry, comprises the component of following mass percent:
Wherein said vitamin A palmitate active matter, Azelaic Acid active matter and salicylic acid active matter is embodiment 1 institute
The active matter of the beta-schardinger dextrin-parcel of preparation.Preparation technology is with embodiment 2.
The preparation of comparative example 3: a kind of anti-acne curry, comprises the component of following mass percent:
Wherein said vitamin A palmitate active matter, Azelaic Acid active matter and salicylic acid active matter is embodiment 1 institute
The active matter of the beta-schardinger dextrin-parcel of preparation.Preparation technology is with embodiment 2.
The anti-acne curry of embodiment of the present invention 2-6 and comparative example 1-3 is carried out crowd try out, to evaluate its acne-removing.
Test object: each experimental group is 10 volunteers, 18-25 year, it is possible to by Normalization rule cosmetics, and cooperating personnel press
Requirement completes appraisal, has certain expressive faculty, the impression after energy actual response use；Test zone: at face head's pox；
Use: use every day twice, use 7 days continuously；Evaluation criterion: effective, effectively, invalid, wherein comedo substantially eliminates judgement
For effective；Part comedo eliminates and is judged as effectively；Comedo does not reduce or reduces inconspicuous, and it is invalid to be judged as.Concrete survey
Test result is shown in Table 1.
Table 1 anti-acne test evaluation table
| Effective | Effectively | Invalid | |
| Embodiment 2 | 6 | 3 | 1 |
| Embodiment 3 | 6 | 4 | 0 |
| Embodiment 4 | 7 | 2 | 1 |
| Embodiment 5 | 8 | 2 | 0 |
| Embodiment 6 | 9 | 1 | 0 |
| Comparative example 1 | 6 | 2 | 2 |
| Comparative example 2 | 2 | 3 | 5 |
| Comparative example 3 | 1 | 3 | 6 |
Knowable to upper table 1, embodiment 2-6 and commercially available prod comparative example 1 compare, and the anti-acne combination prepared by the present invention is described
Thing has good anti-acne effect；Embodiment 3 and comparative example 2-3 compare, and the vitamin A palmitate activity of the present invention is described
Thing, Azelaic Acid active matter, salicylic acid active matter and Herba Centellae extract are arranged in pairs or groups according to special ratios, rich in multiple efficacies
Composition is in harmonious proportion mutually, has collaborative anti-acne effect；Embodiment 2-4 compares with embodiment 5, and pentanediol and Folium Menthae extract are described
Compound can have anti-acne facilitation effect；Embodiment 2-4 compares with embodiment 6, and Radix Scutellariae extract, Radix Salviae Miltiorrhizae extract, reed are described
Luxuriant growth extract and hamamelis extract have obvious potentiation to the acne-removing of compositions.
Above-described embodiment is the present invention preferably embodiment, but embodiments of the present invention are not by above-described embodiment
Limit, the change made under other any spirit without departing from the present invention and principle, modify, substitute, combine, simplify,
All should be the substitute mode of equivalence, within being included in protection scope of the present invention.
Claims (10)
1. an acne-removing composition, it is characterised in that described acne-removing composition contains each component of following mass parts: vitamin A
Cetylate active matter 0.1-0.5 part, Azelaic Acid active matter 0.1-1 part, salicylic acid active matter 0.1-1 part, Herba Centellae extract
0.1-1 part；Wherein said vitamin A palmitate active matter, Azelaic Acid active matter and salicylic acid active matter is respectively and uses
The active matter that beta-schardinger dextrin-parcel vitamin A palmitate, Azelaic Acid and salicylic acid prepare.
Acne-removing composition the most according to claim 1, it is characterised in that described acne-removing composition contains following mass parts
Each component: vitamin A palmitate active matter 0.3 part, Azelaic Acid active matter 0.4 part, salicylic acid active matter 0.5 part, Herba Centellae
Extract 0.5 part；Wherein said vitamin A palmitate active matter, Azelaic Acid active matter and salicylic acid active matter is respectively
Use the active matter that beta-schardinger dextrin-parcel vitamin A palmitate, Azelaic Acid and salicylic acid prepare.
Acne-removing composition the most according to claim 1, it is characterised in that described acne-removing composition is possibly together with following mass parts
Component: pentanediol 0.5-1 part and Folium Menthae extract 0.5-1 part.
