CN102827750A - Maca health care liquor for improving organism immunity and sexuality - Google Patents

Maca health care liquor for improving organism immunity and sexuality Download PDF

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Publication number
CN102827750A
CN102827750A CN2012103522610A CN201210352261A CN102827750A CN 102827750 A CN102827750 A CN 102827750A CN 2012103522610 A CN2012103522610 A CN 2012103522610A CN 201210352261 A CN201210352261 A CN 201210352261A CN 102827750 A CN102827750 A CN 102827750A
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parts
liquor
agate coffee
health care
maca
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陈曦
李光
李宜航
李学兰
马小军
宋美芳
赵俊凌
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李光
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Abstract

The invention discloses a maca health care liquor for improving organism immunity and sexuality. The formula of the maca health care liquor comprises the following ingredients in parts by weight: 5-20 parts of maca, 2-6 parts of ginseng, 4-8 parts of wolfberry, 4-8 parts of herba epimedii, 1-5 parts of cornu cervi pantotrichum, 5-10 parts of astragalus, 5-8 parts of polygonatum, 3-10 parts of cistanche deserticola and 100-200 parts of white spirit, wherein the white spirit is a grain brewed wine, and has the alcohol content of 48-68%, and the medicinal materials are grounded into fine powder, then cooked, soaked, percolated and subjected to other extraction methods to produce the maca health care liquor. The formula is compounded under the guidance of traditional Chinese medicine theory, and on the basis of maca, drugs for tonifying qi and replenishing blood, nourishing yin and tonifying yang are added, so that the maca health care liquor has a mellow taste and an obvious effect and is suitable for the medium-aged and aged patients suffering from diabetes.

Description

A kind of agate coffee health promoting wine with enhance immunity power and property vigor
Technical field
The present invention relates to field of health care products, particularly a kind of agate coffee health promoting wine with enhance immunity power and property vigor.
Background technology
(MACA, Latin is by name for the agate coffee Lepidium meyenii Walp) originate from the Peru highlands, be used for strengthening body traditionally, improve fertility; Sexual function improving etc., the South America locals uses as beverage through frying or press into juice, but modern study shows; The main pharmacodynamics material is fat-soluble agate coffee alkaloids in the agate coffee, and conventional eating method can not good absorption agate coffee alkaloids, though also have the agate coffee is immersed in the Maca wine that can obtain to have tonic effect in the wine; But enrich tori seed oil glycoside material owing to contain in the agate coffee; It is relatively poor to soak the back mouthfeel separately, can not let everyone accept, and adds honey etc. for improving mouthfeel; Again the diabetic subject is produced harm, therefore be necessary to provide that a kind of nourishing function is definite, mouthfeel better, drink conveniently, not sacchariferous agate coffee health promoting wine.
Summary of the invention
The purpose of embodiments of the invention is the defectives to above-mentioned prior art, provides that a kind of nourishing function is definite, mouthfeel is better, drinks agate coffee health promoting wine easily.
For realizing that the embodiment technical scheme that above-mentioned purpose the present invention takes is:
A kind of agate coffee health promoting wine with enhance immunity power and property vigor, its prescription comprises following weight part material:
Agate coffee 5-20 part, genseng 2-6 part, matrimony vine 4-8 part, Herba Epimedii 4-8 part, pilose antler 1-5 part, Radix Astragali 5-10 part, sealwort 5-8 part, Herba Cistanches 3-10 part, liquor 100-200 part, liquor is the grain fermented wine, the alcohol number of degrees are the 48-68 degree.
Most preferably scheme of the present invention is: 10 parts of agate coffees, 4 parts of gensengs, 5 parts of matrimony vines, 6 parts of Herba Epimedii, 3 parts in pilose antler, 8 parts of the Radixs Astragali, 7 parts of sealworts, 6 parts of Herba Cistanchess, 200 parts of liquor, and liquor is the grain fermented wine, the alcohol number of degrees are 55 degree.
The beneficial effect that technical scheme provided by the invention is brought is:
1, the agate coffee is the long-term edible foods of the Peru area people, the good and clear efficacy of edible safety, and the U.S. FDA approved is produced as healthy food material.Though because tori seed oil glycoside material exists in the agate coffee, taste is special, can not let everyone accept, through reducing the influence of tori seed oil glycoside material behind the compatibility, mouthfeel is better, and can strengthen drug effect.
2, this prescription carries out prescription under traditional Chinese medical theory instructs, and on the basis of agate coffee, the increase tonifying Qi is enriched blood, the nourishing and strengthening vital medicine promptly can improve mouthfeel and can strengthen drug effect again.
