CN103041215B - Chinese medicament composition for treating hashimoto thyroiditis - Google Patents
Chinese medicament composition for treating hashimoto thyroiditis Download PDFInfo
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- CN103041215B CN103041215B CN201310014359.XA CN201310014359A CN103041215B CN 103041215 B CN103041215 B CN 103041215B CN 201310014359 A CN201310014359 A CN 201310014359A CN 103041215 B CN103041215 B CN 103041215B
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Abstract
The invention relates to a Chinese medicament for treating hashimoto thyroiditis. The Chinese medicament is prepared from marigold flowers, thorn langguo fruits, popcorn flowers, frangipani, knife ash trees, tangerine kernels, pinellia ternate, inula flowers, lemmaphyllum microphyllum, cortex dictamni, anise and annatto fragrance. The Chinese medicament can be clinically used for treating the hashimoto thyroiditis.
Description
Technical field
The invention belongs to technical field of Chinese medicines, especially relate to a kind of Chinese medicine composition for the treatment of chronic lymphocytic thyroiditis.
Background technology
Chronic lymphocytic thyroiditis (HT) is a kind of common autoimmune thyroid disease clinically, the acidophilia who shows as diffusivity lymphocytic infiltration, fibrosis, interstitial atrophy and acinous cell due to the histologic characteristics of primary disease changes, therefore also referred to as chronic lymphocytic thyroiditis.Primary disease is apt to occur in 30～50 years old women, and its sickness rate is the trend increasing gradually in recent years.Western medical treatment primary disease is taked thyroxin alternative medicine, immunotherapy, operative treatment etc. more at present, and curative effect is sure, but untoward reaction is many, and easily recurrence.The traditional Chinese medicine composition for treating chronic lymphocytic thyroiditis that the present invention prepares, has obtained good effect.
Summary of the invention
The object of the present invention is to provide the Chinese medicine composition of the treatment chronic lymphocytic thyroiditis that a kind of therapeutic effect is good, effective percentage is high, human body is had no side effect.
The object of the present invention is achieved like this, according to Chinese medical theory, utilizes the property of medicine of Chinese medicine uniqueness, adopt marigold flower, thorn youth fruit, popcorn, Flos Plumeriae Acutifoliae, cutter ash tree, Fructus Citri tangerinae core, the Rhizoma Pinelliae, Flos Inulae, Drymoglossum Herba Drymoglossi, Cortex Dictamni, anise, Radix Kadsurae longipedunculatae is made, according to certain compatibility requirement, through being processed into.
Preparing Chinese medicine composition of the present invention is made by following raw material medicaments: marigold flower 40-70 part, thorn youth fruit 30-50 part, popcorn 30-50 part, Flos Plumeriae Acutifoliae 30-50 part, cutter ash tree 20-30 part, Fructus Citri tangerinae core 20-30 part, Rhizoma Pinelliae 10-20 part, Flos Inulae 20-30 part, Drymoglossum Herba Drymoglossi 10-20 part, Cortex Dictamni 8-15 part, anistree 8-15 part, Radix Kadsurae longipedunculatae 8-15 part.
Optimum weight part of traditional Chinese medicinal composition raw materials of the present invention is: 55 parts of marigold flowers, 40 parts of thorn youth fruits, 40 parts of popcorn, 40 parts of Flos Plumeriae Acutifoliaes, 25 parts of cutter ash trees, 25 parts of Fructus Citri tangerinae cores, 15 parts of the Rhizoma Pinelliaes, 25 parts of Flos Inulaes, 15 parts of Drymoglossum Herba Drymoglossis, 12 parts of Cortex Dictamni, anistree 12 parts, 10 parts of Radix Kadsurae longipedunculataes.
The pharmacological action of Chinese medicine of the present invention is as follows:
Marigold flower: bitter, cool.Heat-clearing and toxic substances removing, cough-relieving.For anemopyretic cold, cough, dysentery, parotitis, acute mastitis, toothache, oral inflammation, conjunctival congestion and swelling pain.
