CN106511762A - Mica healthcare wine with effect of reinforcing kidneys to strengthen yang and preparation method thereof - Google Patents
Mica healthcare wine with effect of reinforcing kidneys to strengthen yang and preparation method thereof Download PDFInfo
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Abstract
The invention discloses mica healthcare wine with the effect of reinforcing the kidneys to strengthen yang and a preparation method thereof. The mica healthcare wine is prepared from mica, herba cistanche, morinda officinalis fruits, the fruit of Chinese wolfberry, rhizoma polygonati, the bark of eucommia, raspberries, fructus rosae laevigatae, Chinese chive seeds, flowers of kudzuvine, semen hoveniae and liquorice roots. The flowers of kudzuvine, semen hoveniae and other medicinal and edible homologous traditional Chinese medicine with the effects of dispelling the effects of alcohol and protecting the liver are compounded on the basis of reinforcing the kidneys to strengthen yang, the mica wine has the effect of reinforcing the kidneys to strengthen yang, damage of alcohol to the liver is reduced, and the treatment effect on kidney-yang deficiency patients, especially erectile dysfunction patients is remarkable.
Description
Technical field
The present invention relates to field of health care wine, and in particular to a kind of Maca health wine of kidney invigorating and YANG supporting and preparation method thereof.
Background technology
Insufficiency of kidney-YANG is more by innate deficiency of YANG in the body, or old deficiency of the kidney, or prolonged illness is impairment of the kidney, and the factor such as excess of sexual intercourse causes, and faces
Bed performance：Soreness of the waist and knees, aversion to cold and cold limbs, especially with lower limb as very, the vertigo, lethargy, pale complexion, or it is dark, light red tongue is fat
Tongue is white, deep and weak pulse or sexual impotence, women's infertility, or stool chronic diarrhea is more than, aqueous-grainy diarrhea, Diarrhoea, or edema, below waist
For very, by recessed filling do not rise, very then abdominal part distending pain, cardiopalmus cough with asthma.With the continuous quickening of rhythm of life, social pressure constantly increases
Plus, insufficiency of kidney-YANG patient numbers constantly rise, especially male insufficiency of kidney-YANG patient of the clinical manifestation for sexual impotence.According to incompletely statistics,
The sickness rate of adult male sexual impotence is up to 20%, and the sickness rate of the impotence more than more than 40 years old surpasses 50%.Insufficiency of kidney-YANG disease
Great damage is brought to the body and psychology of extensive patients, its work and life is had a strong impact on.Market occurs in that many benefits at present
The health promoting wine of kidney and enhancing body is used for treating insufficiency of kidney-YANG.Relatively common health care medicinal liquor for tonifying kidney, such as deer antler wine, strength wine, male silkworm moths spirit, three
Whip wine etc., but these medicated wine are only capable of playing the metabolic effect of regulation, to treating the effect of the symptoms such as insufficiency of kidney-YANG impotence and premature ejaculation
Fruit is not obvious.
Modern medicine study shows, Lepidinm meyenii Walp (Maca), acrid in the mouth, micro- peppery, heat warm in nature, return lung, kidney channel, used as a kind of medicine food two
With plant, with kidney-replenishing, benefiting essence-blood, resisting fatigue, improve fertility the effects such as, the various aminoacid rich in needed by human body, work
Property enzyme, mineral, trace element and physiologically active secondary metabolite, the equilibrium between yin and yang of scalable human body, promote blood follow
Ring, nourishing YIN and invigorating YANG effectively prevent and improve yang deficiency trembled with fear.Therefore, in view of Lepidinm meyenii Walp has above-mentioned pharmacological action, the country carries out
A large amount of researchs with regard to Lepidinm meyenii Walp healthy medicated wine, improve effect that healthy medicated wine treats insufficiency of kidney-YANG disease, such as：
Chinese invention patent CN102787062B discloses a kind of Flos abelmoschi manihot Maca wine, it by pueraria root powder, Abelmoschus esculentus, Penis et testis cervi,
Sanguis Cornu Cervi Pantotrichum, Fructus Lycii, Arillus Longan, Ligamentum cervi, crystal sugar, base liquor and water are made to scale, are given birth to sexual function, increase is improved
Power, endocrine regulation, delay the functions such as climacteric, enhancing immunity, fatigue alleviating.
Chinese invention patent CN104263602A discloses a kind of Lepidinm meyenii Walp Testis Et penis Bovis seu Bubali health promoting wine, including following weight portion into
Point：60～85 parts of Lepidinm meyenii Walp, 15～40 parts of Testis Et penis Bovis seu Bubali.Lepidinm meyenii Walp is carried out into the extraction of effective ingredient, Testis Et penis Bovis seu Bubali is made during powder is added to wine and mixed
Lepidinm meyenii Walp Testis Et penis Bovis seu Bubali wine is made in conjunction, the effects such as with sexual function, tonifying yang and enriching blood, health invigorating is improved.
Chinese invention patent application CN201610232173.5 discloses a kind of Maca composite health preserving wine, by Lepidinm meyenii Walp, Fructus Lycii,
Arillus Longan, Fructus Rubi, Cortex Cinnamomi and Fructus Mori are individually extracted from different wine degree Chinese liquor respectively, by each single extract according to a certain percentage
It is combined, Jing drops degree after combination, standing, membrane filtration, the allotment of big wine, fine straining and the step such as canned form Maca composite health preserving
Wine, the wine have resisting fatigue, improve energy the effects such as.
The studies above shows that health promoting wine prepared by Lepidinm meyenii Walp and other compositions rational proportion can be played really and improves sexual function, taste
The effect of cloudy YANG invigorating, but the unsuitable long-term drink of existing Maca wine, have into after liver because drinking and being easily caused ethanol
Noxious material " acetaldehyde ", causes liver dysfunction, and The liver and the kidney have a common source, essence and blood is mutually changed, and liver blood can nourish kidney essense, therefore the prosperity and decline pair of liver blood
The metaplasia of kidney essense is played an important role especially, so the damage of liver will affect the function of kidney.For this purpose, research and development are a both to have had Bu Shen Zhuang
The positive effect and Maca health wine of non-impairing the liver is significant.