3, this prescription improves mouthfeel through the character of medicinal material own, and emphasis is a polyose composition in the medicinal material, does not add any use auxiliary material, and the elderly and the diabetic subject that are fit to hypoimmunity take, and the immunizing power that can be used in the diabetic therapy process improves.
Pharmacological mechanism of the present invention is:
Genseng ( Panax ginseng) the Araliaceae perennial herb, famous Chinese medicine, Shennong's Herbal is classified as top grade.Wild survivor claims the mountain ginseng; The grower claims garden ginsent.Main product is adopted root autumn in northeast.Because of the working method difference has sun-cured suncured ginseng, sugared ginseng (white ginseng), red ginseng, ginseng must be other.Originate in the Korea person, be called Korean ginseng or Radix Ginseng.Genseng contains ginsengsu, panacene, ginsenoside, panaxynol, lipid acid, volatile oil, VITAMINs, enzyme etc.Genseng has the strengthening by means of tonics effect, can reinforce vital energy, the intelligence development of allaying excitement, invigorating the spleen, nourish blood, beneficial gas, promotes the production of body fluid.Genseng is all influential with inhibition to the excitement of cns, can strengthen the intensity and the handiness of pallium excited process, improves work capacity, reduces fatigue, improves appetite and sleep, and enhancing body is disease-resistant
Ability; Excited hypophysis-interrenal system can improve the resistibility that body stimulates severe environment; Have synergy with pancreas islet, the ability lowering blood glucose can promote men and women's sexual gland function; Low dose makes palpitating speed, and myocardial contraction strengthens, and the cardiotonic glycoside effect is seemingly arranged; The adjustable cholesterol metabolic suppresses the generation of hypercholesterolemia; Can improve digestion and absorption function, improve a poor appetite, make hematopoietic function vigorous, improve leukocytic phagocytic activity, promote protein synthesis.Genseng often due to illness human organism's functional state difference be biphasic effect, so genseng is to have the typical case's representative that adapts to the former state effect in the Chinese medicine.
Herba Epimedii ( Epimedium grandiflorum) as traditional kidney invigorating and YANG supporting Chinese medicine, because of its unique composition and significant biological activity enjoy attention.China is the distribution center of barrenwort, has reported 27 kinds and 4 mutation so far.Herba Epimedii mainly contains the substituted flavonoid compound of isopentene group, like various icariines etc.In addition, lignan class, phenol glucoside, ionone class, sesquiterpenoids and phenylethyl alcohol glucoside etc. are still arranged.Herba Epimedii can promote albumen synthetic, improves nephrotic's life quality; Can promote osteogenesis; Can directly expand cardiovascular and cerebrovascular, increase the blood flow of heart and brain; Can strengthen the body cell immunologic function, the tool immunocompetence can be used for the sick assisting therapy of AIDS; In addition, Herba Epimedii also has androgen-like action.
Pilose antler ( Cornu Cervi Pantotrichum) be traditional Yang invigorating medicine, the prescription that successive dynasties interpolation pilose antler is treated andropathy all has a lot, and doing experimentation on animals with the extracting solution of pilose antler also has better curative effect; The pilose antler extracting solution can strengthen the immunoreation of delaying property; Increase the quantity of rosette cell in the splenocyte, the influence of pair cell lectin and erythrocyte hemolysin is remarkable, in addition; Antler liquid can also increase the weight of immune organs such as spleen and thymus gland; This all explains Cornu Cervi Pantotrichum extract to strengthening the function of cellular immunization, promotion humoral immunization, and simultaneously, experiment proof pilose antler polysaccharides also has same effect.The abundant nutrition that contains in the pilose antler can also improve the work capacity of body; Alleviate the fatigue of muscle; Pantocrine can increase the mouse swimming time; The aqueous extract of pilose antler and alcohol extract all can prolong the mouse swimming time, and the pilose antler decoction can significantly improve the hypoxia-bearing capability of mouse, have the obvious anti-fatigue effect.
Herba Cistanches ( Herbal Cistanche), the beginning is stated from Shennong's Herbal, classifies as top gradely, and LI Shi-Zhen is said: " this thing is mended and not high, so have calmly ".Herba Cistanches flavor is sweet, salty, warm in nature, the function that have kidney-replenishing, benefiting essence-blood, relaxes bowel, and the use in existing more than 2,000 year is historical in China.Cistanche glycosides (being mainly benzyl carbinol glycosides) is an activeconstituents main in the Herba Cistanches; Have multiple functions such as establishing-Yang, anti-oxidant, memory; The Herba Cistanches polysaccharide can also prolong the hypoxia endurance time of mouse aging, and Ultrastructural regressions such as mouse lung cell mitochondrial, lamellar body delay senility.Herba Cistanches decocting liquid can significantly improve the phagocytic percentage and the phagocytic index of scavenger cell, the external mouse thymus lymphopoiesis that promotes of the Herba Cistanches polysaccharide fraction of the definite molecular weight of tool.
