CN106511526A - Traditional Chinese medicine composition for treating cough and asthma - Google Patents
Traditional Chinese medicine composition for treating cough and asthma Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine composition for treating cough and asthma. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 20-30 parts of lawn pennywort herb, 15-25 parts of loquat flowers, 15-20 parts of ficus microcarpa, 10-15 parts of cynanchum glaucescens, 1-3 parts of pepper and 3-5 parts of honey. The invention also discloses a preparation method for the traditional Chinese medicine composition for treating cough and asthma. The traditional Chinese medicine composition disclosed by the invention has the effects of moistening lung, relieving cough and reducing phlegm, can be used for treating the respiratory tract infection diseases caused by cough and cold, is safe and free from toxic or side effect and is especially suitable for the patients suffering from chronic cough and aeipathia and the weak old people.
Description
Technical field
The invention belongs to field of pharmaceutical technology, and in particular to a kind of Chinese medicine composition for treating cough cough and asthma and its preparation side
Method.
Background technology
Cough is to discharge respiratory secretions or foreign matter and a kind of body defenses reflex action for making, although favourable
One side, but chronic cough can cause hemorrhage from respiratory tract, bronchitis.Cough no matter men and women, old and young, can occur throughout the year,
Especially easily sent out when converting in season or weather with elderly and infirm.Cough has bottleneck throat itch, discomfort, rough abundant expectoration, breathing often
The symptom such as not smooth, has a strong impact on rest, the life of people.
Although the medicine for being clinically used for cough at present is a lot, majority need to coordinate antibiotics and cure effect to reach
Really, and the abuse of antibiotic can cause nervous system, kidney, hematological system to damage, the serious consequence such as resistance, allergy, curative effect
It is then not fully up to expectations.The product that Chinese medicine is the distinctive traditional Chinese medical theory of China with practice, aboundresources are with a long history, are the mankind
The natural organic substance of application, has the two-way function of nutrition and treatment, and traditional Chinese medicine concurrently to comprehensive illness of coughing earliest
Pathology and disease mechanism have more deep understanding, curative effect in terms of have an obvious advantage, prior art adopts Chinese medicine and traditional Chinese medical science pharmacology
Also there is more research by treatment cough.Such as patent name is a kind of " anti-inflammatory, cough-relieving, the Chinese medicine of resolving sputum " (patent No.:
ZL200510038327.9 patent of invention), discloses the Chinese medicine of a kind of anti-inflammatory, cough-relieving, resolving sputum, and the Chinese medicine is by cordate houttuynia, gold
Buckwheat, oldenlandia diffusa, the flower bud of lily magnolia, Radix Glycyrrhizae, Japanese Metaplexis Pericarp, process the raw materials such as loquat flower, Bombyx Batryticatus (parched), Exocarpium Citri Grandis and make, with anti-inflammatory, only
Cough, resolving sputum effect, good effect and Small side effects.And for example patent name is " cream of tonifying the lung to relieve cough " (patent No.:
ZL201210479015.1 patent of invention), discloses one kind and tonifies the lung to relieve cough cream, by the two Ten Herbs system such as Radix Codonopsis, rhizoma atractylodis macrocephalae
It is standby that into strengthening the spleen and tonifying the lung kidney-nourishing and relieving cough and reducing sputum paste, being reached by tonifying lung tonifying speen and tonifying kidney, reduction shows effect or mitigation is sent out
Make the purpose of chronic bronchitis, chronic obstructive pulmonary disease, bronchial astehma, and play prevention effect.But at present treatment is coughed
In the research of disease of coughing, there is not yet pennywort, loquat flower, Ficus microcarpa, Cynanchum glaucescens, pepper, the report of honey composition.
(1) pennywort:For samphire pennywort Hydrocotyle sibthorpioides Lamarck, Hydrocotyle sibthorpioides lam.Var.Batvachium(Hand.- Mazz.) et shan
The complete stool of HydrocotylesibthorpioidesLam.var.batrachium is dried herb.【Indication】Heat-clearing solution
Poison, removing dampness through diuresis and removing jaundice, cough-relieving, dispersing swelling and dissipating binds.For jaundice with damp-heat pathogen, cough, pertussis, abscess of throat, hot eyes cloudiness, gonorrhoea are wet
Rash, herpes zoster, sore swollen toxin, beat the stasis of blood swell.
