CN105340932A - Bactericidal composition containing fluopyram - Google Patents
Bactericidal composition containing fluopyram Download PDFInfo
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- CN105340932A CN105340932A CN201510614135.1A CN201510614135A CN105340932A CN 105340932 A CN105340932 A CN 105340932A CN 201510614135 A CN201510614135 A CN 201510614135A CN 105340932 A CN105340932 A CN 105340932A
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- acid amides
- pyrrole bacterium
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- bacterium acid
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
- A01N47/28—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N<
- A01N47/34—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N< containing the groups, e.g. biuret; Thio analogues thereof; Urea-aldehyde condensation products
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
- A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/50—1,3-Diazoles; Hydrogenated 1,3-diazoles
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
- A01N43/84—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms six-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,4
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
- A01N47/10—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof
- A01N47/12—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof containing a —O—CO—N< group, or a thio analogue thereof, neither directly attached to a ring nor the nitrogen atom being a member of a heterocyclic ring
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- Pest Control & Pesticides (AREA)
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- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
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- General Health & Medical Sciences (AREA)
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Abstract
The present invention discloses a bactericidal composition containing fluopyram. The bactericidal composition comprises an active component A and an active component B, wherein the active component A is selected from fluopyram, and the active component B is an optional component selected from the following compounds: cyazofamid, dimethomorph, metalaxyl or salt thereof, cymoxanil and iprovalicarb, and the weight ratio of the active component A and the active component B is 1:80-60:1. The composition provided by the present invention has relatively high activity on multiple types of diseases of multiple types of crops, has the significant synergistic effect and expands a bactericidal spectrum; and the bactericidal composition has the characteristics of low dosage, rain erosion resistance and significant synergistic effects.
Description
The application is divisional application, and original application is the application for a patent for invention that Shaanxi Meibang Pesticide Co., Ltd. proposes, and application number is: 201210231590.X, and application name is called: a kind of bactericidal composition of containing fluopyram, the date of application is: 2012.7.5.
Technical field
The invention belongs to technical field of pesticide, relate to or the application of bactericidal composition in crop pest of its a kind of containing fluopyram.
Technical background
Fluorine pyrrole bacterium acid amides (Fluopyram) chemical name: N-{2-[the chloro-5-of 3-(trifluoromethyl)-2-pyridine radicals) ethyl] the fluoro-0-toluamide of-α, α, α-three, molecular formula: C
16h
11clF
6n
2o, it suppresses mitochondrial respiratory by hindering the electro transfer of succinate dehydrogenase in respiratory chain.Reaching the object controlling pathogenic bacteria by suppressing the several stage in the growth of pathogenic bacteria cycle, being mainly used in broad leaf crop being prevented and treated the microbial disease of ascus.
Cyazofamid, dimethomorph, metalaxyl or its salt, white urea cyanogen, iprovalicarb are all some common bactericide, and the salt of metalaxyl is Metalaxyl-M, and Metalaxyl-M has the bactericidal activity being better than metalaxyl, is agriculturally being widely used.
But in the real process of agricultural production, the problem that controlling disease the most easily produces is drug-fast generation.Different cultivars composition carries out composite, is to prevent and treat the very common method of resistance.Heterogeneity is carried out composite, according to practical application effect, judge certain composite be synergy, add and or antagonism.In most cases, the composite effect of agricultural chemicals is all additive effect, really has the seldom composite of synergistic effect, especially synergistic effect clearly, very high composite just less of co-toxicity coefficient.Study through inventor, find fluorine pyrrole bacterium acid amides and cyazofamid, dimethomorph, metalaxyl or its salt, white urea cyanogen, iprovalicarb is composite after can produce good synergistic effect, and not yet open about the relevant report that fluorine pyrrole bacterium acid amides and cyazofamid, dimethomorph, metalaxyl or its salt, white urea cyanogen, iprovalicarb are composite.
Summary of the invention
The object of the invention is to propose a kind of bactericidal composition with synergistic function, use cost is low, preventive effect is good containing fluopyram.