The Radix Astragali (Milkvetch Root) has the function of invigorating QI to consolidate the body surface resistance, and it contains multiple biologically active substances such as polysaccharide, protein, vegeto-alkali, amino acid, flavonoid, glycoside, trace element, wherein the immunocompetence of polysaccharide is particularly outstanding.It both can directly influence the metabolism of intracellular matter, can induce body cell to produce relevant humoral factor again, thereby further influence other cell activity; But both non-specific immunity of enhancing body; Also can strengthen the immunologic function of normal body, again the unusual immunologic function of adjustable body.Astragalus polysaccharides can improve lymphocytic transformation efficiency and body to antigenic immunne response ability, strengthens the phagocytic activity of scavenger cell, and various medicines and different immunologic function under stress pattern are reduced, and all has significant immuno-potentiation.
Sealwort (P.sibiricumRedoute) property is flat, flavor is sweet; Return spleen, lung, kidney channel; Have functions such as boosting qi and nourishing yin, invigorating the spleen, moistening lung, kidney-nourishing; Be used for weakness of the spleen and the stomach, fatigue and asthenia, dry food less, deficiency syndrome of the lung cough caused by dryness, asthenia of essence and blood, interior heat quenches one's thirst.In recent years, people deepen continuously to the Polygonatum Study on plants, from this platymiscium, have separated obtaining a lot of chemical ingredientss: carbohydrate, steroid saponin, flavonoid etc.Wherein steroidal saponin is to be master's immunostimulant to strengthen humoral immunization and phagocytic function in the sealwort.Sibiricoside POD-III can be worked in coordination with the Asia and accommodated canavalin(e) (concanavalin, ACon A) and the LPS of dose,optimum (lipopplysaccharide LPS), has promoter action and anti-microbial effect etc. to lymphocyte transformation when lower concentration.IL-2 content in thymus gland, index and spleen index and the serum of coarse solomon's seal polysaccharide ability elevation model rat can also improve the thymus index of rat, has the effect of enhance immunity power.
Matrimony vine (Lycium chinense) is tonic important in our traditional medicine, the Shennong's Herbal record " matrimony vine, a Chinese holly is own, and a sheep breast is obeyed for a long time, hard muscles and bones, it is not old to make light of one's life by commiting suicide ", classified as top grade.Wolfberry fruit property is flat, and it is sweet to distinguish the flavor of, have nourishing liver and kidney, replenishing vital essence to improve eyesight, the effect that improves the health, wolfberry fruit can be taken for a long time, and is nontoxic, have no side effect.LBP (LBP) is the main bioactive ingredients of wolfberry fruit, is made up of six kinds of monose such as pectinose, glucose, semi-lactosi, seminose, rhamnosyl and wood sugars, contains various trace elements and amino acid, and its major ingredient is protein-polysaccharide-glycopeptide.This polysaccharide composition is its basis of " strengthening the body resistance to consolidate the constitution ".Modern age, pharmacological research showed, LBP has immunomodulatory, antitumor, anti-ageing, reducing blood-fat, hypoglycemic, the effect of protecting liver, anti-ray, antifatigue and Green Tea Extract.
This health promoting wine pharmacodynamic experiment research:
One, raising property vigor functional experiment
1, experiment material
1.1 medicine: agate coffee health promoting wine, planting institute's Yunnan branch research and development prepared in laboratory by Chinese medical courses in general institute medicine provides, and before the experiment health promoting wine is carried out concentrating under reduced pressure, with alcohol recovery in the health promoting wine, obtains suspension and experimentizes.NANBAO JIAONANG, Lik-Sang pharmaceutical factory, Tianjin produces.
1.2 animal: U.S.'s wild-type drosophila melanogaster.
1.3 fruit bat substratum: Semen Maydis powder 10g, white sugar 13.5g, agar 1.5g, propionic acid 1ml, dried yeast powder 1.2g add water to 100g.Substratum preparation back adds medicine, makes content of dispersion be respectively 0.5% agate coffee health promoting wine, 1% agate coffee health promoting wine and 0.5% NANBAO JIAONANG.
1.4 culture condition: get the pastille substratum of adorning 1.5 ± 0.2cm thickness in 3 * 8cm culture tube.23 ± 1 ℃ of culture temperature, relative humidity 60%~80%, natural lighting time.Changed a subculture in per 3 days.