The content of the invention
It is an object of the invention to overcome the deficiencies in the prior art, there is provided a kind of Maca health wine of kidney invigorating and YANG supporting
And preparation method thereof.Maca health wine of the present invention has compounded the relieving alcoholism and protecting the liver such as Flos puerariae lobatae, Japanese raisintree fruit on the basis of kidney invigorating and YANG supporting
Integration of edible and medicinal herbs Chinese medicine so that while Maca wine of the present invention has efficacies of tonifying kidney and invigorating yang, reduces damage of the ethanol to liver again, special
Not Shi He insufficiency of kidney-YANG patient take.
A kind of Maca health wine of kidney invigorating and YANG supporting of the present invention, its raw material include Lepidinm meyenii Walp, Herba Cistanches, Radix Morindae Officinaliss, Fructus Lycii, Huang
Essence, the Cortex Eucommiae, Fructus Rubi, Fructus Rosae Laevigatae, leek seed, Radix Glycyrrhizae.
In above-mentioned raw materials：Herba Cistanches sweet in the mouth, it is salty, it is warm in nature, there is kidney-replenishing, benefiting essence-blood, intestine moistening road, Herba Cistanches medicine
Food is dual-purpose, and modern medicine proves that Herba Cistanches are rich in several amino acids, and needed by human body trace element is built up resistance, resisting fatigue
Effect, while and the sexuality of the mankind and animal can be strengthened, the sexual organs such as male's kidney, testis, penis, spongy body are had
Great tonification effect, Alxa Badanjilin Desert Herba Cistanches quality are superior.Radix Morindae Officinaliss have strength resisting fatigue, activity
Ability strengthens, and improves cell hypoxia ability, extends the hypoxic tolerance time, the fear of cold symptom caused by antagonism insufficiency of kidney-YANG, warming and recuperating the kidney-YANG,
The kidney invigorating is healthy and strong, and overcomes sexual dysfunction, improves Sexual potency, the effects such as dramatically increase the weight of thymus and spleen, enhancing immunity.
Fructus Lycii has the kidney invigorating and essence nourishing, nourishing the liver to improve visual acuity, blood-enriching tranquillizing, promoting the production of body fluid to quench thirst, the effect of nourishing the lung to arrest cough and effect.Primary treatment is controlled
Hepatic and renal YIN deficiency, soreness of the waist and knees, dizzy, dizzy, many tears of blurred vision, cough due to consumptive disease are quenched one's thirst, the symptom such as seminal emission.There is Rhizoma Polygonati QI invigorating to support
The moon, spleen invigorating, lung moistening, kidney benefiting functions, for treating weakness of the spleen and stomach, fatigue and asthenia, xerostomia lack of appetite, deficiency of the lung cough caused by dryness, asthenia of essence and blood are interior
Heat such as is quenched one's thirst the disease.The Cortex Eucommiae its sweet in the mouth, it is warm in nature, there are liver and kidney tonifying, bone and muscle strengthening, Chong and Ren Meridians regulating, strengthen meridian and miscarriage prevention, can treat
The lumbago and skelalgia or aching and limp powerless that insufficiency of kidney-YANG causes, born of the same parents' tire that deficiency of liver-QI causes be not solid, the disease such as scrotum pruritus due to damp pathogen.Fructus Rubi cures mainly sexual impotence
Spermatorrhea, foul leukorrhea are infertile, kidney deficiency frequent urination and enuresis, visually dim, early whitening of beard and hair.Fruit of the Fructus Rosae Laevigatae for rosaceous plant Fructus Rosae Laevigatae,
Sour-puckery flavor, mild-natured, energy reinforcing the kidney and controlling nocturnal emission, reducing urination and antidiarrheal.Leek seed tool stomach invigorating, refresh oneself, the work(such as hidroschesis is astringent or styptic treatment for spontaneous sweating, reinforcing the kidney and supporting YANG, controlling nocturnal emission with astringent drugs
Effect.Radix glycyrrhizae taste is sweet, it is mild-natured and, enter the heart, spleen, lung, four Jing of stomach.It is raw with cooler, can eliminating fire and detoxication, relieving spasm to stop pain；Process and use partial temperature,
Exterior cold, invigorating the spleen and replenishing QI can be dissipated.Additionally, Radix Glycyrrhizae is also good at mediation property of medicine, the poison of hundred medicines is solved.
A kind of Maca health wine of kidney invigorating and YANG supporting of the present invention, its raw material also include Flos puerariae lobatae, Japanese raisintree fruit.Flos puerariae lobatae sweet in the mouth
Cool, function is relieved the effect of alcohol solution spleen, cures mainly heating excessive thirst of getting sick from drinking too much wine, anorexia, vomiting acid regurgitation.Japanese raisintree fruit sweet in the mouth is acid flat, energy heat clearing away, only
Yearningly, relieve the effect of alcohol, relieving restlessness, preventing or arresting vomiting are inverse, sharp defecation.Modern medicine study shows that Flos puerariae lobatae and Japanese raisintree fruit can significantly reduce ethanol in blood
Concentration in liquid, promotes the removing of ethanol, eliminates the excessive free radicals for producing in vivo after drinking, hinders the formation of lipid peroxide,
So as to mitigate damage of the ethanol to hepatic tissue, it is to avoid alcoholism causes various Developmental and Metabolic Disorder, various diseases are induced.
In Maca health wine of the present invention, each herbal medicine mutually can be cooperateed with, and interact, with kidney invigorating and YANG supporting, YIN nourishing profit
The effects such as lung, astringent sperm contracting urine, liver protection and eyesight, invigorating QI to consolidate the body surface resistance, resisting fatigue, heat-clearing and toxic substances removing, invigorating the spleen and regulating the stomach, strengthening the tendons and bones, especially fit
Close because caused by insufficiency of kidney-YANG, impotence patient is taken.
A kind of Maca health wine of kidney invigorating and YANG supporting of the invention described above, by weight, its raw material include 20～40 parts of Lepidinm meyenii Walp,
10～25 parts of Herba Cistanches, 10～15 parts of Radix Morindae Officinaliss, 12～20 parts of Fructus Lycii, 10～15 parts of Rhizoma Polygonati, 10～20 parts of the Cortex Eucommiae, Fructus Rubi
10～20 parts, 12～20 parts of Fructus Rosae Laevigatae, 10～20 parts of leek seed, 5～20 parts of Flos puerariae lobatae, 5～20 parts of Japanese raisintree fruit, 8～15 parts of Radix Glycyrrhizae.
