CN111388399A - Whitening anti-aging facial cleanser and preparation method thereof - Google Patents

Whitening anti-aging facial cleanser and preparation method thereof Download PDF

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CN111388399A
CN111388399A CN202010416339.5A CN202010416339A CN111388399A CN 111388399 A CN111388399 A CN 111388399A CN 202010416339 A CN202010416339 A CN 202010416339A CN 111388399 A CN111388399 A CN 111388399A
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parts
extract
whitening
facial cleanser
skin
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朱成光
李娜
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Jiangsu Hankong Intelligent Technology Co ltd
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Jiangsu Hankong Intelligent Technology Co ltd
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    • A61K8/988Honey; Royal jelly, Propolis
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    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
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    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
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Abstract

The invention belongs to the technical field of cosmetics, and particularly relates to a whitening anti-aging facial cleanser and a preparation method thereof. The whitening anti-aging facial cleanser comprises the following raw materials in parts by weight: 20-30 parts of lauric acid, 20-40 parts of glycerol, 3-5 parts of hyaluronic acid, 1-3 parts of ginkgo leaf extract, 2-4 parts of jasmine extract, 2-3 parts of liquorice extract, 1-2 parts of moringa oleifera leaf extract, 1-2 parts of ophiopogon root extract, 2-3 parts of propolis extract, 3-5 parts of pearl powder, 1-3 parts of anti-wrinkle putty activator and 30-40 parts of water. The whitening anti-aging facial cleanser plays a role in inhibiting melanin generation and transfer in a combined and synergistic manner, can maintain normal physiological metabolism and functions of skin, inhibits the generation of melanin and lightens the skin color through multiple ways, and has a safe and effective whitening effect; and can effectively improve the elasticity of the skin and delay the aging of the skin; in addition, the whitening anti-aging facial cleanser contains various plant essential factors, deeply maintains the skin and relieves wrinkles.

Description

Whitening anti-aging facial cleanser and preparation method thereof
Technical Field
The invention belongs to the technical field of cosmetics, and particularly relates to a whitening anti-aging facial cleanser and a preparation method thereof.
Background
At present, a plurality of face cleansers exist in the market, and have the functions of cleaning, whitening, controlling oil or removing acnes, but most of the face cleansers are synthesized by adopting chemical components, and have the defects of easy skin allergy, difficult skin absorption, insignificant long-term use effect and the like. In addition, the existing facial cleanser product has multiple effects, but generally only has the functions of cleaning and moisturizing, and the effects of repairing skin, removing wrinkles and resisting aging are not obvious. Therefore, there is a need for a cleanser with high safety and excellent effects of cleansing, whitening, repairing skin, removing wrinkles, resisting aging, and the like.
Disclosure of Invention
Based on the prior art, the invention aims to provide the whitening anti-aging facial cleanser and the preparation method thereof, so as to solve the technical problems that the existing facial cleanser is easy to cause anaphylactic reaction and the like, and the effects of repairing skin, removing wrinkles and resisting aging are not obvious.
In order to achieve the above purpose, the invention adopts the technical scheme that: the whitening anti-aging facial cleanser comprises the following raw materials in parts by weight: 20-30 parts of lauric acid, 20-40 parts of glycerol, 3-5 parts of hyaluronic acid, 1-3 parts of ginkgo leaf extract, 2-4 parts of jasmine extract, 2-3 parts of liquorice extract, 1-2 parts of moringa oleifera leaf extract, 1-2 parts of ophiopogon root extract, 2-3 parts of propolis extract, 3-5 parts of pearl powder, 1-3 parts of anti-wrinkle putty activator and 30-40 parts of water.
Preferably, the whitening and anti-aging facial cleanser comprises the following raw materials in parts by weight: 25 parts of lauric acid, 30 parts of glycerol, 4 parts of hyaluronic acid, 2 parts of ginkgo leaf extract, 3 parts of jasmine extract, 2 parts of licorice extract, 2 parts of moringa leaf extract, 2 parts of ophiopogon root extract, 3 parts of propolis extract, 4 parts of pearl powder, 2 parts of antioxidant, 2 parts of anti-greasy activator and 35 parts of deionized water.
Preferably, the anti-greasy activator is a mixture of polysaccharide/hydrolyzed collagen and red wine polyphenols.