2, experimental technique-fruit bat property vigor functional experiment
Collect the fruit bat adult that sprouts wings in the 8h, with supporting by the male and female branch behind the etherization.Male fly random packet, every group 10 pipe, 1 of every pipe.Control group is used basic medium, and experimental group gives the agate coffee health promoting wine substratum of different concns, and positive group gives the NANBAO JIAONANG substratum, feeds 15d continuously, last carrying out property of 1d vitality test.
After the experiment beginning, put in the male fly pipe record mating latent period (closing pipe), the number of times of fluttering its wings up and down (male fly chases the action of fluttering its wings up and down of female fly before the mating), mating time with the ratio of 3:1 to the time that begins mating with the virgin fly in 3~4 day age.Behind 1h, female fly is told in anesthesia, and pipe is placed in addition.
3, experimental result
Table 1. agate coffee health promoting wine is to the influence of fruit bat property vigor
Group Mating latent period (min) The number of times of fluttering its wings up and down Mating time (min)
Control group 34.2±16.1 14.6±6.5 13.1±10.6
Agate coffee (0.5%) 18.9±4.5 ˉ 15.8±5.1 28.4±5.9 ˉ
Agate coffee (1%) 16.3±4.5 ˉ 16.9±4.3 29.1±3.3 ˉ
Treasure for Man (0.5%) 25.7±4.9 14.7±4.1 22.7±4.7 ˉ
" -" represent to compare P ﹤ 0.05. with control group
The result shows, mating latent period that two dose groups of agate coffee health promoting wine all can significantly shorten fruit bat with prolong mating time, but the fruit bat number of times of fluttering its wings up and down is not had obvious influence, research prompting agate coffee health promoting wine is to the property vigor effect of improving of drosophila melanogaster.
Two, raise immunity experiment
1. experiment material
1.1 experiment medicine: agate coffee health promoting wine; Planting institute's Yunnan branch research and development prepared in laboratory by Chinese medical courses in general institute medicine provides; Before the experiment health promoting wine being carried out concentrating under reduced pressure reclaims alcohol in the health promoting wine; Use Ebullioscope to measure ethanol concn, the agate coffee health promoting wine that obtains alcoholic strength and be zero suspension prepares liquid and experimentizes.China is with the ganoderan capsule, and Luoyang China is with biotechnology ltd.
1.2 laboratory animal: ICR mouse, SPF level, male and female half and half, army Ke Yuan institute of lab animals, credit number: SCXK-(army) 2007-004.
1.3 reagent and instrument
2, experimental technique
2.1 laboratory animal divides into groups
Mouse is divided into control group, low dose group, middle dose groups, high dose group and positive group, 30 every group by body weight at random after adapting to 3d under the experimental situation.Control group gives saline water; 3 dose groups give agate coffee health promoting wine respectively and prepare liquid 130,260,390mg/kg/d, and positive group gives China with ganoderan capsule solution 530mg/kg/d, and each organizes continuous gastric infusion 30d; During the administration, mouse freely ingests and drinks water.After finishing, administration carries out the and the following experiment.
2.2 foot is opened up the swelling experiment: inject mouse peritoneal with SRBC, inducing mouse produces delayed hypersensitivity.After 6 days, as the injection of toes once more SRBC, delayed hypersensitivity appears in the visible position of attacking.Its injection SRBC after 24 hours with the injection before toes thickness difference reflects the power of delayed hypersensitivity.
2.3 carbon clearance experiment: 1h after the administration of mouse last, by tail vein injection 16mg/mL india ink, whenever at a distance from 3 minutes, get blood then from eye socket, continuous 5 times, take out spleen and thymus gland and weigh, the ratio of statistics and body weight, each compares between organizing.Statistics is engulfed speed and activate the phagocytic capacity, and liver, spleen index.
2.4 lymphocyte transformation experiment: use RPMI-1640 preparation 4 * 10 6/ mL mouse boosting cell suspension adds 100 μ L splenocyte suspensions and 100 μ L nutrient solutions in 96 orifice plates, positive control uses 5 μ g/mL ConA, and given the test agent adds agate coffee suspension, 5%CO according to volume ratio 0.5%, 1% and 2% 2, 37 ℃ of cultivations.Cultivate and finish preceding 4h, add MTT solution, continue then to cultivate and read the A value with ELIASA 570nm.
