CN106456975B - 用于电神经调制的导管和导管系统 - Google Patents

用于电神经调制的导管和导管系统 Download PDF

Info

Publication number
CN106456975B
CN106456975B CN201580031878.4A CN201580031878A CN106456975B CN 106456975 B CN106456975 B CN 106456975B CN 201580031878 A CN201580031878 A CN 201580031878A CN 106456975 B CN106456975 B CN 106456975B
Authority
CN
China
Prior art keywords
catheter
elongated
elongate
stimulation
pulmonary artery
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201580031878.4A
Other languages
English (en)
Chinese (zh)
Other versions
CN106456975A (zh
Inventor
S·D·格德克
S·L·瓦尔德豪泽
C·L·尤腾努尔
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cardionomic Inc
Original Assignee
Cardionomic Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cardionomic Inc filed Critical Cardionomic Inc
Priority to CN202010802494.0A priority Critical patent/CN111790047B/zh
Publication of CN106456975A publication Critical patent/CN106456975A/zh
Application granted granted Critical
Publication of CN106456975B publication Critical patent/CN106456975B/zh
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/05Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/056Transvascular endocardial electrode systems
    • A61N1/057Anchoring means; Means for fixing the head inside the heart
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36053Implantable neurostimulators for stimulating central or peripheral nerve system adapted for vagal stimulation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/10Balloon catheters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0472Structure-related aspects
    • A61N1/0476Array electrodes (including any electrode arrangement with more than one electrode for at least one of the polarities)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/05Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/056Transvascular endocardial electrode systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36114Cardiac control, e.g. by vagal stimulation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Cardiology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Vascular Medicine (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Electrotherapy Devices (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
CN201580031878.4A 2014-05-22 2015-05-21 用于电神经调制的导管和导管系统 Active CN106456975B (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202010802494.0A CN111790047B (zh) 2014-05-22 2015-05-21 用于电神经调制的导管和导管系统

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462001729P 2014-05-22 2014-05-22
US62/001,729 2014-05-22
PCT/US2015/031960 WO2015179634A2 (en) 2014-05-22 2015-05-21 Catheter and catheter system for electrical neuromodulation

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN202010802494.0A Division CN111790047B (zh) 2014-05-22 2015-05-21 用于电神经调制的导管和导管系统

Publications (2)

Publication Number Publication Date
CN106456975A CN106456975A (zh) 2017-02-22
CN106456975B true CN106456975B (zh) 2020-09-04

Family

ID=53284616

Family Applications (2)

Application Number Title Priority Date Filing Date
CN201580031878.4A Active CN106456975B (zh) 2014-05-22 2015-05-21 用于电神经调制的导管和导管系统
CN202010802494.0A Active CN111790047B (zh) 2014-05-22 2015-05-21 用于电神经调制的导管和导管系统

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN202010802494.0A Active CN111790047B (zh) 2014-05-22 2015-05-21 用于电神经调制的导管和导管系统

Country Status (8)

Country Link
US (2) US10576273B2 (enExample)
EP (1) EP3145583B1 (enExample)
JP (2) JP6580068B2 (enExample)
CN (2) CN106456975B (enExample)
AU (1) AU2015264121B2 (enExample)
CA (1) CA2946791C (enExample)
SG (2) SG11201608878SA (enExample)
WO (1) WO2015179634A2 (enExample)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008070189A2 (en) 2006-12-06 2008-06-12 The Cleveland Clinic Foundation Method and system for treating acute heart failure by neuromodulation
US8906011B2 (en) 2007-11-16 2014-12-09 Kardium Inc. Medical device for use in bodily lumens, for example an atrium
US9486273B2 (en) 2011-01-21 2016-11-08 Kardium Inc. High-density electrode-based medical device system
CA2764494A1 (en) 2011-01-21 2012-07-21 Kardium Inc. Enhanced medical device for use in bodily cavities, for example an atrium
US9452016B2 (en) 2011-01-21 2016-09-27 Kardium Inc. Catheter system
US11259867B2 (en) 2011-01-21 2022-03-01 Kardium Inc. High-density electrode-based medical device system
CN106456975B (zh) 2014-05-22 2020-09-04 卡迪诺米克公司 用于电神经调制的导管和导管系统
AU2015315658B2 (en) 2014-09-08 2019-05-23 CARDIONOMIC, Inc. Catheter and electrode systems for electrical neuromodulation
EP3194017A1 (en) 2014-09-08 2017-07-26 Cardionomic, Inc. Methods for electrical neuromodulation of the heart
EP3610917A1 (en) 2015-01-05 2020-02-19 Cardionomic, Inc. Cardiac modulation facilitation methods and systems
SG11201807446UA (en) 2016-03-09 2018-09-27 Cardionomic Inc Cardiac contractility neurostimulation systems and methods
EP3664703A4 (en) * 2017-09-13 2021-05-12 Cardionomic, Inc. Neurostimulation systems and methods for affecting cardiac contractility
EP4606336A2 (en) 2018-08-13 2025-08-27 Cardionomic, Inc. Systems and methods for affecting cardiac contractility and/or relaxation
CN114040704A (zh) 2019-05-06 2022-02-11 卡迪诺米克公司 用于在电神经调节期间对生理信号去噪的系统和方法
WO2021060494A1 (ja) * 2019-09-27 2021-04-01 テルモ株式会社 治療デバイスおよび治療方法
CN116328178A (zh) * 2021-12-16 2023-06-27 微创投资控股有限公司 输送系统、人工耳蜗植入系统、控制方法及存储介质
WO2023161287A1 (en) * 2022-02-28 2023-08-31 Medtronic Ireland Manufacturing Unlimited Company Neuromodulation catheter
CN115154852B (zh) * 2022-08-12 2023-07-14 深圳市赛禾医疗技术有限公司 锚定球囊导管
FR3149763B1 (fr) * 2023-06-16 2025-07-18 Electroducer Cathéter de stimulation trans-vasculaire et de dénervation d’une partie d’un système nerveux autonome d’un corps humain, notamment de stimulation trans-vasculaire nerveuse rénale ou de stimulation du glomus carotidien.
FR3149762B1 (fr) * 2023-06-16 2025-08-01 Electroducer Ensemble à fil-guide bipolaire, de stimulation trans-vasculaire d’une partie d’un système nerveux autonome d’un corps humain, notamment de stimulation trans-vasculaire nerveuse rénale ou de stimulation du glomus carotidien.

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070135875A1 (en) * 2002-04-08 2007-06-14 Ardian, Inc. Methods and apparatus for thermally-induced renal neuromodulation
WO2012149511A2 (en) * 2011-04-28 2012-11-01 Synecor Llc Neuromodulation systems and methods for treating acute heart failure syndromes
CN103239799A (zh) * 2013-05-21 2013-08-14 重庆绿色智能技术研究院 用于膀胱功能性电刺激的电极

