CN106619355A - Moisturizing traditional Chinese medicinal composition and application thereof - Google Patents
Moisturizing traditional Chinese medicinal composition and application thereof Download PDFInfo
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/33—Cactaceae (Cactus family), e.g. pricklypear or Cereus
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/886—Aloeaceae (Aloe family), e.g. aloe vera
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8968—Ophiopogon (Lilyturf)
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8969—Polygonatum (Solomon's seal)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/898—Orchidaceae (Orchid family)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
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- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/55—Liquid-liquid separation; Phase separation
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
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Abstract
The invention specifically discloses a moisturizing traditional Chinese medicinal composition and application thereof. The traditional Chinese medicinal composition is prepared from rhizoma polygonati odorati, aloe, radix ophiopogonis, common bletilla tuber and cactus. A preparation method of the traditional Chinese medicinal composition comprises the following steps: weighing the traditional Chinese medicinal raw materials of rhizoma polygonati odorati, aloe, radix ophiopogonis, common bletilla tuber and cactus according to a mixture ratio; smashing the traditional Chinese medicinal composition; sieving; adding water or an ethanol solution as an extraction solvent; soaking; performing room temperature extraction by a high-pressure homogenization extractor; performing centrifugal separation and concentration on an extracting solution; adsorbing with macroporous resin; eluting with ethanol repeatedly; collecting eluent; concentrating; adding butanediol in a mass being the same as that of the extracting concentrated solution; filtering to obtain the traditional Chinese medicinal composition. Through the synergistic effect of the Chinese medicinal herbs, the comprehensive moisturizing effects of moistening the skin, enhancing the skin elasticity, enhancing the skin cell immunity, promoting the blood circulation and diminishing inflammation are achieved. When the traditional Chinese medicinal composition is used for preparing moisturizing cosmetics, the composition has the advantages of good immediate moisturizing effect and long-lasting moisturizing effect.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition of compounding, the Chinese medicine composition has moisture-keeping functions, can apply to protect
The preparation of humidifying cosmetic, belongs to cosmetic field.
Background technology
The most important process of beauty seeks to moisturizing.Particularly autumn and winter season, because air starts to become to be dried very much, plus
The morning and evening temperature difference it is big, weather gradually turns cold, and causes skin pore to shrink, and sebaceous gland and the sweat gland secretion of skin surface are reduced, from
And cause skin surface to be easy to lose moisture content.And the maximum reason of skin aging exactly moisture content is not enough, in addition autumn skin is new
Old metabolism is slow, so autumn wind is together, many people's has just played on the face wrinkle or mottle, acne, and original piebaldism, brown patch also can
Deepen, skin becomes drying, and subcutaneous fat is thickened, and skin is tight, or even peeling falls bits.So, moisture-keeping cosmetics are most basic
Skin care item, be best-selling cosmetics.
The wetting agent for using at present is substantially the additive of simple function, is only capable of playing moistening effect, it is impossible to meet consumption
Person strengthens skin elasticity, strengthens the demand such as skin barrier and blood circulation promoting, so exploitation is with multi-functional wetting agent tool
There are realistic meaning and good market prospect.
The content of the invention
It is an object of the invention to provide a kind of moisturizing Chinese medicine composition, the Chinese medicine composition can make keratodermatitis moisture long
Temporally keep full, stable, and skin elasticity can be strengthened, strengthen skin barrier and blood circulation promoting.
To achieve the object of the present invention, present invention employs following technical scheme：
A kind of moisturizing Chinese medicine composition, it is characterised in that be made up of the component of following percentage by weight：Rhizoma Polygonati Odorati 5-45%, Aloe 5-
40%, Radix Ophiopogonis 5-40%, Pseudobulbus Bletillae (Rhizoma Bletillae) 5-35%, Radix et Caulis Opuntiae Dillenii 5-35%.
Preferably, a kind of moisturizing Chinese medicine composition, it is characterised in that be made up of the component of following percentage by weight：Rhizoma Polygonati Odorati
30%, Aloe 20%, Radix Ophiopogonis 20%, the Pseudobulbus Bletillae (Rhizoma Bletillae) 15%, Radix et Caulis Opuntiae Dillenii 15%.
Preferably, a kind of moisturizing Chinese medicine composition, it is characterised in that be made up of the component of following percentage by weight：Rhizoma Polygonati Odorati
28%, Aloe 15%, Radix Ophiopogonis 15%, the Pseudobulbus Bletillae (Rhizoma Bletillae) 20%, Radix et Caulis Opuntiae Dillenii 22%.
Preferably, a kind of moisturizing Chinese medicine composition, it is characterised in that be made up of the component of following percentage by weight：Rhizoma Polygonati Odorati
35%, Aloe 18%, Radix Ophiopogonis 12%, the Pseudobulbus Bletillae (Rhizoma Bletillae) 18%, Radix et Caulis Opuntiae Dillenii 17%.