Preferably, the raw material composition of the whitening and anti-aging facial cleanser further comprises 2-5 parts by mass of vitamin C or derivatives thereof.
Preferably, the raw material composition of the whitening and anti-aging facial cleanser also comprises 1-3 parts by mass of vitamin B3
Preferably, the raw material composition of the whitening and anti-aging facial cleanser also comprises 0.5-1 part by mass of prednisone.
The invention also provides a preparation method of the whitening anti-aging facial cleanser, which comprises the following steps:
step 1): preparing raw materials according to the mass part ratio;
step 2): mixing lauric acid and glycerol with a stirring pot, stirring and heating to 80-90 ℃ to completely dissolve the lauric acid and the glycerol, and cooling to 30-40 ℃;
step 3): adding hyaluronic acid and partial deionized water into a reactor, and stirring to completely dissolve the hyaluronic acid;
step 4): adding dissolved lauric acid and glycerol into a reactor, sequentially adding folium Ginkgo extract, flos Jasmini sambac extract, Glycyrrhrizae radix extract, Moringa oleifera leaf extract, radix Ophiopogonis extract, propolis extract, the rest part of deionized water, Margarita powder, antioxidant and anti-wrinkle putty activator, stirring, and bottling.
The whitening anti-aging facial cleanser comprises a plurality of groups of functional components, wherein hyaluronic acid is added to form an unclosed water-locking mucous membrane layer on the epidermis, the moisture degree of the epidermis is kept, a water-oil barrier membrane on the epidermis is formed, and the further dry feeling of the skin is reduced.
In addition, vitamin C and vitamin B3 can be added into the whitening and anti-aging facial cleanser component, wherein the vitamin C is a well-known skin whitening agent and can promote the synthesis of ossein and inhibit the peroxidation of lipid compounds, and the main action mechanism of the whitening and anti-aging facial cleanser component is as follows: reducing the dopachrome into colorless dopachrome, inhibiting the generation of melanin, and enabling the dark skin to recover white and tender; has effects in scavenging free radicals, inhibiting peroxidation and aging of lipid compounds, especially delaying and neutralizing free radical injury caused by ultraviolet, and preventing skin blackening; the recovery and the generation of skin elastin and collagen are promoted, the skin is kept and the youth activity is recovered, and the anti-aging effect is achieved. Vitamin B3Can promote cellular energy metabolism, is a component required for lipid metabolism, oxidation of tissue respiration and glycogenolysis, and can affect normal respiration and metabolism of cells when the component is deficient, so that the pellagra can occur. Shows that the nicotinamide has anti-inflammatory activity, can promote DNA damage repair induced by ultraviolet rays and the like, inhibits the photocarcinogenicity of UVB radiation, and has been widely used for pellagra and has long-lasting effect in clinicDermatosis such as erythema, acne, etc. The whitening principle of niacinamide mainly comprises the following points: acts on melanin which is produced, and reduces the transfer of the melanin to surface layer cells; accelerating metabolism and promoting the exfoliation of melanocyte containing keratinocyte; promoting the synthesis of epidermal protein and improving skin texture.
In addition, for the skin with acne on the face, prednisone can be added into the whitening and anti-aging facial cleanser component, has the effects of resisting bacteria, diminishing inflammation and resisting allergy, can inhibit connective tissue hyperplasia, reduce the permeability of capillary vessel walls and cell membranes, reduce inflammatory exudation, inhibit the formation and release of histamine and other toxic substances, and effectively improve the skin with acne.
Compared with the prior art, the invention has the following beneficial effects:
the whitening anti-aging facial cleanser plays a role in inhibiting melanin generation and transfer in a combined and synergistic manner, can maintain normal physiological metabolism and functions of skin, inhibits the generation of melanin and lightens the skin color through multiple ways, and has a safe and effective whitening effect; and can effectively improve the elasticity of the skin and delay the aging of the skin; in addition, the whitening anti-aging facial cleanser contains various plant essential factors, deeply maintains the skin, relieves wrinkles, improves the skin, and improves the brightness and the whiteness of the skin.
Detailed Description
The negative ion ceramic product and the method for manufacturing the same according to the present invention will be described in further detail with reference to the following embodiments.