Family Cites Families (361)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5190546A (en) 1983-10-14 1993-03-02 Raychem Corporation Medical devices incorporating SIM alloy elements
US5067957A (en) 1983-10-14 1991-11-26 Raychem Corporation Method of inserting medical devices incorporating SIM alloy elements
US4718423A (en) 1986-10-17 1988-01-12 Spectramed, Inc. Multiple-function cardiovascular catheter system with very high lumenal efficiency and no crossovers
US5365926A (en) 1986-11-14 1994-11-22 Desai Jawahar M Catheter for mapping and ablation and method therefor
US4947866A (en) 1988-02-16 1990-08-14 Medtronic, Inc. Medical electrical lead
US4950227A (en) 1988-11-07 1990-08-21 Boston Scientific Corporation Stent delivery system
US5224491A (en) 1991-01-07 1993-07-06 Medtronic, Inc. Implantable electrode for location within a blood vessel
US5345936A (en) 1991-02-15 1994-09-13 Cardiac Pathways Corporation Apparatus with basket assembly for endocardial mapping
US5156154A (en) 1991-03-08 1992-10-20 Telectronics Pacing Systems, Inc. Monitoring the hemodynamic state of a patient from measurements of myocardial contractility using doppler ultrasound techniques
US5197978B1 (en) 1991-04-26 1996-05-28 Advanced Coronary Tech Removable heat-recoverable tissue supporting device
US5213098A (en) 1991-07-26 1993-05-25 Medtronic, Inc. Post-extrasystolic potentiation stimulation with physiologic sensor feedback
US5259387A (en) 1991-09-09 1993-11-09 Quinton Instrument Company ECG muscle artifact filter system
DE69332950T2 (de) 1992-03-31 2004-05-13 Boston Scientific Corp., Natick Blutgefässfilter
US5782239A (en) 1992-06-30 1998-07-21 Cordis Webster, Inc. Unique electrode configurations for cardiovascular electrode catheter with built-in deflection method and central puller wire
US5336244A (en) 1992-10-07 1994-08-09 Medtronic, Inc. Temperature sensor based capture detection for a pacer
US5383852A (en) * 1992-12-04 1995-01-24 C. R. Bard, Inc. Catheter with independent proximal and distal control
US5462527A (en) * 1993-06-29 1995-10-31 C.R. Bard, Inc. Actuator for use with steerable catheter
US5611777A (en) * 1993-05-14 1997-03-18 C.R. Bard, Inc. Steerable electrode catheter
IL116699A (en) 1996-01-08 2001-09-13 Biosense Ltd Method of building a heart map
US5431649A (en) 1993-08-27 1995-07-11 Medtronic, Inc. Method and apparatus for R-F ablation
WO1995010978A1 (en) 1993-10-19 1995-04-27 Ep Technologies, Inc. Segmented electrode assemblies for ablation of tissue
JPH07178176A (ja) 1993-12-24 1995-07-18 Terumo Corp カテーテル
US6216043B1 (en) * 1994-03-04 2001-04-10 Ep Technologies, Inc. Asymmetric multiple electrode support structures
US5968040A (en) * 1994-03-04 1999-10-19 Ep Technologies, Inc. Systems and methods using asymmetric multiple electrode arrays
US5423881A (en) 1994-03-14 1995-06-13 Medtronic, Inc. Medical electrical lead
US5598848A (en) 1994-03-31 1997-02-04 Ep Technologies, Inc. Systems and methods for positioning multiple electrode structures in electrical contact with the myocardium
US5564434A (en) 1995-02-27 1996-10-15 Medtronic, Inc. Implantable capacitive absolute pressure and temperature sensor
US6059810A (en) 1995-05-10 2000-05-09 Scimed Life Systems, Inc. Endovascular stent and method
US6363279B1 (en) 1996-01-08 2002-03-26 Impulse Dynamics N.V. Electrical muscle controller
IL148949A0 (en) 1996-01-08 2002-11-10 Impulse Dynamics Nv Electrical muscle controller
US8321013B2 (en) 1996-01-08 2012-11-27 Impulse Dynamics, N.V. Electrical muscle controller and pacing with hemodynamic enhancement
IL119261A0 (en) 1996-09-17 1996-12-05 New Technologies Sa Ysy Ltd Electrical muscle controller
JP4175662B2 (ja) 1996-01-08 2008-11-05 インパルス ダイナミクス エヌ.ヴイ. 電気的筋肉制御装置
IL125424A0 (en) 1998-07-20 1999-03-12 New Technologies Sa Ysy Ltd Pacing with hemodynamic enhancement
US9289618B1 (en) 1996-01-08 2016-03-22 Impulse Dynamics Nv Electrical muscle controller
US7167748B2 (en) 1996-01-08 2007-01-23 Impulse Dynamics Nv Electrical muscle controller
US8825152B2 (en) 1996-01-08 2014-09-02 Impulse Dynamics, N.V. Modulation of intracellular calcium concentration using non-excitatory electrical signals applied to the tissue
US6415178B1 (en) 1996-09-16 2002-07-02 Impulse Dynamics N.V. Fencing of cardiac muscles
US5853411A (en) 1996-01-19 1998-12-29 Ep Technologies, Inc. Enhanced electrical connections for electrode structures
WO1997037720A1 (en) 1996-04-04 1997-10-16 Medtronic, Inc. Living tissue stimulation and recording techniques
FR2796562B1 (fr) 1996-04-04 2005-06-24 Medtronic Inc Techniques de stimulation d'un tissu vivant et d'enregistrement avec commande locale de sites actifs
US6006134A (en) 1998-04-30 1999-12-21 Medtronic, Inc. Method and device for electronically controlling the beating of a heart using venous electrical stimulation of nerve fibers
US5711316A (en) 1996-04-30 1998-01-27 Medtronic, Inc. Method of treating movement disorders by brain infusion
US6463324B1 (en) 1996-09-16 2002-10-08 Impulse Dynamics N. V. Cardiac output enhanced pacemaker
ZA976112B (en) 1996-09-16 1998-02-10 New Technologies Sa Ysy Ltd Apparatus and method for controlling the contractility of muscles.
AU3356897A (en) 1996-09-16 1998-04-02 Impluse Dynamics (Israel) Ltd. Drug-device combination for controlling the contractility of muscles
US5755766A (en) 1997-01-24 1998-05-26 Cardiac Pacemakers, Inc. Open-ended intravenous cardiac lead
US5954761A (en) 1997-03-25 1999-09-21 Intermedics Inc. Implantable endocardial lead assembly having a stent
US5948007A (en) 1997-04-30 1999-09-07 Medtronic, Inc. Dual channel implantation neurostimulation techniques
US6547788B1 (en) 1997-07-08 2003-04-15 Atrionx, Inc. Medical device with sensor cooperating with expandable member
JP4102545B2 (ja) 1997-07-16 2008-06-18 メタキュアー エヌブイ 平滑筋制御装置
US6071308A (en) 1997-10-01 2000-06-06 Boston Scientific Corporation Flexible metal wire stent
US6231516B1 (en) 1997-10-14 2001-05-15 Vacusense, Inc. Endoluminal implant with therapeutic and diagnostic capability
US6058331A (en) 1998-04-27 2000-05-02 Medtronic, Inc. Apparatus and method for treating peripheral vascular disease and organ ischemia by electrical stimulation with closed loop feedback control
US6319241B1 (en) 1998-04-30 2001-11-20 Medtronic, Inc. Techniques for positioning therapy delivery elements within a spinal cord or a brain
US6447478B1 (en) 1998-05-15 2002-09-10 Ronald S. Maynard Thin-film shape memory alloy actuators and processing methods
US6428537B1 (en) * 1998-05-22 2002-08-06 Scimed Life Systems, Inc. Electrophysiological treatment methods and apparatus employing high voltage pulse to render tissue temporarily unresponsive
US6740113B2 (en) 1998-05-29 2004-05-25 Scimed Life Systems, Inc. Balloon expandable stent with a self-expanding portion
US7198635B2 (en) 2000-10-17 2007-04-03 Asthmatx, Inc. Modification of airways by application of energy
WO1999065561A1 (en) 1998-06-19 1999-12-23 Cordis Webster, Inc. Method and apparatus for transvascular treatment of tachycardia and fibrillation
US6036697A (en) 1998-07-09 2000-03-14 Scimed Life Systems, Inc. Balloon catheter with balloon inflation at distal end of balloon
US6950689B1 (en) 1998-08-03 2005-09-27 Boston Scientific Scimed, Inc. Dynamically alterable three-dimensional graphical model of a body region
US5997563A (en) 1998-09-28 1999-12-07 Medtronic, Inc. Implantable stent having variable diameter
IL126905A0 (en) 1998-11-05 1999-09-22 Impulse Dynamics Ltd Multi-electrode catheter