Preferably, a kind of moisturizing Chinese medicine composition, it is characterised in that be made up of the component of following percentage by weight：Rhizoma Polygonati Odorati
25%, Aloe 20%, Radix Ophiopogonis 15%, the Pseudobulbus Bletillae (Rhizoma Bletillae) 20%, Radix et Caulis Opuntiae Dillenii 20%.
Above-mentioned Chinese medicine composition preparation method：Raw material of Chinese medicine Rhizoma Polygonati Odorati, Aloe, Radix Ophiopogonis, the Pseudobulbus Bletillae (Rhizoma Bletillae), Radix et Caulis Opuntiae Dillenii are weighed by proportioning,
Above-mentioned Chinese medicine composition is crushed, is sieved, be 5 by liquid material mass ratio:1-30:1 adds water or ethanol solution as Extraction solvent,
After immersion 1-5h, extract at room temperature is carried out with high pressure homogenization method machine under 30-70MPa pressure, extracting solution is centrifuged, concentrates
Afterwards, with macroporous resin adsorption, with the multiple eluting of the ethanol of 10-95%, eluent is collected, is concentrated into the quality of extracting solution and Chinese medicine
Than for 1:0.1-1:10, add and the butanediol dissolving for extracting concentrated solution phase homogenous quantities, filter, Chinese medicine composition is obtained.
The present invention another object is that application of the above-mentioned moisturizing Chinese medicine composition in preparing cosmetics, it is characterised in that make up
Contain above-mentioned moisturizing Chinese medicine composition in product, its consumption is 0.01-40%, and preferable amount is 1-20%.Except containing above-mentioned moisturizing
Beyond Chinese medicine composition, can as suitably desired add the usual composition that suitable cosmetics are used, such as emollient, water, breast
The matrix components such as agent, preservative, essence, pigment.
The beneficial effect of above-mentioned moisturizing Chinese medicine composition：The present invention carries out moisturizing Chinese medicine using the theory of Chinese medical science of monarch
The prescription of compositionss.In this prescription, Rhizoma Polygonati Odorati is monarch drug, has functions that nourishing YIN to relieve dryness, promoting the production of body fluid to quench thirst, by nursing one's health in body
Portion's environment, reaches the purpose of skin care, and modern study result shows that Rhizoma Polygonati Odorati contains abundant polysaccharide, Vitamin A and nicotinic acid, energy
Enough strengthen human disease resistance, slow down aging.Radix Ophiopogonis and Aloe are ministerial drug, there is quench one's thirst of promoting the production of body fluid, the effect of nourishing the lung to arrest cough Radix Ophiopogonis,
Modern pharmacological research also indicates that, Radix Ophiopogonis mainly glycosides containing dwarf lilyturf, steroidal saponin, alkaloid, sitosterol, aminoacid, vitamin etc.,
With resisting fatigue, remove free radical, improve the effect such as cellular immune function；Aloe has the effect of heat-clearing and toxic substances removing, sterilization, has
Extraordinary moisturizing and holding skin elasticity effect.The Pseudobulbus Bletillae (Rhizoma Bletillae) is adjuvant drug, and the effect of with astringing to arrest bleeding, detumescence and promoting granulation, the modern times grind
Study carefully and also indicate that the Pseudobulbus Bletillae (Rhizoma Bletillae) has good therapeutic effect for the chapped skin that skin hydropenia causes.Radix et Caulis Opuntiae Dillenii is to make medicine, coordinating the actions of various ingredients in a prescription,
The effect of with promoting flow of QI and blood, heat-clearing and toxic substances removing, modern study result shows that Radix et Caulis Opuntiae Dillenii has extraordinary moisturizing and bacteriostasis,
For inflammation, cold injury have therapeutic effect very number.By above Chinese medicine synergism, reach skin care, strengthen skin
The comprehensive moisture-keeping efficacies such as elasticity, enhancing Skin Cell immunity, blood circulation promoting, antiinflammatory.
Specific embodiment
Below by way of specific embodiment come the present invention is further illustrated, but these embodiments simply to illustrate that,
It is not limitation of the present invention.
A kind of moisturizing Chinese medicine composition of embodiment 1（Ⅰ）
A kind of moisturizing Chinese medicine composition（Ⅰ）, it is characterised in that it is made up of the component of following percentage by weight：Rhizoma Polygonati Odorati 30%, Aloe
20%, Radix Ophiopogonis 20%, the Pseudobulbus Bletillae (Rhizoma Bletillae) 15%, Radix et Caulis Opuntiae Dillenii 15%.