2.5 hemolysis barren spot experiment: mouse peritoneal injection 5%SRBC 0.2mL sensitization, with the blank of doing of sensitization not.Use the SRBC of GPS and volume ratio 10:1 to mix, leave standstill 4 ℃ of 30min, the centrifugal 10min of 2000r/min gets supernatant as complement then.Title 1.4g agarose joins in the 100mLGey liquid and boils, and injects diameter 9mm plate then, and is subsequent use in 37 ℃ of incubators.The preparation top-layer agar adds SRBC and splenocyte suspension, then top-layer agar is poured on the agar of 37 ℃ of preheatings, puts incubator and cultivates 2h.The GPS 0.1mL that in plate, adds 10 times of dilutions, incubation 40min takes out room temperature and places 1h, and refrigerator spends the night for 4 ℃, and the decomplementation that inclines next day adds 0.25% LUTARALDEHYDE and fixes, and counts plaque then.
 
3, experimental result
3.1 foot is opened up the swelling experiment
Table 1. agate coffee health promoting wine to mouse foot open up swelling influence (
Figure 2012103522610100002DEST_PATH_IMAGE001
Figure 487423DEST_PATH_IMAGE002
s, n=10)
Group Dosage (mg/kg) Time/mm
Control group 0.44±0.13
Agate coffee low dose group 130 0.52±0.16
Dose groups in the agate coffee 260 0.57±0.15
Agate coffee high dose group 390 0.66±0.27
Compare with control group P<0.05
High dose group obviously increase the weight of the foot open up the swelling degree, relatively improved 50% with control group, difference have the significance meaning ( P<0.05).
3.2 carbon clearance experimental result
Table 2. agate coffee health promoting wine to the influence of mouse phagocytic rate and phagocytic index (
Figure 156302DEST_PATH_IMAGE001
Figure 336617DEST_PATH_IMAGE002
s, n=10)
Group Dosage (mg/kg) Phagocytic rate/% Phagocytic index
Control group 28.8±8.2 0.57±0.17
Agate coffee low dose group 130 34.7±9.4 0.75±0.21
Dose groups in the agate coffee 260 37.6±11.3 0.78±0.25
Agate coffee high dose group 390 41.7±7.9 0.83±0.12
Compare with control group P<0.05
With control group relatively, agate coffee high dose group phagocytic rate and phagocytic index improve 44.8% and 45.6% respectively, difference have the significance meaning ( P<0.05).
3.3 lymphocyte proliferation assay
Table 3. agate coffee health promoting wine to the influence of mice spleen lymphocytes proliferation (
Figure 90946DEST_PATH_IMAGE001
Figure 765641DEST_PATH_IMAGE002
s, n=10)
Group Dosage (mg/kg) OD
Control group 0.059±0.026
Agate coffee low dose group 130 0.078±0.033
Dose groups in the agate coffee 260 0.086±0.034
Agate coffee high dose group 390 0.107±0.042
Compare with control group P<0.05
Agate coffee high dose group can significantly improve lymphopoiesis ability 81%, difference have the significance meaning ( P<0.05).
3.4 hemolysis barren spot experiment
Table 4. agate coffee health promoting wine to the influence of mice spleen lymphocytes proliferation (
Figure 289026DEST_PATH_IMAGE001
Figure 407286DEST_PATH_IMAGE002
s, n=10)
Group Dosage (mg/kg) PFC number/10 6Splenocyte
Control group 43.3±10.7
Agate coffee low dose group 130 56.4±23.1
Dose groups in the agate coffee 260 72.9±17.5 ﹡﹡
Agate coffee high dose group 390 97.8±32.1 ﹡﹡
Compare with control group P<0.05, ﹡ ﹡ P<0.01
Dosage and high dosage all can improve the average 68% and 126% that per 1,000,000 splenocytes contain the plaque cell in the agate coffee, difference have the significance meaning ( P<0.01).
Embodiment
For making the object of the invention, technical scheme and advantage more clear, below specific embodiments of the invention do further detailed description.
Embodiment 1
5 parts of agate coffees, 2 parts of gensengs, 4 parts of matrimony vines, 4 parts of Herba Epimedii, 1 part in pilose antler, 5 parts of the Radixs Astragali, 5 parts of sealworts, 3 parts of Herba Cistanchess, 100 parts of liquor, liquor is the grain fermented wine, the alcohol number of degrees are 48 degree.At first with above-mentioned medicinal material powder to meal, add liquor, soaked 24 hours, keep slight boiling condition, boiling 24 hours cools to room temperature, 8 layers of filtered through gauze are got filtrating sedimentation 7 days under 4-10 ℃ of environment, filter, and bottle, and obtain finished product.
Embodiment 2
5 parts of agate coffees, 2 parts of gensengs, 4 parts of matrimony vines, 4 parts of Herba Epimedii, 1 part in pilose antler, 5 parts of the Radixs Astragali, 5 parts of sealworts, 3 parts of Herba Cistanchess, 100 parts of liquor, liquor is the grain fermented wine, the alcohol number of degrees are 48 degree.At first with above-mentioned medicinal material powder to meal, add liquor, soaks 8 layers of filtered through gauze after 15 days, get filtrating sedimentation 7 days under 4-10 ℃ of environment, filter, bottle, obtain finished product.