AU1072100A (en) 1998-11-06 2000-05-29 Impulse Dynamics N.V. Trigger-based regulation of excitable tissue control in the heart
US6675043B1 (en) 1998-11-06 2004-01-06 Impulse Dynamics N.V. Sensor-based regulation of excitable tissue control of the heart
US6725093B1 (en) 1998-11-06 2004-04-20 Impulse Dynamics N.V. Regulation of excitable tissue control of the heart based on physiological input
US6292693B1 (en) 1998-11-06 2001-09-18 Impulse Dynamics N.V. Contractility enhancement using excitable tissue control and multi-site pacing
US6254610B1 (en) 1999-05-24 2001-07-03 Impulse Dynamics N.V. Device and method for dragging and positioning a member within a duct in a body
US6152882A (en) 1999-01-26 2000-11-28 Impulse Dynamics N.V. Apparatus and method for chronic measurement of monophasic action potentials
US6161029A (en) 1999-03-08 2000-12-12 Medtronic, Inc. Apparatus and method for fixing electrodes in a blood vessel
US6136021A (en) 1999-03-23 2000-10-24 Cardiac Pacemakers, Inc. Expandable electrode for coronary venous leads
US6263242B1 (en) 1999-03-25 2001-07-17 Impulse Dynamics N.V. Apparatus and method for timing the delivery of non-excitatory ETC signals to a heart
US6370430B1 (en) 1999-03-25 2002-04-09 Impulse Dynamics N.V. Apparatus and method for controlling the delivery of non-excitatory cardiac contractility modulating signals to a heart
US6522904B1 (en) 1999-03-30 2003-02-18 Impulse Dynamics N.V. Bipolar sensor for muscle tissue action potential duration estimation
WO2000059375A1 (en) 1999-04-05 2000-10-12 The Regents Of The University Of California Endomyocardial monophasic action potential for early detection of myocardium pathology
US6353762B1 (en) 1999-04-30 2002-03-05 Medtronic, Inc. Techniques for selective activation of neurons in the brain, spinal cord parenchyma or peripheral nerve
US6292704B1 (en) 1999-05-25 2001-09-18 Impulse Dynamics N. V. High capacitance myocardial electrodes
US6442424B1 (en) 1999-05-26 2002-08-27 Impulse Dynamics N.V. Local cardiac motion control using applied electrical signals
WO2000072918A1 (en) 1999-05-26 2000-12-07 Impulse Dynamic Nv Shockless defibrillation
US6285906B1 (en) 1999-05-26 2001-09-04 Impulse Dynamics N. V. Muscle contraction assist device
US6304777B1 (en) 1999-05-26 2001-10-16 Impulse Dynamics N.V. Induction of cardioplegia applied electrical signals
US7190997B1 (en) 1999-06-04 2007-03-13 Impulse Dynamics Nv Drug delivery device
US7092753B2 (en) 1999-06-04 2006-08-15 Impulse Dynamics Nv Drug delivery device
US7171263B2 (en) 1999-06-04 2007-01-30 Impulse Dynamics Nv Drug delivery device
US6233487B1 (en) 1999-06-08 2001-05-15 Impulse Dynamics N.V. Apparatus and method for setting the parameters of an alert window used for timing the delivery of ETC signals to a heart under varying cardiac conditions
US6223072B1 (en) 1999-06-08 2001-04-24 Impulse Dynamics N.V. Apparatus and method for collecting data useful for determining the parameters of an alert window for timing delivery of ETC signals to a heart under varying cardiac conditions
CA2376903A1 (en) 1999-06-25 2001-01-04 Emory University Devices and methods for vagus nerve stimulation
US6348045B1 (en) 1999-07-12 2002-02-19 Impulse Dynamics N.V. Catheter with distal-end engaging means
US6335538B1 (en) 1999-07-23 2002-01-01 Impulse Dynamics N.V. Electro-optically driven solid state relay system
CA2314517A1 (en) 1999-07-26 2001-01-26 Gust H. Bardy System and method for determining a reference baseline of individual patient status for use in an automated collection and analysis patient care system
US7303526B2 (en) 1999-08-09 2007-12-04 Cardiokinetix, Inc. Device for improving cardiac function
US6360126B1 (en) 1999-08-20 2002-03-19 Impulse Dynamics N.V. Apparatus and method for controlling the delivery of contractility modulating non-excitatory signals to the heart
US6360123B1 (en) 1999-08-24 2002-03-19 Impulse Dynamics N.V. Apparatus and method for determining a mechanical property of an organ or body cavity by impedance determination
US7027863B1 (en) 1999-10-25 2006-04-11 Impulse Dynamics N.V. Device for cardiac therapy
US6993385B1 (en) 1999-10-25 2006-01-31 Impulse Dynamics N.V. Cardiac contractility modulation device having anti-arrhythmic capabilities and a method of operating thereof
WO2001030445A1 (en) 1999-10-25 2001-05-03 Impulse Dynamics N.V. Cardiac contractility modulation device having anti-arrhythmic capabilities and a method of operating thereof
US6295475B1 (en) 1999-10-27 2001-09-25 Pacesetter, Inc. Single-pass atrial ventricular lead with multiple atrial ring electrodes and a selective atrial electrode adaptor for the coronary sinus region
US6662055B1 (en) 1999-12-17 2003-12-09 Impulse Dynamics Nv Multi-electrode intravascular lead
IL133592A0 (en) 1999-12-19 2001-04-30 Impulse Dynamics Ltd Fluid phase electrode lead
US6480737B1 (en) 1999-12-29 2002-11-12 Impulse Dynamics Nv Field delivery safety system using detection of atypical ECG
US20060085046A1 (en) 2000-01-20 2006-04-20 Ali Rezai Methods of treating medical conditions by transvascular neuromodulation of the autonomic nervous system
US6600953B2 (en) 2000-12-11 2003-07-29 Impulse Dynamics N.V. Acute and chronic electrical signal therapy for obesity
US7096070B1 (en) 2000-02-09 2006-08-22 Transneuronix, Inc. Medical implant device for electrostimulation using discrete micro-electrodes
US7195637B2 (en) 2000-04-18 2007-03-27 Impulse Dynamics N.V. Method and device for inserting leads into coronary veins
US6754532B1 (en) 2000-04-28 2004-06-22 Medtronic, Inc. Coronary sinus flow regulated pacing
EP1284781B1 (en) 2000-05-04 2017-10-11 Impulse Dynamics N.V. Signal delivery through the right ventricular septum
US20040215233A1 (en) 2000-06-16 2004-10-28 Magenta Medical Corporation Methods and apparatus for forming anastomotic sites
US6712831B1 (en) 2000-06-16 2004-03-30 Aaron V. Kaplan Methods and apparatus for forming anastomotic sites
US6694192B2 (en) 2000-07-06 2004-02-17 Impulse Dynamics N.V. Uterus muscle controller
US8086314B1 (en) 2000-09-27 2011-12-27 Cvrx, Inc. Devices and methods for cardiovascular reflex control
US6522926B1 (en) 2000-09-27 2003-02-18 Cvrx, Inc. Devices and methods for cardiovascular reflex control
US6850801B2 (en) 2001-09-26 2005-02-01 Cvrx, Inc. Mapping methods for cardiovascular reflex control devices
US6985774B2 (en) 2000-09-27 2006-01-10 Cvrx, Inc. Stimulus regimens for cardiovascular reflex control
US7158832B2 (en) 2000-09-27 2007-01-02 Cvrx, Inc. Electrode designs and methods of use for cardiovascular reflex control devices
US7623926B2 (en) 2000-09-27 2009-11-24 Cvrx, Inc. Stimulus regimens for cardiovascular reflex control
US7616997B2 (en) 2000-09-27 2009-11-10 Kieval Robert S Devices and methods for cardiovascular reflex control via coupled electrodes
US7499742B2 (en) 2001-09-26 2009-03-03 Cvrx, Inc. Electrode structures and methods for their use in cardiovascular reflex control
US7840271B2 (en) 2000-09-27 2010-11-23 Cvrx, Inc. Stimulus regimens for cardiovascular reflex control
US6749600B1 (en) 2000-11-15 2004-06-15 Impulse Dynamics N.V. Braided splittable catheter sheath
US6609025B2 (en) 2001-01-02 2003-08-19 Cyberonics, Inc. Treatment of obesity by bilateral sub-diaphragmatic nerve stimulation
US6564096B2 (en) 2001-02-28 2003-05-13 Robert A. Mest Method and system for treatment of tachycardia and fibrillation
US6684105B2 (en) 2001-08-31 2004-01-27 Biocontrol Medical, Ltd. Treatment of disorders by unidirectional nerve stimulation
