CN106261362A - A kind of honeysuckle composition beverage with the liver protecting effect and preparation method - Google Patents
A kind of honeysuckle composition beverage with the liver protecting effect and preparation method Download PDFInfo
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- CN106261362A CN106261362A CN201610640156.5A CN201610640156A CN106261362A CN 106261362 A CN106261362 A CN 106261362A CN 201610640156 A CN201610640156 A CN 201610640156A CN 106261362 A CN106261362 A CN 106261362A
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- mung bean
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- 239000000203 mixture Substances 0.000 title claims abstract description 30
- 210000004185 liver Anatomy 0.000 title claims abstract description 20
- 238000002360 preparation method Methods 0.000 title claims abstract description 16
- 235000013361 beverage Nutrition 0.000 title claims abstract description 9
- 230000002633 protecting effect Effects 0.000 title claims abstract description 9
- 241000205585 Aquilegia canadensis Species 0.000 title claims abstract description 8
- 239000003651 drinking water Substances 0.000 claims abstract description 21
- 235000020188 drinking water Nutrition 0.000 claims abstract description 21
- ZDXPYRJPNDTMRX-UHFFFAOYSA-N glutamine Natural products OC(=O)C(N)CCC(N)=O ZDXPYRJPNDTMRX-UHFFFAOYSA-N 0.000 claims abstract description 15
- AGBQKNBQESQNJD-SSDOTTSWSA-N (R)-lipoic acid Chemical compound OC(=O)CCCC[C@@H]1CCSS1 AGBQKNBQESQNJD-SSDOTTSWSA-N 0.000 claims abstract description 13
- AGBQKNBQESQNJD-UHFFFAOYSA-N alpha-Lipoic acid Natural products OC(=O)CCCCC1CCSS1 AGBQKNBQESQNJD-UHFFFAOYSA-N 0.000 claims abstract description 13
- 235000019136 lipoic acid Nutrition 0.000 claims abstract description 13
- 229960002663 thioctic acid Drugs 0.000 claims abstract description 13
- 241000628997 Flos Species 0.000 claims abstract description 11
- 230000001954 sterilising effect Effects 0.000 claims abstract description 10
- 210000000582 semen Anatomy 0.000 claims abstract description 9
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 claims abstract description 7
- 229910052725 zinc Inorganic materials 0.000 claims abstract description 7
- 239000011701 zinc Substances 0.000 claims abstract description 7
- 238000004659 sterilization and disinfection Methods 0.000 claims abstract description 6
- 239000000463 material Substances 0.000 claims abstract description 5
- CWVRJTMFETXNAD-FWCWNIRPSA-N 3-O-Caffeoylquinic acid Natural products O[C@H]1[C@@H](O)C[C@@](O)(C(O)=O)C[C@H]1OC(=O)\C=C\C1=CC=C(O)C(O)=C1 CWVRJTMFETXNAD-FWCWNIRPSA-N 0.000 claims abstract description 4
- PZIRUHCJZBGLDY-UHFFFAOYSA-N Caffeoylquinic acid Natural products CC(CCC(=O)C(C)C1C(=O)CC2C3CC(O)C4CC(O)CCC4(C)C3CCC12C)C(=O)O PZIRUHCJZBGLDY-UHFFFAOYSA-N 0.000 claims abstract description 4
- CWVRJTMFETXNAD-KLZCAUPSSA-N Neochlorogenin-saeure Natural products O[C@H]1C[C@@](O)(C[C@@H](OC(=O)C=Cc2ccc(O)c(O)c2)[C@@H]1O)C(=O)O CWVRJTMFETXNAD-KLZCAUPSSA-N 0.000 claims abstract description 4
- CWVRJTMFETXNAD-JUHZACGLSA-N chlorogenic acid Chemical compound O[C@@H]1[C@H](O)C[C@@](O)(C(O)=O)C[C@H]1OC(=O)\C=C\C1=CC=C(O)C(O)=C1 CWVRJTMFETXNAD-JUHZACGLSA-N 0.000 claims abstract description 4
- 229940074393 chlorogenic acid Drugs 0.000 claims abstract description 4
- FFQSDFBBSXGVKF-KHSQJDLVSA-N chlorogenic acid Natural products O[C@@H]1C[C@](O)(C[C@@H](CC(=O)C=Cc2ccc(O)c(O)c2)[C@@H]1O)C(=O)O FFQSDFBBSXGVKF-KHSQJDLVSA-N 0.000 claims abstract description 4
- 235000001368 chlorogenic acid Nutrition 0.000 claims abstract description 4
- BMRSEYFENKXDIS-KLZCAUPSSA-N cis-3-O-p-coumaroylquinic acid Natural products O[C@H]1C[C@@](O)(C[C@@H](OC(=O)C=Cc2ccc(O)cc2)[C@@H]1O)C(=O)O BMRSEYFENKXDIS-KLZCAUPSSA-N 0.000 claims abstract description 4
- 240000004922 Vigna radiata Species 0.000 claims description 19
- 235000010721 Vigna radiata var radiata Nutrition 0.000 claims description 19
- 235000011469 Vigna radiata var sublobata Nutrition 0.000 claims description 19
