CN106234367A - A kind of containing fluopicolide and the bactericidal composition of methoxy acrylic - Google Patents
A kind of containing fluopicolide and the bactericidal composition of methoxy acrylic Download PDFInfo
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- CN106234367A CN106234367A CN201610653482.XA CN201610653482A CN106234367A CN 106234367 A CN106234367 A CN 106234367A CN 201610653482 A CN201610653482 A CN 201610653482A CN 106234367 A CN106234367 A CN 106234367A
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
- A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/44—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
- A01N37/50—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids the nitrogen atom being doubly bound to the carbon skeleton
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Abstract
The invention discloses the bactericidal composition of a kind of containing fluopicolide and methoxy acrylic, bactericidal composition containing active components A Yu active component B, active components A is selected from fluopicolide, active component B is selected from any one compound following: trifloxystrobin, fluoxastrobin, Enestroburin, ZEN 90160, kresoxim-methyl, and the weight ratio of active components A and active component B is 1: 80～60: 1.The present composition has greater activity to the multiple diseases in various crop, and has obvious potentiation, expands fungicidal spectrum.And have that dosage is little, resistance of rainwater washing against, the obvious feature of potentiation.
Description
The application is divisional application, and original application is patent application " a kind of fluorine-containing pyrrole bacterium of Shaanxi Meibang Pesticide Co., Ltd.
The bactericidal composition of amine and methoxy acrylic ", the Application No. 201210194378.0 of original application, original application day is
2012.6.13。
Technical field
The invention belongs to technical field of pesticide, relate to the Bactericidal composite of a kind of containing fluopicolide and methoxy acrylic
Thing application in crop pest.
Technical background
The chloro-N-[(3-of fluopicolide (fluopicolide) chemical name: 2,6-bis-chloro-5-trifluoromethyl-2-pyridine radicals)
Methyl] Benzoylamide, molecular formula: C14H8Cl3F3N2O.Fluopicolide is amide-type wide-spectrum bactericide, to Oomycete fungal pathogenic bacteria
There is the highest biological activity, there is protection and therapeutical effect.Fluopicolide has stronger permeability.Can be downward from blade upper surface
Face is permeated, and conducts to blade tip direction from phyllopodium.Blade can be protected not by infection process after plumelet is processed.Can also be from root edge
Plant xylem is distributed to whole strain crop, but can not conduct along phloem.
Methoxy acrylic is that the class developed for lead compound with natural methoxy acrylate antibiotic is new
Type antibacterial, is the mitochondrial respiratory inhibitor of pathogenic fungi, i.e. by electron transfer consistent line grain between cytochrome b with c1
The breathing of body, interference cell energy supplies, makes cell death, thus play bactericidal action.
In the real process of agricultural production, controlling disease is easiest to generate the problem that the generation of disease drug resistance.No
Compound with kind composition, be to prevent and treat the method that resistance disease is the most common.Heterogeneity compounds, according to reality application effect
Really, judge certain compounding be potentiation, add and or antagonism.In most cases, the compounding effect of pesticide all adds
And effect, really have potentiation compounding seldom, especially potentiation clearly, potentiation ratio the highest compounding the most more
Few.Study through inventor, find fluopicolide and trifloxystrobin, fluoxastrobin, Enestroburin, ZEN 90160, benzene oxygen bacterium
Ester is the most compounding, has good potentiation within the specific limits, and about fluopicolide and trifloxystrobin, fluoxastrobin, alkene oxime
Bacterium ester, ZEN 90160, kresoxim-methyl are relevant compounding, the most at home and abroad there is not yet relevant report.
Summary of the invention
The purpose of the present invention is to propose to a kind of there is synergistic function, use cost is low, preventive effect is good containing fluopicolide
Bactericidal composition with methoxy acrylic.
The present invention is to be achieved through the following technical solutions:
A kind of containing fluopicolide and the bactericidal composition of methoxy acrylic, containing active components A and active component
B, active components A and active component B weight ratio are 1: 80～60: 1, and described active components A is selected from fluopicolide, active component
B one in trifloxystrobin, fluoxastrobin, Enestroburin, ZEN 90160, kresoxim-methyl；Active components A and active component B
Preferred weight ratio be 1 60～40 1；More preferably fluopicolide is 1: 20～10: 1 with the weight ratio of trifloxystrobin, fluorine pyrrole bacterium
Amine is 1: 20～10: 1 with the weight ratio of fluoxastrobin, and fluopicolide is 1: 20～10: 1 with the weight ratio of Enestroburin, fluorine pyrrole
Bacterium amine is 1: 30～10: 1 with the weight ratio of ZEN 90160, and fluopicolide is 1 20～10 1 with the weight ratio of kresoxim-methyl；?