Example 1
The whitening anti-aging facial cleanser comprises the following raw materials in parts by weight: 25 parts of lauric acid, 30 parts of glycerol, 4 parts of hyaluronic acid, 2 parts of ginkgo leaf extract, 3 parts of jasmine extract, 2 parts of licorice extract, 2 parts of moringa leaf extract, 2 parts of ophiopogon root extract, 3 parts of propolis extract, 4 parts of pearl powder, 2 parts of antioxidant, 2 parts of red wine polyphenol and 35 parts of deionized water.
The preparation method of the whitening anti-aging facial cleanser comprises the following steps:
step 1): preparing raw materials according to the mass part ratio;
step 2): mixing lauric acid and glycerol with stirring kettle, heating to 85 deg.C under stirring to dissolve lauric acid and glycerol completely, and cooling to 35 deg.C;
step 3): adding hyaluronic acid and partial deionized water into a reactor, and stirring to completely dissolve the hyaluronic acid;
step 4): adding dissolved lauric acid and glycerol into a reactor, sequentially adding folium Ginkgo extract, flos Jasmini sambac extract, Glycyrrhrizae radix extract, Moringa oleifera leaf extract, radix Ophiopogonis extract, propolis extract, the rest part of deionized water, Margarita powder, antioxidant and anti-wrinkle putty activator, stirring, and bottling.
Example 2
The whitening anti-aging facial cleanser comprises the following raw materials in parts by weight: 20 parts of lauric acid, 40 parts of glycerol, 3 parts of hyaluronic acid, 3 parts of ginkgo leaf extract, 2 parts of jasmine extract, 3 parts of licorice extract, 1 part of moringa leaf extract, 2 parts of ophiopogon root extract, 2 parts of propolis extract, 5 parts of pearl powder, 1 part of polysaccharide/hydrolyzed collagen and 40 parts of water.
The invention also provides a preparation method of the whitening anti-aging facial cleanser, which comprises the following steps:
step 1): preparing raw materials according to the mass part ratio;
step 2): mixing lauric acid and glycerol with stirring kettle, heating to 80 deg.C under stirring to dissolve lauric acid and glycerol completely, and cooling to 30 deg.C;
step 3): adding hyaluronic acid and partial deionized water into a reactor, and stirring to completely dissolve the hyaluronic acid;
step 4): adding dissolved lauric acid and glycerol into a reactor, sequentially adding folium Ginkgo extract, flos Jasmini sambac extract, Glycyrrhrizae radix extract, Moringa oleifera leaf extract, radix Ophiopogonis extract, propolis extract, the rest part of deionized water, Margarita powder, antioxidant and anti-wrinkle putty activator, stirring, and bottling.
Example 3
The whitening anti-aging facial cleanser comprises the following raw materials in parts by weight: 30 parts of lauric acid, 20 parts of glycerol, 5 parts of hyaluronic acid, 1 part of ginkgo leaf extract, 4 parts of jasmine extract, 2 parts of liquorice extract, 2 parts of moringa leaf extract, 1 part of ophiopogon root extract, 3 parts of propolis extract, 3 parts of pearl powder, 3 parts of red wine polyphenol and 30 parts of water.
The invention also provides a preparation method of the whitening anti-aging facial cleanser, which comprises the following steps:
step 1): preparing raw materials according to the mass part ratio;
step 2): mixing lauric acid and glycerol with stirring kettle, heating to 90 deg.C under stirring to dissolve lauric acid and glycerol completely, and cooling to 40 deg.C;
step 3): adding hyaluronic acid and partial deionized water into a reactor, and stirring to completely dissolve the hyaluronic acid;
step 4): adding dissolved lauric acid and glycerol into a reactor, sequentially adding folium Ginkgo extract, flos Jasmini sambac extract, Glycyrrhrizae radix extract, Moringa oleifera leaf extract, radix Ophiopogonis extract, propolis extract, the rest part of deionized water, Margarita powder, antioxidant and anti-wrinkle putty activator, stirring, and bottling.
Example 4
The whitening anti-aging facial cleanser comprises the following raw materials in parts by weight: 25 parts of lauric acid, 30 parts of glycerol, 4 parts of hyaluronic acid, 2 parts of ginkgo leaf extract, 3 parts of jasmine extract, 2 parts of licorice extract, 2 parts of moringa leaf extract, 2 parts of ophiopogon root extract, 3 parts of propolis extract, 4 parts of pearl powder, 2 parts of antioxidant, 2 parts of red wine polyphenol, 3 parts of vitamin C and 35 parts of deionized water.