(2) loquat flower:For rosaceous plant loquat Eriobotrya jaPon.ica (Thunb.) I, the drying of indl.
Leaf.【Function with cure mainly】Removing heat from the lung to relieve cough, stopping nausea and vomiting by lowering the adverse flow of QI.For cough with lung heat, the circulation of vital energy in the wrong direction breathes heavily urgency, and stomach energy is vomitted inverse, dysphoria and thirsty.
(3) Ficus microcarpa, is the dried leaf of moraceae plants banyan Ficus microcarpa Linnaeus f.
(4) Cynanchum glaucescens, is trailing plants section plant rhizoma et radix cynanchi stauntoni Cynanchum stauntonii (Decne.) Schltr, ex L é
Or leaves of Daphne genkwa Cynanchum glaucescens Cynanchum glaucescens vl..(Decne.) dry rhizome and root of Han.-Mazz..
(5) pepper:For the nearly ripe or ripening fruits of drying of Piperaceae plant pepper Piper nigrum L..【Function with
Cure mainly】Warming spleen and stomach for dispelling cold, lower gas, dissolving phlegm.Stomachache is had loose bowels, poor appetite, epilepsy abundant expectoration.
(6) honey:For apidae insect apis cerana Apis ceranaFabricius or apis mellifera Linnaeus Apis
The honey made by melliferaLinnaeus.【Function with cure mainly】Bowl spares, moisturizes, pain relieving, removing toxic substances;External application myogenic sore.For gastral cavity
The empty pain of abdomen, dryness of the lung dry cough, dry constipation of intestines, solution Aconitum medicine poison;Control outward sore not hold back, scald.
The content of the invention
It is an object of the invention to provide a kind of Chinese medicine composition for treating cough cough and asthma, said composition energy moistening lung, cough-relieving, change
Phlegm, application effect are good.
The present invention takes technical scheme below:
A kind of Chinese medicine composition for treating cough cough and asthma, is mainly made up of the raw material of following weight portion:Mainly by following heavy
The raw material composition of amount part:Pennywort 20-30 parts, loquat flower 15-25 parts, Ficus microcarpa 15-20 parts, Cynanchum glaucescens 10-15 parts, pepper 1-3
Part, honey 3-5 parts.
Preferably, the Chinese medicine composition of the above treatment cough cough and asthma, is mainly made up of the raw material of following weight portion:My god
25 parts of coriandrum, 20 parts of loquat flower, 18 parts of Ficus microcarpa, 12 parts of Cynanchum glaucescens, 2 parts of pepper, 4 parts of honey.
The Chinese medicine composition of the above treatment cough cough and asthma, can be prepared into pharmaceutically acceptable any preparation, preferably
Powder, granule, pill, tablet, capsule, decoction, soft extracts, mixture, oral liquid or syrup etc. are prepared into, wherein optimal preferred
Make granule.
The preparation method of the Chinese medicinal composition granules of more than one treatment cough cough and asthmas, comprises the following steps:
S1:Raw material is weighed by following weight portion:It is pennywort 20-30 parts, loquat flower 15-25 parts, Ficus microcarpa 15-20 parts, white
Front 10-15 parts, pepper 1-3 parts, honey 3-5 parts;
S2:Pennywort, loquat flower, Ficus microcarpa, Cynanchum glaucescens are taken, plus 6-8 times is measured water, heating and refluxing extraction 2-3 time, each 1-3
Hour, filtration, merging filtrate, concentration obtain thick paste;
S3:Pepper is taken, is crushed, crossed 80-100 mesh sieves, obtain pepper powder;
S4:In thick paste, soluble starch, pepper powder, honey are added, mixed, granulation is dried, obtains final product.
The preparation method of the Chinese medicinal composition granules of the above treatment cough cough and asthma, step S1 is preferably by following
Weight portion weighs raw material:25 parts of pennywort, 20 parts of loquat flower, 18 parts of Ficus microcarpa, 12 parts of Cynanchum glaucescens, 2 parts of pepper, 4 parts of honey.
The preparation method of the Chinese medicinal composition granules of the above treatment cough cough and asthma, the thick paste that step S2 is obtained
Thick paste of the relative density for 1.28-1.35 when preferably 60 DEG C.
The preparation method of the Chinese medicinal composition granules of the above treatment cough cough and asthma, baking temperature in step S4
Preferably 60-65 DEG C.