The weight ratio being preferably fluopicolide and trifloxystrobin is 1: 10～5: 1, and fluopicolide is 1: 10～5 with the weight ratio of fluoxastrobin
: 1, fluopicolide is 1: 10～5: 1 with the weight ratio of Enestroburin, and fluopicolide is 1: 15～5 with the weight ratio of ZEN 90160:
1, fluopicolide is 1 10～5 1 with the weight ratio of kresoxim-methyl.
The bactericidal composition of described containing fluopicolide and methoxy acrylic, compositions make wettable powder,
Water dispersible granules, suspending agent, aqueous emulsion, microemulsion, suspension emulsion, microcapsule suspending agent, microcapsule suspension-suspendinagent agent.
Described containing fluopicolide is used for preventing and treating the disease of crop with the bactericidal composition of methoxy acrylic, described
Crop include cereal crops, legume crop, fibre crops, sugar crop, melon crop, fruits crop, dry fruit crop,
Hobby crop, root crop, oil crop, flower crop, medicinal crop, crop, green manure pasture crop.
Described disease includes downy mildew, peronospora tabacina, early blight, late blight, gray mold, powdery mildew, rice blast, rust
Disease, white rot, scab, glume blight, net blotch, leaf blight, brown spot, moire disease, anthrax, spot defoliation, damping off.
In the bactericidal composition of the present invention, the content of active component depends on amount of application when being used alone, and also depends on one
Plant compound and the mixed ratio of another kind of compound and potentiation degree, also the most relevant with target disease.Generally group
In compound, the weight percentage of active component is the 1%～90% of gross weight, is preferably 5%～80%.According to different
Preparation type, active component content scope is different.Generally, liquid preparation contains the active matter of by weight 1%～60%
Matter, preferably 5%～50%；Solid preparation contains the active substance of by weight 5%～80%, preferably 10%～
80%.
At least containing a kind of surfactant in the bactericidal composition of the present invention, when being beneficial to use, active component is in water
Dispersion.Surface-active contents is the 2%～30% of total formulation weight amount, and surplus is solid or liquid diluent.
Surfactant selected by the bactericidal composition of the present invention is known in those skilled in the art: can be selected from
One or more in dispersant, wetting agent, thickening agent or defoamer.According to different dosage form, preparation can also contain this area
Stabilizer well known to technical staff, antifreeze etc..
The bactericidal composition of invention through dilution or directly can be used before use by user.Its preparation can be by this area
Prepared by the processing method well known to technical staff, will add table after active component mixes with liquid flux or solid carrier
One or more in face activating agent such as dispersant, stabilizer, wetting agent, binding agent, defoamer etc..
Compositions comprises following component and content when making wettable powder: active components A 0.5%～60%, activity become
Divide B 0.5%～80%, dispersant 1%～12%, wetting agent 1%～8%, filler surplus.
Compositions includes following component and content when making water dispersible granules: active components A 0.5%～60%, activity become
Point B 0.5%～80%, dispersant 1%～12%, wetting agent 1%～8%, disintegrating agent 1%～10%, binding agent 0～8%,
Filler surplus.
Compositions includes following component and content when making suspending agent: active components A 0.5%～50%, active component B
0.5%～50%, dispersant 1%～10%, wetting agent 1%～10%, defoamer 0.01%～2%, thickening agent 0～2%, anti-
Freeze agent 0～8%, deionized water add to 100%.
Compositions includes following component and content when making aqueous emulsion: active components A 0.5%～50%, active component B
0.5%～50%, solvent 1%～20%, emulsifying agent 1%～12%, antifreeze 0～8%, defoamer 0.01%～2%, thickening
Agent 0～2%, deionized water add to 100%.
Compositions includes following component and content when making microemulsion: active components A 0.5%～50%, active component B
0.5%～50%, emulsifying agent 3%～25%, solvent 1%～10%, antifreeze 0～8%, defoamer 0.01%～2%, go from
Sub-water adds to 100%.
Compositions includes following component and content when making suspension emulsion: active components A 0.5%～50%, active component B
0.5%～50%, emulsifying agent 1%～10%, dispersant 1%～10%, solvent 1%～20%, defoamer 0.01%～2%,
Thickening agent 0～2%, antifreeze 0～8%, deionized water add to 100%.
Compositions includes following component and content when making microcapsule suspending agent: active components A 0.5%～50%, activity become
Divide B 0.5%～50%, macromolecule cyst material 1%～10%, dispersant 2%～10%, solvent 1%～10%, emulsifying agent
1%～7%, pH adjusting agent 0.01%～5%, defoamer 0.01%～2%, deionized water add to 100%.
