CN106456658A - 硒有机化合物的组合物和其使用方法 - Google Patents

硒有机化合物的组合物和其使用方法 Download PDF

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Publication number
CN106456658A
CN106456658A CN201480077179.9A CN201480077179A CN106456658A CN 106456658 A CN106456658 A CN 106456658A CN 201480077179 A CN201480077179 A CN 201480077179A CN 106456658 A CN106456658 A CN 106456658A
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compound
alkyl
cells
compounds
formula
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CN201480077179.9A
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Chinese (zh)
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R.鲍威尔
兰子鉴
A.伊安尼库里斯
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Alltech Corp
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Alltech Corp
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Priority to CN202110819326.7A priority Critical patent/CN113694074A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7135—Compounds containing heavy metals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/05—Dipeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Inorganic Chemistry (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Saccharide Compounds (AREA)
CN201480077179.9A 2014-03-14 2014-03-14 硒有机化合物的组合物和其使用方法 Pending CN106456658A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202110819326.7A CN113694074A (zh) 2014-03-14 2014-03-14 硒有机化合物的组合物和其使用方法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2014/029542 WO2015137983A1 (en) 2014-03-14 2014-03-14 Compositions of selenoorganic compounds and methods of use thereof

Related Child Applications (1)

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CN202110819326.7A Division CN113694074A (zh) 2014-03-14 2014-03-14 硒有机化合物的组合物和其使用方法

Publications (1)

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CN106456658A true CN106456658A (zh) 2017-02-22

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CN201480077179.9A Pending CN106456658A (zh) 2014-03-14 2014-03-14 硒有机化合物的组合物和其使用方法
CN202110819326.7A Pending CN113694074A (zh) 2014-03-14 2014-03-14 硒有机化合物的组合物和其使用方法
CN201610827544.4A Active CN106822168B (zh) 2014-03-14 2016-09-14 含硒有机化合物的组合物和其使用方法

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CN201610827544.4A Active CN106822168B (zh) 2014-03-14 2016-09-14 含硒有机化合物的组合物和其使用方法

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US (3) US10201559B2 (cg-RX-API-DMAC7.html)
EP (1) EP3116511B1 (cg-RX-API-DMAC7.html)
JP (2) JP6313479B2 (cg-RX-API-DMAC7.html)
KR (3) KR102466389B1 (cg-RX-API-DMAC7.html)
CN (3) CN106456658A (cg-RX-API-DMAC7.html)
AU (4) AU2014386236B2 (cg-RX-API-DMAC7.html)
BR (1) BR112016020233B1 (cg-RX-API-DMAC7.html)
CA (1) CA2940283C (cg-RX-API-DMAC7.html)
DK (2) DK3116511T3 (cg-RX-API-DMAC7.html)
HU (2) HUE051713T2 (cg-RX-API-DMAC7.html)
IL (1) IL247312A0 (cg-RX-API-DMAC7.html)
MX (2) MX2016011897A (cg-RX-API-DMAC7.html)
PE (1) PE20211069A1 (cg-RX-API-DMAC7.html)
PT (1) PT3116511T (cg-RX-API-DMAC7.html)
RU (2) RU2665135C2 (cg-RX-API-DMAC7.html)
WO (2) WO2015137983A1 (cg-RX-API-DMAC7.html)

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CN110545822A (zh) * 2017-05-19 2019-12-06 全技术公司 药剂、组合物及其相关方法
CN116421618A (zh) * 2023-06-15 2023-07-14 暨南大学 Se@NADH的制备方法及其在脊髓损伤治疗中的应用

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WO2019093699A1 (ko) * 2017-11-09 2019-05-16 서울대학교 산학협력단 셀레노사마필린 a와 그 유도체, 이의 제조방법 및 이를 유효성분으로 포함하는 암 예방 및 치료용 조성물
KR102083180B1 (ko) 2017-11-09 2020-03-02 서울대학교산학협력단 셀레노사마필린 a와 그 유도체, 이의 제조방법, 및 이를 유효성분으로 포함하는 암 예방 및 치료용 조성물
CN108484690B (zh) * 2018-05-16 2021-04-30 新乡拓新药业股份有限公司 一种1,2,3-三-O-乙酰基-5-脱氧-β-D-核糖的制备方法
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EP3908374A4 (en) * 2019-01-09 2022-12-28 Epitracker, Inc. COMPOSITIONS AND METHODS FOR DIAGNOSIS AND TREATMENT OF NEURODEGENERATIVE DISEASES
JP7404382B2 (ja) 2019-03-04 2023-12-25 エピトラッカー インコーポレイテッド 脂肪酸アナログ、ならびに認知機能障害、行動症状および慢性疼痛の処置におけるそれらの使用
CN111543641A (zh) * 2020-04-27 2020-08-18 江苏惠利生物科技有限公司 一种提高l-硒-甲基硒代半胱氨酸稳定性以及生物利用率的方法
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JP2024539823A (ja) 2021-11-03 2024-10-31 エピトラッカー インコーポレイテッド 老化の質および寿命に関係する状態の治療のためのペンタデカノイルカルニチン
JP2023076373A (ja) * 2021-11-22 2023-06-01 マルサンアイ株式会社 アミロイドβ凝集抑制剤とこれを含む医薬組成物および飲食品、ネプリライシン産生促進剤およびγ－セクレターゼ産生抑制剤
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Cited By (3)

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Publication number Priority date Publication date Assignee Title
CN110545822A (zh) * 2017-05-19 2019-12-06 全技术公司 药剂、组合物及其相关方法
CN116421618A (zh) * 2023-06-15 2023-07-14 暨南大学 Se@NADH的制备方法及其在脊髓损伤治疗中的应用
CN116421618B (zh) * 2023-06-15 2023-09-29 暨南大学 Se@NADH的制备方法及其在脊髓损伤治疗中的应用

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KR20160125989A (ko) 2016-11-01
BR112016020233A2 (cg-RX-API-DMAC7.html) 2017-08-15
CN106822168B (zh) 2020-11-27
US10201559B2 (en) 2019-02-12
WO2015137983A1 (en) 2015-09-17
HUE051713T2 (hu) 2021-03-29
JP6313479B2 (ja) 2018-04-18
DK3116511T3 (da) 2020-11-23
PT3116511T (pt) 2020-11-19
PE20211069A1 (es) 2021-06-09
CA2940283C (en) 2021-03-30
AU2014386236A1 (en) 2016-09-01
KR102448455B1 (ko) 2022-09-28
RU2665135C2 (ru) 2018-08-28
RU2016133469A (ru) 2018-04-17
BR102016021058A2 (pt) 2017-05-30
HUE056172T2 (hu) 2022-01-28
US10201558B2 (en) 2019-02-12
AU2019246818B2 (en) 2021-02-25
WO2017048253A1 (en) 2017-03-23
KR20210104070A (ko) 2021-08-24
EP3116511A1 (en) 2017-01-18
US20160045533A1 (en) 2016-02-18
JP2017078056A (ja) 2017-04-27
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BR112016020233B1 (pt) 2022-07-19
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