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 19
- 239000011259 mixed solution Substances 0.000 claims description 10
- ZDXPYRJPNDTMRX-VKHMYHEASA-N L-glutamine Chemical compound OC(=O)[C@@H](N)CCC(N)=O ZDXPYRJPNDTMRX-VKHMYHEASA-N 0.000 claims description 7
- 235000004554 glutamine Nutrition 0.000 claims description 6
- 235000016804 zinc Nutrition 0.000 claims description 3
- 238000009835 boiling Methods 0.000 claims 1
- 238000003756 stirring Methods 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 5
- 239000002994 raw material Substances 0.000 abstract description 5
- 239000000126 substance Substances 0.000 abstract description 5
- 230000003647 oxidation Effects 0.000 abstract description 3
- 238000007254 oxidation reaction Methods 0.000 abstract description 3
- 230000002708 enhancing effect Effects 0.000 abstract description 2
- 230000002443 hepatoprotective effect Effects 0.000 abstract description 2
- 235000008216 herbs Nutrition 0.000 abstract description 2
- 230000010354 integration Effects 0.000 abstract description 2
- 238000004519 manufacturing process Methods 0.000 abstract description 2
- WGIWBXUNRXCYRA-UHFFFAOYSA-H trizinc;2-hydroxypropane-1,2,3-tricarboxylate Chemical compound [Zn+2].[Zn+2].[Zn+2].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O.[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O WGIWBXUNRXCYRA-UHFFFAOYSA-H 0.000 description 4
- 229940068475 zinc citrate Drugs 0.000 description 4
- 235000006076 zinc citrate Nutrition 0.000 description 4
- 239000011746 zinc citrate Substances 0.000 description 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 3
- 230000006378 damage Effects 0.000 description 3
- 239000003814 drug Substances 0.000 description 3
- 229960002743 glutamine Drugs 0.000 description 3
- 230000002440 hepatic effect Effects 0.000 description 3
- 231100000753 hepatic injury Toxicity 0.000 description 3
- 210000000056 organ Anatomy 0.000 description 3
- 210000001519 tissue Anatomy 0.000 description 3
- 206010061218 Inflammation Diseases 0.000 description 2
- 206010067125 Liver injury Diseases 0.000 description 2
- 206010048259 Zinc deficiency Diseases 0.000 description 2
- 230000004054 inflammatory process Effects 0.000 description 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 2
- 230000003859 lipid peroxidation Effects 0.000 description 2
- 230000004060 metabolic process Effects 0.000 description 2
- NWONKYPBYAMBJT-UHFFFAOYSA-L zinc sulfate Chemical compound [Zn+2].[O-]S([O-])(=O)=O NWONKYPBYAMBJT-UHFFFAOYSA-L 0.000 description 2
- 229960001763 zinc sulfate Drugs 0.000 description 2
- 229910000368 zinc sulfate Inorganic materials 0.000 description 2
- MZOFCQQQCNRIBI-VMXHOPILSA-N (3s)-4-[[(2s)-1-[[(2s)-1-[[(1s)-1-carboxy-2-hydroxyethyl]amino]-4-methyl-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-[[2-[[(2s)-2,6-diaminohexanoyl]amino]acetyl]amino]-4-oxobutanoic acid Chemical compound OC[C@@H](C(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)CCCCN MZOFCQQQCNRIBI-VMXHOPILSA-N 0.000 description 1
- 206010002198 Anaphylactic reaction Diseases 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 101710088194 Dehydrogenase Proteins 0.000 description 1
- 206010016260 Fatty acid deficiency Diseases 0.000 description 1
- 241000699670 Mus sp. Species 0.000 description 1
- 102000003945 NF-kappa B Human genes 0.000 description 1
- 108010057466 NF-kappa B Proteins 0.000 description 1
- 102100029438 Nitric oxide synthase, inducible Human genes 0.000 description 1
- 101710089543 Nitric oxide synthase, inducible Proteins 0.000 description 1
- 102000045595 Phosphoprotein Phosphatases Human genes 0.000 description 1
- 108700019535 Phosphoprotein Phosphatases Proteins 0.000 description 1
- 101710098398 Probable alanine aminotransferase, mitochondrial Proteins 0.000 description 1
- 206010063837 Reperfusion injury Diseases 0.000 description 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 description 1
- 108060008682 Tumor Necrosis Factor Proteins 0.000 description 1
