CN106474215A - A kind of relieving cough and reducing sputum composition and preparation method thereof - Google Patents
A kind of relieving cough and reducing sputum composition and preparation method thereof Download PDFInfo
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- A61K35/644—Beeswax; Propolis; Royal jelly; Honey
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
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Abstract
The present invention discloses a kind of relieving cough and reducing sputum composition, is mainly made up of the raw material of following weight portion：10 25 parts of pennywort, 15 25 parts of loquat flower, 26 parts of pepper, 30 50 parts of egg, 10 15 parts of honey.The invention also discloses the preparation method of the relieving cough and reducing sputum composition soft extracts.The present composition effectively plays the effect of moistening lung, cough-relieving, resolving sputum, the respiratory infection diseases caused for coughing, catching a cold etc., such as cough, the auxiliary treatment of flu, cough and asthma, bronchitis, pulmonary tuberculosis etc., effect is significant, safety non-toxic, is particularly well-suited to the weaker old man of chronic cough, the patient of prolonged illness or body, child.
Description
Technical field
The invention belongs to technical field of health care food, and in particular to a kind of relieving cough and reducing sputum composition and preparation method thereof.
Background technology
Cough is to discharge respiratory secretions or foreign matter and a kind of body defenses reflex action for making, although favourable
One side, but chronic cough can cause hemorrhage from respiratory tract, bronchitis.Cough no matter men and women, old and young, can all occur throughout the year,
Especially easily sent out when converting in season or weather with elderly and infirm.Cough has bottleneck throat itch, discomfort, rough abundant expectoration, breathing often
The symptom such as not smooth, has a strong impact on rest, the life of people.
Chinese medicine is the product of the distinctive traditional Chinese medical theory of China and practice, and aboundresources is with a long history, is that the mankind earliest should
Natural organic substance, has the two-way function of nutrition and treatment, and pathology of the traditional Chinese medicine to comprehensive illness of coughing concurrently
The interpretation of the cause, onset and process of an illness has obvious advantage in terms of having more deep understanding, curative effect.Prior art is treated using Chinese medicine and traditional Chinese medical theory
Cough also has more research, there is not yet pennywort, loquat flower, pepper, honey, the report of egg composition.
(1) pennywort：For samphire pennywort Hydrocotyle sibthorpioides Lamarck, Hydrocotyle sibthorpioides lam.Var.Batvachium(Hand.- Mazz.) et shan
The complete stool of HydrocotylesibthorpioidesLam.var.batrachium dry herb.【Indication】Heat-clearing solution
Poison, removing dampness through diuresis and removing jaundice, cough-relieving, dispersing swelling and dissipating binds.For jaundice with damp-heat pathogen, cough, pertussis, abscess of throat, hot eyes cloudiness, gonorrhoea are wet
Rash, herpes zoster, sore swollen toxin, beat the stasis of blood swell.
(2) loquat flower：Drying for rosaceous plant loquat Eriobotrya jaPon.ica (Thunb.) I, indl.
Flower.【Function with cure mainly】Heat-clearing, dissipates wind.For cold, have a headache, thin nasal discharge.
(3) pepper：Drying closely ripe or ripening fruits for Piperaceae plant pepper Piper nigrum L..【Function with
Cure mainly】Warming spleen and stomach for dispelling cold, lower gas, dissolving phlegm.Stomachache is had loose bowels, poor appetite, epilepsy abundant expectoration.
(4) honey：For apidae insect apis cerana Apis ceranaFabricius or apis mellifera Linnaeus Apis
The honey made by melliferaLinnaeus.【Function with cure mainly】Bowl spares, moisturizes, pain relieving, removing toxic substances；External application myogenic sore.For gastral cavity
The empty pain of abdomen, dryness of the lung dry cough, dry constipation of intestines, solution Aconitum medicine poison；Control outward sore not hold back, scald.
Content of the invention
It is an object of the invention to provide a kind of relieving cough and reducing sputum composition, said composition energy moistening lung, regulating qi-flowing for harmonizing stomach, cough-relieving
Phlegm, application effect are good.
The present invention takes technical scheme below:
A kind of relieving cough and reducing sputum composition, is mainly made up of the raw material of following weight portion：Pennywort 10-25 part, loquat flower 15-
25 parts, pepper 2-6 part, egg 30-50 part, honey 10-15 part.
