CN106265372A - A kind of skin matrix with senile-resistant efficacy and preparation method and application - Google Patents

A kind of skin matrix with senile-resistant efficacy and preparation method and application Download PDF

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CN106265372A
CN106265372A CN201610881195.4A CN201610881195A CN106265372A CN 106265372 A CN106265372 A CN 106265372A CN 201610881195 A CN201610881195 A CN 201610881195A CN 106265372 A CN106265372 A CN 106265372A
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skin matrix
senile
skin
preparation
resistant efficacy
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CN106265372B (en
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刘晶
裴运林
聂艳峰
刘露
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Guangdong Marubi Biological Technology Co Ltd
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Guangdong Marubi Biological Technology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/88Polyamides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations

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  • Botany (AREA)
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  • Mycology (AREA)
  • Cosmetics (AREA)

Abstract

The invention belongs to the technical field of cosmetics, disclose a kind of skin matrix with senile-resistant efficacy and preparation method and application.Described skin matrix, it is made up of following component by mass percentage: Semen Vitis viniferae extract 10%~15%, cocoa extract 15%~20%, elastin hydrolysis 20%~25%, Pollen pini thunbergii dew extract 15%~20%, polyglutamic acid 2%~3%, tetrahydrochysene piperine 0.01%~0.05%, propylene glycol 3%~5%, water surplus.Described skin matrix has good, long-acting wrinkle removing, increases the anti-aging effects of skin elasticity.Described skin matrix is used for preparing cosmetics.

Description

A kind of skin matrix with senile-resistant efficacy and preparation method and application
Technical field
The invention belongs to the technical field of cosmetics, be specifically related to a kind of substrate with senile-resistant efficacy and preparation side thereof Method and application.
Background technology
Along with the growth at age and environmental pollution and the increase of life stress, the skin aging situation of people is increasingly Seriously, the aging of skin has psychology and the physiological effect of complexity to the work of people, life, can cause anxiety, depression, from The a series of psychological problems such as inferior, how one of slow down aging focus becoming cosmetic industry research, the skin care item of defying age Increasingly it is subject to people's attention.
" slow down aging keeps the skin beauty without age " always is the target of the unremitting pursuit of people, because nature is not Evitable rule and existence rule, an old and feeble word is exactly devil, and no matter whether it arrives, and spirals on our crown the most all the time, Tangle our heart.
The obvious characteristic of skin aging is the appearance of wrinkle and lax generation, skin become coarse, wrinkle deepen overstriking, Epidermal structure is abnormal, " yellow-faced woman-my wife " " senile plaque " occurs in pigmentation, and elasticity of skin no longer, becomes lax, vasodilation, epidermis Dyskeratosis etc..
At present the most general anti-aging skin care product is many carries out declaring of defying age with antioxidation, but the machine of defying age Manage more complicated, although the defying age developed according to some mechanism can play certain effect, but general effect is not good enough, because of It is particularly important that this obtains, with research and development, the anti-aging product that effect more highlights by multi-level, multi-angle, multipath slow down aging.
Summary of the invention
In order to overcome the shortcoming and defect of prior art, the primary and foremost purpose of the present invention is that providing one to have significantly improves The senile-resistant efficacy skin matrix such as skin elasticity, desalination wrinkle.
Another object of the present invention is to provide the preparation method of above-mentioned skin matrix.
It is still another object of the present invention to provide the application of above-mentioned skin matrix.
The purpose of the present invention is achieved through the following technical solutions:
A kind of skin matrix with senile-resistant efficacy, is made up of following component by mass percentage:
In described skin matrix, Fructus Vitis viniferae (VITIS VINIFERA) seed extract, cocoa (THEOBROMA CACAO) extract Thing, elastin hydrolysis, Pollen pini thunbergii dew extract, propylene glycol, tetrahydrochysene piperine, polyglutamic acid and water each constituent mass percent Sum is 100%;Described water is ionized water.
