KR20170029764A - Garlic extracts, egg yolk extracts and sulfur mixture to back out of the prevention of cardiovascular, cerebrovascular and other circulatory organ system disease, for the inclusion of active ingredients and treatment of functional foods, improvement and the manufacturing method. and Health functional food, organic sulphur (MSM)as active ingredients composition - Google Patents
Garlic extracts, egg yolk extracts and sulfur mixture to back out of the prevention of cardiovascular, cerebrovascular and other circulatory organ system disease, for the inclusion of active ingredients and treatment of functional foods, improvement and the manufacturing method. and Health functional food, organic sulphur (MSM)as active ingredients composition Download PDFInfo
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- KR20170029764A KR20170029764A KR1020150126762A KR20150126762A KR20170029764A KR 20170029764 A KR20170029764 A KR 20170029764A KR 1020150126762 A KR1020150126762 A KR 1020150126762A KR 20150126762 A KR20150126762 A KR 20150126762A KR 20170029764 A KR20170029764 A KR 20170029764A
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- egg yolk
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- A23V2250/212—Garlic
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Abstract
Description
The present invention relates to the provision of functional foods for prevention, improvement and treatment of cardiovascular cerebral blood vessels and other cardiovascular diseases including garlic extract, egg yolk extract, and sulfur mixture as an active ingredient, and a method for preparing the same.
Also, the present invention relates to a health functional food composition comprising an organic sulfur (MSM) substance-carrying function as an active ingredient.
Fat deposits, fibrous tissue (plaque), and blood clots in the blood vessels are accumulated on the inner wall of blood vessels by circulatory machines (cardiovascular, cerebrovascular, peripheral blood vessels, and arterial and venous blood vessels) It blocks my blood flow.
Thus, blood vessels of circulatory organs inside the body such as the heart and brain are cured and serious diseases are generated in the organs of the body. Diseases in which the coronary arteries become severely narrowed, particularly by cardiovascular disease, can lead to chest pain called angina pectoris by reducing blood supply to the heart muscle.
In addition, if thrombosis is caused by atherosclerosis and the narrowed coronary artery is completely obstructed, myocardial necrosis and myocardial infarction are caused to seriously damage the heart function and lead to death.
If the brain is also hardened by blood vessels, or the blood vessels are ruptured, oxygen is not supplied to the brain cells, and the brain is infarcted, leading to death.
In addition, the pressure in the blood vessels is increased and the pressure of the blood vessels is increased, resulting in a disease called hypertension. In other words, blood vessels in each of the major organs are cured and the flow of blood is blocked, resulting in serious illness due to malnutrition and oxygen deficiency.
According to the National Statistical Office, the mortality rate is 50% due to the complications caused by the circulatory vascular disease except cancer.
Accordingly, research institutes such as pharmaceutical companies around the world have studied and commercialized many substances for the prevention and treatment of vascular diseases.
However, these materials have been used for many years as a chemically synthesized material. However, they have not been positive for medical treatment for patients with circulatory system disease, and have been suffering from problems such as side effects and other causes of diseases caused by long- do.
In addition, dietary fiber, saponin, vitamin C, vitamin E, and essential amino acids can be used to treat metabolic diseases by controlling dietary nutrients. Dietary intake is recommended in the diet is used, and dietary restrictions are accompanied by mental illness, so long-term therapy is limited.
Therefore, studies have been conducted to eliminate the above-mentioned chemical synthetic substances in the food system and to solve the above problems by diet and the like, and many studies have been carried out at present.
For example, Korean Patent Registration No. 327894 discloses a composition for treating hypertension comprising a mixed extract of Samchillin and Danshen. Korean Patent Registration No. 577674 discloses a composition for treating hypertension, As an active ingredient, is disclosed as a preventive therapeutic composition for hypertension. Also, Patent Registration No. 1045551 discloses a health food for prevention and improvement of hypertension comprising, as an active ingredient, a compound derived from an extract of Rubus coreanus.
However, the above-mentioned Chinese herbal compositions are considered to be a side effect of long-term absorption of body fat and long-term effects of Chinese herbal medicine used in Chinese medicine, something to do.
Therefore, many researches on prevention, improvement, and treatment of diseases of heart, brain and other circulatory machines have been carried out overseas and domestic by using substances used in pure diet as safe foods.
As a result, the grown material is about garlic and yolk.
Each of these substances is a substance that has been absolutely required in the diet from a distant past to nutritional aspects. However, these substances have been marketed as fatigue recovery agents, but there is no product developed or improved as a blood circulation agent for improvement and prevention of cardiovascular diseases. Therefore, a lot of researches have been carried out to positively use this substance for improvement and treatment of circulatory cardiovascular diseases.
In addition, a number of research results have been published in domestic and foreign food research institutes about vascular purification functional materials and antimetabolites derived from natural food ingredients, and studies are ongoing.
However, R & D on natural products used in our daily diet is an ongoing challenge.