Preferably, a kind of Maca health wine of kidney invigorating and YANG supporting, by weight, its raw material includes 30 parts of Lepidinm meyenii Walp, Herba Cistanches
20 parts, 15 parts of Radix Morindae Officinaliss, 15 parts of Fructus Lycii, 12 parts of Rhizoma Polygonati, 15 parts of the Cortex Eucommiae, 10 parts of Fructus Rubi, 15 parts of Fructus Rosae Laevigatae, leek seed 15
Part, 8 parts of Flos puerariae lobatae, 8 parts of Japanese raisintree fruit, 10 parts of Radix Glycyrrhizae.
The preparation method of the Maca health wine of above-mentioned kidney invigorating and YANG supporting, comprises the steps：A, by Lepidinm meyenii Walp, Herba Cistanches, Morinda offcinalis How
My god, Rhizoma Polygonati, the Cortex Eucommiae, Radix Glycyrrhizae chopping, be cut into 0.2～0.5cm of cross-sectional area2Fragment, with 30 DEG C～60 DEG C of temperature after cleaning
Drying；To dry after Fructus Lycii, Fructus Rubi, Fructus Rosae Laevigatae, leek seed, Flos puerariae lobatae, Japanese raisintree fruit cleaning；B, the component that step A is obtained
Wine vat is put into, according to 1：5～1：10 ratio adds Chinese liquor, and wine vat is sealed, and soaks 30～60 days, is fallen in immersion process daily
Cylinder 1～3 time；After C, soak time terminate, wine vat is opened, filtration obtains final product health promoting wine.The present invention causes medium-height grass using oven drying at low temperature
The effective elements of the medicine is retained.
Preferably, the alcoholic strength of the Chinese liquor is 42～70 °.The number of degrees of ethanol are closely bound up with the curative effect of medicated wine, unsuitable
It is too high or too low, though because the too high precipitation that can increase liposoluble constituent of Alcohol degree, is unfavorable for the dissolving of water soluble ingredient；
And the too low dissolving for being also unfavorable for liposoluble constituent of alcoholic strength, therefore suitable alcoholic strength extraction is selected just to can guarantee that medicated wine is treated
Effect.
Preferably, the alcoholic strength of the Chinese liquor is 65 ° so that negative and positive of the present invention are with benefit, kidney tonifying spermatogenesis and vital base and primordial QI consolidating
Kidney-replenishing formula plays the maximum property of medicine.
Preferably, the number of degrees of the health promoting wine are 35～62 °.This model can be made according to the difference of region, personal like etc.
Enclose interior different number of degrees Maca health wines.
The invention has the beneficial effects as follows：(1) present invention optimization health promoting wine formula, selected various Chinese herbal medicine, in kidney invigorating and YANG supporting
On the basis of compounded the integration of edible and medicinal herbs Chinese medicine of the relieving alcoholism and protecting the liver such as Flos puerariae lobatae, Japanese raisintree fruit, protection can be formed in liver, stomach during drinking of said product
Film, plays liver-protecting and stomach-nourishing effect, and passes through to accelerate urination, perspires to drain and decompose, and alleviates malaise symptoms of drinking, mitigates drunk journey
Degree, so that while Maca wine of the present invention has efficacies of tonifying kidney and invigorating yang, reduce damage of the ethanol to liver, be particularly suitable for again
Insufficiency of kidney-YANG patient take；(2) the selected rationally comprehensive Chinese herbal medicine compatibility of the present invention, wherein Lepidinm meyenii Walp, Herba Cistanches, Radix Morindae Officinaliss can be played
Kidney-replenishing, benefiting essence-blood, the effect of bone and muscle strengthening；Fructus Lycii, Rhizoma Polygonati, the Cortex Eucommiae can play a part of invigorating the liver and kidney, nourishing YIN and moistening the lung；Cover basin
Son, Fructus Rosae Laevigatae, leek seed have functions that astringent sperm contracting urine, temperature compensation Liver and kidney, tonifying YANG controlling nocturnal emission with astringent drugs；Flos puerariae lobatae, Japanese raisintree fruit can play hepatoprotective solution
Wine, alleviates the effect of the hepatic injury for causing of drinking；(3) the Maca health wine preparation method that the present invention is provided is by each medical herbs and Chinese liquor
Made by kidney invigorating and YANG supporting Maca wine, the comprehensive function of various medical materials can be played to greatest extent, with obvious kidney invigorating and YANG supporting, promoted
The autonomous spermatogenesis of kidney, fills vital essence, and constantly, blood flow is smooth for vigour, can supporing yang, replenishing vital essence and blood, liver and kidney tonifying, bone and muscle strengthening, so as to
Equilibrium between yin and yang is reached with the effect mended, curative effect is obvious；(4) the Maca health wine wine body by present invention preparation is soft, pure color,
It is sweet tasty and refreshing, all fragrant harmonies, yin yang complementarity, and the effect not dry with benefit, it is the preferable guarantor for integrating nutrition and drug effect
Strong good merchantable brand.Long-period drinking of said product, can strengthen body immunity, alleviating physical fatigue, and kidney invigorating and YANG supporting, treatment sexual impotence effect show
Write.
Specific embodiment
A kind of preparation method of the Maca health wine of kidney invigorating and YANG supporting of the present invention, comprises the steps：
A, by Lepidinm meyenii Walp, Herba Cistanches, Radix Morindae Officinaliss, Rhizoma Polygonati, the Cortex Eucommiae, Radix Glycyrrhizae chopping, be cut into 0.2～0.5cm of cross-sectional area2It is broken
Piece, is dried with 30 DEG C～60 DEG C of temperature after cleaning；By Fructus Lycii, Fructus Rubi, Fructus Rosae Laevigatae, leek seed, Flos puerariae lobatae, Japanese raisintree fruit cleaning
After dry；
B, the component that step A is obtained is put into into wine vat, according to 1：5～1：10 ratio adds 42～70 ° of Chinese liquor, by wine vat
Sealing, soaks 30～60 days, daily inverted engine 1～3 time in immersion process；
After C, soak time terminate, wine vat is opened, filtration obtains final product 35～62 ° of health promoting wine.