The described skin matrix with senile-resistant efficacy is that polyglutamic acid is made into polyglutamic aqueous acid, by tetrahydrochysene recklessly Green pepper alkali is made into the propylene glycol solution of tetrahydrochysene piperine, then by Semen Vitis viniferae extract, cocoa extract, elastin hydrolysis, black The aqueous solution of Truffe extract, the propylene glycol solution of tetrahydrochysene piperine and polyglutamic acid uniformly obtains.
The preparation method of the described skin matrix with senile-resistant efficacy, specifically includes following steps:
(1) open stirring, under the conditions of 40~50 DEG C, polyglutamic acid is slowly added in water, is heated to 85~90 DEG C, protect Temperature, then cools down, and obtains polyglutamic aqueous acid;
(2) tetrahydrochysene piperine is added in propylene glycol, heated and stirred, to be dissolved completely to transparent, obtain tetrahydrochysene piperine Propylene glycol solution;
(3) by Fructus Vitis viniferae (VITIS VINIFERA) seed extract, cocoa (THEOBROMA CACAO) extract, hydrolysis bullet Property albumen, Pollen pini thunbergii dew extract and step (2) tetrahydrochysene piperine propylene glycol solution in, add step (1) polyglutamic acid Aqueous solution in, stirring, low speed homogenizing, filter, discharging, obtain the skin matrix with senile-resistant efficacy.
Described in step (1), temperature retention time is 20~30min, and the temperature of cooling is 35 DEG C~40 DEG C.
Described in step (2), the temperature of heating is 60 DEG C~70 DEG C.
Described in step (3), the speed of stirring is 400~500rpm;Described low speed homogenizing is 1000~1500rpm.
Described in step (3), the time of stirring is 10~15min, and the time of low speed homogenizing is 2~3min.
Described skin matrix is transparency liquid.
Described skin matrix outward appearance is yellow transparent liquid.
A kind of toiletry bag has the skin matrix of senile-resistant efficacy described in containing.
In described cosmetics, the weight content of skin matrix is 15%~35%.
Described cosmetics are skin-care cosmetics, including astringent, essence, emulsion and cream.
A kind of cosmetics comprising skin matrix, are mainly made up of following component by mass percentage:
Component A: deionized water surplus, glycerol 2.0%~8%, propylene glycol 5.0%~10.0%, 1,2-pentanediol 4.0% ~6.0%, carbomer 0.05%~0.25%;
B component: the above-mentioned skin matrix 15%~35% with senile-resistant efficacy;
Component C: triethanolamine 0.05%~0.25%.
Fructus Vitis viniferae (VITIS VINIFERA) seed extract: purchased from BIOSPECTRUM company of Korea S, pH value (25 DEG C): 3.50 ~6.50, proportion (25 DEG C): 0.90~1.10.Semen Vitis viniferae contains procyanidin and the polyphenol of high concentration in extracting, be a kind of strong Effect antioxidant, to free radical resisting and oxidation reaction, thus increases skin elasticity, reduces wrinkle, makes skin maintain younger state, The most also there is the effect dissolving inflammation.
Cocoa (THEOBROMA CACAO) extract: purchased from France Naolys company, pH value (25 DEG C): 4.5~7.5, close Degree: 1.0~1.3g/ml.Cocoa (THEOBROMA CACAO) extract, the cocoa factor of a kind of New Regenerated, making great efforts will be true Cortex densification, helps improve the function repairing skin corium, increases the elasticity of skin;Promote natural reepithelialization;Repair The fiber synthesis of higher and the saccharide albumen of extracellular matrix, thus play the skin that compacts, cell regeneration, restructuring regeneration, increase The function of strong skin barrier.
Elastin hydrolysis: purchased from I.R.A company of Italy, pH value: 6.0~8.0, this elastin hydrolysis comes from greatly The tuna fish skin in the West, less molecular weight can promote that skin sufficiently absorbs, and increases skin collagen protein and elastin laminin contains Amount, significantly improves skin inner tensions and elastic force, makes the collagen protein activity of skin strengthen, and keeps cutin moisture, from inside to outside Improvement and reduce wrinkle, improve and compact sense, increase skin elasticity thus effect of slow down aging.