Compositions includes following component and content when making microcapsule suspension-suspendinagent agent: active components A 0.5%～50%, live
Property composition B 0.5%～50%, macromolecule cyst material 1%～12%, dispersant 1%～12%, wetting agent 1%～8%, molten
Agent 1%～15%, emulsifying agent 1%～8%, defoamer 0.01%～2%, thickening agent 0～2%, pH adjusting agent 0.01%～
5%, deionized water adds to 100%.
The wettable powder the key technical indexes of the present invention:
The water dispersible granules the key technical indexes of the present invention:
The suspending agent the key technical indexes of the present invention:
The aqueous emulsion the key technical indexes of the present invention:
The microemulsion the key technical indexes of the present invention:
The suspension emulsion the key technical indexes of the present invention:
The microcapsule suspending agent the key technical indexes of the present invention:
The microcapsule suspension-suspendinagent agent the key technical indexes of the present invention:
It is an advantage of the current invention that:
(1) present composition has good potentiation and lasting effect within the specific limits, and preventive effect is higher than single dose；(2) agriculture
Medicinal dose reduces, and reduces pesticide residual quantity on crop, alleviates environmental pollution；(3) fungicidal spectrum is expanded, to multiple diseases
As downy mildew, peronospora tabacina, early blight, late blight, gray mold, powdery mildew, rice blast, rust, white rot, scab, grain husk withered
Disease, net blotch, leaf blight, brown spot, moire disease, anthrax, spot defoliation, damping off have greater activity.
Detailed description of the invention
Below in conjunction with embodiment, further instruction of the present invention, the percentage ratio in embodiment are all weight percentage, but
The invention is not limited in this.
Application Example one
Embodiment 1～12 wettable powder
By fluopicolide, active component B, dispersant, wetting agent, filler mixing, mix homogeneously in mixed cylinder, through air-flow
Pulverizer remixes uniformly after pulverizing, and i.e. can be made into wettable powder product of the present invention.Specifically it is shown in Table 1,2.
Table 1 embodiment 1～6 each component and content
Table 2 embodiment 7～12 each component and content
Embodiment 13～24 water dispersible granules
Fluopicolide, active component B, dispersant, wetting agent, disintegrating agent, filler etc. are needed through comminution by gas stream together
The particle diameter wanted, adds other auxiliary agents such as binding agent (can add and can be not added with), obtains granulation materials.Item is quantitatively sent into fluid bed
Through pelletizing and dried in granulating drier, can be prepared by water dispersible granules product of the present invention, be specifically shown in Table 3,4.
Table 3 embodiment 13～18 each component and content
Table 4 embodiment 19～24 each component and content
Embodiment 25～36 suspending agent
By dispersant, wetting agent, defoamer, thickening agent (can add and can be not added with), antifreeze (can add and can be not added with), through at a high speed
Shear-mixed is uniform, adds fluopicolide, active component B, ball milling 2～3 hours in ball mill, makes diameter of particle all at 5 μ
Below m, surplus deionized water is supplied, and can be prepared by suspending agent product of the present invention, is specifically shown in Table 5,6.
Table 5 embodiment 25～30 each component and content
Table 6 embodiment 31～36 each component and content
Embodiment 37～48 aqueous emulsion
Fluopicolide, active component B, solvent, emulsifying agent are added together, make to be dissolved into homogeneous oil phase；By deionized water,
Antifreeze (can add and can be not added with), thickening agent (can add and can be not added with), defoamer mix, and become homogeneous aqueous phase.In high-speed stirred
Under, aqueous phase is added oil phase, prepares aqueous emulsion product of the present invention.Specifically it is shown in Table 7,8.
Table 7 embodiment 37～42 each component and content
Table 8 embodiment 43～48 each component and content
Embodiment 49～54 microemulsion
Being dissolved in fluopicolide, active component B equipped with in the homogenizer of solvent, by emulsifying agent, antifreeze, (can add can not
Add), defoamer, join in the homogenizer equipped with above-mentioned solution, surplus deionized water mixes and even after supplying strongly
Change, finally obtain the microemulsion product of the present invention that clear appearance is transparent.Specifically it is shown in Table 9.
Table 9 embodiment 49～54 each component and content
Embodiment 55～60 suspension emulsion
Dispersant, defoamer, thickening agent (can add and can be not added with), antifreeze (can add and can be not added with) are mixed through high speed shear
Uniformly, add fluopicolide, ball milling 2～3 hours in ball mill, make diameter of particle all below 5 μm, prepare fluopicolide
Suspending agent, then by active component B, emulsifying agent, solvent and the various direct emulsifying of auxiliary agent high speed agitator to suspending agent, makes
Obtain suspension emulsion product of the present invention.Specifically it is shown in Table 10.