Preparation method of the present invention with natural medicine-food material as raw material, by select suitable wine degree, suitable solid-liquid ratio with
Chinese liquor carries out allocating, filters and make Maca health wine, not only given full play to enhancing immunity, resisting fatigue that raw material has,
The effects such as kidney invigorating and YANG supporting, astringent sperm contracting urine, hepatoprotective warming the stomach, strengthening the tendons and bones, and effect, fragrance and the mouthfeel of product is also assures that,
Also improve the stability of product.Empirical tests, the Maca health wine for preparing the present invention within the above range belong to the present invention most
Excellent preparation method, and each preparation method does not produce any shadow to effects of inventive formulation and ratio like products, nutrition
Ring, as health promoting wine mouthfeel differ only in wine (35～62 °) of the number of degrees it is different, drinking person can according to personal like selection phase
The health promoting wine of the number of degrees is answered, and the local flavor of health promoting wine is identical, therefore health care method for preparing medicated wine cited in the following embodiments is not
As the further restriction of the embodiment of the present invention.
Detect with regard to product index, various Maca health wines are prepared as sample using said method within the scope of the present invention
Product, the sense organ and physical and chemical index reached to sample according to national all standard detect that testing result is as shown in table 1：
The product index testing result of Maca health wine prepared by 1 present invention of table is as follows：
Below in conjunction with the embodiment of the present invention, technical scheme is clearly and completely described, it is clear that institute
The embodiment of description is only a part of embodiment of the invention, rather than the embodiment of whole.Based on the embodiment in the present invention,
The every other embodiment obtained under the premise of creative work is not made by those of ordinary skill in the art, belongs to this
The scope of bright protection.
Embodiment 1
A kind of Maca health wine of kidney invigorating and YANG supporting of the present invention, by weight, its raw material includes 40 parts of Lepidinm meyenii Walp, Herba Cistanches 10
Part, 10 parts of Radix Morindae Officinaliss, 12 parts of Fructus Lycii, 10 parts of Rhizoma Polygonati, 20 parts of the Cortex Eucommiae, 20 parts of Fructus Rubi, 12 parts of Fructus Rosae Laevigatae, 10 parts of leek seed,
5 parts of Flos puerariae lobatae, 5 parts of Japanese raisintree fruit, 8 parts of Radix Glycyrrhizae.
The preparation method of the Maca health wine of above-mentioned kidney invigorating and YANG supporting, comprises the steps：
A, by Lepidinm meyenii Walp, Herba Cistanches, Radix Morindae Officinaliss, Rhizoma Polygonati, the Cortex Eucommiae, Radix Glycyrrhizae chopping, be cut into 0.2～0.5cm of cross-sectional area2It is broken
Piece, is dried with 45 DEG C of temperature after cleaning；To dry in the air after Fructus Lycii, Fructus Rubi, Fructus Rosae Laevigatae, leek seed, Flos puerariae lobatae, Japanese raisintree fruit cleaning
It is dry；
B, the component that step A is obtained is put into into wine vat, according to 1：10 ratio adds 65 ° of Chinese liquor, and wine vat is sealed, and soaks
60 days, daily inverted engine 2 times in immersion process；
After C, soak time terminate, wine vat is opened, filtration obtains final product 52 ° of health promoting wine.
Embodiment 2
A kind of Maca health wine of kidney invigorating and YANG supporting of the present invention, by weight, its raw material includes 20 parts of Lepidinm meyenii Walp, Herba Cistanches 25
Part, 12 parts of Radix Morindae Officinaliss, 20 parts of Fructus Lycii, 15 parts of Rhizoma Polygonati, 10 parts of the Cortex Eucommiae, 15 parts of Fructus Rubi, 20 parts of Fructus Rosae Laevigatae, 20 parts of leek seed,
20 parts of Flos puerariae lobatae, 20 parts of Japanese raisintree fruit, 15 parts of Radix Glycyrrhizae.The preparation method of the present embodiment Maca health wine and the preparation method of embodiment 1
It is identical.
Embodiment 3
A kind of Maca health wine of kidney invigorating and YANG supporting of the present invention, by weight, its raw material includes 35 parts of Lepidinm meyenii Walp, Herba Cistanches 15
Part, 10 parts of Radix Morindae Officinaliss, 18 parts of Fructus Lycii, 10 parts of Rhizoma Polygonati, 15 parts of the Cortex Eucommiae, 15 parts of Fructus Rubi, 15 parts of Fructus Rosae Laevigatae, 15 parts of leek seed,
15 parts of Flos puerariae lobatae, 15 parts of Japanese raisintree fruit, 10 parts of Radix Glycyrrhizae.The preparation method of the present embodiment Maca health wine and the preparation method of embodiment 1
It is identical.
Embodiment 4
A kind of Maca health wine of kidney invigorating and YANG supporting of the present invention, by weight, 30 parts of Lepidinm meyenii Walp, 20 parts of Herba Cistanches, Radix Morindae Officinaliss
15 parts, 15 parts of Fructus Lycii, 12 parts of Rhizoma Polygonati, 15 parts of the Cortex Eucommiae, 10 parts of Fructus Rubi, 15 parts of Fructus Rosae Laevigatae, 15 parts of leek seed, 8 parts of Flos puerariae lobatae, trifoliate orange
Sub 8 parts, 10 parts of Radix Glycyrrhizae.The preparation method of the present embodiment Maca health wine is identical with the preparation method of embodiment 1.
Comparative example 1
A kind of Maca health wine, by weight, 46 parts of Lepidinm meyenii Walp, 20 parts of Herba Cistanches, 15 parts of Radix Morindae Officinaliss, 15 parts of Fructus Lycii,
12 parts of Rhizoma Polygonati, 15 parts of the Cortex Eucommiae, 10 parts of Fructus Rubi, 15 parts of Fructus Rosae Laevigatae, 15 parts of leek seed, 10 parts of Radix Glycyrrhizae.The system of the Maca health wine
Preparation Method is identical with the preparation method of embodiment 1.This comparative example and embodiment 4 differ only in dispensing in delete Flos puerariae lobatae and
Japanese raisintree fruit, improves the content of Lepidinm meyenii Walp, and the preparation method of health promoting wine is constant.
