CN1067059C - 用于制备一种药物活性化合物的中间体 - Google Patents

用于制备一种药物活性化合物的中间体 Download PDF

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Publication number
CN1067059C
CN1067059C CN95193895A CN95193895A CN1067059C CN 1067059 C CN1067059 C CN 1067059C CN 95193895 A CN95193895 A CN 95193895A CN 95193895 A CN95193895 A CN 95193895A CN 1067059 C CN1067059 C CN 1067059C
Authority
CN
China
Prior art keywords
formula
methyl
compound
preparation
butyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN95193895A
Other languages
English (en)
Chinese (zh)
Other versions
CN1151734A (zh
Inventor
R·E·达格尔
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Publication of CN1151734A publication Critical patent/CN1151734A/zh
Application granted granted Critical
Publication of CN1067059C publication Critical patent/CN1067059C/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Lining Or Joining Of Plastics Or The Like (AREA)
  • Detergent Compositions (AREA)
  • Lubricants (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CN95193895A 1994-05-20 1995-05-04 用于制备一种药物活性化合物的中间体 Expired - Fee Related CN1067059C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24643194A 1994-05-20 1994-05-20
US08/246,431 1994-05-20

Publications (2)

Publication Number Publication Date
CN1151734A CN1151734A (zh) 1997-06-11
CN1067059C true CN1067059C (zh) 2001-06-13

Family

ID=22930661

Family Applications (1)

Application Number Title Priority Date Filing Date
CN95193895A Expired - Fee Related CN1067059C (zh) 1994-05-20 1995-05-04 用于制备一种药物活性化合物的中间体

Country Status (20)

Country Link
US (1) US5719293A (OSRAM)
EP (1) EP0850225B1 (OSRAM)
JP (1) JPH10500681A (OSRAM)
KR (1) KR100369417B1 (OSRAM)
CN (1) CN1067059C (OSRAM)
AT (1) ATE247091T1 (OSRAM)
AU (1) AU690270B2 (OSRAM)
BR (1) BR9507668A (OSRAM)
CZ (1) CZ289968B6 (OSRAM)
DE (1) DE69531507T2 (OSRAM)
DK (1) DK0850225T3 (OSRAM)
ES (1) ES2204950T3 (OSRAM)
HU (1) HU221905B1 (OSRAM)
MX (1) MX9605794A (OSRAM)
NO (1) NO306673B1 (OSRAM)
NZ (1) NZ285588A (OSRAM)
PL (1) PL185858B1 (OSRAM)
PT (1) PT850225E (OSRAM)
WO (1) WO1995032189A1 (OSRAM)
ZA (1) ZA954053B (OSRAM)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR011125A1 (es) * 1997-02-14 2000-08-02 Smithkline Beecham Corp Procedimiento para preparar eprosartano

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1214324A (fr) * 1957-11-16 1960-04-07 Merck Ag E Procédé de préparation du pyridoxal et de ses dérivés à groupe aldéhyde protégé
US3798172A (en) * 1969-05-26 1974-03-19 Dan River Inc Dyeing textile materials with vat and sulfur dyes and reducing agent stabilizers for same
JPS518934B2 (OSRAM) * 1972-02-04 1976-03-22
US4024067A (en) * 1976-01-07 1977-05-17 The United States Of America As Represented By The Secretary Of The Navy Processes for the preparation of bis-benzoins and bis-benzils
JPS55104254A (en) * 1979-02-05 1980-08-09 Kuraray Co Ltd N-substituted-alpha-cyano-3-phenoxybenzylamine
JPS55167274A (en) * 1979-06-14 1980-12-26 Banyu Pharmaceut Co Ltd Forphenicine derivative and its preparation
JPS5671074A (en) * 1979-11-12 1981-06-13 Takeda Chem Ind Ltd 1,2-disubstituted-4-halogenoimidazole-5-acetic acid derivative
US5185351A (en) * 1989-06-14 1993-02-09 Smithkline Beecham Corporation Imidazolyl-alkenoic acids useful as angiotensin II receptor antagonists
JP2568315B2 (ja) * 1989-06-30 1997-01-08 イー・アイ・デュポン・ドゥ・ヌムール・アンド・カンパニー 縮合環アリール置換イミダゾール
JPH03112940A (ja) * 1989-09-26 1991-05-14 Nkk Corp （±）―４―ホルミル―α―アルキルベンジルアルコール類の製造方法

Also Published As

Publication number Publication date
JPH10500681A (ja) 1998-01-20
NO964921D0 (no) 1996-11-19
CN1151734A (zh) 1997-06-11
BR9507668A (pt) 1997-10-07
HU221905B1 (hu) 2003-02-28
PL317538A1 (en) 1997-04-14
DK0850225T3 (da) 2003-12-01
WO1995032189A1 (en) 1995-11-30
NO964921L (no) 1996-11-20
DE69531507T2 (de) 2004-06-17
NZ285588A (en) 1997-12-19
HUT75714A (en) 1997-05-28
US5719293A (en) 1998-02-17
PT850225E (pt) 2003-11-28
HK1014939A1 (en) 1999-10-08
EP0850225B1 (en) 2003-08-13
ZA954053B (en) 1996-01-19
MX9605794A (es) 1997-12-31
ATE247091T1 (de) 2003-08-15
EP0850225A4 (OSRAM) 1998-07-01
EP0850225A1 (en) 1998-07-01
CZ340396A3 (en) 1997-03-12
AU690270B2 (en) 1998-04-23
DE69531507D1 (de) 2003-09-18
PL185858B1 (pl) 2003-08-29
HU9603205D0 (en) 1997-01-28
AU2473795A (en) 1995-12-18
ES2204950T3 (es) 2004-05-01
CZ289968B6 (cs) 2002-05-15
NO306673B1 (no) 1999-12-06
KR100369417B1 (ko) 2003-04-23

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Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
C17 Cessation of patent right
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20010613

Termination date: 20110504