Table 10 embodiment 55～60 each component and content
Trifloxystrobin, fluoxastrobin, Enestroburin, ZEN 90160, kresoxim-methyl in table 1～10 are exchanged, brand-new can be prepared
Agent.
Embodiment 61～63 microcapsule suspending agent
By fluopicolide, active component B, macromolecule cyst material, solvent mixing, make to be dissolved into homogeneous oil phase, shearing
Under the conditions of, oil phase is joined containing emulsifying agent, pH adjusting agent, dispersant, defoamer aqueous phase solution in, surplus deionization
Water is supplied, and bi-material reacts at oil-water interfaces, forms macromolecule cyst wall, makes the present composition finely disseminated micro-
Capsule suspending agent product.Specifically it is shown in Table 11.
Table 11 embodiment 61～63 each component and content
Embodiment 64～66 microcapsule suspension-suspendinagent agent
By active component B, macromolecule cyst material, solvent mixing, make to be dissolved into homogeneous oil phase, by oil phase at shearing condition
Under join containing emulsifying agent, pH adjusting agent aqueous phase solution in, make finely disseminated microcapsule suspending agent.By dispersant, wet
Profit agent, defoamer, thickening agent (can add and can be not added with), through high speed shear mix homogeneously, add fluopicolide, ball in ball mill
Grind 2～3 hours, make diameter of particle all below 5 μm, prepare suspending agent, then suspending agent is joined micro-capsule suspension
Aqueous phase solution in, deionized water supplies surplus, makes the present composition finely disseminated microcapsule suspension-suspendinagent agent product.
Specifically it is shown in Table 12.
Table 12 embodiment 64～66 each component and content
The embodiment of the present invention is the method using Toxicity Determination and field test to combine.First pass through indoor virulence to survey
Fixed, after clear and definite two kinds of medicaments are compounding by a certain percentage potentiation ratio (SR), SR ＜ 0.5 is antagonism, 0.5≤SR≤1.5
For summation action, SR ＞ 1.5 is potentiation, on this basis, then carries out field test.
Test method: after prerun determines each medicament effective inhibition concentration scope, medicament is set 5 respectively by active constituent content
Individual dosage processes, if clear water comparison.Carry out with reference to " farm-chemical indoor determination test rule antibacterial ", use mycelial growth speed
Rate method measures the medicament virulence to crop pathogenic bacteria.Measure colony diameter by decussation method after 72h, calculate each process and only grow
Amount, mycelial growth inhibition rate.
Net growth (mm)=measurement colony diameter-5
Mycelial growth inhibition rate is converted into probit value (y), and liquor strength (μ g/mL) is converted into logarithm value (x), with minimum
Square law tries to achieve virulence regression equation (y=a+bx), and thus calculates the EC of every kind of medicament50Value.Simultaneously according to Wadley method
Calculating two medicaments different ratio synergy ratio (SR), SR ＜ 0.5 is antagonism, and 0.5≤SR≤1.5 are summation action,
SR ＞ 1.5 is potentiation.Computing formula is as follows:
Wherein: a, b are respectively the ratio that active components A is shared in combination with active component B；
A is fluopicolide；
B plants selected from one of trifloxystrobin, fluoxastrobin, Enestroburin, ZEN 90160, kresoxim-methyl.
Application Example two:
For examination disease: cucumber downy mildew
Test medicine is provided by Shaanxi Meibang Pesticide Co., Ltd..
EXPERIMENTAL DESIGN: determine that fluopicolide is dense with the effectively suppression of both trifloxystrobin different ratio mixture through pilot study
Degree scope.
Toxicity test result
Table 13 fluopicolide toxicity test analysis of results table to cucumber downy mildew compounding with trifloxystrobin
As shown in Table 13, fluopicolide and trifloxystrobin compound the proportioning of preventing and treating cucumber downy mildew when 1 80～60 1, increase
Effect ratio SR is all higher than 1.5, illustrates that both all show potentiation, fluopicolide and oxime at mixture in the range of 1 80～60 1
The proportioning of bacterium ester is 1: 20～10: 1, and potentiation is the most prominent, and potentiation ratio is all more than 2.10；Fluopicolide and trifloxystrobin
When weight ratio is 1:2, potentiation ratio is maximum, and potentiation is the most obvious.Test through applicant and find fluopicolide and trifloxystrobin
Proportioning is 10 1,91,81,71,61,51,41,31,21,11,12,13,14,15,16,17,18,1
9,1 10,1 15,1 20 time to downy mildew, peronospora tabacina, early blight, late blight, gray mold, powdery mildew, rice blast, rust,
White rot, scab, glume blight, net blotch, leaf blight, brown spot, moire disease, anthrax, spot defoliation, damping off anti-
Having controlled obvious potentiation, potentiation ratio is all more than 1.50.