Embodiment 3
5 parts of agate coffees, 2 parts of gensengs, 4 parts of matrimony vines, 4 parts of Herba Epimedii, 1 part in pilose antler, 5 parts of the Radixs Astragali, 5 parts of sealworts, 3 parts of Herba Cistanchess, 100 parts of liquor, liquor is the grain fermented wine, the alcohol number of degrees are 48 degree.At first with above-mentioned medicinal material powder to meal, add a small amount of liquor and carried out swelling 24 hours, the medicinal material diacolation of packing into is thought highly of, add liquor, carry out diacolation with 1mL/min speed, get percolate sedimentation 7 days under 4-10 ℃ of environment, filter, bottling obtains finished product.
Embodiment 4
20 parts of agate coffees, 6 parts of gensengs, 8 parts of matrimony vines, 8 parts of Herba Epimedii, 5 parts in pilose antler, 10 parts of the Radixs Astragali, 8 parts of sealworts, 10 parts of Herba Cistanchess, 200 parts of liquor, liquor is the grain fermented wine, the alcohol number of degrees are 48 degree.At first with above-mentioned medicinal material powder to meal, add liquor, soaked 24 hours, keep slight boiling condition, boiling 24 hours cools to room temperature, 8 layers of filtered through gauze are got filtrating sedimentation 7 days under 4-10 ℃ of environment, filter, and bottle, and obtain finished product.
Embodiment 5
20 parts of agate coffees, 6 parts of gensengs, 8 parts of matrimony vines, 8 parts of Herba Epimedii, 5 parts in pilose antler, 10 parts of the Radixs Astragali, 8 parts of sealworts, 10 parts of Herba Cistanchess, 200 parts of liquor, liquor is the grain fermented wine, the alcohol number of degrees are 48 degree.At first with above-mentioned medicinal material powder to meal, add liquor, soaks 8 layers of filtered through gauze after 15 days, get filtrating sedimentation 7 days under 4-10 ℃ of environment, filter, bottle, obtain finished product.
Embodiment 6
20 parts of agate coffees, 6 parts of gensengs, 8 parts of matrimony vines, 8 parts of Herba Epimedii, 5 parts in pilose antler, 10 parts of the Radixs Astragali, 8 parts of sealworts, 10 parts of Herba Cistanchess, 200 parts of liquor, liquor is the grain fermented wine, the alcohol number of degrees are 48 degree.At first with above-mentioned medicinal material powder to meal, add a small amount of liquor and carried out swelling 24 hours, the medicinal material diacolation of packing into is thought highly of, add liquor, carry out diacolation with 1mL/min speed, get percolate sedimentation 7 days under 4-10 ℃ of environment, filter, bottling obtains finished product.
Embodiment 7
10 parts of agate coffees, 4 parts of gensengs, 5 parts of matrimony vines, 6 parts of Herba Epimedii, 3 parts in pilose antler, 8 parts of the Radixs Astragali, 7 parts of sealworts, 6 parts of Herba Cistanchess, 200 parts of liquor, liquor is the grain fermented wine, the alcohol number of degrees are 48 degree.At first with above-mentioned medicinal material powder to meal, add liquor, soaked 24 hours, keep slight boiling condition, boiling 24 hours cools to room temperature, 8 layers of filtered through gauze are got filtrating sedimentation 7 days under 4-10 ℃ of environment, filter, and bottle, and obtain finished product.
Embodiment 8
10 parts of agate coffees, 4 parts of gensengs, 5 parts of matrimony vines, 6 parts of Herba Epimedii, 3 parts in pilose antler, 8 parts of the Radixs Astragali, 7 parts of sealworts, 6 parts of Herba Cistanchess, 200 parts of liquor, liquor is the grain fermented wine, the alcohol number of degrees are 48 degree.At first with above-mentioned medicinal material powder to meal, add liquor, soaks 8 layers of filtered through gauze after 15 days, get filtrating sedimentation 7 days under 4-10 ℃ of environment, filter, bottle, obtain finished product.
Embodiment 9
10 parts of agate coffees, 4 parts of gensengs, 5 parts of matrimony vines, 6 parts of Herba Epimedii, 3 parts in pilose antler, 8 parts of the Radixs Astragali, 7 parts of sealworts, 6 parts of Herba Cistanchess, 200 parts of liquor, liquor is the grain fermented wine, the alcohol number of degrees are 48 degree.At first with above-mentioned medicinal material powder to meal, add a small amount of liquor and carried out swelling 24 hours, the medicinal material diacolation of packing into is thought highly of, add liquor, carry out diacolation with 1mL/min speed, get percolate sedimentation 7 days under 4-10 ℃ of environment, filter, bottling obtains finished product.