The bactericidal composition of the containing fluopyram that the present invention proposes contains active components A and active component B, active components A and active component B weight ratio are 1 ︰ 80 ~ 60 ︰ 1, described active components A is selected from fluorine pyrrole bacterium acid amides, and active component B is selected from the one in cyazofamid, dimethomorph, metalaxyl or its salt, white urea cyanogen, iprovalicarb.Active components A and active component B preferably weight ratio are 1 ︰ 60 ~ 40 ︰ 1; The weight ratio being more preferably fluorine pyrrole bacterium acid amides and cyazofamid is 1 ︰ 30 ~ 15 ︰ 1, the weight ratio of fluorine pyrrole bacterium acid amides and dimethomorph is 1 ︰ 25 ~ 10 ︰ 1, the weight ratio of fluorine pyrrole bacterium acid amides and metalaxyl or its salt is 1 ︰ 30 ~ 5 ︰ 1, the weight ratio of fluorine pyrrole bacterium acid amides and white urea cyanogen is 1 ︰ 30 ~ 10 ︰ 1, and the weight ratio of fluorine pyrrole bacterium acid amides and iprovalicarb is 1 ︰ 30 ~ 10 ︰ 1; The weight ratio most preferably being fluorine pyrrole bacterium acid amides and cyazofamid is 1 ︰ 10 ~ 5 ︰ 1, the weight ratio of fluorine pyrrole bacterium acid amides and dimethomorph is 1 ︰ 15 ~ 5 ︰ 1, the weight ratio of fluorine pyrrole bacterium acid amides and metalaxyl or its salt is 1 ︰ 15 ~ 1 ︰ 1, the weight ratio of fluorine pyrrole bacterium acid amides and white urea cyanogen is 1 ︰ 15 ~ 5 ︰ 1, and the weight ratio of fluorine pyrrole bacterium acid amides and iprovalicarb is 1 ︰ 15 ~ 5 ︰ 1.
The bactericidal composition of the containing fluopyram that the present invention proposes is for preventing and treating the purposes of disease on crops, and described crops comprise cereal crops, legume crop, fiber crop, sugar [yielding, melon crop, fruits crop, dry fruit crop, hobby crop, root crop, oil crop, flower crop, medicinal crop, crop, green manure pasture crop; Described disease comprises downy mildew, peronospora tabacina, powdery mildew, epidemic disease, balck shank, damping off, mould maize ear rot, head blight, leaf mold, root rot, moire disease, leaf spot, net blotch, rust.
In the present composition, the content of active component depends on amount of application when being used alone, also depend on the mixed ratio of a kind of compound and another kind of compound with or its synergistic effect degree, simultaneously also relevant with target disease.In usual composition, the weight percentage of active component is 1% ~ 90% of gross weight, is preferably 5% ~ 80%.According to different preparation types, active component content scope is different.Usually, liquid preparation contains the active substance of by weight 1% ~ 60%, is preferably 5% ~ 50%; Solid pharmaceutical preparation contains the active substance of by weight 5% ~ 80%, is preferably 10% ~ 80%.
At least containing a kind of surfactant in bactericidal composition of the present invention, the dispersion of active component in water when being beneficial to use.Surface-active contents is 2% ~ 30% of total formulation weight amount, and surplus is solid or liquid diluent.
Surfactant selected by bactericidal composition of the present invention is known in those skilled in the art: can be selected from one or more in dispersant, wetting agent, thickener or defoamer.According to different dosage form, in preparation, stabilizing agent known in those skilled in the art, antifreeze etc. can also be contained.
Bactericidal composition of the present invention can by user before use through diluting or directly using.Its preparation can be prepared by processing method known in those skilled in the art, after mixing, then adds surfactant as one or more in dispersant, stabilizing agent, wetting agent, binding agent, defoamer etc. by active component with liquid flux or solid carrier.
Bactericidal composition of the present invention, can be processed into acceptable formulation on any agricultural chemicals on demand, and wherein preferred dosage form is wetting powder, water dispersible granules, suspending agent, suspension emulsion, aqueous emulsion, microemulsion, microcapsule suspending agent, microcapsule suspension-suspendinagent agent.
Composition comprises following component or its content when making wetting powder: active components A 1% ~ 60%, active component B1% ~ 80%, dispersant 2% ~ 10%, wetting agent 2% ~ 10%, filler surplus.
Composition comprises following component or its content when making water dispersible granules: active components A 1% ~ 60%, active component B1% ~ 80%, dispersant 3% ~ 12%, wetting agent 1% ~ 8%, disintegrant 1% ~ 10%, binding agent 0 ~ 8%, filler surplus.
Composition comprises following component or its content when making suspending agent: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, dispersant 2% ~ 10%, wetting agent 2% ~ 10%, defoamer 0.01% ~ 2%, thickener 0 ~ 2%, antifreeze 0 ~ 8%, deionized water add to 100%.
Composition comprises following component or its content when making suspension emulsion: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, emulsifier 2% ~ 12%, dispersant 2% ~ 10%, solvent 1% ~ 15%, defoamer 0.01% ~ 2%, thickener 0 ~ 2%, antifreeze 0 ~ 8%, deionized water add to 100%.