Preferably, the above relieving cough and reducing sputum composition, is mainly made up of the raw material of following weight portion：16 parts of pennywort,
20 parts of loquat flower, 3 parts of pepper, 40 parts of egg, 13 parts of honey.
The above is relieving cough and reducing sputum composition, can be prepared into acceptable any preparation, be preferably prepared to powder, granule
(electuary), pill, tablet, capsule, decoction, cream, mixture (including oral liquid), syrup, tea-drinking etc., are wherein most preferably preferably made
Cream.
The preparation method of more than one relieving cough and reducing sputum composition paste, comprises the following steps：
S1：Raw material is weighed by following weight portion：Pennywort 10-25 part, loquat flower 15-25 part, pepper 2-6 part, egg 30-
50 parts, honey 10-15 part；
S2：Take pennywort, loquat flower, plus 6-8 times amount water, heating and refluxing extraction 2-3 time, each 1-3 hour, filtration, conjunction
And filtrate, filtration, concentrate, clear cream is obtained, is let cool, 2 times amount of ethanol is added, stir, standing 24-48 hour, filtration, concentrate, obtain thick
Cream；
S3：Pepper is taken, is crushed, 80-200 mesh sieve is crossed, obtains pepper powder；
S4：Egg is removed shell breaking, egg white and yolk is stirred evenly, clear cream, pepper powder, honey is added, is added and accounts for gross weight
The Sodium Benzoate of 0.5-1%, mixes, cooks, obtain final product.
The preparation method of composition paste that the above is relieving cough and reducing sputum, step S1 preferably weigh original by following weight portion
Material：16 parts of pennywort, 20 parts of loquat flower, 3 parts of pepper, 40 parts of egg, 13 parts of honey.
The preparation method of the above relieving cough and reducing sputum composition paste, clear cream described in step S2 are preferably 80 DEG C
When relative density for 1.10-1.15 clear cream.
The preparation method of composition paste that the above is relieving cough and reducing sputum, the thick paste that step S2 is obtained are preferably 60 DEG C of phases
It is 1.20～1.25 thick paste to density；
The preparation method of composition paste that the above is relieving cough and reducing sputum, the concentration of the step S2 ethanol are preferably 90%.
The application of the above is relieving cough and reducing sputum composition, the composition such as are used for can be used for coughing, catch a cold the exhaling of causing
Inhale road to catch, such as cough, the auxiliary treatment of flu, cough and asthma, bronchitis, pulmonary tuberculosis etc., are particularly well-suited to chronic cough, prolonged illness
Patient or the weaker old man of body, child.
The beneficial effect that the present invention is obtained：
1. the present invention, is shared with loquat flower, pepper in conjunction with medication experience among the people with the peculiar Chinese medicine pennywort in Guangxi, then
Add the honey for supplementing the nutrition of needed by human body, the egg of enhance immunity compound and having moistening lung effect concurrently, effectively play moistening lung,
Cough-relieving, the effect of resolving sputum, are formulated with modern scientific theory, and the composition being combined into causes for coughing, catching a cold etc.
Respiratory infection diseases, such as cough, the auxiliary treatment of flu, cough and asthma, bronchitis, pulmonary tuberculosis etc., efficient up to 97%, peace
Completely without toxic and side effect, the weaker old man of chronic cough, the patient of prolonged illness or body, child is particularly well-suited to.
2. the relieving cough and reducing sputum composite formula science of the present invention, preparation process is simple, low cost, application effect are good, it is easy to
Realize industrialization.
3. the relieving cough and reducing sputum composition paste of the present invention, commonly uses food materials pepper using being directly used as medicine after crushing in preparation method,
The loss of pepper effective active composition can be reduced.Using egg mesolecithal, egg white, after cooking, become paste, containing abundant battalion
Foster material, fragrant and sweet good to eat, the difficult child that takes medicine is particularly well-suited to, drug compliance is good.
Specific embodiment
For ease of more fully understanding the present invention, it is illustrated by following examples, these embodiments belong to the present invention's
Protection domain, but do not limit the scope of the invention.