Comparative example 2
A kind of Maca health wine of kidney invigorating and YANG supporting of the present invention, by weight, 15 parts of Lepidinm meyenii Walp, 35 parts of Herba Cistanches, Radix Morindae Officinaliss
15 parts, 15 parts of Fructus Lycii, 12 parts of Rhizoma Polygonati, 15 parts of the Cortex Eucommiae, 10 parts of Fructus Rubi, 15 parts of Fructus Rosae Laevigatae, 15 parts of leek seed, 8 parts of Flos puerariae lobatae, trifoliate orange
Sub 8 parts, 10 parts of Radix Glycyrrhizae.This comparative example reduces the content of Lepidinm meyenii Walp with differing only in for embodiment 4 in dispensing, improve Herba Cistanches
Content, the preparation method of health promoting wine is constant.
Comparative example 3
A kind of Maca health wine of kidney invigorating and YANG supporting of the present invention, by weight, 30 parts of Lepidinm meyenii Walp, 20 parts of Herba Cistanches, Radix Morindae Officinaliss
15 parts, 15 parts of Fructus Lycii, 12 parts of Rhizoma Polygonati, 15 parts of the Cortex Eucommiae, 10 parts of Fructus Rubi, 15 parts of Fructus Rosae Laevigatae, 15 parts of leek seed, 16 parts of Flos puerariae lobatae,
10 parts of Radix Glycyrrhizae.This comparative example and embodiment 4 differ only in dispensing in substitute Japanese raisintree fruit, the preparation of health promoting wine completely with Flos puerariae lobatae
Method is constant.
Comparative example 4
A kind of Maca health wine of kidney invigorating and YANG supporting of the present invention, by weight, 30 parts of Lepidinm meyenii Walp, 20 parts of Herba Cistanches, Radix Morindae Officinaliss
15 parts, 15 parts of Fructus Lycii, 12 parts of Rhizoma Polygonati, 15 parts of the Cortex Eucommiae, 10 parts of Fructus Rubi, 15 parts of Fructus Rosae Laevigatae, 15 parts of leek seed, Japanese raisintree fruit 16
Part, 10 parts of Radix Glycyrrhizae.The Maca health wine and embodiment 4 differ only in dispensing in substitute Flos puerariae lobatae, health care completely with Japanese raisintree fruit
The preparation method of wine is constant.
First, sensory evaluation
Take equivalent above-described embodiment and the Maca health wine in comparative example makees sensory evaluation.Comparation and assessment mode adopts ten point system,
3 points of fragrance, 3 points of color and luster, 4 points of mouthfeel, select 10 experienced subjective appreciation persons and the mouthfeel of wine are passed judgment on, and according to total
Divide judged result, as a result see the table below 2：
2 tasting results of table are as follows：
As can be seen from Table 2, with the Maca health wine of the dispensing and its ratio preparation of the present invention conveniently, the health promoting wine
Medicine is fragrant to be coordinated with aroma, soft pure and sweet, long times of aftertaste, and especially 4 fragrance of embodiment and mouthfeel are optimal.
2nd, pharmacodynamics test
1 test material
1.1 test specimen：Entered as given the test agent from the embodiment cited by the present invention and comparative example Maca health wine
Row kidney invigorating and YANG supporting, Xing Yangqi flaccidity, the test of hepatoprotective effect assessment.
1.2 animal：Kunming mouse, 20 ± 2g of body weight；Wistar rats.
2nd, method and result
The impact of 2.1 couples of castration kidney deficiency rat accessory sex organs
2.1.1 the impact to castration male rat sexual organ
(1) male rat 70 is taken, 102～126g of body weight extracts bilateral testes, postoperative intramuscular injection penicillin, castration operation
Three days afterwards, 7 groups were divided at random, 10 per group, respectively castration model group, embodiment 1～4 and comparative example 1,2, continuous gavage
20d, daily 20ml, castration model group gavage normal saline, embodiment and the corresponding Maca health wine of comparative example group gavage；10 are taken separately
Only non-castrated rats same method breeding observing, used as Normal group.In 20d WQ-10B multipurpose electronics acupuncture point analyzers
Stimulating electrode be put in rat penis position, give electrode stimulating intensity 3mA, record eclipse period of penile erection is (from the beginning of stimulation
To the interval time of erection), the results are shown in Table 3.
The eclipse period of penile erection of 3 each group castration male rat of table
| Group | Eclipse period of penile erection (second) |
| Normal group | 16.98±0.82 |
| Castration matched group | 26.87±2.45 |
| Embodiment 1 | 21.32±0.88***# |
| Embodiment 2 | 22.15±0.83***# |
| Embodiment 3 | 21.96±0.86***# |
| Embodiment 4 | 21.03±0.82***# |
| Comparative example 1 | 22.52±1.02**# |
| Comparative example 2 | 25.42±1.24***# |
Note：Compare * * * P ＜ 0.01 with Normal group, compare #P ＜ 0.05 with castration model group.
As it can be seen from table 1 the Maca health wine prepared using inventive formulation can improve castration male rat penis
Irritability to outside stimuluss, with the effect for shortening male rat eclipse period of penile erection, being compared with castration model group is had
Significant difference (P ＜ 0.05), comparing with Normal group has pole significant difference (P ＜ 0.01).
(2) male rat 70 of the body weight in 100～110g is taken, castration is divided into 7 groups, 10 per group, respectively castration mould
Type group, 1～4 and comparative example 1,2, continuous gavage 20d, daily 20ml；Castration model group gavage normal saline, embodiment and contrast
The corresponding Maca health wine of example group gavage；10 non-castrated rats same method breeding observings are taken separately, as Normal group.20th
Animal is put to death after weighing by it, weighs rapidly seminal fluid capsule, prostate and preputial glandss weight, calculates per 100g body weight quantity, as a result
It is shown in Table 4.
Impact (X ± SD) of 4 Maca health wine of table to kidney deficiency animal model
| Group | Body weight (g) | Smart night capsule (mg) | Prostate (mg) | Preputial glandss (mg) |
| Normal group | 172.5±8.8 | 541.2±25.8 | 51.8±5.5 | 47.5±8.8 |
| Castration matched group | 162.2±6.9 | 37.8±8.0 | 7.2±0.6 | 3.4±1.6 |
| Embodiment 1 | 165.3±8.2 | 98.3±8.6* | 56.8±9.2* | 38.9±6.8* |
| Embodiment 2 | 164.1±7.9 | 96.8±8.5* | 55.4±9.1* | 36.8±7.6* |
| Embodiment 3 | 163.6±7.2 | 97.9±8.7* | 56.2±8.9* | 37.5±7.2* |
| Embodiment 4 | 168.4±8.0 | 99.7±8.9* | 58.8±8.7* | 39.3±7.9* |
| Comparative example 1 | 163.5±7.8 | 82.5±7.8* | 52.4±8.3* | 31.2±6.4* |
| Comparative example 2 | 162.9±8.6 | 80.4±7.4* | 51.6±8.6* | 30.8±6.1* |
Note：Compare * p ＜ 0.01 with castration model group.