The preparation method of the Chinese medicinal composition granules of the above treatment cough cough and asthma, it is also excellent in step step S4
Choosing adds magnesium stearate.
The application of the Chinese medicine composition of the above treatment cough cough and asthma, the composition are applied to cough, flu etc. and draw
The treatment of the respiratory disease for rising, is particularly well-suited to the weaker old man of chronic cough, the patient of prolonged illness or body.
The beneficial effect that the present invention is obtained:
1. the present invention is with the peculiar Chinese medicine pennywort in Guangxi, Ficus microcarpa, with reference to medication experience among the people, with Cynanchum glaucescens, loquat flower,
Pepper shares, and adds the nutrition of supplementary needed by human body, the egg of enhance immunity and has the honey of moistening lung effect concurrently, with existing
It is formulated for scientific theory, the composition being combined into effectively plays the effect of moistening lung, cough-relieving, resolving sputum, for coughing, catching a cold
The respiratory infection diseases for causing, the such as treatment of cough, flu, cough and asthma, bronchitis, pulmonary tuberculosis etc., efficient up to 98%,
Safe without toxic side effect, is particularly well-suited to the weaker old man of chronic cough, the patient of prolonged illness or body.
2. the present invention treatment cough cough and asthma Traditional Chinese medicine composition formula science, preparation process is simple, low cost, application effect
It is really good, it is easy to accomplish industrialization.
3. the Chinese medicinal composition granules of the treatment cough cough and asthma of the present invention, utilize the bonding of honey to make in preparation method
With, step S4 prepare softwood operation in be not required to add adhesive, reduce auxiliary material use, greatly reduce production cost;
Conventional food materials pepper can reduce the loss of pepper effective active composition using being directly used as medicine after crushing.The treatment of the present invention is coughed
The traditional Chinese medicine particle of cough and asthma of coughing is formed using modern crafts by scientific process, is easy to carry, taking convenience.
Specific embodiment
For ease of more fully understanding the present invention, it is illustrated by following examples, these embodiments belong to the present invention's
Protection domain, but do not limit the scope of the invention.
First, the preparation of the traditional Chinese medicine particle for the treatment of cough cough and asthma
Embodiment 1
A kind of preparation method of the traditional Chinese medicine particle for treating cough cough and asthma, comprises the following steps:
S1:Raw material is weighed by following weight:Pennywort 20kg, loquat flower 15kg, Ficus microcarpa 15kg, Cynanchum glaucescens 10kg, pepper
1kg, honey 3kg;
S2:Pennywort, loquat flower, Ficus microcarpa, Cynanchum glaucescens, plus 6 times of amount water, heating and refluxing extraction 3 times are taken, 1 hour every time, is filtered
Cross, merging filtrate, concentrate, relative density is 1.28 thick paste when obtaining 60 DEG C;
S3:Pepper is taken, is crushed, crossed 80 mesh sieves, obtain pepper powder;
S4:In thick paste, appropriate soluble starch, pepper powder, honey are added, mixed, granulation, 60 DEG C of vacuum drying,
Obtain final product.
Embodiment 2
A kind of preparation method of the traditional Chinese medicine particle for treating cough cough and asthma, comprises the following steps:
S1:Raw material is weighed by following weight:Pennywort 30kg, loquat flower 25kg, Ficus microcarpa 20kg, Cynanchum glaucescens 15kg, pepper
3kg, honey 5kg;
S2:Pennywort, loquat flower, Ficus microcarpa, Cynanchum glaucescens, plus 8 times of amount water, heating and refluxing extraction 2 times are taken, 3 hours every time, is filtered
Cross, merging filtrate, concentrate, relative density is 1.35 thick paste when obtaining 60 DEG C;
S3:Pepper is taken, is crushed, crossed 100 mesh sieves, obtain pepper powder;
S4:In thick paste, appropriate soluble starch, pepper powder, honey are added, mixed, granulation, 65 DEG C of vacuum drying,
Obtain final product.