The above is merely preferred embodiment of the present invention, and is in order to restriction the present invention, not all within spirit of the present invention and principle, any modification of being done, is equal to replacement, improvement etc., all should be included within protection scope of the present invention.

Claims (3)

1. the agate coffee health promoting wine with enhance immunity power and property vigor is characterized in that being made up of following weight part material: agate coffee 5-20 part, genseng 2-6 part, matrimony vine 4-8 part, Herba Epimedii 4-8 part, pilose antler 1-5 part, Radix Astragali 5-10 part, sealwort 5-8 part, Herba Cistanches 3-10 part, liquor 100-200 part.
2. the agate coffee health promoting wine with enhance immunity power and property vigor as claimed in claim 1 is characterized in that used liquor is the grain fermented wine, and the alcohol number of degrees are the 48-68 degree.
3. the agate coffee health promoting wine with enhance immunity power and property vigor as claimed in claim 1 is characterized in that, above-mentioned medicinal material powder to meal, is made through process for extracting such as boiling, immersion, diacolations.
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CN103289876A (en) * 2013-06-26 2013-09-11 泸州品创科技有限公司 Production method of Maca health wine
CN103393109A (en) * 2013-07-31 2013-11-20 邓青 Magic maca propolis phenformin
CN103393108A (en) * 2013-07-31 2013-11-20 朱晓琳 Maca Chinese yam rejuvenating pellet
CN103468504A (en) * 2013-09-06 2013-12-25 铁岭市西丰御林鹿业集团有限公司 Pilose antler healthcare wine
CN103555537A (en) * 2013-11-25 2014-02-05 张朝峰 Pilous antler healthcare wine and mechanical preparation method thereof
CN103627600A (en) * 2013-11-21 2014-03-12 贵州鑫吾福酒业有限公司 Maca healthcare wine and preparation method thereof
CN103666967A (en) * 2013-12-09 2014-03-26 冯裕夫 Maca wine
CN103923812A (en) * 2014-05-09 2014-07-16 青海伟康生物科技有限公司 Maca wine
CN103981070A (en) * 2014-05-14 2014-08-13 朱义 Maca nutritional health wine
CN104017706A (en) * 2014-06-27 2014-09-03 云南轩健生物科技有限公司 Maca wine
CN104479953A (en) * 2014-11-28 2015-04-01 广西南宁劲能农业科技有限公司 Maca wine
CN104560570A (en) * 2015-01-09 2015-04-29 杨昊军 Maca juice liquor and preparation method thereof
CN104974913A (en) * 2015-08-08 2015-10-14 安国市关汉卿养生酒有限公司 Maca health-preserving wine and preparation method thereof
CN105296300A (en) * 2015-11-11 2016-02-03 王宝珍 Maca and ginseng liquor and production process thereof
CN105695272A (en) * 2015-08-27 2016-06-22 泸州老窖集团养生酒业有限责任公司 Maca compound healthcare wine and production method thereof
CN106318820A (en) * 2015-08-27 2017-01-11 泸州品创科技有限公司 Healthcare wine for relieving physical fatigue and preparing method thereof
CN106350413A (en) * 2016-11-04 2017-01-25 江苏苏中健康产业有限公司 Compound health wine and preparation method thereof
CN106399008A (en) * 2016-05-25 2017-02-15 宁波藏云玛卡生物科技有限公司 Maca and crocus sativus wine and preparation method thereof
CN106511762A (en) * 2016-12-23 2017-03-22 武汉华士特工业生物技术开发有限公司 Mica healthcare wine with effect of reinforcing kidneys to strengthen yang and preparation method thereof
CN106929349A (en) * 2015-12-31 2017-07-07 九芝堂股份有限公司 A kind of wine and preparation method thereof
CN107354063A (en) * 2017-06-12 2017-11-17 兰考侨兴酒业有限公司 A kind of ginseng saussurea involucrata wine
CN108504524A (en) * 2018-07-23 2018-09-07 陈玉佩 Health white wine
CN109350691A (en) * 2018-10-12 2019-02-19 皖西学院 A kind of Chinese medicine row's cadmium kidney-tonifying and sperm-producing cream and preparation method thereof
CN110862896A (en) * 2019-07-20 2020-03-06 宁波藏云玛卡生物科技有限公司 Maca saffron wine and preparation method thereof