A kind of moisturizing Chinese medicine composition of embodiment 2（Ⅱ）
A kind of moisturizing Chinese medicine composition（Ⅱ）, it is characterised in that it is made up of the component of following percentage by weight：Rhizoma Polygonati Odorati 28%, Aloe
15%, Radix Ophiopogonis 15%, the Pseudobulbus Bletillae (Rhizoma Bletillae) 20%, Radix et Caulis Opuntiae Dillenii 22%.
A kind of moisturizing Chinese medicine composition of embodiment 3（Ⅲ）
A kind of moisturizing Chinese medicine composition（Ⅲ）, it is characterised in that it is made up of the component of following percentage by weight：Rhizoma Polygonati Odorati 35%, Aloe
18%, Radix Ophiopogonis 12%, the Pseudobulbus Bletillae (Rhizoma Bletillae) 18%, Radix et Caulis Opuntiae Dillenii 17%.
A kind of moisturizing Chinese medicine composition of embodiment 4（Ⅳ）
A kind of moisturizing Chinese medicine composition（Ⅳ）, it is characterised in that it is made up of the component of following percentage by weight：Rhizoma Polygonati Odorati 25%, Aloe
20%, Radix Ophiopogonis 15%, the Pseudobulbus Bletillae (Rhizoma Bletillae) 20%, Radix et Caulis Opuntiae Dillenii 20%.
Chinese medicine composition preparation method described in embodiment 1-4：Raw material of Chinese medicine Rhizoma Polygonati Odorati, Aloe, Radix Ophiopogonis, white is weighed by proportioning
Splendid achnatherum, Radix et Caulis Opuntiae Dillenii, above-mentioned Chinese medicine composition is crushed, and is sieved, and is 12 by liquid material mass ratio:1 addition volume fraction is 50% ethanol
Solution after immersion 2h, carries out with high pressure homogenization method machine extract at room temperature, extracting solution Jing as Extraction solvent under 50MPa pressure
After centrifugation, concentration, with macroporous resin adsorption, with the multiple eluting of the ethanol of 10-95%, eluent is collected, be concentrated into extracting solution
It is 1 with the mass ratio of Chinese medicine:1, add and the butanediol dissolving for extracting concentrated solution phase homogenous quantities, filter, Chinese medicine composition is obtained
Thing.
Comparative example 1-5 single Chinese medicine extract
Rhizoma Polygonati Odorati, Aloe, Radix Ophiopogonis, the Pseudobulbus Bletillae (Rhizoma Bletillae), Radix et Caulis Opuntiae Dillenii are weighed respectively, is crushed, sieved, be respectively 12 by liquid material mass ratio:1 adds body
Fraction be 50% ethanol solution as Extraction solvent, after immersion 2h, carried out with high pressure homogenization method machine under 50MPa pressure
Extract at room temperature, extracting solution is centrifuged, concentrate after, with macroporous resin adsorption, with the multiple eluting of the ethanol of 10-95%, collection is washed
De- liquid, it is 1 to be concentrated into extracting solution with the mass ratio of Chinese medicine:1, add and the butanediol dissolving for extracting concentrated solution phase homogenous quantities,
Filter, Rhizoma Polygonati Odorati extract, Aloe extract, Radix Ophiopogonis extract, bletilla striata extract, Radix et Caulis Opuntiae Dillenii extract are obtained respectively.
The moistening effect evaluation of test example 1
1st, sample preparation is evaluated
The moisturizing Chinese medicine composition 5g prepared according to embodiment 1 and comparative example 1-5 is taken, in adding 95g deionized waters, dissolving is equal
Even, prepared mass fraction is 5% assessing sample solution.
2nd, evaluation methodology
According to light industry standard QB/T 4256-2011 cosmetics moisture-keeping efficacy evaluation guides, the moistening effect of determination sample.
Method of testing：Healthy volunteer 20, male 10, women 10, the age is 25-50 year.In isoperibol（22
±1℃）, relative humidity 50 ± 5%, after 1 hour of rest.Press（2.0±0.1）mg/ cm2Consumption sample is coated in experimenter's left hand
Inner forearm（4cm×4cm）With right forearm inner side（4cm×4cm）.Blank（Do not apply）Test simultaneously.It is being painted with sample respectively
0.5 hour of product, 1 hour, 2 hours, 4 hours, the degree of hydration state of 8 hours test skin.
3rd, evaluation result
Evaluation result degree of hydration meansigma methodss are represented, are shown in Table 1.
Table 1
Embodiment 1 and comparative example 1-5 results contrast find, after Chinese medicine compounding, degree of hydration compare single Chinese medicine obtain it is aobvious
Writing increases, and moisturizing persistency is also substantially improved, with long-lasting moisturization.Illustrate the Chinese medicine composition obtained through compounding
Between serve synergistic function.