Under these circumstances, the inventors of the present invention have been studying substances which promote the circulation of circulatory vessels of all the organs such as cardiovascular and cerebrovascular vessels by preventing the blood vessels from hardening, decomposing and removing the deposits in the hardened blood vessel wall, The function of garlic extract, egg yolk extract and organic sulfur was found in garlic extract, which is a daily food ingredient, and the extracts of these substances were combined to increase the prevention and improvement function of circulatory vascular diseases, The present invention has been completed upon confirming that the function of the original active ingredient of herbal medicine ingredient is enhanced when the herbal extract, the egg yolk extract, and the sulfur are contained in the herbal medicine substance for improvement and treatment of the herbal medicine.
references
Pharmacological characteristics and analysis of garlic extract
Kyunggi Port / 2006 / Inhibitory effect of microbial propagation of garlic sulfur compounds
Yoon, Gun-Ae / 2007 / Exercise induced oxidative stress and garlic antioxidant activity
Chang, Byeong-Soo / 2007 / A Literature Review on the Effect of Garlic Extract on Human Skin
Yoon Kyung Lee and five others / 2008 / The relationship between functional food and soil composition of garlic
Pilochon / 2008 / Garlic and Health
Sexual use of the internet: Perceived impact on MSM's views of self and others / Nuno Nodin, Alex Carballo-
New media & society. vol. 16 no. 5, p.719-736
Effects of vegetable sulfur MSM on permanent hairs on permanent hairs. Effects of methyl sulfonyl methane MSM on hair in permanent waves
Konkuk University Graduate School, 2014.2 Master's and Doctoral Degrees (No. 107)
xiii, 108 p. ; 26 cm
Tissues and cells: MSM donor selection review / Department of Health, Advisory Committee on the Safety of Blood, Tissues and Organs
London: Department of Health, 2013
Effects of yolk sac administration on cholesterol metabolism in rats / Han, Han - Jong, Park, Sang - Oh
Journal of the Korean Oil Chemists Society. Volume 31, Issue 2, Issue No. 95 (June 2014), pp.255-264
Korea Emulsification Society
2014.06.30
Effect of dietary supplementation of egg yolk extract and high frequency management on obesity improvement / Kim, Yoo - Jung; Choi Tae Woo
Journal of Korean Society of Skin Care. Vol. 8, No. 2, Vol. 22 (May 2010) pp.263-275
Korean Society of Skin Care, 2010.05.30
It is an object of the present invention to provide a functional food composition for treating and improving cerebrovascular diseases including cardiovascular and cerebrovascular diseases composed of garlic extract, egg yolk extract, sulfur, and a method for preparing the same.
It is another object of the present invention to provide a method for the treatment and improvement of a disease caused in each organ in a human body, including circulatory diseases, among the compound of formula (I) And a method for preparing the same.
Another object of the present invention is to provide a health functional food composition composed of organic sulfur and an extract of Phellodendron chinensis as an active ingredient, the substance-carrying function of organic sulfur (MSM).
In one aspect of the present invention, there is provided a health functional food composition comprising 5-70 wt% of garlic extract, 5-70 wt% of egg yolk extract, and 5-50 wt% of sulfur, do.
Further, the present invention provides a food composition comprising 100% by weight of a mixture of extracts of a mountain orchid plant or a mixture thereof, and 1% -50% of an organic sulfur (MSM).
The present inventors have focused on garlic extract and egg yolk extract in conducting research on substances which have no side effects on the human body as human daily foods and have a preventive, remedy or therapeutic effect on heart, cerebrovascular and other circulatory diseases .
The results showed that the mixture of garlic extract, egg yolk extract and sulfur was used in hardened marmot cardiovascular system. The results showed that blood vessel cholesterol was significantly decreased, cured deposits were decreased due to lipid and thrombosis, and blood circulation was promoted , Thereby inhibiting the generation of nitric acid in the body, thereby confirming the effect of promoting the metabolism, leading to the present invention.
In addition, a composition prepared by incorporating a composition composed of garlic extract, egg yolk extract, and sulfur into a composition consisting of three kinds of ginseng, ginseng, goat ginseng, and three kinds of ginseng extracts such as Saururus chinensis, It was confirmed that there is an action to improve the composition and the therapeutic effect of the extract of the Japanese horse chestnut mushroom extract.
The efficacy of the composition comprising the organic footbath composition (MSM) in the artificial footbath composition as an inducer for rapidly moving the artificial footbath component into the body was confirmed by the fact that the original function of the artificial footbath was improved by an animal experiment.
The composition is merely an example and is not limited to the present invention.
In addition, when sulfur (s) is added to garlic extract or egg yolk extract composition by the same experiment as described above, the effect is increased to lower the LDL-cholesterol, triglyceride, It was confirmed that the expression of UCP-2 mRNA, the adiponectin mRNA expression in adipose tissue, the increase of HDL-cholesterol and the decrease of blood pressure were increased, the rigid blood vessels were changed smoothly, The results are summarized as follows.
The result is that blood pressure can be adjusted due to the disappearance of the viscous substance in the blood, thereby preventing rupture of circulatory blood vessels in the human body, improving and treating circulatory diseases, and It is an encouraging result that the prevention and improvement of the disease can be helped and the sexual function can be improved.