As a result show：The body weight of kidney deficiency animal (castrated rats), each weight of reproductive organs are dynamic significantly lower than Normal group
Thing, illustrates kidney deficiency animal model success.The male rat seminal fluid capsule of gavage Maca health wine of the present invention, prostate, preputial glandss
Obviously higher than castration model group, weight illustrates that Maca health wine long-term taking of the present invention has the work for promoting male organs development
With.
2.1.2 the impact to Ovariectomized Female Rats accessory sex organ
Female rats 70 of the body weight in 100～110g are taken, bilateral ovaries are cut off under etherization, conventional antiinflammatory, 3 days
After be randomly divided into 7 groups, 10 per group, respectively castration model group, embodiment 1～4 and comparative example 1,2, continuous gavage 20d, often
Its 20ml；Castration model group gavage normal saline, embodiment and the corresponding Maca health wine of comparative example group gavage；Separately take 10 not going
Gesture rat same method breeding observing, used as Normal group.Animal is put to death after 20th day, weigh rapidly preputial glandss and bilateral
Uterus weight, calculates per 100g body weight quantity, the results are shown in Table 5.
Impact (X ± SD) of 5 Maca health wine of the present invention of table to Ovariectomized Female Rats
| Group | Preputial glandss (mg) | Uterus (mg) |
| Normal group | 42.8±8.7 | 74.4±12.5 |
| Castration matched group | 4.5±1.4 | 10.2±1.5 |
| Embodiment 1 | 39.8±9.2* | 72.3±8.5* |
| Embodiment 2 | 38.5±8.3* | 71.8±9.4* |
| Embodiment 3 | 38.2±8.9* | 71.1±8.7* |
| Embodiment 4 | 40.6±9.7* | 75.7±8.2* |
| Comparative example 1 | 35.4±8.8* | 69.5±7.8* |
| Comparative example 2 | 32.6±7.6* | 67.4±5.4* |
Note：Compare * p ＜ 0.01 with castration model group.
As a result show：The jenny preputial glandss of gavage Maca health wine of the present invention, the weight in uterus are obviously higher than going
Potential model group, illustrates that Maca health wine long-term taking of the present invention plays the role of to promote female organ development.
The impact of 2.2 pairs of YANG asthenia disease animals
Take mice 70, male and female half and half are randomly divided into 7 groups, 10 per group, respectively YANG asthenia disease model group, embodiment 1～
4 groups and 1,2 groups of comparative example, inject intramuscular injection hydrocortisone 25mg/kg/d, continuous gavage 20d, daily 20ml, YANG asthenia disease model
Group gavage normal saline, embodiment and the corresponding Maca health wine of comparative example group gavage；10 same method breeding observings are separately taken, is made
For Normal group.Mice is administered once a day each group, totally 7 days, and last dose records the swimming of each group mice low temperature and deposits after 1 hour
Live time (10 DEG C of water temperature, depth of water 50cm, wide 50cm, swimming in long 120cm swimming groove) and autonomic activitieses number (in 10min), examination
Test and the results are shown in Table 6.
The impact (X ± SD) that 6 Maca health wine of the present invention of table is swum to YANG asthenia disease animal low temperature
| Group | Low temperature swimming time (min) | Autonomic activitieses number (min) |
| Normal group | 9.7±1.1 | 19.3±1.4 |
| Castration matched group | 7.1±0.8 | 8.0±0.4 |
| Embodiment 1 | 17.2±1.6*# | 25.8±1.8*# |
| Embodiment 2 | 16.8±1.4*# | 25.3±1.5*# |
| Embodiment 3 | 17.1±1.2*# | 25.6±1.6*# |
| Embodiment 4 | 18.6±1.8*# | 26.2±1.9*# |
| Comparative example 1 | 15.3±1.5*# | 22.5±1.2*# |
| Comparative example 2 | 14.2±1.1*# | 21.4±1.9*# |
Note：Compare * p ＜ 0.01 with Normal group, compare #p ＜ 0.05 with YANG asthenia disease group.
As a result show：Heavy dose of hydrocortisone can cause hardy cold, and fatigue proof ability declines, and of the invention
Maca health wine extends the low temperature swimming time of YANG asthenia disease mice, and comparing with YANG asthenia disease group and Normal group has significance
Difference.Maca health wine of the present invention can be remarkably reinforced the autonomic activitieses of mice, and comparing with YANG asthenia disease group and Normal group has aobvious
Write sex differernce.
2.3 hepatoprotective efficacy validations
It is by being provided by the Flos puerariae lobatae, Japanese raisintree fruit synergistic combination that are comprised in the health promoting wine that the present invention reduces hepatic injury
Raising liver protective effect realizing.Lepidinm meyenii Walp is studied from comparative example 1,3,4 as the matched group of the embodiment of the present invention for this
The hepatoprotective effect of health promoting wine.
Rat 40 is taken, male and female half and half are randomly divided into 4 groups, 10 per group, respectively embodiment 4 and comparative example 1,3,4,
Continuous medicine-filling 30d, daily 20ml, embodiment and the corresponding Maca health wine of comparative example gavage.30th day, per 30min pair after perfusion
Every rat tailses take blood 0.5ml, determine ethanol in blood concentration, and measurement result is for after perfusion, during 60min, ethanol in blood is dense
Degree highest；Test malonaldehyde (MDA) content, ethanol dehydrogenase (ADH) activity and the super oxygen determined after terminating for 30 days in blood
Compound dismutase (SOD) activity.Result of the test is shown in Table 7.
Impact (X ± SD) of 7 Maca health wine of the present invention of table to Liver Function
Note：Compare * p ＜ 0.01 with comparative example 1.
