CN102641421A - Figwort Shangqing gula tablet - Google Patents
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Abstract
The invention relates to the technical field of medicine and health products and particularly discloses a figwort Shangqing gula tablet. A preparation method of the figwort Shangqing gula tablet comprises the following steps of: mixing figwort, fructus arctii, ophiopogonis tuber, fructus terminaliae, fructus canarii, platycodon root, radices paeoniae rubra, flos lonicerae, boat-fruited sterculia and licorice root based on amounts in a formula, adding water ten times of the total weight of the medicinal materials in the medicinal materials, decocting and extracting the medicinal materials twice, combining the extraction solutions and then filtering the extracting solution, decompressing and concentrating filter liquor to clear paste with the relative density being 1.25 to 1.27 (measured at 60 DEG C), adding dextrin in the clear paste, mixing the dextrin and the clear paste, decompressing and drying the mixture through microwaves, smashing the dried mixture to fine powder, adding auxiliary materials in the fine powder, granulating the fine powder through ethanol of 75% (v/v), and drying the granulated fine powder at 60 to 70 DEG C to obtain dry granules; and dissolving menthol crystals in ethanol of 95% (v/v), adding the dissolved menthol crystals in the dry granules, keeping the mixture to be airtight for 30 minutes, adding magnesium stearate in the mixture, mixing the magnesium stearate and the mixture uniformly, and then pressing the new mixture to oval tablets. The specification of the tablet equals to 1.0g per tablet. The figwort Shangqing gula tablet is scientific and reasonable in formula, optimal in process, stable in product quality, convenient to take orally and good in curative effect, thus having a great market application prospect.
Description
Technical field
The present invention relates to the Medicines and Health Product technical field, particularly a kind of Radix Scrophulariae supernatant YANHOU PIAN.
Background technology
People's bottleneck throat disease is a common frdquently encountered disease; Like pharyngitis, laryngitis etc.; Pharynx, laryngitis are bottleneck throat mucosa, submucous tissue and adenoid acute and chronic inflammation, particularly chronic pharyngolaryngitis, are difficult to for a long time cure; People's life, working and learning and normal productive labor have been brought influence in various degree, healthy totally unfavorable to the people.Therefore; People are studying how to prevent and treat the bottleneck throat disease always, particularly prevent and treat pharyngolaryngitis, and the medicine that is used to prevent and treat pharyngolaryngitis at present is a lot; Like Chinese and western drugses such as various mouthfuls of food YANHOU PIAN, siren throat lozenge, JIANMIN YINHOU PIAN, LIUSHEN WAN, detoxifying pills, gentamycin, dexamethasone; But for various reasons, the prevention effect of these medicines can not be satisfactory, and people are sought after taking convenience, novel drugs effective, that price is low occurs.
Chinese patent CN 101607001B discloses a kind of throat tablet for moisturizing and removing heat of being processed by Radix Scrophulariae 230-250g, Fructus Arctii 150-170g, Fructus Canarii 150-170g, Radix Platycodonis 150-170g, Radix Paeoniae Rubra 150-170g, Radix Puerariae 150-170g, Radix Rehmanniae 70-90g, Fructus Momordicae 220g-260g and Radix Glycyrrhizae 110-130g, wherein, each component is mixed; Add medicine gross weight 8-10 decocting doubly boils 2 times at every turn; Each 1.5-2 hour, merge decoction liquor twice, filter; Measuring relative density when filtrate decompression is concentrated into 60 ° of C is the clear paste of 1.23-1.25; Vacuum drying is ground into fine powder to doing under vacuum 0.06-0.08MPa, temperature 70-80 ° C again, and compacting in flakes.There are some unreasonable parts in this cleaning throat and moistening larynx slice prescription, therefore fail to obtain laryngopharyngitis best treatment and preventive effect; Method for preparing in this patent is not clearly processed total amount, and sheet is heavy, sheet shape is not clear and definite, and the extraction process among the preparation technology is not perfect, and dry through conventional vacuum, efficient is low and the production cycle is long, can destroy effective ingredient.
Summary of the invention
To the deficiency that exists in the prior art, the object of the present invention is to provide a kind of Radix Scrophulariae supernatant YANHOU PIAN.