Composition comprises following component or its content when making aqueous emulsion: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, solvent 1% ~ 30%, emulsifier 1% ~ 15%, antifreeze 0 ~ 8%, defoamer 0.01% ~ 2%, thickener 0 ~ 2%, deionized water add to 100%.
Composition comprises following component or its content when making microemulsion: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, emulsifier 3% ~ 25%, solvent 1% ~ 30%, antifreeze 0 ~ 8%, defoamer 0.01% ~ 2%, deionized water add to 100%.
Composition comprises following component or its content when making microcapsule suspending agent: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, macromolecule cyst material 2% ~ 10%, dispersant 1% ~ 10%, solvent 1% ~ 10%, emulsifier 1% ~ 7%, pH adjusting agent 0.01% ~ 5%, defoamer 0.01% ~ 2%, deionized water add to 100%.
Composition comprises following component or its content when making microcapsule suspension-suspendinagent agent: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, macromolecule cyst material 2% ~ 10%, dispersant 1% ~ 12%, wetting agent 1% ~ 8%, organic solvent 1% ~ 15%, emulsifier 1% ~ 6%, defoamer 0.01% ~ 2%, thickener 0 ~ 2%, pH adjusting agent 0.01% ~ 5%, deionized water add to 100%.
Wetting powder the key technical indexes of the present invention:
Water dispersible granules the key technical indexes of the present invention:
Suspending agent the key technical indexes of the present invention:
Suspension emulsion the key technical indexes of the present invention:
Aqueous emulsion the key technical indexes of the present invention:
Microemulsion the key technical indexes of the present invention:
Microcapsule suspending agent the key technical indexes of the present invention:
Microcapsule suspension-suspendinagent agent the key technical indexes of the present invention:
The invention has the advantages that:
(1) present composition has good synergy and lasting effect within the specific limits, and preventive effect is higher than single dose; (2) pesticide usage amount reduces, and reduces the residual quantity of agricultural chemicals on crop, alleviates environmental pollution; (3) fungicidal spectrum is expanded, to multiple diseases as downy mildew, peronospora tabacina, powdery mildew, epidemic disease, balck shank, damping off, mould maize ear rot, head blight, leaf mold, root rot, moire disease, leaf spot, net blotch, rust have greater activity.
Embodiment
Below in conjunction with embodiment to further instruction of the present invention, the percentage in embodiment is all weight percentage, but the present invention is not limited thereto.
Application Example one:
Example 1 ~ 12 wetting powder
By fluorine pyrrole bacterium acid amides, active component B, dispersant, wetting agent, filler mixing, mix in mixed cylinder, mix again after airslide disintegrating mill is pulverized, namely can be made into wetting powder product of the present invention.Specifically in table 1.
The each component of table 1 example 1 ~ 12 or its content
Cyazofamid, dimethomorph, metalaxyl or its salt, white urea cyanogen, iprovalicarb in table 1 are exchanged, can novel formulation be obtained.
Example 13 ~ 24 water dispersible granules
Fluorine pyrrole bacterium acid amides, active component B, dispersant, wetting agent, binding agent (can add and can not add), disintegrant, filler are obtained together the particle diameter of needs through air-flow crushing, obtain granulation materials.Item is quantitatively sent in fluidized bed granulating dryer through granulating or after its drying, obtaining water dispersible granules product of the present invention.Specifically in table 2.
The each component of table 2 example 13 ~ 24 or its content
Example 25 ~ 36 suspending agent
Dispersant, wetting agent, defoamer, thickener (can add and can not add), antifreeze (can add and can not add) are mixed through high speed shear, add fluorine pyrrole bacterium acid amides, active component B, surplus deionized water is supplied, ball milling 2 ~ 3 hours in ball mill, make diameter of particle all below 5 μm, obtained suspending agent product of the present invention.Specifically in table 3.
The each component of table 3 example 25 ~ 36 or its content
Active component B cyazofamid, dimethomorph, metalaxyl, white urea cyanogen, iprovalicarb in table 2,3 are exchanged, can novel formulation be obtained.
Example 37 ~ 43 suspension emulsion
By dispersant, defoamer, thickener (can add and can not add), antifreeze (can add and can not add) in above-mentioned formulation material, mix through high speed shear, add fluorine pyrrole bacterium acid amides, ball milling 2 ~ 3 hours in ball mill, make diameter of particle all below 5 μm, obtained fluorine pyrrole bacterium amide suspending agents, then by active component B, solvent, emulsifier or the direct emulsification of its various auxiliary agent high speed agitators in suspending agent, obtained suspension emulsion product of the present invention, specifically in table 4,5.