- 102000000852 Tumor Necrosis Factor-alpha Human genes 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- PHRUYNFFDRXZQY-UHFFFAOYSA-N [S].C(CCCCCCC)(=O)O Chemical compound [S].C(CCCCCCC)(=O)O PHRUYNFFDRXZQY-UHFFFAOYSA-N 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 230000001476 alcoholic effect Effects 0.000 description 1
- 239000003513 alkali Substances 0.000 description 1
- 230000036783 anaphylactic response Effects 0.000 description 1
- 208000003455 anaphylaxis Diseases 0.000 description 1
- 230000003064 anti-oxidating effect Effects 0.000 description 1
- 230000006907 apoptotic process Effects 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 210000000170 cell membrane Anatomy 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 208000037976 chronic inflammation Diseases 0.000 description 1
- 208000037893 chronic inflammatory disorder Diseases 0.000 description 1
- 230000007850 degeneration Effects 0.000 description 1
- 235000004626 essential fatty acids Nutrition 0.000 description 1
- 230000004129 fatty acid metabolism Effects 0.000 description 1
- 235000013373 food additive Nutrition 0.000 description 1
- 239000002778 food additive Substances 0.000 description 1
- 235000013376 functional food Nutrition 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 229910001385 heavy metal Inorganic materials 0.000 description 1
- 230000002757 inflammatory effect Effects 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 230000035987 intoxication Effects 0.000 description 1
- 231100000566 intoxication Toxicity 0.000 description 1
- 208000012947 ischemia reperfusion injury Diseases 0.000 description 1
- 235000014655 lactic acid Nutrition 0.000 description 1
- 239000004310 lactic acid Substances 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 230000003908 liver function Effects 0.000 description 1
- 210000002311 liver mitochondria Anatomy 0.000 description 1
- 239000002207 metabolite Substances 0.000 description 1
- 230000000116 mitigating effect Effects 0.000 description 1
- 210000003470 mitochondria Anatomy 0.000 description 1
- 230000017074 necrotic cell death Effects 0.000 description 1
- 208000008338 non-alcoholic fatty liver disease Diseases 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 229940126701 oral medication Drugs 0.000 description 1
- 230000036542 oxidative stress Effects 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- -1 oxygen free radical Chemical class 0.000 description 1
- 230000036285 pathological change Effects 0.000 description 1
- 231100000915 pathological change Toxicity 0.000 description 1
- 239000000575 pesticide Substances 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 229910052717 sulfur Inorganic materials 0.000 description 1
- 239000011593 sulfur Substances 0.000 description 1
- 230000001629 suppression Effects 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 230000008359 toxicosis Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/38—Other non-alcoholic beverages
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/52—Adding ingredients
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
A kind of honeysuckle composition beverage with the liver protecting effect and preparation method, be made up of by mass fraction ratio following material: chlorogenic acid content 20 30% Flos Lonicerae extract 1,000 2000 parts；Glutamine is 100 600 parts；Thioctic acid 100 300 parts；12 parts of zinc；Semen phaseoli radiati extract 3,000 6000 parts；Drinking water 100 300 ten thousand parts；And glutamine is 1 ~ 2:1 with thioctic acid mass ratio.Above-mentioned substance is mixed in proportion, homogenizing 0.5 2 hours, 120 140 DEG C of high-temperature short-time sterilization, vacuum filling, it is cooled to room temperature.Present composition formula is simple, and the raw material of use is the material of integration of edible and medicinal herbs, has enhancing body oxidation resistance, the effect of hepatoprotective, and preparation method is simple, and production technology is simple and direct.