US6748271B2 (en) 2001-07-27 2004-06-08 Cardiac Pacemakers, Inc. Method and system for treatment of neurocardiogenic syncope
US8934968B2 (en) 2001-08-03 2015-01-13 Cardiac Pacemakers, Inc. Neurostimulation and coronary artery disease treatment
US6845776B2 (en) 2001-08-27 2005-01-25 Richard S. Stack Satiation devices and methods
US6675809B2 (en) 2001-08-27 2004-01-13 Richard S. Stack Satiation devices and methods
US7097665B2 (en) 2003-01-16 2006-08-29 Synecor, Llc Positioning tools and methods for implanting medical devices
US7974693B2 (en) 2001-08-31 2011-07-05 Bio Control Medical (B.C.M.) Ltd. Techniques for applying, configuring, and coordinating nerve fiber stimulation
US7885709B2 (en) 2001-08-31 2011-02-08 Bio Control Medical (B.C.M.) Ltd. Nerve stimulation for treating disorders
US7778703B2 (en) 2001-08-31 2010-08-17 Bio Control Medical (B.C.M.) Ltd. Selective nerve fiber stimulation for treating heart conditions
US7904176B2 (en) 2006-09-07 2011-03-08 Bio Control Medical (B.C.M.) Ltd. Techniques for reducing pain associated with nerve stimulation
US20140046407A1 (en) 2001-08-31 2014-02-13 Bio Control Medical (B.C.M.) Ltd. Nerve stimulation techniques
US7778711B2 (en) 2001-08-31 2010-08-17 Bio Control Medical (B.C.M.) Ltd. Reduction of heart rate variability by parasympathetic stimulation
US8565896B2 (en) 2010-11-22 2013-10-22 Bio Control Medical (B.C.M.) Ltd. Electrode cuff with recesses
US8571653B2 (en) 2001-08-31 2013-10-29 Bio Control Medical (B.C.M.) Ltd. Nerve stimulation techniques
US20080119898A1 (en) 2005-09-22 2008-05-22 Biocontrol Medical Ltd. Nitric oxide synthase-affecting parasympathetic stimulation
US8615294B2 (en) 2008-08-13 2013-12-24 Bio Control Medical (B.C.M.) Ltd. Electrode devices for nerve stimulation and cardiac sensing
US7308303B2 (en) 2001-11-01 2007-12-11 Advanced Bionics Corporation Thrombolysis and chronic anticoagulation therapy
US6669693B2 (en) 2001-11-13 2003-12-30 Mayo Foundation For Medical Education And Research Tissue ablation device and methods of using
US6741878B2 (en) 2001-12-14 2004-05-25 Biosense Webster, Inc. Basket catheter with improved expansion mechanism
US6746465B2 (en) 2001-12-14 2004-06-08 The Regents Of The University Of California Catheter based balloon for therapy modification and positioning of tissue
US8233991B2 (en) 2002-02-04 2012-07-31 Boston Scientific Neuromodulation Corporation Method for programming implantable device
US7146984B2 (en) 2002-04-08 2006-12-12 Synecor, Llc Method and apparatus for modifying the exit orifice of a satiation pouch
US7162303B2 (en) 2002-04-08 2007-01-09 Ardian, Inc. Renal nerve stimulation method and apparatus for treatment of patients
US7386346B2 (en) 2002-04-22 2008-06-10 Medtronic, Inc. Controlled and modulated high power racing combined with intracardiac pressure monitoring feedback system utilizing the chronicle implantable hemodynamic monitoring (IHM) and calculated EPAD
US7862513B2 (en) 2002-05-14 2011-01-04 Pacesetter, Inc. Apparatus for minimally invasive calibration of implanted pressure transducers
US20050065553A1 (en) 2003-06-13 2005-03-24 Omry Ben Ezra Applications of vagal stimulation
US7321793B2 (en) 2003-06-13 2008-01-22 Biocontrol Medical Ltd. Vagal stimulation for atrial fibrillation therapy
US8204591B2 (en) 2002-05-23 2012-06-19 Bio Control Medical (B.C.M.) Ltd. Techniques for prevention of atrial fibrillation
US20120303080A1 (en) 2003-06-13 2012-11-29 Bio Control Medical (B.C.M.) Ltd. Parasympathetic nerve stimulation
US8036745B2 (en) 2004-06-10 2011-10-11 Bio Control Medical (B.C.M.) Ltd. Parasympathetic pacing therapy during and following a medical procedure, clinical trauma or pathology
US20140214135A1 (en) 2002-05-23 2014-07-31 Bio Control Medical (B.C.M.) Ltd. Dissolvable electrode device
US7277761B2 (en) 2002-06-12 2007-10-02 Pacesetter, Inc. Vagal stimulation for improving cardiac function in heart failure or CHF patients
US7904151B2 (en) 2002-07-24 2011-03-08 Bio Control Medical (B.C.M.) Ltd. Parasympathetic stimulation for treating ventricular arrhythmia
US6944490B1 (en) 2002-09-25 2005-09-13 Advanced Cardiovascular Systems, Inc. Apparatus and method for positioning and delivering a therapeutic tool to the inside of a heart
US7027851B2 (en) * 2002-10-30 2006-04-11 Biosense Webster, Inc. Multi-tip steerable catheter
US7277757B2 (en) 2002-10-31 2007-10-02 Medtronic, Inc. Respiratory nerve stimulation
US7285287B2 (en) 2002-11-14 2007-10-23 Synecor, Llc Carbon dioxide-assisted methods of providing biocompatible intraluminal prostheses
US6887266B2 (en) 2002-11-14 2005-05-03 Synecor, Llc Endoprostheses and methods of manufacture
US20040098090A1 (en) 2002-11-14 2004-05-20 Williams Michael S. Polymeric endoprosthesis and method of manufacture
US7163554B2 (en) 2002-11-15 2007-01-16 Synecor, Llc Endoprostheses and methods of manufacture
WO2004045653A2 (en) 2002-11-15 2004-06-03 Synecor, Llc Polymeric endoprosthesis and method of manufacture
US20050187615A1 (en) 2004-02-23 2005-08-25 Williams Michael S. Polymeric endoprostheses with enhanced strength and flexibility and methods of manufacture
US7704276B2 (en) 2002-11-15 2010-04-27 Synecor, Llc Endoprostheses and methods of manufacture
US7555351B2 (en) 2002-12-19 2009-06-30 Cardiac Pacemakers, Inc. Pulmonary artery lead for atrial therapy and atrial pacing and sensing
US7857748B2 (en) 2003-01-15 2010-12-28 Syne Cor, Llc Photocurable endoprosthesis methods of manufacture
US7387629B2 (en) 2003-01-21 2008-06-17 St. Jude Medical, Atrial Fibrillation Division, Inc. Catheter design that facilitates positioning at tissue to be diagnosed or treated
US6885889B2 (en) 2003-02-28 2005-04-26 Medtronic, Inc. Method and apparatus for optimizing cardiac resynchronization therapy based on left ventricular acceleration
WO2004080533A1 (en) 2003-03-10 2004-09-23 Impulse Dynamics Nv Apparatus and method for delivering electrical signals to modify gene expression in cardiac tissue
US6932930B2 (en) 2003-03-10 2005-08-23 Synecor, Llc Intraluminal prostheses having polymeric material with selectively modified crystallinity and methods of making same
US7276062B2 (en) 2003-03-12 2007-10-02 Biosence Webster, Inc. Deflectable catheter with hinge
US7658709B2 (en) 2003-04-09 2010-02-09 Medtronic, Inc. Shape memory alloy actuators
US6832478B2 (en) 2003-04-09 2004-12-21 Medtronic, Inc. Shape memory alloy actuators
US20080046016A1 (en) 2003-05-23 2008-02-21 Biocontrol Medical Ltd. Intravascular parasympatheticstimulation for atrial cardioversion
US8060197B2 (en) 2003-05-23 2011-11-15 Bio Control Medical (B.C.M.) Ltd. Parasympathetic stimulation for termination of non-sinus atrial tachycardia
US7082336B2 (en) 2003-06-04 2006-07-25 Synecor, Llc Implantable intravascular device for defibrillation and/or pacing
US7617007B2 (en) 2003-06-04 2009-11-10 Synecor Llc Method and apparatus for retaining medical implants within body vessels
US8239045B2 (en) 2003-06-04 2012-08-07 Synecor Llc Device and method for retaining a medical device within a vessel
US7529589B2 (en) 2003-06-04 2009-05-05 Synecor Llc Intravascular electrophysiological system and methods
EP1648560A4 (en) 2003-06-13 2015-10-28 Biocontrol Medical Ltd VAGAL STIMULATION FOR ANTI-EMBOLIC THERAPY
US7092759B2 (en) 2003-07-30 2006-08-15 Medtronic, Inc. Method of optimizing cardiac resynchronization therapy using sensor signals of septal wall motion