The each component of table 4 example 37 ~ 39 or its content
The each component of table 5 example 40 ~ 43 or its content
Example 44 ~ 54 aqueous emulsion
Fluorine pyrrole bacterium acid amides, active component B, solvent, emulsifier are added together, make to be dissolved into homogeneous oil phase; Deionized water, antifreeze (can add and can not add), thickener (can add and can not add), defoamer are mixed, becomes homogeneous aqueous phase.Under high velocity agitation, aqueous phase is added oil phase, obtained aqueous emulsion product of the present invention.Specifically in table 6.
The each component of table 6 example 44 ~ 50 or its content
Active component B cyazofamid, dimethomorph, metalaxyl or its salt, white urea cyanogen, iprovalicarb in table 4 ~ 6 are exchanged, can novel formulation be obtained.
Example 55 ~ 57 microemulsion
Fluorine pyrrole bacterium acid amides, active component B are dissolved in and are equipped with in the homogenizer of solvent, emulsifier, antifreeze (can add and can not add), defoamer are joined in the homogenizer that above-mentioned solution is housed, surplus deionized water gives strong mixing and homogenize after supplying, finally obtain the microemulsion product of the present invention that clear appearance is transparent.Specifically in table 7.
The each component of table 7 example 55 ~ 57 or its content
Example 58,59 microcapsule suspending agent
By fluorine pyrrole bacterium acid amides, active component B, macromolecule cyst material, solvent, make to be dissolved into homogeneous oil phase, in a shear condition, oil phase is joined in the aqueous phase solution containing emulsifier, pH adjusting agent, dispersant, defoamer, surplus deionized water is supplied, bi-material reacts at oil-water interfaces, forms macromolecule cyst wall, makes the finely disseminated microcapsule suspending agent product of the present composition.Specifically in table 8.
Table 8 example 58,59 each component or its content
Example 60,61 microcapsule suspension-suspendinagent agent
By active component B, macromolecule cyst material, solvent, make to be dissolved into homogeneous oil phase, oil phase is joined in a shear condition in the aqueous phase solution containing emulsifier, pH adjusting agent, make finely disseminated microcapsule suspending agent.Dispersant, wetting agent, defoamer, thickener (can add and can not add) are mixed through high speed shear, add fluorine pyrrole bacterium acid amides, ball milling 2 ~ 3 hours in ball mill, make diameter of particle all below 5 μm, obtained suspending agent, then join in the aqueous phase solution of micro-capsule suspension by suspending agent, deionized water supplies surplus, makes the finely disseminated microcapsule suspension-suspendinagent agent product of the present composition.Specifically in table 9.
Table 9 example 60,61 each component or its content
The embodiment of the present invention is the method adopting Toxicity Determination and field trial to combine.First pass through Toxicity Determination, synergy ratio (SR) after clear and definite two kinds of medicaments are composite by a certain percentage, SR < 0.5 is antagonism, 0.5≤SR≤1.5 are summation action, SR > 1.5 is synergistic effect, on this basis, then carry out field trial.
Test method: determine that after the effective inhibition concentration scope of each medicament, medicament establishes 5 dosage process respectively by active constituent content through prerun, if clear water contrast.Carry out with reference to " farm-chemical indoor determination test rule bactericide ", adopt mycelial growth rate method to measure medicament to the virulence of crop germ.Measure colony diameter by right-angled intersection method after 72h, calculate each process net growth, mycelial growth inhibition rate.
Net growth (mm)=measurement colony diameter-5
Mycelial growth inhibition rate is converted into probit value (y), liquor strength (μ g/mL) converts logarithm value (x) to, try to achieve virulence regression equation (y=a+bx) with method of least squares, and calculate the EC of often kind of medicament thus
50value.Calculate two medicament different ratio synergies ratio (SR) according to Wadley method, SR < 0.5 is antagonism, and 0.5≤SR≤1.5 are summation action simultaneously, and SR > 1.5 is synergistic effect.Computing formula is as follows:
Wherein: a, b are respectively active components A and the ratio of active component B shared by combination;
A is fluorine pyrrole bacterium acid amides;
B is selected from the one in cyazofamid, dimethomorph, metalaxyl or its salt, white urea cyanogen, iprovalicarb.
Application Example two:
For examination disease: tomato blight
Test medicine provides by Shaanxi Meibang Pesticide Co., Ltd..
Experimental scheme: through effective inhibition concentration scope of preliminary experiment determination fluorine pyrrole bacterium acid amides and the former medicine of cyazofamid or different ratio mixture both it.