Result of the test shows, what in Maca health wine of the present invention, Flos puerariae lobatae, Japanese raisintree fruit contained relieve the effect of alcohol, and material can improve rat
After long-term alcohol, in blood, ADH activity ethanol dehydrogenase (ADH) activity and superoxide dismutase (SOD) are active, accelerating alcohol
Catabolism speed, reduce ethanol in blood content and mesostate acetaldehyde accumulation time in vivo, so as to reduce third
The accumulation of dialdehyde (MDA), plays a part of to reduce alcoholism liver function protecting.Hepatic tissue HE coloration results show that Lepidinm meyenii Walp of the present invention is protected
Hepatic cell fattydegeneration after what Flos puerariae lobatae, Japanese raisintree fruit contained in strong wine relieve the effect of alcohol material can reduce rat long-term alcohol, hepatic necrosis,
The liver dysfunction phenomenon that fatty liver etc. causes occurs, and plays liver protection effect.
Results of pharmacodynamic test shows：Maca health wine of the present invention has raising castrated rats penis to the emerging of outside stimuluss
Putting forth energy property, shortens the preclinical effect of erection.There are increase seminal fluid capsule, prostate, foreskin to kidney deficiency animal (castrated rats)
The effect of gland, uterus weight, this and Maca health wine kidney invigorating and YANG supporting of the present invention, the effect of emerging positive Conclusion Decreasing match.For
Yang deficiency animal (hydrocortisone mice) has strengthens cold resistant ability, extends low temperature swimming time, strengthens autonomic activitieses ability
Effect.The catabolism speed of what Flos puerariae lobatae, Japanese raisintree fruit contained in Maca health wine of the present invention relieve the effect of alcohol material energy accelerating alcohol, drop
Low ethanol in blood content and mesostate acetaldehyde accumulation time in vivo, reduces hepatocyte fat after rat long-term alcohol
The liver dysfunction phenomenon that degeneration, hepatic necrosis, fatty liver etc. cause occurs, and playing reduces the work of alcoholism liver function protecting
With.These effects are superior to change the effect of health promoting wine after formula by comparative example simultaneously, show the medicinal liquor prescription and ratio of the present invention
Example is optimal, energy yin yang complementarity, adjusts internal equilibrium between yin and yang, and reinforce the kidney hepatoprotective, causes sub-health state to have substantially insufficiency of kidney-YANG
Curative effect.
3rd, clinical research
1st, try out test
The Maca health wine Jing clinic insufficiency of kidney-YANG patient of kidney invigorating and YANG supporting of the present invention has taken obvious curative effects, and middle Jing faces altogether
Bed 200 (140 people of male, 60 people of women) insufficiency of kidney-YANG patients take, continuously take 2-3 days, and 100% patient feels the intestines and stomach more
Refreshed, appetite strengthens；The patient for continuously taking 7-15 days 98% feels to refresh oneself, energetic；3 months are taken continuously, 95%
Renal function of patients reaches the disappearance of the symptoms such as the level of normal person, soreness of the waist and knees, aversion to cold and cold limbs, sexual impotence, premature ejaculation, seminal emission, sexual function
Recover normal, drug withdrawal does not rebound.Jing 20 impotence patients of clinic are taken, and continuously take 3 months, and 9 patient's sperm quantities increase
35%-45%；Jing 18 cold sperm patients of clinic take, and the patient of 7-15 days 98% feels that cold sperm phenomenon is alleviated, in 2-3 month,
97% patient occurs without cold sperm phenomenon.Due in Maca health wine its dispensing of kidney invigorating and YANG supporting of the present invention containing Flos puerariae lobatae,
Japanese raisintree fruit, when health promoting wine of the present invention is drunk, can shift to an earlier date and form protecting film in liver, stomach, play a part of liver-protecting and stomach-nourishing, accelerate
Urination, alleviates malaise symptoms of drinking, even if drunk also quickly can wake up or the state that refreshes, therefore the daily dosage of patient can
With the dosage higher than common medicated wine on market.
2nd, typical case
(1) Lee, man, 50 years old, people from Xianning.Live in separate places and suppress sexual life because doing manual work outside all the year round, after return to one's home village development just
Phase does not restrain sexual life causes sexual life frequently, gradually not hard to erection, powerless having sexual intercourse more than 2 years.Jing tcm diagnosis are：Kidney yang
It is empty.Also the supporing yang medicine of various kidney tonifying, health food etc. were once taken and was showed no curative effect.Weak, the waist soreness of existing dizziness, is slept less
Dreaminess, meets labor then palpitation and short breath, shallow complexion, inappetence.Jing takes Maca health wine of the present invention 3 days, and appetite is strengthened, sleep
Quality improves；Energetic after 1 month, complexion shows red, and from head to foot energetically, sexual function makes moderate progress；After 3 months, sexual impotence symptom disappears
Lose, sexual function recovers normal, and feel that resistance is significantly improved, indefatigability.
(2) Zhang, man, 32 years old, people from Wuhan.2 years after marriage, the normal night sweat of Jing, soreness of the waist and knees, sexual impotence, life quality is always
Undesirable, body void is weak, listless, to never fertilization later.Jing tcm diagnosis are：Insufficiency of kidney-YANG.Also once took excessive
The supporing yang medicine of kidney tonifying, health food etc. is planted, equal effect on driving birds is not good, used time are effective, and the recovery for stopping, erection be not hard.Jing takes
After Maca health wine of the present invention 5 days, libido slightly strengthens, and sexual impotence shape slightly improves；After being used in conjunction 2 months, all sexual impotence, tired nothing
The diseases such as power, soreness of the waist and knees all disappear, and erection is hard, and sexual life recovers normal, and follow-up after a year is not recurred, and its child
It is fast to be born.
(3) it is neat certain, female, 42 years old.Often there are following symptoms in Jing in recent years：Sore waist and aching in the waist and the back, shallow complexion, inappetence,
Tinnitus, stagger, it is forgetful sleep less, easily tired, little drip of having a surplus after an action of the bowels, nocturia increases, climacteric indifferent to sexual behavior carries
Before.Jing tcm diagnosis are：Insufficiency of kidney-YANG.Jing drinks the tonic wine of the present invention, and daily 50ml is conscious energetic after 3 months, is difficult tired
Labor, above-mentioned symptom disappear.