US7291146B2 (en) 2003-09-12 2007-11-06 Minnow Medical, Inc. Selectable eccentric remodeling and/or ablation of atherosclerotic material
US20050247320A1 (en) 2003-10-10 2005-11-10 Stack Richard S Devices and methods for retaining a gastro-esophageal implant
US8206456B2 (en) 2003-10-10 2012-06-26 Barosense, Inc. Restrictive and/or obstructive implant system for inducing weight loss
US7480532B2 (en) 2003-10-22 2009-01-20 Cvrx, Inc. Baroreflex activation for pain control, sedation and sleep
US20050119752A1 (en) 2003-11-19 2005-06-02 Synecor Llc Artificial intervertebral disc
US7377939B2 (en) 2003-11-19 2008-05-27 Synecor, Llc Highly convertible endolumenal prostheses and methods of manufacture
EP1701766A2 (en) * 2003-12-12 2006-09-20 Synecor, LLC Implantable medical device having pre-implant exoskeleton
US20080015659A1 (en) 2003-12-24 2008-01-17 Yi Zhang Neurostimulation systems and methods for cardiac conditions
US8126560B2 (en) 2003-12-24 2012-02-28 Cardiac Pacemakers, Inc. Stimulation lead for stimulating the baroreceptors in the pulmonary artery
US7460906B2 (en) 2003-12-24 2008-12-02 Cardiac Pacemakers, Inc. Baroreflex stimulation to treat acute myocardial infarction
US20050149132A1 (en) 2003-12-24 2005-07-07 Imad Libbus Automatic baroreflex modulation based on cardiac activity
US7643875B2 (en) 2003-12-24 2010-01-05 Cardiac Pacemakers, Inc. Baroreflex stimulation system to reduce hypertension
US8126559B2 (en) 2004-11-30 2012-02-28 Cardiac Pacemakers, Inc. Neural stimulation with avoidance of inappropriate stimulation
US8024050B2 (en) 2003-12-24 2011-09-20 Cardiac Pacemakers, Inc. Lead for stimulating the baroreceptors in the pulmonary artery
US20050273146A1 (en) 2003-12-24 2005-12-08 Synecor, Llc Liquid perfluoropolymers and medical applications incorporating same
US7869881B2 (en) 2003-12-24 2011-01-11 Cardiac Pacemakers, Inc. Baroreflex stimulator with integrated pressure sensor
US20050271794A1 (en) 2003-12-24 2005-12-08 Synecor, Llc Liquid perfluoropolymers and medical and cosmetic applications incorporating same
US7486991B2 (en) 2003-12-24 2009-02-03 Cardiac Pacemakers, Inc. Baroreflex modulation to gradually decrease blood pressure
US7873413B2 (en) 2006-07-24 2011-01-18 Cardiac Pacemakers, Inc. Closed loop neural stimulation synchronized to cardiac cycles
US20050142315A1 (en) 2003-12-24 2005-06-30 Desimone Joseph M. Liquid perfluoropolymers and medical applications incorporating same
US7509166B2 (en) 2003-12-24 2009-03-24 Cardiac Pacemakers, Inc. Automatic baroreflex modulation responsive to adverse event
US7706884B2 (en) 2003-12-24 2010-04-27 Cardiac Pacemakers, Inc. Baroreflex stimulation synchronized to circadian rhythm
US7295881B2 (en) 2003-12-29 2007-11-13 Biocontrol Medical Ltd. Nerve-branch-specific action-potential activation, inhibition, and monitoring
WO2005067817A1 (en) 2004-01-13 2005-07-28 Remon Medical Technologies Ltd Devices for fixing a sensor in a body lumen
US7547286B2 (en) 2004-02-16 2009-06-16 Choate John I M Method to reduce inflammation and tactile finger sensation deficit due to carpal tunnel syndrome or arthritis
US20050187556A1 (en) 2004-02-25 2005-08-25 Synecor, Llc Universal percutaneous spinal access system
US8352031B2 (en) 2004-03-10 2013-01-08 Impulse Dynamics Nv Protein activity modification
WO2006007048A2 (en) 2004-05-04 2006-01-19 The Cleveland Clinic Foundation Methods of treating medical conditions by neuromodulation of the sympathetic nervous system
US8412348B2 (en) 2004-05-06 2013-04-02 Boston Scientific Neuromodulation Corporation Intravascular self-anchoring integrated tubular electrode body
US7260431B2 (en) 2004-05-20 2007-08-21 Cardiac Pacemakers, Inc. Combined remodeling control therapy and anti-remodeling therapy by implantable cardiac device
US8116881B2 (en) 2004-06-10 2012-02-14 Bio Control Medical (B.C.M.) Ltd Electrode assembly for nerve control
WO2006012050A2 (en) 2004-06-30 2006-02-02 Cvrx, Inc. Connection structures for extra-vascular electrode lead body
US7532938B2 (en) * 2004-09-10 2009-05-12 The Cleveland Clinic Foundation Intraluminal electrode assembly
WO2006039409A1 (en) 2004-09-30 2006-04-13 Synecor, Llc Artificial intervertebral disc nucleus
US20060074453A1 (en) 2004-10-04 2006-04-06 Cvrx, Inc. Baroreflex activation and cardiac resychronization for heart failure treatment
US8175705B2 (en) 2004-10-12 2012-05-08 Cardiac Pacemakers, Inc. System and method for sustained baroreflex stimulation
US8244355B2 (en) 2004-10-29 2012-08-14 Medtronic, Inc. Method and apparatus to provide diagnostic index and therapy regulated by subject's autonomic nervous system
US7468062B2 (en) 2004-11-24 2008-12-23 Ablation Frontiers, Inc. Atrial ablation catheter adapted for treatment of septal wall arrhythmogenic foci and method of use
US7891085B1 (en) 2005-01-11 2011-02-22 Boston Scientific Neuromodulation Corporation Electrode array assembly and method of making same
US7672724B2 (en) 2005-01-18 2010-03-02 Cardiac Pacemakers, Inc. Method and apparatus for optimizing electrical stimulation parameters using heart rate variability
US8609082B2 (en) 2005-01-25 2013-12-17 Bio Control Medical Ltd. Administering bone marrow progenitor cells or myoblasts followed by application of an electrical current for cardiac repair, increasing blood supply or enhancing angiogenesis
US20060178586A1 (en) 2005-02-07 2006-08-10 Dobak John D Iii Devices and methods for accelerometer-based characterization of cardiac function and identification of LV target pacing zones
US8224444B2 (en) 2005-02-18 2012-07-17 Bio Control Medical (B.C.M.) Ltd. Intermittent electrical stimulation
US7769446B2 (en) 2005-03-11 2010-08-03 Cardiac Pacemakers, Inc. Neural stimulation system for cardiac fat pads
US7363082B2 (en) 2005-03-24 2008-04-22 Synecor Llc Flexible hermetic enclosure for implantable medical devices
US7542800B2 (en) 2005-04-05 2009-06-02 Cardiac Pacemakers, Inc. Method and apparatus for synchronizing neural stimulation to cardiac cycles
US7499748B2 (en) 2005-04-11 2009-03-03 Cardiac Pacemakers, Inc. Transvascular neural stimulation device
US7881782B2 (en) 2005-04-20 2011-02-01 Cardiac Pacemakers, Inc. Neural stimulation system to prevent simultaneous energy discharges
US7904158B2 (en) 2005-04-28 2011-03-08 Medtronic, Inc. Measurement of coronary sinus parameters to optimize left ventricular performance
EP1898991B1 (en) 2005-05-04 2016-06-29 Impulse Dynamics NV Protein activity modification
US7561923B2 (en) 2005-05-09 2009-07-14 Cardiac Pacemakers, Inc. Method and apparatus for controlling autonomic balance using neural stimulation
US7734348B2 (en) 2005-05-10 2010-06-08 Cardiac Pacemakers, Inc. System with left/right pulmonary artery electrodes
US7765000B2 (en) 2005-05-10 2010-07-27 Cardiac Pacemakers, Inc. Neural stimulation system with pulmonary artery lead
US7617003B2 (en) 2005-05-16 2009-11-10 Cardiac Pacemakers, Inc. System for selective activation of a nerve trunk using a transvascular reshaping lead
US7966067B2 (en) 2005-09-06 2011-06-21 Impulse Dynamics Nv Apparatus and method for delivering electrical signals to a heart
US8731659B2 (en) 2005-09-20 2014-05-20 Cardiac Pacemakers, Inc. Multi-site lead/system using a multi-pole connection and methods therefor
US7616990B2 (en) 2005-10-24 2009-11-10 Cardiac Pacemakers, Inc. Implantable and rechargeable neural stimulator
US8226637B2 (en) * 2005-11-01 2012-07-24 Japan Electel, Inc. Balloon catheter system
US7630760B2 (en) 2005-11-21 2009-12-08 Cardiac Pacemakers, Inc. Neural stimulation therapy system for atherosclerotic plaques