Embodiment 3
A kind of preparation method of the traditional Chinese medicine particle for treating cough cough and asthma, comprises the following steps:
S1:Raw material is weighed by following weight:Pennywort 25kg, loquat flower 20kg, Ficus microcarpa 18kg, Cynanchum glaucescens 12kg, pepper
2kg, honey 4kg;
S2:Pennywort, loquat flower, Ficus microcarpa, Cynanchum glaucescens, plus 7 times of amount water, heating and refluxing extraction 3 times are taken, 2 hours every time, is filtered
Cross, merging filtrate, concentrate, relative density is 1.32 thick paste when obtaining 60 DEG C;
S3:Pepper is taken, is crushed, crossed 100 mesh sieves, obtain pepper powder;
S4:In thick paste, appropriate soluble starch, magnesium stearate, pepper powder, honey are added, mixed, granulation, 65 DEG C
Vacuum drying, obtains final product.
Embodiment 4
A kind of preparation method of the traditional Chinese medicine particle for treating cough cough and asthma, comprises the following steps:
S1:Raw material is weighed by following weight:Pennywort 28kg, loquat flower 18kg, Ficus microcarpa 20kg, Cynanchum glaucescens 10kg, pepper
1kg, honey 3kg;
S2:Take pennywort, loquat flower, Ficus microcarpa, Cynanchum glaucescens, plus 10 times of amount water, heating and refluxing extraction 3 times, 1 hour every time,
Filtration, merging filtrate, concentration, when obtaining 60 DEG C, relative density is 1.26 thick paste;
S3:Pepper is taken, is crushed, crossed 200 mesh sieves, obtain pepper powder;
S4:In thick paste, appropriate soluble starch, pepper powder, honey are added, mixed, granulation, 95 DEG C of dryings are obtained final product.
2nd, application test
1. subjects selection standard
Primary symptom:Cough, without phlegm or expectoration;
Secondary disease:Pharynx is itched or pain;Dry throat;Nasal obstruction;Runny nose;It is out of breath to pant;Bronchitis;Pneumonia;Pulmonary tuberculosis;Tongue it is thin white or
It is yellow;Floating and tense pulse or cunning.
Possess 2 in above primary symptom and secondary disease, the age is in 15-80 year person, you can.
2. application scheme
Test group:By above-mentioned 3 sample of embodiment for preparing, for above-mentioned subjects.Orally, 1 sack every time
(10g), 3 times a day.Time of Administration:5 days are taken continuously.
Control group:Chuanbei pipa syrup, orally, each 10ml, 3 times a day.Time of Administration:5 days are taken continuously.
3. effect criterion
Recovery from illness:Cough symptom, sign disappear or basic disappearance, and integration reduces more than 95%.
It is effective:Cough symptom, sign are obviously improved, and integration is reduced between 70%-94%.
Effectively:Cough symptom, sign take a favorable turn, and integration is reduced in 30%-<69%.
It is invalid:Cough symptom is not improved, and very then increases, and integration is reduced<30%.
Computing formula is:[integration before (integrating after integration-treatment before treatment) ÷ treatments] × 100%
4. result is applied
The traditional Chinese medicine particle of cough and asthma that present invention treatment is coughed and the chuanbei pipa syrup of commercially available certain company's production, once
It is applied to 98 volunteers (man 45, female 53).The results detailed in Table 1.
1 application effect of products investigation result table of table
Application test result shows:The Chinese medicine composition of cough and asthma of being coughed using present invention treatment, cough recovery from illness 73%, effectively
Up to 98%, no bad reaction rate occurs, and its application effect is better than control group, illustrates that the present invention has good effect to cough,
With moistening lung, cough-relieving, resolving sputum effect, the respiratory infection diseases for causing such as can be used to coughing, catch a cold, and such as coughs, catches a cold, coughs
Breathe heavily, the treatment of bronchitis, pulmonary tuberculosis etc., safe without toxic side effect is particularly well-suited to chronic cough, the patient of prolonged illness or body more empty
Weak old man.
3rd, typical case
In addition to above-mentioned application test, the embodiment 1-4 sample of the traditional Chinese medicine particle of cough and asthma that also present invention treatment is coughed
Product are used for other volunteers, obtain good result, are several typical cases below:
Case 1:××, female, 62 years old, chronic bronchitis patient, weather turned cold outbreak, cough, and expectoration, pharynx are itched, gas
It is short to pant.Particle (embodiment 1) made by the Chinese medicine composition of present invention treatment cough cough and asthma is taken, every time 1 bag (10g), often
Day 3 times, 5 are serve on, symptom mitigation, then continuously take 5, fully recover, pay a return visit without recurrence after 1 year.