The preparation method of the whitening anti-aging facial cleanser comprises the following steps:
step 1): preparing raw materials according to the mass part ratio;
step 2): mixing lauric acid and glycerol with stirring kettle, heating to 85 deg.C under stirring to dissolve lauric acid and glycerol completely, and cooling to 35 deg.C;
step 3): adding hyaluronic acid and partial deionized water into a reactor, and stirring to completely dissolve the hyaluronic acid;
step 4): adding dissolved lauric acid and glycerol into a reactor, sequentially adding folium Ginkgo extract, flos Jasmini sambac extract, Glycyrrhrizae radix extract, Moringa oleifera leaf extract, radix Ophiopogonis extract, propolis extract, the rest part of deionized water, Margarita powder, antioxidant, anti-wrinkle putty activator and vitamin C, stirring, and bottling.
Example 5
The whitening anti-aging facial cleanser comprises the following raw materials in parts by weight: 25 parts of lauric acid, 30 parts of glycerol, 4 parts of hyaluronic acid, 2 parts of ginkgo leaf extract, 3 parts of jasmine extract, 2 parts of liquorice extract, 2 parts of moringa leaf extract, 2 parts of dwarf lilyturf tuber extract, 3 parts of propolis extract, 4 parts of pearl powder, 2 parts of antioxidant, 2 parts of red wine polyphenol and 2 parts of vitamin B by mass3And 35 parts deionized water.
The preparation method of the whitening anti-aging facial cleanser comprises the following steps:
step 1): preparing raw materials according to the mass part ratio;
step 2): mixing lauric acid and glycerol with stirring kettle, heating to 85 deg.C under stirring to dissolve lauric acid and glycerol completely, and cooling to 35 deg.C;
step 3): adding hyaluronic acid and partial deionized water into a reactor, and stirring to completely dissolve the hyaluronic acid;
step 4): adding dissolved lauric acid and glycerol into a reactor, and sequentially adding folium Ginkgo extract, flos Jasmini sambac extract, Glycyrrhrizae radix extract, Moringa oleifera leaf extract, radix Ophiopogonis extract, propolis extract, the rest part of deionized water, Margarita powder, antioxidant, anti-wrinkle putty activator and vitamin B3After stirring uniformly, bottling.
Example 6
The whitening anti-aging facial cleanser comprises the following raw materials in parts by weight: 25 parts of lauric acid, 30 parts of glycerol, 4 parts of hyaluronic acid, 2 parts of ginkgo leaf extract, 3 parts of jasmine extract, 2 parts of licorice extract, 2 parts of moringa leaf extract, 2 parts of ophiopogon root extract, 3 parts of propolis extract, 4 parts of pearl powder, 2 parts of antioxidant, 2 parts of red wine polyphenol, 1 part by mass of prednisone and 35 parts of deionized water.
The preparation method of the whitening anti-aging facial cleanser comprises the following steps:
step 1): preparing raw materials according to the mass part ratio;
step 2): mixing lauric acid and glycerol with stirring kettle, heating to 85 deg.C under stirring to dissolve lauric acid and glycerol completely, and cooling to 35 deg.C;
step 3): adding hyaluronic acid and partial deionized water into a reactor, and stirring to completely dissolve the hyaluronic acid;
step 4): adding dissolved lauric acid and glycerol into a reactor, sequentially adding folium Ginkgo extract, flos Jasmini sambac extract, Glycyrrhrizae radix extract, Moringa oleifera leaf extract, radix Ophiopogonis extract, propolis extract, the rest part of deionized water, Margarita powder, antioxidant, anti-wrinkle putty activator and prednisone, stirring, and bottling.
The preparation method of the plant extract comprises the steps of taking ginkgo leaves, washing off impurities, drying, crushing, sieving with a 60-80-mesh sieve to obtain coarse powder, placing the coarse powder in a supercritical carbon dioxide extraction device, adding 70-85% ethanol accounting for 30-45% of the total amount of the coarse powder by volume fraction, regulating and controlling the carbon dioxide flow to be 15-20L/h, the extraction pressure to be 15-20 MPa, the extraction temperature to be 40-60 ℃, the extraction time to be 1.5-2 h, and carrying out reduced pressure separation to obtain the jasmine extract and the licorice extract.