Further, when the composition was tested using a guinea pig model of atherosclerotic disease model in which apolipoprotein E (ApoE) gene was deficient in the effect of preventing or treating arteriosclerosis of a composition composed of garlic, egg yolk extract and sulfur, The combination of extracts, egg yolk extract and sulfur reduces the incidence of atherosclerotic lesions, decreases the total cholesterol, triglyceride and glucose concentration, decreases the LDL-cholesterol concentration, Increased AMPK activity; And suppression of FAS and SREBP-1 protein expression, inhibition of weight gain, reduction of fat cell size and lipid deposition in liver, and inhibition of liver weight gain.
Thus, it can be seen that the mixed composition of garlic extract, egg yolk extract, and sulfur can be used for the treatment or improvement of lipid-related cardiovascular diseases and liver diseases, and sexual function enhancement. It has also been found that obesity can be prevented and treated, and a mixture of sulfur (MSM) has been found to enhance this function.
In addition, it was confirmed that lactic acid was significantly reduced in the blood of the mollusk, which was obtained from the mixed composition of the garlic extract and the egg yolk extract of the present invention, compared to the composition of the present invention. Lactic acid is a by-product of degradation of glucose in an oxygen-poor environment.
The lactic acid is a substance known as a signal transducing substance for propagating cancer cells.
Scientists studying cancer have found the protein 'NDRG3' that recognizes lactic acid in cancer cells. This protein promotes angiogenesis that grows cancer cells and nourishes cancer cells. In cancer cells, cell proliferation activity is active and lactic acid is produced in large quantities. This results from the fact that lactic acid, which is a fatigue substance, is involved in cancer cell proliferation. NDRG3 protein is decomposed in an oxygen - rich environment, but if it lacks oxygen, its shape changes and breaks with binding with lactic acid.
As a result, NDRG3 protein accumulates in cancer cells that produce a lot of lactic acid, and the cancer is aggravated as the cancer cells are stimulated by the signal. That is, the fatigue material lactic acid regulates the growth of cancer cells, that is, lactic acid promotes cell division of cancer cells,
Accordingly, the composition of garlic extract, egg yolk extract and sulfur of the present invention removes naphtha in blood vessels to promote blood circulation, thereby facilitating the movement of oxygen in the blood and absorbing B1 to reduce lactic acid.
Therefore, the composition comprising the extract of graviola selected from the group consisting of garlic extract, egg yolk extract and sulfur according to the present invention was tested for cancer cell division, and it was found that the composition could inhibit the division of cancer cells by 60% And can be used for prevention and improvement of cancer diseases and can be used for immunotherapy of cancer diseases.
In addition, it was confirmed that the reproductive function and endurance of the guinea pig of the present invention were significantly improved compared with those of the guinea pig which was not consumed in the reproductive function and endurance test of the guinea pig ingesting the mixed composition of garlic extract, egg yolk extract and sulfur, It is confirmed that the function can be improved by incorporating it into a gangjeong and gangjeong preparations for sexual enhancement and treatment, which are composed of at least one kind of wild sorghum.
Accordingly, the mixture of garlic extract, egg yolk extract, and sulfur of the present invention may be added to food or a mixture of any kind of natural substances, or a herb, or a synthetic herb, to such an extent that the effect thereof is not canceled, Foods capable of preventing, alleviating, ameliorating, and treating the disease to be applied to the active substance can be produced.
The diseases mentioned above include cardiovascular, circulatory, nervous, respiratory, hematopoietic, urinary, digestive, endocrine, and immune diseases. And diseases related to musculoskeletal (bones).
For example, the mixture may be used for preventing lipid accumulation including blood cholesterol, preventing, ameliorating, and treating obesity, preventing and improving diabetes, treating, preventing and improving fatigue, promoting metabolism, , The composition can be incorporated into the composition for improvement, and the composition can be used for the various diseases.
In the term of the present invention, the garlic extract and the egg yolk extract are meant to include a low-viscosity or high-viscosity form containing the oil finely contained in water and separated from the garlic extract and the yolk extract.
In the present invention, circulatory eggs including cardiovascular blood vessels are blood vessels for moving blood, and all blood vessels formed in the body through arteries and veins including cardiovascular vessels and cerebral blood vessels.
In the term of the present invention, sulfur means pure sulfur or a compound thereof as a chemical symbol S, and means pure sulfur or a compound thereof which is not toxic.
Also, in the above-mentioned disease term, cardiovascular-related circulatory diseases means cardiovascular diseases such as coronary atherosclerosis, cerebral vasculopathy, ischemia, hypertension, arrhythmia, hyperlipidemia, myocardial infarction and varicose veins. It means all diseases.
The sulfur contained in the composition constituted by the present invention may be sulfur produced by oxidizing toxic substances by reacting mineral sulfur with indirect heat for 1 minute to 10 minutes at a temperature of 800 ° C. to 1300 ° C., or sulfur removed by toxic fermentation by microbial fermentation Can be used.