Table 10 fluorine pyrrole bacterium acid amides and the composite toxicity test analysis of results table to tomato blight of cyazofamid
As shown in Table 10, fluorine pyrrole bacterium acid amides and cyazofamid proportioning are all greater than 1.5 when 1 ︰ 80 ~ 60 ︰ 1 to the synergy ratio SR of tomato blight, both explanations mixture in 1 ︰ 80 ~ 60 ︰ 1 scope all shows synergistic effect, when the proportioning of fluorine pyrrole bacterium acid amides and cyazofamid is at 1 ︰ 30 ~ 15 ︰ 1, synergistic effect is more outstanding, and synergy ratio is all more than 2.00.Testing through applicant the optimum ratio finding fluorine pyrrole bacterium acid amides and cyazofamid is 15:1,10:1,8:1,5:1,4:1,3:1,2:1,1:1,1:2,1:3,1:4,1:5,1:6,1:7,1:8,1:10,1:12,1:15,1:20,1:25,1:30, especially when fluorine pyrrole bacterium acid amides and cyazofamid weight ratio are 1:2, synergy ratio is maximum, and synergistic effect is the most obvious.
Application Example three:
For examination disease: litchi peronospora tabacina
Test medicine provides by Shaanxi Meibang Pesticide Co., Ltd..
Experimental scheme: through effective inhibition concentration scope of preliminary experiment determination fluorine pyrrole bacterium acid amides and the former medicine of dimethomorph or different ratio mixture both it.
Toxicity test result
Table 11 fluorine pyrrole bacterium acid amides and the composite toxicity test analysis of results table to litchi peronospora tabacina of dimethomorph
As shown in Table 11, fluorine pyrrole bacterium acid amides and dimethomorph proportioning are all greater than 1.5 when 1 ︰ 80 ~ 60 ︰ 1 to the synergy ratio SR of litchi peronospora tabacina, both explanations mixture in 1 ︰ 80 ~ 60 ︰ 1 scope all shows synergistic effect, when the proportioning of fluorine pyrrole bacterium acid amides and dimethomorph is at 1 ︰ 25 ~ 10 ︰ 1, synergistic effect is more obviously given prominence to, and synergy ratio is all more than 2.10.Testing through applicant the optimum ratio finding fluorine pyrrole bacterium acid amides and dimethomorph is 10:1,8:1,6:1,4:1,3:1,2:1,1:1,1:2,1:3,1:4,1:5,1:6,1:7,1:8,1:9,1:10,1:12,1:14,1:16,1:18,1:20,1:25, especially when fluorine pyrrole bacterium acid amides and dimethomorph weight ratio are 1:5, synergy ratio is maximum, and synergistic effect is the most obvious.
Application Example four:
For examination disease: cucumber downy mildew
Test medicine provides by Shaanxi Meibang Pesticide Co., Ltd..
Experimental scheme: through effective inhibition concentration scope of preliminary experiment determination fluorine pyrrole bacterium acid amides and metalaxyl or the former medicine of its salt or different ratio mixture both it.
Toxicity test result
Table 12 fluorine pyrrole bacterium acid amides and metalaxyl or the composite toxicity test analysis of results table to cucumber downy mildew of its salt
As shown in Table 12, fluorine pyrrole bacterium acid amides and metalaxyl or its salt proportioning are all greater than 1.5 when 1 ︰ 80 ~ 60 ︰ 1 to the synergy ratio SR of cucumber downy mildew, both explanations mixture in 1 ︰ 80 ~ 60 ︰ 1 scope all shows synergistic effect, when the proportioning of fluorine pyrrole bacterium acid amides and metalaxyl or its salt is at 1 ︰ 30 ~ 5 ︰ 1, synergistic effect is more obviously given prominence to, and synergy ratio is all more than 2.15.Testing through applicant the optimum ratio finding fluorine pyrrole bacterium acid amides and metalaxyl or its salt is 5:1,1:1,1:3,1:5,1:6,1:7,1:8,1:9,1:10,1:11,1:12,1:13,1:14,1:15,1:16,1:17,1:18,1:19,1:20,1:25,1:30, especially when fluorine pyrrole bacterium acid amides and metalaxyl or its salt weight ratio are 1:10, synergy ratio is maximum, and synergistic effect is the most obvious.
Application Example five:
For examination disease: downy mildew of garpe
Test medicine provides by Shaanxi Meibang Pesticide Co., Ltd..
