CN106661039B - 酪氨酸蛋白质激酶2(tyk2)抑制剂和其用途 - Google Patents

酪氨酸蛋白质激酶2(tyk2)抑制剂和其用途 Download PDF

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CN106661039B
CN106661039B CN201580021113.2A CN201580021113A CN106661039B CN 106661039 B CN106661039 B CN 106661039B CN 201580021113 A CN201580021113 A CN 201580021113A CN 106661039 B CN106661039 B CN 106661039B
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compound
nitrogen
sulfur
disorder
oxygen
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CN106661039A (zh
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卡格·E·玛斯
杰诺米·罗伯特·葛林伍德
多娜·L·罗曼罗
吉瑞狄恩·C·哈瑞玛
罗讷德·T·威斯特
蜜·莎丽
乔舒亚·杰米尔·肯尼迪-史密斯
马库斯·道葛林
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Takeda Pharmaceutical Co Ltd
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Lin Xu M Lakshmi Hakushi Co
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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
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    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN201580021113.2A 2014-02-28 2015-02-27 酪氨酸蛋白质激酶2(tyk2)抑制剂和其用途 Active CN106661039B (zh)

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Application Number Priority Date Filing Date Title
US201461946358P 2014-02-28 2014-02-28
US61/946,358 2014-02-28
US201461971376P 2014-03-27 2014-03-27
US61/971,376 2014-03-27
US201462096231P 2014-12-23 2014-12-23
US62/096,231 2014-12-23
PCT/US2015/018071 WO2015131080A1 (en) 2014-02-28 2015-02-27 Tyk2 inhibitors and uses thereof

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US (3) US9340540B2 (enExample)
EP (2) EP3110820B1 (enExample)
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CN (1) CN106661039B (enExample)
AU (1) AU2015222865B2 (enExample)
CA (1) CA2940666C (enExample)
ES (1) ES2921874T3 (enExample)
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