A kind of Radix Scrophulariae supernatant YANHOU PIAN is characterized in that, is prepared from following raw materials in weight portion:
Preferred parts by weight of raw materials proportioning is following:
Optimum material weight portion proportioning is following:
The method for preparing of the Radix Scrophulariae supernatant YANHOU PIAN in above-mentioned each technical scheme is all following: 10 flavor medical material Radix Scrophulariaes, Fructus Arctii, Radix Ophiopogonis, Fructus Chebulae, Fructus Canarii, Radix Platycodonis, Radix Paeoniae Rubra, Flos Lonicerae, Semen Sterculiae Lychnophorae, the Radix Glycyrrhizae of formula ratio are mixed, add the water of 10 times of medical material gross weights at every turn, 100 ℃ decoct extraction 2 times down; Each 1 hour, merge extracted twice liquid, filter; Measuring relative density when filtrate decompression concentrates (vacuum 0.05-0.07Mpa, temperature 65-80 ℃) to 60 ℃ is the clear paste of 1.25-1.27, adds dextrin and mixes; Microwave drying under reduced pressure (vacuum 0.06-0.08Mpa, 7090 ℃ of temperature) is ground into fine powder (pharmacopeia has regulation) to doing (can accomplish in 2-3 hour); Add adjuvant mannitol, microcrystalline Cellulose and aspartame; With the alcohol granulation of 75% (v/v), 60-70 ℃ of drying, it is subsequent use to do granule; Get Mentholum,, join in the dried granule with 95% (v/v) dissolve with ethanol, airtight 30 minutes, add magnesium stearate again, mix homogeneously is pressed into oval tablet (1.0 gram/sheet), steady quality (put dry place, the shelf-life is 24 months), it is convenient to contain food.
The applicant is based on the understanding to the pharyngolaryngitis disease cause of disease, pathogenesis, method of treatment.Fang Xiewei of the present invention:
Radix Scrophulariae, sweet in the mouth, hardship, salty; Cold nature.Return lung, stomach, kidney channel.Clearing away heat and cooling blood, eliminating fire and detoxication, YIN nourishing.Cure mainly pathogenic warmth and join the army, the pericardium that caves in, maculae caused by violent heat pathogen, constipation, hectic fever due to YIN-deficiency chronic cough, conjunctival congestion, pharyngalgia, scrofula, diphtheria, carbuncle sore tumefacting virus are hindered in consumption of YIN caused by febrile disease, crimson tongue excessive thirst, Tianjin.
Fructus Arctii, acrid in the mouth, hardship; Cold in nature.Attach to the lung and stomach meridians.Dispelling wind and heat pathogens; The heat-clearing and toxic substances removing rash; The lung qi dispersing sore-throat relieving looses swollen.
Radix Ophiopogonis, sweet, little hardship is slightly cold.GUIXIN, lung, stomach warp.YIN nourishing and the production of body fluid promoting, lung moistening clears away heart-fire.Be used for dryness of the lung dry cough, deficiency of YIN consumptive disease is coughed, the sore throat pharyngalgia, and Tianjin wound is thirsty, and interior-heat is quenched one's thirst, vexed insomnia, dryness of the intestine constipation.
The Fructus Chebulae, bitter, acid, puckery, flat.Return lung, a big warp.Astringing intestine to stop diarrhea is astringed the lung, sending down the abnormal ascending QI, sore-throat relieving.Be used for that chronic diarrhea, chronic dysentery, proctoptosis, the deficiency of the lung are breathed with cough, chronic cough aphonia.
Fructus Canarii, property is flat, sweet in the mouth, acid.Heat clearing away, sore-throat relieving promotes the production of body fluid, detoxifcation.Be used for laryngopharynx swelling and pain, cough, excessive thirst, the poisoning of fish Eriocheir sinensis etc.
Radix Platycodonis is bitter, hot, flat.Return lung meridian.Lung qi dispersing, sore-throat relieving eliminates the phlegm, evacuation of pus.Be used for cough with copious phlegm, pharyngalgia, aphonia, lung abscess vomiting pus.
Radix Paeoniae Rubra, hardship is slightly cold.Return Liver Channel.Clearing away heat and cooling blood, eliminating stasis to stop pain.Be used for maculae caused by violent heat pathogen, hematemesis and epistaxis, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea, lump in the abdomen stomachache, injury from falling down, carbuncle skin infection.
Flos Lonicerae, sweet, cold.Return lung, the heart, stomach, large intestine channel.Heat-clearing and toxic substances removing, dispelling wind and heat pathogens.Be used for affection due to external wind and heat, epidemic febrile disease heating, carbuncle skin ulcer pain, laryngopharynx swelling and pain, pyretic toxicity dysentery.