First, the preparation of relieving cough and reducing sputum composition paste
Embodiment 1
A kind of preparation method of relieving cough and reducing sputum composition paste, comprises the following steps：
S1：Raw material is weighed by following weight kg：Pennywort 10kg, loquat flower 15kg, pepper 2kg, egg 30kg, honey
10kg；
S2：Take pennywort, loquat flower, plus 6 times amount water, heating and refluxing extraction 2 times, 1 hour every time, filtration, merging filtrate,
Filtration, concentrates, and when obtaining 80 DEG C, relative density is 1.10 clear cream, lets cool, and adds 95% ethanol, 2 times amount, and stirring, standing 24 are little
When, filtration, when being concentrated into 60 DEG C, relative density is 1.20 thick paste；
S3：Pepper is taken, is crushed, 80 mesh sieves are crossed, obtains pepper powder；
S4：Egg is removed shell breaking, egg white and yolk is stirred evenly, clear cream, pepper powder, honey is added, is added and accounts for gross weight
0.5% Sodium Benzoate, mixes, cooks, obtain final product.
Embodiment 2
A kind of preparation method of relieving cough and reducing sputum composition paste, comprises the following steps：
S1：Raw material is weighed by following weight kg：Pennywort 25kg, loquat flower 25kg, pepper 6kg, egg 50kg, honey
15kg；
S2：Take pennywort, loquat flower, plus 8 times amount water, heating and refluxing extraction 2 times, 3 hours every time, filtration, merging filtrate,
Filtration, concentrates, and when obtaining 80 DEG C, relative density is 1.15 clear cream, lets cool, and adds 95% ethanol, 2 times amount, and stirring, standing 48 are little
When, filtration, when being concentrated into 60 DEG C, relative density is 1.25 thick paste；
S3：Pepper is taken, is crushed, 200 mesh sieves are crossed, obtains pepper powder；
S4：Egg is removed shell breaking, egg white and yolk is stirred evenly, clear cream, pepper powder, honey is added, is added and accounts for gross weight
1% Sodium Benzoate, mixes, cooks, obtain final product.
Embodiment 3
A kind of preparation method of relieving cough and reducing sputum composition paste, comprises the following steps：
S1：Raw material is weighed by following weight kg：Pennywort 16kg, loquat flower 20kg, pepper 3kg, egg 40kg, honey
13kg；
S2：Take pennywort, loquat flower, plus 7 times amount water, heating and refluxing extraction 3 times, 2 hours every time, filtration, merging filtrate,
Filtration, concentrates, and when obtaining 80 DEG C, relative density is 1.13 clear cream, lets cool, and adds 90% ethanol, 2 times amount, and stirring, standing 24 are little
When, filtration, when being concentrated into 60 DEG C, relative density is 1.22 thick paste；
S3：Pepper is taken, is crushed, 100 mesh sieves are crossed, obtains pepper powder；
S4：Egg is removed shell breaking, egg white and yolk is stirred evenly, clear cream, pepper powder, honey is added, is added and accounts for gross weight
0.8% Sodium Benzoate, mixes, cooks, obtain final product.
Embodiment 4
A kind of preparation method of relieving cough and reducing sputum composition paste, comprises the following steps：
S1：Raw material is weighed by following weight kg：Pennywort 22kg, loquat flower 22kg, pepper 5kg, egg 50kg, honey
10kg；
S2：Take pennywort, loquat flower, plus 8 times amount water, heating and refluxing extraction 2 times, 2 hours every time, filtration, merging filtrate,
Filtration, concentrates, and when obtaining 80 DEG C, relative density is 1.20 clear cream, lets cool, and adds 95% ethanol, 2 times amount, and stirring, standing 48 are little
When, filtration, when being concentrated into 60 DEG C, relative density is 1.30 thick paste；
S3：Pepper is taken, is crushed, 100 mesh sieves are crossed, obtains pepper powder；
S4：Egg is removed shell breaking, egg white and yolk is stirred evenly, clear cream, pepper powder, honey is added, is added and accounts for gross weight
1.0% Sodium Benzoate, mixes, cooks, obtain final product.