CN115779036A (en) * 2022-11-17 2023-03-14 齐齐哈尔强能酒业制造有限公司 Health-preserving wine and preparation method thereof

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JP2007097545A (en) * 2005-10-07 2007-04-19 Suntory Ltd Maca extract-containing beverage or food blended with acetic acid or edible vinegar
CN101190308A (en) * 2006-11-20 2008-06-04 潘煜 Ginseng deer kidney-invigorating traditional Chinese medicine preparation and preparation method thereof
CN101455741A (en) * 2008-12-31 2009-06-17 云南省农业科学院高山经济植物研究所 Lepidium meyenii Walp. health wine
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Cited By (29)

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Publication number Priority date Publication date Assignee Title
CN103289876B (en) * 2013-06-26 2014-11-05 泸州品创科技有限公司 Production method of Maca health wine
CN103289876A (en) * 2013-06-26 2013-09-11 泸州品创科技有限公司 Production method of Maca health wine
CN103393109A (en) * 2013-07-31 2013-11-20 邓青 Magic maca propolis phenformin
CN103393108A (en) * 2013-07-31 2013-11-20 朱晓琳 Maca Chinese yam rejuvenating pellet
CN103468504A (en) * 2013-09-06 2013-12-25 铁岭市西丰御林鹿业集团有限公司 Pilose antler healthcare wine
CN103627600A (en) * 2013-11-21 2014-03-12 贵州鑫吾福酒业有限公司 Maca healthcare wine and preparation method thereof
CN103555537A (en) * 2013-11-25 2014-02-05 张朝峰 Pilous antler healthcare wine and mechanical preparation method thereof
CN103666967A (en) * 2013-12-09 2014-03-26 冯裕夫 Maca wine
CN103923812A (en) * 2014-05-09 2014-07-16 青海伟康生物科技有限公司 Maca wine
CN103923812B (en) * 2014-05-09 2015-09-16 青海伟康生物科技有限公司 Maca wine
CN103981070A (en) * 2014-05-14 2014-08-13 朱义 Maca nutritional health wine
CN104017706A (en) * 2014-06-27 2014-09-03 云南轩健生物科技有限公司 Maca wine
CN104017706B (en) * 2014-06-27 2016-06-08 云南轩健生物科技有限公司 A kind of Maca wine
CN104479953A (en) * 2014-11-28 2015-04-01 广西南宁劲能农业科技有限公司 Maca wine
CN104560570A (en) * 2015-01-09 2015-04-29 杨昊军 Maca juice liquor and preparation method thereof
CN104974913A (en) * 2015-08-08 2015-10-14 安国市关汉卿养生酒有限公司 Maca health-preserving wine and preparation method thereof
CN105695272A (en) * 2015-08-27 2016-06-22 泸州老窖集团养生酒业有限责任公司 Maca compound healthcare wine and production method thereof
CN106318820A (en) * 2015-08-27 2017-01-11 泸州品创科技有限公司 Healthcare wine for relieving physical fatigue and preparing method thereof
CN105296300A (en) * 2015-11-11 2016-02-03 王宝珍 Maca and ginseng liquor and production process thereof
CN106929349A (en) * 2015-12-31 2017-07-07 九芝堂股份有限公司 A kind of wine and preparation method thereof
CN106399008A (en) * 2016-05-25 2017-02-15 宁波藏云玛卡生物科技有限公司 Maca and crocus sativus wine and preparation method thereof
CN106350413A (en) * 2016-11-04 2017-01-25 江苏苏中健康产业有限公司 Compound health wine and preparation method thereof
CN106511762A (en) * 2016-12-23 2017-03-22 武汉华士特工业生物技术开发有限公司 Mica healthcare wine with effect of reinforcing kidneys to strengthen yang and preparation method thereof
CN106511762B (en) * 2016-12-23 2020-02-07 武汉华士特工业生物技术开发有限公司 Maca health-care wine capable of tonifying kidney and strengthening yang and preparation method thereof
CN107354063A (en) * 2017-06-12 2017-11-17 兰考侨兴酒业有限公司 A kind of ginseng saussurea involucrata wine
CN108504524A (en) * 2018-07-23 2018-09-07 陈玉佩 Health white wine
CN109350691A (en) * 2018-10-12 2019-02-19 皖西学院 A kind of Chinese medicine row's cadmium kidney-tonifying and sperm-producing cream and preparation method thereof
CN110862896A (en) * 2019-07-20 2020-03-06 宁波藏云玛卡生物科技有限公司 Maca saffron wine and preparation method thereof
CN115779036A (en) * 2022-11-17 2023-03-14 齐齐哈尔强能酒业制造有限公司 Health-preserving wine and preparation method thereof

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Application publication date: 20121219