Application Example three:
For examination disease: downy mildew of garpe
Test medicine is provided by Shaanxi Meibang Pesticide Co., Ltd..
EXPERIMENTAL DESIGN: determine having of the former medicine of fluopicolide and fluoxastrobin and the two different ratio mixture through pilot study
Effect inhibition concentration scope
Toxicity test result
Table 14 fluopicolide toxicity test analysis of results table to downy mildew of garpe compounding with fluoxastrobin
As shown in Table 14, fluopicolide and fluoxastrobin compound the proportioning preventing and treating downy mildew of garpe when 1 80～60 1,
Potentiation ratio SR is all higher than 1.5, illustrates that both all show potentiation at mixtures in the range of 1 80～60 1, fluopicolide with
The proportioning of fluoxastrobin is 1 20～10: 1, and potentiation is the most prominent, and potentiation ratio is all more than 2.30；Fluopicolide and fluorine
When Fluoxastrobin weight ratio is 1:2, potentiation ratio is maximum, and potentiation is the most obvious.Discovery fluopicolide and fluorine is tested through applicant
The proportioning of Fluoxastrobin is 10 1,91,81,71,61,51,41,31,21,11,12,13,14,15,16,1
7,18,19,1 10,1 15,1 20 time to downy mildew, peronospora tabacina, early blight, late blight, gray mold, powdery mildew, rice blast
Disease, rust, white rot, scab, glume blight, net blotch, leaf blight, brown spot, moire disease, anthrax, spot defoliation, sudden
Sick preventing and treating of falling has obvious potentiation, and potentiation ratio is all more than 1.50.
Application Example four:
For examination disease: early blight of tomato
Test medicine is provided by Shaanxi Meibang Pesticide Co., Ltd..
EXPERIMENTAL DESIGN: determine having of the former medicine of fluopicolide and Enestroburin and the two different ratio mixture through pilot study
Effect inhibition concentration scope.
Toxicity test result
Table 15 fluopicolide toxicity test analysis of results table to early blight of tomato compounding with Enestroburin
As shown in Table 15, fluopicolide and Enestroburin compound the proportioning preventing and treating early blight of tomato when 1 80～60 1,
Potentiation ratio SR is all higher than 1.5, illustrates that both all show potentiation at mixtures in the range of 1 80～60 1, fluopicolide with
The proportioning of Enestroburin is 1: 20～10: 1, and potentiation is the most prominent, and potentiation ratio is all more than 2.20；Fluopicolide and alkene
When trifloxystrobin weight ratio is 1:2, potentiation ratio is maximum, and potentiation is the most obvious.Discovery fluopicolide and alkene is tested through applicant
The proportioning of trifloxystrobin is 10 1,91,81,71,61,51,41,31,21,11,12,13,14,15,16,1
7,18,19,1 10,1 15,1 20 time to downy mildew, peronospora tabacina, early blight, late blight, gray mold, powdery mildew, rice blast
Disease, rust, white rot, scab, glume blight, net blotch, leaf blight, brown spot, moire disease, anthrax, spot defoliation, sudden
Sick preventing and treating of falling has obvious potentiation, and potentiation ratio is all more than 1.50.
Application Example five:
For examination disease: Fructus Capsici damping off
Test medicine is provided by Shaanxi Meibang Pesticide Co., Ltd..
EXPERIMENTAL DESIGN: determine having of the former medicine of fluopicolide and ZEN 90160 and the two different ratio mixture through pilot study
Effect inhibition concentration scope.
Toxicity test result
Table 16 fluopicolide toxicity test analysis of results table to Fructus Capsici damping off compounding with ZEN 90160
As shown in Table 16, fluopicolide and ZEN 90160 compound the proportioning of preventing and treating Fructus Capsici damping off when 1 80～60 1,
Potentiation ratio SR is all higher than 1.5, illustrates that both all show potentiation at mixtures in the range of 1 80～60 1, fluopicolide with
The proportioning of ZEN 90160 is 1: 30～10: 1, and potentiation is the most prominent, and potentiation ratio is all more than 2.10；Fluopicolide and pyridine
When oxygen bacterium ester weight ratio is 1:3, potentiation ratio is maximum, and potentiation is the most obvious.Discovery fluopicolide and pyridine is tested through applicant
The proportioning of oxygen bacterium ester is 10 1,51,41,31,21,11,12,13,14,15,16,17,18,19,1 10,
To downy mildew, peronospora tabacina, early blight, late blight, gray mold, powdery mildew, rice blast, rust when 1 15,1 20,1 25,1 30
Disease, white rot, scab, glume blight, net blotch, leaf blight, brown spot, moire disease, anthrax, spot defoliation, damping off
Preventing and treating have obvious potentiation, potentiation ratio is all more than 1.50.