Semen Sterculiae Lychnophorae, sweet, cold.Return lung, large intestine channel.Removing heat from the lung and relieving sorethroat, loosening bowel to relieve constipation.Be used for phlegm-heat cough, pharyngalgia hoarseness, constipation with heat retention, headache conjunctival congestion.
Radix Glycyrrhizae, sweet, flat.GUIXIN, spleen, lung, stomach warp.Invigorating the spleen and replenishing QI, nourishing the lung to arrest cough, heat-clearing and toxic substances removing is alleviated pain relieving, relaxes the property of medicine.Be used for weakness of the spleen and stomach, shortness of breath and fatigue, the cardiopalmus severe palpitation, cough expectorant is few, pathopyretic ulcer, the medicine food is poisoned gastral cavity abdomen shoot, limb pain twin.
Compared with prior art, advantage of the present invention and beneficial effect are:
1, prescription compatibility science of the present invention, consumption is reasonable, is prone to take, and cost is low, and is effective, is the innovation on the control bottleneck throat disease medicament, and economic and social benefit is remarkable.
2, Radix Scrophulariae supernatant YANHOU PIAN medicine components of the present invention is a medicine-food two-purpose, proves to have treatment, prevention and the health care of cleaning throat and moistening larynx through animal and human's body test-meal function test.
3, each component organic assembling in the raw material of the present invention supports to have blood circulation promoting and blood stasis dispelling mutually, the detumescence cough-relieving, and effects such as relieving sore-throat by clearing away heat just in time are beneficial to control bottleneck throat disease.
4, the present invention has adopted the microwave drying under reduced pressure in preparation technology, has shortened drying time greatly, only needs 2-3 hour; Need 48-72 hour and conventional vacuum is dry; Therefore active ingredient destroys and lacks, and the quality of gained finished product is more guaranteed, and has significantly improved production efficiency.
The specific embodiment
Following applicant will combine concrete embodiment that the inventive method is done further detailed description, should be understood that following examples only are used to set forth the present invention, but in all senses, not be interpreted as the restriction to protection domain of the present invention.
Embodiment 1
A kind of Radix Scrophulariae supernatant YANHOU PIAN, its preparation method is: with Radix Scrophulariae 130g, Fructus Arctii 120g, Radix Ophiopogonis 110g, Fructus Chebulae 100g, Fructus Canarii 80g, Radix Platycodonis 80g, Radix Paeoniae Rubra 80g, Flos Lonicerae 50g, Semen Sterculiae Lychnophorae 50g, this 10 flavor medical material of Radix Glycyrrhizae 50g mix, add the water of medical material gross weight 10 times (8.5Kg) at every turn; 100 ℃ decoct extraction 2 times down, each 1 hour, merge extracted twice liquid; Filter, the mensuration relative density was 1.26 clear paste when filtrate decompression concentrated (vacuum 0.06Mpa, 70 ℃ of temperature) to 60 ℃; Add the 420g dextrin and mix, microwave drying under reduced pressure (vacuum 0.07Mpa, 80 ℃ of temperature) is to doing; Be ground into fine powder, add 200g mannitol, 80g microcrystalline Cellulose and 6g aspartame, with the alcohol granulation of 75% (v/v); 65 ℃ of dryings, it is subsequent use to do granule; Get the 8g Mentholum,, join in the dried granule with 95% (v/v) dissolve with ethanol, airtight 30 minutes, add the 2g magnesium stearate again, mix homogeneously is pressed into 1000 tablets of oval tablets (1.0g/ sheet), steady quality, the shelf-life is 24 months.The content of Arctiin is 0.35g/100g in the gained Radix Scrophulariae supernatant YANHOU PIAN, and major function is a cleaning throat and moistening larynx, and suitable crowd contains food for pharynx and/or the discomfort person of throat, and mouthfeel is good.