Acne-removing composition the most according to claim 1, it is characterised in that described acne-removing composition is possibly together with following mass parts
Component: pentanediol 0.8 part, Folium Menthae extract 0.8 part.
Acne-removing composition the most according to claim 1, it is characterised in that described acne-removing composition is possibly together with following mass parts
Component: Radix Scutellariae extract 0.1-1 part, Radix Salviae Miltiorrhizae extract 0.1-1 part, Aloe extract 0.1-1 part and hamamelis extract
0.1-1 part.
Acne-removing composition the most according to claim 1, it is characterised in that described acne-removing composition is possibly together with following mass parts
Component: Radix Scutellariae extract 0.5 part, Radix Salviae Miltiorrhizae extract 0.5 part, Aloe extract 0.5 part and hamamelis extract 0.5 part.
Acne-removing composition the most according to claim 1, it is characterised in that described vitamin A palmitate active matter, nonyl
Diacid active matter and salicylic acid active matter are the active matter of beta-schardinger dextrin-parcel, are prepared into for commercially available prod or according to following technique
Arrive:
(1) first beta-schardinger dextrin-is dissolved in the water, adds ethanol；
(2) any one material in vitamin A palmitate or Azelaic Acid or salicylic acid is added, stirring；
(3) filter, by filtrate decompression evaporating ethanol；Dry, to obtain final product.
Acne-removing composition the most according to claim 7, it is characterised in that described vitamin A palmitate active matter, nonyl
Diacid active matter and salicylic acid active matter are that the active matter of beta-schardinger dextrin-parcel prepares according to following technique:
(1) first 1 mass parts beta-schardinger dextrin-is dissolved in 10 mass parts water, adds ethanol so that the content of ethanol is 40wt%；
(2) any one material in vitamin A palmitate or Azelaic Acid or salicylic acid, added quality of material are added
Number is 3 parts, stirs 24 hours at a temperature of 30 DEG C；
(3) with 1000 mesh filter-cloth filterings, filtrate is evaporated under reduced pressure in 56 DEG C of water-baths removing ethanol；50 DEG C of drying, to obtain final product.
9. the acne-removing composition described in claim 1 is as the application of acne-eliminating cosmetic additive, and described acne-eliminating cosmetic is face
Film, Cleansing Foam, acne eliminating cream or anti-acne curry.
10. an anti-acne curry, it is characterised in that comprise the component of following mass percent:
Wherein said vitamin A palmitate active matter, Azelaic Acid active matter and salicylic acid active matter respectively use β-ring
The active matter that dextrin parcel vitamin A palmitate, Azelaic Acid and salicylic acid prepare.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610202762.9A CN105796424B (en) | 2016-03-31 | 2016-03-31 | A kind of acne-removing composition and its application in cosmetics |
Applications Claiming Priority (1)
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Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105796640A (en) * | 2016-04-19 | 2016-07-27 | 田春燕 | Traditional Chinese medicine composition and preparation with acne treatment function |
| CN106177100A (en) * | 2016-08-29 | 2016-12-07 | 欧标（广州）化妆品有限公司 | A kind of compositions with anti-acne effect and application thereof |
| CN107496190A (en) * | 2017-10-15 | 2017-12-22 | 广州汀兰生物科技有限公司 | A kind of whitening spot-eliminating composition and its application |
| CN108143639A (en) * | 2018-02-08 | 2018-06-12 | 成雨熙 | A kind of acne eliminating cream and preparation method thereof |
| CN108187070A (en) * | 2018-03-15 | 2018-06-22 | 山东滨州智源生物科技有限公司 | A kind of preparation method of azelaic acid HYDROXYPROPYL BETA-CYCLODEXTRIN inclusion compound |
| CN110227036A (en) * | 2019-05-21 | 2019-09-13 | 南京神奇科技开发有限公司 | A kind of raw material used for cosmetic and preparation method thereof |