Case 2:Yellow ××, man, 80 years old, chronic pneumonia patient, cough, expectoration, shortness of breath are panted.Take present invention treatment to cough
Particle made by the Chinese medicine composition of cough and asthma of coughing (embodiment 3), 1 bag (10g) every time, 3 times a day, serve on 5, recovery from illness, 1 year
After pay a return visit without recurrence.
Case 3:Blue ××, man, 25 years old, cardinal symptom was:Cough, dry cough without phlegm, nasal obstruction, runny nose, tongue are thin white, floating pulse
Tightly.Particle (embodiment 2) made by the Chinese medicine composition of present invention treatment cough cough and asthma is taken, every time 1 bag (10g), daily 3
It is secondary, 5 are serve on, symptom eliminates, recovery from illness.
It is above-described be only the present invention preferred embodiment, it is noted that for the ordinary skill people of this area
For member, without departing from the concept of the premise of the invention, some deformations and improvement can also be made, these belong to this
Bright protection domain.
Claims (10)
1. it is a kind of treat cough cough and asthma Chinese medicine composition, it is characterised in that be mainly made up of the raw material of following weight portion:It is recklessly
Sui 20-30 parts, loquat flower 15-25 parts, Ficus microcarpa 15-20 parts, Cynanchum glaucescens 10-15 parts, pepper 1-3 parts, honey 3-5 parts.
2. the Chinese medicine composition of cough cough and asthma is treated as claimed in claim 1, it is characterised in that the main original by following weight portion
Material composition:25 parts of pennywort, 20 parts of loquat flower, 18 parts of Ficus microcarpa, 12 parts of Cynanchum glaucescens, 2 parts of pepper, 4 parts of honey.
3. the as claimed in claim 1 Chinese medicine composition for the treatment of cough cough and asthma, it is characterised in that the composition make powder,
Granule, pill, tablet, capsule, decoction, soft extracts, mixture, oral liquid or syrup.
4. the Chinese medicine composition of cough cough and asthma is treated as claimed in claim 1, it is characterised in that the composition makes particle
Agent.
5. it is a kind of it is as claimed in claim 4 treatment cough cough and asthma Chinese medicinal composition granules preparation method, it is characterised in that
Comprise the following steps:
S1:Raw material is weighed by following weight portion:Pennywort 20-30 parts, loquat flower 15-25 parts, Ficus microcarpa 15-20 parts, Cynanchum glaucescens 10-
15 parts, pepper 1-3 parts, honey 3-5 parts;
S2:Take pennywort, loquat flower, Ficus microcarpa, Cynanchum glaucescens, plus 6-8 times is measured water, heating and refluxing extraction 2-3 time, each 1-3 hours,
Filtration, merging filtrate, concentration obtain thick paste;
S3:Pepper is taken, is crushed, crossed 80-100 mesh sieves, obtain pepper powder;
S4:In thick paste, soluble starch, pepper powder, honey are added, mixed, granulation is dried, obtains final product.
6. the preparation method of the Chinese medicinal composition granules of cough cough and asthma is treated as claimed in claim 5, it is characterised in that described
Step S1 weighs raw material by following weight portion:25 parts of pennywort, 20 parts of loquat flower, 18 parts of Ficus microcarpa, 12 parts of Cynanchum glaucescens, 2 parts of pepper,
4 parts of honey.
7. the preparation method of the Chinese medicinal composition granules of cough cough and asthma is treated as claimed in claim 5, it is characterised in that described
Thick paste of the relative density for 1.28-1.35 when the thick paste that step S2 is obtained is 60 DEG C.
8. the preparation method of the Chinese medicinal composition granules of cough cough and asthma is treated as claimed in claim 5, it is characterised in that described
In step S4, baking temperature is 60-65 DEG C.
9. the preparation method of the Chinese medicinal composition granules of cough cough and asthma is treated as claimed in claim 5, it is characterised in that described
Magnesium stearate is additionally added in step step S4.
10. a kind of application of the Chinese medicine composition for the treatment of cough cough and asthma as claimed in claim 1, it is characterised in that the combination
Thing is for coughing, the treatment of the respiratory disease for causing of catching a cold.
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Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN101195007A (en) * | 2006-12-05 | 2008-06-11 | 凌沛学 | Medicament for treating common cold cough, method for preparing its preparation and quality control method thereof |
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2016
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