The application implementation example:
The Radix Scrophulariae supernatant YANHOU PIAN that embodiment 1 is made has been obtained very good effect through clinic trial, and relevant experiment situation is following:
One, aspect treatment, be example with pharyngitis, pharyngolaryngitis
A, age pharyngitis patient diagnosed 320 people more than 16 one full year of life, symptom many with foreign body in pharynx sense, drying, to itch be main, mucosa has kermesinus, the pharynx rear wall has the lymph follicle that is dispersed in; Secretions adhesion etc. is arranged, and disease time is 3-30 days, and the longest medical history is more than 6 years, through the Radix Scrophulariae supernatant YANHOU PIAN with the embodiment of the invention 1; Every day 5 times, each 1, buccal; Cured in acute patient 2-5 days, i.e. symptom complete obiteration recovers normal; Chronic patients 20-50 days transference cures, recovering normal person is 218 people, wherein acute 69 people; Recover normal person and account for total 320 people's 68.1%, various symptoms have improver 99 people in various degree, account for total 320 people's 30.9%; No positive effect person 3 people account for 0.94%, and total effective rate is 99.1%.Period in a medicine has no side effect to the heart, liver, kidney, hemopoietic system etc., does not also produce the digestive tract irritation.
B, uncomfortable to bottleneck throat; Treat like partial symptoms patient 139 people such as pharynx, throat's redness, itching throat, pharyngalgia, cough, hoarseness; Suck the Radix Scrophulariae supernatant YANHOU PIAN of the clothes embodiment of the invention 1 every day for 5 times, each 1, all had symptom in various degree to take a turn for the better in 2-8 days; It is comfortable that the patient feels, all can consolidate more than 28 days.Period in a medicine has no side effect to the heart, liver, kidney, hemopoietic system etc., does not also produce the digestive tract irritation.
Two, about the prevention situation
To healthy population, take through 520 people, every day 5 times, each 1, buccal, the bottleneck throat disease incidence is a less than 2/1000ths in 3 years, only has 1 people to take place, and does not have any untoward reaction; And through at same environment, the crowd under the similarity condition adds up sickness rate more than 40%, and obvious prevention effect of the present invention is very outstanding.
Three, model case
Example 1, Wang Baixiong, the man, 44 years old, the cadre told regular pharyngalgia, pharyngeal discomfort; Dry pharynx accompanying sound sound is hoarse, the pronunciation fatiguability, and nearly 2 years of dry cough, the inspection pharyngeal mucous membrane is dark red, and lymph follicle is big, and vocal cords are light dark red; The edge is blunt slightly, and is gapped when closed, larynx mucosa mild hyperaemia, and stringy,thready and rapid pulse, the few tongue of light red tongue is diagnosed as the chronic pharyngolaryngitis hyperactivity of deficient fire; With the Radix Scrophulariae supernatant YANHOU PIAN buccal that embodiment 1 makes, every day 5 times, each 1, serve on 7 days after the check celostomia obviously alleviate, inspection pharyngeal mucous membrane hyperemia obviously alleviates, vocal cords and larynx mucous hyperemia obviously alleviate; Continued to take 7 days, dry pharynx, pharynx is uncomfortable, and pharyngalgia disappears basically, celostomia, dry cough disappears; The inspection pharyngeal mucous membrane is congested to disappear, and lymph follicle obviously dwindles, vocal cords, and the larynx mucous hyperemia disappears basically, closure.
Example 2, Liu Xiaoyu, the woman, 35 years old, the teacher told discontinuity pharyngalgia companion dry cough two-and-a-half years; And companion's pharynx is stifled, pharyngeal abundant expectoration, and foreign body sensation is not looked into, the pharyngeal mucous membrane chronic congestion; Tonsil I ° big, and the pharynx rear wall has the lymph grain growth, lateral pharyngeal band lymphadenosis, the few tongue of red tongue, thready and rapid pulse.The diagnosing chronic pharyngitis, hyperactivity of deficient fire.With the Radix Scrophulariae supernatant YANHOU PIAN buccal that embodiment 1 makes, every day 5 times, each 1; Tell after serveing on 7 days pharyngalgia, the pharynx foreign body sensation obviously alleviate; Pharyngeal mucous membrane hyperemia also obviously alleviates, and continues to take 7 days, and pharyngalgia, dry cough, pharyngeal abundant expectoration, foreign body sensation disappear basically; Pharyngeal mucous membrane hyperemia is disappeared, and pharyngeal lymphoid tissue is also obviously dwindled.