In sum, Maca health wine of the invention has obvious temperature compensation Liver and kidney, tonifying YANG controlling nocturnal emission with astringent drugs, enhancing immunity, alleviation
Tired the effects such as, for insufficiency of kidney-YANG patient, especially impotence patient is evident in efficacy.Change arbitrary prescription of the invention or its ratio, medicine
Physical therapy effect and mouthfeel do not have the present invention good.
Although an embodiment of the present invention has been shown and described, for the ordinary skill in the art, can be with
Understanding can carry out various changes, modification, replacement to these embodiments without departing from the principles and spirit of the present invention
And modification, the scope of the present invention be defined by the appended.
Claims (6)
1. a kind of Maca health wine of kidney invigorating and YANG supporting, it is characterised in that by weight, its raw material include 20～40 parts of Lepidinm meyenii Walp,
10～25 parts of Herba Cistanches, 10～15 parts of Radix Morindae Officinaliss, 12～20 parts of Fructus Lycii, 10～15 parts of Rhizoma Polygonati, 10～20 parts of the Cortex Eucommiae, Fructus Rubi
10～20 parts, 12～20 parts of Fructus Rosae Laevigatae, 10～20 parts of leek seed, 5～20 parts of Flos puerariae lobatae, 5～20 parts of Japanese raisintree fruit, 8～15 parts of Radix Glycyrrhizae.
2. the Maca health wine of a kind of kidney invigorating and YANG supporting according to claim 1, it is characterised in that by weight, which is former
Material include 30 parts of Lepidinm meyenii Walp, 20 parts of Herba Cistanches, 15 parts of Radix Morindae Officinaliss, 15 parts of Fructus Lycii, 12 parts of Rhizoma Polygonati, 15 parts of the Cortex Eucommiae, 10 parts of Fructus Rubi,
15 parts of Fructus Rosae Laevigatae, 15 parts of leek seed, 8 parts of Flos puerariae lobatae, 8 parts of Japanese raisintree fruit, 10 parts of Radix Glycyrrhizae.
3. the preparation method of the Maca health wine of a kind of kidney invigorating and YANG supporting described in claim 1 or 2, it is characterised in that include as
Lower step：A, by Lepidinm meyenii Walp, Herba Cistanches, Radix Morindae Officinaliss, Rhizoma Polygonati, the Cortex Eucommiae, Radix Glycyrrhizae chopping, be cut into 0.2～0.5cm of cross-sectional area2It is broken
Piece, is dried with 30 DEG C～60 DEG C of temperature after cleaning；By Fructus Lycii, Fructus Rubi, Fructus Rosae Laevigatae, leek seed, Flos puerariae lobatae, Japanese raisintree fruit cleaning
After dry；B, the component that step A is obtained is put into into wine vat, according to 1：5～1：10 ratio adds Chinese liquor, and wine vat is sealed, and soaks
Bubble 30～60 days, daily inverted engine 1～3 time in immersion process；After C, soak time terminate, wine vat is opened, filtration obtains final product health promoting wine.
4. the preparation method of the Maca health wine of a kind of kidney invigorating and YANG supporting according to claim 3, it is characterised in that described white
The alcoholic strength of wine is 42～70 °.
5. the preparation method of the Maca health wine of a kind of kidney invigorating and YANG supporting according to claim 4, it is characterised in that described white
The alcoholic strength of wine is 65 °.
6. a kind of preparation method of the Maca health wine of kidney invigorating and YANG supporting according to claim 3, it is characterised in that the guarantor
The number of degrees of strong wine are 35～62 °.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN107841432A (en) * | 2017-12-12 | 2018-03-27 | 合肥市绿之林农业开发有限公司 | A kind of okra health liquor of tonifying kidney and strengthening yang and preparation method thereof |
| CN110859918A (en) * | 2019-12-09 | 2020-03-06 | 华中科技大学同济医学院附属协和医院 | Medicine and food homologous prescription for treating kidney-yang deficiency and preparation method thereof |
| CN115176995A (en) * | 2022-05-12 | 2022-10-14 | 常州芭瑞雅生物科技有限公司 | Male health-care composition and preparation method thereof |
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| CN102260623A (en) * | 2011-07-04 | 2011-11-30 | 天津鼎亚生物工程科技有限公司 | Health care wine capable of dispelling alcohol effect, eliminating dampness and protecting liver and preparation method thereof |
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| CN105031238A (en) * | 2015-07-10 | 2015-11-11 | 象州县百丈酒厂 | Maca traditional Chinese medicine health wine and brewing method thereof |
| CN105623983A (en) * | 2014-11-07 | 2016-06-01 | 安徽中医药大学 | Energy-invigorating liver-nourishing eyesight-improving wine and preparation method thereof |
| CN105950395A (en) * | 2016-05-31 | 2016-09-21 | 亳州市永博保健食品有限公司 | Kidney-invigorating and Yang-strengthening traditional Chinese medicine health care wine |
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| CN102260623A (en) * | 2011-07-04 | 2011-11-30 | 天津鼎亚生物工程科技有限公司 | Health care wine capable of dispelling alcohol effect, eliminating dampness and protecting liver and preparation method thereof |
| CN102827750A (en) * | 2012-09-21 | 2012-12-19 | 李光 | Maca health care liquor for improving organism immunity and sexuality |
| CN105623983A (en) * | 2014-11-07 | 2016-06-01 | 安徽中医药大学 | Energy-invigorating liver-nourishing eyesight-improving wine and preparation method thereof |
| CN105031238A (en) * | 2015-07-10 | 2015-11-11 | 象州县百丈酒厂 | Maca traditional Chinese medicine health wine and brewing method thereof |
| CN105950395A (en) * | 2016-05-31 | 2016-09-21 | 亳州市永博保健食品有限公司 | Kidney-invigorating and Yang-strengthening traditional Chinese medicine health care wine |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN107841432A (en) * | 2017-12-12 | 2018-03-27 | 合肥市绿之林农业开发有限公司 | A kind of okra health liquor of tonifying kidney and strengthening yang and preparation method thereof |
| CN110859918A (en) * | 2019-12-09 | 2020-03-06 | 华中科技大学同济医学院附属协和医院 | Medicine and food homologous prescription for treating kidney-yang deficiency and preparation method thereof |
| CN115176995A (en) * | 2022-05-12 | 2022-10-14 | 常州芭瑞雅生物科技有限公司 | Male health-care composition and preparation method thereof |
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