Pollen pini thunbergii dew extract: purchased from ID bio company, pH value (25 DEG C): 5.5~7.5, density (25 DEG C): 1.10~ 1.20.In Truffe containing the protein of wide variety, 18 kinds of aminoacid (including 8 kinds of essential amino acids that human body can not synthesize), The essential trace elements such as unsaturated fatty acid, multivitamin, zinc, manganese, ferrum, calcium, phosphorus, selenium, and sphingolipid, cerebroside, god Through substantial amounts of metabolites such as amide, triterpene, androsterone, adenosine, Truffe acid, sterol, Truffe polysaccharide, Truffe polypeptide;The most Sugar, polypeptide, triterpene have enhancing immunity, defying age, fatigue-resisting function.Truffe is described as " diamond in food " of preciousness, it Concentration can be helped to improve skin low and deep simple and unadorned, desalinate microgroove, fine and smooth well-balanced shining bright skin, reduction skin gloss.Changing after tested Philanthropist's body skin elasticity, makes human body skin wrinkle restore to the original state, and is respectively provided with preferable effect in terms of even skin tone simultaneously.
Polyglutamic acid: purchased from a Japanese ball company, is to extract from natto, and the inherent moisturizing of innovation can improve skin saturating The content of bright matter acid, improves skin elasticity, reduces dermatitis photoaging.
Tetrahydrochysene piperine: purchased from Sa Binsha company of the U.S., plant origin, is a kind of safe efficient, natural penetrating agent, Onset time is short, promotees to ooze efficiency high and safe and non-stimulating.(because it is oil-soluble product, substrate is water miscible, so adding Before with propylene glycol, it need to be dissolved.)
Propylene glycol: purchased from SKC company of Korea S, relative density (25/25 DEG C): 1.035-1.045.Wetting agent and excellent molten Agent (in this substrate, dissolve tetrahydrochysene piperine).
The present invention through experiment sieving five kinds of wrinkle removing, increase skin elasticity, moisturizing ingredient as functional component, a kind of promote Penetration enhancer, by the interaction between each composition i.e. synergistic function, plays effect of defying age to greatest extent.Due to this Bright active component can be degraded Transdermal absorption by skin, can be that skin supplies nutrition, have long-acting wrinkle removing defying age Effect.
Compared with prior art, the present invention has the following advantages and beneficial effect:
1, the substrate of the present invention has good, long-acting wrinkle removing, increases the anti-aging effects of skin elasticity.
2, the substrate processing technology of the present invention is simple, easy to use.
3, during skin matrix prepared by the present invention makes an addition to the cosmetics such as astringent, emulsion, cream, these product tapes can be given Come moisturizing, wrinkle removing, the effect of increase skin elasticity.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is described in further detail, but embodiments of the present invention are not limited to this.
Embodiment 1
1, the preparation method of a kind of skin matrix with senile-resistant efficacy, concretely comprises the following steps:
(1) open stirring, under the conditions of 50 DEG C, 2 weight portion polyglutamic acids be slowly added in the water of 34.98 weight portions, It is heated to 85 DEG C, is incubated 30min, is cooled to 40 DEG C, obtains polyglutamic acid solution;
(2) 0.02 weight portion tetrahydrochysene piperine is added in 3 parts by weight of propylene glycol, be heated with stirring to 60 DEG C, to be dissolved complete Complete to transparent, obtain the propylene glycol solution of tetrahydrochysene piperine;
(3) by 10 weight portion Fructus Vitis viniferaes (VITIS VINIFERA) seed extract, 15 weight portion cocoa (THEOBROMA CACAO) extract, 20 weight portion elastin hydrolysis, 15 weight portion Pollen pini thunbergiis dew extracts and the tetrahydrochysene piperines of step (2) Propylene glycol solution adds in the polyglutamic acid solution of step (1), stirs 15min, and stirring speed is 400rpm, low speed homogenizing 2min, all Matter speed is 1500rpm, 200 mesh filter-cloth filterings, discharging, i.e. obtains the skin matrix with senile-resistant efficacy.