Example 3, Liu Xing, the woman, 32 years old, the company clerk, the violent pharyngalgia of burst after suffering from cold, dysphagia, headache, weak, cough, thick sputum, epistaxis, thirsty polydipsia, appetite descends, heating, it is more dried to defecate, yellowish or reddish urine.Inspection: see pharyngeal congestion, color is scarlet, the about 1 * 2cm of right submandibular lymph nodes enlargement, and xerocheilia, red tongue, yellow and thin fur, rapid pulse is strong, 38.0 ℃ of body temperature.Be diagnosed as acute pharyngitis.
With the Radix Scrophulariae supernatant YANHOU PIAN buccal that embodiment 1 makes, every day 5 times, each 1 treatment.Medication pharyngalgia on the 2nd begins to alleviate.Medication after 3 days symptom such as pharyngalgia, headache and pharyngeal sign greatly alleviate, 37.4 ℃ of body temperature, appetite is normal.After the medication 5 days, the symptom and the sign of its acute pharyngitis all disappear, 36.9 ℃ of body temperature, recovered and discharged.
Example 4, Bai Qin, the man, 24 years old, the driver had the smoking history of drinking history, had sore throat over nearly 3 years and showed effect repeatedly, or seek medical advice to hospital, or buy common YANHOU PIAN by oneself and treat, and can alleviate some symptoms, but pharyngeal uncomfortable all the time, often felt dried itching, the irritative cough.Throat sharp ache after suffering from cold before 2 days, refreshing tired, dry cough without phlegm is asked drink frequently.Inspection: pharyngeal congestion is kermesinus, and mucosa is dry, red tongue, and thin fur is few, thready and rapid pulse, 37.3 ℃ of body temperature are diagnosed as chronic pharyngitis.
With the Radix Scrophulariae supernatant YANHOU PIAN buccal that embodiment 1 makes, every day 5 times, each 1 treatment, medication is after 3 days, and pharyngalgia begins to alleviate, and treats after 10 days, and pharyngalgia disappears basically, and idol has cough, and the pharyngeal mucosa color is normal basically.Treated for three weeks, transference cures such as pharyngalgia, cough, picture of the tongue, pulse condition are normal; Inspection: pharyngeal normal, 36.9 ℃ of body temperature, disease recovery from illness.
Claims (3)
1. a Radix Scrophulariae supernatant YANHOU PIAN is characterized in that, is prepared from following raw materials in weight portion:
Parts by weight of raw materials
Radix Scrophulariae 110-150,
Fructus Arctii 100-140,
Radix Ophiopogonis 90-130,
Fructus Chebulae 80-120,
Fructus Canarii 60-100,
Radix Platycodonis 60-100,
Radix Paeoniae Rubra 60-100,
Flos Lonicerae 35-75,
Semen Sterculiae Lychnophorae 35-75,
Radix Glycyrrhizae 35-75,
Mentholum 6-10,
Dextrin 390-450,
Mannitol 170-220,
Microcrystalline Cellulose 60-100,
Aspartame 3-9,
Magnesium stearate 0.5-4;
The method for preparing of said Radix Scrophulariae supernatant YANHOU PIAN is following: 10 flavor medical material Radix Scrophulariaes, Fructus Arctii, Radix Ophiopogonis, Fructus Chebulae, Fructus Canarii, Radix Platycodonis, Radix Paeoniae Rubra, Flos Lonicerae, Semen Sterculiae Lychnophorae, the Radix Glycyrrhizae of above-mentioned formula ratio are mixed, add the water of 10 times of medical material gross weights at every turn, 100 ℃ decoct extraction 2 times down; Each 1 hour, merge extracted twice liquid, filter; Filtrating is at vacuum 0.05-0.07 Mpa, and measuring relative density when being evaporated to 60 ℃ under temperature 65-80 ℃ is the clear paste of 1.25-1.27, adds dextrin and mixes; At vacuum 0.06-0.08 Mpa, temperature 70-90 ℃ of following microwave drying under reduced pressure is ground into fine powder; Add adjuvant mannitol, microcrystalline Cellulose and aspartame; With the alcohol granulation of 75%v/v, 60-70 ℃ of drying, it is subsequent use to do granule; Get Mentholum, use the 95%v/v dissolve with ethanol, join in the dried granule, airtight 30 minutes, add magnesium stearate again, mix homogeneously is pressed into the oval tablet of 1.0 gram/sheets.