| CN110917060A (en) * | 2019-12-26 | 2020-03-27 | 厦门泽本健康管理有限公司 | Whitening and repairing acne removing lotion containing flavone compound and organic mixed acid |
| CN110946770A (en) * | 2020-01-16 | 2020-04-03 | 厦门泽本健康管理有限公司 | Acne-removing cream with liquid crystal structure and preparation method thereof |
| CN112587446A (en) * | 2020-12-31 | 2021-04-02 | 广州膜束生物科技有限公司 | Composition for treating acne and preparation method and application thereof |
| CN113081894A (en) * | 2021-05-06 | 2021-07-09 | 无锡元旭生物技术有限公司 | Soluble noninvasive acne-removing microneedle patch and preparation method thereof |
| CN113476336A (en) * | 2021-07-05 | 2021-10-08 | 广州美尔生物科技有限公司 | Acne-removing composition and preparation method and application thereof |
| CN115813823A (en) * | 2022-12-16 | 2023-03-21 | 中新国际联合研究院 | Liquid acne removal patch convenient to make up and preparation method and application thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104546808A (en) * | 2015-01-29 | 2015-04-29 | 珠海国佳新材股份有限公司 | Gel patch and preparation method thereof |
| CN104814921A (en) * | 2015-05-13 | 2015-08-05 | 朱敏 | Acne-removing scar-lightening mask solution, manufacturing method and acne-removing scar-lightening mask |
| CN105168478A (en) * | 2015-08-28 | 2015-12-23 | 无限极（中国）有限公司 | Skin care product and preparation method thereof |
-
2016
- 2016-03-31 CN CN201610202762.9A patent/CN105796424B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104546808A (en) * | 2015-01-29 | 2015-04-29 | 珠海国佳新材股份有限公司 | Gel patch and preparation method thereof |
| CN104814921A (en) * | 2015-05-13 | 2015-08-05 | 朱敏 | Acne-removing scar-lightening mask solution, manufacturing method and acne-removing scar-lightening mask |
| CN105168478A (en) * | 2015-08-28 | 2015-12-23 | 无限极（中国）有限公司 | Skin care product and preparation method thereof |
Non-Patent Citations (2)
| Title |
|---|
| 吴志明等 主编: "《中医美容皮肤科学》", 31 December 2015, 中国中医药出版社 * |
| 吴旖主编: "《药物制剂生产》", 30 June 2015, 广东高等教育出版社 * |
Cited By (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105796640A (en) * | 2016-04-19 | 2016-07-27 | 田春燕 | Traditional Chinese medicine composition and preparation with acne treatment function |
| CN106177100A (en) * | 2016-08-29 | 2016-12-07 | 欧标（广州）化妆品有限公司 | A kind of compositions with anti-acne effect and application thereof |
| CN107496190A (en) * | 2017-10-15 | 2017-12-22 | 广州汀兰生物科技有限公司 | A kind of whitening spot-eliminating composition and its application |
| CN108143639B (en) * | 2018-02-08 | 2021-05-07 | 广州美尔生物科技有限公司 | Acne removing cream and preparation method thereof |
| CN108143639A (en) * | 2018-02-08 | 2018-06-12 | 成雨熙 | A kind of acne eliminating cream and preparation method thereof |
| CN108187070A (en) * | 2018-03-15 | 2018-06-22 | 山东滨州智源生物科技有限公司 | A kind of preparation method of azelaic acid HYDROXYPROPYL BETA-CYCLODEXTRIN inclusion compound |
| CN110227036A (en) * | 2019-05-21 | 2019-09-13 | 南京神奇科技开发有限公司 | A kind of raw material used for cosmetic and preparation method thereof |
| CN110917060A (en) * | 2019-12-26 | 2020-03-27 | 厦门泽本健康管理有限公司 | Whitening and repairing acne removing lotion containing flavone compound and organic mixed acid |
| CN110946770A (en) * | 2020-01-16 | 2020-04-03 | 厦门泽本健康管理有限公司 | Acne-removing cream with liquid crystal structure and preparation method thereof |
| CN112587446A (en) * | 2020-12-31 | 2021-04-02 | 广州膜束生物科技有限公司 | Composition for treating acne and preparation method and application thereof |
| CN113081894A (en) * | 2021-05-06 | 2021-07-09 | 无锡元旭生物技术有限公司 | Soluble noninvasive acne-removing microneedle patch and preparation method thereof |
| CN113476336A (en) * | 2021-07-05 | 2021-10-08 | 广州美尔生物科技有限公司 | Acne-removing composition and preparation method and application thereof |
| CN115813823A (en) * | 2022-12-16 | 2023-03-21 | 中新国际联合研究院 | Liquid acne removal patch convenient to make up and preparation method and application thereof |
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