The preparation of the moisturiser of embodiment 5
Table 2 provides a kind of moisturiser formula of the moisturizing Chinese medicine composition containing the present invention, the consumption mass fraction of each material
Table：
Table 2
Preparation method：80 DEG C of dissolving mix homogeneously of A phases, 80 DEG C of dissolving mix homogeneously of B phases, add before Cyclomethicone emulsifying
Enter B phases, B is added to A phases simultaneously homogenizing 5 minutes during emulsifying, C phases simultaneously homogenizing 2 minutes are added when being cooled to 50 DEG C, wrap after ageing 24h
Dress, you can.
The long-acting moisturizing emulsion of embodiment 6
Table 3 provides a kind of long-acting moisturizing emulsion formula of the moisturizing Chinese medicine composition containing the present invention, the consumption matter of each material
Amount fraction representation：
Table 3
Preparation method：80 DEG C of dissolving mix homogeneously of A phases, 80 DEG C of dissolving mix homogeneously of B phases, B phases, A during emulsifying are added before emulsifying by C
B phases simultaneously homogenizing 5 minutes are added to, D simultaneously homogenizing 2 minutes are added when being cooled to 50 DEG C, packed after ageing 24h, you can.
Claims (2)
1. a kind of moisturizing Chinese medicine composition, it is characterised in that be made up of the component of following percentage by weight：Rhizoma Polygonati Odorati 5-45%, Aloe
5-40%, Radix Ophiopogonis 5-40%, Pseudobulbus Bletillae (Rhizoma Bletillae) 5-35%, Radix et Caulis Opuntiae Dillenii 5-35%；The Chinese medicine composition preparation method：In weighing by proportioning
Medicine raw material Rhizoma Polygonati Odorati, Aloe, Radix Ophiopogonis, the Pseudobulbus Bletillae (Rhizoma Bletillae), Radix et Caulis Opuntiae Dillenii, above-mentioned Chinese medicine composition is crushed, and is sieved, and is 5 by liquid material mass ratio:1-
30:1 adds water or ethanol solution as Extraction solvent, after immersion 1-5h, high pressure homogenization method machine is used under 30-70MPa pressure
Carry out extract at room temperature, extracting solution is centrifuged, concentrate after, with macroporous resin adsorption, with the multiple eluting of the ethanol of 10-95%, receive
Collection eluent, it is 1 to be concentrated into extracting solution with the mass ratio of Chinese medicine:0.1-1:10, add and extract concentrated solution phase homogenous quantities
Butanediol dissolves, and filters, and Chinese medicine composition is obtained.
2. a kind of application of the moisturizing Chinese medicine composition described in claim 1 in preparing cosmetics, it is characterised in that cosmetics
In 0.01-40% is calculated as with mass fraction containing a kind of moisturizing Chinese medicine composition described in claim 1, its consumption.
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| CN107095828A (en) * | 2017-07-03 | 2017-08-29 | 四川省中医药科学院 | A kind of daily chemical product composition with skin barrier repair function and its production and use |
| CN109078119A (en) * | 2018-10-17 | 2018-12-25 | 广东轻工职业技术学院 | A kind of moisturizing delay aging drug composition and its application |
| CN109350584A (en) * | 2018-10-17 | 2019-02-19 | 广东轻工职业技术学院 | A kind of potent moisturizing Chinese medicine composition fermentation magma and preparation and application |
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Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107095828A (en) * | 2017-07-03 | 2017-08-29 | 四川省中医药科学院 | A kind of daily chemical product composition with skin barrier repair function and its production and use |
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| CN109078119A (en) * | 2018-10-17 | 2018-12-25 | 广东轻工职业技术学院 | A kind of moisturizing delay aging drug composition and its application |
| CN109350584A (en) * | 2018-10-17 | 2019-02-19 | 广东轻工职业技术学院 | A kind of potent moisturizing Chinese medicine composition fermentation magma and preparation and application |
| CN109350584B (en) * | 2018-10-17 | 2022-12-13 | 广州市孝真生物科技有限公司 | Fermented raw juice of traditional Chinese medicine composition with powerful moisturizing effect and preparation and application thereof |
| CN116869895A (en) * | 2023-07-27 | 2023-10-13 | 广州悦荟化妆品有限公司 | Composition for promoting aquaporin expression and enhancing barrier, and preparation and application thereof |
| CN116869895B (en) * | 2023-07-27 | 2024-04-30 | 广州悦荟化妆品有限公司 | Composition for promoting aquaporin expression and enhancing barrier, and preparation and application thereof |
| CN117281761A (en) * | 2023-11-24 | 2023-12-26 | 清远市望莎生物科技有限公司 | Amino acid composition for promoting expression of aquaporin 3, application and daily chemical product |
| CN117281761B (en) * | 2023-11-24 | 2024-01-16 | 清远市望莎生物科技有限公司 | Amino acid composition for promoting expression of aquaporin 3, application and daily chemical product |
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