2, a kind of astringent comprising skin matrix, is made up of following component by mass percentage:
Component A: deionized water 68.8%, glycerol 4.0%, propylene glycol 7.0%, 1,2-pentanediol 5.0%, carbomer 0.1%;
B component: above-mentioned skin matrix 15%;
Component C: triethanolamine 0.1%.
A kind of preparation method of the astringent comprising skin matrix:
(1) component A is sequentially added into emulsifying pot, opens stirring (rotating speed 500rpm) and be warming up to 85 DEG C, be incubated 20min;
(2) open emulsifying pot outer circulation homogenizing 3min (speed is 2000rpm), be then kept stirring for that (rotating speed is 500rpm), cooling water temperature is opened;
(3) it is cooled to 40 DEG C, adds B component and component C, stirring 15min (rotating speed is 500rpm), 200 mesh filter-cloth filterings Discharging, obtains comprising the astringent of skin matrix.
Embodiment 2
1, the preparation method of a kind of skin matrix with senile-resistant efficacy, concretely comprises the following steps:
(1) open stirring, under the conditions of 50 DEG C, 2 weight portion polyglutamic acids be slowly added in the water of 26.97 weight portions, It is heated to 85 DEG C, is incubated 30min, is subsequently cooled to 40 DEG C, obtains polyglutamic acid solution;
(2) 0.03 weight portion tetrahydrochysene piperine is added in 3 parts by weight of propylene glycol, be heated with stirring to 60 DEG C, to be dissolved complete Complete to transparent, obtain the propylene glycol solution of tetrahydrochysene piperine;
(3) 12 weight portion Fructus Vitis viniferaes (VITIS VINIFERA) seed extract, 17 weight portion cocoas (THEOBROMA CACAO) The propylene glycol of the tetrahydrochysene piperine of extract, 22 weight portion elastin hydrolysis, 17 weight portion Pollen pini thunbergii dew extracts and step (2) Solution adds in the polyglutamic acid solution of step (1), stirs 15min, stirs speed for 400rpm, low speed homogenizing 2min, homogenizing speed For 1500rpm, 200 mesh filter-cloth filterings, discharging, i.e. obtain the skin matrix with senile-resistant efficacy.
2, a kind of astringent comprising skin matrix, is made up of following component by mass percentage:
Component A: deionized water 68.8%, glycerol 4.0%, propylene glycol 7.0%, 1,2-pentanediol 5.0%, carbomer 0.1%;
B component: above-mentioned skin matrix 15%;
Component C: triethanolamine 0.1%.
A kind of preparation method of the astringent comprising skin matrix:
(1) component A is sequentially added into emulsifying pot, opens stirring (rotating speed 500rpm) and be warming up to 85 DEG C, be incubated 20min;
(2) open emulsifying pot outer circulation homogenizing 3min (speed is 2000rpm), be then kept stirring for that (rotating speed is 500rpm), cooling water temperature is opened;
(3) it is cooled to 40 DEG C, adds B component and component C, stirring 15min (rotating speed is 500rpm), 200 mesh filter-cloth filterings Discharging, obtains comprising the astringent of skin matrix.
Embodiment 3
1, the preparation method of a kind of skin matrix with senile-resistant efficacy, concretely comprises the following steps:
(1) open stirring, under the conditions of 50 DEG C, 3 weight portion polyglutamic acids be slowly added in the water of 13.97 weight portions, It is heated to 85 DEG C, is incubated 30min, is subsequently cooled to 40 DEG C, obtains polyglutamic acid solution;
(2) 0.03 weight portion tetrahydrochysene piperine is added in 3 parts by weight of propylene glycol, be heated with stirring to 60 DEG C, to be dissolved complete Complete to transparent, obtain the propylene glycol solution of tetrahydrochysene piperine;
(3) by 15 weight portion Fructus Vitis viniferaes (VITIS VINIFERA) seed extract, 20 weight portion cocoa (THEOBROMA CACAO) extract, 25 weight portion elastin hydrolysis, 20 weight portion Pollen pini thunbergiis dew extracts and the tetrahydrochysene piperines of step (2) Propylene glycol solution adds in the polyglutamic acid solution of step (1), stirs 15min, and stirring speed is 400rpm, low speed homogenizing 2min, all Matter speed is 1500rpm, 200 mesh filter-cloth filterings, discharging, i.e. obtains the skin matrix with senile-resistant efficacy.