2. Radix Scrophulariae supernatant YANHOU PIAN according to claim 1 is characterized in that, is joined by following weight portion
The feedstock production of ratio forms:
Parts by weight of raw materials
Radix Scrophulariae 120-140,
Fructus Arctii 110-130,
Radix Ophiopogonis 100-120,
Fructus Chebulae 90-110,
Fructus Canarii 70-90,
Radix Platycodonis 70-90,
Radix Paeoniae Rubra 70-90,
Flos Lonicerae 40-60,
Semen Sterculiae Lychnophorae 40-60,
Radix Glycyrrhizae 40-60,
Mentholum 6-10,
Dextrin 400-440,
Mannitol 180-220,
Microcrystalline Cellulose 90-100,
Aspartame 5-7,
Magnesium stearate 1-3.
3. Radix Scrophulariae supernatant YANHOU PIAN according to claim 1 and 2, its preparation method is: with Radix Scrophulariae 130g, Fructus Arctii 120g, Radix Ophiopogonis 110g, Fructus Chebulae 100g, Fructus Canarii 80g, Radix Platycodonis 80g, Radix Paeoniae Rubra 80g, Flos Lonicerae 50g, Semen Sterculiae Lychnophorae 50g, Radix Glycyrrhizae 50g totally 10 flavor medical materials mix, add the water of 10 times of medical material gross weights at every turn; 100 ℃ decoct extraction 2 times down, each 1 hour, merge extracted twice liquid; Filter, filtrating is at vacuum 0.06Mpa, measures relative density when being evaporated to 60 ℃ under 70 ℃ of the temperature and be 1.26 clear paste; Add the 420g dextrin and mix, at vacuum 0.07Mpa, 80 ℃ of following microwave drying under reduced pressure of temperature are to doing; Be ground into fine powder, add 200g mannitol, 80g microcrystalline Cellulose and 6g aspartame, with the alcohol granulation of 75v/v%; 65 ℃ of dryings, it is subsequent use to do granule; Get the 8g Mentholum, use the 95v/v% dissolve with ethanol, join in the dried granule, airtight 30 minutes, add the 2g magnesium stearate again, mix homogeneously is pressed into the oval tablet of 1,000 1.0 gram/sheets.
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| CN103054927A (en) * | 2013-01-31 | 2013-04-24 | 成都中医药大学 | Sore-throat-relieving buccal tablet and preparation method thereof |
| CN103584115A (en) * | 2013-11-07 | 2014-02-19 | 李智祥 | Health-care food for clearing heat from throat and removing haze |
| CN104689002A (en) * | 2013-12-05 | 2015-06-10 | 天津嘉瑞生物科技有限公司 | Traditional Chinese medicine oral liquid for treating laryngitis of pet dog and preparation method of traditional Chinese medicine oral liquid |
| CN105148037A (en) * | 2015-09-22 | 2015-12-16 | 陈华祥 | Traditional Chinese medicine used for treating sphagitis |
| CN107596107A (en) * | 2017-10-11 | 2018-01-19 | 广西昌弘制药有限公司 | A kind of clearing heat, relieving sore-throat antiallergy Chinese medicine preparation and preparation method thereof |
| CN108992566A (en) * | 2018-10-02 | 2018-12-14 | 李洋 | A kind of Chinese olive Liyan Keli and preparation method thereof suitable for children |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103054927A (en) * | 2013-01-31 | 2013-04-24 | 成都中医药大学 | Sore-throat-relieving buccal tablet and preparation method thereof |
| CN103584115A (en) * | 2013-11-07 | 2014-02-19 | 李智祥 | Health-care food for clearing heat from throat and removing haze |
| CN103584115B (en) * | 2013-11-07 | 2015-10-28 | 王昆磊 | Clearing is except haze health food |
| CN104689002A (en) * | 2013-12-05 | 2015-06-10 | 天津嘉瑞生物科技有限公司 | Traditional Chinese medicine oral liquid for treating laryngitis of pet dog and preparation method of traditional Chinese medicine oral liquid |
| CN105148037A (en) * | 2015-09-22 | 2015-12-16 | 陈华祥 | Traditional Chinese medicine used for treating sphagitis |
| CN107596107A (en) * | 2017-10-11 | 2018-01-19 | 广西昌弘制药有限公司 | A kind of clearing heat, relieving sore-throat antiallergy Chinese medicine preparation and preparation method thereof |
| CN108992566A (en) * | 2018-10-02 | 2018-12-14 | 李洋 | A kind of Chinese olive Liyan Keli and preparation method thereof suitable for children |
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| CN102641421B (en) | 2013-09-04 |
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