Description
Technical field
The invention belongs to functional food field of nutrition, relate to a kind of the liver protecting beverage and preparation method.
Background technology
In recent years, a large amount of edible due to ethanol, and food additive, chemicals and the use of agricultural and veterinary chemicals or residual
Staying, cause chemical hepatic injury to rise with alcoholic liver injury quantity, these all threaten the health of people.Liver is that medicine is dense
Collection, convert, the major organs of metabolism, especially oral drugs by i.e. entering liver after gastrointestinal absorption, the relatively blood of the concentration in liver
Height in liquid and other organs.Owing to medicine and the toxic action of metabolite or body produce anaphylaxis to medicine, to liver
Cause damage, cause hepatic tissue inflammation, show as medicamentous liver lesion.
Summary of the invention
It is an object of the invention to for existing issue, it is provided that a kind of honeysuckle composition beverage with the liver protecting effect
And preparation method thereof.
For achieving the above object, the present invention is achieved through the following technical solutions.
A kind of honeysuckle composition beverage with the liver protecting effect of the present invention, by following material by mass parts
Number is than composition: chlorogenic acid content is Flos Lonicerae extract 1000-2000 part of 20-30%；Glutamine is 100-600 part；Sulfur is pungent
Acid 100-300 part；Zinc 1-2 part；Mung bean water extract 3000-6000 part；Drinking water 100-300 ten thousand parts.And glutamine and sulfur
Octanoic acid mass ratio is 1 ~ 2:1.
The preparation method of a kind of honeysuckle composition beverage with the liver protecting effect of the present invention, by following step
Suddenly.
(1) preparation of mung bean water extract.Semen phaseoli radiati and drinking water are soaked 4-8 in the mass fraction ratio than 1:10-15
Hour, then big fire is boiled, and little fire simmers 30-60 minute, is pulled an oar by mixture, and 100-200 mesh is filtrated to get mung bean water
Extract.
(2) dissolving of active component.Flos Lonicerae extract, glutamine, thioctic acid, zinc and mung bean water extract are added
In 100000 parts of drinking waters, mix and blend is after 1-3 hour, homogenizing 0.5-2 hour.Then high-temperature short-time sterilization, sterilising temp is
120-140 DEG C, the time is 4-10s.
(3) by the mixed solution of step (2), 900000-2900000 part drinking water, mix homogeneously are added.
(4) by the mixed solution vacuum filling of step (3), vacuum is 0.04-0.05MPa.Fill temperature controls at 60-
75 DEG C, it is cooled to room temperature and gets product.
Chlorogenic acid can significantly reduce the vigor of glutamate pyruvate transaminase under chronic inflammatory disease, reduces liver mitochondrion lipid peroxidation
Degree, strengthens Mitochondria level, reduces the inflammatory mediator release such as TNF-α and NO, has hepar damnification substantially
Mitigation.
Glutamine can improve oxidation resistance by alleviating oxidative stress, lowers liver NF-kB expression inhibiting inflammation
Reaction, reduces hepatocellular apoptosis and alleviates chemical liver injury, Ischemia-reperfusion Injury in Rat and non-alcoholic fatty liver disease, thus safeguard
Liver function.
Thioctic acid reduces liver MDA content, increases SOD activity, and suppression hepatic tissue iNOS, CYP450IIEI express, and remove
Reactive oxygen free radical, alleviates lipid peroxidation injury and stable liver plasma membrane, has preferable oxidation resistance, thus protect liver
Dirty from damage.
Zinc has important effect to protein in the metabolism of fat, is one of composition of many metalloenzyme in human body,
Such as alkali phosphatase, lactic acid dehydrogenase.Organism zinc deficiency reveals similar clinical symptoms to essential fatty acid table of absence, and
Zinc deficiency aggravation essential fatty acid deficiency shape, illustrates that zinc plays important regulation effect in fatty acid metabolism.
Semen phaseoli radiati extract can reduce the content of mice serum AST and ALT, alleviates hepatocellular degeneration, degree of necrosis, alleviates
The pathological change of hepatic tissue.Liver is body most important removing toxic substances organ simultaneously, and Semen phaseoli radiati heavy metal, pesticide intoxication and its
His various alimentary toxicosis all have preferable Detoxication, and therefore Semen phaseoli radiati has important protective effect to liver.
Present composition formula is simple, and the raw material of use is the material of integration of edible and medicinal herbs, has enhancing body antioxidation energy
Power, the effect of hepatoprotective, and preparation method are simple, and production technology is simple and direct.