Or organic sulfur (MSM. DMSO2) obtained by synthesis from a vegetable material or synthesized without being chemically toxic.
The organic sulfur (MSM) is methyl sulfonyl methane (MSM). 1964 A study by Dr. Stanley Jacob, an American scientist, started with the invention of extracting organic sulfur from pine and other wood, It started to produce and used for plants. As technology developed, it was used for animals. It started to be used in human body and used in 120 countries. It is a substance which has been registered as a functional substance in a phytosanitary establishment and approved for use as a result of harmless to human body with no toxicity.
However, the method of using the MSM powder is limited, and the MSM powder is filled in a capsule or compressed and supplied as a tablet. Therefore, the use of organic sulfur will be limited.
Therefore, as exemplified in the present invention, the composition of the present invention includes 10-30% of the organic sulfur in the artificial fats and their mixture within a range that does not adversely affect the natural efficacy of the natural artificial fats, This is confirmed by the present invention.
The amount of MSM added to garlic extract and egg yolk extract is 1% to 70% by weight of the total weight of the composition.
In addition, the composition comprising sulfur added to the composition of the garlic extract and the egg yolk extract may be excluded from the garlic extract, or the amount of the garlic extract may be extremely small. In this case, the content of the egg yolk extract may be reversed to a large extent.
For example, garlic extract 5-10%, egg yolk extract 30% -70%, sulfur 30% -45%, garlic extract 5% -10% egg yolk extract 20-80%, sulfur 10-55% Or 10-90% of egg yolk extract, 10-90% of sulfur or 30% -90% of garlic extract, 10% -50% of sulfur, and each composition may contain some solvent.
In addition, one or more kinds of wild fauna selected from the group consisting of garlic extract, egg yolk extract, and MSM may be further added in the form of an extract, an isolate, and a sanatoria powder.
For example, one or more kinds of wild type herb extracts or their isolates, which are applied to a cardiovascular circulatory machine selected from among the above 100 kinds of garlic extract, egg yolk extract, and organic sulfur (MSM) The pulverized material may be composed as follows.
5-30% by weight of garlic extract, 5-30% by weight of egg yolk extract, 5-30% by weight of MSM, 5-30% by weight of at least one kind of wild type extract or its isolate, 5-30% % -80 wt%.
The constitutional ratio may vary depending on the formulation characteristics in which the water content in the ring-forming formulation is small and the amount of water in the liquid formulation is large.
The above-mentioned composition ratios are merely one example, and are not limited to the present invention.
Cardiovascular disease refers to a cardiovascular disease associated with lipid-related diseases. It refers to the arteries, veins and peripheral blood vessels formed in the body such as heart diseases or cerebrovascular diseases. Specifically, it refers to atherosclerosis, hypertension, myocardial infarction, stroke , Cardiovascular diseases, heart failure, heart failure, angina pectoris, endocarditis, heart valve disorders, conduction disorders, and ischemic cerebrovascular diseases, and the circulatory system is a heart involved in the circulation of blood Including, but not limited to, the occurrence of a disease in various organs of the large and small circulatory system.
Sexual function disorders are erectile dysfunction, premature ejaculation, spermatorrhea, and designation.
Garlic in the present invention is Allium scorodorpasum. It is a perennial plant cultivated in the fields of Central Asia and Europe. Alliin in garlic does not smell itself.
However, damage to garlic destroys the alliin and results in allicin and diallyl disulfide, which is a potent active ingredient.
The allin, a spicy sulfur compound of garlic, becomes an allicin by the action of an enzyme called alliinase, which has strong sterilization and antibacterial ability, It is effective for various bacterial diseases such as.
The garlic extract is one of the top 10 food products selected by the World Food Society with many functions including anticancer action, prevention of vascular diseases, and enhancement of sexual function to promote secretion of male hormone.
In addition to these functions, Garlic Extract has a hidden effect that increases the absorption of vitamin B1, which is essential for daily metabolism of stocks and carbohydrates, by 10 to 20 times.
As a result, our stock is carbohydrate. Vitamin B1 is the essential coenzyme to metabolize these carbohydrates properly. A lack of vitamin B1 and other aids can cause glucose to lose energy, make it fatigued, or be converted to fat,
Vitamin B1 also stimulates brain activity in the production and synthesis of neurotransmitters.
Sulfur compounds also have the ability to detoxify toxic substances accumulated in the body. Accordingly, a health functional food can be prepared by incorporating a toxic substance accumulated in a human body into a saururus chinensis, which is capable of detoxifying a toxic substance accumulated in the body.
In the above description, Saururus chinensis is an artificial herb that has a function of detoxifying and disturbing the encephalopathy, which is also called as a tree trunk or genitalia, and its components are decanoyl acetaldehyde, methylenonylcarbone, mithsene, lauroic aldehyde, capric aldehyde, Dihydrotestosterone, ascorbic acid, ascorbic acid, isoquercitrin, quercitrin, rainotrine, hyperperin, and the like. In the present invention, 2% -50% of the total weight of the composition may be included in the form of a water extract, a separated product, a powder or the like in order to increase the detoxifying function of sulfur by transporting the above detoxifying substance into the body by including MSM.