2nd, application test
1. subjects selection standard
Primary symptom：Cough, nothing phlegm or expectoration；
Secondary disease：Pharynx is itched or pain；Dry throat；Nasal obstruction；Runny nose；Out of breath pant；Bronchitis；Pneumonia；Pulmonary tuberculosis；Tongue thin white or
Yellow；Floating and tense pulse or cunning.
Possess 2 in above primary symptom and secondary disease, the age is in 3-80 year person, you can.
2. application scheme
Test group：By above-mentioned 3 sample of embodiment for preparing, for above-mentioned subjects.Oral, more than 16 years old, every time 2
Spoon (20g), 3 times a day；8-15 year, 1.5 spoonfuls (15g) every time, 3 times a day；3-7 year, 1 spoonful (10g) every time, 3 times a day.Take
Time：5 day are continuously taken.
Control group：Chuanbei pipa syrup, is administered orally, more than 10 years old each 10ml, and 3 times a day；3-10 year, each 5ml, daily
3 times.Time of Administration：5 day are continuously taken.
3. effect criterion
Recovery from illness：Cough symptom, sign disappear or basic disappearance, and integration reduces more than 95%.
Effective：Cough symptom, sign are obviously improved, and integration is reduced between 70%-94%.
Effectively：Cough symptom, sign all take a favorable turn, and integration is reduced in 30%-<69%.
Invalid：Cough symptom is not improved, and very then increases, and integration is reduced<30%.
Computing formula is：[integration before (integrating after integration-treatment before treatment) ÷ treatment] × 100%
4. result is applied
By relieving cough and reducing sputum for present invention composition paste and the chuanbei pipa syrup of certain company's production commercially available, 105 were once applied to
Volunteer (man 52, female 53, wherein：3-15 year 26,16-50 year 60；51-80 year 29).The results detailed in Table 1.
1 application effect of products investigation result table of table
Application test result shows：Using the relieving cough and reducing sputum composition of the present invention, cough recovery from illness 76%, efficient reach 97%,
Without bad reaction occur, its application effect be better than control group, illustrate the present invention to cough have good effect, with moistening lung,
Cough-relieving, the effect of resolving sputum, the respiratory infection diseases for causing such as can be used to coughing, catch a cold, such as cough, flu, cough and asthma, bronchus
The auxiliary treatment of inflammation, pulmonary tuberculosis etc., safe without toxic side effect, it is particularly well-suited to chronic cough, the patient of prolonged illness or body weaker
Old man, child.
3rd, typical case
In addition to above-mentioned application test, also the embodiment 1-4 sample of relieving cough and reducing sputum for present invention composition paste is used for other will
Hope person, all obtains good result, is several typical cases below：
Case 1：Poplar ××, man, 35 years old, cardinal symptom was：Cough, dry cough without phlegm, nasal obstruction, runny nose, tongue are thin white, floating pulse
Tightly.The cream (embodiment 1) that the relieving cough and reducing sputum composition of the present invention is made is taken, every time 2 spoonfuls (20g), 3 times a day, 3 is serve on, disease
Shape is eliminated, recovery from illness.
Case 2：××, man, 75 years old, chronic bronchitis patient, weather turned cold outbreak, cough, and expectoration, pharynx are itched, gas
Short pant.The cream (embodiment 3) that the relieving cough and reducing sputum composition of the present invention is made is taken, every time 2 spoonfuls (20g), 3 times a day, serve on 5
Day, symptom mitigation, then continuously take 5, recovery from illness, nothing recurrence is paid a return visit after 1 year.
Case 3：Beam ××, female, 3 years old, with cough, expectoration, pharyngeal portion flare as cardinal symptom.Take the present invention relieving cough and reducing sputum
The cream (embodiment 4) that composition is made, 1 spoonful (10g) every time, 3 times a day, and after 2 days, cough symptom mitigates, and expectoration amount is reduced, then
3 are serve on, symptom eliminates, recovery from illness.
Above-described be only the present invention preferred embodiment, it is noted that for the ordinary skill people of this area
For member, without departing from the concept of the premise of the invention, some deformation and improvement can also be made, these belong to this
Bright protection domain.
Claims (10)
1. a kind of relieving cough and reducing sputum composition, it is characterised in that be mainly made up of the raw material of following weight portion：Pennywort 10-25 part,
Loquat flower 15-25 part, pepper 2-6 part, egg 30-50 part, honey 10-15 part.