2, a kind of astringent comprising skin matrix, is made up of following component by mass percentage:
Component A: deionized water 68.8%, glycerol 4.0%, propylene glycol 7.0%, 1,2-pentanediol 5.0%, carbomer 0.1%;
B component: above-mentioned skin matrix 15%;
Component C: triethanolamine 0.1%.
A kind of preparation method of the astringent comprising skin matrix:
(1) component A is sequentially added into emulsifying pot, opens stirring (rotating speed 500rpm) and be warming up to 85 DEG C, be incubated 20min;
(2) open emulsifying pot outer circulation homogenizing 3min (speed is 2000rpm), be then kept stirring for that (rotating speed is 500rpm), cooling water temperature is opened;
(3) it is cooled to 40 DEG C, adds B component and component C, stirring 15min (rotating speed is 500rpm), 200 mesh filter-cloth filterings Discharging, obtains comprising the astringent of skin matrix.
Comparative example a:
A kind of skin matrix with senile-resistant efficacy, is made up of following component by mass percentage: 15% Fructus Vitis viniferae (VITIS VINIFERA) seed extract, 25% elastin hydrolysis, 20% Pollen pini thunbergii dew extract, 3% polyglutamic acid, 3% the third Glycol, 0.03% tetrahydrochysene piperine and the deionized water of surplus;Its preparation method is with the preparation side of skin matrix in embodiment 3 Method;
A kind of astringent (i.e. comprising the cosmetics of skin matrix) comprising skin matrix, by following by mass percentage Composition: each component and content are with the astringent comprising skin matrix in embodiment 3;Its preparation method is changed with in embodiment 3 The preparation method of adornment water.
Comparative example b:
A kind of skin matrix with senile-resistant efficacy, is made up of the following component counted by weight: 20% cocoa (THEOBROMA CACAO) extract, 25% elastin hydrolysis, 20% Pollen pini thunbergii dew extract, 3% polyglutamic acid, 3% the third two Alcohol, 0.03% tetrahydrochysene piperine and the deionized water of surplus;Its preparation method is with the preparation side of skin matrix in embodiment 3 Method;
A kind of astringent (i.e. comprising the cosmetics of skin matrix) comprising skin matrix, by following by mass percentage Composition: each component and content are with the astringent comprising skin matrix in embodiment 3;Its preparation method is changed with in embodiment 3 The preparation method of adornment water.
Comparative example c:
A kind of skin matrix with senile-resistant efficacy, is made up of the following component counted by weight: 15% Fructus Vitis viniferae (VITIS VINIFERA) seed extract, 20% cocoa (THEOBROMA CACAO) extract, 20% Pollen pini thunbergii dew extract, 3% Polyglutamic acid, 3% propylene glycol, 0.03% tetrahydrochysene piperine and the deionized water of surplus;Its preparation method protects with in embodiment 3 The preparation method of skin substrate;
A kind of astringent (i.e. comprising the cosmetics of skin matrix) comprising skin matrix, by following by mass percentage Composition: each component and content are with the astringent comprising skin matrix in embodiment 3;Its preparation method is changed with in embodiment 3 The preparation method of adornment water.