JP5256048B2 (ja) 2006-02-03 2013-08-07 シネコー・エルエルシー 神経調節のための脈管内デバイス
WO2007091244A1 (en) 2006-02-07 2007-08-16 Impulse Dynamics Nv Assessing cardiac activity
US8457763B2 (en) 2006-04-27 2013-06-04 Medtronic, Inc. Implantable medical electrical stimulation lead fixation method and apparatus
US8005543B2 (en) 2006-05-08 2011-08-23 Cardiac Pacemakers, Inc. Heart failure management system
US7801604B2 (en) 2006-08-29 2010-09-21 Cardiac Pacemakers, Inc. Controlled titration of neurostimulation therapy
US8620422B2 (en) 2006-09-28 2013-12-31 Cvrx, Inc. Electrode array structures and methods of use for cardiovascular reflex control
US9643004B2 (en) 2006-10-31 2017-05-09 Medtronic, Inc. Implantable medical elongated member with adhesive elements
US7805194B1 (en) 2006-11-03 2010-09-28 Pacesetter, Inc. Matrix optimization method of individually adapting therapy in an implantable cardiac therapy device
US8311633B2 (en) 2006-12-04 2012-11-13 Synecor Llc Intravascular implantable device having superior anchoring arrangement
WO2008070189A2 (en) 2006-12-06 2008-06-12 The Cleveland Clinic Foundation Method and system for treating acute heart failure by neuromodulation
US8337518B2 (en) * 2006-12-20 2012-12-25 Onset Medical Corporation Expandable trans-septal sheath
US8005545B2 (en) 2007-01-24 2011-08-23 Bio Control Medical (B.C.M.) Ltd. Parasympathetic stimulation for prevention and treatment of atrial fibrillation
US8150521B2 (en) 2007-03-15 2012-04-03 Cvrx, Inc. Methods and devices for controlling battery life in an implantable pulse generator
US8406877B2 (en) 2007-03-19 2013-03-26 Cardiac Pacemakers, Inc. Selective nerve stimulation with optionally closed-loop capabilities
US7970871B2 (en) 2007-05-02 2011-06-28 Synapse Wireless, Inc. Systems and methods for dynamically configuring node behavior in a sensor network
US20080275349A1 (en) 2007-05-02 2008-11-06 Earlysense Ltd. Monitoring, predicting and treating clinical episodes
US20090018596A1 (en) 2007-05-15 2009-01-15 Cvrx, Inc. Baroreflex activation therapy device with pacing cardiac electrical signal detection capability
US8901878B2 (en) 2007-06-05 2014-12-02 Impulse Dynamics Nv Transcutaneous charging device
US20090012546A1 (en) 2007-07-03 2009-01-08 Synecor, Llc Devices for treating gastroesophageal reflux disease and hiatal hernia, and methods of treating gastroesophageal reflux disease and hiatal hernia using same
US20090012542A1 (en) 2007-07-03 2009-01-08 Synecor, Llc Satiation devices and methods for controlling obesity
US8249717B2 (en) 2007-07-18 2012-08-21 Cardiac Pacemakers, Inc. Systems and methods for providing neural stimulation transitions
US7848812B2 (en) 2007-07-20 2010-12-07 Cvrx, Inc. Elective service indicator based on pulse count for implantable device
US7676266B1 (en) 2007-07-30 2010-03-09 Pacesetter, Inc. Monitoring ventricular synchrony
US8060218B2 (en) 2007-08-02 2011-11-15 Synecor, Llc Inductive element for intravascular implantable devices
US8027724B2 (en) 2007-08-03 2011-09-27 Cardiac Pacemakers, Inc. Hypertension diagnosis and therapy using pressure sensor
US8265736B2 (en) 2007-08-07 2012-09-11 Cardiac Pacemakers, Inc. Method and apparatus to perform electrode combination selection
US8454596B2 (en) * 2007-08-10 2013-06-04 Beijing Amsino Medical Co., Ltd. Electrophysiology ablation device
US8204596B2 (en) 2007-10-31 2012-06-19 Synecor Llc Isolation connector for an intravascular implantable medical device
CN101939048B (zh) 2007-12-12 2015-06-17 心脏起搏器股份公司 用于从肺动脉递送神经刺激的系统
US8155744B2 (en) 2007-12-13 2012-04-10 The Cleveland Clinic Foundation Neuromodulatory methods for treating pulmonary disorders
US8216225B2 (en) 2007-12-21 2012-07-10 St. Jude Medical, Atrial Fibrillation Division, Inc. Irrigated ablation electrode assembly having a polygonal electrode
US8538535B2 (en) 2010-08-05 2013-09-17 Rainbow Medical Ltd. Enhancing perfusion by contraction
US8626299B2 (en) 2008-01-31 2014-01-07 Enopace Biomedical Ltd. Thoracic aorta and vagus nerve stimulation
US9005106B2 (en) 2008-01-31 2015-04-14 Enopace Biomedical Ltd Intra-aortic electrical counterpulsation
US20140114377A1 (en) 2008-01-31 2014-04-24 Enopace Biomedical Ltd. Vagus nerve stimulation
US8626290B2 (en) 2008-01-31 2014-01-07 Enopace Biomedical Ltd. Acute myocardial infarction treatment by electrical stimulation of the thoracic aorta
US20150151121A1 (en) 2008-01-31 2015-06-04 Enopace Biomedical Ltd. Enhancing perfusion by contraction
WO2009111528A2 (en) 2008-03-05 2009-09-11 Robert Hoch Pressure sensing catheter
US7925352B2 (en) 2008-03-27 2011-04-12 Synecor Llc System and method for transvascularly stimulating contents of the carotid sheath
US8315713B2 (en) 2008-04-30 2012-11-20 Medtronic, Inc. Techniques for placing medical leads for electrical stimulation of nerve tissue
US8103360B2 (en) 2008-05-09 2012-01-24 Foster Arthur J Medical lead coil conductor with spacer element
US8239037B2 (en) 2008-07-06 2012-08-07 Synecor Llc Intravascular implant anchors having remote communication and/or battery recharging capabilities
US8160701B2 (en) 2008-07-08 2012-04-17 Cardiac Pacemakers, Inc. Systems and methods for delivering vagal nerve stimulation
US9717914B2 (en) 2008-09-16 2017-08-01 Pacesetter, Inc. Use of cardiohemic vibration for pacing therapies
CN102176861B (zh) 2008-10-10 2015-11-25 心脏起搏器公司 用于心力衰竭患者管理的多传感器策略
US8386053B2 (en) 2008-10-31 2013-02-26 Medtronic, Inc. Subclavian ansae stimulation
US8712550B2 (en) * 2008-12-30 2014-04-29 Biosense Webster, Inc. Catheter with multiple electrode assemblies for use at or near tubular regions of the heart
US8706230B2 (en) 2009-04-23 2014-04-22 Impulse Dynamics Nv Implantable lead connector
US8521245B2 (en) 2009-09-11 2013-08-27 Medtronic, Inc. Method and apparatus for post-shock evaluation using tissue oxygenation measurements
US20110082452A1 (en) 2009-10-02 2011-04-07 Cardiofocus, Inc. Cardiac ablation system with automatic safety shut-off feature
US8412326B2 (en) 2009-10-30 2013-04-02 Cardiac Pacemakers, Inc. Pacemaker with vagal surge monitoring and response
US8979839B2 (en) 2009-11-13 2015-03-17 St. Jude Medical, Inc. Assembly of staggered ablation elements
WO2011075328A1 (en) * 2009-12-14 2011-06-23 Mayo Foundation For Medical Education And Research Device and method for treating cardiac disorders by modulating autonomic response
US8249706B2 (en) 2010-01-26 2012-08-21 Pacesetter, Inc. Adaptive rate programming control in implantable medical devices using ventricular-arterial coupling surrogates
US9050453B2 (en) 2010-03-19 2015-06-09 National Cerebral And Cardiovascular Center Electrostimulation system, and electrostimulation electrode assembly and biological implantable electrode therefore
JP5624672B2 (ja) 2010-04-15 2014-11-12 カーディアック ペースメイカーズ, インコーポレイテッド 断続的神経刺激による過渡反応を使用する自律神経調節
US9408661B2 (en) 2010-07-30 2016-08-09 Patrick A. Haverkost RF electrodes on multiple flexible wires for renal nerve ablation
EP2608840B1 (de) * 2010-08-26 2017-10-25 Acandis GmbH & Co. KG Elektrode für medizinische anwendungen, system mit einer elektrode und verfahren zur herstellung einer elektrode
US20130018444A1 (en) 2011-07-11 2013-01-17 Glenn Richard A Intravascular electrodes for transvascular stimulation
US20150150508A1 (en) 2010-08-31 2015-06-04 Interventional Autonomics Corporation Intravascular electrodes and anchoring devices for transvascular stimulation
US8934956B2 (en) 2010-08-31 2015-01-13 Interventional Autonomics Corporation Intravascular electrodes and anchoring devices for transvascular stimulation