The preparation method of the moringa oleifera leaf extract comprises the following steps: cleaning Moringa oleifera leaves, drying, pulverizing, sieving with 80-100 mesh sieve, adding 8-12 times of ethanol with volume fraction of 50-70% of the total amount of medicinal materials, adding 1.5-3% of helicase, leaching at 38-45 deg.C for 1-2 hr, reflux extracting at 85-95 deg.C for 1-2 hr, filtering, and concentrating the filtrate under reduced pressure to obtain extract with relative density of 1.10-1.25 at 60 deg.C.
The preparation method of the moringa oleifera leaf extract comprises the following steps: washing impurities from the ophiopogon root, drying, crushing, sieving by a 60-80-mesh sieve, adding ethanol with the volume fraction of 60-80 percent, which is 6-8 times of the total weight of the medicinal materials, performing microwave extraction for 8-15 minutes at the microwave power of 240-65 ℃ and the extraction temperature of 45-65 ℃, filtering, and concentrating the filtrate under reduced pressure to obtain the extract with the relative density of 1.20-1.25 measured at the temperature of 60 ℃ to obtain the ophiopogon root extract.
The whitening and anti-aging tests were performed on the face cleansers of examples 1 to 6 and comparative examples 1 and 2, with the commercially available PECHOIN brand whitening face cleanser as comparative example 1 and the Nivea brand crystal pure whitening model as comparative example 2.
Firstly, testing a test article: whitening and anti-aging facial cleanser prepared in example 1 and comparative examples 1-2
II, data and grouping of the tested people group: 90 female test volunteers with healthy skin and no history of skin allergy, aged 35-55 years, received an average age of 35 years, randomly divided into 3 groups of 30 persons each.
Thirdly, a testing method: the skin elasticity Cotomerma MPA580 host manufactured by Courage + Khazaka, Germany (CK, Germany) was used, the probe used was a ReviscometerRV600 elastic fiber tissue test probe, and the average was taken five times. Test area: the forehead area 2cm above the middle of the eyebrow, the chin area 2cm below the middle of the lower lip, and the left and right cheek areas at the intersection of the nose tip and the pupil. Blank values R2, R5 and R7 of 30min after cleaning of the tested area are measured firstly), then the tested area is provided for the subjects to insist on using the test article every morning and evening, and the skin elasticity indexes R2, R5 and R7 values of the tested area are respectively tested after 2 weeks, 4 weeks, 6 weeks and 8 weeks (the negative pressure is constant to 450mbar in the test process).
Specification of indexes: the closer the skin elasticity indexes R2, R5, R7 are to 1, the better the elasticity of the skin.
R2=Ua/Uf;R5=Ur/Ue;R7=Ur/Uf
Uf-maximum amount of skin stretching
Ue-the amount of skin stretch at 0.1 second after a constant negative pressure is applied to the skin, positioning the amount of stretch in the elastic portion.
Ur-after negative pressure is removed, the skin will quickly recover to the original state, and the values are also divided into elastic part value Ur, namely, after negative pressure is removed for 0.1 second, the recovery value and the viscoelastic part value, or the plastic part value, of the skin.
Ua-the recovery value of the skin from the elimination of the negative pressure to the next successive test of the skin surface plus the negative pressure.
And fourthly, testing results of the whitening and anti-aging facial cleanser of each group are shown in the following tables 1 to 3.
TABLE 1
Figure BDA0002495232700000071
TABLE 2
Figure BDA0002495232700000072
TABLE 3
Figure BDA0002495232700000073
Figure BDA0002495232700000081
From the above test results, it can be seen that the skin condition of the testers using the whitening anti-aging facial cleanser prepared in examples 1 to 6 of the present application is significantly improved, the skin elasticity is enhanced, and the anti-aging effect is significant. Whereas the skin condition of the test subjects using the face cleansers of comparative examples 1 and 2 was less improved.
In addition, through the investigation of the above-mentioned testers, the skin whiteness and gloss of the testers using the whitening anti-aging facial cleanser prepared in examples 1 to 6 of this application were also greatly improved.