Comparative example d:
A kind of skin matrix with senile-resistant efficacy, is made up of the following component counted by weight: 15% Fructus Vitis viniferae (VITIS VINIFERA) seed extract, 20% cocoa (THEOBROMA CACAO) extract, 25% elastin hydrolysis, 3% Polyglutamic acid, 3% propylene glycol, 0.03% tetrahydrochysene piperine and the deionized water of surplus;Its preparation method protects with in embodiment 3 The preparation method of skin substrate;
A kind of astringent (i.e. comprising the cosmetics of skin matrix) comprising skin matrix, by following by mass percentage Composition: each component and content are with the astringent comprising skin matrix in embodiment 3;Its preparation method is changed with in embodiment 3 The preparation method of adornment water.
Comparative example e:
A kind of skin matrix with senile-resistant efficacy, is made up of the following component counted by weight: 15% Fructus Vitis viniferae (VITIS VINIFERA) seed extract, 20% cocoa (THEOBROMA CACAO) extract, 25% elastin hydrolysis, 20% Pollen pini thunbergii dew extract, 3% polyglutamic acid and the deionized water of surplus;Its preparation method is with skin matrix in embodiment 3 Preparation method;
A kind of astringent (i.e. comprising the cosmetics of skin matrix) comprising skin matrix, by following by mass percentage Composition: each component and content are with the astringent comprising skin matrix in embodiment 3;Its preparation method is changed with in embodiment 3 The preparation method of adornment water.
Comparative example f:
A kind of skin matrix with senile-resistant efficacy, is made up of the following component counted by weight: 15% Semen Vitis viniferae Extract, 85% deionized water;Its preparation method is with the preparation method of skin matrix in embodiment 3;
A kind of astringent (i.e. comprising the cosmetics of skin matrix) comprising skin matrix, by following by mass percentage Composition: each component and content are with the astringent comprising skin matrix in embodiment 3;Its preparation method is changed with in embodiment 3 The preparation method of adornment water.
Comparative example g:
A kind of skin matrix with senile-resistant efficacy, is made up of the following component counted by weight: 20% cocoa carries Take thing, 80% deionized water;Its preparation method is with the preparation method of skin matrix in embodiment 3;
A kind of astringent (i.e. comprising the cosmetics of skin matrix) comprising skin matrix, by following by mass percentage Composition: each component and content are with the astringent comprising skin matrix in embodiment 3;Its preparation method is changed with in embodiment 3 The preparation method of adornment water.
Comparative example h:
A kind of skin matrix with senile-resistant efficacy, is formed 25% Semen Vitis viniferae by the following component counted by weight and carries Take thing, 75% deionized water;Its preparation method is with the preparation method of skin matrix in embodiment 3;
A kind of astringent (i.e. comprising the cosmetics of skin matrix) comprising skin matrix, by following by mass percentage Composition: each component and content are with the astringent comprising skin matrix in embodiment 3;Its preparation method is changed with in embodiment 3 The preparation method of adornment water.
Comparative example i:
A kind of skin matrix with senile-resistant efficacy, is made up of the following component counted by weight: 15% Pollen pini thunbergii dew Extract, 85% deionized water;Its preparation method is with the preparation method of skin matrix in embodiment 3;
A kind of astringent (i.e. comprising the cosmetics of skin matrix) comprising skin matrix, by following by mass percentage Composition: each component and content are with the astringent comprising skin matrix in embodiment 3;Its preparation method is changed with in embodiment 3 The preparation method of adornment water.
A kind of astringent (i.e. comprising the cosmetics of skin matrix) trial effect test comprising skin matrix:
Tested crowd: 80 adult female volunteers, the age is between 30-40 one full year of life;
Test method: every day uses the skin matrix of embodiment 1-3, embodiment 1-3 to prepare at face after face cleaning sooner or later Skin matrix prepared by astringent and comparative example a-i and astringent;With VISIA-CR (face after persistently using 2 weeks and 4 weeks Portion's skin image analyser), measure skin pattern change, the degree of depth of this technology evaluation wrinkle and length and reduce degree, its test Result is as shown in table 1;Use skinanalysis apparatus (Derma-Expert MC760) that both sides cheek is carried out skin elasticity test, its Test result is as shown in table 2.