Application Example six:
For examination disease: the late blight of potato
Test medicine is provided by Shaanxi Meibang Pesticide Co., Ltd..
EXPERIMENTAL DESIGN: determine having of the former medicine of fluopicolide and kresoxim-methyl and the two different ratio mixture through pilot study
Effect inhibition concentration scope.
Table 17 fluopicolide toxicity test analysis of results table to the late blight of potato compounding with kresoxim-methyl
As shown in Table 17, fluopicolide and kresoxim-methyl compound the proportioning preventing and treating the late blight of potato 1 80～60 1
Time, potentiation ratio SR is all higher than 1.5, illustrates that both all show potentiation, fluorine pyrrole bacterium at mixture in the range of 1 80～60 1
The proportioning of amine and kresoxim-methyl is 1: 20～10: 1, and potentiation is the most prominent, and potentiation ratio is all more than 2.20；Fluopicolide
When being 1:2 with kresoxim-methyl weight ratio, potentiation ratio is maximum, and potentiation is the most obvious.Discovery fluopicolide is tested through applicant
It is 10 1,91,81,71,61,51,41,31,21,11,12,13,14,15,1 with the proportioning of kresoxim-methyl
6,17,18,19,1 10,1 15,1 20 time to downy mildew, peronospora tabacina, early blight, late blight, gray mold, powdery mildew,
Rice blast, rust, white rot, scab, glume blight, net blotch, leaf blight, brown spot, moire disease, anthrax, speckle are fallen leaves
Sick, the preventing and treating of damping off has obvious potentiation, and potentiation ratio is all more than 1.50.
Application Example seven fluopicolide and active component B and compounding prevent and treat the late blight of potato test of pesticide effectiveness
This experimental establishment is at Shaanxi Province's Weinan City, and test medicine is researched and developed by Shaanxi Meibang Pesticide Co., Ltd., provided, comparison
10% fluopicolide suspending agent (autogamy), 25% trifloxystrobin suspending agent (commercial), 10% fluoxastrobin suspending agent (autogamy), 25%
Enestroburin suspending agent (commercial), 25% ZEN 90160 suspending agent (autogamy), 20% kresoxim-methyl wettable powder (autogamy).
Investigating the late blight of potato state of an illness before medicine, in the dispenser for the first time of state of an illness initial stage, dispenser in every 7 days once, is total to dispenser 2
Secondary.Within after dispenser 3 days, 7 days, 15 days for the second time, investigate disease index respectively and calculate preventive effect.Experimental result is as follows:
Table 18 fluopicolide and active component B and compounding prevent and treat the late blight of potato test of pesticide effectiveness
As can be seen from Table 18, fluopicolide and active component B and compounding after can effectively prevent and treat the late blight of potato, anti-
Control effect and be superior to the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example eight fluopicolide and active component B and compounding prevent and treat the downy mildew of garpe test of pesticide effectiveness
This test arrangement is at Shaanxi Province's Weinan City, and test medicine is researched and developed by Shaanxi Meibang Pesticide Co., Ltd., provided, comparison
10% fluopicolide suspending agent (autogamy), 25% trifloxystrobin suspending agent (commercial), 10% fluoxastrobin suspending agent (autogamy), 25%
Enestroburin suspending agent (commercial), 25% ZEN 90160 suspending agent (autogamy), 20% kresoxim-methyl wettable powder (autogamy).
Investigating the downy mildew of garpe state of an illness before medicine, in the dispenser for the first time of state of an illness initial stage, dispenser in every 7 days once, is total to dispenser 2 times.
Within after dispenser 3 days, 7 days, 15 days for the second time, investigate disease index respectively and calculate preventive effect.Experimental result is as follows:
Table 19 fluopicolide and active component B and compounding prevent and treat the downy mildew of garpe test of pesticide effectiveness
As can be seen from Table 19, fluopicolide and active component B and compounding after can effectively prevent and treat downy mildew of garpe, preventing and treating
Effect is superior to the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example nine fluopicolide and active component B and the compounding preventing and treating Chinese cabbage downy mildew test of pesticide effectiveness thereof
This test arrangement is at Shaanxi Province's Weinan City, and test medicine is researched and developed by Shaanxi Meibang Pesticide Co., Ltd., provided, comparison
10% fluopicolide suspending agent (autogamy), 25% trifloxystrobin suspending agent (commercial), 10% fluoxastrobin suspending agent (autogamy), 25%
Enestroburin suspending agent (commercial), 25% ZEN 90160 suspending agent (autogamy), 20% kresoxim-methyl wettable powder (autogamy).