Detailed description of the invention
The present invention is further illustrated by the examples that follow, but the present invention is not intended to be limited thereto.
Embodiment 1.
By mass fraction than preparing raw material: Flos Lonicerae extract 1000 parts；Glutamine is 100 parts；Thioctic acid 100 parts；
Zinc citrate 10 parts, mung bean water extract 3000 parts；Drinking water 1000000 parts.
Preparation method.
(1) preparation of mung bean water extract.By Semen phaseoli radiati and drinking water in the mass fraction ratio than 1:10 soak 5 little time,
Then big fire is boiled, and little fire simmers 50 minutes, is pulled an oar by mixture, and 100 mesh filter, and are prepared as mung bean water extract.
(2) dissolving of active component.Flos Lonicerae extract, glutamine, thioctic acid, zinc citrate and mung bean water are extracted
Thing adds in 100000 parts of drinking waters, and mix and blend is after 3 hours, homogenizing 1 hour.Mixed solution carries out high-temperature short-time sterilization, goes out
Bacterium temperature is 121 DEG C, and the time is 7s.
(3) by the mixed solution of step (2), 900000 parts of drinking waters, mix homogeneously are added.
(4) mixed liquor of step (3) being carried out vacuum filling and carry out vacuum filling, vacuum is 0.04MPa.Fill temperature
Control at 65 DEG C, be cooled to room temperature and get product.
Embodiment 2.
By mass fraction than preparing raw material: Flos Lonicerae extract 1500 parts；Glutamine is 300 parts；Thioctic acid 200 parts；
3 parts of zinc sulfate, mung bean water extract 4000 parts；Drinking water 2000000 parts.
Preparation method.
(1) preparation of mung bean water extract.By Semen phaseoli radiati and drinking water in the mass fraction ratio than 1:12 soak 6 little time,
Then big fire is boiled, and little fire simmers 40 minutes, is pulled an oar by mixture, and 150 mesh filter, and are prepared as mung bean water extract.
(2) dissolving of active component.By Flos Lonicerae extract, glutamine, thioctic acid, zinc sulfate and mung bean water extract
Adding in 100000 parts of drinking waters, mix and blend is after 2 hours, homogenizing 1 hour.Mixed solution carries out high-temperature short-time sterilization, sterilizing
Temperature is 121 DEG C, and the time is 10s.
(3) by the mixed solution of step (2), 1900000 parts of drinking waters, mix homogeneously are added.
(4) mixed liquor of step (3) being carried out vacuum filling and carry out vacuum filling, vacuum is 0.05MPa.Fill temperature
Control at 70 DEG C, be cooled to room temperature and get product.
Embodiment 3.
By mass fraction than preparing raw material: Flos Lonicerae extract 2000 parts；Glutamine is 600 parts；Thioctic acid 300 parts；
Zinc citrate 11 parts, mung bean water extract 6000 parts；Drinking water 3000000 parts.
Preparation method.
(1) preparation of mung bean water extract.By Semen phaseoli radiati and drinking water in the mass fraction ratio than 1:15 soak 5 little time,
Then big fire is boiled, and little fire simmers 35 minutes, is pulled an oar by mixture, and 200 mesh filter, and are prepared as mung bean water extract.
(2) dissolving of active component.Flos Lonicerae extract, glutamine, thioctic acid, zinc citrate and mung bean water are extracted
Thing adds in 100000 parts of drinking waters, and mix and blend is after 1 hour, homogenizing 0.6 hour.Mixed solution carries out high-temperature short-time sterilization,
Sterilising temp is 125 DEG C, and the time is 6s.
(3) by the mixed solution of step (2), 2900000 parts of drinking waters, mix homogeneously are added.
(4) mixed liquor of step (3) being carried out vacuum filling and carry out vacuum filling, vacuum is 0.05MPa.Fill temperature
Control at 60 DEG C, be cooled to room temperature and get product.
Claims (2)
1. there is a honeysuckle composition beverage for the liver protecting effect, it is characterized in that being compared group by following material by mass fraction
Become: chlorogenic acid content is Flos Lonicerae extract 1000-2000 part of 20-30%；Glutamine is 100-600 part；Thioctic acid 100-
300 parts；Zinc 1-2 part；Mung bean water extract 3000-6000 part；Drinking water 100-300 ten thousand parts；And glutamine and thioctic acid matter
Amount ratio is 1 ~ 2:1.