Thorn youth fruit: bitter, pungent, flat.Heat-clearing and toxic substances removing, anti-inflammatory analgetic.For icterohepatitis, stomachache, rheumatic arthritis, acute conjunctivitis, pharyngolaryngitis, periodontitis, the diseases such as lymphadenitis.
Popcorn: sweet, cool.Depressed liver-energy dispersing and function of gallbladder promoting.For hepatitis, cholecystitis.
Flos Plumeriae Acutifoliae: sweet, micro-hardship, cool.Return lung, large intestine channel.Heat clearing away, dampness removing, expelling summer-heat.For cold, fever, cough due to lung-heat, jaundice due to damp-heat, dysentery, lithangiuria, prevention heatstroke.
Cutter ash tree: sweet, flat.Hemostasia and promoting granulation, and liver spleen.For traumatic hemorrhage, spit blood, spitting of blood, furuncle, infantile malnutrition, the diseases such as eye conjunctivitis.
Fructus Citri tangerinae core: flat, bitter, return liver, kidney channel.Regulate the flow of vital energy, eliminating stagnation, pain relieving.For inguinal hernia, painful and swollen testis, acute mastitis swells and ache.
The Rhizoma Pinelliae: pungent, warm.Return spleen, stomach, lung meridian.Drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass.Cure mainly cough with asthma abundant expectoration, feeling of oppression and fullness in the chest and epigastrium, has a headache dizzy etc.
Flos Inulae: bitter, pungent, salty, tepor.Lung, stomach, large intestine channel.Expectorant clear water, sending down the abnormal ascending QI preventing or arresting vomiting.Sticky for cough with asthma expectorant, the eructation of trembling, feeling of stuffiness in chest hypochondriac pain etc.
Drymoglossum Herba Drymoglossi: sweet, light, micro-cool.Return liver, lung meridian.Heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, hemostasis.For jaundice due to damp-heat, conjunctival congestion and swelling pain, parotitis, lymphadenitis, traumatic injury.
Cortex Dictamni: bitter, cold, return spleen, stomach warp.Heat clearing and damp drying, the removing toxic substances of dispeling the wind.Outward for herpes simplex poison, eczema scabies.
Anistree: pungent, sweet, warm.Return liver,kidney,spleen, stomach warp.Cold expelling, regulate the flow of vital energy, pain relieving.For colic of cold type stomachache, chills and pain of the waist and kness, fear of cold vomiting, the disturbance of lower legs due to pathogenic cold and dampness etc.
Radix Kadsurae longipedunculatae: acrid, bitter, warm.Return spleen, stomach, Liver Channel.Regulating QI to relieve pain, dispelling wind and removing obstruction in the collateral, promoting blood circulation and detumescence.For stomachache, stomachache, rheumatic arthralgia, dysmenorrhea, menoxenia, puerperal abdonimal pain, duodenal ulcer, laryngopharynx swelling and pain, hemorrhoid, innominate toxic swelling, traumatic injury etc.
Chronic lymphocytic thyroiditis does not have corresponding name of disease in Chinese medicine, belongs to " goiter " category, and the factor relations such as main and plain body deficiency, feelings will internal injury, six evil, drinking and eating irregularly are close, cause it qi-blood disharmony, and the stagnation of QI, expectorant are solidifying, blood stasis is stopped up in throat and formed.Marigold flower of the present invention has the effect of heat-clearing and toxic substances removing, is monarch drug, thorn youth fruit anti-inflammatory analgetic, popcorn depressed liver-energy dispersing and function of gallbladder promoting, Flos Plumeriae Acutifoliae heat clearing away, is ministerial drug, cutter ash tree and liver spleen, Fructus Citri tangerinae core is regulated the flow of vital energy, eliminating stagnation, pain relieving, Rhizoma Pinelliae dissolving lump and resolving mass, Flos Inulae clearing away phlegm diuretic, Drymoglossum Herba Drymoglossi dispersing swelling and dissipating binds, Cortex Dictamni heat clearing and damp drying, anise is regulated the flow of vital energy, pain relieving, Radix Kadsurae longipedunculatae dispelling wind and removing obstruction in the collateral, promoting blood circulation and detumescence, altogether long memorial liver spleen, activating QI to eliminate phlegm, the effect of the wart that disappears eliminating stagnation, reaches the object for the treatment of chronic lymphocytic thyroiditis.