Investigating the Chinese cabbage downy mildew state of an illness before medicine, in the dispenser for the first time of state of an illness initial stage, dispenser in every 7 days once, is total to dispenser 2 times.
Within after dispenser 7 days, 14 days, 30 days for the second time, investigate disease index respectively and calculate preventive effect.Experimental result is as follows:
Table 20 fluopicolide and active component B and the compounding preventing and treating Chinese cabbage downy mildew test of pesticide effectiveness thereof
As can be seen from Table 20, fluopicolide and active component B and compounding after can effectively prevent and treat Chinese cabbage downy mildew, preventing and treating
Effect is superior to the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example ten fluopicolide and active component B and the compounding preventing and treating peronophythora litchi test of pesticide effectiveness thereof
This test arrangement is in Zengcheng City of Guangdong Province, and test medicine is researched and developed by Shaanxi Meibang Pesticide Co., Ltd., provided, comparison
10% fluopicolide suspending agent (autogamy), 25% trifloxystrobin suspending agent (commercial), 10% fluoxastrobin suspending agent (autogamy), 25%
Enestroburin suspending agent (commercial), 25% ZEN 90160 suspending agent (autogamy), 20% kresoxim-methyl wettable powder (autogamy).
The investigation peronophythora litchi state of an illness, in the dispenser for the first time of state of an illness initial stage, dispenser in every 7 days once, is total to dispenser 2 times.The
Within after secondary dispenser 7 days, 14 days, 30 days, investigate disease index respectively and calculate preventive effect.Experimental result is as follows:
Table 21 fluopicolide and active component B and the compounding preventing and treating peronophythora litchi test of pesticide effectiveness thereof
As can be seen from Table 21, fluopicolide and active component B and compounding after can effectively prevent and treat peronophythora litchi, anti-
Control effect and be superior to the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example 11 fluopicolide and active component B and compounding prevent and treat the early blight of tomato test of pesticide effectiveness
This experimental establishment is at Shaanxi Province's Weinan City, and test medicine is researched and developed by Shaanxi Meibang Pesticide Co., Ltd., provided, comparison
10% fluopicolide suspending agent (autogamy), 25% trifloxystrobin suspending agent (commercial), 10% fluoxastrobin suspending agent (autogamy), 25%
Enestroburin suspending agent (commercial), 25% ZEN 90160 suspending agent (autogamy), 20% kresoxim-methyl wettable powder (autogamy).
Investigating the early blight of tomato state of an illness before medicine, in the dispenser for the first time of state of an illness initial stage, dispenser in every 7 days once, is total to dispenser 2 times.
Within after dispenser 7 days, 14 days, 30 days for the second time, investigate disease index respectively and calculate preventive effect.Experimental result is as follows:
Table 22 fluopicolide and active component B and compounding prevent and treat the early blight of tomato test of pesticide effectiveness
As can be seen from Table 22, fluopicolide and active component B and compounding after can effectively prevent and treat early blight of tomato, preventing and treating
Effect is superior to the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example 12 fluopicolide and active component B and the compounding preventing and treating Fructus Cucumidis sativi damping off test of pesticide effectiveness thereof
This test arrangement is in Jingyang County, Shaanxi Province, and test medicine is researched and developed by Shaanxi Meibang Pesticide Co., Ltd., provided, comparison
10% fluopicolide suspending agent (autogamy), 25% trifloxystrobin suspending agent (commercial), 10% fluoxastrobin suspending agent (autogamy), 25%
Enestroburin suspending agent (commercial), 25% ZEN 90160 suspending agent (autogamy), 20% kresoxim-methyl wettable powder (autogamy).
Investigating the Fructus Cucumidis sativi damping off state of an illness before medicine, in the dispenser for the first time of state of an illness initial stage, dispenser in every 7 days once, is total to dispenser 2 times.
Within after dispenser 7 days, 14 days, 30 days for the second time, investigate disease index respectively and calculate preventive effect.Experimental result is as follows:
Table 23 fluopicolide and active component B and the compounding preventing and treating Fructus Cucumidis sativi damping off test of pesticide effectiveness thereof
As can be seen from Table 23, fluopicolide and active component B and compounding after can effectively prevent and treat Fructus Cucumidis sativi damping off, preventing and treating
Effect is superior to the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
After draw through tests different local throughout the country, fluopicolide and trifloxystrobin, fluoxastrobin, alkene oxime bacterium
After ester, ZEN 90160, kresoxim-methyl are compounding to the downy mildew in various crop, peronospora tabacina, early blight, late blight, gray mold,
Powdery mildew, rice blast, rust, white rot, scab, glume blight, net blotch, leaf blight, brown spot, moire disease, anthrax, speckle
The preventive effect of the some Common Diseases such as defoliation, damping off all 95% with on excellent, in single dose preventive effect, potentiation is obvious.