2. relieving cough and reducing sputum composition as claimed in claim 1, it is characterised in that be mainly made up of the raw material of following weight portion：My god
16 parts of coriandrum, 20 parts of loquat flower, 3 parts of pepper, 40 parts of egg, 13 parts of honey.
3. relieving cough and reducing sputum composition as claimed in claim 1, it is characterised in that the composition makes powder, granule, ball
Agent, tablet, capsule, decoction, cream, mixture, oral liquid or syrup.
4. relieving cough and reducing sputum composition as claimed in claim 1, it is characterised in that the composition makes cream.
5. a kind of preparation method of relieving cough and reducing sputum as claimed in claim 4 composition paste, it is characterised in that comprise the following steps：
S1：Raw material is weighed by following weight portion：Pennywort 10-25 part, loquat flower 15-25 part, pepper 2-6 part, egg 30-50
Part, honey 10-15 part；
S2：Take pennywort, loquat flower, plus 6-8 times amount water, heating and refluxing extraction 2-3 time, each 1-3 hour, filtration, merging filter
Liquid, filtration, concentrate, clear cream is obtained, is let cool, 2 times amount of ethanol is added, stir, standing 24-48 hour, filtration, concentrate, obtain thick paste；
S3：Pepper is taken, is crushed, 80-200 mesh sieve is crossed, obtains pepper powder；
S4：Egg is removed shell breaking, egg white and yolk is stirred evenly, clear cream, pepper powder, honey is added, is added and accounts for gross weight 0.5-
1% Sodium Benzoate, mixes, cooks, obtain final product.
6. the preparation method of relieving cough and reducing sputum composition paste as claimed in claim 5, it is characterised in that step S1 is by following heavy
Amount part weighs raw material：16 parts of pennywort, 20 parts of loquat flower, 3 parts of pepper, 40 parts of egg, 13 parts of honey.
7. the preparation method of the relieving cough and reducing sputum composition paste as claimed in claim 5, it is characterised in that institute in step S2
It is the clear cream of 1.10-1.15 to state relative density when clear cream is 80 DEG C.
8. the preparation method of relieving cough and reducing sputum composition paste as claimed in claim 5, it is characterised in that it is thick that step S2 is obtained
When cream is 60 DEG C, relative density is 1.20～1.25 thick paste.
9. the preparation method of relieving cough and reducing sputum composition paste as claimed in claim 5, it is characterised in that the step S2 ethanol dense
Spend for 90%.
10. a kind of application of relieving cough and reducing sputum composition, it is characterised in that the composition is used for causing for coughing, catching a cold etc.
Respiratory infection diseases, such as cough, the auxiliary treatment of flu, cough and asthma, bronchitis, pulmonary tuberculosis etc..
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| Application Number | Priority Date | Filing Date | Title |
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| CN201611269953.3A CN106474215A (en) | 2016-12-31 | 2016-12-31 | A kind of relieving cough and reducing sputum composition and preparation method thereof |
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| CN201611269953.3A CN106474215A (en) | 2016-12-31 | 2016-12-31 | A kind of relieving cough and reducing sputum composition and preparation method thereof |
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| CN106474215A true CN106474215A (en) | 2017-03-08 |
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Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103550473A (en) * | 2013-10-29 | 2014-02-05 | 王祖阳 | Traditional Chinese medicine formula beneficial to relieving cough and reducing sputum |
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2016
- 2016-12-31 CN CN201611269953.3A patent/CN106474215A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103550473A (en) * | 2013-10-29 | 2014-02-05 | 王祖阳 | Traditional Chinese medicine formula beneficial to relieving cough and reducing sputum |
Non-Patent Citations (4)
| Title |
|---|
| 张兆旺: "《中药药剂学》", 31 July 2016, 中国中医药出版社 * |
| 李建松: "鲜天胡荽治疗干咳效好", 《新中医》 * |
| 杨建峰: "《中草药大典》", 31 January 2015, 江西科学技术出版社 * |
| 肖永庆: "《中华医学百科全书 中药炮制学》", 30 November 2016, 中国协和医科大学出版社 * |
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Application publication date: 20170308 |