Experimental scheme: through effective inhibition concentration scope of preliminary experiment determination fluorine pyrrole bacterium acid amides and the former medicine of white urea cyanogen or different ratio mixture both it.
Toxicity test result
Table 13 fluorine pyrrole bacterium acid amides and the composite toxicity test analysis of results table to downy mildew of garpe of white urea cyanogen
As shown in Table 13, fluorine pyrrole bacterium acid amides and white urea cyanogen proportioning are all greater than 1.5 when 1 ︰ 80 ~ 60 ︰ 1 to the synergy ratio SR of downy mildew of garpe, both explanations mixture in 1 ︰ 80 ~ 60 ︰ 1 scope all shows synergistic effect, when the proportioning of fluorine pyrrole bacterium acid amides and white urea cyanogen is at 1 ︰ 30 ~ 10 ︰ 1, synergistic effect is more obviously given prominence to, and synergy ratio is all more than 2.10.Testing through applicant the optimum ratio finding fluorine pyrrole bacterium acid amides and white urea cyanogen is 10:1,8:1,6:1,5:1,4:1,3:1,2:1,1:1,1:2,1:3,1:4,1:5,1:6,1:7,1:8,1:9,1:10,1:12,1:15,1:20,1:25,1:30, especially when fluorine pyrrole bacterium acid amides and white urea cyanogen weight ratio are 1:3, synergy ratio is maximum, and synergistic effect is the most obvious.
Application Example six:
For examination disease: downy mildew of crucifers
Test medicine provides by Shaanxi Meibang Pesticide Co., Ltd..
Experimental scheme: through effective inhibition concentration scope of preliminary experiment determination fluorine pyrrole bacterium acid amides and the former medicine of iprovalicarb or different ratio mixture both it.
Toxicity test result
Table 14 fluorine pyrrole bacterium acid amides and the composite toxicity test analysis of results table to downy mildew of crucifers of iprovalicarb
As shown in Table 14, fluorine pyrrole bacterium acid amides and iprovalicarb proportioning are all greater than 1.5 when 1 ︰ 80 ~ 60 ︰ 1 to the synergy ratio SR of downy mildew of crucifers, both explanations mixture in 1 ︰ 80 ~ 60 ︰ 1 scope all shows synergistic effect, when the proportioning of fluorine pyrrole bacterium acid amides and iprovalicarb is at 1 ︰ 30 ~ 10 ︰ 1, synergistic effect is more obviously given prominence to, and synergy ratio is all more than 2.20.Testing through applicant the optimum ratio finding fluorine pyrrole bacterium acid amides and iprovalicarb is 10:1,8:1,6:1,5:1,4:1,3:1,2:1,1:1,1:2,1:3,1:4,1:5,1:6,1:7,1:8,1:9,1:10,1:12,1:15,1:20,1:25,1:30, especially when fluorine pyrrole bacterium acid amides and iprovalicarb weight ratio are 1:3, synergy ratio is maximum, and synergistic effect is the most obvious.
Through test find: fluorine pyrrole bacterium acid amides and active component B composite after have obvious synergistic effect to the control of downy mildew, peronospora tabacina, powdery mildew, epidemic disease, balck shank, damping off, mould maize ear rot, head blight, leaf mold, root rot, moire disease, leaf spot, net blotch, rust, synergy ratio is all more than 1.50.
Test of pesticide effectiveness part
Test medicine is researched and developed by Shaanxi Meibang Pesticide Co., Ltd., is provided.Contrast medicament: 40% fluorine pyrrole bacterium amide suspending agents (autogamy), 10% cyazofamid suspending agent (autogamy), 50% dimethomorph wetting powder (autogamy), 25% metalaxyl wetting powder (commercial), 8% white urea cyanogen suspending agent (autogamy), 5.5% iprovalicarb wetting powder (autogamy).