EP3002037B1 (en) 2010-09-15 2018-06-06 Cardiac Pacemakers, Inc. Automatic selection of lead configuration for a neural stimulation lead
ES2751156T3 (es) * 2010-10-20 2020-03-30 Medtronic Ardian Luxembourg Aparatos de catéter que tienen estructuras de malla expansibles para neuromodulación renal
US8437867B2 (en) 2010-10-29 2013-05-07 Cvrx, Inc. Implant tool and improved electrode design for minimally invasive procedure
US9017323B2 (en) 2010-11-16 2015-04-28 Tva Medical, Inc. Devices and methods for forming a fistula
US8781582B2 (en) 2011-01-19 2014-07-15 Medtronic, Inc. Vagal stimulation
US20120197141A1 (en) 2011-01-28 2012-08-02 Pacesetter, Inc. Implantable echo doppler flow sensor for monitoring of hemodynamics
JP5331836B2 (ja) * 2011-02-21 2013-10-30 コヴィディエン リミテッド パートナーシップ 管路内に閉塞装置を供給して展開するためのシステム及び方法
US8983601B2 (en) 2011-02-25 2015-03-17 The Cleveland Clinic Foundation Extravascular neuromodulation to treat heart failure
US20120232563A1 (en) 2011-03-08 2012-09-13 Medtronic, Inc. Implant catheters for physiological pacing
US8734388B2 (en) * 2011-04-01 2014-05-27 Rutgers, The State University Of New Jersey Catheter for minimally invasive cardiac pacing surgery and method of use
US9511229B2 (en) 2011-06-28 2016-12-06 Boston Scientific Neuromodulation Corporation System and method for using impedance to determine proximity and orientation of segmented electrodes
US20130072995A1 (en) 2011-07-11 2013-03-21 Terrance Ransbury Catheter system for acute neuromodulation
US9446240B2 (en) 2011-07-11 2016-09-20 Interventional Autonomics Corporation System and method for neuromodulation
WO2013022543A2 (en) 2011-07-11 2013-02-14 Synecor Llc Catheter system for acute neuromodulation
US8855783B2 (en) 2011-09-09 2014-10-07 Enopace Biomedical Ltd. Detector-based arterial stimulation
EP2757984B1 (en) 2011-09-19 2018-08-29 Boston Scientific Scimed, Inc. Subintimal re-entry catheter and retrograde recanalization
US10463259B2 (en) 2011-10-28 2019-11-05 Three Rivers Cardiovascular Systems Inc. System and apparatus comprising a multi-sensor catheter for right heart and pulmonary artery catheterization
US9119600B2 (en) 2011-11-15 2015-09-01 Boston Scientific Scimed, Inc. Device and methods for renal nerve modulation monitoring
US9005100B2 (en) 2011-12-15 2015-04-14 The Board Of Trustees Of The Leland Stanford Jr. University Apparatus and methods for treating pulmonary hypertension
US8825130B2 (en) 2011-12-30 2014-09-02 St. Jude Medical, Atrial Fibrillation Division, Inc. Electrode support structure assemblies
US20140074148A1 (en) 2012-02-21 2014-03-13 Synecor Llc Embolic protection system and method for use in an aortic arch
US9314299B2 (en) * 2012-03-21 2016-04-19 Biosense Webster (Israel) Ltd. Flower catheter for mapping and ablating veinous and other tubular locations
WO2013165920A1 (en) 2012-04-29 2013-11-07 Synecor Llc Intravascular electrode arrays for neuromodulation
EP2858711B1 (en) 2012-06-06 2018-03-07 Magenta Medical Ltd. Prosthetic renal valve
US9168094B2 (en) * 2012-07-05 2015-10-27 Mc10, Inc. Catheter device including flow sensing
EP2887890A4 (en) 2012-08-23 2016-05-18 Minimally Invasive Surgical Access Ltd SYSTEM FOR DIRECT AORTA ACCESS FOR AORTIC FLAP TRANSACTION METHODS
WO2014032038A1 (en) 2012-08-24 2014-02-27 Synecor Llc System for facilitating transcatheter aortic valve procedures using femoral access
US9833608B2 (en) 2012-11-20 2017-12-05 NeuroTronik IP Holding (Jersey) Limited Positioning methods for intravascular electrode arrays for neuromodulation
US11202904B2 (en) 2012-11-20 2021-12-21 Nuxcel Limited Positioning methods for intravascular electrode arrays for neuromodulation
US9446243B2 (en) 2012-12-07 2016-09-20 Boston Scientific Neuromodulation Corporation Patient posture determination and stimulation program adjustment in an implantable stimulator device using impedance fingerprinting
WO2014093178A2 (en) 2012-12-14 2014-06-19 Boston Scientific Neuromodulation Corporation Method for automation of therapy-based programming in a tissue stimulator user interface
JP6437997B2 (ja) 2013-03-12 2018-12-12 カーディアック ペースメイカーズ, インコーポレイテッド 複数のセンサの融合を備えた医療デバイス
EP3653113B1 (en) 2013-03-13 2022-05-04 Magenta Medical Ltd. Impeller with hollow central lumen
US9494960B2 (en) 2013-03-14 2016-11-15 Boston Scientific Neuromodulation Corporation Voltage regulator programmable as a function of load current
US9242097B2 (en) 2013-06-18 2016-01-26 Cardiac Pacemakers, Inc. System and method for mapping baroreceptors
WO2015057521A1 (en) 2013-10-14 2015-04-23 Boston Scientific Scimed, Inc. High resolution cardiac mapping electrode array catheter
CN105813687B (zh) 2013-12-05 2018-03-27 心脏起搏器股份公司 自主调制治疗的定剂量的递送
US9764113B2 (en) 2013-12-11 2017-09-19 Magenta Medical Ltd Curved catheter
CN103750899B (zh) * 2014-01-21 2016-04-27 深圳市惠泰医疗器械有限公司 多电极网篮导管及其制备方法
AU2015229669A1 (en) 2014-03-09 2016-09-29 Neuro Tronik Ip Holding (Jersey) Limited Systems and methods for neuromodulation of sympathetic and parasympathetic cardiac nerves
US9415224B2 (en) 2014-04-25 2016-08-16 Cyberonics, Inc. Neurostimulation and recording of physiological response for the treatment of chronic cardiac dysfunction
US9597515B2 (en) 2014-03-28 2017-03-21 Cardiac Pacemakers, Inc. Systems and methods for facilitating selection of one or more vectors in a medical device
CN106456975B (zh) 2014-05-22 2020-09-04 卡迪诺米克公司 用于电神经调制的导管和导管系统
JP2017522923A (ja) 2014-06-03 2017-08-17 ボストン サイエンティフィック サイムド,インコーポレイテッドBoston Scientific Scimed,Inc. 非外傷性の遠位チップを備えた電極アセンブリ
JP2017516588A (ja) 2014-06-04 2017-06-22 ボストン サイエンティフィック サイムド,インコーポレイテッドBoston Scientific Scimed,Inc. 電極組立体
US20170312525A1 (en) 2014-08-06 2017-11-02 NeuroTronik IP Holding (Jersey) Limited Systems and methods for neuromodulation of sympathetic and parasympathetic cardiac nerves
EP3194017A1 (en) 2014-09-08 2017-07-26 Cardionomic, Inc. Methods for electrical neuromodulation of the heart
AU2015315658B2 (en) 2014-09-08 2019-05-23 CARDIONOMIC, Inc. Catheter and electrode systems for electrical neuromodulation
US20160174864A1 (en) 2014-12-18 2016-06-23 Biosense Webster (Israel) Ltd. Far Field-Insensitive Intracardiac Catheter Electrodes
EP3610917A1 (en) 2015-01-05 2020-02-19 Cardionomic, Inc. Cardiac modulation facilitation methods and systems
US20180236220A1 (en) 2015-01-14 2018-08-23 NeuroTronik IP Holding (Jersey) Limited Inflatable intravascular electrode supports for neuromodulation
CN107405491B (zh) 2015-01-30 2021-06-01 心脏起搏器股份公司 生理事件检测和数据存储
US9855317B2 (en) 2015-04-27 2018-01-02 Reflex Medical, Inc. Systems and methods for sympathetic cardiopulmonary neuromodulation
WO2016195477A1 (en) 2015-06-04 2016-12-08 Jozef Reinier Cornelis Jansen Method and computer system for processing a heart sensor output
US20170065818A1 (en) 2015-09-08 2017-03-09 Interventional Autonomics Corporation Neuromodulation Systems and Methods for Treating Acute Heart Failure Syndromes
SG11201807446UA (en) 2016-03-09 2018-09-27 Cardionomic Inc Cardiac contractility neurostimulation systems and methods
US11026619B2 (en) 2016-04-13 2021-06-08 Cardiac Pacemakers, Inc. Determining cardiac pacing capture effectiveness of an implantable medical device
US10639478B2 (en) 2017-01-31 2020-05-05 NeuroTronik IP Holding (Jersey) Limited Enhancing left ventricular relaxation through neuromodulation
CN110505841B (zh) 2017-04-05 2022-09-23 美敦力瓦斯科尔勒公司 定尺寸导管、确定复杂解剖结构的尺寸的方法以及选择用于植入的假体的方法