And important institutions such as heart and kidneys require sulfur, and bone, the skeleton of human body, can not exist without sulfur. Sulfur acts as a connection of calcium.
Sulfur is a substance that must be present in the human body at all times about 140g.
Inadequacy can lead to major diseases such as heart, kidney, skeleton (bone), metabolism, loss of cancer prevention ability, skin disease, joint disease.
As mentioned above, it is an indispensable substance in the human body, but it is a substance that can not be synthesized in the body. It is a substance that enters the body due to in vitro ingestion.
Accordingly, in the present invention, adding sulfur to the mixture of garlic extract and egg yolk extract improves the function of the mixture of the garlic extract and the yolk extract, or replenishes the sulfur required for the organs for the purpose of rapidly transferring the effective substance into the body .
In the term of the present invention, egg yolk is egg yolk and egg yolk contained in the egg. Nutrients in the cytoplasm of eggs contain proteins, fatty acids, sugars, vitamins, inorganic salts, cholesterol, carbohydrates, and amino acids.
Vitamin D, which strengthens bones and teeth, Helps to absorb calcium, Vitamin A, which strengthens eyesight and immunity, Vitamin D, which strengthens bones and teeth, It is rich in various nutrients such as zinc, which is involved in immunity and tissue growth.
The fatty acid component (in order of weight) is generally non saturated fatty acid, approximately 47% oleic acid, 16% linoleic acid. 5% palmitoleic acid, 2% alpha-linolenic acid and 23% palmitic acid as a saturated fatty acid. Stearic acid 4%. And 1% of myristic acid.
The weight of the bird egg is about 33%. Calories are about three times the amount of white calories contained in eggs.
The egg yolk is a yolk isolated from algae and is not limited to the kinds of algae. Any egg yolk isolated from algae can be used in the present invention.
In the present invention, the garlic extract and egg yolk extract are mixed with each other. The essential components of the garlic extract are sulfur compounds and oils, and the essential components of egg yolk extract are lecithin and oil.
Among the active ingredients of egg yolk, lecithin acts as a surfactant to decompose the lipid deposited and cured on the inner wall of the blood vessel along with water in the blood, and sulfur promotes blood circulation.
The lecithin contained in the egg yolk extract dissolves and decomposes the lipid and impurities which are hardened by causing surfactant to the lipid adhered to the blood wall and the water contained in the blood, and the decomposed substance is decomposed by the circulation of blood And is discharged to the outside of the body.
Thus circulation circulation of the circulating machine is smoothly circulated, thereby promoting the supply of oxygen and nutrients to each organ cell in the body, thereby maximizing the cellular metabolism.
The composition of garlic extract, egg yolk extract, sulfur composition and production method thereof, and the addition of organic sulfur (MSM) to at least one kind of wild type herb extract to treat the circulatory vascular diseases and improve function or metabolism promotion function, And the functional composition, such as improving function, cancer disease improving function, sexual function improving function, and the manufacturing method thereof will be described as follows.
Manufacturing Method 1.
1. Removing and washing the garlic epidermis as a preparation step.
2. Freezing and drying the garlic to pulverize the dried material to powder.
The pulverization process may be selected from a freeze-dried powder and a wet grinding method.
3. Grinding of garlic in the first step washing is performed by adding a certain amount of garlic to water in a range of 2 times the weight of 1-garlic weight of 5 parts by weight of garlic to induction heat of indirect heat of 80-100 degrees Celsius,
4. The step of cooling the heated garlic to a temperature of 45 degrees or less by a three-step process, and then grinding it to a state of being killed with a blender.
5. Garlic ground in step 3 or 4 step is filled in a stirrer and stirred for 2 hours to 10 hours at a temperature of 80 to 100 degrees centigrade with RPM 10-400 to evaporate water and heat until the oil is eluted into the indirect heat .
Water is added to the powder of the powdered garlic by the above two-step pulverization step as in the step 3, followed by stirring.
6. The step of cooling the garlic extract to 50 degrees C or less by evaporation of water and oil-eluted by the thermal reaction process of 5.
7. In the cooled low-point type garlic flour, the yolk is separated from the egg, and the flask is cooled. The flour is mixed with 1 to 6 parts by weight of 1 to 6 parts by weight of garlic.
8. The step of heat-treating the mixture of garlic and egg yolk heated at a temperature of 50 ° C to 110 ° C for 2 hours to 10 hours by stirring the garlic and egg yolk mixture until the oil is eluted.
9. Formulating the kneaded product with high viscosity by the above process.
The formulation is prepared by cooling the heat reactant prepared at a high viscosity and compressing it into various types of molds to form a liquid in the form of a tablet or a diluent by liquefaction.
Processes and methods for containing the extract or the separated product or the powder of sulfur or artichoke in the above manufacturing process are as follows.
1. A method for dissolving sulfur in a diluent in step 3 of the above process to impregnate the garlic into the sulfur-dissolving solution and heat it to pulverize the heated garlic containing the sulfur lysate to make it liquid.
2, or in the above step 5, garlic extract containing sulfur is thermally reacted with garlic extract.
3. In the process of step 7, when egg yolk is contained in the garlic extract which is thermally reacted with the step 5, sulfur is added together with egg yolk to cause a thermal reaction.
In any of the above steps, the sulfur or the raw material may be included in the process.
In the above description, the Sanayaka extract means nutritional and pharmaceutical substances for prevention, improvement and treatment of diseases.
In the above-described manufacturing process, the artificial sweet potato may be included as in the sulfur mixing method.
In the process of the present invention, sulfur may be included in the first or second manufacturing process. The step of incorporating the sulfur is not limited, none.
Sulfur is a mineral sulfur which is heat-reacted to a high temperature of 1,000 degrees Celsius or more to oxidize toxic substances to detoxified sulfur, or mineral sulfur which is detoxified by enzymatic action. Or sulfur (MSM) synthesized in chemical structures such as sulfur extracted from natural plants or sulfur extracted from natural plants.
Organic sulfur is preferred for adding the sulfur.
The organic sulfur is DMSO2.
DMSO2 is dimethylsulfonium methane (MSM).
Another object of the present invention is to increase the function of the artificial kidney by incorporating organic sulfur into the artificial hybrid mixture.
In the present invention, the term "sanayaso" refers to a natural or artificial cultivated plant, tree, or sow plant produced from an acid and a base (plain), and the sanayashi extract means a plant of the human body including the nervous system, respiratory system, hematopoietic blood system, Refers to a water extract, a solvent extraction extract and a dried dry powder of a mountain sole, including substances acting on diseases of one or more organs of an organ, an endocrine system, an immune system, and an anti-inflammatory system.
Examples of the sanayas added to the composition of the present invention include those containing at least one selected from among three kinds of organic ginseng, ginseng, ginseng and wild ginseng, organic foods containing the Saururus chinensis, external preparations for skin, Or a composition for external application for skin, or a tonic composition including a health food containing Sasa, a Sanshi leaflet or a nightstand, and the like.
Or the composition may also be included in the detergent composition.
For example, 10% by weight of MSM may be added to a mixture of ginseng, sorghum, Saururus chinensis, Bacillus subtilis, etc., which are used as general health functional food raw materials.
At this time, the amount of the organic sulfur (MSM) added may be 0.5% -50%, more preferably 0.8% -30% by weight, and more specifically 01% -25% by weight of the total weight of the composition.
Examples of the present invention include Chinese herbal medicine (Korean name ginseng Yangyang tang) which is prepared by giving priority to the efficacy of ginseng (ginseng, wild ginseng, ginseng ginseng) among Korean herbal medicines, such as ginseng, hwanggi, , Ginseng root, matured ginseng, bamboo shoots, omija, grassland, and vinegar can be prepared by adding 5-10% of organic sulfur to the total weight of the composition.
In another example, MSM 2% -15% is added to a mixture of 10-30 wt.% Goat's ginseng selected from ginseng, 10-50 wt.% Saururus and 10-50 wt. You may.
In another example, a cleaning agent may be prepared by adding 0.5 to 10% by weight of MSM to 100% of the total weight of the functional grouping selected from the group of Sanayasochae including the Saururus chinensis,
The above examples are merely one example, and the present invention is not limited to the present invention. MSM may be added to a mixture of any one kind of sanatoria or sanayasu to form a composition for external application, detergent and food.
In the above description, the sanayaka contains the herb of oriental medicine.
In the present invention, the addition of MSM to the composition is added for the purpose of rapidly transferring the active substance of the field sweetener into the body and for the purpose of increasing the sulfur content or the sulfur content.
According to the composition and the preparation method of the present invention, it is possible to rapidly deliver an effective substance of a composition containing a compound of the present invention to the body and to remove impurities deposited in the circulatory machinery vessel including cardiovascular and cerebral blood vessels The blood vessels are made flexible, the effect of promoting blood circulation, the effect of rapidly treating the heart, the cardiovascular circulatory system disease, and the pain relieving effect.
Hereinafter, the present invention will be described in more detail with reference to the following embodiments.
These examples are only for illustrating the present invention, and the scope of the present invention is not limited by these examples.
1. Remove 800 g of garlic from the skin and wash.
2. Add 500 ml-1500 ml of water to the washed garlic, heat it at 90 ° C for 10 minutes and cool.
Or after washing and freeze drying to pulverize powder.
In the above 2, the water of the mountainous basin water may be contained in place of water to be heated.
3. The cooled garlic of the above 2 is crushed to form fine particles.
4. The pulverized material is put into a thermal reactor and reacted for more than 2 hours at indirect temperature of 80 ° C to 95 ° C to evaporate water.
5. Prepare dough-like reactants with water evaporation and oil-eluted viscosity, and cool them to below 50 ° C.
6. Egg yolk is separated from 10 eggs and put into the dough-shaped garlic heated by the above-mentioned 5 steps, and the water is evaporated by reacting at a temperature of 80 ° C to 95 ° C for 2 hours or more. When the oil begins to elute in the egg yolk, Lt; / RTI >
7. The above prepared reaction product is compression molded into a liquid form, a ring form, or other form and formulated.
Process to include sulfur (MSM).
In each of the above steps, 400 g of MSM was dissolved in water in two steps, and garlic was added to the water to effect a thermal reaction.
Or water is added thereto, and the garlic is pulverized. MSM is added to the pulverized garlic juice to cause a thermal reaction. Or the MSM is put in a state of viscosity during the thermal reaction.
Or inject MSM during the formulation process.
The method of incorporating MSM in the present invention can be added in any process without limitation of the addition timing of MSM.
In the present invention, the method of adding the extract or mixture thereof to the thermal reaction product of garlic and egg yolk is the same as that of MSM.
A high viscosity composition having a composition of about 300 g of MSM, about 300 g of garlic extract, about 300 g of egg yolk extract and 0.1 to 2 wt% of water was prepared at a total weight of about 1 kg produced in the above process.
About 2000g of water was added to about 500g of the high viscosity composition in 1kg of the composition prepared in the above process and stirred to prepare about 2500ml of a liquid composition. The above-mentioned water can be added as a solvent in place of water, in which a water-extracted mixture of a mixture of at least one species selected from the family of Sanjayaka.
500 g of the 1 kg high-viscosity composition prepared in the above process was prepared as a ring.
The present invention relates to a method for manufacturing a pancreas, comprising the steps of: (a) providing a pancreas solution containing the active substance acting on the cardiovascular circulatory system during the pancreatectomy; Among the herd consisting of Mokmun-dong, gold-skein, and raw paper, Yongguk, the loser, Hojangun, Bongryeong, 100 g of sulfur was added to 400 g of the powder composition consisting of 100 g of the selected hay fever, and 500 g of the composition was prepared.
Sanayasu can be selected from water extracts, isolates and powders and used.
In order to investigate the transportability of the active ingredients of MSM containing the MSM, MSM 01g was added to 30ml of water extract of gosam to prepare MSM mixed liquid by adding some sugar.
In order to confirm the function of enhancing the efficacy of the active ingredient of Sanjia yezoensis, which is formed by incorporating MSM into a composition comprising at least one selected from among Sanayaka herd,
In addition, 300g of MSM was added to the ginseng phytosanic composition, which is a herbal medicine prescription composed of ginseng, seishi, shouho, crust, heaven, ganghwam, And compressed to prepare 300 pieces of 1000 mg tablets.
450 g of MSM was added to a mixture of 60 g of ginseng used as a general health functional food raw material, 60 g of Sosungcho, 110 g of Saururus chinensis, 110 g of Bacillus subtilis, and 10 g of mung bean to prepare 450 g of a cyclic form.
2g, 2g, 2g, 2g, 5g, 10g, and 1g of horn extract of selected wild flowers from cardiovascular herbaceous plants applied to cardiovascular disease improving and therapeutic functional composition composed of 200g of garlic extract, 500g of egg yolk extract and 100g of MSM A composition of 870 g of the composition in the form of a ring was prepared by adding 50 g (including solvent)
1,000 ml of a liquid composition was prepared by adding 600 ml of water extract extracted from a mixture of 300 g of garlic extract, 20 g of egg yolk extract, 100 g of MSM, 10 g of ginseng selected from Sanayasochae herb, 50 g of Saururus oryzae, 20 g of fennel root, 5 g of dandelion, .
1500ml of a mixture water extract of a mixture of 200g of yellow radish, 50g of red ginseng, 20g of red ginseng and 20g of red ginseng was added to a mixture of two kinds of mixture composed of 1000g of garlic extract and 1000g of egg yolk extract and 1000g of egg yolk extract and 1000g of MSM to prepare a high viscosity composition 2300 g of a high viscosity composition was prepared and formulated into a ring.
Each of the compositions prepared according to the above-described examples was tested in an animal experiment and a human body as described below to confirm its effect.
Experiment 1.
After administration of norepinephrine to two married rats to induce vasoconstriction,
One of the products of Example 2 was administered to two rats for the purpose of comparison, 10 ml of the composition prepared according to the examples in the experimental rats, 3 ml of the ginseng extract except for garlic and egg yolk and sulfur was administered orally to the control rats Respectively.
At the same time, two animals were anesthetized and the thoracic artery was observed.
As a result of observation, it was observed that the vasoconstriction of the administered dose of the composition prepared according to the example was rapidly suppressed as compared with the administered dose of the extract alone. It was confirmed that vexibinol and kurarinone of flavanone, an effective substance of gosam, were rapidly absorbed by the transport of sulfur.
Experiment 2.
In order to know the function of enhancing the effect of the active ingredient of the mountain sole composition containing MSM, the effect of the ginseng padoxanic acid composition containing the MSM prepared in Example 3 was tested.