Application Example seven fluorine pyrrole bacterium acid amides and active component B or its its compositely prevent and treat the powdery mildew of cucumber test of pesticide effectiveness
This test arrangement is at Xian District, Shanxi Province suburban area, and the investigation powdery mildew of cucumber state of an illness before medicine, in the first time dispenser of state of an illness initial stage, dispenser in every 7 days once, is total to dispenser 2 times.Within after second time dispenser 10 days, 20 days, 45 days, investigate disease index respectively and calculate preventive effect.Experimental result is as follows:
Table 15 fluorine pyrrole bacterium acid amides and active component B or its its compositely prevent and treat the powdery mildew of cucumber test of pesticide effectiveness
As can be seen from Table 15, fluorine pyrrole bacterium acid amides and active component B composite after effectively can prevent and treat powdery mildew of cucumber, control efficiency is all better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example octafluoro pyrrole bacterium acid amides and active component B or its its composite control potato late blight test of pesticide effectiveness
This test arrangement is at Xian District, Shanxi Province suburban area, and the investigation potato late blight state of an illness before medicine, in the first time dispenser of state of an illness initial stage, dispenser in every 7 days once, is total to dispenser 2 times.Within after second time dispenser 15 days, 30 days, 45 days, investigate disease index respectively and calculate preventive effect.Experimental result is as follows:
Table 16 fluorine pyrrole bacterium acid amides and active component B or its its composite control potato late blight test of pesticide effectiveness
As can be seen from Table 16, fluorine pyrrole bacterium acid amides and active component B composite after effectively can prevent and treat potato late blight, control efficiency is all better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example nine fluorine pyrrole bacterium acid amides and active component B or its its compositely prevent and treat the downy mildew of garpe test of pesticide effectiveness
This test arrangement is in Weinan City Dali County, Shaanxi Province, and the investigation downy mildew of garpe state of an illness before medicine, in the first time dispenser of state of an illness initial stage, dispenser in every 7 days once, is total to dispenser 3 times.Within after third time dispenser 7 days, 14 days, 30 days, investigate disease index respectively and calculate preventive effect.Experimental result is as follows:
Table 17 fluorine pyrrole bacterium acid amides and active component B or its its compositely prevent and treat the downy mildew of garpe test of pesticide effectiveness
As can be seen from Table 17, fluorine pyrrole bacterium acid amides and active component B composite after effectively can prevent and treat downy mildew of garpe, control efficiency is all better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example ten fluorine pyrrole bacterium acid amides and active component B or its its compositely prevent and treat the litchi peronospora tabacina test of pesticide effectiveness
This test arrangement is in Huilai county, Guangdong Province, and the investigation litchi peronospora tabacina state of an illness before medicine, in the first time dispenser of state of an illness initial stage, dispenser in every 7 days once, is total to dispenser 2 times.Within after second time dispenser 10 days, 20 days, 45 days, investigate disease index respectively and calculate preventive effect.Experimental result is as follows:
Table 18 fluorine pyrrole bacterium acid amides and active component B or its its compositely prevent and treat the litchi peronospora tabacina test of pesticide effectiveness
As can be seen from Table 18, fluorine pyrrole bacterium acid amides and active component B composite after can effectively prevent and treat litchi peronospora tabacina, control efficiency is all better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example 11 fluorine pyrrole bacterium acid amides and active component B or its its composite control cucumber downy mildew test of pesticide effectiveness
This test arrangement is at Xian District, Shanxi Province suburban area, and the investigation cucumber downy mildew state of an illness before medicine, in the first time dispenser of state of an illness initial stage, dispenser in every 7 days once, is total to dispenser 2 times.Within after second time dispenser 7 days, 14 days, 30 days, investigate disease index respectively and calculate preventive effect.Experimental result is as follows:
Table 19 fluorine pyrrole bacterium acid amides and active component B or its its composite control cucumber downy mildew test of pesticide effectiveness
As can be seen from Table 19, fluorine pyrrole bacterium acid amides and active component B composite after effectively can prevent and treat cucumber downy mildew, control efficiency is all better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example ten difluoro pyrrole bacterium acid amides and active component B or its its composite control black shank test of pesticide effectiveness
This test arrangement is in Weinan City Dengcheng County, Shaanxi Province, and the investigation black shank state of an illness before medicine, in the first time dispenser of state of an illness initial stage, dispenser in every 7 days once, is total to dispenser 2 times.Within after second time dispenser 10 days, 20 days, 45 days, investigate disease index respectively and calculate preventive effect.Experimental result is as follows:
Table 20 fluorine pyrrole bacterium acid amides and active component B or its its composite control black shank test of pesticide effectiveness
As can be seen from Table 20, fluorine pyrrole bacterium acid amides and active component B composite after effectively can prevent and treat black shank, control efficiency is all better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
After draw through tests different local throughout the country, the preventive effect of the Common Diseases such as downy mildew, peronospora tabacina, powdery mildew, epidemic disease, balck shank, damping off, mould maize ear rot, head blight, leaf mold, root rot, moire disease, leaf spot, net blotch, rust effectively can be prevented and treated all more than 95% after fluorine pyrrole bacterium acid amides and cyazofamid, dimethomorph, metalaxyl or its salt, white urea cyanogen, iprovalicarb are composite, be better than single dose preventive effect, synergistic effect is obvious.