2. the preparation method of a kind of honeysuckle composition beverage with the liver protecting effect described in claim 1, its feature
It is according to the following steps:
(1) by Semen phaseoli radiati and drinking water in the mass fraction ratio than 1:10-15 soak 4-8 little time, then big fire is boiled, and little fire is slow
Boiling 30-60 minute, pulled an oar by mixture, 100-200 mesh is filtrated to get mung bean water extract；
(2) Flos Lonicerae extract, glutamine, thioctic acid, zinc and mung bean water extract are added in 100000 parts of drinking waters, mixed
After closing stirring 1-3 hour, homogenizing 0.5-2 hour, then high-temperature short-time sterilization, sterilising temp is 120-140 DEG C, and the time is 4-
10s；
(3) by the mixed solution of step (2), 900000-2900000 part drinking water, mix homogeneously are added；
(4) by the mixed solution vacuum filling of step (3), vacuum is 0.04-0.05MPa；Fill temperature controls at 60-75
DEG C, it is cooled to room temperature and gets product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610640156.5A CN106261362A (en) | 2016-08-08 | 2016-08-08 | A kind of honeysuckle composition beverage with the liver protecting effect and preparation method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610640156.5A CN106261362A (en) | 2016-08-08 | 2016-08-08 | A kind of honeysuckle composition beverage with the liver protecting effect and preparation method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106261362A true CN106261362A (en) | 2017-01-04 |
Family
ID=57665891
Family Applications (1)
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|---|---|---|---|
| CN201610640156.5A Pending CN106261362A (en) | 2016-08-08 | 2016-08-08 | A kind of honeysuckle composition beverage with the liver protecting effect and preparation method |
Country Status (1)
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| CN (1) | CN106261362A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108077675A (en) * | 2017-12-22 | 2018-05-29 | 宁波卫生职业技术学院 | A kind of fruit drink for being used to prevent nonalcoholic fatty liver |
| CN113679751A (en) * | 2021-08-27 | 2021-11-23 | 浙江百越生物技术有限公司 | Application of extract in preparation of medicines for reducing morphine-induced hepatotoxicity |
Citations (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1360893A (en) * | 2000-12-28 | 2002-07-31 | 李孝常 | Sobering-up liver-protecting compound prepn |
| CN1385192A (en) * | 2002-06-10 | 2002-12-18 | 陈中夫 | Oral health care products using extreated mung bean juice as mother liquor and preparation method thereof |
| CN1582784A (en) * | 2003-08-21 | 2005-02-23 | 郭志忠 | Preparation method of antibacterial and antiviral honeysuckle beverage |
| CN1843397A (en) * | 2005-10-31 | 2006-10-11 | 北京万赛生物医药技术发展有限公司 | Pharmaceutical composition for treating liver disease and its preparation and application |
| CN101433312A (en) * | 2007-11-13 | 2009-05-20 | 蒋爱芳 | Health care food for protecting chemical liver damage |
| CN101669938A (en) * | 2008-09-11 | 2010-03-17 | 上海体育科学研究所 | Nutrient composition for eliminating exercise-induced fatigue |
| CN101889679A (en) * | 2009-05-20 | 2010-11-24 | 凌沛学 | Composition with disintoxicating and liver-protecting effects and application thereof in food and health-care food |
| CN102284020A (en) * | 2011-07-07 | 2011-12-21 | 中山大学 | Composite with actions of relieving alcoholism and protecting liver and preparation method and applications thereof |
| CN102846771A (en) * | 2012-07-04 | 2013-01-02 | 贵州省生物研究所 | Composition with antialcoholism and hepatoprotective effect |
| CN103006922A (en) * | 2012-12-25 | 2013-04-03 | 贵州金大地生物技术有限公司 | Composition having function of relieving alcoholism to protect liver |
| CN103271353A (en) * | 2013-05-08 | 2013-09-04 | 天津市星河系科技有限公司 | Liver protecting and health care composition and preparation method thereof |