Chinese medicine composition of the present invention is used in 2007 to 2011 clinical observation chronic lymphocytic thyroiditis disease 53 routine patients, and clinical report is as follows:
1, physical data
In 53 routine patients, women's 41 examples, male's 12 examples, minimum 18 years old of age, maximum 62 years old, 35.6 years old mean age.The equal enlargement of thyroid.
2, diagnostic criteria
(1) the scleroid goiter of diffusivity.
(2) TgAb (thyroglobulin antibody) and TmAb (thyroid microsomal antibody) significantly increase or reduce with FT4 (serum free thyroxine), FT3 (free serum 3).
(3) thyroid fine needle pathology examination by centesis.
3, Therapeutic Method
3.1 prescriptions: marigold flower 55g, thorn youth fruit 40g, popcorn 40g, Flos Plumeriae Acutifoliae 40g, cutter ash tree 25g, Fructus Citri tangerinae core 25g, Rhizoma Pinelliae 15g, Flos Inulae 25g, Drymoglossum Herba Drymoglossi 15g, Cortex Dictamni 12g, anistree 12g, Radix Kadsurae longipedunculatae 10g.
3.2 preparation methoies: said medicine routinely technique is made decoction.
3.3 instructions of taking: each 1 dose every day 2 times, 30 days was 1 course for the treatment of.
4, therapeutic outcome:
4.1 with reference to < < traditional Chinese medical science disease Standardization of diagnosis and curative effect > >:
Cure: clinical symptom disappearance, thyroid is without enlargement, and TgAb, TmAb, FT4, FT3 level are normal;
Take a turn for the better: clinical symptoms obviously alleviates, thyromegaly dwindle exceed 50%, TgAb, TmAb, FT4, FT3 are on close level normally;
Effective: clinical symptoms alleviates to some extent, thyromegaly dwindles, and TgAb, TmAb, FT4, FT3 level are improved;
Do not heal: goiter is dwindled not obvious or without dwindling, TgAb, TmAb, FT4, FT3 are unchanged or increase the weight of.
4.2 results: in 53 routine patients, cure 15 examples (28.3%), 22 examples that take a turn for the better (41.5%), effective 13 examples (24.5%), 3 examples (5.7%) that do not heal, total effective rate is 94.3%.
5, model case
5.1 relatives, female, 42 years old, the enlargement of patient's thyroid I degree, 90 times/min of heart rate, nervous not aobvious, red tongue, thready and rapid pulse.Thyroid B ultrasonic: bilateral thyromegaly.First merit: TT3:1.23 μ g/mL, TT4:62.9 μ g/mL, TSH:8.51nIu/mL, FT3:2.10pg/mL, FT4:0.57ng/dL; TGAb:52.74u/mL, TPOAb:> 1000.00u/mL.Take the Chinese medicine composition that the present invention treats chronic lymphocytic thyroiditis and treat, treat after 2 courses for the treatment of, occasionally have cough and expectoration, the few color of expectorant is white, has palpitation, without fever with aversion to cold, without hectic fever night sweat without uncomfortable in chest.Check first merit is shown: TMAb: 226.54U/mL, and tongue is partially red, and thready pulse continues to take 2 courses for the treatment of, recovery from illness.