Table 1 skin pattern situation of change
Skin elasticity is tested:
Table 2 skin elasticity situation of change
From test result it can be seen that the effect of astringent prepared by embodiment 3 is best, skin surface wrinkle decrement At most, average wrinkle volume reduction is most, skin elasticity is worth increments maximum;Whole composition is with the addition of in skin matrix (Fructus Vitis viniferae (VITIS VINIFERA) seed extract, cocoa (THEOBROMA CACAO) extract, elastin hydrolysis, Pollen pini thunbergii dew Extract, polyglutamic acid, propylene glycol, tetrahydrochysene piperine and deionized water) the embodiment 1-3 effect effect than comparative example a-i Fruit to get well;And the effect of the astringent of embodiment 3 preparation is better than comparative example's a, g effect sum;It is better than comparative example B, f effect sum;It is better than comparative example's c, h effect sum;It is better than comparative example's d, i effect sum.Therefore, described skin protection In substrate, each composition has the most collaborative effect and obtains preferable effect in terms of defying age wrinkle removal, increase skin elasticity.
Above-described embodiment is the present invention preferably embodiment, but embodiments of the present invention are not by above-described embodiment Limit, the change made under other any spirit without departing from the present invention and principle, modify, substitute, combine, simplify, All should be the substitute mode of equivalence, within being included in protection scope of the present invention.

Claims (10)

1. a skin matrix with senile-resistant efficacy, it is characterised in that: it is made up of following component by mass percentage:
2. there is according to claims 1 preparation method of the skin matrix of senile-resistant efficacy, it is characterised in that: include with Lower step:
(1) open stirring, under the conditions of 40~50 DEG C, polyglutamic acid is slowly added in water, is heated to 85~90 DEG C, insulation, Then cool down, obtain polyglutamic aqueous acid;
(2) tetrahydrochysene piperine is added in propylene glycol, heated and stirred, to be dissolved completely to transparent, obtain the third of tetrahydrochysene piperine Glycol solution;
(3) by Semen Vitis viniferae extract, cocoa extract, elastin hydrolysis, Pollen pini thunbergii dew extract and the tetrahydrochysene Fructus Piperis of step (2) In the propylene glycol solution of alkali, add in the polyglutamic aqueous acid of step (1), stirring, low speed homogenizing, filters, discharging, obtains There is the skin matrix of senile-resistant efficacy.
The most according to claim 2, there is the preparation method of the skin matrix of senile-resistant efficacy, it is characterised in that: step (3) Described in stirring speed be 400~500rpm;Described low speed homogenizing is 1000~1500rpm.
The most according to claim 2, there is the preparation method of the skin matrix of senile-resistant efficacy, it is characterised in that: step (1) Described in temperature retention time be 20~30min, the temperature of cooling is 35 DEG C~40 DEG C.
The most according to claim 2, there is the preparation method of the skin matrix of senile-resistant efficacy, it is characterised in that: step (2) Described in heating temperature be 60 DEG C~70 DEG C.
The most according to claim 2, there is the preparation method of the skin matrix of senile-resistant efficacy, it is characterised in that: step (3) Described in stirring time be 10~15min, the time of described low speed homogenizing is 2~3min.
The most according to claim 1, there is the skin matrix of senile-resistant efficacy, it is characterised in that: described skin matrix is transparent Liquid.
8. cosmetics, comprise the skin matrix described in claim 1 with senile-resistant efficacy.
Cosmetics the most according to claim 8, it is characterised in that the weight of the skin matrix described in: with senile-resistant efficacy contains Amount is 15%~35%.
Cosmetics the most according to claim 8 or claim 9, it is characterised in that: main by following component group by mass percentage Become:
Component A: glycerol 2.0%~8%, propylene glycol 5.0%~10.0%, 1,2-pentanediol 4.0%~6.0%, carbomer 0.05%~0.25%, deionized water surplus;
B component: the above-mentioned skin matrix 15%~35% with senile-resistant efficacy;
Component C: triethanolamine 0.05%~0.25%.
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