| CN103285252A (en) * | 2012-12-27 | 2013-09-11 | 福建永生活力生物工程有限公司 | Oral liquid for alleviating hangover and protecting liver, and preparation method thereof |
| CN103404934A (en) * | 2013-08-24 | 2013-11-27 | 江苏神华药业有限公司 | Hang-over solid beverage containing glutamine and preparation method thereof |
| CN103445175A (en) * | 2013-09-17 | 2013-12-18 | 深圳万和制药有限公司 | Composition with effects of alleviating hangover and protecting liver |
| CN103479833A (en) * | 2013-09-29 | 2014-01-01 | 四川大学华西医院 | Composition for protecting liver and preparation method and application thereof |
| CN104106830A (en) * | 2014-08-04 | 2014-10-22 | 保龄宝生物股份有限公司 | Solid composition for dispelling effects of alcohol |
| CN105558721A (en) * | 2014-10-16 | 2016-05-11 | 邵雷 | Mung bean healthcare beverage |
| CN105613882A (en) * | 2016-01-07 | 2016-06-01 | 苟春虎 | Black barley hypoglycemic tea (milky tea) |
-
2016
- 2016-08-08 CN CN201610640156.5A patent/CN106261362A/en active Pending
Patent Citations (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1360893A (en) * | 2000-12-28 | 2002-07-31 | 李孝常 | Sobering-up liver-protecting compound prepn |
| CN1385192A (en) * | 2002-06-10 | 2002-12-18 | 陈中夫 | Oral health care products using extreated mung bean juice as mother liquor and preparation method thereof |
| CN1582784A (en) * | 2003-08-21 | 2005-02-23 | 郭志忠 | Preparation method of antibacterial and antiviral honeysuckle beverage |
| CN1843397A (en) * | 2005-10-31 | 2006-10-11 | 北京万赛生物医药技术发展有限公司 | Pharmaceutical composition for treating liver disease and its preparation and application |
| CN101433312A (en) * | 2007-11-13 | 2009-05-20 | 蒋爱芳 | Health care food for protecting chemical liver damage |
| CN101669938A (en) * | 2008-09-11 | 2010-03-17 | 上海体育科学研究所 | Nutrient composition for eliminating exercise-induced fatigue |
| CN101889679A (en) * | 2009-05-20 | 2010-11-24 | 凌沛学 | Composition with disintoxicating and liver-protecting effects and application thereof in food and health-care food |
| CN102284020A (en) * | 2011-07-07 | 2011-12-21 | 中山大学 | Composite with actions of relieving alcoholism and protecting liver and preparation method and applications thereof |
| CN102846771A (en) * | 2012-07-04 | 2013-01-02 | 贵州省生物研究所 | Composition with antialcoholism and hepatoprotective effect |
| CN103006922A (en) * | 2012-12-25 | 2013-04-03 | 贵州金大地生物技术有限公司 | Composition having function of relieving alcoholism to protect liver |
| CN103285252A (en) * | 2012-12-27 | 2013-09-11 | 福建永生活力生物工程有限公司 | Oral liquid for alleviating hangover and protecting liver, and preparation method thereof |
| CN103271353A (en) * | 2013-05-08 | 2013-09-04 | 天津市星河系科技有限公司 | Liver protecting and health care composition and preparation method thereof |
| CN103404934A (en) * | 2013-08-24 | 2013-11-27 | 江苏神华药业有限公司 | Hang-over solid beverage containing glutamine and preparation method thereof |
| CN103445175A (en) * | 2013-09-17 | 2013-12-18 | 深圳万和制药有限公司 | Composition with effects of alleviating hangover and protecting liver |
| CN103479833A (en) * | 2013-09-29 | 2014-01-01 | 四川大学华西医院 | Composition for protecting liver and preparation method and application thereof |
| CN104106830A (en) * | 2014-08-04 | 2014-10-22 | 保龄宝生物股份有限公司 | Solid composition for dispelling effects of alcohol |
| CN105558721A (en) * | 2014-10-16 | 2016-05-11 | 邵雷 | Mung bean healthcare beverage |
| CN105613882A (en) * | 2016-01-07 | 2016-06-01 | 苟春虎 | Black barley hypoglycemic tea (milky tea) |
Non-Patent Citations (1)
| Title |
|---|
| 王晓英，刘长姣: "金银花绿豆原汁复合饮料的生产工艺", 《食品研究与开发》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108077675A (en) * | 2017-12-22 | 2018-05-29 | 宁波卫生职业技术学院 | A kind of fruit drink for being used to prevent nonalcoholic fatty liver |
| CN113679751A (en) * | 2021-08-27 | 2021-11-23 | 浙江百越生物技术有限公司 | Application of extract in preparation of medicines for reducing morphine-induced hepatotoxicity |
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