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070135875A1 (en) * 2002-04-08 2007-06-14 Ardian, Inc. Methods and apparatus for thermally-induced renal neuromodulation
WO2012149511A2 (en) * 2011-04-28 2012-11-01 Synecor Llc Neuromodulation systems and methods for treating acute heart failure syndromes
CN103239799A (zh) * 2013-05-21 2013-08-14 重庆绿色智能技术研究院 用于膀胱功能性电刺激的电极

Also Published As

Publication number Publication date
AU2015264121B2 (en) 2020-05-28
US10576273B2 (en) 2020-03-03
JP6856721B2 (ja) 2021-04-07
EP3145583B1 (en) 2022-03-02
US20200197692A1 (en) 2020-06-25
CN106456975A (zh) 2017-02-22
JP2019213925A (ja) 2019-12-19
JP6580068B2 (ja) 2019-09-25
JP2017516523A (ja) 2017-06-22
WO2015179634A3 (en) 2016-05-19
CN111790047A (zh) 2020-10-20
US20170065812A1 (en) 2017-03-09
EP3145583A2 (en) 2017-03-29
SG11201608878SA (en) 2016-11-29
CN111790047B (zh) 2022-09-27
CA2946791C (en) 2023-09-19
SG10201808553QA (en) 2018-11-29
CA2946791A1 (en) 2015-11-26
WO2015179634A2 (en) 2015-11-26
AU2015264121A1 (en) 2016-11-10

Similar Documents

Publication Publication Date Title
CN106456975B (zh) 用于电神经调制的导管和导管系统
US11806159B2 (en) Differential on and off durations for neurostimulation devices and methods
US20210370068A1 (en) Floatable catheters for neuromodulation
US20240325758A1 (en) Methods of selecting parameters for therapeutic neuromodulation
US20090318749A1 (en) Method and apparatus for pacing and intermittent ischemia
US6006138A (en) Non-invasive cardiac pacing
US20150165207A1 (en) Method and device for respiratory and cardiorespiratory support
US20170173339A1 (en) Methods for electrical neuromodulation of the heart

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant