KR100948281B1 - The method of preparing the functional food for diet using extractive extracted from madicin-materials of plants - Google Patents

Abstract

PURPOSE: A method for manufacturing diet food using crud drugs is provided to improve antiobesity function by offering beneficial components while increasing recovery rates of active ingredients with crud drugs extract having blood pressure reduction and cholesterol reduction effects etc. CONSTITUTION: A method for manufacturing diet food using crud drugs includes the following steps: making a crude drug composition with 9.43wt% of the crude drug in a first group and 5.66wt% of the crude drug in a second group; manufacturing first extraction filtrate by filtering extract of the crude drug composition in a sealed container maintained with the temperature of 60~70°C; manufacturing second extraction filtrate by filtering and separating extract after evaporating alcohol in a temperature of 78~83°C; acquiring extracted concentrate; and manufacturing powder of the extracted concentrate by drying and freezing the extracted concentrate.

Description

TECHNICAL MANUFACTURING METHOD OF DIET FOODS WITH EXTRACT USING THE FARMED Medicinal Herbs {THE METHOD OF PREPARING THE FUNCTIONAL FOOD FOR DIET USING EXTRACTIVE EXTRACTED FROM MADICIN-MATERIALS OF PLANTS}

The present invention relates to a method for manufacturing a diet food using a plant herbal medicine, and in particular, a domestic registered patent of the applicant of the present application which is related to the problems of the conventional dietary herbal food or herbal diet food and the present application (registration number 10-0891914). Fennel (Fennel or Foeniculum) having the main function of anti-obesity by reviewing trial and error that occurred during the commercialization process and research result report (study on anti-obesity health efficacy of plant herbal composition containing fennel) Fractus) The first group of plant herb extracts that contain synergistic effects and add synergistic effects to fennel, and supplements with blood pressure drop, cholesterol reduction, and smooth metabolism that must be accompanied by such anti-obesity effects. It becomes a mixed extract of the second group of plant herbal extracts that perform the functional function or lyophilizes the mixed extract. To a method of producing food for dieting by the herbal plants as a powder.

Referring to the outline and necessity of the present invention development technology,

Increasing intake of simple sugars, meat, fats, etc., which are changes in the diet patterns of modern people, has increased the prevalence of various chronic human diseases, and these diseases are closely related to obesity. In order to prevent and treat adult diseases, which have recently become socially and economically serious, scientific research and development that can improve or cure obesity is urgently needed.

Obesity in humans includes excessive calorie intake, endocrine disorders, lack of exercise, and genetic factors. However, the main mechanism of development is an imbalance between energy intake and consumption. When energy consumption efficiency is poor, obesity occurs due to fat accumulation. Simplicity (essential) obesity and endocrine diseases (insulin-dependent diabetes mellitus, cushing syndrome, ovarian insufficiency, hypothyroidism) or hypothalamic disorders (which appear when the brain's bloat is central). Symptomatic obesity due to some causes obesity, 95% of obesity is a simple obesity.

In addition, obesity is known to cause abnormal physiological function due to excessive accumulation of fat in the body and cause various chronic diseases such as diabetes, cardiovascular disease, lipid metabolism abnormality, and cancer.

Currently developed and commercially available obesity treatments include appetite suppressants that stimulate the hypothalamus to suppress appetite, sibutramine, phentermine, dibutylpropion, phendimetrazine, and benzpetta There are benzphetamine and methamphetamin, orlistat, which inhibits the absorption of fat ingested using pancreatic lipase inhibitors, and alpha-glucosidase inhibitor. Although acarbose is used as an anti-obesity agent, the medicinal obesity drug developed so far shows excellent efficacy but insomnia, nervousness, headache, tachycardia, increased blood pressure, gastrointestinal disorders, irritability, bile secretion disorders, and fat-soluble vitamin absorption suppression. It is known to be accompanied by serious side effects.

Despite many research and development, the development of anti-obesity functional foods or products using natural products without side effects has recently been greatly attracted since no medical treatments or drugs have been developed.

In order to improve obesity, a simple bio-marker is proposed as a study on obesity, because a fundamental curative or improvement cannot be achieved by simply suppressing appetite function and inhibiting absorption of fat ingested using pancreatic lipase inhibitor. have.

So far, the results of the present application for the verification of anti-obesity efficacy,

First, material extraction is needed to improve the lipid content in the blood, which means that the higher the weight, the higher the lipid concentration in the blood. In particular, the total cholesterol and triglyceride rise in the blood have a high correlation with obesity. Therefore, the effect of lowering the content of triglyceride and total cholesterol in the blood in the animal experiments that induced obesity in a high fat diet can be said to have anti-obesity effect.

Second, material extraction is needed to improve the number and size of fat cells, weight gain and abdominal visceral fat are positively correlated, and fat cell size is significantly correlated with body fat mass. Therefore, the change in the number and size of adipocytes is an essential indicator to verify the anti-obesity effect.

Third, material extraction is needed to improve the activity of intracellular lipid metabolism-related enzymes, and lipids transferred to cells are used in one of two pathways: synthetic metabolism and degradation metabolism. Increased activity of enzymes related to promote energy consumption and increase energy activity of enzymes involved in synthetic metabolism to induce energy accumulation.

The present invention is an invention attempted in the above-mentioned direction of technical development, but looking at specific embodiments of the related art related to the present invention,

Domestic Patent Publication (Registration No. 10-0597036) "Diet nutrition composition is introduced and the technical content of soybean protein, milk protein, dietary fiber, oligosaccharides, nutritional composition of hawthorn, cassia, persimmon leaf and menstrual extract, collagen It relates to a diet nutrition composition, and as another conventional technology, a domestic diet patent (Registration No. 10-0856241) is introduced "a diet food composition using agar," the contents of the technology, namely agar, carcinia gambosia, Indigestible maltodextrin, various grains, lactic acid bacteria, green tea, L-carnitine, Baeknyeongryeong, Astragalus, Eoseongcho, Soybean powder, Soychocho, Chicory, Vegetables, Kelp, Soybean, Pumpkin As another conventional technology, "reproductive and gland composition" is introduced as a method of reducing or eliminating obesity in Korea Patent Publication (Publication No. 10-2003-83347). Korean Patent Publication (Publication No. 10-1998-8055) also introduces diet compositions composed of a group of cereals, a group of vegetables, a group of mushrooms, and a group of herbs as a "health diet."

The above-mentioned prior arts are diet foods or compositions consisting of nutritional substances, herbal medicines, and functional substances. Even though there is a great difference in the properties and conditions of each component, even the basic method of blending or composition is not described. Not only does not contain any ingredients for each of the components constituting the diet foods or compositions that consist of simply listing or combining each component, so that more than the function or effect of each component can not expect a diet food It may be referred to as a composition.

In addition, this is a research result on the anti-obesity health efficacy test of food and drug composition containing fennel, which is a Korean registered patent (Registration No. 10-891914) which is related to patent application. According to the results of the study, an improved and complementary invention first needs to minimize the loss of active ingredients in the extraction of herbal medicines, and at the same time, supplement the methods or means for the smoothing of the auxiliary functions in parallel with the anti-obesity function.

The present invention provides a method for producing a diet food using a plant herbal medicine and by removing various factors causing the loss of the active ingredient in the extraction of various active ingredients from the plant herbal medicine to increase the recovery rate of the active ingredient to the maximum and at the same time excellent Elevated anti-obesity function by activating each organ of the human body at the same time by performing the balanced function of plant herbal medicine extract of the first group including fennel with obesity (diet) function, lowering blood pressure, lowering cholesterol and smooth metabolism It is to provide a method for producing a diet food using a plant herb extract of the second group of plant herb extracts to have an effect.

The first group to increase the anti-obesity function by adding to the fennel (Fennel, Foeniculum Fractus) component having an anti-obesity (diet) main function based on the results of the above experiment in selecting a plant herbal medicine for the production of diet food It is added to the food herbal medicine and fennel and the first group of food herbal medicine to balance the secondary functions such as lowering blood pressure, reducing cholesterol, and smooth metabolism, and by activating various organs of the human body at the same time, indirect synergistic effect on the anti-obesity function In selecting and extracting two groups of plant herbs to give them, fennel 84.91wt% and at least one plant herbicide selected from the group 1 plant herbs 9.43wt%, at least one plant herbicide selected from the group 2 plant herbs 5.66wt The total herbal composition composed of% was filtered by compressing or centrifuging the extract extracted with primary distilled water. The secondary filtrate was obtained by adding the first aqueous filtrate and extracting by adding the aqueous alcohol solution to the compressed and centrifuged residue and the filtered residue to increase the recovery rate of the active ingredient contained in the plant herbal medicine by mixing the primary and secondary extracts. The object of the present invention can be achieved by adding a natural sugar solution to the concentrated extract solution with concentrated mixed extract or by forming a freeze-dried powder of the concentrated extract with a natural binder to provide a food formulation for spherical shape and annular shape.

Functional food for diet with plant herbal extract according to the present invention has a high content of active ingredients while minimizing the loss of active ingredients contained in plant herbal medicines, and among enzymes related to lipid metabolism by fennel and the first group of plant herbal extract concentrates. By inhibiting the activity of LPL, the body fat of triglyceride in blood can be used as an energy source, and it can have an excellent anti-obesity effect by improving and preventing obesity. The anti-obesity action of a group of herbal medicines of the group together with supplementary functions to balance the activation of each organ of the human body at the same time can be called a diet food using a herbal medicine that has a synergistic effect of anti-obesity function.

Plant herb used in the diet food of the present invention is 84.91% by weight of fennel having the main function of anti-obesity (diet) and fennel and complexes to increase the anti-obesity function of cloves, casualties, whitening or creation, Astragalus, chacha, deficiency, 9.43% by weight of one or more first-class plant herbal medicines selected from Bokryeong, a plant herbal medicine that has an indirect synergistic effect on anti-obesity by an auxiliary function of activating each organ of the human body as red ginseng, Eui-in, Shiho, Taeksa Maintained at a temperature of 60-70 ° C. with distilled water corresponding to 10 times the weight of the whole plant herbal composition consisting of 5.66% by weight of at least one second group of plant herbicides selected from among aging, red bean curd, windproof, organza, wolfberry, and dermis Extracted from the sealed container for 24 hours, compressed filtration or centrifugal filtration to obtain the primary filtrate, 60 times the weight of the crude drug residue produced in the previous process 60 After immersing in the aqueous alcoholic solution of% and maintaining the temperature at 78 ~ 83 ℃ for 5 hours, the majority of the alcohol (ethanol) was evaporated and the extract was compressed and filtered to obtain a secondary filtrate. It may be referred to as a diet food using a plant herbal medicine by adding natural sugar to the extract concentrate concentrated under reduced pressure by mixing.

In addition, the present invention is a diet foods made of plant herbal extracts spherically shaped and annular by adding one of honey, natural sugars and alginate as a natural binder to the powder of the plant extracts prepared by the lyophilization method. It is included, the amount of natural binder is 5 ~ 10wt% is suitable.

In the above method, the extraction temperature with distilled water or the extraction with alcoholic solution is advantageously extracted at the lowest possible temperature. When processed at a temperature higher than 100 ℃ with pressure, especially plant-derived substances such as fennel and cloves, as well as other plant herbals, decomposition or loss of botanical components with low boiling point or low decomposition temperature may occur. The herbal medicine contains various ingredients, and among the various ingredients, both the water soluble component and the organic solvent (alcohol) component are contained together. Plant herbal medicines are obtained by distilling the ingredients into groups and extracting only with water or solvents (ethanol) to obtain a mixed extract. It is 8 ~ 1 in terms of extraction efficiency of the active ingredient to obtain a mixed extract mixture of secondary extracts. It can be increased by 2%.

And in the case of extracting heat treatment by adding alcohol aqueous solution to the plant herbal extract residue, the alcohol (ethanol) used here is recovered and controlled to be used for the extraction of the next plant herbal residue, and the concentrated concentration of the extract is 200-300 Torr. It is carried out under the reduced pressure in the range of 40 ~ 50 ℃, and the extractable concentrate can obtain 8w% of the input of the herbal medicine and 0.5wt based on the total total treatment input of the plant herbal medicine, water and alcoholic aqueous solution. You can get%. In addition, in the case of powder drying by freeze drying with the extract concentrate, the extract concentrate is sprayed onto a metal or plastic plate and dispersed and coated to form a thickness of 1 to 2 mm, and then freeze-dried at a range of -60 to -70 ° C. It can be obtained and pulverized and sealed with moisture content of 5wt% or less. When the powder is obtained by freeze-drying, a powder of 2 wt% of the input weight of the herbal medicine can be obtained, and a powder of 0.125 wt% of 5 wt% of water content can be obtained with respect to the total treatment dose. In other words, if you extract 1000 kg of plant herbs, you can get 80 kg of extract concentrate and 20 kg of powder.

If we look at the components and functional functions of the herbal medicines used in the diet food manufacturing method, the first group of herbal medicines consisting of fennel, clove, casualties, baekrye, Astragalus, chajeon, gyeongmyeong, Bokryong are registered in Korea. It is described in detail in the patent publication (Registration No. 10-891914), and describes the second group of plant herbal medicines which is a group of red ginseng opiate, shiho, taxa, geranium, red bean curd, windproof, ogapi, wolfberry, and dermis. ,

Red ginseng is dried red ginseng and is called red ginseng. Like ginseng, glycosides, ginseng fragrances (panacen), polyacetylene-based compounds, nitrogen-containing compounds, polaroids, vitamins (group B), trace elements, enzymes, antioxidants, organic acids and Contains amino acids,

The central nervous system has sedation and excitement effects on the circulatory system, which has the effect of preventing hypertension or arteriosclerosis. It also lowers hematopoietic and blood sugar levels, protects the liver, and acts indirectly on sexual and reproductive effects by acting on the endocrine system, has anti-inflammatory and anti-tumor effects, protects against radiation, and protects the skin. It also works to soften.

Red ginseng has been scientifically proven to have the ability to adapt more easily to the body by increasing the ability to protect against various diseases such as eye disease, stress, etc., which are important effects of the adaptogen (adaptogen) effect from the environment.

Shiho is also known as celery and green sprouts. Its components include saponins, flavonoids, coumarins, tannins, sesquiy terpenlactone, and its actions include heat-lowering, edema, sterols, and α-spinasterol. Decreases plasma cholesterol content.

Taxa is also called talc, perennial herb, perennial, with essential oils, resins, acetylcholine, lecidin, asparagine, high amounts of amino acids, sugars, pitsterol, pitsterol, oils (palmitin, stearin, olein), It contains alkaloids, plenty of horses (23%) and protein (7%). Recently, alisole, a monoacetar, and epi-alisol A, which are tetracyclic terpenoids, have been obtained from Taxa.

Root stem is a pissing effect in animal experiments and lowers the concentration of urea and cholesterol in the blood. In clinical trials, there was a urinating effect, and urine was found to increase the excretion of urea and chloride and lower sugar content. In addition, it is effective in treating fatty liver caused by feeding protein mixed with cholesterol in animal experiments, and has a function to heal wounds of blood vessel walls caused by cholesterol deposition. These actives are believed to be due to choline, lecithin, and alisol.

It is called oak root or mushroom, and it is also called gnome, sperm and feng shui. The mycelium is formed in the shallow ground where the leaves are piled up, and its shape is similar to ginger, and it is a lump of oak, maple, birch and birch. , Occurs on the dead roots of pine trees. The action is to increase the amount of urine, and urinary action appears because it suppresses the reabsorption of water and electrolyte in the kidneys. Injections into dogs increase urine output and increase excretion of sodium, kalium and chromium ions. In motion therapy, it has been used as urine medicine, kidney disease, and fever medicine.

Red beans are red beans, which contain 2% water, 0.75% oil, 0.7% fatty acid alkali salts, and 0.27% saponin protein (pazeolin).

Fatty acids are palmitic acid, stearic acid and alaginic acid, and when saponin is broken down into water, it becomes sapongenin, glucose, arabinor and rhamnose. Nitrogen compounds include adenine, trigonelin hydrochloride, choline, and allantoin in small amounts of creatine and vitamins B ₁ , B ₂ , and PP. In motion therapy, urine drugs have been used for kidney, jaundice, and the like.

Windproof is a perennial herb that is dried in the casserole in the fall. Root contains 0.23--0.88% coumarin essential oil. Etulin is one of the coumarin ingredients, and it has been used as an antipyretic medicine for wind, head pain and antiperspirant medicine.

Ogapi is also called hwahwa, wooden bone. Ogapi bark is called Ogapi. Ogapi contains glycoside acantosheet, tannins about 7%, essential oils, vitamins A and C. It contains salicialdehyde and the oil is a glyceride of palmitic acid and arachnic linoleic acid. The glycoside component is not yet known in composition, but it is composed of lignin nucleogen and various sugars.

It works by recovering mental and physical fatigue and has adaptive activity. It is used as a hyperlipidemic humectant.

Goji berries are the fruit of the Goji berry tree and contain 0.1% vitamin and zeaxanthin, a carotenoid. In recent years, the first biologically active substances, scoplatin, capotenoid and sterin, have also been isolated from goji berry, which is pisalien and β-stosterin.

The leaves contain betaine, doucosterin, ascorbic acid, and also ash, Si, K, Na, Ca, Ma, Fe, P, S, Zn, F, etc.

Gojija has a function of lowering blood pressure, and betaine is a lipid affinity as one of the metabolites of choline. Betaine hydrochloride acts as a methyl-based feedstock for choline metabolism.

It also reduces the amount of blood cholesterol, so it is used to prevent and treat arteriosclerosis.

The dermis is the fruit peel of the tangerine tree, and the fruit contains 1 ~ 3% of organic acid mainly composed of lemon acid, asparagine, proline, r-aminobutyric acid, and the fruit peel contains essential oil and hesperidin. Hesperidin is hydrolyzed to hesperetane, glucose and rhamnose.

Actions include aroma odor, and heperidine and other flanoid components have vitamin P activity and have an idiot effect.

The object is dried seeds of Yulmu, which contains 8-20% protein, 2-8% fat, 50-78% carbohydrate and 0.5-2.3% ash. The amino acids that hydrolyzed the protein were 21% leuchin, 2% tyrosine, 0.5% alanine, 1.2% phenylalanine, 15% glutamic acid, 17% arginine, 2% tropin, 0.2% aspirazine, 0.15% histidine, and tryptophan. (Oil) is a glyceride of palmitic acid, stearic acid, myristic acid, cis-8-octademic acid (coicic acid), and the unsaponified portion includes β-sitosterol, some α-citsterol, camphorsterol, and stigmasterol .

Most carbohydrates are farm horses, and ash contains P, Mg, Mn, Ca, Fe, Al, Zn, Ba, Cu, Mo, Sn, Ni and the like.

Seed contains acetonitrile C ₃₈ H ₇₀ O ₄ in the acetone extract. This material is a single molecule of cis-9-hexademic acid and trans-11-octademic acid. Seeds also contain about 150 mg choline (free or combined) and organic acids. 35% of the organic acids are butteric acid, 60% of oxypropionic acid and some other organic acids.

Roots contain stearic and palmitic glyceride oils, β-sitosterol, r-sitosterol, α-sitosterol, stigmasterol, essential oils 0.1%, Coixsol (C ₈ H ₇ O ₃ N, 6-methoxybenzoxazolone, greening Point 151-152 degreeC).

In terms of action, the protein content of seeds is higher than rice and wheat, which are plants and rice, and there are many essential amino acids, including leucine. In addition, there are other ingredients that are good for human nutrition, including oils and trace elements.

Seed also has anti-inflammatory, lowering hypercholesterolemia. Coixenolide has a proliferation inhibitory effect on Erlich's multiple cancer. In addition, the pharmacological action of seeds has been examined a lot, but researchers have different opinions.

Coixol obtained from the root has pain and sedative action, the strength of the action corresponds to 100mg / kg of Coixol 145mg% aminophylline. Coixol also reduces blood sugar levels.

These actions were obtained in acute trials and were rarely examined in chronic and clinical trials.

Mr. has been writing for a long time. In motion therapy, it is used for swelling, swelling diseases, neuralgia, and joint pain with inflammatory medicine, urine medicine, pear pesticide, and pain medicine. It is also used to remove warts.

Roots are used as insect repellent in the private sector and used for nerve pain and arthritis.

Coixol can also be injected into nerve pain. It is said that if you make rice or rice cake with Yulmu rice and eat it for a long time, you will be healthy.

Yulmu's Decoction (10 ~ 30: 200) -Dining three times a day. Used to treat infectious warts or bumps (molluscum contagiosiosum).

A study on the study on anti-obesity health efficacy test of plant herbal composition containing Fennel (Fennel, Foeniculum Fractus) for the practice of the present invention (Fennel and according to the results of Kangwon National University Well-being special product industrial innovation center) When the extract of the fennel mixture was added, the anti-obesity effect was evaluated in Example (1) by measuring the activity change of enzymes related to inhibition of fat accumulation in cells and the activity change of enzymes related to the promotion of lipolysis use.

Example (1)

Specifically, a group consisting of one or more herbal medicines selected from one group of herbal medicines consisting of casualty, cloves, white extract or creation, Astragalus, chacha, lame, and Bokryong to 90 parts of fennel alone The plant extract was 10 parts by weight (case 5: clove 3: white extract 2) according to the above-described method to the primary extraction and secondary extraction to obtain a mixed extract and was tested with the concentrated extract concentrate.

1. Anti-obesity test results.

1) In vitro experiment.

The results of the comparison with the control group without the addition of the fennel or fennel-containing extracts were as follows.

(1) Changes in the activity of key enzymes related to lipid metabolism.

 Activity of Lipoprotein lipase (LPL) Enzyme Normal cells Add Fennel 21.9% Suppression Add Fennel Mixture 25.3% Suppression In case of mast cells Add Fennel 12.0% Suppression Add Fennel Mixture 14.8% inhibition Activity of Acyl-CoA synthetase (ACS) Enzyme Normal cells Add Fennel 151.8% increase Add Fennel Mixture 152.9% increase In case of mast cells Add Fennel 842.0% increase Add Fennel Mixture 401.7% increase Activity of Carnitin acetyl trasnferase (CAT) Enzyme In case of mast cells Add Fennel 103.5% increase Add Fennel Mixture 131.2% increase Activity of Hormone Sensitive Lipase (HSL) Enzyme Normal cells Add Fennel 174.0% increase Add Fennel Mixture 136.0% increase In case of mast cells Add Fennel 134.0% increase Add Fennel Mixture 111.0% increase

2) In vivo (animal experiment)

The results of comparing the high-fat diet Fennel intake group with the high-fat diet only control group were as follows. I made it.)

(1) Body weight and epididymal fat, liver tissue weight.

Body weight gain / food intake Liver tissue (g / mouse) Epididymal Fat (g / mouse) 26.56% decrease 22.56% decrease 29.19% decrease

(2) plasma lipid and glucose content.

Total-cholesterol HDL-cholesterol LDL-cholesterol Triglyceride Glucose 5.27% decrease 2.09% decrease 5.83% decrease 20.89% decrease 16.58% decrease

(3) epididymal adipocyte size.

21.41% reduction compared to the control group fed only high-fat diet.

(4) Changes in key enzyme activity of lipid metabolism.

Lipoprotein lipase Acyl-CoA synthetase 33.41% activity inhibition 330.99% increase in activity

To summarize the results of the experiment,

* In vitro experiments showed that the addition of fennel extract or fennel extract (Fennel 90, casualty 5, cloves 3, and 2 parts by weight) inhibited the activity of Lipoprotein lipase (LPL), resulting in intracellular triglyceride Reduces inflow and regulates HSL to promote the breakdown of stored fats in adipose tissue to reduce body fat and activate enzymes of ACS to promote catabolic pathway of imported fatty acids to use fatty acids as energy sources to improve obesity and prevent In addition, it did not significantly affect the activity of CAT enzyme, but it was judged to have anti-obesity effect by other enzyme activity or other experimental mechanisms.

* In vivo test results showed that high-fat diet increased the weight of body weight, liver tissue and epididymal fat, and water extract of fennel inhibited or decomposed fat accumulation in liver tissue, which was effective in improving obesity. Fennel extract is thought to reduce the accumulation of triglycerides and reduce the risk of cardiovascular diseases caused by obesity.

As shown in the in vivo (animal experiment) in the experimental results of Example (1), most of the items can be expected to have an excellent anti-obesity effect, but the effect of reducing the plasma lipid content is low, and thus the blood pressure lowering effect in the blood pressure measurement of the mice The results were not significant, and urine or faeces and feces were not much higher than the control group.

In order to supplement the above problems, the components and functional functions of the herbal medicines are extracted from the literature, and these are composed of red ginseng, uiin, shiho, taeksa, ghost, red bean curd, windproof, organza, goji berry, and dermis through numerous experiments. A second group of plant herbs was selected.

Example (2)

5.66 wt% of the plant herbal compositions of Example (1) (84.91 wt% fennel at least one plant herbicide selected from the first group of plant herbicides) and at least one plant herbicide selected from the second group of plant herbicides. % (Here red ginseng 2.83wt%, Ogapi 1.89wt%, wolfberry 0.94wt%) was added to obtain an extract concentrate according to the method described above.

Plasma lipid and glucose content of the extract concentrate was tested according to the anti-obesity efficacy test described above.

Table (1) Plasma lipid and glucose content.

Item ＼ Classification Extraction Concentrate of Example (1) Addition of Extract Concentrate of Example (2) Total-cholesterol 5.27% decrease 9.45% decrease HDL-cholesterol 2.09% decrease 4.2% reduction LDI-cholesterol 5.83% decrease 9.91% decrease Triglyceride 20.89% decrease 23.72% decrease Glucose 16.58% decrease 18.84% decrease

As shown in the above Table (1), compared with the loss of the form lipid and glycerides and glucose shown in the experimental results of the extraction concentrate of Example (1), the extraction result of the experiment was performed by adding the extract concentrate of Example (2) As a result of significantly reducing plasma lipids, glycerides and glucose content as compared with the control group ingesting only the dietary formula, blood pressure of the experimental mice was significantly reduced in the experimental results, and the extract concentrate of Example (2) was used. In case of testing other items except the items in Table (1) shown in the experimental results of (1), there was no significant difference in selecting any of the plant herbicides of the second group in the range of 6wt%. By adding the plant herbal medicine of the group to the plant herbal composition of Example (1) it can be said to the embodiment of the present invention to compensate for the lack of the embodiment (1).

As shown in Example (1), the concentrated plant extracts of the first group, including fennel, inhibited the activity of LPG in enzymes related to lipid metabolism, lowered the intracellular influx of triglyceride in the blood, and regulated HSL. Reduce body fat and activate enzymes of ACS to use fatty acids as energy sources for anti-obesity effects of improving obesity and preventing obesity, and the second group of plants added to the first group of herbal medicines including fennel Herbal medicines, such as the function or action caused by the components of the second group of plant herbal medicines, such as the urinary action (peeing action), smooth excretion metabolism action, such as diarrhea effect, reducing plasma cholesterol content, cholesterol reduction It is a function and action of lowering blood pressure according to the anti-obesity action of the first group of herbal medicines including fennel and ancillary functions Can be active at the same time as the row hameuroseo because every organ of the body, wherein the food for the stand as a herbal plant extracts that have a synergistic effect of obesity functionality diet.

Claims (4)

Fennel 84.91wt%, casualty, cloves, extract or creation, Astragalus, chaser, defector, Bokryeong, at least one group of herbal medicines of the first group 9.43wt%, red ginseng, objection, shiho, taxa, spirits, red beans, windproof One-step process of forming a plant herbal composition with 5.66 wt% of at least one second group of herbal medicines selected from among organs, organza, wolfberry, and dermis, The second step of obtaining the first extraction filtrate by separating the extract obtained by distilled water corresponding to 10 times the weight of the plant herbal composition in an airtight container maintained at a temperature of 60 ~ 70 ℃ 24 hours into an extract and a residue and filtering the extract fair, After immersing the plant herbal medicine residue in the second step in 60% alcohol solution corresponding to 5 times the weight, the temperature was maintained at 78 ~ 83 ℃ and extracted for 5 hours to evaporate the alcohol, and then the extract was separated and filtered. Three step process of obtaining filtrate, The mixed filtrate mixed with the primary filtrate and the secondary filtrate was kept at a pressure of 200 to 300 Torr at a temperature of 40 to 50 ° C. to obtain an extract concentrate concentrated until 8 wt% of the total amount of the herbal medicine was added. Method for producing a diet food using a herbal medicine consisting of a step process. A method for producing a dietary food using a plant herbal medicine further comprising the step of lyophilizing the extract concentrate obtained in the step 4 of claim 1 to prepare a powder of the plant herbal extract concentrate. delete The method of claim 2, wherein the powder of the extract concentrate is 2 wt% based on the total amount of the plant herbal medicines.