Claims (6)
1. the bactericidal composition of a containing fluopyram, it is characterized in that: effective active composition is active components A and active component B, active components A and active component B weight ratio are 1 ︰ 80 ~ 60 ︰ 1, described active components A is fluorine pyrrole bacterium acid amides, and active component B is selected from the one in cyazofamid, dimethomorph, white urea cyanogen, iprovalicarb.
2. the bactericidal composition of containing fluopyram according to claim 1, is characterized in that: the weight ratio of active components A and active component B is 1 ︰ 60 ~ 40 ︰ 1.
3. the bactericidal composition of containing fluopyram according to claim 2, is characterized in that: the weight ratio of fluorine pyrrole bacterium acid amides and cyazofamid is 1 ︰ 30 ~ 15 ︰ 1;
The weight ratio of fluorine pyrrole bacterium acid amides and dimethomorph is 1 ︰ 25 ~ 10 ︰ 1;
The weight ratio of fluorine pyrrole bacterium acid amides and white urea cyanogen is 1 ︰ 30 ~ 10 ︰ 1;
The weight ratio of fluorine pyrrole bacterium acid amides and iprovalicarb is 1 ︰ 30 ~ 10 ︰ 1.
4. the bactericidal composition of any one containing fluopyram according to claims 1 to 3, is characterized in that: composition makes wetting powder, water dispersible granules, suspending agent, suspension emulsion, aqueous emulsion, microemulsion, microcapsule suspending agent, microcapsule suspension-suspendinagent agent.
5. the bactericidal composition of containing fluopyram according to claim 4 is for preventing and treating the application of corps diseases.
6. application according to claim 5, is characterized in that: described disease is downy mildew, peronospora tabacina, powdery mildew, epidemic disease, balck shank, damping off, mould maize ear rot, head blight, leaf mold, root rot, moire disease, leaf spot, net blotch, rust.
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| CN112640754A (en) * | 2020-12-18 | 2021-04-13 | 云南省烟草公司曲靖市公司 | Tobacco seedling raising method capable of effectively reducing incidence rate of tobacco black shank |
| CN113317319A (en) * | 2021-06-21 | 2021-08-31 | 青岛瀚生生物科技股份有限公司 | Composite bactericide and application thereof |
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| CN1917762A (en) * | 2004-02-12 | 2007-02-21 | 拜尔农科股份有限公司 | Fungicidal composition comprising a pyridylethylbenzamide derivative and a compound capable of inhibiting the spores germination or mycelium growth by acting on different metabolic routes |
| CN1918125A (en) * | 2004-02-12 | 2007-02-21 | 拜尔农科股份有限公司 | Fungicidal composition comprising a pyridylethylbenzamide derivative and a compound capable of inhibiting the transport of electrons of the respiratory chain in phytopathogenic fungal organisms |
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| WO2010106008A2 (en) * | 2009-03-16 | 2010-09-23 | Basf Se | Fungicidal compositions comprising fluopyram and metrafenone |
| CN102450266A (en) * | 2010-10-24 | 2012-05-16 | 青岛凯源祥化工有限公司 | Bactericidal composition comprising fluopyram and tebuconazole |
| CN102228032A (en) * | 2011-05-09 | 2011-11-02 | 青岛海利尔药业有限公司 | Bactericidal composition containing fluopyram and famoxadone |
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| CN1674784A (en) * | 2002-08-12 | 2005-09-28 | 拜尔农科股份有限公司 | Novel 2-pyridylethylbenzamide derivative |
| CN1917762A (en) * | 2004-02-12 | 2007-02-21 | 拜尔农科股份有限公司 | Fungicidal composition comprising a pyridylethylbenzamide derivative and a compound capable of inhibiting the spores germination or mycelium growth by acting on different metabolic routes |
| CN1918125A (en) * | 2004-02-12 | 2007-02-21 | 拜尔农科股份有限公司 | Fungicidal composition comprising a pyridylethylbenzamide derivative and a compound capable of inhibiting the transport of electrons of the respiratory chain in phytopathogenic fungal organisms |
| WO2012072660A1 (en) * | 2010-12-01 | 2012-06-07 | Bayer Cropscience Ag | Use of fluopyram for controlling nematodes in crops and for increasing yield |
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| CN112640754A (en) * | 2020-12-18 | 2021-04-13 | 云南省烟草公司曲靖市公司 | Tobacco seedling raising method capable of effectively reducing incidence rate of tobacco black shank |
| CN113317319A (en) * | 2021-06-21 | 2021-08-31 | 青岛瀚生生物科技股份有限公司 | Composite bactericide and application thereof |
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