Six individuals with no disease were separated into two groups of 3 persons with no disease. One group was used as a control group, and the composition prepared by using the traditional herbal ginseng paddoxan prescription was taken 6g each time for 3 times a day for 15 days. The composition prepared according to Example 3 was administered once a day for three times for 15 days, and the daily biorhythm and vitality were observed. As a result, the group that received the conventional ginseng peroxidase showed fatigue and respiratory disorder And in the group taking Ginseng Pedodoxane containing MSM, all three patients had less fatigue and respiratory disturbances in addition to more than one third of the normal exercise amount.
Experiment 3.
The composition containing Saururus 4, Saururus chinensis, and Mung bean is a substance used in health functional food by the function of detoxifying the poison in the body without the humid heat in the body, and the ginseng is added for the purpose of neutralizing the quality of Saururus chinensis .
Six rabbits were divided into two groups: the experimental group and the control group. Oral administration of 0.005 g of flukumapine to all six rabbits was followed by oral administration of 50 g of each of the compositions prepared in Example 4 to 3 rats, Were observed without administration. The mortality time of the three rats receiving the experimental composition was longer than that of the control group rats by about 3 hours. In addition, the findings of the dissection were observed in 3 rats fed with the experimental composition, the blood was not completely coagulated, and the rats in the control group observed that the blood was completely clotted.
MSM increased the efficacy of Sanjiao, and it was able to confirm that it has an admiral effect.
Experiment 4.
Effect of Garlic Extract, Egg Yolk Extract, and Sulfur (MSM) Lipid.
In order to measure the blood lipid-lowering effect of the mixed composition, blood was collected from an obese animal model mouse induced by high fat diet, and glucose, total cholesterol, triglyceride, low density lipoprotein (low-density lipoprotein, LDL) and high-density lipoprotein (HDL) were used as hematological indicators to measure their content in the blood.
After 5 weeks of high-fat diet and feeding of the composition prepared in Example 5, the blood collected from an experimental animal model mouse was left at room temperature for 30 minutes and centrifuged at 3,000 rpm for 15 minutes to obtain serum. The contents of glucose, total cholesterol, triglyceride, low density lipoprotein and high density lipoprotein were measured using the blood biochemical analyzer.
As a result, the concentration of total lipid, total cholesterol and triglyceride in the case of Example 5 was significantly lower than that in the high fat diet.
Experiment 5.
A mixture of garlic extract, I ghkd chutuli water, MSM, Sanjia extract, improve heart disease and cardiovascular disease and check the therapeutic effect.
One patient who underwent coronary artery stenting with coronary artery stenosis including hypertension was administered the food composition of Example 6 under the guidance of a physician for 3 weeks. During the administration, blood components of the physician were examined and blood pressure was measured.
After 3 weeks of administration, the MRA findings showed significant disappearance of intravascular lipid hardening.
Experiment 6.
Experimental study on the effects of the extracts of garlic, MSM, egg yolk extract and MSM on the growth of the artificial grasses on each composition including the artichoke.
6 patients with hypertension, 6 patients with myocardial ischemia of the heart, and 6 patients with arthritis pain were administered to 3 patients each of the compositions prepared in 7 above.
After 4 weeks of administration of the food composition, the physician's opinion showed that blood pressure was improved, myocardial weakness was improved, respiration was normalized, and joint pain was significantly improved. As a result of observing the improvement of the observation of patients taking only Sanayasochi, it was slightly improved but not improved remarkably.
Claims (4)
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| KR1020150126762A KR20170029764A (en) | 2015-09-08 | 2015-09-08 | Garlic extracts, egg yolk extracts and sulfur mixture to back out of the prevention of cardiovascular, cerebrovascular and other circulatory organ system disease, for the inclusion of active ingredients and treatment of functional foods, improvement and the manufacturing method. and Health functional food, organic sulphur (MSM)as active ingredients composition |
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| KR1020150126762A KR20170029764A (en) | 2015-09-08 | 2015-09-08 | Garlic extracts, egg yolk extracts and sulfur mixture to back out of the prevention of cardiovascular, cerebrovascular and other circulatory organ system disease, for the inclusion of active ingredients and treatment of functional foods, improvement and the manufacturing method. and Health functional food, organic sulphur (MSM)as active ingredients composition |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20200062452A (en) | 2018-11-26 | 2020-06-04 | 영월고소애협동조합 | Herbal medicine composition for promoting blood circulation, including Gosue |
| CN116392527A (en) * | 2023-03-10 | 2023-07-07 | 山东宏济堂制药集团股份有限公司 | A medicinal and edible product for improving chronic kidney disease |
-
2015
- 2015-09-08 KR KR1020150126762A patent/KR20170029764A/en unknown
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20200062452A (en) | 2018-11-26 | 2020-06-04 | 영월고소애협동조합 | Herbal medicine composition for promoting blood circulation, including Gosue |
| CN116392527A (en) * | 2023-03-10 | 2023-07-07 | 山东宏济堂制药集团股份有限公司 | A medicinal and edible product for improving chronic kidney disease |
| CN116392527B (en) * | 2023-03-10 | 2024-02-13 | 山东宏济堂制药集团股份有限公司 | Preparation for improving chronic kidney disease |
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