Finally, it should be noted that: although the present invention has been described in detail with reference to the foregoing embodiments, those skilled in the art will understand that various changes, modifications and substitutions can be made without departing from the spirit and scope of the invention as defined by the appended claims. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims (7)

1. The whitening anti-aging facial cleanser is characterized by comprising the following raw materials in parts by mass: 20-30 parts of lauric acid, 20-40 parts of glycerol, 3-5 parts of hyaluronic acid, 1-3 parts of ginkgo leaf extract, 2-4 parts of jasmine extract, 2-3 parts of liquorice extract, 1-2 parts of moringa oleifera leaf extract, 1-2 parts of ophiopogon root extract, 2-3 parts of propolis extract, 3-5 parts of pearl powder, 1-3 parts of anti-wrinkle putty activator and 30-40 parts of water.
2. The whitening and anti-aging facial cleanser according to claim 1, characterized by comprising the following raw materials in parts by mass: 25 parts of lauric acid, 30 parts of glycerol, 4 parts of hyaluronic acid, 2 parts of ginkgo leaf extract, 3 parts of jasmine extract, 2 parts of licorice extract, 2 parts of moringa leaf extract, 2 parts of ophiopogon root extract, 3 parts of propolis extract, 4 parts of pearl powder, 2 parts of antioxidant, 2 parts of anti-greasy activator and 35 parts of deionized water.
3. The whitening and anti-aging facial cleanser according to claim 1, wherein the anti-wrinkle putty activator is a mixture of polysaccharide/hydrolyzed collagen and red wine polyphenol.
4. The whitening and anti-aging facial cleanser according to claim 1, characterized in that the raw material composition further comprises 2-5 parts by mass of vitamin C or derivatives thereof.
5. The whitening and anti-aging facial cleanser according to claim 1, characterized in that the raw material composition further comprises 1-3 parts by mass of vitamin B3
6. The whitening and anti-aging facial cleanser according to claim 1, further comprising prednisone 0.5-1 parts by mass.
7. The preparation method of the whitening and anti-aging facial cleanser according to claim 1 or 2 is characterized by comprising the following steps of:
step 1): preparing raw materials according to the mass part ratio;
step 2): mixing lauric acid and glycerol with a stirring pot, stirring and heating to 80-90 ℃ to completely dissolve the lauric acid and the glycerol, and cooling to 30-40 ℃;
step 3): adding hyaluronic acid and partial deionized water into a reactor, and stirring to completely dissolve the hyaluronic acid;
step 4): adding dissolved lauric acid and glycerol into a reactor, sequentially adding folium Ginkgo extract, flos Jasmini sambac extract, Glycyrrhrizae radix extract, Moringa oleifera leaf extract, radix Ophiopogonis extract, propolis extract, the rest part of deionized water, Margarita powder, antioxidant and anti-wrinkle putty activator, stirring, and bottling.
CN202010416339.5A 2020-05-17 2020-05-17 Whitening anti-aging facial cleanser and preparation method thereof Pending CN111388399A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115414311A (en) * 2022-08-30 2022-12-02 上海中医药大学 Antioxidant and anti-wrinkle facial cleanser containing peony extract and preparation method thereof

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Publication number Priority date Publication date Assignee Title
CN105287290A (en) * 2015-11-18 2016-02-03 关美玲 Whitening and anti-aging face cleaner, and preparation method thereof
CN107320431A (en) * 2017-08-03 2017-11-07 泉州市知产茂业工业设计有限公司 A kind of skin whitening, moisturizing face cream and its preparation technology
CN107898737A (en) * 2017-11-30 2018-04-13 广州皓雨投资有限公司 A kind of skin whitening, moisturizing cosmetic composition and preparation method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105287290A (en) * 2015-11-18 2016-02-03 关美玲 Whitening and anti-aging face cleaner, and preparation method thereof
CN107320431A (en) * 2017-08-03 2017-11-07 泉州市知产茂业工业设计有限公司 A kind of skin whitening, moisturizing face cream and its preparation technology
CN107898737A (en) * 2017-11-30 2018-04-13 广州皓雨投资有限公司 A kind of skin whitening, moisturizing cosmetic composition and preparation method thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115414311A (en) * 2022-08-30 2022-12-02 上海中医药大学 Antioxidant and anti-wrinkle facial cleanser containing peony extract and preparation method thereof

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