5.2 grandsons, female, 37 years old, throat discomfort, vexed, weak, inappetence, defecation is not smooth, a line on the 2nd.The enlargement of bilateral thyroid II degree, matter is soft, without touching a tender spot.Light red tongue, greasy and thin fur, thready pulse.Thyroid B ultrasonic: bilateral thyroid diffusivity increases.First merit: TT3:1.46 μ g/mL, TT4:47.1ng/mL, TSH:39.26nIu/mL, FT3:2.09pg/mL, FT4:0.39ng/dL, TGAb:439.94u/mL, TPOAb:811.31u/mL.Taken the Chinese medicine composition that the present invention treats chronic lymphocytic thyroiditis, after 2 courses for the treatment of, all diseases of goiter are all improved.Check thyroid function has been recovered normally, and TGAb and TPOAb decline to some extent.Continue to take 2 courses for the treatment of, it is normal that each index is recovered, and disease obtains recovery from illness.
The specific embodiment
Below in conjunction with embodiment, the present invention is further illustrated, and following this embodiment does not only limit the present invention for the present invention is described.
Embodiment 1, a kind of Chinese medicine composition for the treatment of chronic lymphocytic thyroiditis, it is to be made by following raw material medicaments: marigold flower 40g, thorn youth fruit 30g, popcorn 30g, Flos Plumeriae Acutifoliae 30g, cutter ash tree 20g, Fructus Citri tangerinae core 20g, Rhizoma Pinelliae 10g, Flos Inulae 20g, Drymoglossum Herba Drymoglossi 10g, Cortex Dictamni 8g, anistree 8g, Radix Kadsurae longipedunculatae 8g.
Embodiment 2, a kind of Chinese medicine composition for the treatment of chronic lymphocytic thyroiditis, it is to be made by following raw material medicaments: marigold flower 55g, thorn youth fruit 40g, popcorn 40g, Flos Plumeriae Acutifoliae 40g, cutter ash tree 25g, Fructus Citri tangerinae core 25g, Rhizoma Pinelliae 15g, Flos Inulae 25g, Drymoglossum Herba Drymoglossi 15g, Cortex Dictamni 12g, anistree 12g, Radix Kadsurae longipedunculatae 10g.
Embodiment 3, a kind of Chinese medicine composition for the treatment of chronic lymphocytic thyroiditis, it is to be made by following raw material medicaments: marigold flower 70g, thorn youth fruit 50g, popcorn 50g, Flos Plumeriae Acutifoliae 50g, cutter ash tree 30g, Fructus Citri tangerinae core 30g, Rhizoma Pinelliae 20g, Flos Inulae 30g, Drymoglossum Herba Drymoglossi 20g, Cortex Dictamni 15g, anistree 15g, Radix Kadsurae longipedunculatae 15g.
Claims (2)
1. treat a Chinese medicine composition for chronic lymphocytic thyroiditis, it is characterized in that being made by following raw material medicaments:
Marigold flower 40-70 part, thorn youth fruit 30-50 part, popcorn 30-50 part, Flos Plumeriae Acutifoliae 30-50 part, cutter ash tree 20-30 part, Fructus Citri tangerinae core 20-30 part, Rhizoma Pinelliae 10-20 part, Flos Inulae 20-30 part, Drymoglossum Herba Drymoglossi 10-20 part, Cortex Dictamni 8-15 part, anistree 8-15 part, Radix Kadsurae longipedunculatae 8-15 part.
2. Chinese medicine composition according to claim 1, is characterized in that being made by following raw material medicaments:
55 parts of marigold flowers, 40 parts of thorn youth fruits, 40 parts of popcorn, 40 parts of Flos Plumeriae Acutifoliaes, 25 parts of cutter ash trees, 25 parts of Fructus Citri tangerinae cores, 15 parts of the Rhizoma Pinelliaes, 25 parts of Flos Inulaes, 15 parts of Drymoglossum Herba Drymoglossis, 12 parts of Cortex Dictamni, anistree 12 parts, 10 parts of Radix Kadsurae longipedunculataes.
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| CN105168530A (en) * | 2015-10-29 | 2015-12-23 | 张冬 | Traditional Chinese medicine for treating thyroiditis and preparing method thereof |
| CN105381418A (en) * | 2015-12-26 | 2016-03-09 | 青岛昌安达药业有限公司 | Traditional Chinese medicine preparation for treating hashimoto thyroiditis |
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