Claims (6)
1. the bactericidal composition of a containing fluopicolide and methoxy acrylic, it is characterised in that: containing active components A with
Active component B, active components A and active component B weight ratio are 1: 80～60: 1, and described active components A is selected from fluopicolide,
Active component B plants selected from one of trifloxystrobin, ZEN 90160, kresoxim-methyl.
Containing fluopicolide the most according to claim 1 and the bactericidal composition of methoxy acrylic, it is characterised in that:
Active components A is 1: 60～40: 1 with the weight ratio of active component B.
Containing fluopicolide the most according to claim 2 and the bactericidal composition of methoxy acrylic, it is characterised in that:
Fluopicolide is 1: 20～10: 1 with the weight ratio of trifloxystrobin；
Fluopicolide is 1: 30～10: 1 with the weight ratio of ZEN 90160；
Fluopicolide is 1: 20～10: 1 with the weight ratio of kresoxim-methyl.
4. according to the bactericidal composition of the containing fluopicolide according to any one of claims 1 to 3 Yu methoxy acrylic,
It is characterized in that: compositions make wettable powder, water dispersible granules, suspending agent, aqueous emulsion, microemulsion, suspension emulsion, microcapsule hang
Floating agent, microcapsule suspension-suspendinagent agent.
Containing fluopicolide the most according to claim 4 is used for preventing and treating crop with the bactericidal composition of methoxy acrylic
The purposes of disease.
Purposes the most according to claim 5, it is characterised in that: described disease includes downy mildew, peronospora tabacina, early epidemic
Disease, late blight, gray mold, powdery mildew, rice blast, rust, white rot, scab, glume blight, net blotch, leaf blight, brown patch
Disease, moire disease, anthrax, spot defoliation, damping off.
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| CN201610653482.XA CN106234367A (en) | 2012-06-13 | 2012-06-13 | A kind of containing fluopicolide and the bactericidal composition of methoxy acrylic |
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| CN201610653482.XA CN106234367A (en) | 2012-06-13 | 2012-06-13 | A kind of containing fluopicolide and the bactericidal composition of methoxy acrylic |
| CN201210194378.0A CN103478133A (en) | 2012-06-13 | 2012-06-13 | Sterilization composition containing fluopicolide and methoxy acrylate |
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| CN103004819A (en) * | 2012-11-30 | 2013-04-03 | 王学权 | Fluopicolide-containing bactericide composition |
| CN107771808A (en) * | 2016-08-29 | 2018-03-09 | 南京华洲药业有限公司 | A kind of bactericidal composition and its application containing ZEN 90160 and fluopicolide |
| CN106879595A (en) * | 2017-04-13 | 2017-06-23 | 青岛瀚生生物科技股份有限公司 | Bactericidal composition and its application |
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| CN101822263A (en) * | 2010-01-27 | 2010-09-08 | 深圳诺普信农化股份有限公司 | Sterilization compound containing ZJ0712 |
| CN102696614A (en) * | 2012-05-10 | 2012-10-03 | 永农生物科学有限公司 | Trifloxystrobin-containing compound pesticide bactericidal composition and preparation |
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| TW575562B (en) * | 1998-02-19 | 2004-02-11 | Agrevo Uk Ltd | Fungicides |
| DE102004049761A1 (en) * | 2004-10-12 | 2006-04-13 | Bayer Cropscience Ag | Fungicidal drug combinations |
| CN101080169A (en) * | 2004-12-23 | 2007-11-28 | 巴斯福股份公司 | Fungicide composition |
| GB0812028D0 (en) * | 2008-07-01 | 2008-08-06 | Syngenta Participations Ag | Fungicidal compositions |
| CN101647446A (en) * | 2009-06-22 | 2010-02-17 | 陕西标正作物科学有限公司 | Bactericidal composite with fluopicolide and dimethomorph |
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| CN101822263A (en) * | 2010-01-27 | 2010-09-08 | 深圳诺普信农化股份有限公司 | Sterilization compound containing ZJ0712 |
| CN102696614A (en) * | 2012-05-10 | 2012-10-03 | 永农生物科学有限公司 | Trifloxystrobin-containing compound pesticide bactericidal composition and preparation |
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